id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_pxbiviwifvcirbcmjdb6tuhaaq	Heather A. Bruce	Clinical and genetic validity of quantitative bipolarity	2019	8	.pdf	application/pdf	6219	643	57	whether quantitatively detected subclinical symptoms of bipolarity identifies a heritable trait that infers risk for BP. Quantitative Bipolarity Scale (QBS) was administered to 310 Old Order Amish or Mennonite individuals from multigenerational pedigrees; 110 individuals had psychiatric diagnoses (20 BP, 61 major depressive disorders (MDD), 3 quantitative bipolarity as measured by QBS can separate BP from other psychiatric illnesses yet is significantly heritable diagnosis-based genetic research in BP by taking advantage of the large family structures in the OOA/M, to test Table 1 Sample Demographics, QBS (quantitative bipolarity scale) score and QBS subscores across diagnostic groups Asterisk indicates measure with significant difference (p < 0.5) between bipolar disorder and major depression Fig. 2 QBS (quantitative bipolarity scale) score across diagnostic Table 3 Heritability of QBS (quantitative bipolarity heritable in pedigree samples from the OOA/M population, interestingly even in individuals without BP or psychiatric diagnosis.	./cache/work_pxbiviwifvcirbcmjdb6tuhaaq.pdf	./txt/work_pxbiviwifvcirbcmjdb6tuhaaq.txt