Of the reconcileableness of specifick medicines to the corpuscular philosophy to which is annexed a discourse about the advantages of the use of simple medicines / by Robert Boyle ...
         Boyle, Robert, 1627-1691.
      
       
         
           1685
        
      
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             Of the reconcileableness of specifick medicines to the corpuscular philosophy to which is annexed a discourse about the advantages of the use of simple medicines / by Robert Boyle ...
             Boyle, Robert, 1627-1691.
          
           [14], 136 p., [2], 137-225 p.
           
             Printed for Sam. Smith,
             London :
             1685.
          
           
             Reproduction of original in Bristol Public Library, Bristol, England.
          
        
      
    
     
       
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           Medicine -- Early works to 1800.
        
      
    
     
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           OF
           THE
           Reconcileableness
           OF
           SPECIFICK
           MEDICINES
           TO
           THE
           
             Corpuscular
             Philosophy
          
           .
        
         
           To
           which
           is
           Annexed
           A
           Discourse
           about
           the
           Advantages
           Of
           the
           Use
           of
           SIMPLE
           MEDICINES
           .
        
         
           By
           the
           Honourable
           
             ROBERT
             BOYLE
          
           Fellow
           of
           the
           Royal
           Society
           .
        
         
           LONDON
           ,
           Printed
           for
           
             Sam.
             Smith
          
           at
           the'
           
             Princes
             Arms
          
           in
           St.
           Paul's
           Church-Yard
           .
           1685.
           
        
      
       
         
         
           
             
               August
               24.
               
            
          
        
         
           Imprimatur
        
         
           
             Hen.
             Maurice
             ,
             Rmo
             .
             D
             ●o
             .
             W.
             Cant.
             Arch
             po
             .
             a
             sacris
             .
          
        
      
       
         
         
           THE
           PREFACE
           .
        
         
           THE
           rise
           of
           the
           following
           Tract
           ,
           intimated
           near
           the
           beginning
           of
           it
           ,
           was
           not
           such
           a
           fictitious
           thing
           as
           the
           Reader
           may
           imagine
           .
           But
           tho'
           I
           really
           receiv'd
           a
           Visit
           from
           a
           Physician
           ,
           known
           to
           me
           ,
           but
           by
           his
           Reputation
           purposely
           to
           propose
           to
           me
           his
           Objections
           against
           the
           Corpuscular
           Phylosophy
           ,
           and
           he
           had
           a
           long
           conference
           with
           me
           about
           them
           ;
           yet
           ,
           because
           the
           Historical
           passages
           of
           that
           interview
           ,
           cannot
           be
           circumstantially
           related
           in
           few
           words
           ,
           I
           suppose
           the
           Reader
           will
           willingly
           allow
           me
           ,
           to
           imploy
           this
           Preface
           in
           giving
           him
           Advertisements
           about
           the
           scope
           and
           design
           of
           the
           Treatise
           it
           ushers
           in
           .
        
         
           I
           shall
           therefore
           advertise
           him
           ,
           that
           he
           will
           be
           much
           mistaken
           ,
           if
           he
           shall
           expect
           ,
           as
           I
           perceive
           several
           have
           done
           already
           ,
           to
           find
           in
           this
           Book
           a
           Collection
           of
           Receits
           of
           Specifick
           
           Remedies
           .
           For
           a
           moderate
           attention
           to
           the
           Title
           Page
           will
           enable
           him
           manifestly
           to
           discern
           ,
           that
           the
           following
           Paper
           in
           its
           own
           nature
           ,
           and
           in
           the
           direct
           and
           immediate
           design
           of
           it
           ,
           is
           a
           Speculative
           discourse
           ;
           since
           it
           tends
           but
           to
           show
           ,
           that
           ,
           in
           case
           there
           be
           Specifick
           Medicines
           (
           as
           't
           is
           probable
           there
           are
           some
           )
           their
           experienced
           vertues
           are
           reconcilcable
           to
           the
           principles
           of
           the
           Corpuscular
           ,
           or
           (
           as
           many
           call
           it
           )
           the
           new
           Philosophy
           ;
           and
           at
           least
           do
           not
           subvert
           them
           ;
           if
           these
           Effects
           and
           Operations
           be
           not
           clearly
           explicable
           by
           them
           .
           And
           as
           this
           is
           the
           ,
           avowed
           scope
           of
           the
           following
           Essay
           ,
           so
           I
           chose
           to
           treat
           of
           it
           less
           like
           a
           Physician
           than
           a
           Naturalist
           .
           For
           Physicks
           being
           a
           Science
           ,
           whose
           large
           extent
           invites
           and
           warrants
           its
           Cultivaters
           ,
           to
           search
           into
           the
           nature
           and
           Phaenomina
           of
           things
           corporeal
           indefinitely
           ;
           it
           must
           often
           happen
           ,
           that
           the
           Medicinal
           Art
           and
           this
           Science
           will
           be
           conversant
           about
           the
           same
           subject
           ,
           tho'
           in
           differing
           ways
           ,
           and
           with
           differing
           scopes
           .
           
           For
           there
           are
           divers
           hurtful
           or
           advantageous
           accidents
           and
           changes
           of
           the
           humane
           Body
           ,
           whereof
           the
           Naturalist
           takes
           notice
           ,
           but
           as
           they
           are
           Phaenomina
           or
           changes
           produc'd
           by
           Natural
           causes
           in
           the
           Body
           of
           an
           Animal
           ,
           whilst
           the
           Physician
           considers
           them
           as
           Symptoms
           of
           Diseases
           ,
           or
           Effects
           of
           Medicines
           ,
           the
           former
           directing
           his
           Speculations
           to
           the
           discovery
           of
           truth
           ,
           and
           the
           other
           his
           Theory
           to
           the
           recovery
           of
           health
           .
           But
           because
           I
           else
           where
           particularly
           consider
           the
           Cognation
           and
           distinction
           ,
           between
           the
           Discipline
           that
           the
           Naturalist
           ,
           and
           that
           which
           the
           Physician
           cultivates
           ,
           I
           shall
           for
           bear
           to
           mention
           them
           in
           this
           place
           ;
           but
           rather
           acknowledge
           ,
           that
           I
           scarce
           doubt
           but
           that
           I
           might
           have
           inrich'd
           the
           following
           discourse
           with
           some
           choice
           particulars
           ,
           if
           I
           would
           have
           perus'd
           and
           borrow'd
           from
           the
           learned
           writings
           of
           the
           famous
           Dr.
           Willis
           :
           But
           besides
           that
           I
           had
           not
           his
           Books
           at
           hand
           ,
           I
           was
           unwilling
           to
           be
           prepossess'd
           or
           byass'd
           by
           his
           notions
           ,
           and
           I
           presum'd
           
           the
           Person
           I
           wrote
           to
           would
           not
           be
           unwilling
           to
           see
           ,
           what
           ,
           without
           their
           help
           ,
           the
           consideration
           of
           the
           thing
           I
           treated
           of
           suggested
           to
           me
           .
           About
           this
           I
           shall
           now
           proceed
           to
           observe
           ,
           that
           tho'
           the
           direct
           scope
           of
           the
           following
           discourse
           ,
           being
           to
           explicate
           the
           Phaenomena
           of
           some
           bodies
           ,
           which
           from
           their
           use
           ,
           are
           call'd
           Medicinal
           ,
           and
           declare
           how
           possibly
           they
           may
           produce
           the
           Effects
           ascrib'd
           to
           them
           ,
           the
           ensuing
           discourse
           is
           for
           the
           main
           of
           a
           Speculative
           nature
           ;
           yet
           the
           consequences
           that
           may
           be
           drawn
           from
           it
           ,
           and
           the
           applications
           that
           in
           this
           industrious
           Age
           are
           like
           to
           be
           made
           of
           some
           things
           that
           it
           contains
           ,
           may
           probably
           render
           it
           practical
           .
           For
           I
           have
           more
           than
           once
           observ'd
           ,
           that
           divers
           considerable
           Remedies
           ,
           and
           some
           not
           unpromising
           methods
           too
           ,
           have
           either
           remain'd
           unthought
           of
           ,
           both
           by
           many
           Galenical
           Physicians
           ,
           and
           divers
           of
           their
           modern
           Antagonists
           too
           ,
           or
           if
           propos'd
           by
           others
           ,
           have
           been
           rejected
           or
           slighted
           ,
           barely
           upon
           this
           supposition
           ,
           
           that
           no
           rational
           account
           can
           be
           given
           of
           their
           way
           of
           working
           ,
           or
           how
           they
           should
           do
           good
           ,
           and
           't
           is
           said
           to
           be
           unworthy
           of
           a
           rational
           Physician
           ;
           to
           make
           use
           of
           a
           Remedy
           ,
           of
           whose
           manner
           of
           operating
           he
           cannot
           give
           a
           reason
           .
           How
           prejudicial
           it
           may
           be
           to
           many
           Patients
           ,
           that
           Physicians
           be
           prepossess'd
           with
           a
           bad
           opinion
           of
           an
           useful
           Remedy
           ,
           may
           be
           guess'd
           by
           him
           that
           shall
           consider
           ,
           what
           multitudes
           of
           Teeming
           Women
           ,
           that
           probably
           might
           have
           been
           sav'd
           by
           the
           skilful
           use
           of
           Phlebotomy
           ,
           have
           been
           suffer'd
           to
           dye
           for
           want
           of
           it
           ,
           upon
           a
           dislike
           of
           that
           Remedy
           that
           Physicians
           for
           many
           Ages
           thought
           to
           be
           grounded
           upon
           no
           less
           authority
           than
           a
           positive
           Aphorism
           of
           Hippocrates
           .
           And
           therefore
           if
           ,
           to
           remove
           the
           specious
           objection
           newly
           mention'd
           against
           that
           whole
           kind
           of
           Remedies
           call'd
           Specificks
           ,
           the
           following
           Tract
           has
           been
           so
           happy
           as
           to
           show
           ,
           that
           't
           is
           at
           least
           possible
           ,
           that
           Medicines
           said
           to
           be
           Specifick
           ,
           may
           perform
           their
           operations
           by
           ways
           ,
           which
           tho'
           
           not
           explicable
           by
           the
           vulgar
           Doctrine
           of
           the
           Schools
           ,
           are
           intelligible
           ,
           and
           reconcileable
           ,
           to
           the
           clear
           Principles
           of
           the
           Mechanical
           Phylosophy
           :
           If
           ,
           I
           say
           ,
           this
           have
           been
           done
           by
           the
           Theory
           propos'd
           in
           this
           Treatise
           ,
           it
           may
           conduce
           somewhat
           to
           inlarge
           the
           minds
           of
           many
           Physicians
           ,
           and
           invite
           them
           to
           make
           use
           of
           several
           Remedies
           ,
           of
           which
           they
           did
           not
           think
           ,
           or
           against
           which
           they
           were
           prejudic'd
           .
           And
           since
           Specificks
           ,
           where
           they
           can
           be
           had
           ,
           are
           wont
           to
           be
           free
           from
           any
           immoderate
           manifest
           quality
           ,
           and
           for
           the
           most
           part
           to
           work
           more
           benignly
           ,
           as
           well
           as
           more
           effectually
           ,
           
             caeteris
             paribus
          
           ,
           than
           other
           Medicines
           ;
           I
           think
           that
           to
           bring
           them
           into
           due
           request
           ,
           and
           invite
           Physicians
           to
           search
           for
           new
           ones
           ,
           as
           well
           as
           imploy
           those
           already
           known
           ,
           may
           tend
           much
           to
           shorten
           many
           Cures
           ,
           and
           make
           them
           more
           easy
           and
           more
           safe
           .
        
         
           
             Est
             aliquid
             prodire
             tenus
             si
             non
             datur
             Vltra
             .
          
        
      
       
         
         
           THE
           Advertisement
           OF
           THE
           PUBLISHER
           .
        
         
           
             THE
             Author
             had
             occasion
             to
             touch
             upon
             some
             of
             the
             same
             Subjects
             that
             he
             here
             treats
             of
             ,
             in
             a
             Book
             ,
          
           The
           Usefulness
           of
           Experimental
           Philosophy
           ,
           
             long
             since
             publisht
             ;
             but
             he
             had
             the
             misfortune
             to
             be
             reduc'd
             to
             write
             the
             following
             Discourse
             about
          
           Specifick
           Medicines
           ,
           
             and
             the
             Utility
             of
          
           Simple
           Remedies
           ,
           
             in
             a
             Village
             where
          
           he
           had
           not
           that
           Book
           at
           hand
           ,
           and
           could
           not
           call
           to
           mind
           all
           that
           he
           had
           therein
           published
           seventeen
           or
           eighteen
           
           years
           before
           :
           On
           which
           account
           ,
           though
           he
           studiously
           forbore
           to
           repeat
           the
           particulars
           that
           he
           remembred
           to
           have
           set
           down
           in
           that
           Treatise
           ,
           how
           opposite
           soever
           they
           would
           have
           been
           to
           his
           present
           purpose
           ,
           yet
           having
           since
           the
           following
           Discourse
           was
           sent
           to
           the
           Press
           ,
           got
           a
           sight
           of
           that
           other
           (
           which
           he
           had
           not
           read
           in
           many
           years
           )
           he
           finds
           upon
           a
           transient
           View
           that
           some
           of
           the
           same
           things
           are
           mentioned
           in
           both
           Books
           :
           at
           which
           discovery
           ,
           though
           he
           be
           somewhat
           troubled
           ,
           yet
           he
           is
           the
           less
           so
           ,
           because
           they
           are
           but
           few
           ,
           in
           comparison
           of
           the
           new
           ones
           ,
           and
           set
           down
           on
           such
           occasions
           ,
           or
           with
           such
           other
           circumstances
           ,
           that
           may
           make
           a
           favourable
           Reader
           look
           on
           them
           ,
           as
           not
           bare
           repetitions
           .
           And
           tho'
           in
           the
           forecited
           Treatise
           ,
           some
           of
           the
           motives
           to
           make
           use
           of
           simple
           Medicines
           ,
           be
           lightly
           touch'd
           ,
           yet
           besides
           ,
           that
           they
           are
           not
           all
           that
           are
           mention'd
           in
           the
           following
           invitation
           ,
           those
           arguments
           that
           are
           there
           but
           pointed
           at
           ,
           are
           here
           treated
           of
           ,
           and
           both
           confirm'd
           ,
           and
           explain'd
           by
           other
           Observations
           ,
           and
           Receits
           .
           And
           since
           the
           Printed
           Book
           above
           mention'd
           has
           been
           
           for
           divers
           years
           very
           scarce
           ,
           't
           is
           presum'd
           that
           those
           many
           Readers
           that
           have
           it
           not
           ,
           will
           not
           be
           displeas'd
           to
           find
           here
           some
           few
           things
           for
           which
           they
           cannot
           resort
           thither
           :
           And
           as
           the
           Author
           foresaw
           he
           might
           be
           oblig'd
           to
           consent
           to
           the
           translation
           of
           the
           following
           papers
           into
           the
           Roman
           Tongue
           ,
           so
           he
           thought
           his
           Latine
           Readers
           would
           not
           repine
           ,
           tho'
           a
           great
           number
           of
           particulars
           had
           been
           borrow'd
           of
           a
           Book
           that
           is
           not
           yet
           extant
           in
           their
           Language
           .
        
         
           I
           shall
           give
           you
           no
           farther
           account
           of
           the
           particulars
           contain'd
           in
           the
           two
           ensuing
           Treatises
           ,
           since
           the
           title
           pages
           give
           a
           sufficient
           hint
           of
           the
           Noble
           Authors
           main
           scope
           ,
           and
           chief
           design
           ,
           I
           shall
           only
           say
           ,
           that
           the
           first
           Treatise
           effectually
           performs
           what
           has
           not
           been
           as
           yet
           attempted
           by
           answering
           a
           very
           considerable
           objection
           against
           the
           Doctrine
           of
           the
           Corpuscularian
           Philosophers
           ,
           namely
           ,
           that
           which
           is
           taken
           from
           what
           we
           call
           Specifick
           Medicines
           ,
           
             their
             vertues
             ,
             and
             operations
             being
             hitherto
             judg'd
             by
             several
             of
             the
             learnedest
             sort
             wholly
             irreconcileable
             to
             the
             principles
             of
             the
             new
             Philosophy
             ;
             
             whereby
             he
             gratifieth
             not
             only
             the
             curiosity
             of
             Speculative
             Philosophers
             ,
             but
             does
             likewise
             a
             notable
             piece
             of
             Service
             to
             all
             Physicians
             ,
             ushering
             in
             here
             and
             there
             such
             notions
             as
             may
             be
             the
             Principles
             of
             a
             sure
             ,
             and
             easie
             Practice
             ,
             yea
             and
             enable
             them
             too
             ,
             to
             give
             a
             good
             account
             of
             their
             own
             Receits
             ;
             I
             mean
             of
             those
             that
             contain
             Specifick
             Medicines
             ,
             whose
             vertues
             hitherto
             we
             could
             not
             describe
             to
             our
          
           Patients
           ,
           
             but
             by
             saying
             they
             did
             work
             we
             knew
             not
             how
             ,
             or
             by
             some
          
           Specifick
           ,
           
             that
             is
             by
             some
             occult
             or
             hidden
          
           quality
           .
           
             The
             second
             Treatise
             ,
             which
             is
             an
             Invitation
             to
             the
             use
             of
             simple
             Medicines
             ,
             is
             of
             such
             a
             general
             use
             ,
             that
             Mankind
             is
             much
             indebted
             to
             this
             Noble
             Author
             for
             it
             ,
             't
             is
             so
             well
             grounded
             both
             upon
             Reason
             ,
             and
             Experience
             ,
             that
             this
             as
             well
             as
             the
             foremention'd
             discourse
             ,
             does
             fully
             answer
             the
             great
             repute
             of
             the
             Author
             both
             at
             home
             ,
             and
             abroad
             ,
             where
             he
             is
             commonly
             stil'd
             the
          
           English
           Phylosopher
           .
        
      
       
         
         
           The
           Publisher
           thought
           fit
           to
           translate
           for
           the
           benefit
           of
           every
           common
           Reader
           ,
           some
           Latine
           passages
           contained
           in
           the
           foregoing
           Treatises
           .
        
         
           P.
           70.
           
           
             From
             the
             year
             of
             our
             Lord
             1645.
             in
             the
             space
             of
             fourteen
             years
             I
             cur'd
             above
             a
             thousand
             Frebricitants
             without
             Bleeding
             ,
             Purging
             ,
             or
             Sweating
             ,
             by
             the
             help
             of
             a
             single
             precipitating
             Remedy
             ,
             without
             any
             regard
             to
             the
             nature
             of
             the
             Feaver
             ,
             whether
             it
             were
             intermittent
             ,
             or
             continued
             ,
             whether
             it
             were
             a
          
           Tertian
           ,
           
             or
             a
          
           Quartan
           ,
           
             which
             is
             harder
             to
             cure
             than
             any
             other
             ,
             yea
             without
             considering
             any
             other
             circumstance
             either
             of
             Time
             ,
             Place
             ,
             Sex
             ,
             or
             Age
             ,
             and
             that
             in
             a
             very
             short
             time
             ,
             without
             any
             danger
             of
             Relapse
             ,
             and
             without
             any
             considerable
             trouble
             of
             the
             Patient
             ,
             if
             through
             his
             own
             .
             Intemperance
             ,
             he
             fell
             not
             into
             new
             Fits
             again
             .
          
        
         
           Kergerus
           de
           fermentati
           Sect.
           3.
           cap.
           3.
           p.
           mihi
           250.
           
        
         
         
           P.
           130.
           
           
             I
             have
             made
             my self
             a
             frequent
             trial
             of
             this
             Stone
             ,
             having
             carried
             several
             of
             those
             little
             Stones
             tyed
             together
             about
             my
             Neck
             in
             such
             a
             manner
             ,
             that
             the
             Stones
             did
             touch
             the
             Mouth
             of
             my
             Stomach
             ,
             yet
             they
             were
             beneficial
             ,
             tho
             they
             had
             nothing
             graven
             upon
             'em
             ,
          
           &c.
           
        
         
           Galen
           .
           de
           simpl
           .
           med
           .
           facul
           .
           1.
           9.
           tit
           .
           de
           lap
           .
        
         
           P.
           131.
           
           We
           have
           seen
           sometimes
           the
           Hemerods
           cured
           ,
           as
           likewise
           the
           copious
           monthly
           issues
           by
           wearing
           Rings
           made
           of
           this
           Stone
           .
        
         
           Nic.
           Monard
           .
           simpl
           .
           med
           .
           histo
           .
           c.
           36
           P.
           329.
           
        
      
    
     
       
         
         
           OF
           THE
           Reconcileableness
           of
           Specifick
           Medicines
           ,
           TO
           THE
           Corpuscular
           Philosophy
           .
        
         
           
             The
             Introduction
             ,
             To
             my
             Learned
             Friend
             ,
             Dr.
             F.
             
          
           
             
               SIR
               ,
            
          
           
             PErceiving
             ,
             by
             our
             late
             Conference
             ,
             that
             the
             thing
             which
             most
             alienates
             you
             ,
             from
             the
             Corpuscular
             Philosophy
             ,
             is
             an
             Objection
             drawn
             from
             your
             own
             Profession
             and
             Experience
             ,
             namely
             ,
             that
             the
             Specifick
             Vertues
             of
             Medicines
             
             are
             not
             reconcileable
             to
             it
             ;
             my
             unwillingness
             that
             an
             Hypothesis
             ,
             I
             am
             so
             kind
             to
             as
             I
             am
             to
             the
             Mechanical
             ,
             should
             continue
             under
             the
             disfavour
             of
             a
             Person
             I
             so
             much
             esteem
             ,
             as
             I
             do
             Dr.
             F.
             makes
             me
             venture
             to
             offer
             you
             the
             annexed
             Paper
             ,
             thô
             it
             be
             but
             an
             Inlargement
             of
             a
             dismembred
             part
             of
             what
             I
             long
             since
             ,
             to
             gratify
             a
             Friend
             ,
             noted
             about
             the
             
               Origine
               or
               Production
               of
               Occult
               Qualities
               .
            
             For
             thô
             I
             pretend
             not
             ,
             that
             this
             Trifle
             should
             satisfy
             a
             man
             of
             your
             Judgment
             and
             Learning
             ,
             yet
             it
             may
             perhaps
             serve
             to
             keep
             you
             from
             thinking
             it
             impossible
             ,
             that
             a
             skilful
             Pen
             may
             be
             able
             quite
             to
             surmount
             those
             Difficulties
             ,
             that
             so
             bad
             a
             Pen
             as
             mine
             is
             capable
             of
             lessening
             .
          
        
         
           
           
             A
             Paper
             belonging
             to
             the
             writings
             about
             the
             Mechanical
             Origine
             of
             Qualities
             .
          
           
             AMong
             the
             several
             kinds
             of
             occult
             qualities
             that
             ,
             which
             is
             afforded
             by
             Specifick
             Vertues
             of
             Medicines
             ,
             is
             not
             here
             to
             be
             pretermitted
             .
             For
             these
             Qualities
             do
             not
             only
             ,
             like
             other
             hidden
             ones
             ,
             invite
             ,
             our
             curiosity
             ,
             but
             concern
             our
             health
             and
             may
             hereafter
             (
             if
             I
             mistake
             not
             )
             appear
             to
             be
             of
             much
             greater
             importance
             ,
             than
             as
             yet
             they
             are
             commonly
             thought
             .
             However
             it
             may
             be
             worth
             while
             to
             take
             some
             notice
             of
             them
             in
             this
             place
             ,
             if
             it
             were
             but
             because
             divers
             Learned
             Physicians
             do
             ,
             as
             some
             of
             themselves
             owned
             to
             me
             ,
             reject
             or
             disfavour
             the
             Corpuscular
             Philosophy
             upon
             this
             account
             ,
             That
             they
             think
             it
             cannot
             be
             reconcil'd
             to
             the
             vertues
             of
             Specifick
             Remedies
             ,
             or
             at
             least
             cannot
             ,
             either
             in
             a
             particular
             or
             in
             a
             general
             way
             ,
             give
             any
             tolerable
             account
             of
             them
             .
          
           
           
             I
             find
             three
             sorts
             of
             Qualities
             mention'd
             in
             the
             Books
             of
             physicians
             ,
             under
             the
             notion
             of
             
               Specifick
               Vertues
            
             .
             For
             by
             some
             a
             Medicine
             is
             said
             to
             have
             a
             Specifick
             Faculty
             ,
             because
             it
             is
             eminently
             and
             peculiarly
             friendly
             to
             this
             or
             that
             particular
             Part
             of
             the
             Body
             ,
             as
             the
             Heart
             ,
             the
             Brain
             ,
             the
             Eye
             ,
             &c.
             
             By
             others
             it
             is
             said
             ,
             by
             a
             Specifick
             Power
             ,
             to
             attract
             and
             evacuate
             some
             determinate
             Humour
             ,
             as
             Choler
             ,
             Phlegm
             ,
             &c
             But
             the
             most
             usual
             account
             ,
             upon
             which
             a
             Medicine
             is
             said
             to
             be
             Specifick
             ,
             is
             that
             it
             has
             the
             vertue
             to
             cure
             ,
             by
             some
             hidden
             property
             ,
             this
             or
             that
             particular
             disease
             ,
             as
             a
             Pleurisy
             ,
             an
             Asthma
             ,
             the
             colick
             ,
             the
             Dropsy
             ,
             &c.
             
             And
             this
             being
             the
             principal
             and
             most
             common
             sense
             ,
             in
             which
             the
             word
             Specifick
             is
             employ'd
             by
             Physicians
             ,
             I
             shall
             ordinarily
             make
             use
             of
             it
             ,
             in
             that
             sense
             ,
             in
             the
             following
             discourse
             ,
             but
             yet
             without
             so
             confining
             my self
             to
             it
             ,
             as
             not
             to
             consider
             it
             in
             the
             two
             other
             senses
             ,
             when
             occasion
             shall
             require
             .
          
           
             But
             before
             I
             descend
             to
             particular
             
             considertions
             't
             will
             not
             be
             amiss
             to
             obviate
             mistakes
             by
             declaring
             ,
             in
             what
             sense
             in
             this
             Paper
             ,
             I
             shall
             employ
             the
             Term
             
               Specifick
               Medicine
            
             ,
             especially
             in
             the
             last
             of
             the
             three
             foremention'd
             Acceptions
             .
          
           
             I
             do
             not
             then
             by
             a
             Specifick
             understand
             a
             Medicine
             ,
             that
             will
             cure
             the
             disease
             it
             is
             good
             for
             Infallibly
             ,
             and
             in
             all
             Persons
             that
             take
             it
             ,
             for
             I
             confess
             I
             never
             yet
             met
             with
             any
             such
             remedy
             .
             Nor
             do
             I
             by
             Specifick
             understand
             a
             Medicine
             that
             ,
             almost
             like
             a
             Charm
             ,
             works
             only
             by
             some
             latent
             and
             unaccountable
             Property
             ,
             without
             the
             assistance
             of
             any
             known
             Quality
             ,
             as
             Purgative
             ,
             Diuretick
             ,
             Sudorific
             ,
             &c.
             to
             be
             found
             in
             other
             Medicines
             :
             But
             by
             Specifick
             I
             mean
             ,
             in
             this
             discourse
             ,
             such
             a
             medicine
             as
             very
             often
             ,
             if
             not
             most
             commonly
             ,
             does
             very
             considerably
             ,
             and
             better
             than
             ordinary
             Medicines
             ,
             relieve
             the
             Patient
             ,
             whether
             by
             quite
             curing
             ,
             or
             much
             lessening
             ,
             his
             disease
             ,
             and
             which
             acts
             principally
             upon
             the
             account
             of
             some
             Property
             or
             peculiar
             vertue
             ;
             so
             that
             
             if
             it
             have
             any
             manifest
             Quality
             that
             is
             friendly
             ,
             yet
             the
             good
             it
             does
             is
             greater
             ,
             than
             can
             reasonably
             be
             ascribed
             to
             the
             degree
             it
             has
             of
             that
             manifest
             Quality
             ,
             as
             hot
             ,
             cold
             ,
             bitter
             ,
             sudorifick
             ,
             &c.
             
          
           
             There
             are
             two
             grand
             Questions
             ,
             that
             may
             be
             propos'd
             about
             the
             Specifick
             vertues
             ascrib'd
             to
             Medicines
             ,
             The
             first
             is
             ,
             whether
             there
             be
             really
             any
             such
             ,
             and
             the
             second
             whether
             ,
             if
             there
             be
             ,
             the
             Mechanical
             Hypothesis
             can
             be
             accommodated
             to
             them
             .
          
           
             The
             former
             of
             these
             Questions
             may
             admit
             of
             a
             double
             sense
             ,
             for
             it
             may
             be
             propos'd
             with
             respect
             ,
             either
             to
             the
             present
             measure
             of
             our
             knowledge
             ,
             or
             to
             those
             further
             attainments
             that
             ,
             in
             future
             times
             ,
             men
             may
             arrive
             at
             .
          
           
             In
             the
             latter
             of
             these
             senses
             ,
             (
             to
             dispatch
             first
             the
             consideration
             of
             that
             )
             I
             shall
             not
             presume
             to
             maintain
             ,
             without
             restriction
             ,
             either
             part
             of
             the
             Question
             .
             For
             I
             do
             not
             only
             hope
             ,
             but
             am
             apt
             to
             think
             ,
             that
             in
             time
             
             the
             Industry
             and
             Sagacity
             of
             men
             will
             be
             able
             to
             discover
             Intelligible
             causes
             of
             most
             of
             those
             Qualities
             ,
             that
             now
             pass
             for
             Occult
             ,
             and
             among
             them
             of
             many
             of
             the
             Specifick
             vertues
             ascrib'd
             to
             Medicines
             .
             And
             yet
             ,
             on
             the
             other
             side
             ,
             I
             much
             fear
             that
             men
             will
             not
             be
             successful
             ,
             in
             tracing
             out
             the
             true
             and
             immediate
             causes
             of
             those
             good
             effects
             of
             some
             remedies
             ,
             that
             depend
             upon
             such
             fine
             and
             uncommon
             Textures
             ,
             and
             such
             latent
             and
             odly
             guided
             Motions
             ,
             as
             fall
             not
             under
             our
             Senses
             ,
             thô
             perhaps
             assisted
             by
             Instruments
             .
             Which
             conjecture
             will
             appear
             the
             less
             improbable
             ,
             if
             we
             consider
             those
             admirable
             Idiosyncrasiae
             ,
             or
             Peculiarities
             of
             Disposition
             ,
             whereof
             the
             Books
             of
             eminent
             Writers
             afford
             us
             many
             instances
             ,
             to
             whose
             number
             I
             could
             ,
             upon
             my
             own
             Observation
             ,
             add
             several
             ,
             if
             I
             thought
             it
             needful
             .
             And
             ,
             thô
             I
             am
             not
             ignorant
             that
             some
             of
             these
             may
             be
             plausibly
             accounted
             for
             ,
             as
             that
             of
             some
             mens
             aversion
             to
             cheese
             ,
             or
             to
             cats
             ;
             yet
             I
             do
             not
             think
             that
             the
             like
             explications
             
             can
             be
             extended
             to
             some
             others
             ,
             that
             might
             be
             nam'd
             ,
             if
             it
             were
             here
             pertinent
             to
             discuss
             that
             throughly
             .
          
           
             As
             to
             the
             former
             sense
             ,
             of
             the
             Question
             lately
             propounded
             ,
             I
             confess
             my self
             very
             amiable
             to
             the
             Affirmative
             ,
             as
             far
             as
             I
             can
             judge
             by
             those
             writings
             of
             Physicians
             I
             have
             had
             occasion
             to
             peruse
             .
             Which
             limitation
             I
             add
             ,
             because
             I
             would
             not
             derogate
             from
             the
             knowledge
             of
             particular
             persons
             ,
             who
             in
             so
             learned
             and
             inquisitive
             an
             Age
             ,
             may
             be
             arriv'd
             at
             far
             greater
             attainments
             than
             those
             Physicians
             have
             done
             ,
             that
             have
             entertain'd
             the
             Publick
             about
             the
             Occult
             and
             Specifick
             Qualities
             of
             Medicines
             .
          
           
             I
             know
             there
             have
             been
             ,
             and
             still
             are
             ,
             Dogmatical
             Physitians
             ,
             that
             upon
             the
             Principles
             ,
             as
             they
             pretend
             ,
             of
             the
             School-Philosophy
             ,
             reject
             all
             Medicinal
             vertues
             that
             they
             think
             not
             reducible
             to
             manifest
             Qualities
             .
             But
             of
             such
             Galen
             somewhere
             justly
             complains
             ,
             that
             they
             either
             deny
             matters
             
             of
             fact
             ,
             or
             assign
             very
             incompetent
             causes
             o
             the
             effects
             they
             pretend
             to
             explain
             .
             And
             ,
             for
             my
             part
             ,
             I
             am
             so
             far
             from
             believing
             these
             men
             capable
             of
             giving
             sufficient
             reasons
             of
             the
             more
             hidden
             Properties
             of
             Medicins
             ,
             that
             I
             am
             not
             apt
             to
             think
             them
             able
             ,
             by
             their
             Principles
             ,
             to
             give
             clear
             and
             particular
             explications
             ,
             even
             of
             the
             more
             easy
             and
             familiar
             vertues
             of
             simples
             .
          
           
             I
             am
             therefore
             dispos'd
             to
             think
             that
             ,
             in
             the
             sense
             formerly
             deliver'd
             of
             the
             Term
             
               Specifick
               Medicines
            
             ,
             there
             are
             some
             Remedies
             that
             deserve
             that
             name
             .
          
           
             To
             this
             opinion
             I
             have
             been
             led
             by
             several
             Reasons
             ▪
             And
             first
             (
             to
             begin
             with
             the
             least
             weighty
             )
             it
             has
             the
             suffrage
             of
             many
             learned
             Physicians
             ,
             both
             Ancient
             and
             Modern
             ,
             and
             particularly
             that
             of
             Galen
             himself
             in
             several
             places
             of
             his
             Works
             .
             And
             I
             remember
             that
             ,
             treating
             of
             a
             Specifick
             Remedy
             against
             the
             biting
             of
             a
             mad
             Dog
             ,
             which
             vertue
             he
             ascribes
             to
             an
             occult
             Quality
             ,
             or
             ,
             as
             he
             speaks
             ,
             to
             
             the
             Propriety
             of
             the
             whole
             Substance
             ;
             
             he
             takes
             occasion
             to
             promise
             ,
             that
             he
             would
             write
             a
             Book
             of
             things
             that
             operate
             upon
             that
             account
             .
             Which
             Book
             ,
             if
             it
             had
             scap'd
             with
             his
             other
             Works
             (
             for
             he
             elsewhere
             cites
             it
             as
             having
             written
             it
             )
             would
             probably
             have
             furnish'd
             us
             with
             several
             things
             to
             strengthen
             our
             opinion
             .
             And
             thô
             in
             Matters
             Philosophical
             I
             am
             little
             sway'd
             by
             mere
             Authority
             ,
             yet
             the
             concurrent
             suffrage
             ,
             of
             many
             eminent
             Physicians
             ,
             may
             in
             this
             controversy
             be
             the
             more
             considerable
             ,
             because
             most
             of
             them
             ,
             being
             noted
             Practitioners
             ,
             had
             opportunity
             to
             observe
             whether
             or
             no
             any
             Remedies
             deserv'd
             the
             name
             of
             Specificks
             :
             And
             their
             Testimony
             is
             ,
             in
             our
             case
             ,
             the
             more
             to
             be
             regarded
             ,
             because
             Physicians
             ,
             especially
             famous
             ones
             ,
             are
             not
             wont
             to
             be
             willing
             to
             acknowledge
             ,
             that
             there
             are
             Effects
             ,
             which
             fall
             under
             the
             Cognisance
             of
             their
             art
             ,
             whereof
             they
             cannot
             give
             the
             causes
             .
          
           
             My
             next
             Inducement
             ,
             to
             admit
             
             Specificks
             ,
             is
             founded
             upon
             Parity
             of
             Reason
             :
             For
             't
             is
             manifest
             ,
             that
             there
             are
             divere
             formidable
             Maladies
             ,
             that
             are
             produc'd
             by
             inconsiderable
             quantities
             of
             Poysons
             ,
             that
             have
             not
             been
             discover'd
             to
             produce
             such
             great
             and
             dismal
             Effects
             by
             any
             Manifest
             Quality
             ,
             whether
             first
             ,
             second
             ,
             or
             third
             ,
             as
             Medical
             Authors
             (
             I
             doubt
             not
             over
             accurately
             )
             distinguish
             them
             .
          
           
             On
             this
             occasion
             I
             shall
             add
             a
             very
             odd
             Accident
             ,
             about
             which
             I
             was
             advis'd
             with
             by
             an
             expert
             oculist
             ,
             very
             soon
             after
             it
             happen'd
             :
             The
             Case
             was
             this
             .
             A
             man
             lying
             somewhat
             long
             in
             Bed
             in
             the
             morning
             ,
             and
             chancing
             ,
             as
             he
             lay
             upon
             his
             Back
             ,
             to
             cast
             up
             his
             Eyes
             to
             the
             Tester
             ,
             saw
             a
             great
             Spider
             ,
             that
             stood
             still
             just
             over
             his
             Face
             :
             Wherefore
             having
             reproach'd
             his
             Wife
             ,
             who
             happen'd
             to
             be
             in
             the
             Room
             ,
             with
             gross
             negligence
             ,
             she
             took
             a
             Broom
             ,
             and
             struck
             it
             upon
             the
             upper
             part
             of
             the
             Tester
             ,
             to
             beat
             down
             the
             Spider
             ;
             but
             the
             Animal
             held
             so
             fast
             with
             his
             Feet
             that
             she
             miss'd
             her
             aim
             ,
             and
             he
             ,
             whether
             frighted
             
             or
             irritated
             by
             this
             rude
             shake
             ,
             let
             fall
             upon
             the
             Man
             ,
             that
             was
             staring
             at
             it
             to
             see
             what
             would
             happen
             ,
             a
             drop
             of
             Liquor
             that
             lighted
             directly
             upon
             one
             of
             his
             open
             Eyes
             .
             But
             finding
             no
             heat
             nor
             sharpness
             insue
             ,
             but
             rather
             a
             very
             sensible
             coldness
             ,
             he
             made
             nothing
             of
             it
             ,
             but
             rose
             and
             put
             on
             his
             cloth's
             .
             But
             presently
             after
             ,
             happening
             to
             rub
             with
             his
             finger
             the
             other
             Eye
             ,
             he
             was
             sadly
             surpriz'd
             to
             find
             himself
             suddenly
             benighted
             ,
             and
             calling
             for
             assistance
             ,
             he
             found
             that
             the
             Eye
             ,
             which
             the
             Spider
             had
             let
             fall
             something
             on
             ,
             thô
             no
             change
             were
             noted
             in
             it
             by
             the
             by-standers
             ,
             was
             totally
             depriv'd
             of
             sight
             .
             Upon
             which
             score
             he
             repair'd
             to
             the
             above
             mention'd
             Oculists
             :
             But
             whether
             he
             afterwards
             recover'd
             his
             sight
             or
             no
             ,
             I
             cannot
             tell
             ;
             all
             the
             endeavours
             the
             Oculist
             arid
             I
             imploy'd
             to
             find
             out
             his
             Lodging
             (
             to
             which
             it
             seems
             he
             had
             left
             a
             wrong
             direction
             )
             having
             been
             Fruitless
             .
             This
             brought
             into
             my
             mind
             ,
             that
             I
             had
             sometimes
             wonder'd
             to
             see
             how
             much
             more
             quickly
             Spiders
             
             will
             kill
             Flyes
             ,
             than
             the
             cutting
             off
             their
             Heads
             ,
             or
             running
             them
             quite
             through
             with
             Pins
             or
             Needles
             will
             do
             .
          
           
             But
             to
             return
             to
             what
             I
             was
             saying
             ,
             of
             the
             great
             Mischief
             done
             to
             Humane
             Bodies
             ,
             by
             very
             small
             quantities
             of
             Poyson
             ;
             methinks
             one
             may
             thence
             argue
             that
             it
             seems
             not
             improbable
             that
             Appropriated
             Medicines
             ,
             especially
             when
             administred
             in
             greater
             quantity
             ,
             may
             produce
             very
             notable
             changes
             in
             the
             Humane
             Body
             to
             the
             advantage
             of
             it
             .
             But
             on
             this
             occasion
             I
             expect
             to
             be
             told
             ,
             that
             't
             is
             much
             more
             easy
             to
             do
             harm
             ,
             than
             good
             ,
             and
             I
             confess
             't
             is
             so
             in
             the
             general
             ,
             but
             yet
             ,
             in
             the
             particular
             case
             before
             us
             ,
             I
             consider
             that
             some
             Poysons
             ,
             that
             produce
             such
             dreadful
             Symptoms
             in
             the
             Body
             ,
             are
             frequently
             cur'd
             by
             their
             appropriated
             Antidotes
             ,
             which
             therefore
             must
             have
             a
             Sanative
             Power
             great
             enough
             ,
             with
             the
             help
             but
             of
             the
             ordinary
             Concourse
             of
             Nature
             ,
             to
             surmount
             the
             efficacy
             of
             the
             venemous
             Matter
             .
             To
             which
             I
             shall
             add
             this
             more
             familiar
             instance
             
             that
             as
             Perfumes
             do
             often
             enough
             produce
             various
             ,
             and
             sometimes
             frightful
             ,
             Symptoms
             in
             many
             Histerical
             Women
             ;
             so
             the
             fumes
             of
             the
             burnt
             Feathers
             of
             Patridges
             ,
             Woodcocks
             ,
             &c.
             do
             frequently
             cure
             the
             Fit
             in
             as
             little
             time
             as
             the
             sweet
             smell
             procur'd
             it
             .
             And
             I
             have
             often
             found
             the
             smell
             of
             strong
             Spirit
             of
             Harts-horn
             ,
             or
             Sal-Armoniac
             ,
             recover
             such
             Women
             in
             far
             less
             time
             ,
             than
             the
             fragrant
             odours
             imploy'd
             to
             make
             them
             si●●
             .
          
           
             The
             Third
             and
             Principal
             Inducement
             I
             had
             ,
             to
             think
             there
             are
             Specifick
             Remedies
             ,
             is
             from
             Experience
             .
             I
             might
             urge
             ,
             on
             this
             occasion
             ,
             the
             Testimony
             of
             Galen
             ,
             who
             tells
             us
             more
             than
             once
             ,
             that
             he
             himself
             therefore
             confided
             ,
             in
             the
             Ashes
             of
             burnt
             Craw-Fishes
             ,
             for
             the
             cure
             of
             the
             biting
             of
             a
             Mad
             Dog
             ,
             because
             never
             any
             of
             those
             that
             took
             it
             dy'd
             .
             And
             to
             annex
             that
             upon
             the
             by
             ,
             for
             the
             usefulness
             of
             it
             ,
             he
             adds
             ,
             that
             thô
             the
             effect
             of
             these
             ashes
             be
             admirable
             ,
             
             even
             when
             
             given
             alone
             ,
             yet
             their
             vertue
             may
             be
             increased
             ,
             by
             adding
             to
             ten
             parts
             of
             burnt
             Craw
             Fishes
             five
             of
             Gentian
             and
             one
             of
             Frank-incense
             .
             And
             the
             great
             vertue
             of
             these
             burnt
             Shell-fishes
             I
             find
             to
             have
             been
             taken
             notice
             of
             some
             ages
             before
             
               Galen
               ;
               Dioscorides
            
             much
             commending
             them
             against
             the
             same
             Disease
             that
             the
             Pergamenian
             does
             .
          
           
             I
             shall
             in
             this
             place
             purposely
             forbear
             to
             mention
             such
             Medicines
             ,
             as
             ,
             thô
             by
             divers
             learned
             Physicians
             commended
             as
             Specificks
             ,
             are
             yet
             by
             others
             much
             question'd
             ,
             if
             not
             flatly
             deny'd
             to
             be
             so
             .
             Since
             it
             may
             be
             more
             proper
             ,
             and
             may
             perhaps
             suffice
             ,
             to
             mention
             two
             or
             three
             ,
             whose
             efficacy
             is
             more
             notorious
             .
          
           
             'T
             is
             known
             ,
             by
             almost
             daily
             experience
             ,
             in
             Italy
             and
             divers
             other
             hot
             Countreys
             ,
             that
             thô
             the
             stings
             of
             Scorpions
             oftentimes
             produce
             very
             acute
             Pains
             ,
             and
             formidable
             Symptoms
             ,
             yet
             the
             Mischief
             is
             easily
             remedy'd
             ,
             either
             by
             presently
             crushing
             the
             Body
             of
             the
             Scorpion
             upon
             the
             
             Hurt
             ,
             or
             by
             anointing
             the
             part
             affected
             with
             Oyl
             of
             Scorpions
             ,
             (
             for
             that
             reason
             to
             be
             almost
             every
             where
             found
             ,
             )
             which
             being
             made
             by
             suffocating
             those
             Insects
             in
             common
             Oyl
             ,
             and
             keeping
             it
             long
             in
             the
             Sun
             ,
             the
             Liquor
             does
             not
             at
             all
             appear
             to
             have
             any
             manifest
             Quality
             ,
             to
             which
             its
             sanative
             Efficacy
             may
             be
             ascribed
             .
          
           
             The
             Bitings
             of
             those
             Serpents
             ,
             which
             for
             the
             noise
             they
             are
             wont
             to
             make
             ,
             with
             a
             kind
             of
             empty
             Bladders
             in
             their
             Tails
             ,
             the
             English
             call
             Rattle-snakes
             ,
             are
             counted
             much
             more
             poysonous
             and
             dangerous
             than
             the
             stings
             of
             Scorpions
             .
             Of
             which
             I
             remember
             a
             learned
             Eye
             witness
             ,
             that
             liv'd
             divers
             years
             in
             Virginia
             ,
             where
             they
             much
             abound
             ,
             related
             to
             me
             a
             very
             strange
             Instance
             ,
             which
             I
             cannot
             now
             stay
             to
             set
             down
             .
             And
             yet
             the
             English
             Planters
             ,
             when
             they
             have
             the
             misfortune
             to
             be
             bitten
             by
             these
             Serpents
             ,
             are
             wont
             to
             cure
             themselves
             very
             happily
             by
             the
             use
             of
             that
             plant
             ,
             which
             from
             its
             effects
             ,
             and
             the
             place
             it
             grows
             
             in
             ,
             is
             well
             known
             by
             the
             name
             of
             
               Virginian
               Snakeweed
            
             ,
             [
             
               or
               Serpentaria
               Virginiana
            
             .
          
           
             That
             the
             
               Peruvian
               Bark
            
             ,
             commonly
             call'd
             here
             in
             England
             the
             
               Jesuits
               Powder
            
             ,
             is
             a
             Specifick
             against
             Agues
             ,
             particularly
             Quartans
             ,
             divers
             learned
             Physicians
             not
             only
             grant
             but
             assert
             .
             And
             I
             remember
             the
             justly
             famous
             Dt.
             Willis
             gave
             me
             this
             Character
             of
             it
             in
             private
             discourse
             ,
             (
             not
             without
             taking
             notice
             that
             some
             decry'd
             it
             ,
             )
             
               'T
               is
               the
               noblest
               Medicine
               we
            
             (
             meaning
             the
             Physicians
             )
             know
             .
             But
             thô
             I
             will
             not
             dispute
             ,
             whether
             it
             be
             so
             certain
             and
             safe
             a
             Specifick
             for
             Agues
             ,
             as
             't
             is
             believ'd
             by
             ,
             divers
             eminent
             Doctors
             ,
             yet
             I
             think
             it
             can
             scarce
             be
             deny'd
             ,
             to
             be
             a
             Specifick
             Medicine
             to
             stop
             the
             fits
             of
             Agues
             ,
             (
             in
             the
             notion
             of
             
               Specifick
               Remedies
            
             formerly
             deliver'd
             )
             since
             it
             does
             that
             far
             more
             effectually
             ,
             than
             the
             generality
             of
             Physicians
             ,
             for
             many
             ages
             ,
             were
             wont
             to
             do
             ,
             with
             their
             other
             Antifebrile
             Medicines
             .
          
           
             I
             might
             here
             tell
             you
             ,
             that
             I
             have
             
             my self
             seen
             a
             stone
             ,
             whose
             efficacy
             in
             stopping
             Hemorrhagies
             invited
             my
             Wonder
             ;
             and
             another
             ,
             which
             perform'd
             extraordinary
             things
             in
             more
             than
             one
             Distemper
             thô
             I
             could
             not
             perceive
             that
             either
             of
             them
             did
             these
             things
             by
             any
             manifest
             Quality
             .
             And
             I
             might
             here
             add
             some
             other
             particulars
             ,
             that
             may
             be
             borrow'd
             from
             Experience
             ,
             in
             favour
             of
             our
             opinion
             ,
             but
             that
             't
             is
             like
             they
             will
             be
             more
             properly
             alledg'd
             hereafter
             in
             some
             places
             of
             the
             remaining
             Part
             of
             our
             Discourse
             .
          
           
             I
             know
             those
             ,
             that
             have
             rejected
             Specifick
             Medicines
             ,
             have
             confidently
             urg'd
             three
             plausible
             Arguments
             against
             them
             .
             For
             some
             Physicians
             deny
             there
             are
             any
             Effects
             of
             Medicines
             so
             considerable
             ,
             as
             to
             make
             them
             deserve
             the
             name
             of
             
               Specifick
               .
               Others
            
             would
             probably
             allow
             that
             Experience
             favours
             our
             opinion
             ,
             if
             they
             did
             not
             think
             the
             way
             of
             a
             Specifick
             Medicines
             operating
             must
             be
             inexplicable
             ,
             and
             consequently
             ought
             not
             be
             admitted
             by
             Physicians
             .
             And
             others
             
             again
             (
             being
             of
             Sentiments
             very
             differing
             from
             these
             )
             will
             allow
             them
             to
             be
             very
             efficacious
             ,
             but
             endeavour
             to
             derive
             their
             whole
             Efficacy
             from
             Manifest
             Qualities
             ,
             as
             heat
             ,
             cold
             ,
             tenuity
             of
             Parts
             ,
             faculty
             of
             making
             large
             Evacuations
             by
             Vomit
             ,
             Siege
             ,
             &c.
             
          
           
             But
             these
             objections
             will
             be
             more
             opportunely
             consider'd
             in
             due
             places
             ,
             Only
             there
             is
             one
             Argument
             ,
             that
             may
             be
             objected
             by
             the
             deniers
             of
             Specifick
             remedies
             ,
             which
             I
             confess
             is
             so
             specious
             ,
             as
             to
             deserve
             to
             be
             particularly
             examin'd
             in
             this
             place
             ,
             lest
             it
             should
             ,
             if
             unremov'd
             ,
             beget
             too
             strong
             a
             prejudice
             against
             a
             great
             part
             of
             the
             ensuing
             Discourse
             .
             For
             it
             may
             be
             said
             ,
             that
             a
             Medicine
             taken
             in
             at
             the
             Mouth
             must
             ,
             in
             the
             Stomach
             and
             Guts
             ,
             be
             at
             lest
             very
             much
             chang'd
             by
             Digestion
             ,
             and
             the
             Aliments
             it
             meets
             with
             there
             ,
             and
             a
             good
             Part
             of
             it
             will
             be
             proscrib'd
             among
             excrements
             .
             That
             alter
             it
             has
             pass'd
             out
             of
             the
             Stomach
             ,
             it
             must
             meet
             with
             divers
             strainers
             of
             differing
             Textures
             ,
             which
             will
             probably
             stop
             all
             or
             most
             of
             the
             
             Medicinal
             Corpuscles
             that
             would
             pervade
             them
             .
             And
             that
             if
             any
             shal
             be
             so
             lucky
             ,
             or
             so
             penetrating
             ,
             as
             to
             surmount
             all
             these
             obstacles
             ,
             they
             will
             probably
             either
             be
             assimilated
             unto
             the
             Substance
             of
             the
             Body
             ,
             or
             quite
             chang'd
             by
             the
             parts
             they
             will
             be
             fain
             to
             combine
             with
             there
             .
             Or
             ,
             if
             yet
             any
             should
             be
             able
             so
             obstinately
             to
             retain
             their
             pristine
             Nature
             ,
             they
             will
             in
             all
             likely
             hood
             be
             too
             few
             to
             have
             any
             considerable
             operation
             upon
             the
             Body
             .
             But
             to
             this
             plausible
             objection
             I
             have
             several
             things
             to
             oppose
             by
             way
             of
             Answer
             .
          
           
             1.
             
             And
             first
             I
             may
             represent
             ,
             that
             divers
             Specifick
             Medicines
             ,
             as
             some
             some
             Oyntments
             ,
             Plaisters
             ,
             Poultis's
             Amulets
             ,
             
               Pericarpia
               ,
               &c.
            
             
             Being
             outwardly
             apply'd
             ,
             their
             Corpuscles
             can
             get
             into
             the
             Mass
             of
             Blood
             without
             passing
             through
             the
             Stomach
             ,
             and
             consequently
             are
             not
             concern'd
             in
             the
             propos'd
             objection
             .
          
           
             2.
             
             Against
             most
             of
             the
             Galenical
             Physicians
             ,
             that
             are
             wont
             to
             urge
             
             the
             formerly
             propos'd
             objection
             ,
             I
             see
             not
             why
             one
             may
             not
             argue
             
               ad
               hominem
            
             by
             putting
             them
             in
             mind
             ,
             that
             the
             same
             Difficulties
             for
             the
             main
             ,
             or
             others
             not
             inferior
             ,
             may
             be
             alledged
             against
             a
             common
             opinion
             of
             their
             own
             .
             For
             since
             they
             believe
             that
             Purgatives
             ,
             Cordials
             ,
             Diaphoreticks
             ,
             besides
             Cephalicks
             ,
             Hepaticks
             ,
             and
             some
             other
             sorts
             of
             Medicines
             ,
             do
             contemperate
             ,
             and
             sweeten
             the
             Blood
             ,
             and
             usefully
             affect
             the
             newly
             mentioned
             stable
             Parts
             ;
             and
             since
             these
             Medicines
             act
             not
             by
             naked
             Qualities
             but
             by
             small
             Particles
             ,
             of
             their
             own
             substance
             ,
             if
             they
             can
             give
             us
             an
             intelligible
             account
             of
             the
             ingress
             of
             these
             Particles
             in
             considerable
             numbers
             ,
             into
             the
             Recesses
             of
             the
             Body
             ,
             without
             being
             ,
             dispoyl'd
             of
             their
             particular
             virtues
             ,
             they
             will
             at
             the
             same
             time
             instruct
             us
             ,
             how
             to
             answer
             the
             objection
             they
             urge
             against
             us
             .
          
