id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_jrmi4tr3cjfrplb52zl33w5ume	Gustavo A. Patino	Rational Therapy From Bench to Bedside for a Rare Epilepsy	2014		.pdf	text/html	675	117	57	[PDF] Rational Therapy from Bench to Bedside for a Rare Epilepsy | Semantic Scholar Corpus ID: 12353783Rational Therapy from Bench to Bedside for a Rare Epilepsy title={Rational Therapy from Bench to Bedside for a Rare Epilepsy}, author={Gustavo A Patino and J. journal={Epilepsy Currents}, Commentary The Mammalian (also called Mechanistic) Target of Rapamycin (mTOR) is a protein kinase critical for integrating extracellular and intracellular signals to control multiple cell functions, including autophagy, RNA expression and translation, mitochondrial and lipid metabolism, cell polarity and growth, and cytoskeletal organization. mTOR hyperactivation has been linked to many human diseases, among them diabetes, cancer, and developmental brain malformations (1, 2). Sort by Most Influenced Papers Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License	./cache/work_jrmi4tr3cjfrplb52zl33w5ume.pdf	./txt/work_jrmi4tr3cjfrplb52zl33w5ume.txt