id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-262944-9k64f0tw	Parker, Elaine L.	Viral-Immune Cell Interactions at the Maternal-Fetal Interface in Human Pregnancy	2020-10-07		.txt	text/plain	9814	497	43	In this review, we describe mechanisms of pathogenicity of two such viral pathogens, Human cytomegalovirus (HCMV) and Zika virus (ZIKV) at the maternal-fetal interface. We will focus on the viruses human Cytomegalovirus (HCMV) and ZIKV, which are known causes of adverse pregnancy outcomes and delve into how they interact with various decidual immune cells to promote their survival and replication. We will explore further the role that NK cells play in specific viral infections in pregnancy TORCH PATHOGENS HCMV Human cytomegalovirus (HCMV) was first described in 1954 by Margaret Smith, who replicated a virus from two newborn babies who had died from cytomegalic inclusion disease (CID) (41) . A study performed using decidual and chorionic villous tissue from early and mid-gestation human pregnancy shows that ZIKV appears to elevate type I and III IFN expression, which does not occur in HCMV infection (131) .	./cache/cord-262944-9k64f0tw.txt	./txt/cord-262944-9k64f0tw.txt