           
             3.
             
             And
             in
             regard
             the
             generality
             of
             Physicians
             hold
             ,
             that
             Milk
             ,
             and
             Urine
             ,
             were
             materially
             in
             the
             Mass
             
             of
             Blood
             ,
             and
             are
             separated
             from
             it
             by
             the
             Breasts
             ,
             and
             Kidneys
             ;
             I
             think
             one
             may
             by
             experience
             shew
             she
             invalidity
             of
             their
             ratiocination
             against
             Specificks
             .
             For
             't
             is
             obvious
             to
             observe
             ,
             and
             I
             have
             several
             times
             done
             it
             my self
             ,
             that
             Rubarb
             will
             (
             perhaps
             for
             many
             hours
             )
             tinge
             the
             Urine
             of
             those
             that
             take
             any
             considerable
             dose
             of
             it
             And
             in
             some
             of
             our
             
               English
               American
            
             Colonies
             ,
             there
             grows
             a
             fruit
             ,
             which
             the
             planters
             call
             the
             
               Prickled
               Pear
            
             ,
             whose
             inward
             Substance
             is
             exceeding
             red
             ,
             and
             whose
             being
             pleasant
             in
             tast
             ,
             as
             well
             as
             colour
             ,
             frequently
             invites
             eaters
             ;
             but
             its
             Juice
             is
             of
             so
             penetrating
             a
             nature
             ,
             that
             it
             passes
             from
             the
             stomach
             into
             the
             Bladder
             ,
             and
             then
             into
             the
             chamber-pot
             ,
             with
             so
             little
             loss
             of
             its
             redness
             ,
             that
             strangers
             are
             wont
             to
             be
             surpris'd
             and
             frighted
             at
             it
             ,
             as
             thinking
             this
             unknown
             fruit
             had
             made
             them
             void
             bloody
             Urine
             ,
             if
             not
             blood
             rather
             than
             Urine
             .
             This
             is
             a
             known
             thing
             among
             those
             ,
             that
             have
             dwelt
             in
             our
             Southern
             Plantations
             ,
             and
             has
             
             been
             affirm'd
             to
             me
             by
             unsuspected
             Eye-witnesses
             ,
             and
             among
             them
             by
             a
             famous
             Physician
             .
             As
             for
             Milk
             ,
             the
             great
             Hippocrates
             himself
             informs
             us
             ,
             that
             if
             a
             Woman
             ,
             or
             a
             she-goat
             take
             Elaterium
             ,
             the
             Cathartick
             vertue
             passes
             into
             the
             Milk
             ,
             and
             will
             purge
             the
             Child
             that
             drinks
             it
             .
             And
             I
             remember
             that
             haying
             occasion
             to
             make
             some
             stay
             ,
             in
             the
             Spring
             or
             beginning
             of
             Summer
             ,
             in
             the
             confines
             of
             Switzerland
             and
             Savoy
             ,
             I
             had
             the
             opportunity
             to
             observe
             this
             odd
             Phaenomenon
             ,
             That
             when
             the
             Cows
             ,
             in
             that
             District
             ,
             fed
             ,
             as
             they
             would
             in
             that
             season
             plentifully
             do
             ,
             upon
             a
             certain
             weed
             ,
             said
             to
             be
             a
             kind
             of
             Wild-Garlick
             ,
             that
             grew
             copiously
             in
             the
             Pastures
             ,
             the
             very
             Butter
             made
             of
             their
             Milk
             had
             so
             rank
             a
             tast
             of
             the
             Herb
             ,
             that
             though
             I
             was
             not
             ,
             yet
             divers
             other
             strangers
             were
             ,
             thereby
             diverted
             from
             eating
             of
             it
             ,
             though
             otherwise
             fresh
             and
             good
             .
             And
             I
             remember
             too
             ,
             that
             having
             pass'd
             a
             Winter
             on
             the
             Sea-coast
             of
             the
             County
             of
             Cork
             in
             Ireland
             ,
             I
             found
             it
             a
             known
             observation
             ,
             
             that
             a
             sort
             of
             greedy
             Sea-fowl
             ,
             whose
             name
             comes
             not
             now
             into
             my
             mind
             ,
             living
             almost
             wholly
             upon
             Fish
             ,
             (
             upon
             whose
             scholes
             I
             have
             sometimes
             wondered
             to
             see
             such
             a
             multitude
             of
             ravenous
             Fowls
             attending
             )
             they
             acquire
             a
             Tast
             that
             makes
             some
             pleasantly
             Question
             ,
             whether
             the
             food
             they
             afford
             be
             to
             be
             reputed
             flesh
             or
             fish
             .
             But
             how
             constantly
             the
             Particles
             of
             divers
             Bodies
             may
             retain
             their
             nature
             in
             all
             the
             digestion
             ,
             and
             strainers
             they
             pass
             through
             ,
             I
             have
             more
             amply
             discours'd
             in
             another
             Tract
             ,
             
               About
               the
               concealments
               and
               disguises
               of
               seminal
               Principles
               .
            
             And
             I
             presume
             I
             have
             here
             said
             enough
             ,
             to
             allow
             me
             to
             proceed
             to
             the
             fourth
             part
             of
             my
             answer
             .
          
           
             4.
             
             I
             consider
             then
             ,
             in
             the
             last
             place
             ,
             that
             whereas
             't
             is
             objected
             ,
             that
             so
             small
             a
             quantity
             of
             the
             matter
             of
             a
             Specifick
             ,
             as
             is
             able
             to
             retain
             its
             nature
             when
             it
             arrives
             at
             the
             part
             it
             should
             work
             on
             ,
             must
             have
             little
             or
             no
             power
             left
             to
             relieve
             it
             .
             This
             difficulty
             will
             not
             much
             stagger
             those
             
             that
             know
             ,
             how
             unsafe
             it
             is
             to
             measure
             the
             power
             that
             natural
             Agents
             may
             have
             ,
             to
             work
             upon
             such
             an
             engine
             as
             the
             Humane
             Body
             ,
             by
             their
             bulk
             rather
             than
             by
             their
             subtilty
             and
             and
             activity
             A
             sober
             Gentleman
             ,
             that
             was
             Governour
             of
             a
             Colony
             in
             the
             Torrid
             one
             ,
             and
             commanded
             a
             Warlike
             English
             Vessel
             ,
             that
             sail'd
             up
             very
             far
             in
             the
             great
             River
             of
             Gambia
             or
             Gambra
             in
             Africk
             ,
             and
             staid
             there
             some
             time
             to
             trade
             with
             the
             Negro's
             of
             the
             Inland
             Countrey
             ,
             being
             inquired
             of
             by
             me
             ,
             among
             other
             things
             ,
             about
             the
             Poysons
             that
             are
             said
             to
             be
             extraordinarily
             powerful
             in
             the
             Parts
             he
             came
             from
             ;
             he
             answered
             me
             ,
             that
             the
             Blacks
             had
             a
             Poyson
             ,
             that
             was
             ,
             though
             somewhat
             slow
             ,
             yet
             very
             mortal
             ;
             in
             so
             small
             a
             dose
             ,
             that
             it
             was
             usual
             for
             them
             to
             hide
             enough
             of
             it
             to
             kill
             a
             man
             ,
             under
             one
             of
             their
             Nails
             ,
             which
             they
             wear
             somewhat
             long
             :
             Whence
             they
             would
             drop
             it
             so
             dextrously
             into
             the
             Drink
             ,
             or
             Milk
             ,
             or
             Broth
             or
             other
             Liquid
             Aliment
             of
             those
             they
             ow
             a
             spite
             to
             ,
             that
             't
             is
             scarce
             
             possible
             for
             a
             stranger
             to
             be
             watchful
             enough
             to
             prevent
             it
             .
             For
             which
             reason
             ,
             as
             he
             told
             me
             ,
             though
             he
             sometimes
             eat
             with
             their
             petty
             Princes
             ,
             or
             Governours
             ,
             at
             the
             same
             table
             ,
             yet
             he
             would
             never
             eat
             out
             of
             the
             same
             dish
             ,
             nor
             drink
             out
             of
             the
             same
             Cups
             with
             any
             of
             them
             .
             He
             added
             that
             ,
             in
             another
             part
             of
             Africa
             ,
             a
             famous
             Knight
             ,
             who
             commanded
             the
             English
             there
             ,
             and
             lately
             died
             a
             ship-board
             in
             his
             way
             home
             ,
             was
             so
             poysoned
             at
             a
             parting
             Treat
             ,
             by
             a
             young
             Negro
             Woman
             of
             Quality
             ,
             whom
             he
             had
             enjoy'd
             and
             declin'd
             to
             take
             with
             him
             ,
             according
             to
             his
             promise
             ,
             into
             Europe
             .
             And
             though
             my
             Relator
             early
             gave
             him
             notice
             of
             what
             he
             suspected
             to
             be
             the
             cause
             of
             this
             Indisposition
             ,
             and
             engag'd
             him
             thereupon
             to
             take
             Antidotes
             ,
             and
             Cordials
             ,
             as
             Treacle
             ,
             &c.
             yet
             his
             languishing
             distemper
             still
             increased
             ,
             till
             it
             kill'd
             him
             .
          
           
             I
             could
             name
             a
             Vegetable
             Substance
             ,
             growing
             in
             Europe
             ,
             and
             perhaps
             not
             far
             from
             hence
             ,
             which
             though
             some
             Empiricks
             employ
             as
             a
             Medicine
             ,
             is
             
             so
             violently
             ,
             operative
             ,
             that
             a
             Learned
             and
             famous
             Modern
             Physitian
             relates
             ,
             that
             no
             more
             than
             half
             a
             grain
             would
             work
             so
             violently
             ,
             as
             to
             cause
             very
             dangerous
             Hypercatharses
             ,
             of
             which
             though
             he
             remedy'd
             some
             ,
             yet
             he
             was
             not
             able
             to
             keep
             all
             from
             being
             Mortal
             .
             And
             because
             many
             ingenious
             men
             deny
             that
             out
             English
             Vipers
             are
             poysonous
             ,
             I
             shall
             add
             in
             favour
             of
             the
             Argument
             that
             I
             have
             been
             enforcing
             that
             I
             know
             a
             Young
             man
             ,
             who
             having
             been
             bitten
             by
             an
             English
             Viper
             ,
             which
             he
             too
             rashly
             laid
             hold
             on
             ,
             though
             the
             tooth
             pricked
             but
             his
             hand
             ,
             yet
             the
             venom
             ,
             convey'd
             by
             so
             small
             a
             hurt
             which
             perhaps
             equal'd
             not
             in
             quantity
             the
             hundredth
             part
             of
             Pins
             head
             ,
             quickly
             produc'd
             in
             him
             the
             bad
             Symptoms
             that
             usually
             follow
             the
             Biteing
             of
             that
             Serpent
             ,
             ;
             And
             among
             others
             (
             for
             I
             particularly
             ask'd
             him
             about
             that
             )
             a
             violent
             vomiting
             of
             ill
             condition'd
             stuff
             .
             I
             know
             also
             a
             person
             ,
             that
             practis'd
             Physick
             in
             the
             Isle
             of
             Iava
             ,
             where
             Scorpions
             are
             held
             to
             be
             more
             
             venemous
             than
             in
             Italy
             who
             having
             ,
             after
             he
             had
             drank
             some
             what
             freely
             ,
             provok'd
             ,
             and
             bin
             stung
             by
             ,
             a
             Scorpion
             ,
             thô
             the
             Hurt
             was
             but
             in
             his
             Thumb
             ,
             and
             was
             so
             small
             that
             I
             could
             not
             perceive
             the
             least
             scar
             it
             had
             left
             ,
             that
             it
             put
             him
             presently
             to
             such
             violent
             tortures
             ,
             for
             some
             hours
             ,
             till
             he
             had
             procur'd
             Specifick
             remedies
             ,
             that
             he
             look'd
             upon
             himself
             a
             dead
             man
             ;
             and
             felt
             so
             raging
             a
             heat
             within
             that
             he
             thought
             (
             to
             use
             his
             own
             Expression
             )
             that
             hell-fire
             was
             got
             into
             his
             Body
             .
             Nor
             is
             it
             only
             by
             mere
             poysons
             ,
             that
             a
             Humane
             Body
             may
             be
             greatly
             affected
             ,
             thô
             the
             agent
             be
             but
             very
             inconsiderable
             for
             bulk
             and
             weight
             ,
             for
             we
             see
             ,
             that
             divers
             Women
             ,
             otherwise
             strong
             and
             healthy
             ,
             will
             be
             cast
             into
             sounding
             fits
             ,
             and
             perhaps
             will
             complain
             of
             suffocation
             ,
             and
             be
             put
             into
             convulsive
             Motions
             ,
             by
             the
             fragrant
             Odours
             of
             Musk
             ,
             or
             Civet
             ;
             though
             if
             all
             the
             Effluvia
             ,
             that
             cause
             these
             Symptomes
             ,
             were
             reduc'd
             into
             one
             aggregate
             ,
             this
             would
             not
             probably
             amount
             to
             a
             hundredth
             ,
             nor
             perhaps
             to
             a
             thousandth
             ,
             
             part
             of
             a
             grain
             .
             And
             I
             have
             oftentimes
             speedily
             suppress'd
             such
             fits
             ,
             by
             the
             odour
             of
             the
             volatile
             Salts
             Harts-horn
             ,
             Sal
             Armoniac
             ,
             or
             the
             like
             ,
             or
             of
             destill'd
             Spirits
             abounding
             with
             such
             Salts
             ;
             though
             perhaps
             all
             the
             Particles
             ,
             that
             actually
             relieved
             the
             patient
             ,
             and
             calm'd
             these
             frightful
             Symptoms
             ,
             if
             pack'd
             together
             ,
             would
             not
             have
             equal'd
             ,
             either
             in
             bigness
             or
             in
             weight
             ,
             the
             tenth
             ,
             not
             to
             say
             the
             fifteenth
             ,
             or
             the
             hundredth
             ,
             part
             of
             a
             grain
             of
             mustard-seed
             .
             And
             as
             for
             inward
             remedies
             ,
             't
             is
             vulgarly
             known
             ,
             that
             in
             the
             infusion
             of
             
               Crocus
               Metallorum
            
             ,
             Corpuscles
             that
             render
             the
             Liquor
             vehemently
             vomitive
             and
             Purgative
             ,
             are
             so
             very
             minute
             ,
             that
             great
             proportions
             of
             Wine
             ,
             or
             other
             Vehicles
             may
             ▪
             be
             strongly
             impregnated
             with
             them
             without
             any
             sensible
             diminution
             of
             the
             Body
             that
             parts
             with
             them
             .
             And
             of
             this
             we
             have
             a
             not
             less
             ,
             if
             not
             more
             ,
             considerable
             instance
             ,
             when
             Quick-Silver
             is
             decocted
             or
             long
             infus'd
             in
             common
             Water
             .
             For
             Helmont
             observes
             that
             ,
             
             though
             the
             Liquor
             be
             not
             altered
             in
             Colour
             ,
             or
             Tast
             ,
             nor
             the
             Quick-silver
             at
             all
             sensibly
             chang'd
             ,
             nay
             nor
             grown
             any
             thing
             lighter
             in
             a
             ballance
             ,
             yet
             the
             Liquor
             does
             ,
             by
             means
             of
             these
             insensible
             and
             unponderable
             Effluxes
             of
             the
             Quicksilver
             ,
             acquire
             a
             notable
             virtue
             against
             worms
             ;
             for
             which
             purpose
             not
             only
             Helmont
             ,
             but
             before
             him
             that
             experienc'd
             Chymist
             Hartman
             ,
             and
             another
             eminent
             Writer
             ,
             extoll
             this
             Medicine
             .
             And
             on
             this
             occasion
             I
             remember
             that
             a
             fine
             Boy
             ,
             born
             to
             be
             heir
             to
             a
             very
             illustrious
             family
             ,
             falling
             into
             a
             dangerous
             Feaver
             ,
             which
             was
             judg'd
             to
             proceed
             from
             worms
             or
             verminous
             matter
             ;
             a
             famous
             and
             Experienc'd
             Physitian
             ,
             that
             treated
             him
             ,
             confess'd
             to
             me
             ,
             that
             he
             was
             out
             of
             hopes
             of
             him
             ;
             Because
             the
             Child
             ,
             having
             been
             bred
             to
             have
             his
             will
             ,
             and
             tir'd
             with
             unsuccessful
             Remedies
             ,
             was
             so
             obstinate
             and
             carefull
             in
             refusing
             to
             take
             any
             thing
             ,
             that
             smeld
             or
             relish'd
             of
             a
             Medicine
             ,
             that
             he
             forbore
             ,
             in
             spite
             of
             all
             the
             art
             us'd
             to
             deceive
             him
             ,
             even
             to
             drink
             
             any
             thing
             but
             small
             Beer
             Whereupon
             I
             perswaded
             both
             the
             Doctor
             ,
             and
             the
             Lord
             ,
             whose
             son
             the
             child
             was
             ,
             to
             impregnate
             his
             small
             beer
             with
             Mercurial
             particles
             ,
             by
             frequently
             shaking
             it
             with
             good
             Quick-silver
             in
             it
             .
             By
             which
             means
             the
             patient
             ,
             perceiving
             no
             change
             of
             Colour
             or
             Tast
             in
             the
             Drink
             ,
             swallow'd
             it
             greedily
             ,
             and
             through
             the
             blessing
             of
             God
             was
             soon
             after
             restor'd
             to
             a
             Health
             ,
             which
             the
             Parties
             concern'd
             ascrib'd
             to
             the
             Mercurial
             remedy
             .
          
           
             I
             should
             condemn
             my self
             ,
             for
             having
             bestowed
             so
             many
             words
             upon
             one
             objection
             ,
             but
             that
             I
             hope
             the
             Answer
             ,
             given
             to
             it
             in
             this
             place
             ,
             will
             facilitate
             and
             shortens
             several
             things
             relating
             to
             my
             present
             Subject
             
               Specifick
               Medicines
            
             .
             About
             which
             I
             shall
             now
             proceed
             to
             offer
             my
             thougths
             in
             some
             Propositions
             ,
             and
             short
             discourses
             upon
             them
             .
          
           
             Having
             now
             dispatch'd
             the
             first
             of
             the
             two
             formerly
             propos'd
             Inquiries
             ,
             I
             proceed
             to
             the
             second
             ,
             namely
             ,
             whether
             the
             Mechanical
             Hypothesis
             
             can
             be
             accommodated
             to
             Specifick
             Medicines
             ,
             so
             as
             that
             they
             may
             be
             either
             intelligibly
             explicated
             by
             a
             ,
             or
             at
             least
             shown
             to
             be
             reconcilable
             to
             it
             .
             I
             presume
             you
             will
             easily
             believe
             ,
             that
             there
             are
             few
             writers
             more
             inclinable
             ,
             than
             I'am
             ,
             to
             confess
             the
             dimness
             of
             our
             knowledge
             ,
             and
             the
             obscurity
             of
             many
             things
             in
             nature
             ;
             or
             that
             are
             more
             forward
             than
             I
             to
             grant
             ,
             that
             many
             of
             the
             operations
             ,
             of
             Specifick
             Medicines
             ,
             are
             to
             be
             reckoned
             among
             those
             abstruse
             things
             ,
             whereof
             nature
             seems
             to
             affect
             the
             concealment
             .
             But
             notwithstanding
             this
             ,
             when
             I
             consider
             how
             comprehensive
             and
             fertile
             the
             principles
             of
             the
             Corpuscular
             Philosophy
             are
             ,
             I
             cannot
             despair
             bur
             that
             it
             will
             be
             found
             ,
             that
             divers
             of
             the
             effects
             of
             these
             Medicines
             may
             be
             ,
             in
             a
             general
             way
             explicated
             by
             them
             ,
             and
             not
             any
             will
             appear
             inconsistent
             with
             them
             .
             This
             I
             desire
             may
             be
             here
             taken
             notice
             of
             once
             for
             all
             that
             ,
             retaining
             the
             Scope
             of
             the
             following
             discourse
             still
             in
             your
             memory
             ,
             you
             may
             not
             think
             
             it
             strange
             ,
             that
             I
             content
             my self
             ,
             on
             most
             occasions
             ,
             to
             give
             in
             general
             possible
             explications
             ,
             and
             to
             shew
             that
             Specifick
             Medicines
             may
             operate
             on
             some
             such
             account
             as
             I
             propose
             ,
             without
             affirming
             that
             they
             certainly
             do
             so
             I
             observ'd
             soon
             after
             the
             beginning
             of
             this
             Paper
             that
             there
             were
             three
             sorts
             of
             virtues
             to
             which
             Physicians
             (
             thô
             not
             unanimously
             )
             have
             given
             this
             Title
             of
             Specifick
             ;
             namely
             such
             as
             evacuate
             some
             particular
             humour
             ,
             such
             as
             are
             peculiarly
             friendly
             to
             this
             or
             that
             part
             of
             the
             Humane
             Body
             ,
             and
             such
             as
             in
             an
             unknown
             way
             cure
             or
             much
             lessen
             this
             or
             that
             determinate
             Disease
             .
             But
             yet
             I
             shall
             now
             apply
             my
             discourse
             peculiarly
             to
             the
             last
             sort
             of
             these
             Medicines
             ,
             as
             being
             both
             more
             considerable
             in
             it self
             and
             the
             chief
             subject
             intended
             in
             present
             Discourse
             ,
             giving
             nevertheless
             ,
             as
             occasion
             serves
             ,
             such
             additional
             Hints
             and
             observations
             ,
             as
             may
             make
             the
             Reflections
             ,
             belonging
             to
             this
             Third
             sort
             of
             Specificks
             ,
             easily
             applicable
             
               Mutatis
               Mutandis
            
             to
             the
             other
             two
             .
          
           
           
             And
             I
             shall
             begin
             with
             laying
             here
             for
             a
             foundation
             what
             I
             have
             in
             another
             Treatise
             had
             occasion
             to
             deliver
             and
             make
             out
             ,
             namely
             ,
             That
             a
             living
             Humane
             Body
             is
             not
             to
             be
             look'd
             upon
             as
             a
             mere
             statue
             ,
             or
             a
             mere
             Congeries
             of
             the
             Materials
             't
             is
             compos'd
             of
             ,
             Flesh
             ,
             Blood
             ,
             Bones
             ,
             Fat
             ,
             Nerves
             ,
             Veins
             ,
             Arteries
             ,
             &c.
             
             But
             an
             admirably
             fram'd
             Engine
             ,
             consisting
             of
             Stable
             ,
             Liquid
             ,
             and
             Pneumatick
             Substances
             ,
             so
             exquisitely
             adapted
             to
             their
             respective
             functions
             and
             Uses
             ,
             that
             oftentimes
             the
             effects
             of
             an
             agent
             upon
             it
             are
             not
             to
             be
             measured
             so
             much
             by
             the
             power
             of
             that
             agent
             considered
             in
             it self
             ,
             as
             by
             the
             effects
             that
             are
             consequently
             produc'd
             by
             the
             action
             of
             the
             parts
             of
             the
             Living
             Engine
             it self
             upon
             one
             another
             .
          
           
             This
             premis'd
             ,
             I
             consider
             ▪
             that
             there
             is
             no
             need
             to
             grant
             that
             the
             operations
             of
             all
             Specificks
             ,
             or
             of
             the
             same
             in
             differing
             Diseases
             ,
             must
             be
             of
             one
             kind
             ;
             but
             that
             differing
             Specificks
             may
             operate
             in
             several
             manners
             ,
             and
             some
             by
             one
             of
             these
             ways
             may
             oppugn
             
             such
             a
             disease
             ,
             and
             others
             may
             do
             good
             against
             such
             another
             .
             And
             of
             these
             general
             ways
             I
             shall
             briefly
             propose
             six
             or
             seven
             that
             now
             occur
             to
             my
             thoughts
             .
             For
             having
             first
             given
             you
             this
             important
             caution
             ,
             that
             the
             Specifick
             Remedy
             do's
             not
             commonly
             (
             though
             sometimes
             it
             may
             )
             relieve
             the
             patient
             by
             this
             or
             that
             single
             way
             of
             operating
             ,
             but
             by
             a
             concurrence
             of
             two
             or
             more
             ,
             that
             as
             it
             were
             joyn
             their
             forces
             to
             produce
             the
             desired
             effect
             .
          
           
             
               PROPOSITION
               .
               I.
               
            
             
               And
               first
               ,
               sometimes
               the
               Specifick
               Medicine
               may
               cure
               by
               discussing
               ,
               or
               resolving
               the
               morbifick
               matter
               ,
               and
               thereby
               making
               it
               fit
               for
               expulsion
               by
               the
               greater
               common
               shores
               of
               the
               Body
               ,
               and
               the
               Pores
               of
               the
               skin
               .
            
             
               'T
               is
               known
               that
               many
               Diseases
               ,
               and
               those
               oftentimes
               stubborn
               and
               Chronical
               ,
               proceed
               from
               certain
               tough
               or
               viscous
               Humours
               ,
               that
               obstruct
               the
               passages
               wereby
               the
               blood
               should
               
               circulate
               ,
               or
               other
               usefull
               Liquors
               be
               transmitted
               .
               And
               these
               peccant
               Humours
               are
               oftentimes
               so
               viscid
               and
               obstinate
               ,
               that
               ordinary
               Remedies
               will
               do
               little
               or
               no
               good
               upon
               them
               .
               And
               yet
               a
               Specifick
               may
               ,
               by
               the
               smalness
               ,
               and
               congruous
               Figure
               of
               some
               of
               its
               Corpuscles
               ,
               get
               through
               the
               Pores
               into
               the
               Recesses
               of
               this
               stubborn
               matter
               ;
               and
               by
               their
               
                 solidity
                 ,
                 Figure
              
               ,
               and
               Agitation
               ,
               promoted
               by
               the
               heat
               of
               the
               patients
               Body
               ,
               may
               dissolve
               and
               ruine
               the
               texture
               of
               the
               Morbifick
               matter
               ,
               and
               render
               it
               capable
               of
               being
               proscribed
               by
               nature
               ,
               by
               Urine
               ,
               Sweat
               ,
               or
               some
               other
               commodious
               and
               innocent
               Evacuation
               .
               Thus
               the
               blood
               ,
               or
               some
               other
               Liquor
               of
               the
               Body
               ,
               being
               (
               to
               use
               the
               Chymists
               Phrase
               )
               impregnated
               with
               the
               friendly
               and
               operative
               Particles
               of
               the
               Remedy
               ,
               becomes
               an
               appropriated
               Menstruum
               in
               referrence
               to
               the
               Pecant
               matter
               :
               impregnated
               with
               Sal
               Armoniack
               becomes
               a
               Menstruum
               ,
               that
               by
               degrees
               will
               dissolve
               both
               Copper
               and
               Iron
               ,
               as
               compact
               bodies
               as
               they
               are
               .
               I
               said
               
                 appropriated
                 Menstruum
              
               ,
               because
               
               there
               is
               no
               sufficient
               reason
               to
               suppose
               ,
               that
               the
               Menstruum
               works
               by
               any
               manifest
               quality
               ,
               as
               Heat
               Moisture
               ,
               &c.
               or
               even
               by
               Acidity
               it self
               :
               But
               rather
               by
               virtue
               of
               the
               fitness
               ,
               which
               the
               shape
               ,
               bulk
               ,
               solidilty
               ,
               and
               other
               Mechanical
               affections
               of
               its
               particles
               ,
               concur
               to
               give
               it
               ,
               to
               disjoyn
               the
               parts
               of
               a
               body
               of
               such
               a
               determinate
               Texture
               .
               For
               as
               I
               have
               in
               another
               Paper
               amply
               shewn
               ,
               there
               are
               far
               more
               Menstruums
               of
               distinct
               sorts
               than
               are
               commonly
               taken
               notice
               of
               ,
               and
               the
               operations
               of
               these
               cannot
               safely
               be
               measured
               by
               the
               strength
               of
               their
               manifest
               qualities
               ,
               since
               it
               may
               several
               times
               happen
               ,
               that
               a
               Menstruum
               ,
               less
               acid
               or
               less
               strongly
               tasted
               ,
               may
               dissolve
               this
               or
               that
               body
               ,
               which
               another
               Menstruum
               ,
               that
               seems
               far
               stronger
               ,
               will
               not
               work
               on
               .
               Thus
               cold
               water
               will
               dissolve
               the
               white
               of
               an
               Egg
               ,
               which
               pure
               spirit
               of
               wine
               will
               be
               so
               far
               from
               dissolving
               ,
               that
               it
               will
               coagulate
               it
               ;
               [
               and
               so
               will
               spirit
               of
               Salt
               and
               Oyl
               of
               Vitriol
               it self
               .
               ]
               Thus
               dephlegm'd
               spirit
               of
               Urine
               
               will
               readily
               dissolve
               minute
               filings
               of
               Copper
               ,
               which
               spirit
               of
               Vinegar
               will
               but
               slowly
               work
               upon
               ;
               and
               yet
               this
               Liquor
               will
               speedily
               dissolve
               Crabs
               Eyes
               ,
               which
               spirit
               of
               Urine
               will
               leave
               entire
               .
               Thus
               Quicksilver
               ,
               that
               is
               insipid
               ,
               will
               in
               the
               cold
               dissolve
               Gold
               ,
               which
               
                 Aqua
                 Fortis
              
               it self
               ,
               though
               assisted
               by
               exeternal
               heat
               will
               not
               work
               upon
               ;
               and
               yet
               
                 Aqua
                 Fortis
              
               will
               furiously
               bear
               asunder
               the
               parts
               of
               Iron
               ,
               though
               Quicksilver
               will
               not
               so
               much
               as
               adhere
               to
               its
               surface
               .
               And
               thus
               in
               fine
               (
               not
               to
               accumulate
               instances
               )
               common
               Oyl
               ,
               that
               is
               so
               smooth
               upon
               the
               Tongue
               ,
               and
               will
               not
               dissolve
               so
               much
               as
               an
               Egg-shell
               ,
               will
               dissolve
               Brimstone
               ,
               which
               yet
               will
               resist
               
                 Aqua
                 Fortis
              
               it self
               ,
               that
               will
               dissolve
               almost
               all
               Metals
               ,
               beside
               many
               hard
               Stones
               and
               Minerals
               .
               And
               I
               know
               a
               liquor
               ,
               having
               more
               than
               once
               prepar'd
               it
               ,
               which
               ,
               though
               so
               weak
               that
               one
               may
               drink
               a
               Wine
               Glass
               full
               of
               it
               pure
               without
               danger
               ,
               will
               yet
               work
               on
               some
               very
               hard
               bodies
               ,
               both
               Stones
               &
               
               Metals
               ,
               in
               a
               way
               that
               is
               not
               to
               be
               matched
               ,
               among
               the
               highly
               corrosive
               Menstruums
               in
               use
               among
               Chymists
               .
            
             
               And
               now
               ,
               supposing
               that
               the
               active
               Corpuscles
               ,
               of
               a
               specifick
               Medicineassociated
               with
               the
               blood
               ,
               or
               other
               Vehicle
               they
               impregnate
               ,
               may
               act
               upon
               the
               morbifick
               matters
               they
               meet
               with
               in
               the
               body
               ,
               after
               the
               manner
               of
               Menstruum
               ;
               supposing
               this
               I
               say
               ,
               we
               may
               hence
               illustrate
               several
               things
               that
               have
               reference
               to
               the
               operation
               of
               specifick
               Medicines
               .
            
             
               1.
               
               And
               we
               may
               hence
               derive
               a
               Guess
               ,
               why
               an
               appropriated
               Medicine
               will
               perform
               things
               ,
               which
               will
               not
               be
               done
               by
               another
               ,
               whose
               manifest
               qualities
               seem
               to
               be
               the
               same
               for
               kind
               ,
               and
               much
               stronger
               in
               degree
               .
               For
               Menstruums
               do
               not
               always
               act
               according
               to
               the
               degree
               of
               their
               Acidity
               ,
               or
               the
               like
               sensible
               quality
               ,
               but
               according
               to
               the
               congruity
               of
               their
               Corpuscles
               to
               the
               pores
               of
               the
               body
               they
               are
               to
               dissolve
               ;
               and
               also
               oftentimes
               according
               to
               a
               fitness
               that
               depends
               upon
               other
               Mechanical
               Affections
               
               of
               the
               acting
               Liquor
               .
               And
               therefore
               Physicians
               ,
               as
               well
               as
               others
               ,
               may
               easily
               mistake
               in
               their
               Argumentations
               
                 à
                 majori
                 ad
                 minus
                 ,
                 &
                 à
                 minori
                 ad
                 majus
                 .
              
               For
               the
               consequence
               is
               not
               good
               to
               argue
               either
               thus
               ,
               Water
               ,
               which
               is
               so
               strengthless
               Liquor
               ,
               will
               dissolve
               Gum
               Arabic
               ,
               therefore
               highly
               rectified
               spirit
               of
               Wine
               ,
               which
               is
               a
               much
               more
               subtil
               and
               penetrateing
               Liquor
               ,
               will
               doe
               the
               same
               thing
               more
               powerfully
               ;
               for
               Experience
               shews
               ,
               it
               will
               not
               dissolve
               it
               at
               all
               :
               or
               thus
               ,
               strong
               Oyl
               of
               Vitriol
               is
               more
               corrosive
               in
               taste
               ,
               and
               will
               dissolve
               many
               bodies
               that
               
                 Aqua
                 Fortis
              
               will
               not
               ,
               therefore
               it
               will
               also
               dissolve
               Silver
               as
               well
               as
               
                 Aqua
                 Fortis
              
               ,
               the
               contrary
               of
               which
               is
               true
               .
               Nay
               't
               is
               not
               a
               good
               inference
               to
               argue
               thus
               ,
               
                 Aqua
                 Fortis
              
               is
               dissolves
               Silver
               by
               virtue
               of
               its
               acid
               Spirits
               ,
               therefore
               the
               more
               it
               abounds
               with
               these
               ,
               the
               more
               potently
               it
               will
               dissolve
               that
               Metal
               ,
               whereas
               I
               have
               elsewhere
               prov'd
               by
               Experience
               ,
               that
               if
               
                 Aqua
                 Fortis
              
               be
               made
               exceeding
               strong
               ,
               it
               will
               not
               
               work
               upon
               Silver
               ,
               but
               it
               will
               readily
               do
               it
               if
               it
               be
               weakned
               by
               the
               addition
               of
               a
               fit
               quantity
               of
               Common
               Water
               .
            
             
               To
               this
               I
               shall
               add
               ,
               that
               the
               dissolution
               of
               a
               Body
               may
               depend
               ,
               as
               well
               upon
               the
               peculiar
               texture
               of
               the
               body
               it self
               ,
               as
               the
               manifest
               strength
               of
               the
               Menstruum
               .
            
             
               2ly
               .
               The
               foregoing
               Doctrine
               may
               suggest
               a
               Reason
               ,
               why
               a
               Medicine
               that
               does
               wonders
               in
               one
               disease
               ,
               may
               do
               little
               or
               nothing
               in
               another
               ,
               that
               some
               may
               think
               to
               be
               a
               kin
               to
               it
               ,
               and
               perhaps
               too
               ,
               more
               easily
               superable
               by
               it
               .
               For
               the
               presum'd
               cognation
               may
               not
               be
               so
               great
               ,
               but
               that
               some
               dissimilitude
               of
               texture
               in
               the
               morbifick
               matters
               ,
               may
               make
               one
               of
               them
               unfit
               to
               be
               wrought
               upon
               by
               the
               same
               Menstruum
               that
               dissoloves
               the
               other
               .
               And
               though
               pure
               Spirit
               of
               Wine
               will
               easily
               enough
               dissolve
               
                 Gummi
                 Guajacum
              
               ,
               and
               also
               the
               little
               portion
               of
               resinous
               matter
               that
               are
               harbour'd
               in
               the
               Pores
               and
               small
               cavities
               of
               the
               Wood
               ;
               yet
               the
               same
               Menstruum
               will
               
               not
               work
               upon
               the
               Wood
               it self
               of
               the
               Tree
               that
               affords
               those
               soluble
               Substances
               .
            
             
               3.
               
               This
               may
               keep
               it
               from
               being
               thought
               strange
               ,
               that
               Specifick
               Medicines
               should
               sometimes
               fail
               of
               their
               usual
               Effects
               .
               For
               ,
               as
               the
               Bodies
               of
               individual
               Patients
               ,
               may
               differ
               very
               much
               ,
               either
               according
               to
               their
               natural
               Constitution
               ,
               or
               to
               that
               which
               they
               acquire
               by
               the
               disease
               that
               distempers
               them
               ,
               or
               on
               both
               those
               accounts
               ;
               So
               it
               ought
               not
               to
               seem
               strange
               ,
               that
               in
               some
               sick
               Persons
               among
               many
               ,
               the
               congruity
               between
               the
               agent
               ct
               patient
               should
               be
               alter'd
               ,
               either
               by
               some
               considerable
               change
               in
               the
               Texture
               of
               the
               Morbifick
               matter
               ,
               or
               by
               some
               notable
               alteration
               that
               the
               Corpuscles
               of
               the
               Medicine
               receive
               in
               their
               passage
               through
               the
               Vessels
               ,
               by
               the
               admixture
               of
               some
               incongruous
               Particles
               of
               the
               Blood
               or
               other
               Vehicle
               .
               Thus
               Spirit
               of
               Salt
               will
               ,
               as
               I
               have
               try'd
               ,
               dissolve
               Copper
               ,
               as
               Spirit
               of
               Niter
               does
               :
               which
               notwithstanding
               ,
               thô
               this
               last
               nam'd
               Liquor
               will
               dissolve
               Silver
               ,
               
               yet
               if
               you
               mix
               with
               it
               Spirit
               of
               Salt
               ,
               which
               by
               the
               like
               operation
               of
               both
               upon
               Copper
               ,
               seems
               to
               be
               amicable
               to
               it
               ,
               the
               Spirit
               of
               Niter
               will
               no
               more
               be
               able
               to
               dissolve
               Silver
               ,
               as
               it
               could
               before
               .
            
             
               4thly
               .
               Our
               Hypothesis
               may
               also
               hint
               to
               us
               an
               answer
               to
               one
               of
               the
               main
               and
               most
               plausible
               objections
               of
               the
               deniers
               of
               Specifick
               Medicines
               .
               For
               some
               of
               them
               ask
               in
               a
               Scornful
               way
               ,
               how
               't
               is
               possible
               that
               a
               Medicine
               should
               rove
               up
               and
               down
               in
               the
               Mass
               of
               Blood
               ,
               and
               neglecting
               all
               other
               things
               ,
               should
               single
               out
               ,
               and
               fasten
               upon
               the
               Morbifick
               matter
               men
               wish
               it
               should
               proscribe
               .
               For
               if
               the
               Medicine
               acts
               by
               impregnating
               the
               Blood
               ,
               or
               some
               other
               Liquor
               of
               the
               Body
               ,
               and
               turning
               it
               into
               a
               kind
               of
               Menstruum
               ,
               't
               is
               very
               possible
               ,
               both
               that
               the
               strainers
               through
               which
               the
               Corpuscles
               must
               pass
               ,
               may
               keep
               back
               the
               inconvenient
               parts
               of
               the
               vehicle
               ,
               and
               (
               which
               is
               in
               our
               case
               more
               considerable
               )
               the
               Menstruum
               may
               be
               either
               appropriated
               to
               the
               peccant
               Humour
               ,
               
               as
               has
               been
               formerly
               declar'd
               ,
               or
               else
               may
               at
               least
               be
               qualify'd
               ,
               to
               resolve
               that
               more
               easily
               than
               any
               other
               Substance
               it
               meets
               with
               in
               the
               Body
               .
               As
               if
               you
               take
               some
               Bone-ashes
               ,
               and
               
                 Crocus
                 Martis
              
               ,
               and
               Saw-dust
               ,
               and
               powdered
               Sea-Salt
               ,
               and
               Filings
               of
               Gold
               ,
               and
               blend
               all
               these
               together
               ,
               if
               upon
               one
               half
               of
               this
               mixture
               you
               pour
               common
               Water
               ,
               it
               will
               not
               meddle
               with
               any
               other
               of
               the
               Ingredients
               except
               the
               Sea-Salt
               ,
               which
               it
               will
               readily
               dissolve
               :
               &
               if
               upon
               the
               other
               half
               of
               the
               same
               mixture
               ,
               you
               put
               a
               sufficient
               quantity
               of
               Quick-silver
               ,
               and
               rub
               them
               together
               ,
               this
               Metalline
               Liquor
               will
               neglect
               all
               the
               rest
               of
               the
               Ingredients
               ,
               and
               the
               Sea
               Salt
               it self
               ,
               and
               fasten
               upon
               the
               Gold.
               And
               those
               that
               work
               in
               the
               Spanish
               Gold
               mines
               inform
               us
               ,
               that
               when
               they
               have
               well
               ground
               some
               Ore
               ,
               that
               contains
               Gold
               and
               Copper
               ,
               besides
               Heterogeneous
               Minerals
               ,
               well
               heated
               Quick-silver
               will
               take
               up
               the
               Gold
               much
               sooner
               and
               better
               than
               it
               will
               the
               Copper
               ,
               scarce
               meddling
               with
               the
               latter
               ,
               as
               long
               
               as
               there
               remains
               any
               not
               despicable
               quantity
               of
               the
               former
               ,
               to
               be
               wrought
               upon
               by
               it
               .
               And
               as
               for
               the
               supposed
               difficulty
               ,
               that
               the
               Medicine
               should
               Ferret
               out
               ,
               if
               I
               may
               so
               speak
               ,
               the
               morbifick
               matter
               ,
               in
               what
               vessel
               soever
               of
               the
               Body
               it
               lies
               ,
               this
               objection
               might
               have
               been
               considerable
               ,
               before
               the
               discovery
               of
               the
               Bloods
               circulation
               :
               But
               't
               is
               not
               so
               now
               that
               we
               know
               ,
               that
               things
               that
               once
               get
               into
               the
               Mass
               of
               Blood
               ,
               are
               presently
               whirl'd
               about
               with
               it
               ,
               and
               may
               be
               convey'd
               by
               it
               even
               to
               small
               vessels
               lying
               in
               the
               remotest
               Parts
               of
               the
               Body
               .
            
             
               5thly
               .
               And
               this
               prompts
               me
               to
               take
               notice
               ,
               that
               our
               Hypothesis
               may
               help
               us
               to
               answer
               those
               many
               learned
               Physicians
               ,
               that
               either
               reject
               ,
               or
               at
               least
               despise
               ,
               most
               External
               remedies
               ,
               especially
               
                 Pericarpia
                 ,
                 Amulets
              
               ,
               and
               Appensa
               ,
               upon
               a
               supposition
               ,
               both
               that
               they
               neither
               can
               furnish
               the
               Body
               they
               do
               but
               externally
               touch
               ,
               with
               any
               store
               of
               Medicinal
               Particles
               ;
               and
               which
               is
               chiefly
               in
               this
               place
               to
               be
               
               consider'd
               ,
               that
               being
               but
               external
               remedies
               ,
               they
               must
               be
               very
               unable
               to
               do
               good
               in
               Internal
               diseases
               ,
               especially
               such
               as
               are
               seated
               in
               Parts
               ,
               remote
               from
               those
               which
               the
               Medicine
               is
               apply'd
               to
               .
               But
               as
               to
               the
               former
               part
               of
               the
               objection
               ,
               't
               will
               not
               be
               difficult
               to
               answer
               it
               to
               him
               that
               has
               read
               what
               I
               have
               elsewhere
               written
               of
               the
               subtility
               ,
               numerousness
               and
               efficacy
               of
               Effluviums
               .
               And
               we
               need
               but
               consider
               ,
               what
               plenty
               of
               Particles
               sensible
               to
               the
               nostrils
               ,
               are
               for
               a
               long
               time
               emitted
               by
               a
               small
               quantity
               of
               Amber-greece
               ,
               or
               even
               of
               Camphire
               (
               which
               is
               often
               externally
               us'd
               )
               and
               the
               multitude
               of
               Magnetical
               Corpuscles
               ,
               that
               for
               many
               years
               constantly
               effluviate
               from
               a
               small
               vigorous
               Load-stone
               ,
               to
               think
               it
               possible
               that
               even
               dry
               and
               stable
               Bodies
               may
               afford
               sufficient
               store
               of
               effluvia
               ,
               to
               perform
               considerable
               things
               in
               so
               curiously
               fram'd
               an
               Engine
               ,
               as
               the
               Humane
               Body
               is
               ;
               where
               we
               see
               that
               the
               odour
               of
               Musk
               ,
               or
               Civet
               ,
               for
               instance
               ,
               may
               speedily
               cast
               divers
               Persons
               into
               Fits
               ,
               and
               the
               smell
               
               of
               Castor
               or
               
                 Assa
                 faetida
              
               ,
               and
               much
               more
               that
               of
               Salt
               of
               Harts-horn
               or
               of
               Sal
               Armoniack
               ,
               quickly
               relieve
               them
               .
               And
               as
               to
               the
               Second
               Part
               of
               the
               objection
               ,
               what
               I
               have
               elsewhere
               made
               out
               ,
               and
               the
               best
               Modern
               Physicians
               grant
               ,
               
               of
               the
               Porosity
               of
               the
               Skin
               ,
               shows
               ,
               that
               't
               is
               very
               possible
               for
               the
               subtil
               Effluvia
               of
               several
               Bodies
               ,
               to
               get
               through
               the
               Pores
               of
               the
               Skin
               ;
               and
               when
               they
               have
               once
               got
               admittance
               ,
               so
               much
               as
               into
               the
               smaller
               Vessels
               ,
               't
               is
               easie
               to
               conceive
               how
               these
               may
               carry
               them
               into
               the
               greater
               ,
               and
               consequently
               into
               the
               Mass
               of
               Blood
               ,
               by
               whose
               Circulation
               they
               may
               be
               readily
               conveyed
               to
               all
               the
               Parts
               of
               the
               Body
               ,
               and
               among
               them
               to
               the
               seat
               of
               the
               disease
               :
               &
               perhaps
               ,
               (
               to
               add
               that
               upon
               the
               by
               ,
               )
               the
               efficacy
               of
               these
               Corpuscles
               ,
               that
               ,
               if
               I
               may
               so
               speak
               ,
               get
               in
               at
               the
               Key-hole
               ,
               not
               at
               the
               Door
               ,
               may
               be
               the
               more
               considerable
               ,
               because
               they
               get
               presently
               into
               the
               Mass
               of
               Blood
               ,
               without
               passing
               thrô
               those
               
               Digestions
               in
               the
               stomach
               and
               other
               Parts
               ,
               which
               oftentimes
               much
               weaken
               the
               vertue
               of
               Medicines
               taken
               in
               at
               the
               Mouth
               ,
               before
               they
               arrive
               at
               the
               Blood.
               
            
          
           
             
               PROPOSITION
               .
               II.
               
            
             
               Sometimes
               a
               Specifick
               Medicine
               may
               mortify
               the
               over
               Acid
               ,
               or
               other
               immoderate
               Particles
               that
               infest
               the
               Mass
               of
               Blood
               ,
               and
               destroy
               their
               coagulatory
               or
               other
               effects
               .
            
             
               Thô
               I
               am
               not
               of
               their
               opinion
               ,
               who
               of
               late
               are
               wont
               to
               impute
               almost
               all
               Diseases
               to
               acidity
               ,
               abounding
               in
               the
               Blood
               and
               other
               Liquors
               of
               the
               Body
               ,
               by
               whose
               intervention
               the
               stable
               parts
               also
               are
               offended
               ;
               yet
               I
               readily
               grant
               that
               a
               considerable
               number
               of
               Distempers
               are
               ,
               at
               least
               in
               great
               part
               ,
               produc'd
               either
               by
               Acids
               themselves
               ,
               or
               by
               their
               bad
               effects
               or
               Productions
               .
               Agreeably
               to
               which
               Doctrine
               we
               may
               very
               probably
               conceive
               ,
               that
               several
               Maladies
               may
               be
               either
               quite
               
               cur'd
               ,
               or
               much
               lessen'd
               ,
               by
               a
               Specifick
               Remedy
               that
               abounds
               in
               Corpuscles
               fitted
               to
               mortify
               Acids
               .
               This
               mortification
               may
               be
               effected
               by
               more
               than
               one
               way
               ,
               and
               of
               these
               wayes
               the
               chief
               that
               now
               occur
               to
               my
               thoughts
               ,
               are
               two
               .
            
             
               For
               there
               are
               some
               Bodies
               ,
               that
               mortify
               or
               disable
               Acids
               by
               a
               
                 positive
                 Hostility
              
               ,
               if
               I
               may
               so
               term
               it
               ;
               that
               is
               ,
               by
               such
               a
               contrariety
               as
               is
               discernable
               by
               the
               Tast
               ,
               and
               more
               by
               the
               visible
               conflict
               ,
               and
               manifest
               Tumult
               ,
               that
               is
               produc'd
               ,
               when
               they
               come
               to
               invade
               an
               Acid.
               Of
               this
               sort
               of
               mortifiers
               of
               Acids
               ,
               are
               the
               most
               part
               of
               those
               that
               are
               call'd
               
                 Alcalisate
                 Salts
              
               .
               Whether
               fixt
               ,
               as
               the
               Lixivial
               Salts
               of
               Plants
               ,
               or
               volatile
               ,
               as
               the
               Spirits
               and
               ascending
               Salts
               of
               Urine
               ,
               Blood
               ,
               Harts-horn
               ,
               Soot
               ,
               &c.
               
               As
               may
               be
               exemplify'd
               ,
               when
               any
               of
               these
               comes
               to
               be
               mingled
               with
               
                 Aqua
                 fortis
              
               ,
               Spirit
               of
               Salt
               ,
               Oyl
               of
               Vitriol
               ,
               or
               the
               like
               Acid
               Liquors
               ,
               by
               which
               by
               the
               way
               we
               may
               see
               ,
               that
               those
               Galenists
               mistake
               ,
               who
               ascribe
               the
               vertues
               of
               Spirit
               of
               Harts-horn
               ,
               
               and
               of
               Urine
               ,
               only
               to
               their
               tenuity
               of
               Parts
               ,
               Briskness
               of
               Motion
               ,
               and
               the
               like
               affections
               ,
               that
               they
               might
               not
               seem
               beholding
               to
               the
               Chymists
               for
               so
               useful
               a
               notion
               ,
               as
               that
               of
               the
               contrariety
               of
               Acids
               and
               Alcalies
               .
            
             
               The
               other
               principal
               way
               ,
               by
               which
               Acids
               may
               be
               mortifi'd
               ,
               or
               disabled
               to
               bite
               ,
               is
               by
               Sheathing
               them
               ,
               if
               I
               may
               so
               express
               it
               .
               For
               as
               a
               knife
               may
               be
               disabled
               to
               cut
               ,
               either
               by
               filing
               off
               or
               otherwise
               blunting
               its
               Edge
               ,
               or
               else
               by
               covering
               the
               Blade
               with
               a
               sheath
               fit
               for
               it
               ,
               or
               by
               sticking
               it
               into
               a
               Loaf
               of
               Bread
               ,
               or
               the
               like
               Body
               fit
               to
               receive
               and
               detain
               the
               whole
               Blade
               ;
               so
               an
               Acid
               Corpuscle
               may
               lose
               its
               power
               of
               cutting
               or
               pricking
               ,
               either
               by
               having
               its
               Figure
               spoil'd
               by
               the
               action
               of
               a
               strong
               and
               manifest
               Alcaly
               ,
               or
               else
               by
               being
               as
               it
               were
               sheath'd
               in
               a
               Porous
               Body
               ,
               thô
               perhaps
               endow'd
               with
               no
               Tast
               ,
               or
               any
               other
               manifest
               Quality
               ,
               by
               which
               one
               would
               think
               it
               contrary
               to
               the
               Acid
               it
               disables
               ,
               as
               a
               file
               is
               to
               the
               edge
               of
               a
               knife
               .
               
               Of
               this
               way
               of
               mortifying
               Acids
               ,
               Chymical
               operations
               afford
               us
               many
               instances
               ,
               as
               when
               Menium
               destroyes
               the
               Acidity
               of
               Spirit
               of
               Vinegar
               ,
               as
               I
               have
               found
               Chalk
               will
               do
               that
               of
               
                 Aqua
                 Fortis
              
               it self
               ;
               and
               
                 Lapis
                 Calaminaris
              
               very
               much
               lessens
               ,
               as
               well
               as
               alters
               ,
               the
               Acidity
               of
               Spirit
               of
               Salt
               ,
               and
               even
               of
               Spirit
               of
               Niter
               .
               And
               I
               the
               rather
               mention
               this
               Mineral
               ,
               both
               because
               its
               Qualities
               are
               less
               known
               to
               Physicians
               ,
               and
               the
               generality
               of
               Chymists
               ,
               and
               because
               it
               supplies
               me
               with
               an
               Argument
               to
               prove
               that
               Acids
               may
               be
               ,
               thô
               I
               do
               not
               think
               they
               alwayes
               are
               ,
               rather
               sheath'd
               in
               ,
               than
               destroy'd
               by
               the
               Bodies
               that
               silently
               mortify
               them
               .
               For
               ,
               as
               Glauber
               has
               truly
               enough
               observed
               ,
               Acid
               Spirits
               (
               as
               I
               have
               try'd
               in
               some
               )
               may
               by
               force
               of
               fire
               be
               driven
               in
               Distillation
               out
               of
               the
               
                 Lapis
                 Calaminaris
              
               ,
               very
               much
               dephlegm'd
               ,
               and
               stronger
               than
               before
               .
            
             
               I
               know
               it
               may
               be
               here
               objected
               ,
               that
               the
               Mortification
               of
               Acids
               is
               perform'd
               
               by
               a
               manifest
               Quality
               ,
               and
               therefore
               makes
               nothing
               for
               the
               feavourers
               of
               Specifick
               Medicines
               .
               But
               to
               this
               I
               answer
               .
            
             
               1.
               
