id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_nb4tkpce7zcpfhxaasbyd42ire	Alfred I. Tauber	The Immune System and Its Ecology*	2008	22	.pdf	application/pdf	9485	600	45	concepts adapted from diverse disciplines (i.e., systems philosophy, cybernetics, information theory, computer science) that are applied to biological simulations and model integrated and self-sensing system posed a radical alternative to the selfnon-self Burnetian formulation: In Jerne's theory, self and non-self dissolved as useful parameters of immune organization, because the idiotypic immunology developed in the context of defensive functions, this cooperative biology and its complex teleology have remained obscured by the Elie Metchnikoff formulated immunology's first active theory of immunity within a Darwinian construct (Tauber and Chernyak subject to immune destruction), the wider reference of 'ecological immunology' attempts to determine the costs of defensive mechanisms to This ecological orientation brings issues of communication and information theory directly onto notions of immune regulation, where different Presumably this includes establishing, for various biological systems—cellular (metabolic, genetic), physiological (e.g., immune, neuroendocrine), and ecological—their large-scale organization, regulation, information processing, and integration with other systems.	./cache/work_nb4tkpce7zcpfhxaasbyd42ire.pdf	./txt/work_nb4tkpce7zcpfhxaasbyd42ire.txt