id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-321312-hgp2jwbl	Carvalho, Sandhra M.	Fluorescent Quantum Dots-Zika Virus Hybrid Nanoconjugates for Biolabeling, Bioimaging, and Tracking Host-Cell Interactions	2020-07-10		.txt	text/plain	1901	95	43	title: Fluorescent Quantum Dots-Zika Virus Hybrid Nanoconjugates for Biolabeling, Bioimaging, and Tracking Host-Cell Interactions Thus, we designed and developed for the first time, novel bioconjugates made of Ag-In-S@ZnS (ZAIS) fluorescent quantum dots coupled with ZIKA virus via covalent amide bond with carboxymethylcellulose (CMC) biopolymer for labeling and bioimaging the virus-host cell interactions mechanisms through confocal laser scanning microscopy. This work offers relevant insights regarding the profile of the ZIKA virus-nanoparticle conjugates interactions with VERO cells, which can be applied as a nanoplatform to elucidate the infection mechanisms caused by this viral disease. For biolabeling and bioimaging virus-host cell interactions in vitro, ZIKV_ZAIS conjugates were incubated with VERO cells. The QDs conjugated with ZIKV presented higher entry to VERO cells in comparison to reference QD (ZAIS), indicating the possibility of labeling and detection of ZIKV for tracking the viral infection processes including virus entry and transport in cells. ZAIS-CMC fluorescent conjugates showed insights of ZIKA virus-host cell interactions	./cache/cord-321312-hgp2jwbl.txt	./txt/cord-321312-hgp2jwbl.txt