               That
               the
               power
               of
               mortifying
               Acids
               ,
               especially
               by
               sheathing
               them
               ,
               or
               if
               you
               please
               ,
               by
               Absorption
               of
               them
               ,
               is
               none
               of
               those
               Qualities
               ,
               whether
               First
               ,
               Second
               or
               Third
               ,
               that
               the
               former
               Physicians
               took
               notice
               of
               in
               Medicines
               ;
               thô
               the
               sufficiency
               of
               these
               Qualities
               to
               cure
               diseases
               ,
               has
               been
               ,
               and
               still
               is
               ,
               us'd
               by
               many
               as
               a
               ground
               of
               denying
               the
               Specifick
               vertues
               of
               remedies
               .
            
             
               2.
               
               That
               I
               have
               often
               look'd
               upon
               it
               as
               an
               happy
               mistake
               ,
               and
               of
               ill
               consequence
               ,
               that
               so
               many
               learned
               modern
               Physicians
               take
               it
               for
               granted
               ,
               that
               if
               a
               Medicine
               be
               endow'd
               with
               a
               manifest
               Quality
               ,
               as
               Acid
               or
               Alcalisate
               ,
               the
               good
               it
               does
               ,
               (
               and
               the
               like
               for
               the
               most
               part
               may
               be
               said
               of
               the
               Harm
               )
               may
               safely
               be
               abscrib'd
               to
               that
               Quality
               ,
               that
               is
               to
               its
               being
               of
               an
               Acid
               ,
               or
               else
               of
               an
               Alcalisate
               nature
               ;
               whereas
               in
               my
               poor
               Judgment
               ,
               there
               
               being
               a
               considerable
               disparity
               ,
               as
               various
               Tryals
               have
               assur'd
               me
               ,
               between
               Acid
               and
               Acid
               ,
               as
               likewise
               between
               Alcaly
               aud
               Alcaly
               ,
               't
               is
               fit
               to
               distinguish
               betwixt
               an
               Acid
               for
               instance
               ,
               as
               meerly
               such
               ,
               and
               the
               peculiar
               modification
               that
               may
               belong
               to
               that
               Acid.
               Thus
               ,
               thô
               all
               Acid
               Menstruums
               that
               I
               know
               of
               ,
               if
               they
               be
               well
               dephlegm'd
               ,
               will
               dissolve
               Copper
               ,
               yet
               
                 Aqua
                 Regis
              
               that
               will
               dissolve
               not
               only
               that
               Metal
               ,
               but
               the
               much
               more
               closely
               compacted
               body
               of
               Gold
               ,
               will
               not
               at
               all
               dissolve
               Silver
               ;
               as
               on
               the
               other
               side
               
                 Aqua
                 Fortis
              
               ,
               as
               corrosive
               a
               Menstruum
               as
               it
               is
               ,
               will
               not
               of
               it self
               dissolve
               Gold
               ,
               but
               if
               you
               give
               it
               a
               new
               Modification
               ,
               by
               adding
               to
               it
               common
               Spirit
               of
               Salt
               ,
               which
               it self
               I
               have
               often
               found
               (
               whatever
               Chymists
               think
               or
               have
               written
               to
               the
               contrary
               )
               will
               leave
               it
               entire
               ,
               the
               
                 Aqua
                 Fortis
              
               will
               easily
               dissolve
               that
               Metal
               .
               Nay
               a
               different
               Modification
               may
               not
               only
               make
               a
               Disparity
               between
               Acid
               ,
               but
               that
               which
               according
               to
               the
               receiv'd
               way
               of
               Judging
               ,
               ought
               to
               be
               call'd
               a
               contrariety
               :
               
               for
               Spirit
               of
               Salt
               will
               precipitate
               Silver
               ,
               which
               
                 Aqua
                 Fortis
              
               has
               dissolv'd
               ,
               and
               Spirit
               of
               Niter
               ,
               thô
               one
               of
               the
               Acidest
               Menstruums
               we
               have
               ,
               will
               not
               only
               precipitate
               an
               Antimonical
               powder
               out
               of
               that
               odd
               substance
               ,
               that
               Chymists
               call
               
                 Butter
                 of
                 Antimony
              
               ,
               but
               will
               do
               it
               with
               a
               wonderful
               conflict
               ,
               tumult
               ,
               and
               effervesence
               ;
               and
               yet
               this
               Butter
               of
               Antimony
               is
               so
               highly
               Acid
               ,
               that
               a
               little
               quantity
               of
               it
               ,
               put
               into
               a
               considerable
               one
               of
               Water
               ,
               makes
               it
               so
               sour
               ,
               that
               many
               Chymists
               call
               it
               
                 Acetum
                 Philosophorum
              
               .
               And
               now
               to
               apply
               these
               things
               to
               the
               lately
               propos'd
               objection
               ,
               I
               desire
               it
               may
               be
               remembred
               ,
               that
               near
               the
               beginning
               of
               this
               Letter
               I
               plainly
               intimated
               to
               you
               ,
               that
               I
               did
               not
               deny
               ,
               but
               that
               a
               Specifick
               Medicine
               may
               sometimes
               be
               accompany'd
               with
               ,
               or
               even
               in
               part
               operate
               by
               a
               manifest
               quality
               ,
               but
               that
               yet
               I
               thought
               the
               good
               effect
               was
               not
               due
               ,
               barely
               to
               the
               kind
               or
               degree
               of
               the
               manifest
               Quality
               ,
               but
               to
               somewhat
               superadded
               which
               gave
               it
               a
               Specifick
               vertue
               ,
               
               against
               this
               or
               that
               particular
               Disease
               .
               And
               suitably
               to
               this
               it
               may
               be
               said
               ,
               that
               ,
               as
               there
               are
               several
               kinds
               of
               Acids
               ,
               and
               of
               Alcalies
               too
               ,
               't
               is
               not
               every
               Acid
               that
               will
               be
               mortifi'd
               by
               every
               Alcaly
               ;
               and
               have
               its
               Effects
               destroy'd
               by
               it
               ,
               which
               may
               be
               illustrated
               by
               this
               ,
               that
               ,
               thô
               when
               Copper
               is
               dissolved
               in
               
                 Aqua
                 Fortis
              
               't
               is
               possible
               ,
               by
               the
               help
               of
               meer
               Chalk
               skilfully
               apply'd
               to
               make
               the
               Menstruum
               let
               go
               the
               Corpuscles
               of
               the
               Metal
               ,
               yet
               if
               upon
               such
               a
               high
               colour'd
               solution
               of
               Copper
               ,
               you
               shall
               pour
               (
               as
               to
               convince
               some
               ingenious
               men
               ,
               I
               have
               purposely
               done
               a
               due
               quantity
               of
               Spirit
               of
               Urine
               ,
               or
               the
               like
               volatile
               Alcaly
               ,
               thô
               there
               will
               presently
               ensue
               a
               great
               conflict
               and
               manifest
               ebullition
               ,
               with
               noise
               and
               store
               of
               Bubbles
               ,
               yet
               between
               these
               Hostile
               Salts
               ,
               a
               multitude
               of
               the
               Acid
               Corpuscles
               of
               the
               
                 Aqua
                 Fortis
              
               will
               not
               be
               so
               mortified
               ,
               as
               to
               let
               go
               the
               Metal
               ,
               but
               the
               solution
               varying
               its
               colour
               ,
               will
               have
               and
               keep
               a
               deeper
               one
               than
               before
               .
            
             
               And
               when
               I
               consider
               the
               differences
               
               that
               a
               Skilful
               Observer
               may
               find
               ,
               between
               Vinegar
               ,
               Alum
               ,
               Crystals
               of
               Tartar
               ,
               Juice
               of
               Lemmons
               ,
               Juice
               of
               Barbaries
               ,
               the
               essential
               Salts
               (
               as
               Chymists
               call
               them
               )
               of
               those
               Plants
               that
               are
               sour
               in
               Tast
               ,
               to
               omit
               divers
               other
               Acids
               ,
               I
               am
               apt
               to
               think
               ,
               that
               disorder'd
               nature
               may
               have
               ,
               in
               a
               diseased
               Body
               ,
               produc'd
               Acids
               of
               several
               sorts
               which
               are
               not
               particularly
               known
               to
               us
               ,
               and
               that
               some
               of
               these
               may
               be
               of
               such
               a
               nature
               ,
               that
               none
               of
               our
               common
               Alcalies
               ,
               as
               such
               ,
               is
               able
               to
               mortify
               them
               ,
               and
               which
               yet
               may
               be
               mortify'd
               ,
               at
               least
               by
               the
               way
               of
               Sheathing
               ,
               by
               some
               appropriated
               or
               peculiarly
               modify'd
               Corpuscles
               of
               a
               Specifick
               Remedy
               which
               may
               be
               illustrated
               by
               what
               is
               elsewhere
               observ'd
               ,
               that
               ,
               thô
               neither
               Spirit
               of
               Vinegar
               ,
               nor
               Spirit
               of
               Salt
               ,
               nor
               Oyl
               of
               Vitriol
               it self
               ,
               would
               ,
               as
               far
               as
               I
               have
               try'd
               ,
               dissolve
               a
               stone
               taken
               out
               of
               a
               mans
               Body
               ,
               yet
               Spirit
               of
               Niter
               ,
               (
               which
               does
               not
               dissolve
               several
               Podies
               ,
               that
               I
               have
               found
               dissoluble
               in
               Oyl
               of
               Vitriol
               )
               
               will
               readily
               work
               upon
               it
               ,
               and
               thereby
               lose
               ,
               its
               Corrosiveness
               .
            
             
               Before
               I
               leave
               this
               Subject
               ,
               't
               will
               not
               be
               amiss
               to
               intimare
               a
               couple
               of
               things
               ,
               that
               perhaps
               you
               will
               not
               think
               impertinent
               to
               it
               .
            
             
               One
               of
               these
               is
               ,
               that
               ,
               whereas
               I
               not
               long
               ago
               distinctly
               nam'd
               Acids
               themselves
               and
               their
               Productions
               ,
               I
               did
               it
               (
               not
               out
               of
               Inadvertence
               ,
               but
               )
               because
               I
               think
               Preternatural
               Acids
               do
               not
               only
               disaffect
               the
               Body
               whilest
               they
               continue
               sensibly
               Acid
               ,
               but
               may
               in
               divers
               cases
               be
               the
               causes
               of
               some
               Distempers
               ,
               whereof
               most
               men
               would
               think
               them
               more
               likely
               to
               be
               the
               remedies
               .
               For
               ,
               thô
               Acids
               be
               reputed
               to
               have
               an
               Incisive
               and
               Resolutive
               vertue
               ,
               and
               therefore
               Oxymel
               and
               some
               other
               Acetous
               Medicines
               are
               commended
               to
               cut
               tough
               Phlegm
               ,
               and
               Spirit
               of
               Vitriol
               is
               us'd
               for
               the
               same
               purpose
               ,
               and
               to
               dissolve
               coagulated
               Blood
               ;
               Yet
               ,
               as
               I
               am
               willing
               to
               grant
               this
               vertue
               unto
               Acids
               in
               some
               cases
               ,
               so
               there
               are
               others
               wherein
               I
               much
               
               suspect
               ,
               that
               obstructions
               ,
               and
               consequently
               the
               diseases
               that
               usually
               attend
               obstinate
               ones
               ,
               may
               be
               occasion'd
               by
               Acids
               ,
               as
               they
               coagulate
               some
               Fluids
               in
               the
               Mass
               of
               Blood
               ,
               that
               are
               dispos'd
               to
               be
               thicken'd
               by
               them
               ,
               and
               by
               that
               consistence
               made
               unfit
               to
               pass
               with
               the
               rest
               of
               the
               circulating
               Blood
               ,
               through
               the
               smaller
               Vessels
               and
               strainers
               of
               the
               Body
               ,
               where
               upon
               that
               account
               they
               make
               obstructions
               .
               This
               I
               shall
               exemplify
               by
               the
               coagulation
               that
               I
               have
               made
               by
               some
               Acid
               Salts
               ,
               as
               Spirit
               of
               Salt
               ,
               of
               the
               White
               of
               an
               Egg
               ,
               especially
               if
               by
               beating
               reduc'd
               to
               an
               Aqueous
               Consistence
               .
               And
               the
               like
               coagulation
               may
               easily
               be
               effected
               in
               Milk
               ,
               which
               may
               not
               only
               be
               speedily
               curdl'd
               with
               Spirit
               of
               Salt
               ,
               but
               ,
               as
               is
               known
               by
               Bodies
               not
               Chymically
               prepar'd
               ,
               as
               Rennet
               and
               Juice
               of
               Lemons
               .
               And
               Experiments
               purposely
               made
               have
               shown
               ,
               that
               ,
               if
               some
               Acids
               be
               convey'd
               immediately
               into
               the
               Mass
               of
               Blood
               ,
               they
               will
               coagulate
               even
               that
               Liquor
               ,
               whilst
               it
               continues
               
               in
               the
               Vessels
               of
               the
               yet
               living
               Animals
               .
            
             
               The
               other
               thing
               I
               lately
               told
               you
               ,
               I
               was
               to
               observe
               ,
               is
               ,
               that
               ,
               thô
               Acid
               Corpuscles
               are
               those
               ,
               that
               modern
               Physicians
               and
               Chymists
               are
               wont
               to
               take
               notice
               of
               as
               hurtful
               ,
               both
               in
               the
               Blood
               and
               stable
               Parts
               of
               the
               Body
               ,
               except
               the
               Stomach
               ,
               and
               perhaps
               some
               few
               neighbouring
               Parts
               ,
               as
               the
               Spleen
               and
               Pancres
               .
               And
               ,
               thô
               some
               ingenious
               men
               proceed
               so
               far
               ,
               as
               to
               impute
               almost
               all
               Diseases
               to
               the
               bad
               Effects
               of
               Acids
               ,
               yet
               I
               am
               very
               inclinable
               to
               think
               ,
               that
               divers
               maladies
               and
               ttoublesom
               Symptoms
               proceed
               from
               Corpuscles
               ,
               that
               ,
               whether
               they
               be
               of
               a
               Saline
               nature
               or
               not
               ,
               are
               different
               from
               Acids
               properly
               so
               call'd
               .
               For
               I
               consider
               ,
               that
               there
               may
               be
               many
               Bodie
               ,
               which
               may
               as
               't
               were
               result
               from
               the
               combination
               of
               Acids
               with
               other
               Saline
               Particles
               ,
               that
               much
               alter
               their
               nature
               ,
               as
               I
               have
               elsewhere
               noted
               ,
               that
               Spirit
               of
               Salt
               will
               ,
               with
               Spirit
               of
               Urine
               ,
               compose
               a
               kind
               of
               Sal-Armoniac
               ;
               and
               Spirit
               of
               Niter
               with
               Salt
               of
               
               Tartar
               dissolv'd
               in
               common
               Water
               ,
               will
               concoagulate
               with
               it
               into
               Salt
               Petre
               (
               or
               a
               Body
               exceeding
               like
               it
               ,
               )
               and
               the
               same
               Spirit
               of
               Niter
               or
               
                 Aqua
                 Fortis
              
               with
               Spirit
               of
               Urine
               ,
               or
               of
               Blood
               ,
               or
               the
               like
               ,
               will
               afford
               a
               very
               fusible
               Salt
               ,
               differing
               enough
               from
               what
               either
               of
               the
               Ingredients
               was
               before
               their
               conjunction
               .
               And
               't
               is
               vulgarly
               known
               ,
               that
               Oyl
               of
               Vitriol
               ,
               and
               Oyl
               of
               Tartar
               
                 per
                 deliquium
              
               ,
               do
               by
               their
               coalition
               produce
               
                 Tartarum
                 Vitriolatum
              
               ,
               in
               which
               the
               Acidity
               of
               the
               former
               ,
               and
               the
               Alcalisateness
               of
               the
               latter
               ,
               are
               very
               much
               infring'd
               ,
               a
               third
               Body
               being
               by
               resultancy
               produc'd
               ,
               that
               differs
               much
               both
               from
               the
               former
               and
               the
               latter
               Oyl
               ,
               or
               rather
               
                 Saline
                 Liquor
              
               .
               And
               when
               ,
               besides
               Instances
               of
               this
               nature
               ,
               I
               consider
               how
               many
               differing
               sorts
               of
               Corpuscles
               so
               fruitful
               a
               Principle
               as
               nature
               may
               have
               form'd
               ,
               that
               ,
               without
               being
               Acid
               ,
               may
               yet
               have
               notable
               and
               hurtful
               Effects
               upon
               the
               Blood
               ,
               or
               some
               particular
               solid
               part
               of
               the
               Body
               .
               It
               seems
               probable
               to
               me
               ,
               that
               there
               
               may
               be
               other
               Qualities
               requir'd
               ,
               to
               mortify
               or
               disable
               these
               Morbifick
               Corpuscles
               ,
               than
               a
               contrariety
               to
               Acid
               Salts
               ,
               and
               consequently
               ,
               that
               a
               Medicine
               that
               affords
               Corpuscles
               peculiarly
               fitted
               to
               correct
               or
               enervate
               this
               particular
               sort
               of
               hurtful
               ones
               ,
               may
               deserve
               the
               name
               of
               a
               Specifick
               .
            
             
               And
               here
               I
               further
               consider
               ,
               that
               ,
               as
               in
               the
               Body
               there
               may
               be
               divers
               coagulations
               made
               by
               Saline
               Corpuscles
               manifestly
               Acid
               ;
               so
               there
               may
               be
               others
               produc'd
               by
               Corpuscles
               ,
               Whether
               Saline
               in
               tast
               or
               no
               ,
               that
               are
               not
               manifestly
               Acid
               ,
               but
               perhaps
               rather
               of
               a
               contrary
               nature
               ,
               which
               observation
               ,
               being
               wont
               to
               be
               overlook'd
               by
               Physicians
               ,
               and
               yet
               in
               my
               opinion
               of
               no
               small
               importance
               ,
               may
               deserve
               to
               be
               a
               little
               the
               more
               carefully
               made
               out
               .
               I
               have
               sometimes
               for
               curiosity
               made
               a
               Liquor
               ,
               that
               was
               not
               in
               Tast
               either
               Acid
               or
               Urinous
               ;
               to
               which
               having
               put
               a
               moderate
               proportion
               of
               a
               distill'd
               Liquor
               ,
               which
               it self
               was
               not
               in
               tast
               either
               
               Acid
               ,
               or
               Urinous
               ,
               or
               lixiviate
               ,
               it
               would
               in
               a
               very
               short
               time
               ,
               perhaps
               in
               not
               many
               minutes
               ,
               be
               coagulated
               into
               so
               consistent
               a
               Body
               ,
               that
               ,
               thô
               the
               wide
               mouth'd
               Vessel
               were
               held
               with
               the
               Orifice
               downwards
               ,
               nothing
               would
               fall
               out
               of
               it
               .
            
             
               I
               have
               taught
               in
               another
               (
               unpublish'd
               Paper
               ,
               that
               if
               upon
               a
               certain
               solution
               (
               which
               I
               there
               show
               how
               to
               make
               )
               one
               drop
               some
               Spirit
               of
               Urine
               ,
               or
               anorhet
               Volatile
               Alcaly
               ,
               there
               will
               presently
               be
               produc'd
               a
               Gelly
               ,
               whose
               consistence
               and
               colour
               may
               make
               it
               easily
               be
               taken
               for
               common
               Starch
               ,
               ready
               to
               be
               imploy'd
               to
               stiffen
               Linnen
               .
            
             
               The
               like
               Gelly
               ,
               but
               more
               transparent
               ,
               I
               have
               more
               than
               once
               made
               ,
               without
               the
               help
               of
               any
               thing
               ,
               that
               is
               sensibly
               Acid
               or
               Urinous
               .
            
             
               I
               have
               also
               ,
               to
               convince
               some
               virtuosi
               ,
               showed
               them
               somewhat
               to
               their
               surprise
               ,
               a
               substance
               I
               had
               prepar'd
               without
               the
               help
               of
               Urine
               ,
               or
               any
               volatile
               Alcaly
               ,
               (
               and
               sometimes
               
               almost
               in
               a
               trice
               )
               that
               would
               in
               very
               few
               minutes
               coagulate
               above
               twice
               ,
               if
               not
               thrice
               its
               weight
               of
               highly
               rectify'd
               and
               inflamable
               vinous
               Spirit
               into
               a
               stable
               Mass
               .
            
             
               And
               to
               shew
               you
               ,
               that
               't
               is
               not
               requisite
               that
               a
               Liquor
               be
               strongly
               ,
               or
               so
               much
               as
               sensibly
               Acid
               ,
               to
               coagulate
               an
               Animal
               Substance
               ,
               as
               I
               lately
               noted
               ,
               that
               the
               Spirit
               of
               Salt
               did
               the
               White
               of
               an
               egg
               ,
               I
               shall
               add
               ,
               that
               well
               dephlegm'd
               Spirit
               of
               Wine
               will
               do
               the
               same
               thing
               as
               well
               ,
               if
               not
               better
               .
            
          
           
             
               PROPOSITION
               III.
               
            
             
               Sometimes
               the
               Specifick
               Medicine
               may
               help
               the
               Patient
               ,
               by
               precipitating
               the
               Peccant
               matter
               out
               of
               the
               Blood
               ,
               or
               other
               Liquor
               (
               of
               the
               Body
               )
               that
               harbours
               it
               .
            
             
               Thô
               Precipitation
               be
               oftentimes
               a
               consequent
               of
               the
               Mortification
               of
               Acids
               ,
               or
               of
               Alcalies
               ,
               by
               Corpuscles
               
               of
               a
               contrary
               Quality
               ,
               yet
               I
               thought
               fit
               to
               say
               something
               of
               it
               apart
               :
               Because
               I
               have
               observed
               that
               some
               Acids
               and
               Alcalies
               may
               be
               put
               together
               without
               causing
               Precipitation
               by
               their
               contrariety
               ;
               and
               on
               the
               other
               side
               ,
               that
               divers
               Precipitations
               may
               be
               produc'd
               where
               there
               do's
               not
               appear
               any
               Hostility
               ,
               though
               I
               know
               divers
               ingenious
               men
               ,
               who
               think
               this
               Effect
               it self
               a
               sufficient
               Argument
               ,
               that
               the
               hostility
               of
               Acids
               and
               Alcalies
               must
               be
               the
               cause
               of
               it
               .
               But
               that
               should
               not
               be
               taken
               for
               granted
               ,
               but
               prov'd
               by
               collateral
               Experiments
               ,
               that
               do
               not
               suppose
               the
               Truth
               of
               the
               Hypothesis
               it self
               .
               But
               to
               proceed
               to
               our
               Exampls
               ,
               I
               know
               (
               and
               elsewhere
               mention
               )
               several
               Urinous
               Spirits
               ,
               that
               I
               could
               mix
               with
               Acid
               Menstruum
               without
               making
               any
               manifest
               Conflict
               ,
               or
               Precipitation
               ;
               And
               on
               the
               otherside
               ,
               Acids
               and
               Alcalies
               ,
               that
               will
               make
               a
               manifest
               Conflict
               by
               their
               mutual
               creation
               ,
               and
               yet
               if
               they
               be
               mingled
               in
               a
               just
               proportion
               ,
               will
               have
               for
               the
               consequent
               of
               their
               
               Mixture
               ,
               Coalition
               instead
               of
               Precipitation
               ;
               as
               may
               be
               exemplified
               in
               certain
               Mixtures
               of
               Spirit
               of
               Sal-Armoniac
               (
               made
               with
               Salt
               of
               Tartar
               ,
               or
               Pot-Ashes
               )
               and
               Spirit
               of
               Nitre
               or
               
                 Aqua
                 Fortis
              
               ;
               and
               also
               when
               Spirit
               of
               Urine
               and
               Spirit
               of
               Salt
               ,
               being
               mingled
               in
               a
               certain
               proportion
               ,
               convene
               into
               Corpuscles
               for
               the
               making
               of
               Sal-Armoniac
               ,
               which
               the
               Phlegm
               of
               those
               Liquors
               will
               keep
               swimming
               .
               But
               that
               which
               makes
               most
               for
               my
               present
               purpose
               ,
               is
               ,
               that
               there
               may
               be
               Precipitations
               ,
               where
               ,
               whatever
               may
               be
               suppos'd
               ,
               it
               does
               not
               appear
               that
               there
               is
               any
               Tumult
               or
               Contrariety
               ,
               as
               when
               Silver
               being
               dissolved
               in
               
                 Aqua
                 Fortis
              
               ,
               and
               the
               Menstruum
               diluted
               with
               30
               or
               40
               parts
               of
               distill'd
               Water
               ,
               or
               of
               Rain
               Water
               ,
               if
               clean
               Plates
               of
               Copper
               be
               immers'd
               in
               the
               Solution
               ,
               the
               Metal
               will
               be
               very
               slowly
               Precipitated
               out
               of
               it
               ,
               in
               the
               form
               not
               of
               a
               Calx
               ,
               consisting
               of
               Metalline
               ,
               and
               Saline
               Parts
               incorporated
               together
               ,
               but
               ,
               at
               least
               at
               the
               beginning
               in
               the
               form
               of
               pure
               shineing
               
               Scales
               of
               Silver
               ,
               almost
               like
               the
               white
               and
               glittering
               Scales
               of
               some
               smal
               Fishes
               .
               There
               is
               also
               a
               way
               ,
               by
               which
               I
               have
               brought
               dissolv'd
               Gold
               to
               settle
               about
               a
               Body
               ,
               suspended
               in
               the
               Solution
               ,
               in
               the
               form
               of
               a
               fine
               and
               high-colour'd
               Calx
               of
               pure
               Gold.
               But
               you
               may
               easily
               see
               an
               Instance
               of
               silent
               Precipitation
               ,
               if
               you
               do
               but
               rub
               a
               little
               either
               Roman
               or
               Dantzick
               Vitriol
               ,
               upon
               the
               well
               whetted
               blade
               of
               a
               knife
               wetted
               with
               Water
               or
               Spittle
               ,
               for
               you
               will
               have
               the
               Steel
               ,
               almost
               in
               a
               trice
               ,
               overlaid
               with
               a
               reddish
               substance
               ,
               which
               by
               its
               colour
               and
               other
               signs
               appears
               manifestly
               to
               be
               Cupreous
               .
               And
               here
               I
               shall
               advertise
               you
               ,
               that
               't
               is
               not
               only
               ,
               as
               is
               wont
               to
               be
               suppos'd
               ,
               out
               of
               Solutions
               made
               with
               Acids
               ,
               that
               bodies
               may
               be
               thus
               Precipitated
               ,
               for
               upon
               search
               I
               have
               found
               that
               there
               are
               in
               nature
               Precipitants
               ,
               that
               are
               capable
               of
               silently
               Precipitating
               some
               Bodies
               dissolv'd
               in
               Urinous
               Menstruums
               ,
               or
               others
               not
               Acid
               .
               I
               know
               it
               may
               be
               suspected
               ,
               and
               that
               not
               without
               colour
               of
               Reason
               ,
               
               that
               such
               Precipitations
               may
               be
               dangerous
               ,
               by
               producing
               Heterogeneous
               Corpuscles
               in
               the
               Blood
               ,
               that
               may
               be
               too-heavy
               or
               gross
               to
               be
               evacuated
               .
               And
               I
               look
               upon
               this
               as
               a
               suspicion
               ,
               for
               whose
               Resolution
               't
               were
               fit
               to
               consult
               Experience
               .
               But
               in
               the
               mean
               time
               one
               may
               represent
               .
            
             
               1.
               
               That
               ,
               thô
               some
               Inconvenience
               may
               happen
               from
               the
               Bulk
               of
               the
               precipitated
               Corpuscles
               ,
               yet
               that
               may
               be
               much
               inferiour
               to
               the
               danger
               threatned
               by
               the
               over-active
               &
               hostile
               Particles
               ,
               that
               produc'd
               or
               fomented
               the
               disease
               .
            
             
               2.
               
               That
               ,
               't
               is
               not
               necessary
               that
               all
               concretions
               should
               consist
               of
               Corpuscles
               so
               bulky
               ,
               as
               to
               be
               too
               big
               to
               be
               thrown
               out
               of
               the
               Mass
               of
               Blood
               ,
               for
               we
               see
               that
               stony
               matter
               ,
               which
               ,
               as
               the
               Chymical
               Analysis
               of
               it
               shews
               ,
               is
               of
               a
               very
               compounded
               nature
               ,
               may
               be
               carryed
               to
               all
               Parts
               of
               the
               Body
               .
               And
               I
               remember
               I
               knew
               a
               Lady
               ,
               who
               a
               while
               before
               she
               told
               me
               the
               Story
               ,
               had
               a
               stone
               taken
               out
               of
               the
               lower
               
               part
               of
               her
               Tongue
               .
               And
               Physicians
               ,
               that
               prescribe
               great
               quantities
               of
               Mineral
               Waters
               impregnated
               with
               Iron
               ,
               such
               as
               I
               found
               those
               of
               Tunbridge
               to
               be
               ,
               and
               with
               Sulphur
               ,
               such
               as
               some
               of
               the
               Bath
               Waters
               are
               ,
               are
               wont
               to
               build
               their
               expectations
               of
               Curing
               with
               them
               ,
               upon
               a
               supposition
               ,
               that
               they
               are
               carryed
               into
               the
               Mass
               of
               Blood
               ,
               and
               consequently
               to
               the
               innermost
               parts
               of
               the
               Body
               .
            
             
               3.
               
               That
               yet
               't
               is
               possible
               ,
               Precipitations
               may
               be
               made
               of
               matters
               contain'd
               in
               the
               Blood
               ,
               by
               Medicines
               that
               do
               not
               get
               into
               the
               Mass
               of
               it
               .
               As
               Physicians
               give
               Steel
               in
               Substance
               sometimes
               crude
               ,
               as
               well
               as
               oftentimes
               prepar'd
               ,
               to
               mortify
               the
               Acidities
               of
               the
               Blood
               ,
               though
               the
               Metalline
               Corpuscles
               do
               not
               ,
               for
               ought
               we
               know
               ,
               pass
               into
               the
               Mass
               of
               it
               ,
               but
               are
               wrought
               upon
               by
               the
               matter
               ,
               that
               in
               its
               circulation
               is
               thrown
               out
               of
               it
               into
               the
               Stomach
               &
               Guts
               ,
               where
               their
               operation
               on
               it
               is
               probably
               inferr'd
               from
               the
               blackness
               ,
               that
               Chalybeates
               are
               wont
               give
               the
               excrements
               
               of
               the
               lower
               Belly
               ;
               and
               if
               they
               will
               have
               it
               ,
               that
               prepar'd
               Steel
               ,
               for
               instance
               ,
               calcin'd
               with
               Sulphur
               ,
               gets
               through
               the
               Pores
               of
               the
               Bowels
               ,
               or
               the
               extremities
               of
               the
               capillary
               Vessels
               ,
               into
               the
               Mass
               of
               Blood
               it self
               ,
               't
               will
               be
               obvious
               to
               demand
               ,
               why
               nature
               should
               not
               be
               able
               to
               expel
               Precipitate
               Corpuscles
               at
               the
               same
               passages
               ,
               at
               which
               such
               compounded
               Concretions
               ,
               as
               those
               of
               Sulphur
               and
               Metal
               ,
               can
               get
               in
               .
            
             
               4.
               
               That
               some
               may
               very
               speciously
               pretend
               ;
               that
               Experience
               has
               been
               already
               consulted
               about
               the
               expediency
               of
               imploying
               Precipitating
               Medicines
               .
               For
               not
               to
               urge
               ,
               that
               the
               learned
               and
               judicious
               Sennertus
               seems
               to
               intimate
               ,
               that
               in
               some
               cases
               the
               Fibrile
               Matter
               may
               be
               surmounted
               by
               being
               Precipitated
               out
               of
               the
               Blood
               ;
               there
               is
               a
               Professor
               of
               Physick
               ,
               who
               ,
               thô
               I
               cannot
               assent
               to
               some
               of
               his
               Principles
               &
               Doctrines
               ,
               has
               deliver'd
               several
               considerable
               things
               about
               Fermentation
               and
               Feavers
               :
               &
               this
               Professor
               ,
               by
               name
               Kergerus
               ,
               very
               solemnly
               
               declares
               *
               ,
               that
               for
               fourteen
               years
               he
               cur'd
               above
               a
               thousand
               Febricitants
               without
               bleeding
               ,
               purging
               ,
               or
               sweating
               Medicines
               ,
               (
               to
               which
               he
               adds
               some
               others
               sorts
               )
               by
               a
               single
               precipitating
               Remedy
               .
               I
               endeavour'd
               to
               obtain
               from
               Germany
               an
               account
               of
               the
               truth
               of
               the
               matter
               of
               fact
               ,
               but
               did
               not
               receive
               it
               ;
               only
               I
               found
               that
               a
               Physician
               of
               this
               Emperours
               ,
               does
               ,
               in
               a
               lately
               publish'd
               Book
               ,
               declare
               himself
               inclin'd
               to
               believe
               it
               to
               be
               true
               .
            
             
               I
               shall
               much
               the
               more
               easily
               be
               induc'd
               to
               think
               ,
               that
               great
               and
               desireable
               changes
               may
               be
               wrought
               
               in
               the
               fluid
               Parts
               of
               the
               Body
               by
               appropriated
               Precipitants
               ,
               if
               that
               be
               true
               which
               is
               unanimously
               taught
               by
               a
               multitude
               of
               Physicians
               ,
               who
               impute
               many
               Diseases
               to
               the
               Putrefaction
               of
               the
               Blood
               and
               other
               Liquors
               of
               the
               Body
               .
               For
               ,
               tho
               certain
               Reasons
               oblige
               me
               to
               desire
               you
               ,
               not
               to
               ask
               me
               any
               Questions
               about
               the
               Remedy
               I
               am
               going
               to
               speak
               of
               ,
               because
               I
               must
               not
               yet
               Answer
               them
               ;
               yet
               I
               am
               willing
               you
               should
               on
               this
               occasion
               know
               Historically
               ,
               (
               what
               probably
               you
               will
               think
               strange
               )
               that
               there
               is
               in
               
                 rerum
                 natura
              
               ,
               a
               certain
               Substance
               ,
               which
               is
               so
               powerful
               an
               Enemy
               to
               Putrefaction
               ,
               that
               ,
               when
               a
               few
               grains
               or
               drops
               of
               it
               were
               put
               into
               a
               considerable
               quantity
               of
               Water
               ,
               that
               had
               been
               kept
               till
               it
               stunk
               so
               strongly
               and
               offensively
               ,
               that
               ,
               if
               I
               had
               not
               known
               what
               it
               was
               ,
               I
               should
               have
               judg'd
               the
               smell
               to
               have
               proceeded
               from
               Carrion
               .
               This
               Medicinal
               Liquor
               ,
               I
               say
               ,
               (
               for
               so
               I
               may
               call
               it
               ,
               )
               being
               diffus'd
               by
               agitation
               through
               this
               abominably
               stinking
               Water
               ,
               (
               which
               did
               not
               
               appear
               turbid
               to
               the
               Eye
               )
               in
               so
               very
               small
               a
               proportion
               ,
               Precipitated
               out
               of
               it
               a
               very
               little
               and
               light
               Feculency
               ,
               which
               being
               separated
               ,
               the
               rest
               of
               the
               Liquor
               was
               quite
               freed
               from
               all
               stink
               ;
               nor
               did
               I
               observe
               that
               the
               Feculency
               it self
               had
               any
               .
               And
               ,
               which
               is
               very
               notable
               ,
               all
               this
               was
               done
               in
               a
               very
               few
               minutes
               ,
               by
               a
               Precipitant
               ,
               whose
               Tast
               was
               not
               at
               all
               either
               Bitter
               ,
               or
               Acid
               ,
               or
               Urinous
               ,
               or
               Lixivial
               .
               All
               which
               are
               Circumstances
               ,
               that
               may
               afford
               good
               Hints
               to
               speculative
               and
               sagacious
               Inquirers
               .
            
          
           
             
               PROPOSITION
               IV.
               
            
             
               Sometimes
               the
               Specifick
               Remedy
               may
               work
               ,
               by
               peculiarly
               strenthening
               ,
               and
               cherishing
               the
               Heart
               ,
               and
               by
               that
               means
               ,
               or
               without
               it
               ,
               the
               Part
               affected
               .
            
             
               This
               Observation
               can
               scarce
               be
               made
               good
               ,
               without
               entring
               into
               the
               Controversy
               ,
               which
               for
               its
               difficulty
               and
               importance
               ,
               has
               perplex'd
               divers
               Modern
               Physicians
               ;
               whether
               there
               
               be
               any
               Medicines
               ,
               that
               have
               a
               Sympathy
               with
               the
               Head
               ,
               Heart
               ,
               Liver
               &c
               and
               thereby
               deserve
               the
               name
               of
               
                 Cephalic
                 ,
                 Cordial
              
               ,
               or
               
                 Hepatic
                 &c.
              
               
               Or
               ,
               to
               speak
               somewhat
               more
               clearly
               ,
               whether
               there
               be
               any
               Medicines
               ,
               that
               in
               a
               peculiar
               manner
               do
               good
               to
               this
               or
               that
               particular
               internal
               part
               of
               the
               Body
               .
               In
               this
               dispute
               the
               Affirmative
               part
               has
               been
               held
               ,
               but
               I
               doubt
               upon
               slender
               grounds
               of
               reason
               ,
               in
               most
               of
               the
               Physick
               Schools
               for
               several
               Ages
               .
               But
               in
               our
               times
               ,
               many
               do
               not
               only
               maintain
               the
               Negative
               ,
               but
               deride
               the
               Opinion
               they
               have
               forsaken
               .
               For
               some
               of
               them
               object
               in
               a
               Triumphant
               Style
               ,
               that
               t
               is
               ridiculous
               to
               fancy
               such
               a
               Sympathy
               ,
               betwixt
               a
               dead
               Medicine
               ,
               and
               the
               Parts
               of
               a
               living
               body
               .
               As
               that
               the
               Physician
               may
               send
               the
               Drug
               ,
               as
               't
               were
               of
               an
               Errand
               ,
               to
               find
               out
               one
               in
               the
               dark
               ,
               among
               a
               multitude
               of
               others
               ,
               and
               do
               it
               good
               offices
               .
            
             
               But
               notwithstanding
               this
               ,
               I
               think
               it
               very
               possible
               ,
               that
               a
               Medicine
               may
               so
               far
               respect
               a
               particular
               Part
               ,
               as
               ,
               though
               not
               to
               be
               beneficial
               to
               that
               
               only
               ,
               yet
               to
               be
               friendly
               to
               that
               ,
               in
               a
               peculiar
               manner
               or
               degree
               .
               And
               this
               I
               conceive
               it
               may
               be
               ,
               upon
               one
               or
               more
               of
               the
               Accounts
               ,
               that
               I
               shall
               briefly
               mention
               .
            
             
               And
               First
               ,
               when
               I
               consider
               that
               the
               stable
               Parts
               of
               the
               Body
               ,
               as
               the
               Heart
               ,
               Brain
               ,
               Liver
               ,
               Kidneys
               &c.
               have
               each
               its
               particular
               structure
               ,
               wherein
               it
               differs
               from
               others
               ,
               and
               probably
               the
               fluid
               Parts
               also
               ,
               as
               Blood
               ,
               Gall
               ,
               Lympha
               &c.
               have
               their
               distinct
               Textures
               ,
               it
               seems
               not
               improbable
               to
               me
               ,
               that
               the
               Corpuscles
               of
               a
               Medicine
               dissolv'd
               in
               the
               Stomach
               ,
               and
               carryed
               too
               and
               fro
               by
               the
               Liquors
               of
               the
               Body
               ,
               may
               according
               to
               the
               determinate
               shape
               ,
               size
               ,
               stiffness
               or
               flexility
               ,
               motion
               ,
               &c.
               be
               much
               more
               fit
               to
               be
               detain'd
               by
               one
               part
               of
               the
               Body
               ,
               as
               the
               Brain
               ,
               the
               Heart
               &c.
               than
               by
               the
               rest
               ;
               and
               so
               ,
               by
               lodging
               it self
               in
               its
               Pores
               ,
               or
               associating
               with
               its
               Fibres
               ,
               may
               supply
               it
               with
               such
               congruous
               Particle
               ,
               as
               it
               either
               does
               want
               ,
               or
               in
               case
               it
               do
               not
               ,
               may
               by
               their
               congruity
               be
               of
               advantage
               to
               
               it
               ,
               by
               re-establishing
               or
               strengthening
               the
               Tone
               of
               it
               .
               And
               by
               this
               Corroboration
               ,
               the
               Part
               may
               be
               made
               able
               to
               resist
               the
               Hostilities
               of
               Morbifick
               Matters
               ,
               which
               Physicians
               usually
               observe
               to
               be
               wont
               ,
               by
               the
               more
               Vigorous
               Parts
               ,
               to
               be
               thrown
               upon
               the
               Weakned
               or
               Distemper'd
               ones
               ;
               as
               is
               manifest
               in
               persons
               that
               are
               much
               subject
               to
               the
               Gout
               ,
               in
               whom
               oftentimes
               peccant
               humors
               are
               very
               apt
               ,
               upon
               several
               occasions
               ,
               to
               be
               thrown
               off
               by
               the
               nobler
               Parts
               ,
               if
               they
               be
               robust
               ,
               upon
               the
               frequently
               debilitated
               Joints
               ;
               on
               which
               score
               the
               Gout
               ,
               if
               it
               be
               well
               managed
               ,
               is
               ,
               not
               irrationally
               ,
               wont
               to
               be
               thought
               conducive
               to
               long
               life
               .
               And
               on
               this
               occasion
               I
               remember
               ,
               that
               I
               formerly
               knew
               a
               Learned
               Physician
               ,
               who
               ,
               though
               a
               great
               Traveller
               ,
               and
               ,
               as
               such
               ,
               accustom'd
               to
               great
               varieties
               in
               point
               of
               Diet
               ,
               had
               such
               a
               peculiar
               indisposition
               in
               his
               Jaw
               ,
               that
               though
               he
               could
               moderately
               drink
               Wines
               of
               several
               sorts
               without
               inconvenience
               ,
               yet
               the
               drinking
               even
               of
               a
               very
               little
               Brandy
               ,
               would
               
               soon
               after
               give
               him
               the
               Tooth
               Ach
               ,
               of
               which
               odd
               distemper
               he
               has
               sometimes
               complain'd
               to
               me
               .
               But
               this
               upon
               the
               by
               :
               For
               I
               must
               now
               proceed
               to
               illustrate
               and
               make
               probable
               ,
               what
               I
               was
               saying
               of
               the
               possible
               fitness
               of
               some
               Medicinal
               Corpuscles
               ,
               to
               associate
               themselves
               with
               those
               of
               the
               Part
               they
               are
               to
               befriend
               ,
               by
               observing
               what
               happens
               in
               Nutrition
               ,
               especially
               in
               that
               of
               sucking-children
               .
               For
               in
               these
               ,
               one
               single
               Aliment
               ,
               namely
               Milk
               ,
               does
               afford
               ,
               besides
               various
               excrements
               ,
               such
               as
               the
               grosser
               faeces
               of
               the
               Guts
               ,
               and
               the
               more
               fluid
               ones
               of
               the
               Bladder
               ,
               the
               Mouth
               ,
               the
               Nose
               ,
               the
               pores
               of
               the
               Skin
               &c.
               a
               great
               number
               of
               Corpuscles
               ,
               that
               are
               not
               only
               detain'd
               ,
               but
               assimilated
               by
               Parts
               of
               differing
               Structures
               ,
               as
               the
               Brain
               ,
               the
               Heart
               ,
               the
               Bones
               &c.
               since
               otherwise
               these
               parts
               could
               never
               be
               so
               plentifully
               nourished
               by
               them
               ,
               as
               dayly
               to
               increase
               in
               all
               their
               Dimensions
               .
               And
               t
               is
               considerable
               ,
               that
               some
               Parts
               ,
               which
               in
               Babes
               are
               Cartilaginous
               ,
               do
               in
               process
               of
               time
               become
               Boney
               ,
               
               which
               change
               seems
               not
               probably
               referable
               to
               the
               bare
               exsiccation
               ,
               produc'd
               by
               Native
               heat
               ,
               increasing
               with
               the
               Persons
               Age.
               
            
             
               Secondly
               ,
               the
               friendly
               Corpuscles
               of
               a
               Specifick
               Medicine
               ,
               may
               not
               only
               confirm
               the
               good
               estate
               of
               a
               determinate
               Part
               ,
               but
               ,
               which
               makes
               most
               for
               our
               present
               purpose
               ,
               they
               may
               very
               much
               conduce
               to
               restore
               it
               to
               a
               sound
               condition
               ,
               when
               it
               is
               distempered
               ,
               and
               this
               they
               may
               do
               upon
               two
               or
               three
               Accounts
               .
            
             
               For
               in
               the
               first
               place
               ,
               those
               friendly
               Particles
               may
               dispose
               the
               Obstructing
               or
               other
               Morbifick
               matter
               ,
               to
               be
               more
               easily
               and
               safely
               expell'd
               .
               And
               this
               they
               may
               do
               ,
               not
               barely
               as
               they
               impregnate
               the
               whole
               Mass
               of
               Blood
               ,
               and
               so
               may
               be
               carried
               by
               it
               ,
               as
               well
               to
               many
               other
               Parts
               ,
               as
               to
               that
               we
               now
               consider
               ;
               but
               as
               by
               their
               particular
               Texture
               ,
               Motion
               &c.
               they
               may
               in
               a
               peculiar
               manner
               respect
               that
               peculiar
               Modification
               ,
               which
               the
               Peccant
               matter
               may
               have
               acquir'd
               by
               being
               produc'd
               or
               harbour'd
               in
               that
               
               determinate
               part
               :
               And
               that
               the
               distinct
               Structure
               of
               an
               affected
               Part
               may
               much
               diversifie
               the
               condition
               of
               a
               Morbifick
               matter
               ,
               I
               argue
               from
               this
               ,
               among
               other
               things
               ,
               that
               Physicians
               are
               wont
               to
               teach
               (
               though
               I
               have
               found
               the
               Observation
               rather
               to
               hold
               commonly
               than
               unreservedly
               )
               that
               in
               those
               that
               are
               subject
               to
               this
               Stone
               ,
               the
               Petrescent
               matter
               ,
               when
               it
               is
               bred
               in
               the
               Kidneys
               is
               reddish
               or
               yellowish
               ,
               but
               when
               in
               the
               Bladder
               ,
               white
               ,
               or
               of
               a
               light
               gray
               ;
               and
               that
               the
               Stones
               that
               are
               generated
               in
               the
               first
               nam'd
               Parts
               ,
               are
               more
               friable
               ,
               or
               at
               least
               of
               a
               slighter
               Texture
               ,
               than
               those
               that
               have
               their
               Original
               in
               the
               Bladder
               ,
               some
               of
               which
               are
               exceeding
               hard
               ,
               especially
               in
               comparison
               of
               large
               ones
               ,
               that
               I
               have
               had
               out
               of
               the
               Bladder
               or
               Gall
               of
               lusty
               Animals
               .
               The
               aptness
               then
               that
               the
               Corpuscles
               of
               the
               Specifick
               may
               give
               the
               Blood
               ,
               or
               other
               Liquor
               that
               conveys
               them
               ,
               to
               act
               as
               an
               appropriated
               Menstruum
               ,
               upon
               the
               peculiarly
               modified
               Matter
               that
               obstructs
               ,
               or
               otherwise
               disaffects
               ,
               
               the
               Liver
               ,
               for
               Instance
               ,
               may
               enable
               the
               Remedy
               ,
               to
               be
               very
               helpful
               to
               that
               Part
               ,
               by
               preparing
               the
               molesting
               Matter
               for
               expulsion
               .
               But
               it
               may
               also
               succour
               the
               same
               Part
               in
               another
               way
               .
            
             
               For
               in
               the
               second
               place
               ,
               it
               may
               so
               work
               upon
               the
               Fibres
               ,
               and
               stable
               portion
               of
               the
               Part
               affected
               ,
               as
               both
               to
               enable
               it
               ,
               and
               excite
               it
               to
               free
               its
               self
               from
               its
               Enemy
               .
               For
               it
               may
               give
               firmness
               and
               strength
               to
               the
               Fibres
               of
               the
               part
               ;
               it
               may
               also
               contemperate
               ,
               or
               correct
               the
               immoderate
               heat
               ,
               coldness
               &c.
               of
               it
               :
               It
               may
               mortify
               the
               Acid
               ,
               or
               other
               incongruous
               Particles
               ,
               that
               are
               lodg'd
               in
               the
               minute
               Intervals
               of
               the
               stable
               Parts
               ,
               end
               perhaps
               ,
               even
               in
               the
               Pores
               of
               the
               Fibres
               :
               It
               may
               appease
               its
               Convulsions
               ,
               Cramps
               ,
               or
               other
               inordinate
               motions
               ,
               that
               hinder
               it
               from
               daily
               executing
               its
               proper
               Functions
               ;
               it
               may
               relax
               or
               widen
               the
               Pores
               ,
               according
               to
               the
               exigency
               of
               the
               work
               to
               be
               perform'd
               .
               And
               having
               thus
               ,
               by
               means
               of
               its
               friendly
               Corpuscles
               ,
               prepar'd
               the
               
               matter
               to
               be
               expell'd
               ,
               and
               disposed
               the
               part
               to
               expell
               it
               ,
               it
               may
               then
               also
               excite
               the
               Part
               to
               do
               its
               office
               ,
               by
               irritating
               the
               Fibres
               ,
               or
               motive
               Organs
               ,
               or
               stimulating
               them
               to
               disburthen
               the
               Part
               of
               the
               Matter
               that
               offends
               it
               ,
               as
               a
               very
               small
               Dose
               of
               Cantharides
               is
               known
               by
               this
               way
               of
               irritation
               ,
               to
               be
               capable
               of
               making
               the
               Bladder
               forcibly
               ,
               though
               not
               safely
               ,
               discharge
               it self
               of
               Urine
               ,
               and
               with
               that
               oftentimes
               expel
               the
               Sand
               and
               Gravel
               ,
               or
               lesser
               Stones
               ,
               and
               the
               Excrementitious
               Slime
               that
               molested
               it
               before
               .
            
             
               And
               this
               Instance
               may
               be
               of
               use
               to
               us
               ,
               in
               answering
               that
               which
               we
               formerly
               noted
               to
               be
               so
               confidently
               urged
               by
               the
               Rejecters
               of
               Specifick
               Medicines
               .
               For
               here
               we
               have
               a
               Medicine
               ,
               though
               a
               dangerous
               one
               ,
               whose
               Corpuscles
               have
               such
               a
               peculiar
               reference
               to
               the
               Bladder
               ,
               and
               Urinary
               Organs
               ,
               that
               though
               being
               gotten
               into
               the
               Mass
               of
               Blood
               ,
               they
               are
               carried
               by
               it
               indiscriminately
               to
               other
               parts
               of
               the
               Body
               ,
               as
               well
               as
               to
               these
               ;
               yet
               
               oftentimes
               ,
               without
               manifestly
               disaffecting
               the
               rest
               ,
               they
               exceedingly
               irritate
               the
               Bladder
               ,
               and
               determine
               it
               to
               the
               excretion
               of
               what
               it
               contains
               .
               And
               whereas
               it
               may
               be
               objected
               ,
               that
               the
               first
               of
               the
               three
               ways
               ,
               by
               which
               we
               noted
               ,
               that
               a
               particular
               Part
               may
               be
               succour'd
               by
               a
               Specifick
               ,
               seems
               contrary
               to
               the
               second
               ;
               the
               former
               tending
               to
               corroborate
               the
               Part
               ,
               and
               the
               later
               to
               relax
               and
               irritate
               it
               :
               I
               answer
               two
               things
               ,
               one
               ,
               that
               since
               the
               Part
               may
               be
               sometimes
               in
               a
               Natural
               ,
               and
               sometimes
               in
               a
               Preternatural
               state
               ,
               in
               the
               former
               ,
               a
               Medicine
               may
               deserve
               the
               name
               of
               Friendly
               or
               Appropriated
               ,
               because
               it
               keeps
               it
               sound
               ,
               which
               is
               most
               properly
               done
               by
               strengthening
               it
               ;
               and
               in
               the
               later
               it
               may
               merit
               the
               Title
               of
               a
               Specifick
               ,
               because
               it
               helps
               to
               restore
               it
               to
               a
               state
               of
               soundness
               :
               And
               the
               other
               ,
               that
               though
               to
               effect
               this
               Recovery
               ,
               't
               is
               often
               very
               expedient
               ,
               if
               not
               necessary
               ,
               that
               the
               Medicine
               procure
               an
               Evacuation
               of
               some
               matter
               that
               offends
               it
               ;
               yet
               that
               Evacuation
               
               itself
               is
               often
               much
               promoted
               and
               facilitated
               ,
               by
               stengthening
               the
               Part
               so
               ,
               as
               to
               enable
               it
               to
               disburthen
               it self
               .
               And
               the
               same
               Medicine
               may
               contain
               ,
               and
               communicate
               to
               the
               Blood
               ,
               Corpuscles
               of
               such
               differing
               shapes
               ,
               sizes
               ,
               motions
               &c.
               as
               may
               at
               least
               successively
               relieve
               the
               Part
               by
               both
               these
               ways
               ;
               as
               Physicians
               observe
               that
               Rhubarb
               does
               ,
               not
               only
               by
               its
               finer
               and
               Laxative
               Parts
               ,
               purge
               the
               Liver
               of
               Choler
               ,
               but
               by
               its
               more
               earthy
               Astringent
               Corpuscles
               strengthen
               the
               Tone
               of
               that
               Part
               :
               [
               What
               farther
               belongs
               to
               the
               Illustration
               of
               this
               matter
               will
               be
               met
               with
               in
               due
               place
               .
               ]
               On
               this
               occasion
               ,
               't
               will
               not
               be
               impertinent
               to
               add
               ,
               that
               in
               some
               cases
               ,
               this
               very
               Corroboration
               of
               a
               Distempered
               Part
               ,
               may
               restore
               it
               to
               soundness
               ;
               there
               being
               some
               Diseases
               of
               such
               a
               nature
               ,
               that
               they
               are
               ,
               if
               I
               may
               so
               speak
               ,
               almost
               always
               in
               Fieri
               ,
               that
               is
               ,
               they
               could
               not
               continue
               to
               subsist
               in
               the
               affected
               Part
               ,
               unless
               through
               its
               debility
               ,
               and
               the
               consequences
               of
               it
               ,
               it
               were
               subject
               to
               admit
               from
               
               time
               to
               time
               fresh
               recruits
               of
               peccant
               matter
               ,
               to
               foment
               the
               Malady
               :
               And
               in
               such
               Distempers
               ,
               if
               the
               Structure
               and
               Tone
               of
               the
               Part
               be
               re-established
               by
               the
               operation
               of
               the
               Specifick
               Medicine
               ,
               it
               s
               acquir'd
               vigour
               will
               enable
               it
               to
               resist
               the
               Ingress
               of
               new
               supplies
               of
               peccant
               Matter
               ,
               and
               to
               turn
               them
               off
               into
               the
               Mass
               of
               Blood
               ,
               to
               be
               thence
               discharg'd
               by
               the
               Common
               Shores
               of
               the
               Body
               ;
               whilst
               in
               the
               mean
               time
               Nature
               will
               be
               able
               by
               degrees
               to
               subdue
               ,
               dissipate
               ,
               or
               otherwise
               dispose
               of
               ,
               that
               comparatively
               little
               Portion
               of
               peccant
               Matter
               ,
               that
               was
               lodg'd
               in
               the
               Diseas'd
               Part.
               
