id author title date pages extension mime words sentences flesch summary cache txt work_d4mo4orm6zf6powmlgydawdbhe J Theilmann Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene 1989 6 .pdf application/pdf 4761 1021 83 SUMMARY Analysis of many families with linked DNA markers has provided support for the Huntington's disease (HD) gene being close to the telomere on the short arm of chromosome 4. about the precise location of the HD gene relative to these closely linked DNA markers. report an investigation of linkage disequilibrium between six DNA markers and the HD gene in These data suggest that it may be possible to construct high and low risk haplotypes, which may be helpful in DNA analysis and genetic counselling for HD, and represent independent evidence that the gene for HD is centromeric to more distally located DNA markers such as D4S90. TABLE 3 AccI and MboI alleles of HD and non-HD chromosomes by ancestry. Non-random association between alleles detected at D4S95198 and the Huntington's disease gene 679 Non-random association between alleles detected at D4S95198 and the Huntington's disease gene 679 ./cache/work_d4mo4orm6zf6powmlgydawdbhe.pdf ./txt/work_d4mo4orm6zf6powmlgydawdbhe.txt