id author title date pages extension mime words sentences flesch summary cache txt work_4cb2p6ev25hdrima62xmwchwve Pratima Chattopadhyay Global survey of haplotype frequencies and linkage disequilibrium at the RET locus 2003 10 .pdf application/pdf 7654 961 72 polymorphisms (SNPs) and one short tandem repeat polymorphism (STRP)–at the RET locus for samples of markers are polymorphic in all regions of the world and in most individual populations. heterozygosities for the six-site haplotypes range from 82 to 94% for all populations studied except for Association of STRP alleles with the SNP-defined background haplotypes is generally higher Keywords: haplotypes; linkage disequilibrium; population genetics; polymorphisms program, FENGEN.13 Variation in allele and haplotype frequencies across populations was measured as Fst The haplotype labels consist of the alleles present at each of the individual sites, listed in chromosomal order as in Figure 1. Regional averages of the five-SNP haplotype frequencies Figure 3 Regional averages of frequencies of common five-SNP haplotypes. the populations and SNPs. Outside of Africa, the heterozygosities of the exon 2 HaeIII and intron 19 TaqI sites are well-known higher levels of variation in African populations.41,42 As a result, the heterozygosities of the six-site ./cache/work_4cb2p6ev25hdrima62xmwchwve.pdf ./txt/work_4cb2p6ev25hdrima62xmwchwve.txt