            
             
               We
               have
               not
               in
               this
               Paper
               given
               any
               Example
               of
               the
               peculiar
               respect
               of
               a
               Specifick
               Medicine
               to
               a
               determinate
               disaffected
               Part
               ,
               that
               one
               would
               think
               so
               incredible
               ,
               as
               that
               a
               heavy
               stony
               substance
               ,
               being
               in
               no
               great
               quantity
               taken
               in
               at
               die
               Mouth
               ,
               should
               manifestly
               contribute
               to
               the
               Cure
               of
               a
               broken
               Bone
               in
               one
               of
               the
               Limbs
               ,
               as
               the
               Leg
               or
               the
               Hands
               .
               And
               yet
               ,
               not
               to
               urge
               the
               Testimony
               of
               
               Chymical
               Writers
               ,
               I
               remember
               a
               German
               Physician
               ,
               that
               was
               Famous
               for
               notable
               Cures
               ,
               related
               Wonders
               to
               me
               of
               the
               efficacy
               of
               that
               Stone
               growing
               in
               his
               Country
               ,
               which
               from
               its
               effect
               they
               call
               Osteocolla
               ,
               especially
               if
               it
               be
               improv'd
               by
               a
               Skilful
               Preparation
               ,
               which
               he
               communicated
               to
               me
               ,
               but
               I
               had
               not
               opportunity
               to
               make
               Tryal
               of
               it
               .
               But
               without
               Preparation
               ,
               the
               judicious
               and
               long
               experienc'd
               Chirurgeon
               
                 Fabricius
                 Hildanus
              
               much
               commends
               upon
               his
               own
               Observation
               a
               single
               Dram
               of
               it
               finely
               Powder'd
               ,
               for
               the
               breeding
               of
               a
               Callus
               to
               soder
               together
               the
               Parts
               of
               a
               broken
               Bone
               :
               Insomuch
               that
               he
               gives
               a
               caution
               to
               use
               it
               but
               sparingly
               in
               young
               and
               vigorous
               Patients
               ,
               lest
               it
               breed
               too
               great
               a
               Callus
               ,
               of
               which
               he
               gives
               a
               notable
               Instance
               .
               And
               the
               like
               caution
               was
               inculcated
               to
               me
               from
               Experience
               ,
               by
               the
               lately
               mention'd
               German
               Doctor
               ,
               because
               otherwise
               (
               he
               said
               )
               his
               Preparation
               would
               in
               such
               Persons
               make
               the
               Medicine
               generate
               a
               Callus
               too
               soon
               and
               too
               great
               .
            
          
           
             
             
               PROPOSITION
               V.
               
            
             
               Sometimes
               a
               Specifick
               Medicine
               may
               do
               its
               work
               ,
               by
               producing
               in
               the
               Mass
               of
               Blood
               ,
               such
               a
               disposition
               ,
               as
               may
               enable
               Nature
               ,
               by
               correcting
               ,
               expelling
               or
               other
               fit
               waies
               ,
               to
               surmount
               the
               morbifick
               Matter
               ,
               or
               other
               Cause
               of
               the
               Disease
               .
            
             
               He
               that
               shall
               heedfully
               observe
               the
               practise
               of
               divers
               Learned
               and
               succesful
               modern
               Physitians
               ,
               may
               discern
               that
               many
               ,
               if
               not
               most
               ,
               of
               their
               Prescriptions
               are
               founded
               upon
               a
               supposition
               ,
               that
               a
               great
               Part
               of
               the
               Diseases
               incident
               to
               Mans
               Body
               ,
               and
               the
               recovery
               from
               them
               ,
               depends
               mainly
               upon
               the
               vitiated
               Constitution
               of
               the
               Blood
               ,
               and
               the
               restoring
               it
               to
               a
               sound
               Condition
               .
            
             
               This
               advantageous
               change
               of
               the
               Blood
               may
               be
               effected
               by
               a
               Specifick
               ,
               several
               waies
               ,
               (
               sometimes
               separately
               ,
               and
               sometimes
               jointly
               ,
               )
               and
               particularly
               by
               those
               that
               follow
               .
            
             
             
               1.
               
               That
               which
               I
               shall
               first
               name
               ,
               is
               ,
               by
               furnishing
               the
               Blood
               with
               some
               sort
               of
               active
               Corpuscles
               ,
               that
               it
               needs
               to
               ferment
               it
               ,
               or
               excite
               
                 an
                 useful
                 Commotion
                 or
                 Agitation
              
               in
               it
               .
            
             
               I
               will
               not
               here
               examine
               ,
               whether
               the
               Mass
               of
               Blood
               ,
               contain'd
               within
               the
               Vessels
               of
               a
               living
               man
               ,
               is
               capable
               of
               a
               Fermentation
               properly
               and
               strictly
               so
               call'd
               ;
               and
               therefore
               I
               employ'd
               also
               the
               word
               Commotion
               ,
               which
               will
               be
               easily
               admitted
               ,
               if
               the
               other
               be
               disliked
               .
               But
               in
               regard
               Fermentation
               is
               a
               Term
               that
               hath
               generally
               obtain'd
               ,
               I
               shall
               not
               scruple
               to
               make
               use
               of
               it
               ,
               after
               what
               I
               have
               intimated
               about
               it
               .
            
             
               But
               because
               many
               modern
               Physitians
               ,
               especially
               since
               the
               Learned
               Willis's
               Notions
               came
               to
               be
               in
               request
               ,
               have
               looked
               upon
               Feavers
               and
               Agues
               to
               consist
               in
               ,
               or
               be
               produc'd
               by
               vitious
               Fermentations
               of
               the
               Blood
               ;
               I
               thought
               fit
               to
               add
               to
               the
               Fermentation
               I
               am
               about
               to
               speak
               of
               ,
               the
               distinguishing
               Epithets
               of
               useful
               .
            
             
             
               This
               premis'd
               ,
               it
               seems
               not
               improbable
               to
               me
               ,
               that
               ,
               as
               there
               is
               oftentimes
               a
               vitious
               Fermentation
               of
               the
               Blood
               ,
               so
               there
               may
               be
               sometimes
               a
               want
               of
               Fermentation
               ,
               or
               a
               certain
               Sluggishness
               ,
               upon
               whose
               account
               ,
               either
               the
               brisk
               intestine
               Agitation
               ,
               that
               it
               ought
               to
               have
               as
               a
               warm
               Fluid
               of
               such
               a
               Nature
               as
               't
               is
               wont
               to
               be
               in
               sound
               Persons
               ,
               or
               a
               due
               quickness
               of
               Circulation
               through
               the
               Heart
               is
               wanting
               :
               To
               which
               Sluggish
               State
               of
               the
               Blood
               ,
               if
               it
               be
               obstinate
               and
               lasting
               ▪
               several
               Distempers
               are
               wont
               to
               be
               consequent
               .
               Now
               ,
               although
               there
               be
               divers
               Medicines
               ,
               such
               as
               Spices
               ,
               Brandy
               ,
               and
               other
               Spirituous
               Liquors
               distill'd
               from
               fermented
               vegetables
               ,
               that
               are
               usually
               ,
               and
               oftentimes
               succesfully
               enough
               ,
               employ'd
               to
               correct
               this
               dull
               Indisposition
               of
               the
               Blood
               ;
               Yet
               in
               regard
               they
               are
               wont
               to
               be
               very
               hot
               ,
               being
               usually
               pitch'd
               upon
               by
               those
               that
               prescribe
               them
               because
               they
               are
               so
               ;
               there
               are
               several
               constitutions
               of
               
               Patients
               ,
               and
               divers
               other
               Circumstances
               ,
               wherein
               they
               are
               not
               safe
               ,
               but
               may
               do
               more
               harm
               by
               their
               immoderate
               Heat
               ,
               than
               good
               by
               their
               Spirituosity
               ,
               Besides
               ,
               that
               the
               Sluggishness
               of
               the
               Blood
               may
               sometimes
               proceed
               from
               Causes
               ,
               that
               this
               sort
               of
               hot
               Medicines
               will
               not
               correct
               .
               I
               remember
               ,
               that
               having
               for
               Tryals
               sake
               moderately
               dry'd
               a
               parcel
               of
               Human
               Blood
               ,
               a
               
                 Vinous
                 Spirit
              
               Total
               inflammable
               would
               not
               ,
               at
               least
               in
               many
               hours
               that
               my
               Experiment
               lasted
               ,
               make
               a
               Solution
               of
               it
               ,
               or
               draw
               a
               red
               Tincture
               from
               it
               ,
               though
               it
               were
               well
               pulveris'd
               :
               Whereas
               a
               well
               rectified
               
                 Vrinous
                 Spirit
              
               grew
               red
               upon
               it
               in
               less
               than
               the
               tenth
               ,
               or
               perhaps
               the
               twentieth
               ,
               part
               of
               that
               Time.
               
            
             
               Now
               a
               Specifick
               Medicine
               may
               abound
               in
               Corpuscles
               of
               such
               a
               Nature
               ,
               that
               without
               dangerously
               ,
               or
               incommodiously
               heating
               the
               Blood
               ,
               they
               may
               disable
               those
               Corpuscles
               ,
               they
               meet
               with
               in
               the
               Blood
               ,
               that
               make
               that
               Liquor
               viscous
               ,
               or
               roapy
               ,
               or
               dispirited
               ;
               
               and
               also
               by
               enlivening
               the
               Mass
               of
               Blood
               ,
               if
               I
               may
               so
               speak
               ,
               or
               puting
               it
               into
               a
               more
               brisk
               and
               kindly
               Agitation
               ,
               may
               make
               it
               fit
               to
               throw
               off
               those
               Heterogeneous
               Parts
               ,
               or
               recrements
               ,
               that
               were
               blended
               with
               it
               before
               ,
               and
               to
               permeate
               ,
               as
               freely
               as
               it
               ought
               ,
               the
               Viscera
               ,
               whose
               Capillary
               Vessels
               and
               Pores
               would
               formerly
               scarce
               ,
               and
               but
               very
               sparingingly
               ,
               admit
               it
               .
            
             
               That
               a
               Specifick
               may
               perform
               this
               ,
               you
               will
               perhaps
               the
               more
               easily
               allow
               ,
               if
               you
               consider
               ,
               that
               the
               generality
               of
               Physitians
               teach
               ,
               that
               there
               are
               several
               Cordials
               ,
               which
               they
               style
               some
               of
               them
               Temperate
               ,
               and
               divers
               of
               them
               Cold
               ,
               (
               as
               in
               effect
               't
               is
               not
               usually
               observ'd
               ,
               that
               they
               considerably
               ,
               if
               at
               all
               sensibly
               ,
               heat
               the
               Body
               ;
               )
               as
               Pearls
               ,
               and
               some
               of
               them
               ,
               being
               gratefully
               Acid
               ,
               should
               rather
               cool
               it
               ,
               as
               Wood-sorrel
               (
               Alleluja
               )
               and
               Goats-Rue
               (
               Galega
               .
               )
               And
               't
               is
               very
               possible
               ,
               that
               the
               Corpuscles
               ,
               that
               make
               the
               Blood
               thick
               ,
               and
               Sluggish
               ,
               may
               not
               be
               of
               a
               Cold
               Nature
               ,
               but
               of
               
               a
               Hot
               ,
               and
               therefore
               may
               have
               their
               Effects
               rather
               befriended
               than
               destroy'd
               by
               divers
               Hot
               Remedies
               :
               As
               ,
               if
               the
               white
               of
               an
               Egg
               be
               by
               beating
               reduc'd
               to
               Water
               ,
               (
               which
               is
               not
               necessary
               to
               the
               Experiment
               ,
               but
               shews
               it
               better
               )
               if
               you
               put
               to
               it
               a
               certain
               Proportion
               of
               well
               dephlegm'd
               Spirit
               of
               Wine
               ,
               instead
               of
               destroying
               the
               viscosity
               of
               the
               Liquor
               ,
               it
               will
               curdle
               a
               good
               part
               of
               it
               ,
               and
               thereby
               produce
               a
               Body
               far
               more
               remote
               from
               Thinness
               and
               Fluidity
               .
            
             
               And
               I
               remember
               ,
               I
               once
               for
               Tryal
               sake
               made
               a
               vegetable
               Liquor
               ,
               which
               ,
               from
               somewhat
               Sluggish
               that
               it
               was
               before
               ,
               did
               presently
               by
               the
               Addition
               of
               a
               little
               Spirit
               of
               Wine
               ,
               grow
               surprisingly
               viscous
               ,
               and
               roapy
               .
            
             
               2.
               
               Another
               way
               ,
               by
               which
               a
               Specifick
               may
               befriend
               the
               Mass
               of
               Blood
               ,
               is
               ,
               by
               imparting
               to
               it
               a
               dilatation
               or
               tenuity
               that
               it
               wants
               .
               This
               Second
               way
               is
               of
               much
               affinity
               to
               the
               First
               ,
               but
               yet
               is
               not
               the
               same
               :
               Because
               in
               that
               ,
               the
               thing
               mainly
               considered
               was
               ,
               the
               Fermentation
               or
               Agitation
               
               of
               the
               Blood
               ;
               Whereas
               this
               mainly
               respects
               the
               Consistence
               of
               it
               ,
               which
               is
               a
               thing
               of
               no
               mean
               importance
               to
               health
               .
               For
               if
               the
               Blood
               be
               too
               thick
               ,
               as
               oftentimes
               it
               is
               ,
               it
               cannot
               pass
               so
               freely
               and
               readily
               ,
               as
               it
               ought
               ,
               through
               the
               Capillary
               Vessels
               ,
               which
               thereby
               come
               to
               be
               by
               little
               and
               little
               obstructed
               ,
               and
               the
               Circulation
               inconveniently
               retarded
               ;
               Whence
               't
               is
               easy
               to
               foresee
               ,
               that
               divers
               mischiefs
               must
               in
               time
               arise
               .
               And
               on
               the
               other
               side
               ,
               if
               the
               Blood
               be
               too
               thin
               ,
               especially
               if
               it
               be
               over
               much
               agitated
               too
               ,
               t
               is
               apt
               to
               make
               its
               way
               out
               of
               the
               Vessels
               ,
               and
               produce
               Hemorrhagies
               ,
               in
               case
               it
               flow
               out
               of
               the
               Body
               ,
               or
               other
               bad
               Effects
               that
               usually
               attend
               the
               Extravasation
               of
               the
               Blood.
               Which
               Liquor
               ,
               when
               it
               is
               out
               of
               its
               proper
               Vessels
               ,
               in
               so
               warm
               a
               place
               as
               a
               Living
               Human
               Body
               ,
               is
               very
               Subject
               to
               Putrefaction
               ,
               and
               thereby
               apt
               to
               produce
               Imposthumes
               and
               several
               mischievous
               Symptoms
               .
            
             
               Now
               a
               Specifick
               Medicine
               may
               remedy
               this
               faulty
               Consistence
               of
               the
               
               Blood
               ,
               by
               furnishing
               it
               with
               Corpuscles
               ,
               fitted
               by
               their
               figure
               ,
               bulk
               ,
               motion
               ,
               &c.
               to
               disable
               those
               peccant
               ones
               that
               make
               the
               Blood
               gross
               ,
               or
               else
               to
               cut
               ,
               or
               divide
               the
               Parts
               of
               the
               Blood
               it self
               ,
               and
               so
               dispose
               them
               to
               be
               more
               fluid
               :
               Or
               else
               they
               may
               produce
               in
               it
               such
               Pores
               ,
               as
               may
               ,
               as
               it
               were
               invite
               the
               subtil
               Aetherial
               matter
               ,
               that
               abounds
               in
               the
               Atmosphaere
               ,
               to
               insinuate
               it self
               into
               the
               Mass
               of
               Blood
               ,
               and
               rarifie
               it
               .
               And
               on
               the
               other
               side
               ,
               when
               the
               Blood
               is
               too
               thin
               ,
               as
               not
               only
               some
               Diseases
               ,
               but
               some
               Medicines
               ,
               especially
               Aloes
               ,
               are
               wont
               to
               make
               it
               ;
               A
               Specifick
               Remedy
               may
               reduce
               it
               to
               a
               good
               Consistence
               ,
               either
               ,
               by
               furnishing
               it
               with
               Corpuscles
               ,
               apt
               to
               Combine
               themselves
               with
               the
               active
               ones
               ,
               that
               did
               too
               much
               Attenuate
               the
               Blood
               ;
               Or
               ,
               by
               helping
               Nature
               to
               expel
               those
               over-busy
               Particles
               ,
               by
               insensible
               Transpiration
               ,
               or
               some
               other
               undisturbing
               way
               .
            
             
               3
               :
               There
               is
               yet
               another
               way
               ,
               by
               which
               a
               Specifick
               Remedy
               may
               conduce
               
               to
               rectifie
               the
               State
               of
               the
               Blood
               And
               that
               is
               ,
               by
               so
               working
               on
               the
               Heart
               ,
               as
               to
               make
               it
               advantageously
               regulate
               the
               Transmission
               of
               that
               Liquor
               through
               it
               .
            
             
               That
               a
               Specifick
               Medicine
               may
               peculiarly
               befriend
               this
               or
               that
               particular
               Part
               ,
               and
               consequently
               the
               Heart
               ,
               is
               granted
               by
               the
               Generality
               of
               Physitians
               ,
               who
               are
               wont
               to
               reckon
               up
               many
               Cordials
               ,
               (
               of
               which
               yet
               I
               fear
               ,
               but
               few
               deserve
               that
               name
               .
               )
               But
               ,
               since
               't
               is
               elsewhere
               in
               this
               Paper
               shewn
               ,
               that
               some
               Medicines
               may
               particularly
               respect
               a
               determinate
               Part
               of
               the
               Body
               ,
               and
               consequently
               the
               Heart
               ;
               One
               may
               be
               allowed
               to
               suppose
               ,
               that
               the
               Corpuscles
               of
               a
               Specifick
               may
               either
               dissolve
               some
               Particles
               they
               meet
               with
               in
               the
               Heart
               ,
               by
               which
               that
               Noble
               Viscus
               is
               by
               Irritation
               ,
               or
               otherwise
               disturb'd
               in
               the
               Regularity
               of
               its
               Dilatations
               ,
               and
               Contractions
               ;
               Or
               ,
               so
               Corroborate
               the
               Fibres
               ,
               or
               Motive
               Organs
               of
               it
               ,
               as
               to
               dispose
               it
               to
               moderate
               the
               Circulation
               of
               the
               Blood
               that
               passes
               
               through
               it
               ,
               in
               the
               most
               advantageous
               way
               .
               And
               that
               the
               Disposition
               of
               the
               Heart
               ,
               even
               when
               men
               have
               no
               sense
               of
               it
               in
               the
               Part
               it self
               ,
               may
               be
               of
               moment
               as
               to
               health
               and
               sickness
               ,
               will
               appear
               credible
               ,
               if
               we
               reflect
               on
               two
               thing
               .
               One
               ,
               that
               a
               living
               Human
               Body
               is
               not
               a
               meer
               Aggregate
               of
               Flesh
               ,
               Bones
               ,
               &c.
               
               But
               an
               exquisitely
               contriv'd
               ,
               and
               very
               sensible
               Engine
               ;
               Whose
               Parts
               are
               easily
               set
               a
               work
               by
               proper
               ,
               though
               very
               Minute
               ,
               Agents
               ;
               And
               may
               ,
               by
               their
               Action
               upon
               one
               another
               ,
               perform
               far
               greater
               things
               ,
               than
               could
               be
               expected
               from
               the
               bare
               Energy
               of
               the
               Agents
               ,
               that
               first
               put
               them
               into
               Motion
               .
               The
               Second
               ,
               (
               which
               supposes
               the
               first
               ,
               )
               that
               the
               Disposition
               of
               the
               Heart
               ,
               being
               ,
               though
               perhaps
               insensibly
               ,
               chang'd
               ,
               it
               may
               produce
               a
               notable
               Alteration
               in
               the
               Motions
               of
               the
               Blood
               ,
               and
               its
               passage
               through
               the
               Heart
               ,
               in
               point
               of
               quantity
               ,
               celerity
               ,
               or
               both
               .
            
             
               How
               much
               this
               change
               in
               the
               Circulation
               may
               in
               many
               Cases
               conduce
               
               to
               sickness
               or
               recovery
               may
               partly
               appear
               by
               the
               Effects
               of
               vehement
               or
               durable
               passions
               of
               the
               mind
               .
               As
               't
               is
               observ'd
               ,
               that
               in
               a
               deep
               sorrow
               ,
               which
               does
               in
               a
               manner
               straiten
               the
               Passages
               of
               the
               Heart
               ,
               the
               Blood
               being
               too
               sparingly
               dispens'd
               ,
               the
               enlivening
               Spirits
               are
               not
               generated
               plentifully
               enough
               ;
               And
               (
               besides
               other
               bad
               Effects
               of
               this
               State
               of
               the
               Heart
               )
               the
               Blood
               is
               so
               dispirited
               ,
               as
               (
               in
               these
               Parts
               of
               Europe
               )
               to
               dispose
               the
               Body
               to
               the
               Scurvy
               ,
               which
               does
               either
               produce
               or
               irritate
               divers
               other
               Maladies
               .
               We
               see
               also
               ,
               that
               the
               Passion
               of
               shame
               does
               oftentimes
               suddenly
               alter
               the
               Motion
               of
               the
               Blood
               ,
               and
               make
               it
               swell
               the
               little
               Vessels
               that
               lye
               under
               the
               Cuticula
               of
               the
               Face
               ,
               and
               sometimes
               other
               Parts
               ;
               as
               is
               very
               manifest
               in
               young
               Maids
               ,
               and
               other
               Persons
               of
               a
               Delicate
               Complexion
               ,
               the
               white
               Part
               of
               whose
               Faces
               in
               blushing
               turns
               Red.
               The
               like
               Effect
               I
               have
               seen
               produc'd
               by
               a
               great
               and
               sudden
               Joy.
               And
               though
               Grief
               ,
               which
               is
               the
               opposite
               Passion
               
               to
               it
               ,
               has
               been
               usually
               taken
               notice
               of
               ,
               as
               a
               thing
               that
               deads
               the
               Appetite
               to
               meat
               ;
               Yet
               so
               much
               does
               depend
               upon
               a
               well
               moderated
               Transmission
               of
               the
               Blood
               ,
               that
               it
               has
               been
               observ'd
               in
               divers
               Persons
               ,
               and
               I
               have
               known
               an
               eminent
               Instance
               of
               it
               ,
               that
               great
               Joy
               has
               very
               much
               lessen'd
               Hunger
               :
               Of
               which
               Effect
               
                 Mr.
                 Des
                 Cartes
              
               ingeniously
               attempts
               to
               derive
               the
               cause
               ,
               from
               the
               vary'd
               Dilatation
               and
               Motions
               of
               the
               Heart
               .
               And
               it
               seems
               not
               absur'd
               to
               conceive
               ,
               that
               such
               like
               Motions
               may
               be
               caus'd
               by
               the
               Corpuscles
               of
               a
               Specifick
               Medicine
               ;
               Which
               by
               affecting
               the
               Fibres
               of
               the
               Heart
               ,
               after
               the
               like
               manner
               that
               Joy
               is
               wont
               to
               do
               ,
               may
               produce
               in
               it
               such
               friendly
               Dilatations
               and
               Contractions
               ,
               as
               are
               wont
               to
               flow
               from
               the
               agreeable
               Passions
               .
               In
               favour
               of
               which
               conjecture
               ,
               I
               shall
               take
               notice
               that
               a
               Lady
               of
               my
               acquaintance
               has
               complain'd
               to
               me
               ,
               that
               the
               smell
               of
               perfum'd
               Gloves
               is
               wont
               to
               make
               the
               Blood
               fly
               to
               her
               Face
               ,
               and
               continue
               there
               for
               a
               great
               
               while
               ,
               giving
               it
               such
               a
               colour
               as
               if
               shame
               ,
               or
               joy
               had
               cover'd
               it
               with
               blushes
               .
               And
               the
               like
               she
               says
               she
               has
               observ'd
               in
               others
               of
               her
               Sex.
               But
               having
               in
               another
               Tract
               spoken
               of
               the
               power
               of
               the
               Passions
               of
               the
               mind
               ,
               to
               alter
               the
               state
               of
               the
               Body
               ,
               by
               producing
               changes
               in
               the
               Blood
               ,
               that
               is
               transmitted
               through
               the
               Heart
               ;
               what
               has
               been
               said
               may
               now
               suffice
               to
               make
               it
               credible
               ,
               that
               a
               Specifick
               Remedy
               ,
               by
               peculiarly
               befriending
               the
               Heart
               ,
               may
               contribute
               much
               to
               introduce
               ,
               or
               re-establish
               a
               healthy
               Crasis
               in
               the
               Blood.
               And
               this
               being
               thus
               rectified
               ,
               and
               invigorated
               it self
               ,
               may
               both
               befriend
               the
               Body
               in
               general
               ,
               and
               conduce
               to
               the
               removal
               of
               some
               particular
               Diseases
               ,
               by
               strengthening
               ,
               and
               perhaps
               too
               exciting
               ,
               the
               particular
               part
               ,
               in
               which
               the
               peccant
               matter
               resides
               ,
               to
               subdue
               or
               expel
               that
               which
               it
               already
               harbours
               ,
               and
               resist
               any
               accession
               of
               more
               .
               And
               the
               Blood
               ,
               being
               it self
               well
               constituted
               ,
               as
               well
               as
               the
               stable
               Parts
               corroborated
               ,
               the
               
               Specifick
               Medicine
               that
               produces
               these
               good
               effects
               ,
               may
               be
               said
               to
               cure
               ,
               tho'
               perhaps
               but
               slowly
               ,
               divers
               particular
               Diseases
               ;
               such
               as
               those
               elsewhere
               mention'd
               in
               this
               Paper
               ,
               which
               to
               continue
               ,
               must
               be
               frequently
               supplyed
               with
               vitious
               matter
               by
               the
               Circulating
               Blood.
               
            
          
           
             
               EXPERIMENT
               VI.
               
            
             
               Sometimes
               a
               Specifick
               Remedy
               may
               unite
               its
               Particles
               with
               those
               of
               the
               Peccant
               matter
               ,
               and
               with
               them
               constitute
               a
               
                 Neutrum
                 quid
              
               ,
               that
               may
               be
               easily
               proscrib'd
               ,
               or
               not
               necessary
               to
               be
               expell'd
               .
            
             
               This
               I
               take
               to
               be
               one
               of
               the
               most
               proper
               and
               genuine
               ways
               of
               doing
               good
               ,
               that
               belongs
               to
               a
               Specifick
               Medicine
               ,
               as
               such
               ,
               because
               in
               this
               operation
               an
               effect
               is
               produc'd
               ,
               either
               without
               the
               assistance
               ,
               or
               beyond
               the
               meer
               power
               ,
               of
               the
               manifest
               qualities
               (
               as
               Physicians
               call
               them
               )
               of
               the
               remedy
               ;
               
               and
               the
               cure
               or
               relief
               the
               Patient
               finds
               ,
               is
               usually
               attain'd
               without
               violence
               ,
               and
               without
               tormenting
               or
               much
               disordering
               him
               .
            
             
               This
               way
               of
               working
               of
               a
               Specifick
               Medicine
               is
               of
               near
               affinity
               with
               one
               or
               two
               of
               those
               formerly
               discours'd
               of
               ;
               but
               yet
               these
               ways
               differ
               in
               some
               things
               ,
               as
               may
               be
               gather'd
               by
               the
               sequel
               of
               §
               this
               discourse
               §
               sometimes
               when
               a
               certain
               kind
               of
               Acid
               has
               impregnated
               the
               Blood
               ,
               or
               lodg'd
               it self
               in
               some
               stable
               part
               ,
               as
               the
               Liver
               ,
               Spleen
               ,
               Kidneys
               ,
               &c.
               
               The
               Corpuscles
               of
               a
               Specifick
               may
               ,
               without
               any
               sensible
               luctation
               or
               conflict
               ,
               which
               usually
               happens
               when
               Acids
               are
               mortify'd
               by
               Sapid
               Alkalies
               ,
               be
               so
               qualifi'd
               ,
               as
               both
               to
               make
               Coalitions
               with
               the
               small
               Parts
               of
               the
               Peccant
               Acid
               ,
               and
               with
               them
               to
               constitute
               little
               Concretions
               ,
               which
               differing
               from
               the
               minute
               Parts
               of
               the
               Acid
               ,
               either
               in
               Bulk
               ,
               Figure
               ,
               Solidity
               ,
               Stifness
               ,
               Motion
               ,
               or
               in
               two
               or
               more
               of
               these
               ;
               may
               be
               quite
               of
               another
               nature
               ,
               and
               of
               a
               much
               innocenter
               ,
               
               than
               the
               Acid
               was
               before
               't
               was
               so
               corrected
               .
               Of
               this
               we
               may
               be
               furnished
               with
               a
               notable
               Illustration
               ,
               by
               what
               I
               have
               elsewhere
               taken
               notice
               of
               about
               
                 Aqua
                 Fortis
              
               it self
               ;
               for
               as
               corrosive
               a
               Menstruum
               as
               that
               is
               ,
               yet
               by
               digesting
               it
               ,
               and
               perhaps
               ,
               distilling
               it
               too
               ,
               with
               an
               equal
               ,
               or
               rather
               double
               weight
               of
               Ardent
               Spirit
               ,
               I
               found
               the
               highly
               Acid
               Liquor
               would
               be
               so
               chang'd
               ,
               as
               not
               to
               retain
               any
               sensible
               corrosiveness
               ;
               and
               exchange
               its
               piercing
               Stink
               and
               great
               Acidity
               ,
               for
               a
               not
               only
               inoffensive
               ,
               but
               pleasant
               Scent
               ,
               and
               a
               grateful
               and
               possitively
               sweetish
               Tast
               .
               Which
               brings
               into
               my
               mind
               the
               practice
               of
               a
               President
               of
               the
               Famous
               London
               Colledge
               ,
               who
               (
               as
               himself
               told
               me
               )
               was
               wont
               to
               relieve
               a
               Patient
               of
               very
               great
               Quality
               in
               Nephritick
               Torments
               ,
               by
               giving
               her
               a
               good
               Dose
               of
               an
               inflammable
               Spirit
               .
               (
               But
               this
               upon
               the
               by
               .
               )
               I
               have
               elsewhere
               given
               an
               account
               of
               the
               effects
               of
               Spirit
               of
               Wine
               ,
               upon
               several
               other
               Acid
               Menstruums
               ,
               wherewith
               I
               mingl'd
               and
               digested
               it
               ;
               by
               
               which
               it
               may
               appear
               ,
               that
               it
               does
               not
               work
               upon
               them
               uniformly
               ,
               as
               they
               are
               all
               of
               them
               Acids
               ;
               but
               differingly
               enough
               ,
               according
               to
               the
               Nature
               and
               Proportion
               of
               the
               Acid
               Corpuscles
               ,
               with
               which
               the
               vinous
               Spirits
               are
               brought
               to
               be
               associated
               .
            
             
               And
               ,
               to
               shew
               that
               this
               change
               and
               contemperation
               of
               the
               Menstruum
               by
               the
               Spirit
               of
               Wine
               ,
               is
               produc'd
               rather
               by
               a
               peculiar
               fitness
               of
               the
               convening
               Corpuscles
               of
               both
               ,
               than
               by
               the
               contrariety
               or
               hostility
               ,
               that
               the
               vinous
               Spirit
               ,
               which
               some
               Moderns
               will
               have
               to
               be
               an
               Alcaly
               ,
               has
               to
               the
               
                 Aqua
                 Fortis
              
               as
               an
               Acid
               ;
               I
               shall
               add
               ,
               that
               pure
               Spirit
               of
               Wine
               being
               mixt
               in
               a
               due
               proportion
               with
               
                 Highly
                 rectifi'd
              
               Spirit
               of
               Urine
               ;
               which
               is
               reckon'd
               by
               Chymists
               among
               volatile
               Alcalies
               ,
               and
               of
               which
               a
               drop
               or
               two
               is
               so
               fiery
               upon
               the
               tongue
               ;
               as
               to
               be
               ready
               to
               burn
               it
               ,
               or
               to
               blister
               it
               ;
               this
               Vinous
               Spirit
               I
               say
               ,
               will
               very
               much
               take
               off
               the
               caustick
               penetrancy
               of
               the
               urinous
               one
               ,
               and
               compose
               with
               it
               a
               Salt
               much
               
               more
               moderate
               than
               the
               Spirit
               was
               ,
               and
               which
               being
               sublim'd
               ,
               or
               (
               which
               is
               better
               but
               harder
               to
               be
               done
               ,
               
               )
               reduc'd
               into
               a
               Liquor
               ,
               affords
               a
               mixture
               of
               no
               little
               use
               in
               fome
               Fevers
               and
               other
               Diseases
               as
               a
               Medicine
               ;
               and
               with
               a
               small
               ,
               if
               skilful
               alteration
               ,
               is
               of
               great
               use
               in
               divers
               Chymical
               Experiments
               as
               a
               Menstruum
               .
            
             
               A
               few
               grains
               of
               Glass
               of
               Antimony
               made
               without
               addition
               ,
               being
               taken
               inwardly
               ,
               will
               vehemently
               both
               vomit
               and
               purge
               .
               But
               tho'
               Wine
               ,
               notwithstanding
               its
               copious
               Spirits
               ,
               will
               ,
               if
               it
               be
               well
               impregnated
               with
               the
               Corpuscles
               of
               this
               Glass
               ,
               work
               upwards
               and
               downwards
               violently
               enough
               ;
               yet
               of
               Spirit
               of
               Vinegar
               ,
               that
               is
               ,
               of
               degenerated
               Wine
               ,
               be
               for
               a
               competent
               time
               digested
               upon
               this
               Glass
               finely
               powder'd
               ,
               and
               ,
               when
               the
               Liquor
               is
               sufficiently
               impregnated
               with
               the
               Particles
               of
               the
               Glass
               ,
               be
               abstracted
               from
               it
               ,
               there
               will
               emerge
               from
               the
               Antimonial
               and
               Acetous
               Corpuscles
               ,
               a
               multitude
               of
               minute
               Concretions
               ,
               of
               which
               many
               grains
               may
               
               be
               given
               without
               ordinarily
               provoking
               either
               Vomits
               or
               Stools
               :
               Which
               correction
               may
               hint
               ,
               that
               't
               is
               not
               necessary
               that
               all
               Mortifications
               usefully
               made
               by
               Medicines
               ,
               should
               be
               of
               Acids
               ,
               since
               here
               we
               see
               ,
               that
               Acids
               themselves
               prove
               Correctors
               .
               And
               perhaps
               it
               may
               be
               by
               some
               such
               kind
               of
               Combinations
               ,
               that
               some
               Poisons
               (
               for
               I
               do
               not
               think
               they
               all
               work
               one
               way
               ,
               or
               peculiarly
               assault
               the
               heart
               )
               may
               be
               subdued
               .
               And
               I
               have
               sometimes
               suspected
               ,
               that
               it
               may
               as
               probably
               be
               upon
               this
               account
               ,
               as
               upon
               any
               that
               has
               been
               offer'd
               ,
               that
               a
               man
               stung
               with
               a
               Scorpion
               may
               be
               cur'd
               ,
               by
               crushing
               the
               Animal
               that
               stung
               him
               upon
               the
               hurt
               ,
               as
               is
               prescrib'd
               by
               many
               Physicians
               ,
               and
               as
               an
               acquaintance
               of
               mine
               told
               me
               ,
               he
               try'd
               upon
               himself
               (
               as
               another
               Virtuoso
               did
               on
               a
               Souldier
               )
               with
               good
               success
               :
               And
               when
               I
               consider
               what
               a
               multitude
               and
               variety
               of
               figures
               may
               fit
               the
               Corpuscles
               that
               are
               endowed
               with
               them
               ,
               to
               make
               Coalitions
               very
               different
               from
               both
               
               the
               component
               parts
               ;
               I
               can
               scarce
               think
               it
               very
               improbable
               ,
               that
               in
               a
               Patients
               Body
               there
               may
               be
               made
               ,
               between
               the
               Corpuscles
               of
               the
               Peccant
               matter
               ,
               and
               those
               of
               a
               Medicine
               ,
               such
               useful
               combinations
               as
               may
               produce
               resulting
               Concretions
               ,
               innocent
               ,
               if
               not
               also
               beneficial
               .
            
             
               If
               I
               had
               leizure
               ,
               and
               thought
               it
               fit
               ,
               I
               could
               easily
               add
               a
               great
               number
               of
               instances
               ,
               about
               such
               changes
               of
               Colours
               ,
               Odours
               ,
               Tasts
               ,
               and
               other
               qualities
               ,
               as
               are
               produc'd
               by
               the
               coallescence
               of
               the
               small
               parts
               of
               differing
               Bodies
               ,
               and
               discourse
               of
               the
               natural
               consequent
               of
               such
               Coalitions
               :
               but
               having
               done
               that
               sufficiently
               in
               other
               Papers
               ,
               it
               will
               be
               here
               more
               proper
               to
               intimate
               to
               you
               ,
               that
               when
               a
               particle
               of
               peccant
               matter
               comes
               to
               be
               associated
               with
               one
               of
               a
               Specifick
               Medicine
               ,
               that
               combination
               may
               alter
               it
               for
               the
               better
               ,
               not
               only
               by
               changing
               its
               bigness
               and
               figure
               ,
               but
               also
               by
               encreasing
               ,
               or
               lessening
               its
               stifness
               ,
               and
               its
               solidity
               ,
               and
               giving
               a
               new
               modification
               to
               its
               motion
               ;
               as
               
               a
               little
               attention
               to
               the
               natural
               consequences
               of
               the
               Coalitions
               of
               Bodies
               ,
               may
               easily
               induce
               you
               to
               grant
               .
            
             
               And
               I
               shall
               add
               (
               as
               it
               were
               
                 ex
                 abundanti
              
               )
               that
               the
               small
               Concretions
               ,
               made
               by
               the
               union
               of
               some
               Morbifick
               with
               some
               Medicinal
               Corpuscles
               ,
               may
               not
               only
               become
               innocent
               ,
               but
               sometimes
               also
               beneficial
               ,
               which
               may
               be
               illustrated
               by
               what
               happens
               by
               a
               further
               preparation
               ,
               to
               common
               sublimate
               ;
               for
               though
               this
               be
               a
               substance
               so
               highly
               corrosive
               and
               mischievous
               ,
               that
               a
               few
               grains
               of
               it
               may
               suffice
               to
               kill
               a
               man
               ;
               yet
               by
               making
               a
               Coalescence
               of
               it
               with
               less
               than
               its
               weight
               of
               Quicksilver
               ,
               which
               is
               a
               Body
               insipid
               as
               well
               as
               modorous
               ,
               the
               Corrosive
               sublimate
               will
               be
               so
               alter'd
               and
               tam'd
               ,
               as
               to
               be
               turn'd
               into
               what
               Chymists
               call
               ,
               because
               't
               is
               freed
               from
               sharpness
               ,
               
                 Mercurius
                 Dulcis
              
               ;
               which
               if
               it
               be
               skilfully
               prepar'd
               and
               given
               ,
               though
               in
               the
               quantity
               of
               many
               grains
               ,
               is
               not
               only
               for
               the
               most
               part
               an
               innocent
               thing
               ,
               but
               a
               very
               good
               Medicine
               ,
               and
               that
               perhaps
               in
               more
               
               cases
               than
               Physicians
               generally
               know
               it
               to
               be
               good
               in
               .
            
             
               The
               newly
               mention'd
               account
               may
               hint
               to
               us
               a
               probable
               Argument
               ,
               to
               show
               ,
               that
               ,
               notwithstanding
               all
               the
               digestions
               and
               changes
               that
               a
               Specifick
               Medicine
               may
               receive
               in
               its
               way
               ,
               it
               may
               prove
               a
               salutary
               one
               ,
               when
               it
               arrives
               at
               the
               Part
               it
               should
               relieve
               .
               For
               ,
               tho'
               the
               Corpuscles
               of
               the
               Medicine
               should
               in
               their
               way
               to
               the
               Part
               affected
               be
               considerably
               chang'd
               ,
               yet
               't
               is
               possible
               that
               these
               alter'd
               Corpuscles
               may
               ,
               by
               that
               very
               alteration
               ,
               be
               made
               Medicinal
               ;
               since
               they
               may
               be
               qualifi'd
               ,
               (
               even
               by
               those
               changes
               )
               when
               they
               arrive
               at
               the
               Part
               affected
               ,
               to
               combine
               themselves
               strictly
               with
               some
               Corpuscles
               ,
               whether
               Morbifick
               or
               others
               ,
               that
               they
               find
               already
               there
               ;
               and
               may
               with
               them
               compose
               new
               Concretions
               that
               may
               acquire
               a
               new
               Nature
               very
               friendly
               to
               the
               Patient
               .
               Something
               Analogical
               to
               this
               we
               may
               observe
               in
               Asparagus
               ,
               which
               being
               eaten
               ,
               afford
               store
               of
               Particles
               ,
               that
               mixing
               with
               
               those
               they
               meet
               with
               in
               the
               Kidneys
               or
               the
               Bladder
               ,
               produce
               a
               new
               Odour
               ,
               very
               differing
               ,
               both
               from
               that
               of
               meer
               Urine
               ,
               and
               from
               that
               of
               the
               Plant
               it self
               .
               And
               so
               if
               good
               Turpentine
               be
               taken
               at
               the
               Mouth
               ,
               't
               is
               known
               that
               arriving
               at
               the
               Kidneys
               and
               Bladder
               ,
               it
               will
               mingle
               its
               minute
               Parts
               with
               those
               it
               meets
               with
               there
               ;
               whence
               will
               emerge
               Corpuscles
               ,
               that
               will
               impregnate
               the
               Urine
               with
               a
               very
               differing
               Odour
               ,
               from
               that
               which
               belongs
               to
               either
               of
               the
               Liquors
               ,
               since
               it
               oftentimes
               has
               a
               fragrancy
               somewhat
               like
               the
               smell
               of
               Violets
               .
            
             
               Before
               I
               conclude
               this
               Paper
               ,
               't
               is
               like
               it
               will
               be
               thought
               fit
               that
               I
               should
               take
               notice
               of
               a
               difficulty
               ,
               that
               I
               know
               maybe
               objected
               ,
               if
               not
               against
               the
               past
               discourse
               ,
               yet
               against
               the
               sufficiency
               of
               it
               to
               answer
               the
               design
               I
               propose
               to
               my self
               in
               writing
               it
               .
               For
               it
               may
               be
               said
               ,
               that
               ,
               whereas
               my
               Arguments
               and
               Explications
               suppose
               all
               along
               ,
               that
               the
               
                 Specifick
                 Remedies
              
               are
               taken
               in
               at
               the
               Mouth
               ;
               't
               is
               known
               
               that
               divers
               of
               the
               Asserters
               of
               Specificks
               reckon
               among
               them
               ,
               some
               that
               are
               not
               by
               swallowing
               taken
               into
               the
               Body
               ,
               but
               only
               outwardly
               apply'd
               ,
               or
               perhaps
               do
               but
               barely
               touch
               it
               ;
               as
               may
               be
               observ'd
               in
               Amulets
               ,
               Rings
               ,
               &c.
               
               On
               occasion
               of
               this
               considerable
               difficulty
               ,
               I
               have
               ,
               if
               I
               misremember
               not
               ,
               represented
               divers
               things
               in
               another
               Tract
               .
               But
               however
               it
               may
               be
               fit
               in
               this
               place
               ,
               briefly
               to
               say
               somewhat
               ,
               by
               way
               of
               Answerto
               it
               .
               We
               may
               then
               take
               notice
               ,
               that
               the
               confidence
               with
               which
               many
               Physicians
               reject
               ,
               and
               some
               of
               them
               deride
               ,
               
                 External
                 Specificks
              
               ,
               if
               I
               may
               so
               call
               them
               ,
               seems
               to
               be
               built
               upon
               these
               two
               things
               :
               The
               One
               ,
               that
               the
               Medicine
               cannot
               in
               part
               ,
               as
               't
               is
               certain
               it
               do's
               not
               in
               the
               Mass
               ,
               get
               into
               the
               Body
               ;
               and
               the
               other
               ,
               that
               ,
               in
               case
               a
               Specifick
               should
               have
               some
               part
               of
               it
               subtil
               enough
               to
               gain
               admittance
               ,
               that
               Part
               must
               be
               too
               small
               and
               inconsiderable
               ,
               to
               be
               able
               to
               produce
               in
               the
               Body
               any
               such
               notable
               change
               ,
               as
               is
               necessary
               to
               the
               expulsion
               of
               Peccant
               Humours
               ,
               
               and
               the
               conquering
               of
               a
               Disease
               .
            
             
               As
               to
               the
               former
               of
               these
               Grounds
               ,
               I
               largely
               enough
               show
               in
               another
               Paper
               ,
               *
               that
               a
               Mans
               Skin
               ,
               tho'
               it
               seems
               an
               entire
               continued
               Body
               ,
               is
               really
               perforated
               with
               a
               great
               multitude
               ,
               and
               perhaps
               a
               not
               inconsiderable
               variety
               ,
               of
               little
               Cutlets
               and
               Inlets
               ,
               which
               we
               call
               Pores
               ;
               many
               of
               which
               are
               visible
               ,
               even
               in
               the
               Skins
               of
               dead
               Animals
               ,
               by
               good
               Microscopes
               ;
               and
               others
               are
               manifestly
               inferr'd
               ,
               from
               the
               numerous
               little
               drops
               that
               cover
               all
               the
               Skin
               ,
               at
               the
               first
               Eruption
               of
               Sweat.
               And
               that
               these
               little
               Perforations
               may
               be
               Inlets
               to
               the
               finer
               Particles
               of
               Externally
               apply'd
               Medicines
               ,
               may
               appear
               probable
               by
               several
               Phaenomena
               ,
               such
               as
               these
               .
               That
               Water
               will
               soak
               through
               the
               Pores
               of
               a
               fine
               Bladder
               ,
               and
               dissolve
               Salt
               of
               Tartar
               ,
               or
               even
               white
               Sugar
               ,
               contain'd
               in
               it
               :
               That
               I
               have
               prepar'd
               a
               certain
               Liquor
               ,
               whose
               Fumes
               ,
               tho'
               not
               agitated
               by
               Heat
               ,
               would
               quickly
               penetrate
               
               divers
               Membrans
               of
               dead
               Animals
               ,
               and
               manifestly
               work
               on
               Metalline
               Bodies
               wrapt
               up
               in
               them
               :
               That
               't
               is
               a
               known
               thing
               ,
               that
               Quicksilver
               outwardly
               apply'd
               in
               Ointments
               ,
               Girdles
               ,
               &c.
               will
               get
               in
               at
               the
               Pores
               of
               the
               Skin
               ,
               and
               invade
               the
               Internal
               Parts
               of
               the
               Body
               ,
               and
               stay
               there
               longer
               ,
               and
               perhaps
               too
               operate
               more
               ,
               than
               the
               Physician
               desired
               .
               And
               when
               once
               the
               Effluvia
               of
               these
               Externally
               apply'd
               Remedies
               have
               gain'd
               admittance
               at
               the
               Pores
               of
               the
               Skin
               ,
               't
               is
               not
               very
               difficult
               to
               conceive
               ,
               how
               they
               may
               proceed
               further
               .
               For
               underneath
               the
               Cuticula
               or
               Scarf
               Skin
               ,
               and
               close
               to
               it
               ,
               there
               are
               so
               great
               a
               multitude
               of
               Capillary
               Vessels
               ,
               that
               you
               can
               scarce
               thrust
               a
               small
               Pin
               into
               any
               Part
               ,
               but
               that
               the
               point
               of
               it
               will
               meet
               and
               tear
               some
               of
               these
               little
               Vessels
               ;
               as
               will
               appear
               by
               a
               small
               drop
               of
               Blood
               ,
               that
               will
               be
               made
               to
               issue
               out
               at
               the
               new
               made
               hole
               ,
               as
               small
               as
               it
               is
               .
               To
               which
               instance
               ,
               if
               it
               were
               necessary
               ,
               I
               could
               add
               divers
               others
               of
               the
               multitude
               and
               
               spreading
               of
               the
               Capillary
               Vessels
               ,
               that
               lie
               close
               beneath
               the
               Skin
               ,
               and
               for
               the
               most
               part
               carry
               Blood
               ,
               tho'
               some
               of
               them
               may
               contain
               other
               Juices
               ,
               and
               discharge
               their
               recrements
               by
               Sweat
               ,
               or
               insensible
               Transpiration
               ,
               at
               the
               Cutaneous
               Outlets
               .
               Now
               these
               Capillary
               Vessels
               ,
               as
               small
               as
               they
               are
               ,
               having
               their
               Cavities
               immediately
               continu'd
               with
               those
               of
               less
               slender
               ones
               ,
               and
               by
               their
               intervention
               with
               those
               of
               the
               greater
               ,
               which
               are
               branches
               of
               the
               greatest
               of
               all
               ;
               the
               Corpuscles
               of
               the
               Medicine
               ,
               once
               got
               into
               the
               Capillary
               Vessels
               ,
               may
               have
               an
               easy
               passage
               ,
               by
               means
               of
               the
               Liquors
               they
               contain
               ,
               into
               these
               greater
               branches
               of
               the
               principal
               Veins
               ,
               and
               so
               ,
               by
               vertue
               of
               the
               Circulation
               ,
               come
               to
               be
               quickly
               mingled
               with
               the
               Mass
               of
               Blood
               ,
               and
               by
               it
               may
               be
               easily
               convey'd
               to
               all
               the
               Parts
               of
               the
               Body
               :
               As
               it
               has
               been
               divers
               times
               observ'd
               ,
               *
               that
               Arsenical
               Amulets
               worn
               upon
               the
               Breast
               ,
               did
               ,
               
               tho'
               they
               scarce
               touch'd
               the
               Skin
               ,
               produce
               threatning
               Distempers
               in
               the
               Heart
               ,
               and
               several
               mischievous
               Symptoms
               in
               other
               Parts
               of
               the
               Body
               .
               And
               I
               find
               it
               recorded
               in
               good
               Authors
               ,
               that
               Cantharides
               ,
               even
               when
               but
               held
               in
               the
               Hand
               ,
               nay
               sometimes
               ,
               tho'
               but
               carried
               in
               ones
               Pocket
               ,
               transmitted
               their
               hurtful
               Effluvia
               as
               far
               as
               the
               Bladder
               ,
               and
               excited
               great
               Pain
               and
               other
               bad
               Symptoms
               there
               .
            
             
               As
               for
               the
               second
               Ground
               on
               which
               Specifick
               Remedies
               are
               rejected
               ,
               that
               ,
               tho'
               they
               could
               get
               entrance
               into
               the
               Body
               ,
               yet
               it
               would
               be
               but
               by
               their
               Effluvia
               ;
               and
               these
               are
               no
               way
               likely
               to
               prove
               efficacious
               enough
               ,
               to
               have
               any
               considerable
               effect
               upon
               an
               Internal
               Disease
               :
               To
               remove
               this
               difficulty
               ,
               I
               shall
               briefly
               observe
               ;
            
             
               1.
               
               That
               the
               number
               of
               the
               Corpuscles
               ,
               that
               may
               pass
               from
               the
               outward
               Medicine
               into
               the
               Body
               ,
               may
               be
               far
               greater
               ,
               and
               therefore
               make
               them
               more
               considerable
               ,
               than
               most
               men
               are
               apt
               to
               think
               .
               This
               may
               be
               
               rendred
               probable
               ,
               by
               the
               great
               multitudes
               of
               Odorous
               ,
               and
               consequently
               Sensible
               ,
               Expirations
               ,
               that
               are
               continually
               emitted
               for
               a
               very
               long
               time
               together
               ,
               by
               Ambergreece
               ,
               Musk
               ,
               Civet
               ,
               and
               much
               more
               by
               skilfully
               made
               Compositions
               of
               them
               .
               And
               that
               also
               subtil
               Effluvia
               ,
               even
               without
               the
               assistance
               of
               Heat
               ,
               may
               quickly
               penetrate
               Membrans
               so
               plentifully
               ,
               as
               to
               act
               on
               stable
               Bodies
               contain'd
               in
               them
               ,
               I
               have
               intimated
               a
               little
               above
               ,
               and
               have
               experimentally
               made
               appear
               to
               divers
               curious
               men
               .
            
             
               2.
               
               That
               the
               Corpuscles
               of
               a
               Medicine
               may
               retain
               their
               Nature
               ,
               and
               not
               loose
               their
               power
               of
               operating
               ,
               notwithstanding
               their
               being
               ,
               as
               it
               were
               ,
               strain'd
               through
               the
               Skin
               ;
               as
               may
               be
               argued
               from
               the
               Mercury
               ,
               that
               we
               not
               long
               since
               mention'd
               to
               have
               been
               found
               in
               the
               form
               of
               Quick-silver
               ,
               in
               the
               Bodies
               of
               some
               men
               ,
               that
               had
               been
               too
               frequently
               anonited
               with
               Mercury
               ,
               mix'd
               up
               with
               unctuous
               things
               into
               an
               Ointment
               :
               By
               which
               
               the
               Patient
               may
               be
               as
               long
               and
               violently
               Salivated
               ,
               as
               if
               he
               had
               swallow'd
               a
               Bolus
               or
               Pills
               with
               Mercury
               .
            
