id author title date pages extension mime words sentences flesch summary cache txt work_aietnssxajhyzioqand3rthekm Stefan Brunner Left ventricular functional assessment in murine models of ischemic and dilated cardiomyopathy using [18 F]FDG-PET: comparison with cardiac MRI and monitoring erythropoietin therapy 2012.0 9 .pdf application/pdf 5967 535 62 tomography (FDG-PET) for serial measurements of left ventricular volumes and function in murine models of dilated DCM, ICM and healthy control mice were measured by FDG-PET and compared with reference standard results Results: LV volumes and the LVEF as measured by FDG-PET correlated significantly with the MRI results. underestimated by FDG-PET, with net bias such that LVEF measurements in both models of heart disease exceeded Conclusions: LVEF estimated by ECG-gated FDG-PET significantly correlated with the reference standard MRI, most FDG-PET LVEF measurements in healthy mice, and We then proceeded to test gated FDG-PET for longitudinal monitoring in mice with CVB3-induced DCM after Figure 1 shows representative end-diastolic and endsystolic images of FDG-PET and MRI from the myocardial base to the apex for animals with DCM (A), ICM of measuring murine LVEF with cardiac-gated FDG-PET Table 1 Comparison between LV-functional parameters as calculated by cine MRI and FDG-PET for different study ./cache/work_aietnssxajhyzioqand3rthekm.pdf ./txt/work_aietnssxajhyzioqand3rthekm.txt