id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_rtk73kxm5rbv3aftiheu4loid4	Christiane Nüsslein-Volhard	Mutations affecting segment number and polarity in Drosophila	1980	30	.pdf	application/pdf	518	116	63	Christiane Nüsslein-Volhard and Eric Wieschaus Christiane Nüsslein-Volhard PhD in biology and genetics in 1973 from studying segmentation development in • Met Nüsslein-Volhard while in Zurich • Moved with Nüsslein-Volhard to EMBL Genes affecting late development • Loss of function of gap genes results in deletions of • Krüppel (Kr) results in lack of thorax and anterior • Knirps (kni) results in the loss of the anterior Knirps: Anterior abdomen genes look like in the developing • Hunchback defines thorax • Knirps defines anterior abdomen segments: Pair-rule genes Even-Skipped: Defining the T1, T3, Defines the denticle band and naked cuticle of even numbered segments segments: Paired and runt segments: Paired and runt Defining Segments in Drosophila Defining Segments in Drosophila Defining Segments in Drosophila Defining segment polarity Segment number is retained, but there is a loss of naked cuticle and a duplication of denticle segment identity polarity genes? Segment polarity genes Segment polarity genes 	./cache/work_rtk73kxm5rbv3aftiheu4loid4.pdf	./txt/work_rtk73kxm5rbv3aftiheu4loid4.txt