             
               And
               so
               I
               have
               divers
               times
               observ'd
               ,
               as
               I
               doubt
               not
               but
               others
               have
               oftner
               done
               ,
               that
               a
               little
               Opium
               ,
               mix'd
               up
               with
               other
               Ingredients
               for
               Plaisters
               ,
               did
               by
               outward
               application
               take
               off
               the
               Acute
               Pains
               of
               inward
               Parts
               ,
               tho'
               moderately
               remote
               from
               the
               Plaister
               .
            
             
               3.
               
               And
               that
               the
               Corpuscles
               of
               a
               Specifick
               may
               on
               divers
               occasions
               act
               more
               powerfully
               ,
               by
               getting
               in
               at
               the
               Pores
               of
               the
               Skin
               ,
               than
               if
               the
               Remedy
               that
               afforded
               them
               had
               been
               taken
               in
               at
               the
               Mouth
               :
               Because
               if
               it
               had
               ,
               the
               Particles
               might
               be
               divided
               ,
               or
               perhaps
               on
               other
               accounts
               ,
               (
               as
               by
               dilution
               ,
               composition
               with
               those
               of
               the
               Chyle
               ,
               &c.
               )
               much
               alter'd
               ,
               by
               the
               Ferment
               or
               the
               Menstruum
               of
               the
               Stomach
               ,
               by
               their
               Filtration
               through
               the
               Guts
               ,
               and
               their
               long
               and
               winding
               passage
               through
               them
               and
               the
               Lymphiducts
               ,
               before
               they
               arrive
               at
               the
               Heart
               ,
               to
               be
               mingled
               with
               the
               Blood
               ;
               
               whereas
               the
               Corpuscles
               of
               the
               External
               Specifick
               ,
               presently
               after
               they
               are
               past
               the
               Skin
               ,
               get
               into
               the
               Capillary
               Vessels
               of
               the
               Blood
               that
               lie
               under
               it
               ,
               and
               by
               their
               means
               are
               speedily
               mix'd
               with
               the
               Circulating
               Mass
               of
               that
               Liquor
               ,
               and
               so
               escape
               the
               formerly
               mention'd
               alterations
               ,
               that
               other
               Medicines
               are
               subject
               to
               before
               they
               are
               admitted
               into
               the
               Mass
               of
               Blood.
               By
               which
               it
               may
               appear
               ,
               that
               those
               Physicians
               are
               much
               mistaken
               ,
               that
               think
               a
               Topical
               Medicine
               can
               at
               best
               relieve
               but
               the
               Part
               't
               is
               apply'd
               to
               ,
               because
               its
               Corpuscles
               cannot
               be
               suppos'd
               to
               reach
               beyond
               that
               Part
               of
               the
               Body
               ,
               that
               lies
               very
               near
               the
               Medicine
               they
               issue
               from
               .
               But
               ,
               tho'
               this
               reasoning
               might
               be
               excusable
               enough
               ,
               if
               not
               allowable
               ,
               before
               the
               Circulation
               of
               the
               Blood
               was
               discover'd
               ,
               yet
               ,
               now
               't
               is
               known
               how
               great
               an
               intercourse
               that
               Liquor
               maintains
               between
               distant
               Parts
               of
               the
               Body
               ,
               the
               Argument
               is
               not
               seasonable
               .
            
             
               And
               on
               this
               occasion
               ,
               I
               shall
               add
               an
               advertisement
               ,
               that
               I
               remember
               
               not
               I
               have
               met
               with
               in
               Authors
               ;
               which
               is
               ,
               that
               Body
               's
               outwardly
               apply'd
               may
               prove
               Specificks
               for
               some
               Diseases
               or
               Distempers
               ,
               that
               one
               would
               not
               think
               them
               very
               good
               for
               ,
               by
               the
               bare
               knowledge
               of
               their
               effects
               when
               taken
               in
               at
               the
               mouth
               .
               Thus
               Camphire
               swallow'd
               ,
               is
               ,
               in
               the
               dose
               of
               a
               very
               few
               grains
               ,
               a
               great
               heater
               of
               the
               Blood
               ,
               and
               is
               in
               some
               Country's
               ,
               perhaps
               not
               altogether
               without
               reason
               ,
               extoll'd
               by
               Physicians
               in
               some
               kinds
               of
               ill
               condition'd
               Fevers
               :
               but
               outwardly
               it
               is
               apply'd
               to
               take
               off
               those
               Rednesses
               of
               the
               Face
               ,
               that
               are
               thought
               to
               proceed
               from
               Heat
               of
               Blood
               ;
               and
               't
               is
               us'd
               in
               Ointments
               against
               Burns
               .
               So
               Spirit
               of
               Wine
               ,
               that
               is
               so
               hot
               when
               drunk
               ,
               is
               a
               very
               good
               remedy
               to
               take
               out
               the
               fire
               ,
               as
               they
               speak
               ,
               in
               Burns
               ,
               especially
               if
               the
               Part
               be
               early
               moistend
               with
               it
               .
               Bread
               ,
               that
               is
               counted
               so
               moderate
               and
               well
               temper'd
               and
               Aliment
               ,
               when
               eaten
               ,
               if
               it
               be
               chew'd
               and
               outwardly
               apply'd
               ,
               hath
               considerable
               vertues
               in
               several
               external
               affections
               .
               And
               I
               know
               an
               
               ancient
               and
               experienc'd
               Physician
               ,
               that
               uses
               to
               purge
               .
               Children
               ,
               that
               will
               not
               easily
               be
               brought
               to
               swallow
               Medicines
               ,
               by
               applying
               something
               to
               their
               Navels
               ,
               that
               do's
               not
               offend
               them
               by
               Colour
               ,
               Smell
               ,
               or
               Griping
               :
               And
               this
               himself
               more
               than
               once
               confess'd
               to
               me
               ,
               is
               but
               an
               ordinary
               Aliment
               ,
               that
               most
               men
               ,
               and
               I
               among
               others
               ,
               have
               frequently
               taken
               unprepar'd
               ,
               which
               he
               freely
               nam'd
               to
               me
               ,
               but
               which
               I
               have
               not
               yet
               had
               opportunity
               to
               make
               Tryal
               of
               .
            
             
               That
               what
               we
               have
               been
               saying
               about
               the
               possible
               efficacy
               of
               external
               Specificks
               ,
               may
               appear
               the
               less
               improbable
               ,
               't
               will
               be
               fit
               to
               take
               notice
               of
               soms
               observations
               ,
               that
               comport
               very
               well
               with
               our
               Doctrine
               .
               And
               though
               the
               Instances
               to
               be
               brought
               will
               not
               be
               all
               of
               them
               of
               remedies
               that
               deserve
               the
               name
               of
               Specificks
               ;
               yet
               ,
               besides
               that
               some
               of
               them
               may
               perhaps
               have
               a
               Title
               to
               it
               ,
               they
               will
               all
               conduce
               to
               show
               ,
               that
               Simples
               or
               Druggs
               externally
               apply'd
               ,
               may
               have
               considerable
               operations
               against
               Internal
               Distempers
               of
               the
               Body
               .
            
             
             
               'T
               were
               easy
               for
               me
               to
               mention
               a
               great
               many
               external
               Specificks
               out
               of
               Physicians
               Books
               .
               But
               I
               purposely
               forbear
               it
               ,
               because
               to
               speak
               freely
               ,
               I
               suspect
               that
               most
               of
               those
               Remedies
               ,
               though
               greatly
               extoll'd
               ,
               have
               been
               but
               little
               examin'd
               ,
               by
               the
               deliverers
               of
               them
               .
               And
               it
               may
               suffice
               for
               my
               present
               purpose
               to
               alledge
               a
               few
               Instances
               that
               have
               been
               recommended
               to
               me
               ,
               either
               by
               my
               own
               experience
               ,
               or
               that
               of
               some
               Friends
               .
               Only
               there
               is
               one
               observation
               that
               is
               so
               solemnly
               and
               expresly
               deliver'd
               by
               Galen
               ,
               upon
               his
               own
               knowledge
               ,
               &
               so
               well
               back'd
               ,
               by
               other
               eminent
               Physicians
               ,
               that
               I
               shall
               let
               it
               lead
               the
               way
               .
               This
               memorable
               story
               ,
               that
               is
               related
               by
               Galen
               ,
               is
               of
               a
               Piony
               Root
               ,
               which
               having
               been
               worn
               as
               ah
               Apensum
               about
               a
               Boy
               ,
               that
               had
               been
               Epileptick
               for
               divers
               months
               ,
               kept
               him
               from
               his
               Disease
               as
               long
               as
               he
               wore
               it
               about
               him
               ;
               but
               when
               by
               an
               accident
               he
               ceas'd
               to
               do
               so
               ,
               the
               Disease
               invaded
               him
               again
               ,
               and
               yet
               by
               applying
               the
               Remedy
               again
               ,
               he
               was
               the
               second
               
               time
               freed
               from
               it
               ,
               which
               Galen
               observing
               ,
               did
               for
               curiosity
               make
               the
               Root
               be
               laid
               aside
               ,
               but
               finding
               the
               Fits
               to
               return
               ,
               he
               imploy'd
               it
               again
               with
               the
               former
               success
               .
            
             
               I
               liv'd
               in
               the
               same
               house
               with
               a
               learned
               and
               Judicious
               Person
               ,
               that
               was
               subject
               to
               be
               Paralytick
               ,
               who
               being
               frequently
               tortur'd
               by
               violent
               Cramps
               ,
               was
               ordinarily
               and
               speedily
               reliev'd
               by
               wearing
               or
               handling
               the
               Tooth
               of
               a
               true
               Hippopotamus
               or
               River-Horse
               .
               And
               he
               affirm'd
               to
               me
               ,
               that
               upon
               leaving
               off
               ,
               the
               use
               of
               it
               ,
               for
               any
               considerable
               time
               ,
               either
               out
               of
               curiosity
               ,
               or
               to
               accommodate
               some
               Friend
               ,
               the
               Fits
               would
               return
               with
               violence
               upon
               him
               .
               I
               remember
               also
               ,
               that
               having
               my self
               been
               for
               some
               years
               frequently
               subject
               to
               Cramps
               ,
               and
               complaining
               of
               it
               to
               a
               Physician
               that
               had
               been
               a
               Traveller
               into
               cold
               Country's
               ,
               he
               told
               me
               ,
               that
               he
               had
               brought
               home
               with
               him
               some
               Rings
               made
               of
               the
               true
               Elks
               hoof
               ,
               from
               a
               place
               where
               these
               Animals
               are
               usually
               imploy'd
               ,
               and
               that
               with
               these
               he
               had
               
               cur'd
               many
               of
               the
               Cramp
               ,
               and
               therewithal
               presented
               me
               one
               to
               make
               tryal
               of
               ,
               which
               I
               the
               more
               willingly
               accepted
               ,
               because
               he
               confess'd
               to
               me
               ,
               that
               divers
               Rings
               that
               were
               sold
               for
               such
               as
               his
               ,
               and
               look'd
               like
               them
               ,
               were
               either
               counterfeit
               or
               of
               no
               efficacy
               .
               And
               tho'
               I
               did
               not
               find
               that
               if
               the
               Cramp
               seiz'd
               me
               in
               the
               calf
               of
               the
               Leg
               ,
               the
               Ring
               would
               much
               relieve
               me
               ,
               yet
               when
               the
               Fits
               were
               but
               moderate
               ,
               and
               in
               other
               Parts
               ,
               especially
               the
               hands
               ,
               I
               found
               my self
               eas'd
               ,
               so
               often
               ,
               and
               so
               soon
               ,
               that
               I
               was
               at
               first
               surpriz'd
               at
               it
               ,
               and
               us'd
               to
               have
               the
               remedy
               laid
               every
               night
               by
               my
               Bed-side
               ,
               to
               have
               it
               ready
               when
               occasion
               should
               require
               .
               And
               that
               which
               I
               thought
               some
               what
               strange
               ,
               was
               ,
               that
               several
               times
               ,
               when
               the
               Cramp
               seiz'd
               my
               Foot
               or
               my
               Toes
               ,
               the
               Pain
               was
               quickly
               remov'd
               ,
               tho'
               I
               apply'd
               the
               Ring
               but
               to
               my
               Finger
               :
               which
               made
               me
               much
               regret
               the
               loss
               of
               it
               .
            
             
               An
               eminent
               Physician
               speaking
               to
               me
               one
               day
               of
               a
               Patient
               of
               his
               ,
               that
               was
               subject
               to
               a
               nocturnal
               
                 Incontinentia
                 
                 Urinae
              
               ,
               that
               was
               very
               inconvenient
               as
               well
               as
               shameful
               ;
               I
               told
               him
               of
               an
               Empyrical
               Remedy
               ,
               which
               is
               mention'd
               in
               another
               Paper
               ,
               whose
               success
               I
               neither
               would
               warrant
               ,
               nor
               did
               altogether
               dispair
               of
               ,
               and
               which
               at
               least
               seem'd
               safe
               ,
               tho'
               it
               should
               not
               prove
               effectual
               .
               This
               was
               only
               a
               simple
               substance
               ,
               (
               belonging
               to
               the
               Animal
               Kingdom
               )
               that
               was
               to
               be
               worn
               in
               a
               sine
               Sarsanet
               Bag
               between
               the
               Shift
               and
               the
               Skin
               ,
               for
               which
               a
               good
               while
               after
               the
               Physician
               gave
               me
               great
               thanks
               ,
               telling
               me
               ,
               that
               he
               was
               surpriz'd
               at
               the
               effect
               of
               it
               ,
               and
               that
               he
               observ'd
               that
               when
               the
               Patient
               had
               worn
               it
               so
               long
               ,
               that
               probably
               the
               vertue
               began
               to
               decay
               ,
               that
               is
               in
               my
               sense
               ,
               that
               the
               Effluvia
               were
               almost
               spent
               ,
               the
               Patient
               found
               need
               to
               take
               a
               fresh
               Remedy
               ,
               to
               continue
               the
               benefit
               she
               had
               found
               by
               the
               former
               .
            
             
               I
               do
               not
               affirm
               or
               expect
               ,
               that
               the
               three
               fornam'd
               Appensa
               ,
               nor
               the
               other
               Remedy's
               I
               am
               about
               to
               mention
               ,
               will
               always
               succeed
               .
               And
               I
               
               think
               ,
               one
               may
               assign
               some
               not
               improbable
               reasons
               of
               the
               want
               of
               uniformity
               in
               their
               effects
               .
               But
               for
               my
               present
               argument
               ,
               it
               suffices
               that
               they
               do
               sometimes
               succeed
               ,
               since
               that
               is
               enough
               to
               show
               it
               possible
               ,
               that
               outward
               Medicines
               may
               operate
               upon
               inward
               Distempers
               .
            
             
               Having
               one
               day
               given
               a
               visit
               to
               one
               of
               the
               skilfullest
               and
               candidest
               Physicians
               of
               the
               Famous
               Colledge
               of
               London
               ,
               I
               observ'd
               in
               his
               Chamber
               ,
               a
               fine
               new
               fashion'd
               Clock
               ;
               and
               having
               taken
               notice
               of
               it
               to
               him
               ,
               as
               a
               thing
               I
               had
               not
               seen
               there
               before
               ;
               he
               desir'd
               me
               not
               to
               think
               ,
               he
               was
               rich
               and
               vain
               enough
               to
               purchase
               ,
               so
               dear
               a
               rarity
               ;
               but
               that
               it
               belong'd
               to
               a
               Courtier
               whom
               he
               nam'd
               to
               me
               ,
               of
               whose
               Daughter
               he
               told
               me
               this
               story
               .
               This
               young
               Lady
               had
               a
               great
               Tumor
               in
               her
               Neck
               or
               Throat
               ,
               which
               being
               apprehended
               to
               be
               of
               a
               Scrophulous
               Nature
               ,
               made
               her
               Father
               fear
               it
               would
               oblige
               him
               to
               increase
               her
               Portion
               more
               than
               his
               Estate
               could
               conveniently
               bear
               .
               Wherefore
               at
               length
               
               he
               address'd
               himself
               to
               my
               Relator
               ,
               who
               judging
               the
               case
               to
               be
               difficult
               ,
               and
               being
               unwilling
               to
               torment
               the
               Lady
               with
               a
               long
               course
               of
               Physick
               ,
               told
               the
               Courteour
               ,
               that
               if
               he
               could
               animate
               her
               to
               suffer
               a
               Remedy
               he
               would
               propose
               ,
               and
               would
               assist
               him
               to
               procure
               it
               ,
               he
               hop'd
               to
               remove
               this
               Tumour
               without
               weakning
               her
               ,
               or
               putting
               her
               to
               pain
               .
               Soon
               after
               ,
               all
               Parties
               being
               agreed
               ,
               and
               the
               desired
               conveniency
               procur'd
               ,
               the
               Patient
               was
               brought
               into
               a
               Room
               ,
               where
               there
               was
               yet
               in
               Bed
               the
               Body
               of
               a
               man
               that
               had
               dy'd
               of
               a
               lingring
               Disease
               .
               This
               mans
               Hand
               the
               Doctor
               took
               ,
               and
               laid
               it
               upon
               his
               Patients
               Tumour
               ,
               keeping
               it
               there
               till
               she
               either
               complain'd
               or
               confess'd
               that
               she
               felt
               the
               coldness
               of
               it
               penetrate
               to
               the
               innermost
               Parts
               of
               her
               Tumour
               .
               This
               application
               was
               afterwards
               repeated
               more
               than
               once
               ,
               whilst
               the
               Body
               continued
               without
               smelling
               :
               And
               by
               this
               course
               the
               Tumour
               was
               dispell'd
               ,
               and
               the
               Patient
               so
               reliev'd
               ,
               that
               her
               Father
               ,
               by
               way
               of
               gratitude
               ,
               
               knowing
               how
               much
               the
               Physician
               was
               a
               lover
               of
               curiosities
               ,
               made
               him
               a
               present
               of
               that
               Clock
               .
            
             
               The
               Learned
               Doctor
               ascrib'd
               this
               odd
               Remedy
               to
               Helmont
               ,
               who
               is
               indeed
               to
               be
               thank'd
               for
               having
               mention'd
               and
               recommended
               a
               Medicine
               ,
               that
               was
               unlikely
               to
               be
               good
               ,
               besides
               that
               it
               was
               not
               in
               use
               .
               But
               the
               knowledge
               of
               it
               seems
               to
               me
               to
               have
               been
               for
               the
               main
               very
               much
               ancienter
               than
               our
               Age
               :
               since
               there
               is
               mention
               made
               of
               one
               very
               like
               it
               by
               so
               Ancient
               an
               Author
               as
               Pliny
               ;
               tho'
               since
               his
               time
               till
               Helmonts
               it
               hath
               been
               generally
               forgotten
               or
               disbeliev'd
               ,
               save
               that
               one
               Physician
               (
               
                 Franciscus
                 Ulmus
              
               )
               who
               ,
               tho'
               no
               ill
               Observer
               ,
               has
               not
               had
               the
               Fortune
               to
               be
               Famous
               ,
               takes
               notice
               of
               a
               case
               very
               like
               that
               of
               our
               Courtiers
               Daughter
               ,
               affirming
               ,
               that
               by
               that
               one
               Remedy
               ,
               after
               others
               had
               been
               fruitlesly
               imploy'd
               ,
               he
               knew
               a
               Noble
               Virgin
               to
               have
               been
               perfectly
               cur'd
               .
            
             
               I
               was
               one
               Summer
               ,
               to
               my
               great
               surprize
               obnoxious
               to
               frequent
               Bleedings
               
               at
               the
               Nose
               ;
               for
               which
               I
               sometimes
               us'd
               one
               Remedy
               ,
               and
               sometimes
               another
               ,
               for
               the
               most
               part
               with
               good
               ,
               but
               not
               still
               with
               quick
               success
               .
               But
               falling
               once
               unexpectedly
               into
               a
               Fit
               ,
               whose
               violence
               somewhat
               alarm'd
               me
               ,
               I
               resolv'd
               to
               try
               an
               unusual
               Remedy
               :
               And
               having
               easily
               obtain'd
               of
               my
               Sister
               ,
               in
               whose
               house
               this
               Accident
               happen'd
               ,
               some
               true
               Moss
               of
               a
               dead
               Mans
               Scull
               ,
               which
               had
               been
               sent
               her
               ,
               by
               a
               great
               Person
               ,
               for
               a
               present
               out
               of
               Ireland
               ,
               in
               which
               Country
               ,
               I
               found
               it
               less
               rare
               and
               more
               esteem'd
               than
               elsewhere
               :
               I
               was
               going
               to
               imploy
               it
               after
               the
               usual
               manner
               ,
               which
               is
               to
               put
               it
               up
               into
               the
               Patients
               Nostrils
               ,
               but
               before
               I
               did
               it
               ,
               I
               had
               the
               curiosity
               to
               try
               ,
               notwithstanding
               the
               briskness
               of
               my
               Haemorrhagy
               ,
               whether
               the
               Medicine
               would
               produce
               its
               effect
               by
               being
               only
               held
               in
               my
               Hand
               ,
               and
               therefore
               covering
               a
               piece
               of
               the
               Moss
               with
               my
               Fist
               ,
               that
               the
               warmth
               might
               a
               little
               actuate
               the
               Medicine
               ,
               I
               found
               ,
               to
               the
               wonder
               of
               the
               by-standers
               ,
               
               that
               the
               Blood
               speedily
               stopp'd
               ,
               nor
               thanks
               be
               to
               God
               have
               I
               been
               troubled
               with
               a
               Haemorrhagy
               for
               some
               years
               from
               that
               very
               time
               .
               But
               this
               is
               far
               less
               strange
               than
               what
               was
               affirm'd
               to
               have
               happen'd
               to
               one
               of
               the
               Eminentest
               Members
               of
               the
               Royal
               Society
               .
               This
               Learned
               Gentleman
               ,
               who
               was
               of
               a
               very
               Sanguine
               Complexion
               ,
               found
               himself
               much
               affected
               by
               the
               use
               of
               the
               Moss
               of
               a
               human
               Scull
               ,
               [
               pieces
               of
               which
               I
               have
               seen
               sticking
               to
               the
               Roots
               of
               the
               Vegetable
               ,
               when
               it
               was
               genuine
               ]
               which
               had
               so
               strange
               an
               operation
               upon
               him
               ,
               that
               sometimes
               when
               he
               was
               let
               Blood
               ,
               if
               for
               curiosities
               sake
               he
               held
               a
               quantity
               of
               this
               Moss
               in
               his
               Hand
               ,
               the
               Efflux
               of
               the
               Blood
               would
               cease
               ,
               till
               he
               laid
               it
               by
               again
               ;
               which
               was
               not
               only
               solemnly
               averr'd
               to
               me
               by
               himself
               ,
               but
               confirm'd
               to
               me
               by
               his
               Ingenious
               Physician
               ,
               with
               both
               whom
               I
               had
               a
               particular
               Acquaintance
               ;
               which
               otherwise
               I
               should
               have
               thought
               scarce
               credible
               ,
               unless
               imagination
               ,
               a
               faculty
               very
               strong
               in
               that
               Gentleman
               ,
               
               contributed
               to
               the
               strange
               effect
               of
               the
               Remedy
               .
            
             
               The
               hitherto
               mention'd
               External
               Specificks
               are
               afforded
               by
               Vegetables
               and
               Animals
               ,
               which
               being
               Bodies
               of
               a
               slighter
               Texture
               ,
               may
               be
               suppos'd
               to
               have
               their
               Parts
               more
               Effluviable
               :
               And
               therefore
               I
               shall
               now
               add
               two
               or
               three
               examples
               afforded
               by
               the
               Mineral
               Kingdom
               ,
               which
               consisting
               of
               Bodies
               that
               never
               were
               living
               ,
               and
               which
               are
               for
               the
               most
               part
               very
               close
               and
               compact
               ,
               are
               generally
               thought
               to
               have
               their
               Parts
               indispos'd
               to
               emit
               Effluvia
               .
            
             
               I
               knew
               a
               Person
               of
               great
               Learning
               ,
               and
               by
               Profession
               a
               Physician
               ,
               who
               enjoy'd
               a
               Health
               good
               enough
               ,
               save
               that
               usually
               after
               a
               few
               hours
               sleep
               ,
               he
               wak'd
               in
               the
               Night
               with
               great
               Terrors
               ,
               follow'd
               for
               a
               long
               time
               with
               such
               violent
               Palpitations
               of
               the
               Heart
               ,
               as
               were
               very
               troublesom
               ,
               and
               sometimes
               frightful
               to
               him
               .
               To
               remove
               this
               Distemper
               ,
               he
               try'd
               all
               that
               his
               Art
               suggested
               to
               him
               ,
               but
               without
               success
               ,
               Whereupon
               he
               complain'd
               
               of
               it
               to
               several
               of
               his
               Acquaintance
               ;
               and
               mentioning
               it
               one
               day
               among
               a
               Company
               of
               Merchants
               ,
               whereof
               some
               frequented
               very
               remote
               Country's
               ;
               one
               of
               them
               told
               him
               ,
               he
               would
               easily
               relieve
               him
               ,
               by
               a
               Remedy
               that
               had
               been
               found
               efficacious
               both
               upon
               himself
               and
               others
               .
               This
               he
               told
               him
               was
               ,
               to
               take
               divers
               flat
               and
               smooth
               Cornelian
               Stones
               ,
               such
               as
               they
               bring
               from
               the
               East-Indies
               ,
               to
               cut
               Rings
               out
               of
               ,
               and
               to
               sow
               eight
               or
               ten
               of
               them
               to
               a
               piece
               of
               Scarlet
               or
               Flannel
               ,
               to
               be
               hung
               about
               his
               Neck
               ,
               so
               as
               that
               the
               Stones
               may
               immediately
               touch
               the
               Skin
               over
               against
               the
               Heart
               ,
               and
               the
               Mouth
               of
               the
               Stomach
               .
               This
               Remedy
               the
               Physician
               procur'd
               ,
               and
               in
               no
               long
               time
               ,
               found
               the
               great
               benefit
               of
               it
               ,
               insomuch
               that
               he
               thought
               he
               might
               now
               securely
               leave
               off
               the
               use
               of
               these
               Stones
               ,
               which
               he
               did
               once
               or
               twice
               out
               of
               curiosity
               ,
               as
               well
               as
               for
               his
               ease
               ,
               but
               finding
               the
               Distemper
               to
               return
               each
               time
               ,
               within
               very
               few
               Weeks
               after
               he
               had
               laid
               aside
               his
               Remedy
               ,
               he
               resolv'd
               
               to
               keep
               it
               always
               on
               ,
               as
               he
               had
               long
               successfully
               done
               ,
               when
               he
               told
               me
               the
               story
               .
               And
               to
               convince
               me
               ,
               presented
               me
               with
               some
               of
               the
               Cornelians
               ,
               that
               he
               had
               ,
               for
               fear
               of
               wanting
               them
               ,
               procur'd
               in
               greater
               number
               than
               he
               needed
               at
               once
               .
               But
               since
               I
               have
               not
               yet
               had
               occasion
               to
               make
               tryal
               of
               them
               ,
               I
               shall
               not
               conclude
               that
               the
               Remedy
               will
               always
               succeed
               ,
               but
               only
               (
               which
               is
               enough
               for
               my
               present
               purpose
               )
               that
               't
               is
               at
               least
               possible
               that
               such
               an
               External
               Remedy
               may
               be
               very
               effectual
               .
            
             
               I
               afterwards
               thought
               (
               which
               I
               here
               note
               ,
               to
               add
               to
               the
               probability
               of
               what
               I
               have
               been
               relating
               )
               that
               pos
               ;
               sibly
               those
               that
               first
               made
               use
               of
               the
               foremention'd
               Remedy
               ,
               may
               have
               had
               a
               hint
               from
               what
               Galen
               saith
               of
               the
               Jasper
               :
               Which
               Stone
               we
               observe
               to
               be
               various
               in
               point
               of
               Colour
               ,
               and
               I
               have
               seen
               in
               the
               green
               mixtures
               of
               Red
               almost
               as
               deep
               as
               that
               of
               Cornelians
               .
               Of
               this
               Stone
               Galen
               relates
               that
               some
               made
               Rings
               ,
               in
               which
               were
               graven
               a
               Dragon
               having
               Beams
               
               issuing
               from
               him
               ,
               and
               commended
               it
               as
               very
               friendly
               to
               the
               Stomach
               ,
               being
               apply'd
               to
               the
               Mouth
               of
               it
               .
               And
               tho'
               he
               omitted
               (
               and
               found
               he
               safely
               might
               do
               it
               )
               the
               Sculpture
               ,
               he
               yet
               approves
               the
               Stones
               upon
               his
               own
               frequent
               experience
               ,
               applying
               them
               almost
               as
               our
               Merchant
               did
               ;
               
               
                 Sane
                 hujus
              
               (
               says
               he
               )
               
                 ego
                 quo
                 lapidis
                 abunde
                 feci
                 periculum
                 Torquem
                 enim
                 ex
                 hujusmodi
                 lapillis
                 confectum
                 collo
                 suspendi
                 ita
                 ut
                 lapides
                 os
                 ventriculi
                 contingerent
                 apparebant
                 ,
                 autem
                 nihilominus
                 prodesse
                 etiamsi
                 sculpturam
                 non
                 haberent
                 ,
              
               &c.
               
            
             
               I
               have
               lately
               mention'd
               the
               efficacy
               of
               a
               Cramp
               Ring
               upon
               some
               Parts
               of
               the
               
                 Genus
                 Nervosum
              
               .
               But
               some
               will
               perhaps
               think
               it
               more
               considerable
               ,
               if
               a
               Stone
               Ring
               worn
               on
               the
               Finger
               shall
               be
               able
               to
               work
               upon
               the
               Mass
               of
               Blood
               ,
               and
               particularly
               that
               deprav'd
               Portion
               of
               it
               ,
               that
               Nature
               relegates
               to
               such
               distant
               Parts
               as
               the
               Hemorrhoidal
               Veins
               .
               And
               yet
               the
               experienc'd
               Monardes
               ,
               having
               desrib'd
               
               the
               Blood-Stone
               that
               is
               brought
               from
               New
               -
               Spain
               ,
               and
               represented
               it
               as
               a
               Jasper
               ,
               not
               only
               commends
               it
               against
               Hemorrhages
               ,
               being
               applyed
               to
               the
               Bleeding
               Part
               ,
               
               but
               adds
               the
               following
               words
               ,
               which
               declare
               that
               he
               speaks
               upon
               experience
               ,
               
                 Vidimus
                 nonnullos
                 Haemorrhoidum
                 Fluxu
                 afflictos
                 Remedium
                 sensisse
                 ,
                 Annulos
                 ex
                 hoc
                 Lapide
                 confectos
                 in
                 Digito
                 continue
                 gestando
                 :
                 nec
                 non
                 &
                 Menstruum
                 Fluxum
                 sisti
                 .
              
            
             
               I
               know
               you
               will
               expect
               here
               ,
               that
               I
               should
               not
               on
               this
               occasion
               pretermit
               the
               
                 Lapis
                 Nephriticus
              
               ;
               of
               which
               sort
               of
               Stones
               ,
               tho'
               many
               have
               been
               found
               ineffectual
               against
               the
               Disease
               that
               gives
               them
               their
               name
               ,
               and
               tho'
               it
               be
               scarce
               possible
               to
               choose
               those
               few
               that
               are
               good
               ,
               without
               having
               particularly
               and
               actually
               try'd
               them
               ;
               yet
               that
               some
               of
               them
               are
               of
               great
               virtue
               ,
               we
               have
               the
               Testimony
               of
               the
               inquisitive
               and
               judicious
               Boetius
               ,
               and
               that
               other
               Learned
               Writer
               about
               Gems
               
                 Johannes
                 de
                 Laet
              
               ,
               whose
               Praises
               
               are
               confirm'd
               by
               the
               Historical
               Testimonies
               of
               Monardes
               and
               others
               .
               But
               none
               that
               I
               have
               met
               speaks
               more
               home
               to
               our
               purpose
               than
               a
               considerable
               Merchant
               of
               Leipsick
               ,
               whose
               rare
               Observations
               are
               recorded
               by
               a
               man
               of
               very
               great
               reading
               the
               Learned
               *
               Untzerus
               ,
               to
               whom
               I
               refer
               you
               ,
               contenting
               my self
               to
               mention
               in
               this
               place
               two
               of
               the
               ten
               Remarks
               he
               sets
               down
               ,
               the
               first
               ,
               that
               the
               Merchant
               affirm'd
               to
               our
               Author
               ,
               that
               by
               wearing
               this
               Stone
               for
               some
               days
               ,
               the
               calculous
               matter
               was
               so
               powerfully
               proscrib'd
               ,
               that
               a
               multitude
               of
               small
               grains
               of
               Sand
               were
               expell'd
               ,
               even
               at
               the
               corners
               of
               his
               Eyes
               .
               The
               like
               effect
               ,
               to
               which
               he
               often
               observ'd
               of
               that
               Remedy
               in
               divers
               other
               Persons
               .
               The
               second
               ,
               that
               by
               wearing
               the
               same
               Stone
               ,
               his
               Wife
               who
               was
               troubled
               with
               a
               great
               Catarrh
               found
               it
               considerably
               Cathartick
               ,
               insomuch
               that
               the
               first
               day
               she
               was
               thereby
               purg'd
               fourteen
               or
               fifteen
               times
               ,
               the
               next
               nine
               or
               ten
               times
               ,
               and
               afterwards
               
               had
               her
               Body
               kept
               very
               open
               .
               And
               he
               adds
               ,
               that
               he
               found
               also
               this
               Stone
               to
               operate
               like
               a
               Purge
               ,
               tho'
               not
               so
               strongly
               upon
               himself
               .
            
             
               But
               enough
               ,
               if
               not
               more
               than
               enough
               ,
               of
               the
               vertues
               of
               Periapta
               and
               Appensa
               especially
               ,
               since
               more
               instances
               of
               them
               may
               be
               met
               with
               in
               some
               other
               Papers
               :
               And
               even
               without
               them
               ,
               or
               at
               least
               with
               them
               ,
               those
               particulars
               I
               come
               from
               mentioning
               ,
               may
               furnish
               a
               sufficient
               Answer
               to
               the
               Objection
               that
               has
               occasion'd
               them
               .
            
          
           
             
               The
               Conclusion
               .
            
             
               And
               now
               ,
               Sir
               ,
               you
               have
               what
               the
               consideration
               of
               the
               Nature
               of
               the
               things
               I
               treat
               of
               suggested
               to
               me
               ,
               about
               the
               Principal
               ways
               ,
               by
               which
               I
               conceive
               Specifick
               Medicines
               may
               cure
               Diseases
               ,
               or
               at
               least
               much
               lessen
               them
               .
               I
               said
               the
               
                 Principal
                 ways
              
               ,
               because
               I
               am
               far
               from
               denying
               ,
               that
               there
               may
               be
               many
               others
               ,
               that
               must
               
               not
               here
               be
               mention'd
               ,
               lest
               I
               should
               too
               much
               transgress
               the
               limits
               that
               become
               an
               Epistle
               ;
               especially
               ,
               this
               being
               already
               far
               more
               prolix
               than
               I
               at
               first
               intended
               ;
               though
               I
               purposely
               omitted
               the
               Authorities
               and
               Arguments
               of
               divers
               Physicians
               and
               Chymists
               ,
               that
               maintain
               that
               there
               are
               Specifick
               Medicines
               ,
               bccause
               they
               proceed
               upon
               Principles
               ,
               (
               such
               as
               substantial
               Forms
               ,
               real
               Qualities
               ,
               Ideas
               ,
               or
               Chaoses
               and
               the
               like
               ,
               )
               which
               I
               could
               not
               fairly
               employ
               ,
               because
               I
               do
               not
               admit
               them
               .
               But
               though
               I
               forbore
               to
               lengthen
               my
               discourse
               ,
               by
               improper
               ,
               and
               I
               hope
               needless
               Transcriptions
               out
               of
               others
               ;
               yet
               't
               is
               long
               enough
               to
               prompt
               me
               ,
               now
               at
               the
               close
               of
               it
               to
               remind
               you
               of
               two
               or
               three
               things
               that
               I
               declar'd
               at
               the
               beginning
               .
            
             
               As
               First
               ,
               that
               I
               did
               not
               pretend
               that
               a
               Specifick
               Medicine
               ,
               or
               Nature
               by
               a
               Specifick
               ,
               does
               commonly
               effect
               the
               cure
               by
               one
               of
               the
               particular
               ways
               that
               I
               propos'd
               ,
               exclusively
               to
               the
               rest
               ;
               since
               I
               rather
               think
               that
               oftentimes
               
               two
               ,
               and
               sometimes
               more
               ,
               concur
               to
               the
               effect
               .
               Secondly
               ,
               that
               I
               propos'd
               to
               my self
               ,
               to
               explicate
               the
               ways
               of
               working
               of
               Specifick
               Remedies
               ,
               only
               in
               general
               .
               And
               Thirdly
               ,
               that
               I
               did
               not
               assert
               ,
               that
               the
               ways
               I
               pitch'd
               upon
               were
               the
               true
               and
               genuine
               ones
               ,
               by
               which
               the
               Medicine
               does
               act
               ,
               but
               only
               propounded
               them
               ,
               as
               ways
               by
               which
               it
               may
               act
               :
               So
               that
               without
               being
               Dogmatical
               ,
               I
               offer
               you
               my
               Explications
               ,
               but
               as
               possible
               ,
               and
               perhaps
               not
               improbable
               ;
               and
               that
               may
               suffice
               for
               the
               occasion
               and
               scope
               of
               this
               Letter
               ;
               in
               which
               I
               presume
               ,
               you
               remember
               I
               aim'd
               but
               at
               shewing
               you
               ,
               that
               the
               operations
               of
               Specifick
               Medicines
               
                 are
                 not
                 irreconcileable
              
               to
               the
               Principles
               of
               the
               Corpuscular
               Philosophy
               :
               Which
               I
               hope
               you
               will
               without
               reluctancy
               grant
               ,
               if
               ,
               by
               my
               good
               Fortune
               ,
               the
               difficulties
               that
               made
               you
               hesitate
               ,
               seem
               to
               you
               to
               be
               lessen'd
               by
               so
               barren
               an
               intellect
               as
               mine
               ,
               discoursing
               of
               an
               abftruce
               subject
               ,
               which
               belongs
               to
               a
               prosession
               that
               I
               am
               not
               of
               .
               Upon
               which
               account
               
               it
               may
               be
               justly
               presum'd
               ,
               that
               you
               ,
               who
               have
               so
               much
               more
               sagacity
               ,
               and
               are
               so
               much
               more
               concern'd
               than
               I
               in
               the
               subject
               I
               have
               been
               treating
               of
               ;
               and
               who
               being
               a
               profess'd
               Physician
               ,
               have
               much
               more
               opportunity
               to
               discover
               the
               various
               courses
               that
               Nature
               does
               or
               may
               take
               in
               curing
               Diseases
               ;
               will
               be
               able
               to
               give
               your self
               far
               more
               satisfaction
               ,
               than
               you
               could
               hope
               to
               receive
               from
               me
               ,
               who
               have
               therefore
               propos'd
               to
               you
               my
               conjectures
               very
               diffidently
               ,
               tho'
               I
               am
               very
               poisitive
               in
               asserting
               my self
               to
               be
            
             
               
                 SIR
                 ,
              
               
                 Your
                 most
                 ,
                 &c.
                 
                 ROBERT
                 BOYLE
                 .
              
            
          
        
      
       
         
           
           
             THE
             ADVANTAGES
             Of
             the
             Use
             of
             SIMPLE
             MEDICINES
             .
          
           
             Propos'd
             by
             way
             of
             INVITATION
             To
             it
             .
          
           
             By
             the
             Honourable
             
               ROBERT
               BOLE
            
             Fellow
             of
             the
             Royal
             Society
             .
          
        
         
           
           
           
             AN
             INVITATION
             To
             the
             Use
             of
             Simple
             Medicines
             .
          
           
             To
             the
             very
             Learned
             Dr.
             F.
             
          
           
             
               §I
               .
            
             
               
                 SIR
                 ,
              
            
             
               Since
               
                 SPECIFICK
                 MEDICINES
              
               ,
               to
               deserve
               that
               name
               ,
               must
               be
               very
               Efficacious
               ;
               and
               yet
               are
               for
               the
               most
               part
               either
               simple
               or
               very
               little
               compounded
               ,
               what
               has
               been
               said
               about
               them
               in
               the
               foregoing
               Tract
               concerning
               Specificks
               may
               afford
               me
               a
               not
               improper
               rise
               to
               invite
               you
               ,
               and
               thereby
               others
               of
               your
               Profession
               ,
               on
               
               whom
               your
               Authority
               and
               Example
               may
               justly
               have
               much
               influence
               ,
               to
               seek
               after
               and
               Imploy
               ,
               more
               than
               they
               are
               wont
               to
               do
               ,
               such
               Remedies
               as
               are
               either
               simple
               ,
               or
               ,
               when
               there
               happens
               a
               necessity
               to
               compound
               ,
               are
               made
               up
               of
               no
               more
               Ingredients
               than
               are
               absolutely
               requisite
               to
               answer
               the
               Indications
               ,
               and
               the
               Physicians
               Scope
               .
            
             
               This
               sort
               of
               simple
               ,
               or
               but
               lightly
               Compounded
               ,
               Remedies
               ,
               I
               am
               induc'd
               to
               prefer
               before
               those
               pompous
               compositions
               ,
               wherein
               men
               seem
               to
               have
               hop'd
               to
               surmount
               diseases
               by
               the
               multitude
               of
               the
               Ingredients
               ,
               upon
               the
               following
               Reasons
               .
               In
               all
               which
               I
               desire
               the
               advantages
               ascrib'd
               to
               simple
               Medicines
               ,
               above
               others
               may
               be
               understood
               ,
               not
               in
               an
               absolute
               and
               indefinite
               sense
               ,
               but
               ,
               as
               they
               speak
               
                 caeteris
                 paribus
              
               ,
               which
               I
               here
               give
               you
               notice
               of
               once
               for
               all
            
             
               And
               the
               first
               advantage
               that
               I
               shall
               mention
               ,
               is
               ,
               That
               it
               is
               much
               less
               difficult
               ,
               to
               foresee
               the
               operation
               of
               a
               
               simple
               ,
               than
               of
               a
               very
               compounded
               Medicine
               .
               So
               that
               Physicians
               may
               proceed
               more
               securely
               ,
               in
               imploying
               the
               former
               than
               the
               latter
               sort
               of
               Remedies
               .
               And
               indeed
               ,
               if
               I
               do
               not
               greatly
               mistake
               ,
               we
               often
               presume
               too
               much
               of
               our
               own
               Abilities
               when
               we
               believe
               that
               we
               know
               before
               hand
               ,
               what
               the
               Qualities
               and
               Effects
               of
               a
               Mixture
               of
               many
               Ingredients
               of
               differing
               Natures
               ,
               will
               be
               :
               Since
               many
               Bodies
               ,
               by
               Composition
               ,
               and
               the
               change
               of
               Texture
               consequent
               thereupon
               ,
               do
               receive
               great
               and
               unexpected
               Alterations
               in
               their
               Qualities
               .
               Several
               manifest
               Instances
               of
               this
               Truth
               may
               be
               met
               with
               in
               our
               History
               of
               Colours
               ;
               In
               divers
               of
               whose
               Experiments
               ,
               the
               Colour
               produc'd
               upon
               the
               Mixture
               of
               Bodies
               ,
               is
               quite
               different
               from
               that
               of
               any
               of
               the
               Ingredients
               .
               As
               ,
               when
               a
               blew
               Solution
               of
               Copper
               made
               in
               Spirit
               of
               Urine
               ,
               does
               with
               Syrup
               of
               Violets
               ,
               which
               is
               also
               blew
               ,
               produce
               a
               fair
               Green.
               And
               even
               since
               I
               began
               to
               write
               this
               Section
               ,
               a
               Tryal
               purposely
               
               made
               has
               afforded
               me
               a
               new
               Instance
               of
               the
               same
               import
               .
            
             
               For
               having
               put
               together
               some
               Tincture
               of
               Iron
               ,
               made
               with
               good
               Spirit
               of
               Vinegar
               ,
               and
               a
               Volatile
               Tincture
               of
               Sulphur
               ,
               (
               which
               I
               elsewhere
               show
               how
               to
               make
               )
               from
               a
               Confusion
               of
               these
               two
               very
               red
               Liquors
               ,
               there
               emerg'd
               in
               a
               trice
               ,
               a
               very
               dark
               and
               almost
               Inky
               Mixture
               ,
               that
               retain'd
               nothing
               at
               all
               of
               Redness
               .
            
             
               The
               like
               notable
               changes
               I
               have
               several
               times
               produc'd
               by
               Mixtures
               ,
               in
               divers
               other
               Qualities
               of
               Bodies
               than
               their
               Colours
               ,
               as
               in
               their
               Odours
               ,
               Tasts
               ,
               &c.
               
               And
               why
               such
               Alterations
               may
               not
               be
               also
               effected
               by
               Composition
               ,
               in
               some
               of
               the
               Medicinal
               Qualities
               of
               Bodies
               ,
               I
               do
               not
               yet
               see
               .
               Quick-silver
               it self
               inwardly
               taken
               ,
               does
               usually
               cause
               ,
               either
               no
               manifest
               evacuation
               ,
               or
               one
               that
               is
               made
               at
               the
               mouth
               :
               But
               if
               it
               be
               dissolv'd
               in
               Spirit
               of
               Niter
               ,
               and
               Precipitated
               with
               Sea-Salt
               ,
               this
               white
               Precipitate
               being
               edulcorated
               ,
               if
               it
               
               be
               warily
               given
               in
               a
               just
               Dose
               ,
               doth
               (
               as
               far
               as
               I
               can
               yet
               learn
               )
               seldom
               fail
               of
               working
               ,
               and
               yet
               seldomer
               work
               by
               Salivation
               ,
               but
               by
               Siege
               .
               On
               the
               other
               side
               Glass
               of
               Antimony
               (
               made
               
                 per
                 se
              
               )
               whereof
               a
               very
               few
               Grains
               given
               in
               substance
               ,
               are
               wont
               to
               work
               violently
               upwards
               and
               downwards
               ,
               being
               dissolved
               in
               Spirit
               of
               Vinegar
               ,
               (
               which
               is
               not
               easily
               and
               quickly
               done
               )
               will
               not
               usually
               either
               Vomit
               or
               Purge
               ,
               tho
               the
               Menstruum
               be
               drawn
               from
               it
               ,
               and
               tho
               it
               be
               given
               in
               a
               larger
               Dose
               ,
               than
               that
               of
               the
               uncompounded
               Glass
               .
            
             
               And
               tho
               if
               Crude
               Antimony
               be
               flux'd
               with
               Niter
               and
               Tartar
               ,
               as
               in
               the
               ordinary
               way
               of
               making
               
                 Crocus
                 Metallorum
              
               ,
               there
               is
               produc'd
               ,
               as
               is
               vulgarly
               known
               ,
               a
               Medicine
               so
               Emetick
               and
               Cathartick
               ,
               that
               an
               Ounce
               or
               less
               of
               the
               Wine
               wherein
               it
               has
               been
               infus'd
               ,
               without
               sensibly
               loosing
               its
               weight
               ,
               is
               wont
               to
               work
               strongly
               enough
               both
               upwards
               and
               downwards
               :
               Yet
               I
               have
               known
               some
               that
               would
               without
               scruple
               ,
               take
               
               several
               Grains
               of
               Crude
               Antimony
               in
               substance
               ,
               and
               one
               particularly
               that
               continued
               the
               use
               of
               it
               long
               ,
               without
               being
               vomited
               or
               purg'd
               by
               it
               .
               And
               Tryals
               purposely
               made
               have
               inform'd
               me
               ,
               that
               if
               ,
               instead
               of
               Salt-Peter
               and
               Tartar
               ,
               Antimony
               be
               prepar'd
               with
               well
               dry'd
               Sea-Salt
               ,
               and
               a
               little
               Salt
               of
               Tartar
               ,
               tho
               both
               ,
               these
               amount
               not
               to
               above
               half
               the
               weight
               of
               the
               Niter
               and
               Tartar
               vulgarly
               us'd
               ,
               yet
               the
               Antimony
               well
               flux'd
               with
               these
               (
               for
               about
               an
               hour
               )
               is
               thereby
               so
               alter'd
               and
               corrected
               ,
               that
               it
               affords
               an
               useful
               Medicine
               ,
               of
               which
               one
               may
               give
               from
               12
               or
               15
               Grains
               to
               half
               a
               Dram
               ,
               or
               more
               in
               substance
               ,
               without
               ordinarily
               working
               ,
               either
               by
               Vomit
               or
               Siege
               ,
               but
               usually
               by
               Sweat
               ,
               and
               sometimes
               by
               Urine
               .
               Whence
               we
               may
               gather
               ,
               that
               Antimony
               may
               be
               either
               made
               a
               more
               dangerous
               ,
               or
               a
               more
               friendly
               Medicine
               ,
               than
               of
               it self
               it
               is
               ,
               according
               to
               the
               Ingredients
               't
               is
               associated
               with
               ,
               tho
               these
               be
               in
               themselves
               Innocent
               ,
               and
               perhaps
               of
               kin
               to
               one
               
               another
               .
               And
               even
               Chymists
               ,
               as
               well
               as
               other
               prescribers
               of
               Remedies
               ,
               may
               be
               found
               ,
               tho
               less
               frequently
               ,
               to
               add
               to
               a
               Simple
               ,
               such
               things
               as
               rather
               deprave
               ,
               than
               improve
               it
               .
               As
               one
               of
               their
               great
               Patrons
               (
               a
               happy
               Practitioner
               )
               complains
               ,
               that
               Flower
               of
               Sulphur
               ,
               by
               being
               sublim'd
               ,
               (
               as
               by
               many
               it
               is
               )
               from
               Calcin'd
               Vitriol
               ,
               and
               one
               or
               two
               other
               things
               ,
               under
               pretence
               of
               purifying
               and
               subtillizing
               it
               ,
               does
               really
               acquire
               a
               hurtful
               Corrosiveness
               .
               And
               if
               I
               had
               here
               the
               Leizure
               ,
               Instances
               enough
               might
               be
               brought
               to
               show
               ,
               that
               Chymists
               sometimes
               mistakingly
               produce
               by
               their
               additions
               to
               a
               Medicine
               ,
               other
               Qualities
               ,
               if
               not
               also
               worse
               ,
               than
               they
               design'd
               or
               expected
               .
            
          
           
             
             
               §
               II.
               
            
             
               ANother
               Advantage
               of
               Simpler
               Medicines
               ,
               is
               ,
               that
               
                 caeteris
                 paribus
              
               ,
               they
               are
               more
               safe
               than
               compounded
               ones
               ,
               especially
               if
               the
               Patients
               be
               valetudinary
               persons
               .
               'T
               is
               too
               much
               the
               custom
               ,
               both
               of
               many
               Herbarists
               ,
               and
               several
               other
               Writers
               on
               the
               
                 Materia
                 Medica
              
               ,
               to
               give
               us
               rather
               Encomiums
               than
               impartial
               Accounts
               of
               the
               Simples
               they
               treat
               of
               ;
               enumerating
               and
               magnifying
               all
               the
               vertues
               they
               have
               ,
               and
               sometimes
               more
               than
               they
               have
               ,
               without
               taking
               notice
               of
               their
               ill
               Qualities
               ,
               upon
               whose
               account
               nevertheless
               they
               may
               be
               inconvenient
               ,
               if
               not
               hurtful
               and
               dangerous
               ,
               to
               some
               Constitutions
               ,
               and
               in
               divers
               Cases
               .
               We
               know
               that
               divers
               Perfumes
               ,
               as
               Musk
               and
               Amber
               ,
               tho
               very
               grateful
               and
               refreshing
               to
               most
               Mens
               Spirits
               ,
               are
               yet
               very
               hurtful
               to
               many
               Women
               ,
               and
               especially
               to
               those
               that
               
               are
               Hysterical
               .
               And
               I
               have
               known
               the
               smell
               of
               Musk
               very
               much
               disaffect
               an
               eminent
               Person
               ,
               though
               otherwise
               of
               a
               robust
               Constitution
               .
               I
               have
               also
               known
               several
               Persons
               ,
               not
               all
               of
               them
               of
               the
               same
               Sex
               ,
               very
               much
               offended
               by
               the
               smell
               of
               Roses
               ,
               which
               yet
               is
               very
               moderate
               ,
               as
               well
               as
               to
               most
               Persons
               ,
               whether
               Men
               or
               Women
               ,
               very
               grateful
               .
               I
               know
               a
               very
               great
               Person
               to
               whom
               Honey
               ,
               whether
               inwardly
               taken
               ,
               or
               outwardly
               apply'd
               ,
               is
               almost
               as
               hurtful
               as
               Poyson
               ,
               having
               several
               times
               produc'd
               strange
               and
               frightful
               Symptoms
               ,
               even
               when
               the
               Patient
               knew
               not
               that
               any
               Honey
               had
               been
               imploy'd
               ,
               and
               consequently
               could
               not
               be
               thus
               oddly
               distemper'd
               by
               the
               force
               of
               Imagination
               .
               I
               think
               I
               have
               elsewhere
               taken
               notice
               of
               the
               harm
               ,
               that
               both
               I
               and
               others
               ,
               subject
               to
               Diseases
               of
               the
               Eyes
               ,
               have
               receiv'd
               ,
               even
               by
               the
               moderate
               use
               of
               Parsley
               .
            
             
               On
               this
               occasion
               I
               shall
               add
               what
               occurr'd
               to
               me
               long
               after
               I
               had
               dictated
               what
               I
               said
               of
               Parsley
               ,
               that
               
               Worm-wood
               ,
               tho
               for
               many
               uses
               ,
               an
               excellent
               Plant
               ,
               has
               been
               found
               by
               many
               so
               apt
               to
               disaffect
               the
               head
               ,
               and
               so
               unfriendly
               to
               the
               Eyes
               ,
               that
               I
               have
               for
               some
               years
               forborn
               it
               my self
               for
               fear
               of
               the
               head-ach
               ,
               and
               forewarn'd
               others
               of
               it
               that
               are
               subject
               to
               weak
               Eyes
               .
               But
               I
               know
               a
               very
               Learned
               Man
               ,
               whose
               Elegant
               Pen
               has
               made
               him
               deservedly
               be
               taken
               notice
               of
               by
               many
               ,
               who
               ,
               tho
               he
               have
               naturally
               very
               good
               Eyes
               ,
               found
               upon
               an
               Obstinate
               Tryal
               ,
               that
               his
               Curiosity
               seduced
               him
               to
               make
               of
               the
               plentiful
               use
               of
               Worm-wood-Wine
               and
               Beer
               ,
               that
               within
               less
               than
               three
               Weeks
               ,
               his
               sight
               was
               by
               degrees
               brought
               to
               be
               so
               weak
               ,
               that
               he
               could
               not
               read
               a
               Gazet
               without
               Spectacles
               ;
               but
               by
               totally
               leaving
               off
               Worm-wood
               ,
               he
               quickly
               recover'd
               the
               vigour
               of
               his
               sight
               ,
               without
               the
               use
               of
               any
               of
               the
               helps
               that
               his
               profession
               ,
               which
               is
               Physick
               ,
               would
               have
               plentifully
               suggested
               to
               him
               .
               this
               Relation
               I
               had
               from
               himself
               soon
               after
               the
               thing
               happen'd
               ,
               on
               
               occasion
               of
               what
               I
               told
               him
               about
               Parsley
               ,
               &c.
               
