id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-257539-01s21vh0	Delvecchio, Rodrigo	Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models	2016-11-29		.txt	text/plain	5669	290	52	Immunofluorescence staining corroborated these results ( Figure 1B ) and additionally, chloroquine decreased the production of infectious ( Figure 1C ) and total ( Figure 1D ) virus particles, including defective viral particles, by ZIKV-infected cells. Incubation of Vero cells with chloroquine at 0 h postinfection had a greater impact on the production of ZIKV particles, decreasing viral RNA 64-fold over the controls ( Figure 3A ). To evaluate which step of the viral cycle was susceptible to inhibition, chloroquine was added to Vero cells at different time points post-infection with ZIKV MR766. To evaluate which step of the viral cycle was susceptible to inhibition, chloroquine was added to Vero cells at different time points post-infection with ZIKV MR766. Incubation of Vero cells with chloroquine at 0 h post-infection had a greater impact on the production of ZIKV particles, decreasing viral RNA 64-fold over the controls ( Figure 3A ).	./cache/cord-257539-01s21vh0.txt	./txt/cord-257539-01s21vh0.txt