id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_3bqwjqbvvrceph7n24hetmrnti	Cecilia Nardini	Bias and Conditioning in Sequential Medical Trials	2013	13	.pdf	application/pdf	5923	780	64	However, evidence from trials stopped early is often chargedwith bias toward implausibly large effects. We contend that conditional hypothesis tests give a superior appreciation of the obtained evidence and significantly improve the practice of sequential medical trials, while staying firmly rooted in is, we have interim looks at the data, and we may decide to stop the trial before the planned sample size is reached. medical trials, unconditional error rates are replaced by conditional error and for observed BðxÞ 5 s, we report conditional error probabilities conditional inference to sequential medical trials. the conditional test still rejects the null, but the probability of error is now First, the assessment of the error probability depends on the observed data and is thus way more informative than in the unconditional This alleviates the interpretational problem mentioned in section 2, since conditional error allows medical readers to assess the confidence	./cache/work_3bqwjqbvvrceph7n24hetmrnti.pdf	./txt/work_3bqwjqbvvrceph7n24hetmrnti.txt