            
             
               And
               to
               speak
               more
               generally
               ,
               I
               doubt
               not
               ,
               but
               if
               Men
               were
               not
               so
               prepossess'd
               with
               the
               Praises
               that
               Authors
               give
               to
               Simples
               ,
               that
               they
               overlook
               the
               Inconveniencies
               they
               may
               on
               divers
               occasions
               produce
               ,
               we
               should
               find
               in
               many
               Medicines
               bad
               Qualities
               ,
               that
               are
               not
               yet
               taken
               notice
               of
               .
               And
               I
               have
               more
               than
               once
               hit
               ,
               but
               too
               well
               ,
               in
               the
               Prognosticks
               I
               made
               of
               the
               Hurt
               ,
               some
               Patients
               would
               receive
               by
               the
               use
               of
               applauded
               Medicines
               ,
               prescribe
               them
               ,
               even
               by
               considerable
               and
               Learn'd
               Men
               ,
               when
               upon
               their
               Authority
               my
               warnings
               were
               neglected
               ,
               and
               the
               use
               of
               the
               Medicines
               unhappily
               persisted
               in
               .
               I
               remember
               I
               once
               saw
               in
               the
               hands
               of
               a
               learned
               and
               curious
               Traveller
               into
               the
               Eastern
               Parts
               of
               the
               World
               ,
               an
               Arabick
               Manuscript
               about
               the
               
                 Materia
                 Mèdica
              
               ,
               which
               made
               me
               regret
               the
               loss
               of
               the
               most
               part
               of
               the
               little
               skill
               I
               once
               had
               in
               
               that
               Language
               .
               For
               besides
               that
               it
               was
               written
               in
               a
               delicate
               hand
               ,
               and
               the
               Letters
               in
               fit
               Places
               ,
               curiously
               adorn'd
               with
               Gold
               and
               Azure
               ,
               the
               Method
               seem'd
               to
               be
               more
               accurate
               than
               any
               thing
               I
               had
               seen
               on
               that
               Subject
               .
               And
               that
               which
               pleas'd
               me
               not
               a
               little
               ,
               was
               ,
               that
               the
               Author
               had
               been
               so
               wary
               ,
               that
               after
               the
               columns
               wherein
               he
               taught
               ,
               besides
               many
               other
               things
               ,
               the
               Vertues
               ,
               Doses
               ,
               &c.
               of
               every
               Drug
               he
               treated
               of
               ,
               he
               had
               a
               distinct
               column
               for
               the
               bad
               Qualities
               of
               it
               ,
               and
               the
               constitutions
               and
               Diseases
               wherein
               the
               use
               of
               it
               may
               be
               dangerous
               or
               inconvenient
               .
               I
               think
               it
               therefore
               not
               unreasonable
               to
               suspect
               ,
               that
               ,
               where
               a
               great
               many
               Ingredients
               are
               blended
               into
               one
               Medicine
               ,
               one
               or
               other
               of
               them
               may
               have
               other
               operations
               ,
               besides
               that
               design'd
               by
               the
               Physician
               ;
               it
               may
               awaken
               some
               sleeping
               Ferment
               ,
               and
               ,
               if
               not
               produce
               a
               new
               Distemper
               ,
               may
               excite
               and
               actuate
               some
               other
               hostile
               matter
               ,
               that
               lay
               quiet
               in
               the
               Body
               before
               ,
               
               and
               perhaps
               would
               have
               been
               little
               by
               little
               subdu'd
               by
               nature
               ,
               if
               it
               had
               not
               been
               unseasonably
               rous'd
               and
               assisted
               by
               some
               Ingredient
               ,
               that
               perhaps
               was
               needlesly
               put
               into
               the
               Medicine
               .
               I
               have
               had
               so
               many
               unwelcome
               Proofs
               of
               this
               in
               my self
               ,
               that
               it
               engages
               me
               to
               be
               the
               more
               careful
               to
               caution
               others
               against
               the
               like
               Inconvenience
               .
            
          
           
             
               §
               III
            
             
               ANother
               benefit
               accrewing
               from
               the
               use
               of
               Simpler
               Medecines
               ,
               is
               ,
               that
               thereby
               the
               Patient
               may
               ,
               without
               burdening
               his
               Stomach
               ,
               or
               nauseating
               the
               Remedy
               ,
               take
               a
               larger
               Dose
               of
               the
               Medicine
               ,
               or
               of
               that
               Ingredient
               of
               it
               wherein
               the
               vertue
               chiefly
               resides
               .
               For
               ,
               whereas
               Physicians
               are
               oblig'd
               to
               stint
               themselves
               in
               the
               Dose
               of
               the
               Medicine
               ,
               for
               fear
               of
               disgusting
               the
               Patient
               ,
               or
               oppressing
               his
               Stomach
               ;
               when
               there
               are
               many
               things
               heap'd
               together
               in
               a
               
               moderate
               Dose
               of
               one
               compounded
               Medicine
               ,
               these
               Ingredients
               that
               are
               either
               superfluous
               ,
               or
               at
               least
               are
               less
               efficacious
               ,
               must
               necessarily
               take
               up
               a
               considerable
               part
               of
               that
               determinate
               Dose
               ,
               and
               consequently
               leave
               much
               the
               less
               of
               the
               more
               appropriated
               or
               useful
               Ingredients
               .
            
             
               To
               say
               ,
               that
               all
               the
               Ingredients
               that
               are
               thrust
               into
               a
               great
               composition
               ,
               are
               proper
               and
               conduce
               unto
               the
               same
               purpose
               ,
               I
               doubt
               is
               not
               always
               true
               .
               And
               however
               is
               not
               a
               sufficient
               Answer
               ,
               since
               it
               does
               not
               avoid
               the
               Inconvenience
               I
               have
               been
               objecting
               .
            
             
               If
               a
               Baker
               ,
               being
               to
               make
               the
               best
               Bread
               he
               can
               ,
               especially
               for
               a
               Person
               of
               a
               weak
               Stomach
               ,
               should
               to
               Wheaten
               Flower
               add
               the
               Meal
               of
               Rye
               ,
               of
               Barley
               ,
               and
               of
               Oats
               ;
               tho'
               all
               these
               Ingredients
               be
               good
               and
               nourishing
               ,
               and
               each
               of
               them
               is
               by
               many
               us'd
               to
               make
               Bread
               ,
               yet
               none
               will
               take
               him
               for
               a
               skilful
               Baker
               ,
               and
               few
               would
               prefer
               this
               compounded
               Bread
               ,
               to
               that
               more
               simple
               one
               
               made
               of
               Wheat
               alone
               .
               And
               so
               to
               make
               good
               Gun-Powder
               a
               skilful
               man
               would
               not
               to
               Salt-Peter
               ,
               Brimstone
               ,
               and
               Charcole
               add
               Wax
               ,
               Rosin
               ,
               and
               Camphire
               ,
               though
               these
               be
               very
               inflammable
               Substances
               as
               well
               as
               Sulphur
               .
               And
               thus
               if
               one
               would
               make
               an
               
                 Aqua
                 Vitae
              
               ,
               whereof
               but
               one
               small
               cup
               were
               to
               be
               given
               for
               the
               quick
               recovery
               of
               fainting
               Persons
               ,
               he
               would
               not
               with
               Spirit
               of
               Wine
               ,
               or
               good
               Brandy
               ,
               mix
               Mead
               or
               Cyder
               ,
               and
               strong
               Bear
               or
               Ale
               ,
               tho'
               each
               of
               these
               be
               it self
               a
               Spirituous
               Liquor
               .
            
             
               Gum
               Arabick
               (
               whereof
               I
               prefer
               that
               which
               is
               transparent
               and
               colourless
               )
               is
               prescrib'd
               in
               several
               compositions
               ,
               as
               a
               Drug
               proper
               to
               mitigate
               the
               sharpness
               of
               Urine
               .
               But
               by
               the
               quantity
               of
               the
               other
               Ingredients
               that
               't
               is
               mix'd
               and
               clog'd
               with
               ,
               no
               more
               than
               a
               small
               proportion
               of
               it
               usually
               comes
               to
               be
               given
               in
               one
               Dose
               .
               But
               when
               I
               have
               had
               the
               Curiosity
               ,
               leaving
               out
               all
               the
               other
               things
               ,
               to
               give
               about
               a
               dram
               ,
               or
               perhaps
               more
               
               of
               it
               at
               one
               time
               ,
               reduc'd
               by
               long
               Pounding
               (
               for
               the
               best
               is
               very
               tough
               )
               to
               fine
               Powder
               ,
               in
               a
               large
               draught
               of
               small
               Ale
               or
               Beer
               ,
               or
               some
               other
               convenient
               Vehicle
               ,
               I
               found
               very
               considerable
               Effects
               of
               it
               .
               And
               I
               remember
               that
               a
               Gentleman
               of
               great
               note
               ,
               coming
               to
               bid
               me
               farewel
               ,
               because
               of
               a
               long
               and
               troublesome
               Journey
               ,
               he
               was
               taking
               to
               Mineral
               Waters
               ,
               which
               he
               intended
               to
               drink
               for
               many
               weeks
               ,
               to
               ease
               him
               of
               a
               very
               painful
               sharpness
               of
               Urine
               ;
               I
               that
               knew
               it
               was
               not
               venereal
               nor
               from
               the
               Stone
               of
               the
               Bladder
               (
               for
               when
               those
               Causes
               of
               the
               Strangury
               ,
               the
               Medicine
               is
               not
               near
               so
               powerful
               )
               I
               desir'd
               him
               ,
               before
               he
               went
               to
               make
               use
               of
               this
               Powder
               ,
               once
               ,
               or
               (
               if
               there
               should
               be
               need
               )
               twice
               a
               day
               .
               Which
               when
               he
               had
               done
               ,
               it
               so
               reliev'd
               ,
               him
               that
               he
               thought
               himself
               quite
               cur'd
               ,
               and
               forbore
               his
               intended
               Journey
               not
               only
               that
               Year
               ,
               but
               the
               next
               .
               For
               the
               Chin-cough
               ,
               as
               they
               call
               it
               in
               Children
               ,
               whose
               odd
               Symptoms
               do
               usually
               fright
               the
               Parents
               and
               Attendants
               ,
               
               and
               oftentimes
               frustrate
               the
               Endeavours
               of
               Physicians
               ,
               skilful
               in
               curing
               other
               Coughs
               ,
               I
               have
               not
               known
               any
               magisterial
               composition
               so
               effectual
               ,
               as
               the
               simple
               Juice
               of
               Pulegium
               (
               by
               many
               call'd
               Penny-royal
               )
               sweetn'd
               a
               little
               with
               SugarCandy
               ,
               and
               given
               long
               enough
               from
               time
               to
               time
               ,
               in
               the
               quantity
               of
               a
               Childs
               Spoonful
               .
               (
               This
               Plant
               may
               be
               also
               made
               to
               afford
               a
               Syrup
               ,
               that
               will
               keep
               ,
               and
               is
               useful
               in
               Coughs
               ,
               but
               which
               I
               doubt
               ,
               is
               not
               so
               efficacious
               as
               the
               Simple
               Juice
               .
               )
               There
               are
               many
               and
               obvious
               experiments
               of
               the
               great
               efficay
               of
               so
               simple
               a
               Remedy
               as
               Asses
               Milk
               ;
               (
               which
               yet
               in
               some
               cases
               ,
               I
               think
               inferiour
               to
               Goats
               Milk
               ,
               )
               if
               it
               be
               given
               in
               a
               sufficient
               quantity
               ,
               and
               for
               a
               competent
               time
               ,
               there
               are
               also
               many
               Instances
               of
               dangerous
               and
               stubborn
               Diseases
               ,
               that
               have
               been
               cur'd
               even
               by
               Common
               Cows
               Milk
               ,
               when
               it
               has
               been
               very
               plentifully
               taken
               ,
               and
               for
               a
               long
               continuance
               of
               time
               ,
               and
               perhaps
               it
               is
               no
               less
               remarkable
               ,
               that
               
               in
               a
               far
               less
               time
               now
               and
               then
               ,
               not
               extending
               to
               very
               many
               daies
               ,
               Fluxes
               ,
               as
               Dyarrhaeas
               ,
               and
               tho
               more
               seldom
               even
               Dysenterical
               ones
               ,
               are
               happily
               and
               easily
               cur'd
               ,
               as
               I
               have
               sometimes
               known
               by
               the
               bare
               use
               of
               so
               slight
               a
               Remedy
               as
               Milk
               ,
               wherein
               ,
               whilst
               it
               is
               gently
               boyling
               ,
               an
               equal
               quantity
               of
               fair
               Water
               is
               little
               by
               little
               put
               ,
               till
               at
               last
               there
               remains
               but
               as
               much
               Liquor
               as
               the
               Milk
               alone
               amounted
               to
               at
               first
               .
               This
               simple
               Alimentous
               Medicine
               being
               liberally
               taken
               (
               for
               it
               should
               be
               us'd
               instead
               of
               all
               other
               Drinks
               whilst
               the
               Disease
               continues
               )
               has
               been
               very
               frequently
               found
               to
               cure
               Fluxes
               ,
               not
               all
               of
               one
               sort
               ,
               in
               Ireland
               it self
               ,
               where
               that
               kind
               of
               Disease
               is
               Endemical
               .
               And
               ,
               tho
               I
               have
               formerly
               in
               another
               Paper
               recommended
               the
               use
               of
               
                 Paronychia
                 foliis
                 rutaceis
              
               ,
               against
               that
               sad
               and
               stubborn
               Disease
               the
               
                 Kings-Evil
                 ,
                 yet
              
               I
               presume
               you
               will
               allow
               me
               ,
               by
               the
               mention
               of
               a
               Tryal
               that
               was
               since
               made
               with
               it
               ,
               to
               give
               a
               notable
               Confirmation
               
               of
               the
               Utility
               of
               giving
               an
               Alterative
               Simple
               ,
               if
               need
               require
               ,
               in
               considerable
               quantity
               .
               A
               Physician
               that
               I
               knew
               ,
               was
               sent
               for
               to
               a
               Scrophulous
               Patient
               ,
               in
               whose
               Throat
               there
               was
               a
               Tumour
               ,
               so
               big
               and
               so
               unluckily
               seated
               ,
               that
               much
               compressing
               the
               Asophagus
               it
               rendr'd
               Deglutition
               exceeding
               difficult
               :
               So
               that
               being
               likewise
               so
               hard
               and
               stubborn
               ,
               that
               tho
               the
               Physician
               was
               also
               a
               famous
               Chyrurgion
               ,
               he
               could
               neither
               discuss
               it
               ,
               or
               bring
               it
               to
               Suppuration
               ;
               The
               Patient
               ,
               tho
               rich
               ,
               was
               in
               imminent
               danger
               of
               being
               starv'd
               .
               In
               this
               Strait
               the
               Physician
               remembring
               the
               Character
               I
               had
               given
               of
               Paronychia
               ,
               or
               Whitlom
               Grass
               ,
               sent
               about
               the
               Country
               to
               to
               get
               all
               that
               could
               be
               procur'd
               :
               And
               at
               first
               gave
               a
               little
               of
               it
               in
               form
               of
               Infusion
               ,
               in
               such
               liquid
               Aliments
               as
               the
               Patient
               was
               able
               ,
               with
               much
               ado
               ,
               little
               by
               little
               to
               get
               down
               .
               And
               having
               by
               this
               means
               ,
               after
               some
               time
               ,
               made
               the
               Deglutition
               less
               difficult
               ,
               he
               gave
               the
               Remedy
               
               more
               and
               more
               plentifully
               ,
               to
               imbue
               the
               whole
               mass
               of
               Blood
               and
               Juices
               of
               the
               Body
               with
               the
               Vertue
               of
               the
               Herb
               ,
               whereby
               the
               Tumour
               was
               at
               length
               resolv'd
               ,
               and
               the
               Patient
               secur'd
               ,
               so
               much
               to
               the
               Physicians
               Reputation
               as
               well
               as
               Profit
               ,
               that
               ,
               as
               he
               said
               ,
               he
               thought
               Gratitude
               oblig'd
               him
               to
               give
               me
               a
               Circumstantial
               Account
               of
               his
               Success
               ;
               as
               he
               very
               civilly
               did
               in
               a
               long
               Letter
               whereof
               I
               have
               given
               you
               the
               Substance
               .
            
             
               And
               tho
               I
               might
               here
               entertain
               you
               with
               the
               Vertues
               of
               some
               other
               Simple
               Remedies
               ,
               plentifully
               given
               ,
               yet
               for
               brevity
               sake
               I
               shall
               rather
               observe
               in
               general
               ,
               That
               I
               doubt
               not
               but
               several
               Simple
               Medicines
               (
               I
               speak
               of
               alterative
               not
               evacuating
               ones
               ,
               would
               be
               found
               far
               more
               effectual
               than
               they
               are
               commonly
               thought
               ,
               if
               they
               were
               given
               in
               a
               much
               larger
               Dose
               ,
               and
               continued
               for
               a
               competent
               time
               .
               And
               probably
               so
               many
               Physicians
               (
               especially
               of
               the
               Old
               School
               ,
               )
               would
               not
               be
               so
               
               forward
               to
               reject
               either
               Specifick
               or
               simple
               Remedies
               ,
               as
               having
               found
               some
               of
               them
               not
               to
               answer
               Expectation
               ;
               if
               they
               would
               allow
               them
               as
               fair
               a
               Tryal
               ,
               as
               they
               give
               to
               their
               own
               Prescriptions
               ,
               such
               as
               the
               Chalybeats
               of
               the
               Shops
               ,
               the
               Spaw
               ,
               or
               Tunbridge
               Waters
               ,
               the
               Decoctions
               of
               Guajacum
               ,
               &c.
               which
               they
               often
               give
               with
               divers
               intermediate
               helps
               for
               a
               Month
               or
               six
               Weeks
               ,
               and
               sometimes
               for
               two
               Months
               together
               ,
               without
               expecting
               that
               in
               a
               few
               weeks
               ,
               much
               less
               in
               a
               very
               few
               days
               ,
               they
               should
               perform
               the
               cure
               .
            
          
           
             
               §
               IV.
               
            
             
               THE
               Fourth
               thing
               that
               may
               recommend
               the
               use
               of
               Simple
               Medicines
               ,
               is
               ,
               That
               
                 caeteris
                 paribus
              
               they
               are
               more
               easy
               to
               be
               procur'd
               then
               Compounded
               ones
               .
               This
               Assertion
               needs
               little
               proof
               .
               And
               where
               several
               Simples
               are
               requir'd
               ,
               
               one
               or
               more
               of
               them
               may
               oftentimes
               be
               difficult
               to
               be
               got
               ;
               and
               all
               of
               them
               will
               still
               be
               troublesome
               to
               be
               fetcht
               ,
               and
               to
               be
               made
               up
               into
               a
               Composition
               .
               How
               useful
               the
               knowledge
               of
               Parable
               Remedys
               may
               be
               ,
               I
               have
               indeavour'd
               to
               show
               in
               a
               distinct
               Paper
               ;
               and
               therefore
               shall
               not
               discourse
               of
               it
               here
               ,
               but
               only
               add
               this
               one
               Observation
               ,
               that
               some
               Medicines
               are
               so
               parable
               ,
               that
               without
               resorting
               for
               them
               to
               Apothecarys
               shops
               (
               which
               are
               not
               every
               where
               at
               hand
               ,
               nor
               always
               furnished
               with
               them
               )
               we
               may
               find
               them
               in
               those
               of
               other
               Trades-men
               .
               Thus
               among
               Masons
               and
               Bricklayers
               we
               most
               commonly
               meet
               with
               Quicklime
               ;
               whose
               bare
               Infusion
               in
               common
               Water
               [
               about
               a
               pound
               of
               the
               former
               ,
               as
               't
               is
               more
               or
               less
               strong
               ,
               to
               about
               three
               or
               four
               Quarts
               of
               the
               latter
               ,
               ]
               is
               of
               it self
               a
               good
               Medicine
               in
               divers
               Cases
               ,
               and
               as
               Experience
               has
               perswaded
               me
               ,
               may
               be
               made
               the
               Basis
               of
               several
               good
               Remedys
               ,
               both
               Inward
               and
               Outward
               .
               Among
               the
               
               latter
               of
               which
               may
               be
               reckon'd
               an
               Oyntment
               ,
               that
               I
               usually
               kept
               by
               me
               for
               Burns
               ,
               and
               made
               only
               by
               beating
               up
               strong
               Lime-Water
               with
               as
               much
               good
               Lin-seed
               Oyl
               ,
               as
               could
               be
               made
               throughly
               to
               incorporate
               with
               it
               into
               a
               very
               white
               Unguent
               .
            
             
               And
               I
               shall
               add
               concerning
               Linseed
               Oyl
               ,
               (
               since
               I
               have
               mention'd
               it
               )
               which
               is
               to
               be
               had
               in
               the
               shops
               of
               Varnishers
               and
               Painters
               ;
               that
               of
               it self
               ,
               being
               exhibited
               in
               a
               large
               Dose
               ,
               as
               of
               several
               Ounces
               at
               a
               time
               ,
               I
               have
               known
               it
               answer
               the
               Commendations
               given
               it
               by
               eminent
               Physicians
               ,
               for
               breaking
               of
               Pleuritical
               Empyemas
               Simple
               Oyl
               of
               Turpentine
               also
               ,
               that
               may
               be
               usually
               had
               in
               the
               shops
               of
               the
               same
               Trades-men
               ,
               is
               in
               reality
               a
               noble
               Remedy
               in
               divers
               Affections
               ,
               not
               only
               Inward
               ,
               in
               which
               Chymists
               commend
               it
               ,
               but
               Outward
               too
               .
               And
               I
               have
               had
               great
               thanks
               ,
               both
               from
               Physicians
               and
               Chyrugeons
               ,
               for
               recommending
               the
               use
               of
               it
               to
               them
               in
               Wounds
               ,
               and
               particularly
               ,
               where
               
               one
               would
               expect
               little
               from
               it
               in
               the
               stanching
               of
               Blood
               ,
               if
               it
               be
               seasonably
               apply'd
               very
               hot
               to
               the
               wounded
               Parts
               ,
               where
               it
               also
               much
               promotes
               a
               good
               Digestion
               .
               And
               I
               am
               confirm'd
               in
               the
               good
               Opinion
               I
               have
               long
               had
               of
               this
               Oyl
               ,
               by
               the
               Information
               that
               's
               given
               me
               ,
               That
               very
               experienced
               Chyrurgeon
               has
               lately
               been
               so
               charitable
               ,
               as
               to
               publish
               a
               little
               Book
               ,
               considerable
               for
               the
               useful
               Observations
               it
               contains
               ,
               of
               notable
               Cures
               done
               by
               him
               in
               Chyrurgical
               Cases
               ,
               chiefly
               with
               Oyl
               of
               Turpentine
               .
               And
               I
               shall
               add
               ,
               that
               a
               Chyrurgeon
               to
               a
               great
               Monarch
               ,
               and
               one
               of
               the
               skilfullest
               men
               I
               ever
               met
               with
               of
               his
               Profession
               ,
               confess'd
               to
               me
               ,
               that
               in
               an
               admir'd
               Cure
               that
               he
               had
               then
               lately
               done
               of
               a
               desperate
               Gangrene
               ,
               in
               an
               eminent
               person
               ,
               very
               aged
               and
               almost
               bed-rid
               ,
               the
               Medicine
               he
               ascrib'd
               most
               to
               ,
               was
               the
               Oyl
               we
               were
               speaking
               of
               .
               And
               ,
               because
               both
               he
               and
               others
               make
               much
               and
               good
               use
               of
               Spirit
               of
               Wine
               in
               Gangrens
               ,
               which
               yet
               is
               
               thought
               to
               be
               unmingleable
               with
               Oyl
               of
               Turpentine
               ,
               because
               if
               it
               be
               shaken
               with
               it
               ,
               it
               will
               quickly
               separate
               again
               from
               it
               ;
               I
               thought
               it
               might
               do
               Practitioners
               some
               service
               ,
               to
               make
               for
               them
               a
               Mixture
               of
               Oyl
               of
               Turpentine
               and
               Spirit
               of
               Wine
               ,
               that
               might
               probably
               be
               more
               penetrant
               than
               the
               former
               ,
               and
               less
               fugitive
               than
               the
               latter
               ,
               which
               of
               it self
               does
               not
               stay
               long
               enough
               upon
               the
               Parts
               't
               is
               apply'd
               to
               .
               Which
               Mixture
               I
               easily
               made
               ,
               by
               digesting
               for
               a
               while
               ,
               and
               strongly
               shaking
               from
               time
               to
               time
               ,
               about
               equal
               parts
               by
               guess
               of
               good
               Oyl
               of
               Turpentine
               and
               throughly
               dephlegm'd
               Spirit
               of
               Wine
               ,
               till
               this
               Liquor
               ,
               by
               imbibing
               or
               dissolving
               great
               store
               of
               the
               Oleaginous
               Parts
               ,
               have
               attain'd
               a
               Yellow
               Colour
               ,
               for
               which
               reason
               I
               call
               it
               the
               Tincture
               of
               Oyl
               of
               Turpentine
               .
            
             
               And
               ,
               since
               my
               subject
               has
               led
               me
               into
               the
               shops
               of
               Colour-sellers
               ,
               I
               will
               before
               I
               leave
               them
               ,
               take
               notice
               of
               one
               Simple
               that
               is
               wont
               to
               be
               found
               there
               ,
               which
               if
               it
               were
               
               not
               very
               offensive
               to
               the
               Tast
               ,
               and
               somewhat
               disagreeable
               to
               the
               stomach
               ,
               would
               be
               perhaps
               preferable
               for
               its
               Antinephritick
               Vertue
               ,
               to
               the
               most
               pompous
               Compositions
               of
               the
               shops
               ,
               and
               some
               of
               the
               celebrated
               Arcana
               of
               the
               (
               vulgar
               )
               Chymists
               .
               I
               procur'd
               it
               ,
               not
               without
               some
               difficulty
               ,
               from
               a
               Spagyrist
               ,
               very
               well
               vers'd
               in
               the
               School
               of
               Paracelsus
               and
               Helmont
               ;
               who
               ,
               tho
               a
               sparing
               Commender
               of
               Remedyes
               ,
               extoll'd
               this
               as
               the
               best
               he
               had
               ever
               met
               with
               ,
               to
               cure
               the
               Stone
               where
               it
               was
               not
               too
               big
               to
               pass
               ,
               and
               to
               prevent
               the
               increase
               of
               it
               where
               it
               was
               .
               I
               have
               known
               it
               us'd
               in
               Clysters
               ,
               with
               very
               good
               success
               in
               a
               Fit
               of
               that
               Disease
               .
               But
               Inwardly
               I
               had
               no
               occasion
               to
               try
               it
               but
               upon
               my self
               .
               And
               judging
               it
               innocent
               enough
               ,
               (
               as
               indeed
               I
               found
               it
               rather
               Anodyne
               than
               Driving
               ,
               I
               took
               it
               now
               and
               then
               ,
               mix'd
               with
               Oyl
               of
               sweet
               Almonds
               chiefly
               to
               allay
               the
               Tast
               ,
               for
               otherwise
               I
               had
               long
               found
               that
               alone
               ,
               insufficient
               )
               as
               a
               Preservative
               from
               Grave
               .
               And
               ,
               
               thanks
               be
               to
               God
               ,
               I
               divers
               times
               thought
               it
               more
               manifestly
               effectual
               to
               that
               purpose
               ,
               by
               lessening
               either
               the
               bulk
               of
               the
               Grains
               ,
               or
               the
               quantity
               of
               the
               Sand
               ,
               or
               both
               ,
               than
               any
               of
               the
               Remedyes
               I
               had
               taken
               for
               prevention
               in
               several
               years
               before
               .
               And
               yet
               I
               scarce
               took
               a
               quarter
               of
               the
               Dose
               ,
               prescrib'd
               by
               the
               Spagyrist
               that
               communicated
               the
               Medicine
               to
               me
               ;
               which
               in
               short
               is
               (
               for
               I
               presume
               you
               would
               gladly
               know
               it
               )
               to
               take
               from
               time
               to
               time
               ,
               by
               it self
               or
               in
               some
               convenient
               Vehicle
               two
               or
               three
               ounces
               of
               the
               express'd
               Oyl
               of
               Walnuts
               ,
               which
               ,
               if
               the
               great
               staleness
               of
               it
               he
               requires
               be
               necessary
               ,
               (
               which
               I
               mean
               to
               examine
               by
               Tryals
               )
               is
               scarce
               to
               be
               had
               but
               at
               the
               shops
               of
               Artificers
               ,
               because
               he
               would
               have
               it
               at
               least
               a
               year
               old
               ,
               and
               judg'd
               it
               the
               elder
               the
               better
               .
            
             
               Before
               I
               quite
               leave
               the
               Shops
               of
               Trades-Men
               ,
               I
               shall
               take
               notice
               of
               one
               Medicine
               more
               ,
               that
               seems
               to
               have
               been
               first
               lodg'd
               there
               ,
               and
               from
               thence
               translated
               into
               the
               Shops
               of
               
               Apothecaries
               .
               The
               Medicine
               I
               mean
               is
               Castile
               or
               else
               Venetian
               Soap
               ,
               (
               for
               either
               is
               often
               imploy'd
               in
               stead
               of
               the
               other
               )
               which
               being
               a
               Body
               abounding
               with
               Alcalisite
               Salts
               and
               Oleaginous
               Parts
               well
               combin'd
               ,
               invited
               me
               to
               make
               some
               Experiments
               with
               it
               ,
               as
               a
               Substance
               that
               may
               be
               applicable
               to
               good
               uses
               ,
               not
               only
               Mechanical
               but
               Medical
               .
               Of
               some
               of
               tho
               former
               sort
               I
               elsewhere
               make
               mention
               .
               And
               as
               to
               its
               Medicinal
               vertues
               ,
               I
               take
               notice
               in
               another
               Paper
               of
               its
               Efficacy
               against
               the
               Jaundise
               ;
               for
               which
               I
               have
               since
               been
               inform'd
               ,
               that
               ,
               as
               nauseous
               a
               Medicine
               as
               it
               is
               ,
               't
               is
               in
               great
               request
               among
               some
               Skilful
               Men
               in
               Holland
               .
               And
               some
               fresh
               ,
               but
               not
               sufficient
               ,
               experience
               has
               recommended
               it
               to
               me
               against
               the
               Stone
               .
               But
               that
               vertue
               of
               it
               which
               I
               as
               yet
               most
               prize
               it
               for
               ,
               and
               now
               intend
               to
               communicate
               to
               you
               ,
               you
               will
               best
               gather
               from
               the
               following
               Story
               .
               Having
               had
               some
               dealings
               with
               a
               considerable
               Merchant
               (
               of
               Cork
               ,
               in
               Ireland
               )
               he
               sadly
               complain'd
               
               to
               me
               ,
               that
               he
               was
               afflicted
               with
               a
               necessity
               of
               making
               Bloody
               Water
               to
               that
               degree
               ,
               that
               he
               fear'd
               he
               must
               soon
               quit
               his
               Profession
               ,
               being
               already
               unable
               to
               ride
               about
               his
               business
               ,
               and
               scarce
               able
               to
               walk
               a
               foot
               the
               length
               of
               a
               Street
               ,
               without
               stooping
               to
               make
               red
               Water
               .
               Hereupon
               I
               told
               him
               I
               had
               a
               Medicine
               ,
               that
               ,
               if
               he
               could
               digest
               the
               unpleasantness
               of
               it
               ,
               would
               ,
               I
               thought
               ,
               by
               the
               blessing
               of
               God
               ,
               do
               good
               even
               in
               his
               case
               .
               And
               it
               was
               only
               to
               scrape
               with
               a
               Knife
               as
               much
               Castile
               Soap
               into
               a
               Spoon
               ,
               as
               it
               would
               conveniently
               hold
               without
               being
               press'd
               ,
               
                 i.
                 e.
              
               neat
               a
               dram
               ,
               and
               having
               fill'd
               the
               vacant
               part
               with
               small
               Ale
               ,
               or
               some
               other
               ,
               convenient
               Drink
               ,
               to
               facilicate
               the
               swallowing
               so
               nauseous
               a
               Remedy
               ,
               wash
               it
               down
               with
               a
               somewhat
               large
               Draught
               of
               the
               same
               Liquor
               ,
               or
               other
               fit
               Vehicle
               ,
               repeating
               the
               Dose
               twice
               or
               thrice
               a
               day
               ,
               if
               need
               requir'd
               .
               The
               manifest
               relief
               he
               found
               by
               this
               seemingly
               despicable
               Medicine
               ,
               within
               (
               if
               I
               misremember
               not
               )
               two
               or
               
               three
               days
               ,
               invited
               him
               to
               continue
               the
               use
               of
               it
               a
               while
               longer
               ,
               and
               afterwards
               to
               return
               me
               solemn
               thanks
               for
               it
               ;
               declaring
               that
               now
               for
               four
               years
               together
               he
               had
               liv'd
               quite
               free
               from
               his
               Distemper
               ,
               without
               scrupling
               to
               ride
               Journeys
               on
               Horse
               Back
               ,
               as
               his
               occasions
               requir'd
               .
               To
               which
               he
               added
               ,
               that
               in
               regard
               I
               had
               not
               confin'd
               him
               to
               secresy
               ,
               he
               presum'd
               I
               intended
               the
               Medicine
               should
               do
               as
               much
               good
               as
               might
               be
               ,
               and
               therefore
               scrupled
               not
               to
               give
               it
               to
               several
               others
               ,
               who
               were
               likewise
               happily
               cur'd
               by
               the
               use
               of
               the
               same
               Remedy
               .
               Which
               Account
               was
               therefore
               the
               more
               welcom
               to
               me
               ,
               because
               in
               the
               place
               were
               I
               liv'd
               ,
               I
               had
               not
               opportunity
               to
               make
               further
               Tryals
               of
               its
               Efficacy
               .
               And
               on
               this
               occasion
               I
               shall
               beg
               leave
               to
               advertise
               you
               once
               for
               all
               ,
               in
               reference
               to
               the
               Remedies
               deliver'd
               by
               me
               ,
               either
               in
               this
               Paper
               or
               in
               my
               other
               Writings
               ;
               That
               I
               am
               as
               sensible
               as
               another
               of
               the
               almost
               insuperable
               Difficulty
               ,
               of
               making
               any
               certain
               
               Experiments
               in
               Physick
               ;
               and
               that
               ,
               having
               of
               a
               long
               time
               (
               for
               Reasons
               given
               in
               due
               place
               )
               studiously
               ,
               tho
               not
               unreservedly
               ,
               declin'd
               the
               Occasions
               of
               giving
               (
               and
               consequently
               of
               reiterating
               )
               Medicines
               :
               I
               justly
               desire
               that
               none
               of
               my
               Readers
               ,
               and
               especially
               that
               Dr.
               F.
               would
               too
               much
               rely
               upon
               them
               ,
               till
               they
               have
               been
               more
               competently
               try'd
               ,
               than
               perhaps
               some
               of
               them
               ,
               for
               want
               of
               opportunity
               ,
               have
               been
               ;
               and
               administred
               to
               Patients
               of
               differing
               Complexions
               ,
               Ages
               ,
               and
               other
               Circumstances
               .
            
             
               You
               may
               find
               other
               Instances
               of
               the
               vertue
               of
               Parable
               ,
               and
               some
               of
               them
               unpromising
               Medicines
               ,
               in
               one
               of
               my
               Essay's
               
                 Of
                 the
                 Usefulness
                 of
                 Experimental
                 Philosophy
              
               ;
               to
               which
               I
               the
               less
               scruple
               to
               refer
               you
               ,
               because
               I
               do
               not
               remember
               what
               I
               have
               there
               written
               many
               years
               ago
               ,
               so
               perfectly
               ,
               as
               not
               to
               fear
               that
               I
               might
               by
               enlarging
               this
               Section
               ,
               put
               you
               to
               the
               trouble
               of
               reading
               some
               things
               here
               that
               you
               have
               met
               with
               there
               already
               .
               
               And
               yet
               I
               am
               somewhat
               incouraged
               both
               to
               mention
               to
               you
               that
               Book
               ,
               and
               to
               present
               you
               some
               other
               Receipts
               in
               this
               Paper
               ;
               because
               it
               has
               pleas'd
               God
               so
               far
               to
               bless
               divers
               of
               the
               Medicines
               I
               have
               there
               recommended
               ,
               or
               do
               there
               mention
               ,
               that
               they
               have
               been
               prosperous
               to
               many
               Patients
               ,
               and
               not
               altogether
               unuseful
               to
               some
               noted
               Physicians
               ;
               and
               have
               procur'd
               me
               from
               both
               more
               thanks
               than
               I
               pretended
               to
               ;
               besides
               inviting
               Encouragements
               to
               further
               Communications
               .
            
          
           
             
               §.
               V.
               
            
             
               THE
               last
               thing
               in
               order
               ,
               but
               not
               in
               importance
               ,
               that
               induces
               me
               to
               wish
               ,
               that
               Physicians
               would
               imploy
               Simpler
               Medicines
               as
               much
               as
               conveniently
               may
               be
               ,
               is
               ,
               that
               't
               is
               one
               of
               the
               likeliest
               ways
               ,
               (
               and
               perhaps
               little
               less
               than
               absolutely
               necessary
               )
               to
               promote
               the
               Practical
               
               knowledge
               of
               the
               
                 Materia
                 Medica
              
               .
               For
               ,
               whilst
               in
               one
               Receipt
               ▪
               a
               multitude
               of
               Ingredients
               are
               mingl'd
               ,
               if
               not
               confounded
               ,
               't
               is
               almost
               impossible
               to
               know
               with
               any
               certainty
               ,
               to
               which
               of
               the
               Simples
               the
               good
               or
               bad
               Effect
               of
               the
               Remedy
               is
               to
               be
               attributed
               ,
               or
               whether
               it
               be
               not
               produc'd
               by
               a
               Power
               ,
               resulting
               from
               the
               particular
               Quality's
               of
               all
               of
               them
               ,
               united
               into
               one
               Temperament
               ,
               and
               by
               its
               means
               acting
               conjointly
               ,
               and
               ,
               as
               the
               School
               men
               speak
               
                 per
                 modum
                 unius
              
               .
               So
               that
               by
               this
               way
               of
               heaping
               up
               or
               blending
               Simples
               into
               one
               compounded
               Remedy
               ,
               I
               see
               not
               how
               in
               many
               Ages
               Men
               will
               be
               able
               to
               discover
               the
               true
               qualities
               good
               and
               bad
               ,
               of
               the
               particular
               Bodies
               ,
               that
               are
               compris'd
               under
               the
               name
               of
               the
               
                 Materia
                 Medica
              
               ;
               whereas
               ,
               when
               a
               Physician
               often
               imploys
               a
               Simple
               ,
               and
               observes
               the
               Effect
               of
               it
               ,
               the
               relief
               or
               prejudice
               of
               the
               Patient
               ,
               may
               very
               probably
               ,
               if
               not
               with
               medical
               certainty
               ,
               be
               ascrib'd
               to
               the
               good
               or
               bad
               Qualities
               of
               that
               particular
               Remedy
               .
            
             
             
               And
               this
               difficulty
               of
               discerning
               ,
               what
               Ingredient
               it
               is
               of
               a
               very
               compounded
               Medicine
               ,
               that
               helps
               or
               hurts
               the
               Patient
               ,
               is
               much
               increas'd
               to
               those
               that
               affect
               to
               write
               Bills
               ,
               wherein
               something
               is
               prescrib'd
               ,
               which
               tho
               ,
               because
               it
               goes
               under
               one
               name
               ,
               passes
               but
               for
               one
               Ingredient
               ,
               is
               yet
               a
               very
               compounded
               Body
               ;
               as
               is
               evident
               ,
               in
               those
               many
               pompous
               Receipts
               wherein
               Treacle
               ,
               (
               that
               alone
               consists
               of
               above
               sixty
               several
               Simples
               )
               Methridate
               ,
               and
               divers
               other
               famous
               ancient
               compositions
               ;
               that
               each
               of
               them
               consists
               of
               good
               store
               of
               Ingredients
               .
               I
               had
               once
               thoughts
               of
               drawing
               up
               a
               discourse
               of
               the
               Difficulties
               of
               the
               Medicinal
               Art
               ;
               and
               had
               divers
               materials
               by
               me
               for
               such
               a
               work
               ,
               which
               afterwards
               I
               laid
               aside
               ,
               for
               fear
               it
               should
               be
               misimploy'd
               to
               the
               prejudice
               of
               worthy
               Physicians
               .
               But
               among
               the
               difficulties
               that
               occurr'd
               to
               me
               ,
               I
               shall
               on
               this
               occasion
               mention
               one
               ,
               which
               was
               ;
               That
               't
               is
               a
               harder
               work
               than
               most
               men
               think
               ,
               to
               discover
               
               fully
               the
               nature
               ,
               or
               the
               good
               and
               bad
               quality's
               in
               reference
               to
               Physick
               ,
               of
               this
               or
               that
               single
               Plant
               ,
               or
               other
               Simple
               ,
               that
               has
               a
               place
               in
               the
               
                 Materia
                 Medica
              
               .
               For
               besides
               the
               great
               difference
               that
               there
               may
               be
               in
               Plants
               of
               the
               same
               denomiation
               ,
               according
               to
               the
               Climate
               ,
               Soil
               ,
               the
               goodness
               of
               the
               seeds
               that
               produce
               it
               ,
               the
               culture
               ,
               or
               the
               want
               of
               it
               ,
               the
               time
               of
               the
               year
               ,
               the
               seasonableness
               or
               intemperateness
               of
               the
               weather
               ,
               the
               time
               and
               manner
               of
               gathering
               it
               ,
               how
               it
               has
               been
               kept
               ,
               the
               parts
               of
               it
               that
               are
               ,
               and
               those
               that
               are
               not
               made
               use
               of
               ,
               together
               with
               other
               circumstances
               too
               many
               to
               be
               here
               enumerated
               :
               besides
               all
               these
               ,
               I
               say
               ,
               the
               unheeded
               Textures
               of
               parts
               that
               are
               thought
               of
               an
               uniform
               nature
               ,
               and
               the
               length
               of
               time
               during
               which
               they
               have
               been
               kept
               ,
               without
               being
               suspected
               to
               be
               superannuated
               ,
               and
               indeed
               without
               being
               so
               ,
               may
               so
               much
               vary
               the
               nature
               of
               a
               Plant
               ,
               that
               I
               have
               sometimes
               almost
               in
               a
               trice
               
               shewn
               the
               curious
               a
               notable
               disparity
               in
               the
               parts
               of
               the
               same
               fresh
               Leaf
               of
               a
               common
               Plant
               :
               And
               (
               NB.
               )
               I
               have
               found
               by
               Tryal
               purposely
               made
               ,
               that
               some
               seeds
               of
               common
               use
               in
               Physick
               (
               and
               not
               putrefy'd
               )
               will
               ,
               being
               distill'd
               at
               one
               time
               of
               the
               year
               ,
               afford
               an
               Acid
               Spirit
               or
               Liquor
               ;
               but
               at
               another
               time
               of
               the
               year
               ,
               tho
               destill'd
               the
               same
               way
               without
               any
               addition
               ,
               afford
               not
               an
               Acid
               ,
               but
               a
               kind
               of
               urinous
               Spirit
               ,
               that
               contains
               a
               volatile
               Salt
               ,
               which
               in
               Smell
               ,
               Tast
               ,
               and
               divers
               Operations
               ,
               I
               found
               to
               be
               of
               great
               affinity
               to
               the
               volatile
               Salt
               of
               Urine
               ,
               or
               that
               of
               Hartshorn
               .
               And
               indeed
               so
               many
               things
               may
               be
               pertinently
               and
               usefully
               propos'd
               to
               be
               inquir'd
               into
               ,
               about
               this
               or
               that
               particular
               Plant
               made
               use
               of
               by
               Physicians
               ,
               that
               perhaps
               they
               would
               be
               less
               inclin'd
               to
               compound
               numbers
               of
               them
               in
               one
               Receipt
               ,
               if
               they
               were
               aware
               how
               much
               useful
               employment
               the
               indagation
               of
               the
               Quality's
               of
               so
               much
               as
               a
               few
               single
               Plants
               would
               give
               
               them
               :
               and
               yet
               without
               the
               knowledg
               of
               the
               properties
               of
               the
               separated
               Ingredients
               ,
               a
               Physician
               prescribes
               ,
               it
               will
               be
               scarce
               possible
               for
               him
               to
               know
               ,
               with
               sufficient
               certainty
               ,
               how
               the
               compound
               made
               up
               of
               them
               ,
               will
               be
               qualify'd
               and
               operate
               ,
               which
               reflection
               ,
               I
               the
               less
               scruple
               to
               propose
               ,
               because
               I
               am
               conifirm'd
               in
               it
               by
               Galen
               himself
               ,
               
               who
               very
               Book
               ,
               where
               he
               largely
               treats
               
                 De
                 Medicamentorum
                 Compositione
              
               ,
               hath
               this
               Assertion
               ;
               
                 In
                 universum
                 ,
                 nemo
                 probe
                 uti
                 possit
                 medicamento
                 composito
                 ,
                 qui
                 simplicium
                 vires
                 prius
                 non
                 accurate
                 didicerit
                 .
              
            
             
               I
               presume
               you
               will
               easily
               allow
               ,
               that
               much
               of
               what
               has
               been
               said
               in
               favour
               of
               those
               simple
               Medicines
               we
               owe
               to
               Natures
               (
               or
               rather
               to
               its
               Authors
               )
               Bounty
               ,
               may
               be
               extended
               to
               many
               of
               the
               Remedy's
               that
               are
               afforded
               us
               by
               the
               Chymists
               Art.
               For
               without
               now
               entering
               into
               the
               Question
               ,
               whether
               the
               Spirits
               ,
               Oyls
               ,
               and
               Salts
               ,
               that
               are
               obtain'd
               by
               what
               Spagyrists
               call
               
                 Analyses
                 by
                 the
                 
                 fire
              
               ,
               are
               Principles
               in
               the
               strict
               sense
               of
               the
               word
               ;
               it
               will
               scarce
               be
               doubted
               ,
               but
               that
               the
               Spirit
               ,
               or
               the
               Oyl
               ,
               or
               the
               Salt
               of
               a
               mix'd
               Body
               chymically
               resolv'd
               ,
               is
               so
               slightly
               or
               unequally
               compos'd
               ,
               that
               the
               Ingredient
               whence
               it
               takes
               its
               name
               ,
               is
               far
               more
               predominant
               ,
               than
               it
               was
               when
               combin'd
               with
               others
               ,
               in
               the
               entire
               or
               not
               yet
               Analys'd
               Concrete
               .
               And
               that
               such
               supposed
               Principles
               ,
               OF
               Medicines
               of
               a
               simpler
               Order
               ,
               may
               be
               very
               efficacious
               Remedys
               ,
               may
               be
               justly
               argu'd
               from
               the
               great
               and
               beneficial
               effects
               of
               such
               as
               Oyl
               of
               Vitriol
               ,
               Spirit
               of
               Urine
               (
               NB.
               )
               a
               Medicine
               of
               great
               use
               both
               Inward
               and
               Outward
               ,
               Spirit
               of
               Harts-horn
               ,
               Spirit
               of
               Niter
               ,
               Spirit
               of
               Wine
               ,
               and
               Oyl
               of
               Turpentine
               ;
               of
               which
               last
               nam'd
               Liquor
               I
               shall
               add
               ,
               that
               ,
               besides
               the
               vertues
               already
               ascrib'd
               to
               it
               in
               this
               Paper
               ,
               whilst
               it
               retains
               its
               simplicity
               ,
               it
               may
               in
               many
               Cases
               be
               imploy'd
               as
               a
               Menstruum
               ,
               and
               by
               being
               combin'd
               with
               an
               Ingredient
               or
               two
               ,
               be
               made
               to
               afford
               divers
               
               Medicines
               ,
               which
               tho
               but
               little
               compounded
               ,
               are
               not
               of
               little
               vertue
               .
               For
               I
               have
               found
               it
               readily
               enough
               to
               dissolve
               Camphire
               ,
               Mastick
               ,
               and
               some
               other
               Gums
               ,
               of
               which
               Balsoms
               may
               be
               made
               ,
               and
               others
               may
               be
               obtain'd
               by
               the
               help
               of
               the
               same
               Liquor
               ,
               even
               from
               divers
               Mineral
               and
               Metalline
               Bodies
               .
               I
               
                 will
                 not
                 insist
              
               on
               so
               known
               a
               Medicine
               as
               the
               common
               Terebinthinate
               Balsom
               of
               Sulphur
               ;
               tho
               this
               be
               a
               Remedy
               ,
               with
               as
               much
               as
               't
               is
               peculiarly
               extoll'd
               for
               Diseases
               of
               the
               Lungs
               ,
               (
               wherein
               yet
               its
               heat
               requires
               that
               it
               be
               very
               warily
               given
               to
               Patients
               of
               some
               complexions
               )
               has
               vertues
               that
               are
               not
               confin'd
               to
               the
               Distempers
               of
               those
               parts
               ;
               since
               both
               I
               and
               some
               I
               commended
               it
               to
               ,
               have
               found
               it
               very
               effectual
               (
               outwardly
               apply'd
               )
               in
               troublesome
               Haemorroidal
               Pains
               and
               Tumors
               :
               and
               (
               NB.
               )
               some
               experience
               inclines
               me
               to
               think
               its
               vertues
               may
               not
               be
               much
               greater
               in
               Pulmonick
               than
               in
               Paralytick
               Distempers
               :
               in
               which
               (
               last
               )
               it
               may
               be
               
               us'd
               ,
               not
               only
               Outwardly
               ,
               but
               chiefly
               Inwardly
               ;
               and
               that
               in
               a
               pretty
               large
               Dose
               with
               a
               Cephalick
               ,
               and
               ,
               in
               some
               Cases
               ,
               an
               Antiscorbutick
               Vehicle
               .
               
                 But
                 I
                 shall
                 rather
                 take
                 notice
              
               to
               you
               ,
               that
               perhaps
               it
               will
               be
               found
               worth
               while
               to
               try
               ,
               at
               least
               in
               external
               Affects
               ,
               the
               use
               of
               divers
               Tinctures
               ,
               and
               consequently
               Balsoms
               that
               may
               be
               obtaind
               by
               the
               help
               of
               Oyl
               of
               Turpentine
               from
               divers
               solid
               Mineral
               Body's
               ,
               upon
               which
               I
               have
               found
               by
               tryal
               ,
               that
               this
               Liquor
               may
               be
               ting'd
               (
               tho
               not
               of
               the
               same
               colour
               on
               all
               of
               them
               ,
               )
               among
               which
               I
               shall
               name
               ,
               besides
               Crude
               Zink
               ,
               Crude
               Antimony
               ,
               and
               even
               Crude
               Copper
               (
               in
               filings
               ;
               )
               a
               noble
               Subject
               ,
               Antimonial
               Cinnabar
               ;
               from
               which
               ,
               tho
               I
               found
               I
               could
               (
               but
               not
               hastily
               )
               draw
               a
               fine
               Tincture
               ,
               I
               had
               not
               opportunity
               to
               make
               tryal
               of
               that
               promising
               Medicine
               .
            
          
           
             
             
               §.
               VI.
               
            
             
               ANd
               as
               for
               those
               other
               Medicines
               ,
               that
               are
               not
               made
               by
               bare
               Analysis
               ,
               but
               by
               Synthesis
               or
               composition
               ;
               tho
               I
               think
               an
               experienc'd
               Chymist
               may
               ,
               in
               many
               cases
               ,
               with
               less
               uncertainty
               than
               a
               Galenist
               (
               who
               employs
               Crude
               Ingredients
               of
               a
               more
               compounded
               nature
               )
               foresee
               what
               quality
               the
               produc'd
               mix'd
               Body
               may
               have
               :
               Yet
               I
               could
               wish
               ,
               that
               even
               the
               Spagyrists
               themselves
               were
               more
               sparing
               ,
               than
               many
               of
               them
               are
               ,
               in
               the
               number
               of
               the
               Ingredients
               they
               imploy
               to
               compose
               one
               Medicine
               .
               For
               most
               of
               the
               Arguments
               ,
               upon
               which
               I
               grounded
               my
               Invitation
               to
               the
               use
               of
               simple
               Remedies
               ,
               are
               applicable
               to
               Chymical
               ones
               ,
               as
               well
               as
               others
               :
               And
               on
               this
               occasion
               I
               shall
               represent
               two
               things
               .
            
             
               First
               That
               in
               many
               cases
               ,
               preparations
               skilfully
               diversify'd
               ,
               may
               be
               usefully
               substituted
               to
               composition
               :
               
               Since
               one
               Body
               dexterously
               expos'd
               to
               differing
               Operations
               ,
               may
               acquire
               as
               various
               ,
               or
               as
               considerable
               ,
               Qualities
               ,
               as
               would
               accrew
               to
               it
               by
               the
               addition
               of
               such
               other
               Bodies
               ,
               as
               an
               ordinary
               Chymist
               would
               in
               probability
               associate
               with
               it
               .
               Thus
               ,
               not
               to
               mention
               Quick-silver
               ,
               Antimony
               alone
               ,
               whether
               prepar'd
               without
               addition
               ,
               as
               when
               Flowers
               of
               several
               sorts
               are
               made
               of
               the
               more
               Volatile
               ,
               and
               true
               Antimonial
               Glass
               of
               the
               more
               fixt
               part
               ,
               or
               being
               associated
               but
               with
               one
               or
               two
               Ingredients
               ,
               may
               afford
               a
               skilful
               Spagyrist
               ,
               Medicines
               numerous
               and
               various
               enough
               ,
               almost
               to
               furnish
               a
               Shop
               ;
               or
               at
               least
               to
               answer
               the
               Physicians
               Scope
               ,
               where
               he
               would
               imploy
               an
               Emetick
               ,
               a
               Cathartick
               ,
               a
               Diaphoretick
               ,
               a
               Deobstruent
               ,
               a
               Diuretick
               ,
               a
               Bezoardick
               or
               cordial
               Medicine
               ;
               to
               name
               now
               no
               other
               Qualities
               ,
               that
               may
               be
               found
               in
               some
               Antimonial
               preparations
               ,
               in
               a
               degree
               considerable
               enough
               to
               ennoble
               them
               .
               Which
               .
               Instances
               ,
               and
               others
               of
               the
               like
               nature
               
               I
               presume
               you
               will
               allow
               me
               to
               make
               use
               of
               in
               this
               discourse
               ,
               because
               ,
               though
               I
               do
               commonly
               ,
               yet
               I
               do
               not
               always
               ,
               imploy
               the
               Term
               
                 Simple
                 Medicine
              
               or
               Remedy
               in
               the
               strict
               and
               absolute
               sense
               ,
               but
               in
               a
               comparative
               one
               ,
               that
               excludes
               compositions
               of
               more
               than
               two
               or
               three
               ,
               or
               at
               the
               utmost
               a
               very
               few
               ,
               Ingredients
               .
            
             
               Secondly
               ,
               Without
               bringing
               together
               a
               Chaos
               ,
               or
               so
               much
               as
               a
               considerabe
               number
               ,
               of
               Ingredients
               ,
               one
               or
               two
               ,
               or
               at
               most
               three
               auxilary
               ones
               ,
               if
               judiciously
               chosen
               and
               skilfully
               manag'd
               ,
               may
               oftentimes
               produce
               more
               efficacious
               Remedies
               ,
               than
               the
               admirers
               of
               pompuous
               Processes
               would
               expect
               ,
               or
               perhaps
               be
               able
               to
               make
               those
               Processes
               vye
               with
               .
               The
               violently
               Emetick
               and
               purgative
               vertue
               of
               Glass
               of
               Antimony
               made
               
                 per
                 se
              
               ,
               may
               be
               ,
               as
               I
               elsewhere
               show
               ,
               more
               powerfully
               corrected
               by
               mere
               distill'd
               Vinegar
               ,
               than
               by
               many
               famous
               Stomachick
               and
               Cordial
               Elixirs
               ,
               and
               other
               Elaborate
               Preparations
               .
               And
               sometimes
               a
               seemingly
               
               improper
               addition
               may
               not
               only
               correct
               ,
               but
               give
               new
               and
               unexpected
               vertues
               to
               a
               Drug
               .
               Thus
               ,
               though
               
                 Sublimatum
                 corrosivum
              
               be
               a
               mercurial
               concrete
               ,
               so
               fretting
               ,
               that
               a
               very
               few
               Grains
               of
               it
               may
               be
               able
               to
               kill
               a
               man
               ;
               yet
               by
               adding
               and
               carefully
               uniting
               to
               it
               about
               an
               equal
               weight
               of
               running
               Mercury
               ,
               there
               is
               obtain'd
               ,
               when
               they
               are
               well
               united
               by
               Sublimations
               ,
               a
               Compound
               that
               is
               so
               free
               from
               being
               corrosive
               ,
               that
               Chymists
               call
               it
               
                 Mercurius
                 dulcis
              
               ,
               which
               though
               some
               unwary
               Practitioners
               ,
               as
               well
               Galenists
               as
               Chymists
               ,
               have
               too
               often
               by
               their
               misimployment
               of
               it
               ,
               discredited
               ,
               yet
               experience
               shows
               that
               in
               Skilful
               hands
               it
               may
               be
               usefully
               imployed
               ,
               not
               only
               in
               some
               venereal
               affections
               ,
               but
               in
               divers
               other
               Distempers
               .
               And
               I
               shall
               now
               add
               ,
               that
               being
               carefully
               prepar'd
               ,
               and
               well
               given
               ,
               it
               may
               not
               only
               be
               freed
               from
               corrosiveness
               ,
               but
               much
               allay
               the
               Sharpness
               both
               of
               some
               emptying
               Medicines
               ,
               &
               of
               some
               peccant
               humors
               .
               To
               countenance
               
               the
               latter
               part
               of
               which
               observation
               ,
               I
               shall
               acquaint
               you
               with
               one
               use
               of
               it
               ,
               that
               perhaps
               you
               have
               not
               yet
               made
               .
               I
               remember
               ,
               I
               had
               an
               opportunity
               to
               observe
               the
               Efficacy
               of
               
                 Mercurius
                 dulcis
              
               ,
               in
               a
               stubborn
               disentery
               ,
               that
               had
               baffled
               the
               Remedies
               of
               an
               eminent
               Physician
               .
               But
               though
               a
               reflection
               on
               the
               vertue
               ,
               I
               knew
               this
               Medicine
               to
               have
               ,
               of
               allaying
               Sharp
               humors
               ,
               and
               resisting
               Putrefaction
               ,
               may
               justly
               increase
               my
               favourable
               opinion
               of
               it
               ;
               yet
               not
               thinking
               my
               Experience
               competent
               ,
               I
               imparted
               it
               to
               an
               ancient
               and
               expert
               Chyrurgeon
               ,
               that
               was
               the
               chief
               of
               those
               that
               belong'd
               to
               a
               famous
               and
               judicious
               General
               of
               an
               Army
               ;
               who
               thereupon
               frankly
               confess'd
               to
               me
               ,
               that
               this
               was
               his
               great
               Arcanum
               ,
               wherewith
               he
               had
               cur'd
               many
               scores
               ,
               or
               rather
               hundreds
               of
               Souldiers
               in
               this
               generals
               Army
               .
               Only
               ,
               where
               as
               my
               way
               is
               to
               give
               from
               8
               ,
               or
               10
               ,
               to
               12
               ,
               or
               at
               most
               15
               Grains
               of
               
                 Mercurius
                 dulcis
              
               for
               a
               Dose
               ,
               made
               up
               with
               some
               little
               
                 Rhubarb
                 ,
                 &c.
              
               
               Or
               other
               
               Ingredient
               that
               would
               make
               it
               work
               ,
               once
               ,
               twice
               ,
               or
               thrice
               with
               another
               Patient
               ,
               (
               for
               the
               disentery
               it self
               helps
               to
               carry
               off
               the
               Medicine
               )
               he
               ,
               both
               to
               disguise
               it
               ,
               and
               to
               make
               it
               more
               easily
               takeable
               ,
               made
               it
               up
               with
               Sugar
               and
               Mucilage
               of
               Cum-dragon
               into
               Lozenges
               ,
               whereof
               one
               might
               containfrom
               near
               a
               Scruple
               to
               half
               a
               dram
               of
               the
               
                 Mercurius
                 dulcis
              
               ,
               of
               which
               he
               order'd
               the
               Souldiers
               to
               take
               one
               at
               a
               time
               ,
               without
               hindering
               their
               March
               ;
               only
               bidding
               them
               have
               a
               great
               care
               ,
               that
               nothing
               should
               stick
               between
               their
               Teeth
               ,
               or
               in
               their
               Throats
               .
            
             
               3.
               
               But
               the
               efficacy
               of
               this
               simple
               preparation
               of
               Mercury
               ,
               is
               much
               inferiour
               to
               that
               more
               simple
               ,
               although
               more
               tedious
               ,
               preparation
               of
               Gold
               ,
               which
               was
               made
               the
               same
               way
               in
               two
               differing
               Countries
               ,
               by
               two
               dexterous
               Physicians
               ,
               both
               of
               them
               of
               my
               acquaintance
               .
               For
               though
               I
               had
               long
               been
               prejudic'd
               (
               not
               without
               specious
               grounds
               )
               against
               pretended
               
                 Aurum
                 potabiles
              
               ,
               and
               other
               
               boasted
               preparations
               of
               Gold
               ;
               (
               for
               most
               of
               which
               I
               have
               still
               no
               over-great
               esteem
               )
               yet
               ,
               I
               saw
               such
               extraordinary
               and
               surprizing
               Effects
               of
               the
               Tincture
               of
               Gold
               I
               speak
               of
               ,
               upon
               Persons
               of
               great
               note
               ,
               that
               I
               was
               particularly
               acquainted
               with
               both
               before
               they
               fell
               desperately
               sick
               ,
               and
               after
               their
               strange
               Recovery
               ,
               that
               I
               could
               not
               but
               change
               my
               former
               opinion
               ,
               or
               a
               very
               favourable
               one
               of
               some
               preparations
               of
               Gold
               ;
               and
               I
               should
               have
               thought
               that
               this
               Medicine
               (
               as
               little
               compounded
               as
               it
               is
               ,
               )
               could
               scarce
               he
               paid
               ,
               by
               a
               great
               store
               of
               the
               Noble
               Metal
               that
               afforded
               it
               ,
               if
               it
               could
               have
               been
               made
               in
               great
               quantity
               ,
               or
               without
               a
               great
               deal
               of
               pains
               and
               time
               .
               I
               can
               speak
               thus
               circumstantially
               ,
               because
               by
               the
               kindness
               of
               the
               Artists
               ,
               and
               the
               pains
               I
               had
               spent
               in
               working
               on
               the
               same
               Subject
               they
               make
               their
               Menstruum
               of
               ,
               I
               so
               far
               knew
               ,
               and
               partly
               (
               by
               themselves
               invited
               )
               saw
               ,
               the
               preparation
               of
               it
               ,
               that
               to
               bring
               home
               what
               has
               been
               said
               ,
               to
               the
               present
               occasion
               )
               I
               can
               tell
               
               you
               ,
               that
               there
               is
               no
               Ingredient
               associated
               to
               the
               Gold
               ,
               save
               one
               ,
               that
               comes
               from
               above
               ,
               and
               is
               reputed
               one
               of
               the
               simplest
               Bodys
               in
               nature
               ,
               and
               of
               which
               one
               may
               take
               two
               or
               three
               Ounces
               altogether
               unprepar'd
               ,
               without
               the
               least
               inconvenience
               .
               And
               yet
               the
               Dose
               of
               this
               almost
               insipid
               Medicine
               ,
               that
               was
               given
               to
               an
               old
               Courtier
               ,
               even
               in
               a
               violent
               Apoplexy
               ,
               wherein
               other
               Remedies
               had
               by
               skil'ful
               men
               been
               us'd
               in
               vain
               ,
               was
               but
               six
               or
               eight
               drops
               .
            
             
               In
               another
               very
               ancient
               and
               corpulent
               person
               the
               Dose
               was
               greater
               ,
               because
               the
               Tincture
               was
               more
               unripe
               and
               diluted
               ;
               but
               the
               effect
               was
               as
               sudden
               ,
               tho
               the
               Patient
               was
               not
               bled
               ,
               and
               tho
               there
               was
               not
               in
               either
               of
               these
               two
               cases
               ,
               any
               notably
               sensible
               ,
               evacuation
               made
               .
               [
               Both
               these
               recover'd
               Persons
               are
               yet
               alive
               ]
               the
               same
               Medicine
               a
               while
               after
               ,
               saved
               the
               life
               of
               another
               Gentleman
               I
               know
               ,
               who
               ,
               having
               lain
               above
               two
               and
               twenty
               days
               sick
               of
               an
               ill
               conditioned
               Feaver
               ,
               was
               condemn'd
               
               by
               three
               Physicians
               ,
               whereof
               one
               told
               me
               with
               great
               grief
               ,
               that
               he
               would
               not
               out-live
               the
               next
               morning
               ;
               and
               yet
               upon
               the
               taking
               of
               a
               large
               Dose
               of
               this
               Tincture
               ,
               he
               was
               presently
               reliev'd
               ,
               and
               from
               that
               time
               found
               a
               sensible
               amendment
               towards
               a
               recovery
               ,
               which
               he
               now
               injoys
               ;
               tho
               he
               were
               then
               reputed
               to
               be
               about
               ,
               if
               not
               above
               fourscore
               years
               old
               .
               Some
               other
               odd
               effects
               of
               this
               .
               Remedy
               I
               could
               tell
               you
               of
               :
               But
               it
               has
               already
               much
               swell'd
               this
               Section
               ,
               and
               yet
               I
               thought
               it
               not
               amiss
               to
               relate
               these
               things
               to
               you
               ,
               both
               ,
               because
               they
               are
               very
               pertinent
               to
               the
               scope
               of
               it
               ,
               and
               because
               you
               may
               be
               ,
               as
               I
               long
               was
               ,
               prejudic'd
               against
               Medicines
               made
               of
               so
               fix'd
               ,
               and
               ,
               as
               is
               suppos'd
               ,
               un-alterable
               a
               Metal
               as
               Gold.
               
            
             
               4.
               
               This
               is
               not
               the
               only
               Medicine
               made
               of
               that
               noble
               Body
               ,
               of
               which
               I
               have
               known
               very
               notable
               effects
               .
               But
               ,
               because
               they
               belong
               to
               another
               Paper
               ,
               I
               shall
               not
               particularly
               mention
               them
               in
               this
               ;
               but
               pass
               on
               to
               
               tell
               you
               ,
               
               that
               the
               Preparation
               of
               Silver
               ,
               that
               I
               have
               long
               since
               deliver'd
               in
               another
               Book
               ,
               tho'
               it
               may
               seem
               but
               slight
               ,
               has
               been
               found
               very
               effectual
               ,
               and
               much
               us'd
               ,
               by
               one
               of
               the
               eminentest
               Physicians
               of
               this
               nation
               ,
               to
               whom
               I
               recommended
               it
               :
               and
               who
               acknowledg'd
               to
               me
               ,
               that
               He
               gave
               it
               to
               Patients
               of
               very
               high
               Quality
               ,
               tho'
               disguis'd
               ,
               to
               avoid
               alarming
               those
               that
               are
               fearful
               of
               Chymical
               Medicines
               .
               And
               since
               that
               I
               gave
               it
               to
               a
               great
               Lady
               that
               was
               Hydropical
               ,
               and
               judg'd
               to
               be
               dangerously
               ill
               ,
               with
               notable
               success
               ;
               and
               the
               Cure
               has
               already
               for
               some
               years
               held
               good
               .
               But
               I
               confess
               to
               you
               ,
               that
               I
               look
               upon
               Copper
               ,
               and
               its
               Magistery
               
                 Blew
                 Vitriol
              
               ,
               as
               a
               much
               nobler
               Subject
               to
               make
               Remedy's
               of
               ,
               than
               Silver
               ,
               and
               perhaps
               than
               Gold
               it self
               .
               And
               if
               I
               were
               to
               make
               Physick
               my
               Profession
               ,
               there
               is
               no
               Metal
               which
               I
               should
               so
               willingly
               bestow
               pains
               upon
               as
               Copper
               induc'd
               thereunto
               by
               the
               excellent
               and
               very
               extraordinary
               
               Effects
               ,
               (
               not
               all
               of
               them
               to
               be
               mention'd
               in
               this
               Paper
               ,
               that
               I
               have
               had
               opportunity
               to
               see
               ,
               of
               some
               Remedies
               ,
               which
               tho'
               I
               could
               never
               learn
               how
               to
               make
               ,
               I
               knew
               were
               made
               of
               that
               Metal
               ,
               or
               Vitriol
               abounding
               in
               it
               .
               [
               But
               first
               freed
               from
               all
               cruelticle
               violence
               .
               ]
               And
               for
               appeasing
               of
               Pains
               ,
               produc'd
               even
               by
               inveterate
               Maladies
               ,
               the
               Laudanums
               )
               and
               other
               opiate
               Preparations
               ,
               that
               are
               prescrib'd
               and
               prais'd
               in
               Physicians
               and
               Chymists
               Books
               ,
               and
               much
               us'd
               (
               oftentimes
               with
               good
               success
               )
               in
               their
               practice
               ,
               seem
               to
               me
               ,
               bccause
               of
               the
               Stupor
               ,
               and
               some
               other
               inconvenient
               Symptoms
               ,
               they
               are
               wont
               more
               or
               less
               to
               be
               followed
               by
               ,
               far
               inferiour
               to
               the
               
                 Sulphureous
                 Parts
              
               ,
               as
               a
               Chymist
               would
               call
               them
               ,
               of
               skillfully
               prepar'd
               Venus
               ;
               these
               being
               much
               more
               harmlesly
               and
               friendly
               Anodynous
               .
               And
               I
               remember
               that
               an
               Empyrick
               ,
               to
               whom
               ,
               at
               his
               request
               ,
               I
               taught
               a
               very
               uncertain
               way
               (
               for
               it
               rarely
               hits
               )
               of
               making
               a
               kind
               of
               
                 Sulphur
                 of
                 Vitriol
              
               alone
               ,
               in
               the
               form
               
               of
               a
               Brick
               colour'd
               Powder
               ;
               came
               purposely
               to
               give
               me
               solemn
               Thanks
               for
               the
               Reputation
               he
               had
               gain'd
               by
               that
               Medicine
               ,
               of
               which
               the
               first
               time
               he
               had
               the
               good
               luck
               to
               make
               it
               ,
               he
               gave
               ,
               as
               he
               was
               instructed
               ,
               four
               or
               five
               grains
               of
               it
               ,
               to
               a
               Woman
               that
               could
               not
               sleep
               ,
               but
               had
               been
               for
               divers
               months
               raving
               mad
               ,
               [
               Maniaca
               .
               ]
               which
               single
               dose
               not
               only
               gave
               her
               a
               good
               Nights
               rest
               ,
               but
               brought
               .
               her
               to
               talk
               sense
               when
               she
               wak'd
               in
               the
               Morning
               .
               I
               knew
               also
               a
               Chymist
               ,
               that
               was
               much
               courted
               even
               by
               learned
               Doctors
               ,
               for
               an
               internal
               Anodyne
               he
               us'd
               ,
               and
               could
               sell
               at
               almost
               what
               rate
               he
               pleas'd
               ,
               to
               take
               off
               inveterate
               Pains
               in
               the
               Heads
               and
               Shins
               of
               venereal
               Patients
               ;
               and
               the
               same
               Person
               cur'd
               venereal
               Ulcers
               in
               a
               very
               short
               time
               ,
               only
               by
               strowing
               on
               them
               an
               Indolent
               Powder
               .
               And
               tho
               he
               was
               so
               shy
               ,
               that
               he
               would
               not
               let
               even
               the
               Physicians
               ,
               I
               recommended
               to
               him
               ,
               see
               his
               Medicine
               ,
               yet
               having
               one
               day
               been
               told
               of
               a
               kindness
               I
               had
               done
               
               him
               ,
               unknown
               to
               him
               ;
               he
               took
               it
               so
               well
               ,
               that
               he
               not
               only
               allow'd
               me
               to
               see
               and
               handle
               his
               Medicine
               ,
               but
               when
               I
               guess'd
               by
               the
               ponderousness
               and
               effects
               ;
               of
               it
               ,
               that
               it
               was
               some
               .
               Preparation
               of
               Mercury
               fixt
               with
               
                 Sulphur
                 of
                 Venus
              
               ,
               he
               frankly
               acknowledg'd
               to
               me
               ,
               that
               ,
               tho
               it
               would
               indure
               not
               only
               Ignition
               ,
               but
               a
               strong
               &
               lasting
               fire
               ,
               that
               in
               the
               former
               part
               of
               my
               Conjecture
               (
               
                 that
                 the
                 Body
                 of
                 it
                 was
                 Mercurial
              
               )
               I
               was
               in
               the
               right
               ;
               and
               in
               the
               latter
               part
               I
               shot
               very
               near
               the
               Mark
               ;
               but
               added
               ,
               that
               that
               the
               true
               
                 Sulphureous
                 parts
              
               of
               Venus
               were
               in
               his
               way
               so
               difficult
               to
               be
               obtain'd
               ,
               and
               requir'd
               so
               much
               time
               ,
               that
               he
               could
               seldom
               prevail
               with
               himself
               ,
               (
               who
               indeed
               was
               voluptuous
               enough
               )
               to
               go
               through
               so
               troublesome
               a
               work
               .
               And
               in
               effect
               I
               found
               ,
               upon
               various
               Tryals
               ,
               the
               constituent
               Parts
               of
               that
               Metal
               to
               be
               much
               more
               strictly
               united
               than
               the
               generality
               even
               of
               Chymists
               imagaine
               .
               For
               the
               extraordinary
               effects
               of
               this
               Medicine
               ,
               I
               can
               refer
               you
               to
               
               the
               Testimony
               of
               very
               ingenious
               men
               of
               your
               own
               Profession
               ,
               (
               and
               probably
               acquaintance
               too
               .
               )
               And
               since
               I
               know
               you
               study
               Helmont
               ,
               I
               presume
               you
               will
               the
               more
               readily
               believe
               them
               ,
               if
               I
               put
               you
               in
               mind
               of
               that
               notable
               Passage
               ,
               where
               he
               says
               :
               
                 Nihil
                 ,
                 aeque
                 victoriose
                 in
                 Humidum
                 Radicale
                 ,
                 agit
                 atque
                 primum
                 ens
                 cupri
                 ,
                 vel
                 ad
                 vitam
                 longam
                 Sulphure
                 vitrioli
                 est
                 benignius
                 ;
                 ideoque
                 Sulphur
                 Philosophorum
                 indigitat
                 .
              
               But
               my
               intended
               Brevity
               forbids
               me
               to
               insist
               longer
               on
               this
               Metal
               ,
               or
               to
               take
               notice
               of
               more
               than
               one
               other
               Metal
               .
               And
               because
               that
               of
               Steel
               ,
               Physicians
               as
               well
               as
               Chymists
               make
               great
               variety
               of
               Remedies
               ,
               some
               of
               which
               are
               produc'd
               by
               Preparations
               slight
               enough
               ;
               And
               the
               like
               may
               be
               said
               of
               Mercury
               ,
               witness
               the
               Remedy
               formerly
               commended
               against
               the
               Worms
               ,
               made
               of
               nothing
               but
               crude
               Quick-Silver
               barely
               decocted
               in
               common
               water
               :
               For
               this
               reason
               ,
               I
               say
               ,
               I
               shall
               pitch
               upon
               Lead
               ,
               whose
               calx
               dissolv'd
               in
               Spirit
               of
               Vinegar
               affords
               
               as
               you
               know
               ,
               
                 Saccharum
                 Saturni
              
               ,
               which
               tho
               so
               easy
               and
               simple
               a
               preparation
               ,
               is
               a
               magistery
               that
               has
               more
               vertues
               than
               every
               Physican
               knows
               ,
               or
               perhaps
               so
               much
               as
               suspects
               ;
               especially
               in
               mortifying
               sharp
               humours
               in
               the
               Eyes
               ,
               which
               I
               have
               known
               or
               made
               it
               do
               sometimes
               almost
               in
               a
               trice
               .
               [
               But
               I
               do
               not
               think
               it
               safe
               to
               make
               the
               Plantain
               or
               Rose-water
               't
               is
               to
               be
               dissolv'd
               in
               ,
               considerably
               strong
               of
               it
               .
               ]
               And
               for
               Burns
               ,
               I
               have
               seldom
               seen
               any
               thing
               equal
               to
               it
               ,
               and
               therefore
               have
               often
               us'd
               it
               upon
               my self
               (
               barely
               dissolv'd
               in
               Common
               ,
               or
               else
               Plantain
               Water
               .
               )
               But
               I
               fear
               't
               is
               not
               so
               safe
               as
               effectual
               ,
               in
               some
               inward
               Distempers
               of
               the
               Bowels
               ,
               that
               are
               judg'd
               to
               be
               caus'd
               by
               Acid
               humours
               ;
               unless
               it
               be
               very
               warily
               and
               skilfully
               given
               .
               [
               But
               as
               to
               its
               external
               use
               ,
               I
               presume
               ,
               I
               need
               not
               tell
               so
               skilful
               a
               Doctor
               as
               you
               (
               NB.
               )
               how
               great
               it
               is
               in
               healing
               ,
               and
               in
               the
               mean
               time
               appeasing
               ,
               the
               Pains
               of
               divers
               sorts
               of
               Ulcers
               .
               And
               therefore
               I
               shall
               mention
               but
               one
               
               Particular
               ,
               which
               't
               is
               like
               you
               have
               not
               met
               with
               ;
               namely
               ,
               that
               I
               know
               a
               very
               Ancient
               and
               experienc'd
               Person
               ,
               who
               ,
               besides
               a
               vast
               practice
               otherwise
               ,
               was
               Chyrurgeon
               to
               a
               great
               Hospital
               ;
               who
               professing
               much
               kindness
               ,
               and
               owning
               some
               obligation
               to
               me
               ,
               confess'd
               to
               me
               ,
               that
               amongst
               all
               the
               Medicines
               he
               has
               try'd
               to
               stop
               Bleeding
               ,
               and
               prevent
               Accidents
               in
               Amputations
               ,
               that
               which
               he
               oftenest
               us'd
               ,
               and
               most
               rely'd
               on
               ,
               is
               a
               solution
               of
               
                 Saccharum
                 Saturni
              
               in
               Plantain
               Water
               (
               or
               for
               a
               need
               in
               pure
               common
               Water
               :
               )
               for
               having
               dissolv'd
               ℥
               j.
               of
               the
               former
               in
               about
               a
               Pint
               or
               pound
               of
               the
               latter
               ;
               as
               soon
               as
               ever
               the
               Limb
               or
               other
               part
               is
               taken
               off
               ,
               he
               immediately
               apply's
               Stupes
               drench'd
               in
               this
               Liquor
               ,
               as
               hot
               as
               the
               Patient
               can
               well
               endure
               ;
               and
               having
               bound
               them
               carefully
               on
               ,
               he
               makes
               ,
               no
               hast
               to
               take
               them
               off
               ,
               but
               allows
               the
               Medicine
               time
               enough
               to
               perform
               its
               operation
               :
               To
               countenance
               this
               I
               would
               tell
               you
               an
               odd
               experiment
               of
               mine
               ,
               of
               the
               efficacy
               
               of
               a
               Saturnine
               Liquor
               to
               resist
               Putr
               faction
               ,
               in
               the
               Bodys
               of
               Animals
               ,
               but
               that
               the
               relation
               would
               take
               up
               too
               much
               time
               .
               ]
            
             
               5.
               
               Perhaps
               I
               need
               not
               tell
               you
               ,
               that
               I
               could
               here
               mention
               divers
               other
               Experiments
               ,
               as
               well
               upon
               Saturn
               ,
               as
               the
               other
               Metals
               I
               have
               nam'd
               above
               ;
               but
               that
               my
               Scope
               confines
               me
               to
               such
               Preparations
               ,
               as
               wherein
               the
               Metaline
               Subject
               is
               compounded
               but
               with
               very
               few
               others
               ;
               and
               also
               that
               of
               those
               that
               are
               more
               remote
               from
               simplicity
               ,
               you
               may
               meet
               with
               several
               in
               some
               of
               my
               other
               Papers
               ,
               which
               I
               am
               not
               in
               this
               to
               defraud
               .
            
             
               What
               has
               been
               above
               noted
               about
               Metals
               ,
               may
               be
               extended
               to
               Minerals
               :
               namely
               ,
               that
               when
               there
               is
               need
               to
               compound
               them
               ,
               it
               may
               of
               tentimes
               be
               sufficient
               to
               associate
               them
               with
               one
               or
               two
               ,
               or
               at
               most
               a
               very
               few
               
                 Auxiliary
                 Ingredients
              
               ,
               if
               I
               may
               so-call
               them
               ;
               this
               is
               apparent
               in
               several
               useful
               Preparations
               of
               Antimony
               ,
               that
               are
               vulgarly
               enough
               known
               .
               
               To
               which
               divers
               may
               be
               added
               that
               are
               made
               of
               common
               Sulphure
               ,
               by
               slight
               additions
               .
               Of
               which
               sort
               ,
               because
               I
               elsewhere
               deliver
               several
               ,
               I
               shall
               now
               mention
               but
               one
               ,
               which
               though
               I
               have
               many
               years
               ago
               describ'd
               in
               the
               History
               of
               colours
               ,
               I
               shall
               not
               scruple
               to
               take
               notice
               of
               here
               ,
               because
               I
               there
               consider
               not
               its
               Medicinal
               vertues
               ,
               which
               yet
               are
               very
               great
               ,
               especially
               in
               Asthmas
               and
               Coughs
               ,
               in
               which
               I
               do
               not
               remember
               that
               I
               ever
               gave
               it
               without
               benefit
               to
               the
               Patient
               ;
               nor
               was
               it
               less
               successful
               in
               the
               hands
               of
               Physicians
               ,
               that
               were
               willing
               to
               try
               it
               for
               me
               ,
               especially
               in
               those
               of
               a
               Person
               ,
               who
               though
               well
               furnish'd
               with
               choice
               Remedies
               of
               his
               own
               ,
               often
               came
               to
               me
               for
               a
               supply
               of
               this
               Spirituous
               and
               penetrating
               Tincture
               ,
               with
               which
               he
               assur'd
               me
               he
               did
               notable
               things
               in
               Asthmatical
               cases
               ;
               and
               particularly
               in
               one
               that
               was
               very
               obstinate
               ,
               and
               had
               lasted
               many
               years
               .
               But
               not
               having
               had
               quite
               so
               many
               opportunities
               as
               I
               wished
               of
               giving
               it
               my self
               ,
               I
               shall
               
               be
               glad
               ,
               that
               further
               Tryal
               may
               be
               made
               of
               it
               by
               so
               skilful
               an
               Administrer
               as
               you
               .
               And
               therefore
               lest
               you
               should
               not
               have
               the
               Book
               lately
               refer'd
               to
               at
               hand
               ,
               I
               shall
               here
               repeat
               ,
               that
               our
               Medicine
               is
               made
               of
               Flowers
               of
               Sulphur
               ,
               exactly
               mix't
               with
               an
               equal
               weight
               of
               finely
               powder'd
               Sal-Armoniac
               ,
               and
               somewhat
               more
               than
               an
               equal
               weight
               of
               good
               Quick-lime
               ,
               separately
               reduc'd
               to
               a
               Suttle
               Powder
               .
               For
               these
               three
               Ingredients
               being
               diligently
               and
               nimbly
               mix'd
               ,
               and
               put
               into
               a
               Retort
               ,
               to
               be
               plac'd
               in
               a
               sand
               Furnace
               ,
               and
               fitted
               with
               a
               large
               receiver
               very
               well
               luted
               to
               it
               .
               This
               Mixture
               ,
               I
               say
               ,
               being
               duly
               distill'd
               in
               such
               vessels
               ,
               will
               afford
               a
               Blood
               red
               and
               smoaking
               spirit
               ,
               exceeding
               Sulphureous
               both
               in
               smell
               and
               oven
               Mechanical
               Operations
               .
               And
               in
               this
               Distillation
               the
               Sulphureous
               Parts
               sometimes
               came
               over
               accompany'd
               with
               such
               store
               of
               saline
               ones
               ,
               that
               a
               good
               part
               of
               what
               past
               into
               the
               Receiver
               shot
               into
               the
               form
               of
               a
               
                 Volatile
                 Sulphureous
                 Salt.
              
               And
               I
               
               remember
               that
               having
               for
               curiosity's
               sake
               added
               to
               the
               Fluid
               Tincture
               a
               due
               proportion
               of
               an
               Ardent
               Spirit
               (
               such
               as
               that
               of
               Wine
               )
               exactly
               dephlegm'd
               ,
               I
               had
               a
               Mixture
               (
               whether
               in
               the
               form
               of
               a
               Coagulum
               or
               not
               )
               which
               afforded
               me
               some
               odd
               Phaenomena
               not
               here
               to
               be
               mention'd
               ,
               and
               which
               we
               subled
               with
               a
               gentle
               fire
               to
               unite
               them
               into
               a
               composition
               that
               may
               for
               distinction
               sake
               be
               call'd
               
                 Sa
                 trium
                 regnorum
              
               ,
               because
               it
               contains
               Urinous
               Particles
               ,
               Vinous
               ones
               ,
               (
               and
               perhaps
               some
               of
               Soot
               )
               and
               Sulphureous
               ones
               :
               whereof
               the
               First
               belongs
               to
               the
               Animal
               ,
               the
               Second
               to
               the
               Vegetable
               ,
               and
               the
               last
               to
               the
               Mineral
               Kingdom
               ,
               as
               Chymists
               are
               wont
               to
               speak
               .
               But
               what
               vertues
               this
               Salt
               (
               that
               would
               presently
               gild
               Silver
               ,
               )
               and
               the
               Spirit
               that
               may
               be
               made
               to
               accompany
               it
               ,
               may
               have
               in
               Physick
               ,
               I
               had
               not
               occasion
               to
               try
               .
               But
               yet
               I
               have
               mention'd
               it
               upon
               the
               by
               ,
               that
               you
               may
               make
               use
               of
               it
               ,
               if
               you
               think
               it
               worth
               while
               to
               do
               so
               .
               To
               whch
               I
               shall
               here
               present
               you
               with
               no
               Inducements
               ,
               
               since
               I
               perceive
               that
               the
               Particulars
               above
               mention'd
               about
               simple
               preparations
               of
               Gold
               and
               other
               Metals
               ,
               have
               already
               made
               this
               Section
               enormously
               great
               .
               And
               yet
               I
               hope
               you
               will
               not
               be
               displeas'd
               at
               it
               ;
               since
               to
               so
               sugacious
               a
               person
               as
               Dr.
               F.
               these
               passages
               may
               afford
               some
               not
               altogether
               useless
               hints
               :
               and
               at
               least
               't
               is
               an
               Encouragement
               to
               Industry
               ,
               to
               know
               that
               the
               subjects
               a
               man
               works
               on
               are
               capable
               of
               affording
               Excellent
               things
               .
            
          
           
             
               §.
               VII
               .
            
             
               1.
               
               I
               Foresee
               it
               may
               be
               objected
               against
               the
               frequent
               use
               of
               simple
               Medicines
               ,
               that
               oftentimes
               it
               happens
               that
               a
               Disease
               ,
               or
               a
               
                 morbisick
                 Matter
              
               ,
               is
               not
               the
               effect
               of
               a
               single
               Cause
               ,
               but
               is
               produc'd
               by
               the
               concurrence
               of
               two
               ,
               or
               perhaps
               more
               ,
               Causes
               ,
               which
               producing
               several
               symptoms
               ,
               't
               is
               not
               probable
               that
               one
               Simple
               Drag
               will
               be
               able
               to
               answer
               those
               different
               Indications
               
               This
               Objection
               I
               confess
               is
               considerable
               ,
               &
               there
               are
               cases
               wherein
               I
               acknowledg
               it
               to
               be
               so
               weighty
               as
               to
               invite
               &
               warrant
               a
               Physician
               ,
               to
               imploy
               in
               them
               a
               Medicine
               consisting
               of
               more
               Ingredients
               than
               one
               or
               two
               ;
               which
               I
               can
               admit
               without
               prejudice
               to
               any
               Design
               ,
               since
               I
               formerly
               declar'd
               I
               did
               not
               intend
               to
               perswade
               you
               to
               consine
               your self
               to
               Simple
               Remedy's
               (
               so
               much
               as
               in
               the
               late
               sense
               above
               intimated
               of
               that
               Term
               )
               but
               only
               to
               imploy
               them
               where
               they
               may
               suffice
               ;
               and
               where
               they
               cannot
               to
               make
               use
               of
               Medicines
               as
               little
               compounded
               as
               the
               case
               will
               permit
               ,
            
             
               2.
               
               But
               having
               premis'd
               this
               Advertisement
               ,
               I
               presume
               I
               may
               offer
               you
               two
               or
               three
               considerations
               ,
               that
               may
               lessen
               the
               force
               of
               the
               lately
               propos'd
               objection
               And
               first
               ,
               tho
               I
               readily
               grant
               ,
               that
               there
               are
               Diseases
               ,
               whereof
               each
               may
               proceed
               from
               differring
               causes
               ,
               and
               that
               a
               Remedy
               may
               be
               available
               against
               it
               ,
               When
               't
               is
               produc'd
               by
               one
               of
               those
               
               causes
               ,
               without
               being
               so
               when
               it
               flows
               from
               another
               ;
               yet
               it
               may
               also
               easily
               happen
               ,
               that
               in
               one
               case
               the
               Disease
               may
               be
               cur'd
               by
               one
               simple
               Medicine
               ,
               and
               in
               another
               ,
               by
               a
               Remedy
               not
               compounded
               .
               Nay
               ,
               it
               may
               also
               happen
               ,
               that
               the
               same
               simple
               may
               cure
               a
               Distemper
               ,
               by
               which
               soever
               OF
               the
               two
               causes
               it
               is
               produe'd
               .
               This
               I
               have
               in
               another
               Paper
               endeavour'd
               to
               make
               out
               .
               And
               what
               we
               see
               of
               the
               Effects
               of
               the
               
                 Jesuits
                 Powder
              
               ,
               as
               they
               call
               it
               in
               different
               kinds
               of
               Agues
               ,
               as
               
                 Tertians
                 ,
                 Quartans
                 ,
                 &c.
              
               and
               of
               pacating
               Medicines
               (
               most
               of
               which
               indeed
               owe
               their
               vertue
               to
               Opium
               ,
               but
               some
               are
               Mineral
               ,
               and
               have
               nothing
               of
               the
               Poppy
               in
               them
               )
               in
               appeasing
               Pains
               produc'd
               by
               Humours
               ,
               and
               other
               causes
               very
               differing
               ;
               may
               keep
               what
               has
               been
               said
               from
               appearing
               improbable
               ,
               And
               ,
               if
               I
               mistake
               not
               ,
               it
               may
               divers
               times
               happen
               ,
               that
               ,
               whatever
               it
               were
               that
               at
               first
               produc'd
               a
               portion
               of
               Morbisick
               matter
               ,
               that
               first
               produc'd
               matter
               ,
               is
               the
               cause
               of
               the
               continuance
               of
               the
               Disease
               ,
               
               by
               vertue
               of
               some
               peculiar
               Texture
               or
               Noxious
               Constitution
               ,
               which
               if
               a
               generous
               Medicine
               can
               destroy
               ,
               the
               Disease
               will
               ,
               at
               least
               little
               by
               little
               ,
               cease
               .
            
             
               3.
               
               It
               not
               unfrequently
               happens
               ,
               that
               several
               Symptoms
               that
               seem
               very
               differing
               ,
               may
               so
               depend
               upon
               the
               primary
               or
               principal
               cause
               of
               the
               Disease
               ,
               that
               if
               a
               Medicine
               ,
               how
               simple
               soever
               ,
               be
               capable
               to
               destroy
               that
               cause
               ,
               all
               the
               various
               Symptoms
               will
               ,
               by
               degrees
               at
               least
               ,
               vanish
               of
               themselves
               :
               as
               we
               often
               see
               ,
               that
               when
               Mercury
               ,
               tho
               perhaps
               but
               crude
               ,
               is
               skilfully
               apply'd
               ,
               and
               raises
               a
               kindly
               salivation
               ,
               a
               great
               variety
               of
               Inconveniencies
               that
               afflicted
               a
               Venereal
               Patient
               ,
               and
               seem'd
               to
               require
               many
               differing
               and
               topical
               Applications
               ,
               are
               remov'd
               by
               the
               same
               Remedy
               ;
               insomuch
               that
               not
               only
               frightful
               Ulcers
               ,
               but
               such
               Modes
               as
               one
               would
               think
               searce
               possible
               to
               be
               dissipated
               by
               the
               strongest
               Plaisters
               ,
               are
               sometimes
               happily
               cur'd
               by
               well
               prepar'd
               Quicksilver
               ,
               taken
               in
               at
               the
               mouth
               ,
               
               as
               I
               have
               been
               assured
               by
               more
               than
               one
               eminent
               Physician
               upon
               his
               own
               Experience
               ,
               And
               tho
               not
               unfrequently
               there
               be
               several
               ,
               &
               sometimes
               very
               different
               Symptoms
               ,
               that
               accompany
               that
               Disease
               of
               children
               that
               in
               England
               we
               call
               the
               Rickets
               ;
               (
               and
               of
               which
               there
               dye
               several
               almost
               every
               week
               in
               London
               alone
               )
               ▪
               yet
               that
               Medicine
               which
               I
               have
               elsewhere
               describ'd
               under
               the
               name
               of
               
                 Ens
                 (
                 primum
                 )
                 Veneris
              
               [
               made
               of
               strongly
               calcin'd
               and
               well
               dulcify'd
               
                 Colcothar
                 of
                 Dantsick
                 Vitriol
              
               ,
               and
               elevated
               with
               
                 Sal
                 Armoniack
              
               into
               the
               form
               of
               a
               reddish
               sublimate
               ]
               has
               prov'd
               ,
               by
               Gods
               blessing
               on
               it
               ,
               so
               successful
               ,
               that
               partly
               by
               a
               Sister
               of
               mine
               ,
               (
               to
               whom
               I
               communicated
               it
               )
               and
               partly
               by
               my self
               ,
               and
               those
               I
               directed
               to
               take
               it
               ,
               or
               to
               give
               it
               ;
               I
               think
               I
               may
               safely
               say
               ,
               that
               two
               or
               three
               hundred
               children
               have
               been
               cur'd
               by
               it
               ,
               and
               that
               almost
               always
               without
               the
               help
               of
               any
               other
               inward
               Medicine
               ,
               or
               using
               any
               Topical
               application
               at
               all
               .
            
             
             
               4.
               
               But
               the
               main
               thing
               that
               I
               intended
               ,
               by
               way
               of
               answer
               to
               the
               foreseen
               Objection
               ,
               was
               ,
               that
               in
               a
               simple
               Medince
               nature
               her self
               does
               oftentimes
               so
               well
               play
               the
               Apothecary
               ,
               as
               to
               render
               the
               compositions
               made
               in
               his
               shop
               unnecessary
               .
               For
               ,
               tho
               we
               are
               wont
               to
               look
               upon
               this
               or
               that
               Plant
               or
               Mineral
               ,
               as
               an
               entire
               and
               simple
               Body
               ,
               yet
               we
               may
               much
               mistake
               ,
               if
               we
               look
               upon
               it
               as
               a
               Homogeneous
               one
               .
               In
               several
               Plants
               that
               are
               organical
               Bodies
               ,
               this
               Truth
               is
               manifest
               ;
               as
               for
               instance
               ,
               in
               Oranges
               the
               Succulent
               part
               is
               soure
               and
               cooling
               ,
               but
               the
               
                 Yellow
                 Rind
              
               considerably
               bitter
               and
               hot
               :
               and
               so
               in
               Lemons
               the
               Pulp
               ,
               the
               Yellow
               part
               of
               the
               Rind
               ,
               and
               the
               seeds
               have
               their
               differing
               Qualities
               and
               Medicinal
               vertues
               .
               And
               even
               in
               such
               vegetable
               Substances
               as
               are
               Homogeneous
               as
               to
               sense
               ,
               there
               may
               be
               Parts
               ,
               whose
               operations
               may
               be
               not
               only
               differing
               ,
               but
               contrary
               ;
               as
               is
               manifest
               in
               the
               Root
               ,
               we
               call
               Rhubarb
               ,
               which
               affords
               as
               well
               notably
               Astringent
               ,
               as
               Laxative
               and
               
               Purgative
               Parts
               .
               And
               so
               in
               Minerals
               themselves
               good
               and
               clean
               Lead-Oar
               ,
               for
               instance
               ,
               tho
               an
               uniform
               body
               as
               to
               sense
               ,
               consists
               of
               very
               dissimilar
               Parts
               ,
               and
               affords
               Sulphureous
               and
               perhaps
               other
               Recrements
               ,
               besides
               Malleable
               Lead
               ,
               which
               is
               it self
               a
               compounded
               Body
               .
               Thus
               also
               shining
               Marcasites
               ,
               tho
               they
               appear
               Homogeneous
               ,
               will
               by
               barely
               being
               expos'd
               for
               a
               competent
               time
               to
               the
               moist
               Air
               ,
               afford
               an
               Efflorescence
               ,
               that
               is
               perfectly
               vitriolate
               ,
               and
               consequently
               contains
               an
               Acid
               Salt
               ,
               two
               kinds
               of
               Sulphur
               ,
               a
               Terrestrial
               Substance
               ,
               and
               at
               least
               one
               Metal
               ,
               (
               for
               oftentimes
               it
               holds
               both
               Copper
               and
               Iron
               ,
               tho
               one
               predominate
               ,
               )
               which
               last
               nam'd
               Substances
               themselves
               are
               neither
               of
               them
               simple
               Bodies
               .
            
             
               5.
               
               And
               if
               we
               admit
               the
               Chymical
               Analysis
               of
               mixts
               to
               be
               genuine
               ,
               we
               shall
               find
               that
               almost
               all
               those
               that
               belong
               to
               the
               Vegetable
               Kingdom
               ,
               or
               to
               the
               Animal
               ,
               and
               many
               that
               are
               refer'd
               to
               the
               Mineral
               Kingdom
               ,
               how
               uniform
               soever
               they
               may
               appear
               to
               
               the
               Eye
               ,
               do
               each
               of
               them
               contain
               several
               different
               ,
               and
               sometimes
               hostile
               Substances
               .
               Thus
               Hartshorn
               ,
               tho
               it
               appears
               a
               dry
               and
               Homogeneous
               Substance
               ,
               will
               in
               distillation
               afford
               a
               volatile
               Salt
               ,
               an
               urinous
               Spirit
               ,
               a
               waterish
               Liquor
               ,
               or
               Phlegm
               ,
               a
               swiming
               Oyl
               and
               a
               sinking
               one
               ,
               a
               white
               and
               porous
               Earth
               ,
               or
               
                 Terra
                 damnata
              
               ,
               and
               perhaps
               some
               ,
               tho
               but
               very
               little
               ,
               fixt
               Salt.
               Thus
               also
               in
               the
               Vegetable
               Kingdom
               ,
               Tartar
               ,
               for
               instance
               ,
               may
               without
               addition
               be
               made
               to
               afford
               ,
               as
               Experience
               hath
               assur'd
               me
               ,
               a
               volatile
               Salt
               very
               like
               that
               of
               Urine
               ,
               a
               Phlegme
               ,
               an
               Acid
               Spirit
               ,
               another
               Spirit
               too
               which
               I
               have
               elsewhere
               given
               the
               name
               of
               Adiaphorous
               ,
               two
               faetid
               Oyls
               ,
               whereof
               one
               will
               sink
               in
               Water
               ,
               and
               the
               other
               swim
               on
               it
               ,
               an
               Earth
               or
               
                 Terra
                 Damnata
              
               ,
               and
               a
               fixt
               Lixivial
               Salt
               ,
               upon
               which
               the
               newly
               mention'd
               Acid
               Spirit
               manifests
               such
               a
               hostility
               ,
               that
               when
               they
               are
               put
               together
               ,
               they
               tumultuate
               with
               noise
               and
               Bubbles
               ,
               and
               
               in
               the
               Conflict
               mortify
               each
               other
               .
               And
               thus
               likewise
               in
               the
               Mineral
               Kingdom
               ,
               not
               to
               repeat
               what
               I
               lately
               said
               of
               the
               compoundedness
               of
               Vitriol
               ;
               Nor
               confidently
               to
               urge
               the
               Opinion
               of
               divers
               Eminent
               Physicians
               ,
               that
               Mars
               (
               as
               they
               call
               Steel
               and
               Iron
               )
               affords
               parts
               whereof
               some
               are
               Astringent
               ,
               and
               other
               Operative
               ,
               because
               I
               am
               not
               yet
               sure
               these
               contrary
               qualitys
               ,
               do
               not
               proceed
               from
               the
               differing
               degrees
               of
               Fire
               ,
               and
               other
               Circumstances
               of
               the
               preparations
               of
               the
               Metal
               :
               We
               see
               that
               
                 Native
                 Cinnabar
              
               affords
               by
               Distillation
               ,
               besides
               running
               Mercury
               ,
               a
               dry
               substance
               ,
               whence
               I
               have
               obtain'd
               a
               Sulphur
               that
               would
               presently
               gild
               Silver
               ,
               and
               a
               Terrestrial
               substance
               ,
               whose
               nature
               I
               had
               not
               occasion
               to
               examine
               .
               And
               I
               the
               rather
               take
               notice
               of
               these
               differing
               Parts
               in
               
                 Native
                 Cinnabar
              
               ,
               because
               it
               is
               a
               Mineral
               that
               I
               much
               esteem
               ;
               and
               tho
               here
               in
               England
               it
               is
               very
               rarely
               ,
               or
               scarce
               at
               all
               imploy'd
               as
               an
               inward
               Medicine
               ,
               yet
               I
               know
               some
               
               Forraign
               Physicians
               of
               several
               Nations
               ,
               that
               look
               upon
               it
               ,
               as
               one
               of
               their
               chief
               Arcanums
               ,
               and
               both
               use
               it
               ,
               and
               conceal
               it
               ,
               accordingly
               .
               But
               I
               do
               not
               willingly
               imploy
               it
               ,
               till
               it
               has
               been
               prepar'd
               ,
               by
               grinding
               it
               exactly
               ,
               upon
               a
               Porphire
               ,
               or
               other
               fit
               Stone
               ,
               as
               a
               Painter
               would
               do
               to
               make
               a
               Pigment
               of
               it
               ,
               and
               by
               freeing
               it
               from
               certain
               Salts
               ,
               that
               often
               undiscernedly
               adhere
               to
               it
               ,
               and
               sometimes
               may
               be
               hurtful
               ;
               which
               is
               done
               by
               First
               washing
               it
               very
               carefully
               with
               boyling
               Water
               ,
               and
               then
               ,
               after
               it
               has
               been
               throughly
               dry'd
               ,
               by
               burning
               upon
               it
               several
               times
               ,
               one
               after
               another
               ,
               some
               Vinous
               Spirits
               perfectly
               dephlegm'd
               .
               [
               The
               Dose
               ,
               if
               it
               be
               to
               be
               long
               continu'd
               ,
               may
               be
               three
               ,
               four
               or
               five
               grains
               :
               but
               when
               't
               is
               to
               be
               given
               but
               seldom
               ,
               and
               for
               an
               urgent
               Case
               ,
               it
               may
               be
               from
               six
               or
               seven
               ,
               to
               ten
               or
               twelve
               grains
               .
            
          
           
             
             
               §.
               VIII
               .
            
             
               1.
               
               WHat
               has
               been
               said
               in
               the
               foregoing
               discourse
               ,
               to
               manifest
               ,
               that
               a
               simple
               ,
               whether
               Organical
               or
               not
               ,
               may
               notwithstanding
               its
               intireness
               or
               its
               seeming
               Homogeneity
               ,
               contain
               or
               afford
               very
               ,
               dissimilar
               parts
               ;
               may
               help
               us
               to
               conceive
               ,
               that
               being
               really
               a
               compounded
               Body
               ,
               it
               may
               afford
               Parts
               differing
               enough
               to
               answer
               differing
               Indications
               ,
               or
               attain
               several
               Scopes
               ,
               that
               are
               wont
               to
               be
               look'd
               on
               by
               Physiciaus
               as
               necessary
               ,
               or
               at
               least
               very
               useful
               to
               the
               cure
               of
               this
               or
               that
               disease
               ;
               as
               in
               many
               Diarrhaeas
               or
               Fluxes
               of
               the
               Belly
               ,
               whereas
               ,
               't
               is
               judg'd
               requisite
               first
               to
               evacuate
               the
               Peccant
               matter
               ,
               and
               then
               to
               give
               Astringents
               ,
               to
               hinder
               the
               immoderate
               evacuation
               wherein
               the
               disease
               is
               thought
               to
               consist
               ;
               Rhubarb
               answers
               both
               those
               Indications
               ,
               by
               its
               Purgative
               and
               its
               more
               terrestrial
               
               Parts
               ,
               whereof
               the
               former
               dispatch
               their
               work
               first
               ,
               which
               makes
               the
               Astringent
               operation
               of
               the
               latter
               seasonable
               and
               safe
               .
            
             
               2.
               
               I
               have
               divers
               times
               observ'd
               ,
               that
               so
               common
               and
               despicable
               a
               simple
               as
               
                 Ground
                 Ivy
              
               ,
               has
               perform'd
               things
               whose
               variety
               seem'd
               to
               argue
               ,
               that
               it
               contains
               Parts
               of
               very
               differing
               vertues
               (
               as
               of
               opening
               ,
               contemperating
               ,
               healing
               ,
               &c.
               )
               and
               is
               thereby
               capable
               of
               answering
               differing
               intentions
               ,
               especially
               in
               Distempers
               of
               the
               Lungs
               &
               Breast
               ,
               &
               indeed
               partly
               by
               the
               Syrup
               of
               it
               ,
               partly
               by
               the
               infusion
               of
               the
               Leaves
               ,
               and
               partly
               by
               Medicines
               made
               of
               them
               in
               a
               consistent
               form
               ;
               the
               happy
               Effects
               of
               this
               simple
               have
               procur'd
               me
               the
               thanks
               of
               divers
               considerable
               persons
               ,
               some
               of
               which
               had
               before
               unsuccesfully
               us'd
               many
               Prescriptions
               of
               learned
               men
               .
               And
               I
               remember
               I
               knew
               an
               Ingenious
               Person
               ,
               who
               being
               Master
               of
               a
               considerable
               manufacture
               ,
               which
               was
               gainful
               to
               him
               ,
               whilst
               his
               Servants
               continu'd
               tolerably
               
               well
               ,
               was
               very
               much
               incommodated
               and
               perplex'd
               ,
               to
               find
               them
               so
               obnoxious
               to
               violent
               Colicks
               ,
               (
               which
               he
               imputed
               to
               the
               Copious
               Steams
               of
               the
               Vinegar
               his
               Art
               requir'd
               ,
               )
               that
               he
               was
               forc'd
               almost
               weekly
               to
               allow
               them
               some
               days
               of
               cessation
               from
               working
               ,
               to
               preserve
               or
               recover
               themselves
               .
               And
               I
               remember
               that
               from
               this
               Inconvenience
               ,
               he
               was
               at
               length
               ,
               as
               himself
               confess'd
               to
               me
               ,
               in
               great
               part
               freed
               by
               making
               his
               workmen
               frequently
               use
               a
               strong
               Infusion
               or
               Tincture
               of
               the
               Leaves
               of
               our
               ground-Ivy
               made
               with
               (
               not
               pure
               or
               dephlegm'd
               Spirit
               of
               Wine
               ,
               but
               )
               good
               unrectify'd
               Nants
               Brandy
               .
            
             
               I
               could
               here
               add
               divers
               other
               uses
               ,
               both
               Internal
               and
               External
               ,
               of
               this
               seemingly
               despicable
               Plant
               ,
               there
               being
               scarce
               any
               one
               English
               Herb
               known
               to
               me
               ,
               of
               which
               ,
               for
               its
               manifest
               vertues
               ,
               the
               Experience
               of
               others
               and
               my
               own
               have
               given
               me
               a
               greater
               Esteem
               .
               And
               I
               am
               apt
               to
               think
               ,
               that
               the
               Efficacy
               which
               this
               and
               some
               other
               Simples
               ,
               that
               the
               
               fear
               of
               Prolixity
               makes
               me
               silently
               pass
               by
               ,
               would
               be
               found
               both
               greater
               and
               more
               various
               than
               they
               are
               commonly
               thought
               ,
               if
               Physicians
               in
               prescribing
               Medicines
               would
               more
               often
               either
               ordain
               Simple
               ones
               ,
               or
               at
               least
               associate
               but
               very
               few
               together
               ,
               and
               compensate
               the
               small
               number
               of
               Ingredients
               ,
               by
               the
               greater
               quantity
               of
               those
               that
               are
               the
               most
               appropriated
               or
               operative
               ,
               and
               by
               persisting
               in
               their
               use
               for
               a
               competent
               time
               .
            
             
               Tho
               't
               is
               not
               every
               efficacious
               Simple
               ,
               or
               but
               lightly
               compounded
               Remedy
               ,
               that
               can
               fitly
               be
               imploy'd
               about
               the
               Proof
               of
               what
               I
               am
               now
               endeavouring
               to
               show
               ,
               yet
               I
               shall
               subjoyn
               such
               Instances
               ,
               as
               will
               ,
               I
               hope
               ,
               suffice
               for
               the
               present
               Occasion
               .
            
             
               Mineral
               Waters
               ,
               as
               well
               Acidubae
               ,
               as
               the
               
                 German
                 Spaw
              
               ,
               our
               Tunbridge
               ,
               &c.
               as
               Thermae
               ,
               such
               as
               those
               of
               Bath
               ,
               &c
               ,
               tho
               but
               Natural
               Medicines
               ;
               and
               some
               of
               them
               but
               outwardly
               administred
               ,
               are
               notoriously
               known
               in
               their
               native
               simplicity
               to
               be
               able
               
               one
               of
               them
               single
               ,
               frequently
               to
               cure
               several
               Diseases
               ,
               and
               consequently
               to
               take
               off
               a
               good
               number
               of
               differing
               Symptoms
               ,
               that
               afford
               various
               Indications
               .
               It
               may
               help
               much
               to
               make
               it
               probable
               that
               the
               same
               Simple
               may
               comprise
               Qualities
               fit
               to
               answer
               differing
               Scopes
               ,
               and
               thereby
               cure
               differing
               Symptoms
               ,
               if
               it
               be
               consider'd
               ,
               that
               there
               are
               several
               Poysons
               that
               do
               each
               of
               them
               produce
               Symptoms
               not
               only
               very
               frightful
               ,
               but
               very
               various
               ,
               and
               yet
               all
               these
               have
               been
               oftentimes
               conquer'd
               by
               a
               Specifick
               Antidote
               ,
               that
               is
               perhaps
               but
               a
               simple
               Herb
               or
               other
               uncompounded
               Drug
               .
               I
               had
               once
               ,
               (
               and
               but
               once
               )
               the
               opportunity
               of
               making
               a
               Tryal
               ,
               whereof
               I
               shall
               now
               give
               you
               a
               brief
               Account
               ,
               of
               the
               vertue
               of
               a
               stone
               taken
               out
               of
               the
               Head
               of
               an
               enormously
               great
               African
               Serpent
               ;
               which
               stone
               was
               affirm'd
               to
               the
               Possessor
               of
               it
               ,
               Governour
               of
               the
               famous
               English
               
                 East
                 India
                 Company
              
               ,
               to
               be
               highly
               available
               against
               the
               Bitings
               of
               all
               venemous
               Animals
               .
               
               The
               substance
               of
               the
               Experiment
               (
               to
               give
               it
               you
               in
               short
               )
               was
               this
               ,
               I
               caus'd
               a
               young
               Cat
               to
               be
               bitten
               by
               a
               fierce
               and
               highly
               irritated
               Viper
               ,
               which
               so
               inrag'd
               the
               Cat
               ,
               that
               in
               revenge
               he
               endeavour'd
               to
               bite
               off
               her
               Head
               ,
               which
               he
               took
               in
               his
               Mouth
               ,
               and
               did
               not
               let
               go
               ,
               till
               ,
               as
               the
               Spectators
               concluded
               ,
               she
               had
               bit
               him
               again
               ,
               at
               ,
               least
               by
               the
               tongue
               ;
               soon
               after
               which
               venemous
               Hurt
               ,
               the
               Cats
               Head
               swell'd
               very
               much
               ,
               and
               tho
               he
               soon
               grew
               so
               weak
               ,
               that
               he
               was
               not
               able
               to
               stand
               on
               his
               Legs
               ,
               but
               lay
               along
               on
               the
               ground
               ,
               yet
               he
               seem'd
               to
               be
               grown
               quite
               mad
               ,
               for
               he
               foam'd
               at
               the
               Mouth
               ,
               and
               snapt
               at
               the
               end
               of
               a
               Wand
               ,
               or
               such
               like
               things
               ,
               that
               were
               but
               held
               near
               him
               ;
               and
               ,
               which
               was
               more
               ,
               in
               his
               rage
               bit
               one
               of
               his
               own
               Legs
               ,
               that
               lay
               not
               far
               from
               his
               Mouth
               ,
               much
               to
               the
               surprise
               of
               the
               Spectators
               .
               But
               ,
               tho
               in
               this
               desperate
               condition
               it
               seem'd
               in
               vain
               to
               attempt
               any
               thing
               for
               his
               Rescue
               ,
               because
               one
               could
               make
               him
               take
               nothing
               ,
               and
               every
               one
               was
               affraid
               
               to
               come
               near
               him
               ;
               yet
               having
               mix'd
               a
               little
               of
               the
               powder'd
               stone
               with
               some
               sponfuls
               of
               fair
               Water
               ,
               it
               was
               by
               the
               help
               of
               the
               neck
               of
               a
               glass
               Retort
               ,
               that
               we
               imploy'd
               in
               stead
               of
               a
               funnel
               ,
               pour'd
               by
               degrees
               upon
               the
               Cats
               Mouth
               ;
               which
               lying
               open
               ,
               tho
               he
               endeavour'd
               to
               shake
               it
               off
               ,
               yet
               some
               of
               it
               was
               concluded
               to
               have
               got
               in
               ;
               and
               within
               one
               hour
               or
               two
               after
               ,
               if
               not
               less
               ,
               he
               did
               ,
               to
               the
               no
               small
               wonder
               of
               the
               By-standers
               ,
               get
               upon
               his
               Legs
               again
               ,
               and
               not
               only
               seem'd
               to
               have
               much
               of
               the
               Tumidness
               of
               his
               Head
               ,
               but
               readily
               enough
               took
               the
               Medicine
               I
               caus'd
               to
               be
               given
               him
               ;
               and
               would
               probably
               have
               scap'd
               very
               well
               ,
               if
               ,
               whilst
               I
               was
               at
               dinner
               with
               the
               Company
               ,
               some
               unruly
               People
               had
               not
               hurt
               him
               more
               mortally
               than
               the
               Viper
               had
               done
               .
            
             
               Physicians
               and
               others
               have
               observ'd
               in
               the
               Plague
               a
               great
               variety
               of
               Symptoms
               ,
               among
               which
               there
               are
               divers
               ,
               whereof
               each
               ,
               if
               single
               would
               psas
               for
               a
               particular
               Disease
               .
               And
               this
               
               diversity
               of
               Symptoms
               may
               be
               not
               unfrequently
               observ'd
               ,
               not
               only
               in
               Pestilences
               that
               happen
               at
               times
               ,
               or
               in
               Countries
               distant
               from
               one
               another
               ,
               but
               in
               the
               same
               Plague
               reigning
               in
               the
               same
               Place
               .
               And
               yet
               't
               is
               possible
               ,
               that
               a
               simple
               Remedy
               may
               be
               available
               against
               this
               so
               multifarious
               or
               manifold
               (
               if
               I
               may
               so
               call
               it
               )
               and
               violent
               a
               Disease
               .
               Of
               Which
               Observation
               (
               to
               omit
               what
               might
               be
               alledg'd
               out
               of
               some
               other
               Authors
               )
               I
               shall
               give
               one
               instance
               out
               of
               Galen
               himself
               ,
               who
               ,
               treating
               at
               large
               of
               the
               
                 Terra
                 Samia
              
               ,
               takes
               occasion
               'to
               bring
               in
               the
               vertues
               of
               Bolarmony
               (
               
                 Bolus
                 Armena
              
               )
               which
               I
               should
               guess
               by
               his
               manner
               of
               mentioning
               it
               to
               have
               been
               little
               ,
               if
               at
               all
               ,
               known
               to
               Physicians
               till
               his
               Time.
               This
               Earth
               ,
               that
               appears
               a
               Body
               so
               simple
               and
               uniform
               ;
               He
               not
               only
               commends
               for
               sevearal
               Diseases
               ,
               as
               spitting
               of
               Blood
               ,
               Fluxes
               of
               the
               Belly
               ,
               Dysenteries
               Catarrhs
               ,
               Defluxions
               from
               the
               Head
               upon
               the
               Breast
               ,
               Difficulty
               of
               Breathing
               thence
               insuing
               ,
               
               and
               even
               Ulcers
               of
               the
               Lungs
               ;
               but
               adds
               ,
               what
               makes
               very
               much
               and
               directly
               for
               our
               purpose
               ,
               in
               the
               following
               words
               .
               
                 In
                 magna
                 hac
                 Peste
              
               ,
               
               (
               whereof
               he
               had
               spoken
               before
               )
               
                 cujus
                 eadem
                 facies
                 fuit
                 atque
                 ejus
                 quae
                 Thucidydis
                 memoria
                 grassabatur
                 ,
                 quotquot
                 hoc
                 Medicamen
                 bibere
                 celeriter
                 curati
                 sunt
                 .
              
               [
               The
               way
               of
               giving
               it
               (
               which
               I
               add
               by
               the
               by
               ,
               because
               it
               may
               sometime
               or
               other
               be
               of
               use
               )
               was
               this
               ,
               Bibitur
               ,
               says
               He
               ,
               
                 ex
                 vino
                 albo
                 consistentiâ
                 tenui
                 ,
                 modice
                 diluto
                 ,
                 si
                 aut
                 planè
                 Febri
                 careat
                 ,
                 aut
                 leviter
                 eâ
                 teneatur
                 ,
                 sin
                 gravius
                 febriat
                 ,
                 admodum
                 aqueo
                 .
              
               ]
               And
               so
               excellent
               a
               Medicine
               did
               this
               simple
               one
               prove
               in
               that
               terrible
               Plague
               ,
               that
               our
               Author
               sayes
               ,
               
                 Quibus
                 non
                 profuit
                 omnes
                 interiere
              
               ;
               Scil.
               
                 cum
                 nec
                 alio
                 quovis
                 Medicamine
                 ,
                 juvarentur
                 :
                 unde
                 colligiter
                 ,
              
               concludes
               He
               ,
               
                 quòd
                 iis
                 duntaxat
                 non
                 fuerit
                 auxilio
                 qui
                 plane
                 erant
                 incurabiles
                 .
              
            
             
               3.
               
               There
               are
               few
               Diseases
               that
               put
               on
               so
               many
               forms
               ,
               or
               are
               attended
               
               with
               greater
               variety
               of
               Symptoms
               ,
               than
               that
               which
               Physicians
               call
               
                 Affectio
                 Hysterica
              
               ,
               and
               whose
               Paroxysus
               or
               effects
               are
               vulgarly
               known
               in
               England
               by
               the
               name
               of
               
                 Fits
                 of
                 the
                 Mother
              
               .
               And
               yet
               we
               have
               often
               remov'd
               ,
               and
               not
               seldom
               in
               a
               quarter
               of
               an
               hour
               or
               less
               ,
               
                 Hysterical
                 Paroxysus
              
               and
               Symptoms
               ,
               and
               sometimes
               such
               as
               made
               the
               Patient
               swoon
               or
               lye
               along
               as
               almost
               dead
               ,
               by
               the
               bare
               Odour
               ,
               of
               well
               rectify'd
               
                 Spirt
                 of
                 Harts-horn
              
               ,
               or
               the
               mere
               pungent
               and
               powerful
               smell
               of
               a
               
                 Spirit
                 of
                 Sal
                 Armoniack
              
               ,
               which
               by
               a
               peculiar
               way
               I
               made
               very
               strong
               ,
               purposely
               for
               external
               Uses
               .
               And
               if
               I
               had
               not
               out
               of
               the
               experienc'd
               Monardes
               ,
               
               Physician
               to
               the
               Viceroy
               of
               the
               
                 Spanish
                 Indies
              
               ,
               already
               mention'd
               in
               another
               Treatise
               an
               Antiscorbutical
               Gem
               ;
               I
               would
               here
               add
               another
               Remedy
               against
               the
               same
               Disease
               ,
               more
               considerable
               to
               my
               present
               purpose
               ,
               since
               't
               is
               only
               a
               simple
               Stone
               outwardly
               apply'd
               .
            
             
             
               4.
               
               But
               ,
               because
               I
               think
               not
               fit
               in
               this
               place
               to
               insist
               on
               a
               Testimony
               already
               alledg'd
               ,
               tho
               its
               Credibility
               ,
               as
               well
               as
               that
               of
               the
               thing
               to
               be
               confirm'd
               by
               it
               ,
               may
               be
               much
               favour'd
               by
               what
               has
               been
               related
               ,
               concerning
               the
               Vertues
               of
               Stones
               outwardly
               apply'd
               ,
               in
               the
               latter
               part
               of
               the
               Discourse
               about
               Specificks
               :
               For
               this
               Reason
               ,
               I
               say
               ,
               I
               shall
               add
               a
               couple
               of
               other
               remarkable
               Instances
               ,
               of
               the
               Efficacy
               of
               even
               Dry
               and
               Solid
               Bodies
               ,
               tho
               but
               externally
               apply'd
               in
               Diseases
               attended
               with
               several
               ,
               and
               divers
               of
               them
               uncommon
               Symptoms
               ,
               whereof
               ,
               whatever
               many
               think
               of
               the
               harmlessness
               of
               our
               English
               Vipers
               ,
               I
               have
               here
               known
               several
               Instances
               ,
               in
               Men
               as
               well
               as
               Brutes
               .
               And
               yet
               in
               these
               dangerous
               Cases
               ,
               many
               that
               come
               from
               
                 East
                 India
              
               extol
               the
               great
               Efficacy
               of
               some
               of
               those
               Stony
               Concretions
               ,
               that
               are
               said
               to
               be
               found
               in
               the
               Heads
               of
               a
               certain
               kind
               of
               Serpents
               about
               Goa
               ,
               and
               some
               other
               Eastern
               Countreys
               :
               for
               tho
               most
               Physicians
               reject
               or
               question
               the
               
               Power
               ascrib'd
               to
               these
               stones
               ,
               for
               curing
               the
               Bitings
               of
               Vipers
               ,
               and
               tho
               I
               do
               not
               wonder
               at
               their
               diffidence
               ,
               because
               in
               effect
               many
               of
               the
               stones
               brought
               from
               India
               are
               but
               counterfeit
               ;
               and
               of
               those
               that
               were
               really
               taken
               out
               of
               Serpents
               ,
               several
               ,
               for
               a
               Reason
               I
               must
               not
               stay
               to
               mention
               ,
               are
               insignificant
               ;
               (
               and
               such
               perhaps
               were
               those
               that
               the
               learned
               and
               curious
               Redy
               made
               his
               Tryals
               with
               )
               yet
               there
               are
               others
               ,
               whose
               vertues
               are
               not
               well
               to
               be
               deny'd
               .
               For
               ,
               not
               to
               build
               on
               vulgar
               Traditions
               ,
               which
               are
               but
               too
               often
               deceitful
               ,
               one
               of
               the
               eminentest
               Doctors
               of
               the
               
                 London
                 Colledge
              
               assur'd
               me
               ,
               that
               he
               had
               ,
               with
               one
               of
               these
               stones
               ,
               done
               ,
               tho
               contrary
               to
               his
               expectation
               ;
               a
               notable
               Cure
               ,
               which
               he
               related
               to
               me
               at
               large
               .
               And
               one
               of
               our
               chief
               English
               Chyrurgeons
               affirm'd
               to
               me
               ,
               that
               he
               had
               done
               the
               like
               upon
               another
               person
               ;
               both
               of
               these
               Cures
               being
               perform'd
               by
               the
               bare
               application
               of
               the
               Stone
               ,
               to
               the
               Place
               bitten
               by
               the
               Viper
               or
               Adder
               .
               And
               a
               very
               
               intelligent
               person
               ,
               who
               had
               the
               direction
               of
               a
               considerable
               Company
               of
               Traders
               in
               
                 East
                 India
              
               ,
               where
               he
               long
               liv'd
               ,
               assur'd
               me
               that
               he
               had
               with
               this
               Stone
               cur'd
               several
               persons
               of
               the
               Hurts
               of
               venemous
               Animals
               ,
               But
               ,
               this
               Testimony
               is
               much
               less
               considerable
               ,
               as
               to
               the
               number
               of
               Cures
               ,
               than
               that
               of
               a
               great
               Traveller
               into
               the
               Southern
               parts
               of
               the
               same
               India
               ,
               who
               ,
               tho
               he
               were
               bred
               by
               a
               famous
               Cartesian
               Philospher
               ,
               and
               were
               forward
               enough
               to
               discredit
               vulgar
               Traditions
               about
               the
               Countreys
               he
               had
               long
               liv'd
               in
               ;
               yet
               being
               for
               those
               Reasons
               ask'd
               by
               me
               ,
               what
               I
               might
               safely
               believe
               of
               the
               Stones
               I
               speak
               of
               ,
               seriously
               affirm'd
               to
               me
               ,
               that
               he
               had
               cur'd
               above
               threescore
               persons
               of
               the
               Bitings
               or
               Stings
               of
               several
               sorts
               of
               poysonus
               Creatures
               ;
               and
               that
               he
               perform
               most
               of
               those
               Cures
               ,
               by
               the
               outward
               Application
               of
               one
               Stone
               ;
               because
               ,
               finding
               it
               excellent
               ,
               He
               was
               invited
               to
               keep
               to
               it
               ,
               especially
               in
               difficult
               .
               cases
               .
               And
               this
               same
               Experience
               of
               my
               own
               ,
               made
               with
               a
               Genuine
               
               Stone
               of
               this
               kind
               ,
               upon
               the
               Bodies
               of
               Brutes
               ,
               much
               inclines
               me
               to
               give
               credit
               to
               .
               But
               ,
               because
               this
               Stone
               is
               afforded
               by
               an
               Animal
               ,
               I
               shall
               add
               the
               vertues
               of
               another
               ,
               that
               properly
               belongs
               to
               the
               Mineral
               Kingdom
               ;
               in
               a
               Disease
               ,
               whose
               Symptoms
               ,
               tho
               not
               so
               various
               ,
               are
               sometimes
               dangerous
               ,
               and
               too
               often
               mortal
               .
            
             
               To
               shew
               you
               then
               ,
               that
               in
               spite
               of
               great
               Closeness
               and
               Hardness
               ,
               a
               simple
               Remedy
               outwardly
               apply'd
               ,
               may
               be
               a
               very
               effectual
               one
               ,
               I
               shall
               inform
               you
               ,
               that
               tho
               the
               Solid
               I
               am
               speaking
               of
               past
               for
               a
               Bloodstone
               ,
               yet
               by
               its
               colour
               and
               some
               other
               visible
               qualities
               ,
               I
               should
               rather
               have
               taken
               it
               for
               an
               Agat
               .
               It
               was
               but
               about
               the
               bigness
               of
               a
               small
               Nutmeg
               ,
               and
               had
               in
               it
               a
               Perforation
               ,
               by
               which
               a
               stiring
               past
               through
               it
               ,
               to
               fasten
               it
               to
               the
               Part
               affected
               .
               This
               Stone
               had
               been
               long
               kept
               in
               the
               Family
               that
               possess'd
               it
               ,
               when
               I
               saw
               it
               ,
               being
               for
               its
               rare
               vertues
               left
               by
               one
               to
               another
               .
               But
               ,
               to
               omit
               the
               reports
               that
               
               went
               of
               it
               ,
               the
               notable
               case
               ,
               that
               makes
               it
               pertinent
               for
               me
               to
               mention
               it
               here
               ,
               was
               this
               .
               An
               ingenious
               Gentleman
               ,
               that
               was
               a
               man
               of
               Letters
               ,
               and
               when
               I
               saw
               him
               ,
               was
               in
               the
               Flower
               of
               his
               Age
               ,
               and
               of
               a
               complexion
               so
               highly
               Sanguine
               ,
               as
               is
               not
               usually
               to
               be
               met
               with
               ,
               was
               from
               time
               to
               time
               subject
               to
               Hemorrhages
               at
               the
               Nose
               ;
               so
               profuse
               and
               so
               difficult
               to
               be
               restrain'd
               ,
               that
               his
               Physician
               ,
               tho
               a
               Person
               famous
               and
               very
               well
               skill'd
               in
               his
               Art
               ,
               told
               me
               he
               often
               fear'd
               he
               should
               loose
               his
               Patient
               ,
               and
               that
               he
               would
               be
               carry'd
               away
               by
               this
               unbridled
               Distemper
               ▪
               But
               when
               good
               method
               and
               variety
               of
               Remedies
               had
               been
               try'd
               ,
               without
               the
               desir'd
               success
               ,
               this
               Stone
               was
               at
               length
               obtain'd
               from
               an
               ancient
               Kinswoman
               of
               the
               Gentlemans
               ,
               to
               tye
               about
               his
               Neck
               ,
               so
               as
               to
               touch
               his
               naked
               Skin
               .
               This
               when
               he
               did
               in
               the
               Fits
               ,
               it
               would
               stop
               the
               Bleeding
               ;
               and
               if
               he
               wore
               it
               for
               some
               considerable
               time
               together
               ,
               he
               all
               that
               while
               continu'd
               well
               ,
               as
               both
               his
               learned
               
               Physician
               and
               himself
               inform'd
               me
               .
               And
               ,
               because
               I
               was
               apt
               to
               ascribe
               somewhat
               of
               this
               effect
               to
               imagination
               ,
               on
               ,
               the
               Patient
               told
               me
               ,
               that
               a
               while
               before
               one
               of
               the
               chief
               Women
               in
               the
               City
               ,
               (
               whom
               he
               nam'd
               to
               me
               )
               fell
               into
               so
               violent
               a
               Bleedings
               ,
               that
               ,
               tho'
               it
               brought
               her
               into
               a
               Swoon
               ,
               yet
               that
               it self
               ,
               which
               is
               somewhat
               strange
               ,
               did
               not
               hinder
               her
               to
               Bleed
               on
               ,
               till
               the
               Stone
               ,
               having
               been
               ty'd
               about
               her
               Neck
               ,
               made
               her
               cease
               to
               do
               so
               ,
               tho'
               she
               knew
               nothing
               of
               its
               having
               been
               apply'd
               to
               her
               .
               And
               this
               it self
               is
               less
               strange
               than
               what
               the
               Gentleman
               affirm'd
               to
               me
               of
               the
               Power
               of
               this
               Gem
               ,
               as
               it
               may
               deservedly
               be
               called
               .
               For
               his
               complexion
               inclining
               him
               ,
               as
               was
               above
               intimaed
               ,
               to
               breed
               great
               store
               of
               Blood
               ,
               his
               Doctor
               thought
               fit
               to
               order
               him
               ,
               for
               prevention
               ,
               to
               breath
               a
               Vein
               ,
               from
               time
               to
               time
               ,
               which
               when
               he
               was
               about
               to
               do
               ,
               he
               was
               obliged
               to
               lay
               aside
               the
               Stone
               for
               a
               while
               ,
               because
               ,
               whilst
               he
               kept
               it
               on
               ,
               the
               Blood
               would
               not
               issue
               out
               ,
               at
               least
               with
               the
               requisite
               Freedom
               .
            
             
             
               But
               how
               far
               have
               I
               already
               past
               beyond
               the
               designed
               Limits
               of
               this
               little
               Tract
               !
               wherein
               I
               at
               first
               intended
               ,
               but
               to
               lay
               before
               you
               the
               five
               chief
               advantages
               I
               had
               observ'd
               ,
               mere
               simple
               Remedies
               to
               have
               of
               very
               compounded
               ones
               ;
               and
               briefly
               to
               propose
               the
               main
               grounds
               ,
               on
               which
               I
               ascrib'd
               those
               advantages
               to
               such
               Remedies
               .
               But
               tho'
               the
               better
               to
               keep
               this
               writing
               from
               being
               prolix
               ,
               I
               design'd
               that
               it
               should
               consist
               chiefly
               of
               such
               particulars
               ,
               as
               I
               could
               best
               spare
               from
               other
               Papers
               ;
               And
               tho'
               for
               that
               reason
               I
               have
               purposely
               omitted
               many
               parable
               ,
               and
               other
               but
               little
               Compounded
               or
               Elaborate
               Medicines
               :
               Yet
               I
               now
               perceive
               that
               ,
               so
               many
               new
               particulars
               having
               offer'd
               themselves
               on
               several
               occasions
               ,
               whilst
               I
               was
               writing
               ,
               my
               Pen
               has
               slipt
               into
               the
               mention
               of
               many
               more
               Receipts
               ,
               and
               Historical
               passages
               ,
               than
               were
               at
               first
               intended
               .
               But
               believing
               the
               subject
               to
               be
               very
               useful
               ,
               and
               not
               despairing
               but
               that
               the
               things
               deliver'd
               on
               it
               may
               not
               
               be
               altogether
               useless
               ;
               I
               dare
               hope
               you
               will
               pardon
               such
               faults
               ,
               as
               only
               my
               desire
               of
               making
               the
               Parts
               of
               this
               small
               writing
               ,
               rather
               serviceable
               than
               Methodical
               or
               well
               proportion'd
               ,
               drew
               me
               unawares
               into
               .
               But
               whatever
               were
               the
               cause
               of
               my
               Prolixity
               ,
               the
               bulk
               which
               I
               see
               this
               Paper
               has
               already
               swell'd
               to
               ,
               admonishes
               me
               ,
               that
               I
               ought
               to
               put
               a
               speedy
               period
               to
               it
               ,
               without
               spending
               time
               solicitously
               to
               declare
               in
               what
               sense
               I
               commend
               the
               Medicines
               deliver'd
               in
               this
               Invitation
               ,
               For
               by
               recalling
               to
               mind
               ,
               what
               I
               have
               formerly
               wrote
               (
               in
               a
               Treatise
               you
               have
               been
               pleas'd
               to
               peruse
               *
               )
               about
               the
               Limitations
               ,
               with
               which
               I
               would
               have
               the
               praises
               I
               give
               of
               Tome
               Remedys
               understood
               ,
               and
               the
               cautions
               with
               which
               I
               would
               have
               them
               administred
               ;
               you
               will
               easily
               be
               perswaded
               ,
               that
               looking
               upon
               them
               but
               as
               fit
               Tools
               in
               a
               skilful
               Workmans
               Hands
               ,
               I
               do
               not
               pretend
               that
               any
               of
               
               them
               should
               do
               the
               Offices
               both
               of
               Physick
               and
               Physician
               too
               :
               and
               that
               I
               propose
               not
               the
               Medicines
               mention'd
               in
               this
               short
               Paper
               ,
               as
               sure
               Specificks
               ,
               but
               as
               instances
               that
               there
               are
               Remedies
               ,
               which
               notwithstanding
               their
               being
               but
               simple
               ones
               ,
               may
               be
               very
               good
               ones
               .
            
             
               
                 
                   I
                   am
                   Sir
                   your
                   most
                
                 &c.
                 R.
                 B.
                 
              
            
             
               FINIS
               .
            
          
        
      
    
     
       
         
         
         
           A
           Catalogue
           of
           late
           Physick
           Books
           sold
           by
           Samuel
           Smith
           ,
           at
           the
           Prince's
           Arms
           ,
           in
           St.
           Pauls
           Churchyard
           .
        
         
           
             Fol.
             
          
           
             BOneti
             Anatomia
             ,
             2.
             
             Vol.
             1680.
             
          
           
             —
             Mercurius
             ,
             1682.
             
          
           
             —
             Medicina
             Septentrionalis
             ,
             1684.
             
          
           
             Bidloo
             Anat.
             humani
             Corporis
             (
             105
             fig.
             illnjirata
             )
             1685.
             
          
           
             Breinii
             Plantarum
             Exoticar
             .
             Cent
             ,
             cum
             Figuris
             ,
             1680.
             
          
           
             Bibliotheca
             Anatom
             .
             cum
             fig.
             2
             vol.
             1685.
             
          
           
             Fabriti
             Hildani
             opera
             cum
             Severino
             ,
             1682.
             
          
           
             HippocratisOpera
             Foetii
             .
          
           
             Hartmanni
             Opera
             omnia
             ,
             1684
             ,
          
           
             Horstii
             Opera
             Med.
             
          
           
             Paracelsi
             Opera
             ,
             2
             vol.
             
          
           
             Dioscoridis
             Opera
             ,
             G.
             Lat.
             
          
           
             Saxoniae
             Opera
             Mid.
             1680.
             
          
           
             Piso
             Hist
             .
             natsiralis
             de
             rebus
             Indiae
             .
          
           
             Schenkii
             Observat
             .
             Med.
             
          
           
             Mentzelii
             Index
             Plant
             ,
             cum
             Figuris
             ,
             1683.
             
          
           
             Lepenii
             Bibliotheca
             Med.
             1683.
             
          
           
             Riverii
             Opera
             ,
             1679.
             
          
           
             Zwelferi
             Pharmacopeia
             ,
             2
             vol.
             
          
           
             Pharmacop
             .
             Angust
             .
             Renovata
             ,
             fine
             Notis
             ,
             1685.
             
          
           
             Wedelii
             Tabulae
             .
          
        
         
           
             Quartoes
             .
          
           
             Alpinus
             Medicina
             AEgypt
             .
          
           
             Borriehius
             de
             ortu
             &
             progressu
             Chimiae
             .
          
           
             
             Borrichii
             Hermetis
             Aegyptiorum
             &
             Chym.
             Sapientia
             .
          
           
             —
             De
             Somno
             &
             somniferis
             .
          
           
             Baubini
             Pinax
             cum
             Prodromo
             .
          
           
             Broeckbuysen
             Oeconomia
             Corporis
             Anim.
             1683.
             
          
           
             Blasii
             Anatomia
             ,
             1681.
             
          
           
             Borellus
             de
             motu
             Animalium
             ,
             2
             vol.
             1685.
             price
             12
             s.
             
          
           
             Bellinus
             At
             Urinis
             &
             Pulsibus
             .
             1685.
             
          
           
             Bohn
             Chymia
             ,
             1685.
             
          
           
             Barbetti
             Opera
             omnia
             .
             1685.
             
          
           
             Blegny
             Zodiacus
             Galen
             .
             Med.
             Chymic
             .
             1682
          
           
             —
             Zodaius
             Gal.
             Med.
             An.
             4
             &
             5.
             1685.
             
          
           
             Bartholini
             Acta
             Medica
             .
             4
             vol.
             
          
           
             Castelli
             Lexicon
             Med.
             1682.
             per
             Bruno
             ,
          
           
             Cardilucil
             Officina
             Sanitatis
             .
          
           
             Clauderi
             Methodus
             Balsamandi
             .
          
           
             —
             De'
             
             Tinctura
             universali
             .
          
           
             Collectanea
             Chymica
             Leydensia
             ,
             1684.
             
          
           
             Clauderi
             Inventum
             cinnabaricum
             ,
             1684.
             
          
           
             Cleyer
             Specimina
             Medicinae
             Sinicae
             ,
             1682.
             
          
           
             Coberi
             Observat
             .
             Med.
             1684.
             
          
           
             Charas
             Pharmacopeia
             Regia
             ,
             1683.
             
          
           
             Charas
             Theriaca
             Andromachi
             ,
             1684.
             
          
           
             —
             Opera
             Omnia
             ,
             1684.
             
          
           
             Diemerbroeck
             Anatomia
             .
          
           
             Davissoni
             Comment
             ,
             in
             Medicinam
             Severini
          
           
             Ettmulleri
             Opera
             Med
             ,
             1685.
             
          
           
             —
             Medicus
             ,
             1685.
             
          
           
             —
             Chimia
             .
          
           
             Dolaei
             Encyclopedia
             Med.
             1684.
             
          
           
             Fernelii
             Opera
             ,
             1683.
             
          
           
             
             Van
             Helmontii
             Opera
             ,
             1682.
             
          
           
             Glisson
             de
             Naturae
             Substantia
             .
          
           
             Hoffmanni
             Praxis
             Med.
             1680.
             
          
           
             Helwigii
             Observationes
             Med.
             1680.
             
          
           
             Hoffmannus
             in
             Schroderum
             .
          
           
             Joel
             Opera
             medica
             .
          
           
             Kyperi
             Anthropologia
             corporis
             humani
             .
          
           
             Konig
             Regnuim
             Animale
             ,
             1682.
             
          
           
             Kunckelii
             Ars
             Vitraria
             .
          
           
             Kirekringii
             Specilegium
             Anatom
             .
          
           
             Licetus
             de
             Monstris
             .
          
           
             Micaelis
             de
             Apoplexia
             ,
             1685.
             
          
           
             Morhoff
             de
             Scypho
             Vitreo
             .
          
           
             Museum
             Hermetic
             .
          
           
             Miscellanea
             Curiosa
             M.
             Physica
             ,
             7
             vol.
             An.
             X
          
           
             —
             Id.
             Decuria
             secunda
             Anni
             Primi
             ,
             1683.
             
          
           
             —
             Dec.
             2.
             
             An.
             2.
             
          
           
             —
             Dec.
             2.
             
             An.
             tertius
             ,
             1685.
             
          
           
             Margravi
             Materia
             Medica
             .
          
           
             —
             Prodromes
             .
          
           
             Pauli
             Quadripartitum
             Botanicum
             .
          
           
             —
             De
             Febribus
             .
          
           
             Plateri
             praxis
             .
          
           
             Pecblinus
             de
             potu
             Theae
             ,
             1684.
             
          
           
             Paulini
             Cynographia
             curiosa
             ,
             1685.
             
          
           
             Peyeri
             Merycologia
             ,
             1685.
             
          
           
             Regii
             Medicina
             .
          
           
             Rolfinchius
             de
             purgantibus
             ,
             1683.
             
          
           
             —
             Ordo
             &
             Methodus
             Med
             ,
             Specialis
          
           
             —
             Concilia
             Med.
             
          
           
             —
             Chimia
             .
          
           
             Sacra
             Eleusinia
             patefacta
             ,
             1684.
             
          
           
             
             Schenckii
             Hist
             .
             de
             humor
             ,
             totius
             corporis
             ,
             1684
          
           
             Salamandrae
             Descriptio
             ,
             1683.
             
          
           
             Sylvii
             Opera
             Med.
             
          
           
             Schrokii
             Pharmacopeia
             ,
             Augustana
             .
          
           
             —
             Hist
             .
             Moschi
             .
          
           
             Sturmii
             Collegium
             Curiosum
             ,
             2
             vol.
             1584.
             
          
           
             Du
             Verney
             de
             auditu
             ,
             in
             fig.
             1685.
             
          
           
             Ang.
             Salae
             Opera
             Med
             ,
             1682.
             
          
           
             Swammerdam
             miraculum
             Naturae
             .
          
           
             Vigerii
             Opera
             med
             ,
          
           
             Versaschae
             de
             Apoplexia
             .
          
           
             Weltheri
             Sylva
             medica
             .
          
           
             Welschii
             Decades
             X.
             med
             .
          
           
             —
             Observat
             .
             &
             curat
             ,
             med
             .
          
           
             —
             Concilia
             ,
             med
             .
          
           
             Wedelii
             Opiologia
             .
          
           
             —
             Physiologia
             Med.
             
          
           
             —
             Pharmacia
             .
          
           
             —
             de
             medicam
             .
             facultatibus
             .
          
           
             —
             de
             medicam
             .
             compositione
             .
          
           
             —
             Am
             aenitates
             Materiae
             Med.
             1684.
             
          
           
             —
             Disputationes
             variae
             ,
             2
             vol.
             
          
           
             Weidenfeld
             de
             usu
             Spir.
             Vini
             Lulliani
             ,
             1684
          
           
             Wepferi
             cicutae
             Aquaticae
             .
          
           
             Zwelferi
             Pharmacop
             .
          
        
         
           
             Octavoes
             .
          
           
             Bartholin
             de
             ductu
             Salivali
             ;
             1685.
             
          
           
             Bruelis
             praxis
             Med.
             
          
           
             Bontekoe
             de
             Febribus
             ,
             1683.
             
          
           
             Tho.
             Bartholini
             Hist
             .
             Anatomica
             .
          
           
             Becke
             de
             Procidentia
             Uteri
             ,
             1683.
             
          
           
             Borelli
             Observat
             .
             Med.
             
          
           
             
             Briggs
             Opthalmo
             Graphin
             .
          
           
             —
             Nova
             Visionis
             Theoria
             ,
          
           
             Barthol
             .
             Anatomia
             .
          
           
             Beck
             .
             Experimenta
             ,
             1684.
             
          
           
             Beckeri
             Physica
             subterranea
             cum
             supplemento
             ,
             1681.
             
          
           
             Brunneri
             Experimenta
             nova
             circa
             Pancreas
             ,
             1682.
             
          
           
             Charleton
             de
             Causis
             Catumor
             ,
             &c.
             
             1685.
             
          
           
             Ent
             contra
             Parisanum
             ,
             de
             circ
             .
             Sang.
             1685.
             
          
           
             —
             Contra
             Thruston
             de
             Respiat
             .
             1685.
             
          
           
             Camerarii
             Sylloges
             memorabilium
             Me.
             2
             vol.
             1683.
             
          
           
             Deckeri
             Exercitationis
             Med
             pract
             .
          
           
             Dodonaei
             Praxis
             Medica
             .
          
           
             Franchimont
             Lithotomia
             Med.
             1683.
             
          
           
             Franciscus
             de
             Venae
             Sectione
             .
             1685.
             
          
           
             Felicis
             de
             Ovis
             cont
             .
             Malpighi
             ,
             1684.
             
          
           
             Funerwalfi
             Anatomia
             .
          
           
             Gockelii
             Concilia
             &
             observat
             .
             Med
             1683.
             
          
           
             De
             Graaf
             Opera
             .
          
           
             Grulichius
             de
             Hydrope
             ,
             1681.
             
          
           
             —
             De
             Bile
             ,
             1682.
             
          
           
             Grimm
             Compend
             .
             Med.
             Chym.
             1684.
             
          
           
             Gieswin
             Hodegus
             ,
             med
             .
          
           
             Guiberti
             Opera
             Med.
             
          
           
             Hartmanni
             Praxis
             Chymiatrica
             ,
             1682.
             
          
           
             Heide
             Anatome
             mytuli
             &
             observat
             .
             Med.
             1684.
             
          
           
             Hippocratis
             Opera
             ,
             2
             vol.
             
          
           
             Juncken
             Chymia
             Experiment
             alis
             ,
             1681.
             
          
           
             —
             Medicus
             praesenti
             Seculo
             Accom
             .
             1682.
             
          
           
             
             Inventa
             nova
             Antiqua
             Med.
             1684.
             
          
           
             Le
             Mort
             Pharmacia
             &
             Chimia
             ,
             1684.
             
          
           
             Lossii
             Concil
             .
             Med.
             1684.
             
          
           
             Lister
             de
             Fontibus
             Med.
             Angliae
             .
          
           
             —
             De
             Insectis
             ,
             1685.
             
          
           
             —
             Appendix
             ad
             Hist
             .
             Animal
             .
             Angl.
             1685.
             
          
           
             Liseri
             Culter
             Anatomicus
             :
          
           
             Maachetti
             Anatomi
          
           
             Meekren
             Observat
             .
             Med.
             Chyrur
             .
             1682
             :
          
           
             Merett
             Pinax
             :
          
           
             Oeconomia
             Animalis
             ,
             1685.
             
          
           
             Plateri
             Observat
             .
             Med.
             
          
           
             Peonis
             &
             Pythagor
             .
             Exercit.
             Anat.
             &
             Med.
             1682
             :
          
           
             Plot
             de
             Origine
             Fontium
             ,
             1685.
             
          
           
             Rulandip
             de
             Phlebotomia
             .
          
           
             Riverii
             Institutiones
             :
          
           
             —
             Praxis
             ,
             2
             vol.
             
          
           
             —
             Observat
             .
          
           
             Rulandi
             Curationes
             Empericae
             ,
             1680.
             
          
           
             Sydenhami
             Opera
             Universa
             Londini
             ,
             1685.
             
          
           
             Sraussii
             Isagoge
             Physica
             ,
             1684.
             
          
           
             Schroderi
             Pharmacopeia
             :
          
           
             Sacchius
             iris
             Febrilis
             ,
             1684.
             
          
           
             —
             Methodus
             Curandi
             Febris
             ,
             1685.
             
          
           
             Sculteti
             Chyrurgia
             cum
             Append.
             
          
           
             Sthal
             Aetiologia
             Phys
             .
             Chym.
             1683.
             
          
           
             Tilingii
             Lilium
             Curiosum
             ,
             1683
             :
          
           
             Prodromus
             ,
             med
             .
          
           
             —
             De
             Laudano
             opiato
             .
          
           
             —
             De
             Febribus
             .
          
           
             Theatrum
             Chymicum
             ,
             6
             vol.
             
          
           
             
             Tulpii
             observat
             .
             med
             .
             1685.
             
          
           
             Versaschae
             Observat
             .
             med
             .
          
           
             Welsch
             rationale
             Vulnerum
             Lethalium
             ,
             1685.
             
          
           
             Wepferi
             de
             Apoplexia
             :
          
           
             Witten
             memoria
             medicor
             .
          
           
             Weberi
             Anchora
             Saucitor
             .
          
           
             Zypaei
             Fundamentu
             med
             .
             1683
             :
          
        
         
           
             Twelves
             .
          
           
             Bayle
             Tract
             .
             de
             Apoplexia
             .
          
           
             —
             Dissertationes
             Physicae
             .
          
           
             —
             Dissertationes
             Medicae
             .
          
           
             —
             Problemata
             Physica
             Med.
             
          
           
             Blondel
             Thermarum
             Aquis
             granen
             .
             &
             porcet
             .
             descript
             .
             1685.
             
          
           
             Barbetti
             Chyrurgia
             :
          
           
             —
             Praxis
             cum
             notis
             Deckerii
             :
          
           
             Broen
             de
             Duplici
             Bile
             Veterum
             ,
             1685.
             
          
           
             Barthol
             .
             De
             Ovariis
             :
          
           
             —
             De
             Unicornu
             :
          
           
             —
             De
             Pulmenum
             substantia
             :
          
           
             Beughen
             Bibliographia
             Med.
             &
             Physica
             ,
             1682
             :
          
           
             Beguini
             Tyrocinium
             Chymicum
             :
          
           
             Comelini
             Catalogus
             Plantarum
             ,
             1682
             :
          
           
             Closs
             .
             de
             Aquis
             min.
             &
             mixtionibus
             ,
             1685.
             
          
           
             Drelincurt
             Praeludium
             Anat.
             
          
           
             —
             Experimenta
             Anat.
             1684.
             
          
           
             —
             De
             Foeminarum
             Ovis
             .
          
           
             —
             De
             Conceptione
             Advers
             .
             1685.
             
          
           
             —
             De
             Hum
             ,
             foetus
             membranis
             .
             P
             685.
             
          
           
             Guiuri
             Arcanum
             Acidular
             .
             1682.
             
          
           
             Glissoni
             Opuscula
             ,
             3
             vol.
             
          
           
             
             Van
             Helmont
             .
             Fundamenta
             Med.
             1681
             :
          
           
             Hoffmanus
             de
             usu
             Lienis
             ,
             &c.
             
             1682
             :
          
           
             Harvey
             de
             Gener.
             Animal
             .
          
           
             —
             De
             motu
             cordis
             :
          
           
             Hoffman
             de
             Cinnabari
             Antimonii
             ,
             1685.
             
          
           
             Ab
             Heer
             Fons
             Spadanus
             &
             Observ
             .
             Med.
             1685.
             
          
           
             Kirchim
             de
             Peste
             ,
             1681.
             
          
           
             Kirckring
             .
             in
             BasilValent
             .
             currum
             Triumph
             .
          
           
             Kunckelii
             Observat
             .
             Chymiae
             ,
             1681
             :
          
           
             Le
             Mort
             Compendium
             Chymicum
             ,
             1862.
             
          
           
             Muralti
             Vade
             mecum
             Anat.
             1682.
             
          
           
             Mysteria
             Physico-Medica
             ,
             1681.
             
          
           
             Maurocordatus
             de
             motu
             Pulmonum
             ,
             1682.
             
          
           
             Macasii
             Promptuarium
             Materiae
             Med.
             
          
           
             Matthaei
             Experimenta
             Chymica
             ,
             1683.
             
          
           
             Muis
             Praxis
             Chyrurgica
             duabus
             partibus
             ,
             1684.
             
          
           
             —
             Decus
             quinta
             ,
             1685.
             
          
           
             Morelli
             Methodus
             perscribendi
             formulas
             .
             Remedior
             .
          
           
             Primerose
             ars
             Pharmae
             .
          
           
             Pecket
             Anatomia
             .
          
           
             Redus
             de
             Insectis
             .
          
           
             Reidlini
             Observ
             .
             med
             .
          
           
             Rivinus
             de
             peste
             lipsiensi
             ,
             1680.
             
          
           
             Riverii
             Arcana
             .
          
           
             St.
             Romani
             Physica
             ,
             1684.
             
          
           
             Recuell
             de
             Curiositez
             ,
             en
             Medicine
             ,
             1685.
             
          
           
             Smitzii
             Compend
             .
             med
             .
             1682.
             
          
           
             Stockhameri
             Micocosmographia
             .
          
           
             Severi
             in
             Synopsis
             Chyrurgio
             .
          
           
             
             Schraderi
             Observationes
             ,
             med
             .
          
           
             Schola
             Salernitana
             .
          
           
             Sponii
             Aphorismi
             Hippoc.
             1684.
             
          
           
             Swalve
             Quaerelae
             Ventriculi
             .
          
           
             —
             Alcali
             &
             Acidum
             .
          
           
             Tilingius
             de
             Renum
             structura
             ,
          
           
             Verlae
             Anat.
             Oculi
             .
          
           
             Vigani
             Medulla
             Chymiae
             .
          
           
             Du
             Verney
             traite
             de
             L'organe
             de
             L'ouvie
             ,
             1683.
             
          
           
             Tencke
             Instrumenta
             curat
             .
             morb
             ,
             1683.
             
          
           
             Wedelii
             Theoremata
             Med.
             
          
           
             —
             De
             Sale
             Volat.
             Plantarum
             .
          
        
      
       
         
           Advertisement
           .
        
         
           THat
           these
           afore
           mentioned
           Books
           in
           Physick
           and
           Chymistry
           ,
           with
           many
           other
           Forreign
           Books
           ,
           are
           sold
           by
           
             Samuel
             Smith
          
           ,
           at
           the
           
             Prince's
             Arms
          
           in
           St.
           
             Pauls
             Church
             yard
          
           ;
           and
           that
           he
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           himself
           with
           much
           variety
           of
           new
           Books
           in
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           ,
           from
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           to
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           from
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           Mart
           ;
           and
           likewise
           he
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           here
           ,
           from
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           ,
           if
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           had
           ,
           beyond
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             Books
             Printed
             for
             ,
             and
             sold
             by
             Samuel
             Smith
             .
          
        
         
           THe
           Philosophical
           Transactions
           published
           by
           the
           Royal
           Society
           Monthly
           ,
           beginning
           January
           1683
           :
        
         
           
             Jo.
             Goedartius
             de
             Insectis
             in
             methodum
             redactus
             cum
             Notularum
             Additions
             Opera
             M.
             Lister
             ,
             item
             Appendicis
             ad
             Hist
             .
             Animalium
             Angliae
             ,
             cum
          
           21
           
             Figuris
             Aeneis
             illustrata
          
           ,
           1685.
           
        
         
           Enquiry
           after
           Happiness
           by
           the
           Author
           of
           
             Practical
             Christianity
          
           ,
           1685.
           
        
         
           The
           Duty
           of
           Servants
           ,
           &c.
           by
           the
           same
           Author
           ,
           1685.
           
        
         
           Boyl's
           Memoirs
           for
           the
           Nat.
           History
           of
           Human
           Blood
           ,
           especially
           the
           Spirit
           of
           that
           Liquor
           ,
           1684.
           
           Price
           2
           s.
           
        
         
           —
           Experiments
           and
           Considerations
           about
           the
           Porosity
           of
           Bodys
           ,
           in
           two
           Essays
           ,
           1684
           ,
           Price
           1
           s.
           6
           d.
           
        
         
           History
           of
           Mineral
           Waters
           ,
           1685.
           
           Price
           1
           s.
           
        
         
           —
           Of
           the
           Reconcileableness
           of
           Specifick
           Medicines
           to
           the
           Corpuscular
           Philosophy
           ,
           with
           an
           Invitation
           to
           the
           use
           of
           Simple
           Medicines
           .
        
         
           
             Tuta
             ac
             Efficax
             Luis
             Venerea
             ,
             sepe
             absque
             mercurio
             ac
             semper
             absque
             Salvatione
             mercuriali
             curandae
             Methodus
             Authore
          
           D.A.M.D.
           1684.
           
        
         
         
           
             De
             variatione
             ,
             ac
             varietate
             pulsus
             observationes
             ,
             accessit
             ejusdem
             Authors
             nova
             Medicinae
             tum
             Speculativae
             ,
             tum
             practicae
             clavis
             .
             Sive
             Ars
             Explorandi
             medicas
             plantarum
             ac
             corporum
             quorumcumqne
             faultates
             ex
             Solo
             Sapore
             ,
          
           1685.
           
        
         
           
             The
             whole
             Art
             of
             the
             Stage
             ,
             &c.
             
          
           Translated
           out
           of
           French.
           In
           Quarto
           ,
           1684.
           
           Price
           5
           s.
           
        
         
           A
           New
           History
           of
           Ethiopia
           ,
           being
           a
           full
           and
           Accurate
           Description
           of
           the
           Kingdom
           of
           Abessinia
           ,
           vulgarly
           ,
           though
           erroneously
           ,
           called
           the
           Empire
           of
           
             Prester
             John
          
           ,
           in
           four
           Books
           (
           illustrated
           with
           many
           Copper
           Plates
           )
           and
           also
           a
           new
           and
           exact
           Map
           of
           the
           Countrey
           ,
           and
           a
           Preface
           shewing
           the
           usefulness
           of
           this
           History
           ,
           with
           the
           Life
           of
           
             Gregorius
             Abba
             ,
             &c.
          
           
           By
           the
           Learned
           
             Job
             Ludolphus
          
           Counceller
           to
           his
           Imperial
           Majesty
           and
           the
           Dukes
           of
           Saxony
           ,
           and
           Treasurer
           to
           His
           Highness
           ,
           the
           Elector
           Palatine
           .
           In
           Fol.
           1684
           Price
           12
           s.
           
        
         
           
             Guideon's
             Fleece
          
           ,
           or
           a
           Vindication
           of
           the
           Colledge
           of
           Physicians
           ,
           in
           answer
           to
           a
           Book
           intituled
           the
           Conclave
           of
           Physicians
           .
           By
           Dr.
           Harvey
           ,
           in
           Quarto
           ,
           1684.
           
           Pr.
           6.
           di
        
         
           An
           Anatomical
           account
           of
           an
           Elephant
           which
           was
           lately
           Dissected
           in
           
             Dublin
             ,
             June
          
           17
           ,
           in
           the
           year
           1681.
           
           By
           A.
           M.
           Med.
           of
           
             Trinity
             Colledge
          
           near
           Dublin
           ,
           illustrated
           with
           Cuts
           ,
           in
           Quarto
           ,
           1682.
           
           Price
           1.
           
             s.
             Swammerdami
             (
             Johan
             .
             )
             Amst
             ,
          
           M.
           D.
           
             Miraculum
             Naturae
          
           .
           In
           Octavo
           .
        
         
         
           A
           Philosophical
           Account
           of
           the
           hard
           Frost
           ,
           with
           what
           Effects
           it
           may
           probably
           have
           upon
           Human
           Bodies
           ,
           as
           to
           Health
           and
           Sickness
           ,
           in
           Quarto
           .
           2
           d.
           Stitcht
           .
        
         
           The
           true
           method
           of
           curing
           Consumptions
           .
           By
           
             S.
             H.
          
           Med.
           D.
           1683.
           
           Price
           1.
           s.
           
        
         
           A
           Discourse
           about
           Bagnio's
           ,
           and
           
             Mineral
             Baths
          
           ,
           and
           of
           the
           drinking
           of
           
             Spaw
             Water
          
           ,
           with
           an
           Account
           of
           the
           Medicinal
           Vertues
           of
           them
           ,
           and
           also
           shewing
           the
           usefulness
           of
           Sweating
           ,
           Rubbing
           ,
           and
           Bathing
           ,
           and
           the
           great
           benefit
           many
           here
           received
           from
           them
           in
           various
           Distempers
           .
           
             By
             S.
             H.
             Med.
             Doct.
          
           1683.
           
        
         
           Miracles
           ,
           Works
           above
           and
           contrary
           to
           Naturer
           ;
           or
           an
           Answer
           to
           a
           late
           Translation
           out
           of
           
             Spinosa's
             Tractatus
             Theologice-politicus
          
           ,
           Mr.
           
             Hobs
             Leviathan
          
           ,
           &c.
           in
           Quarto
           ,
           1683.
           
           Price
           1.
           s.
           
        
         
           A
           Treatise
           of
           
             Self
             Examination
          
           ,
           in
           order
           to
           the
           worthy
           receiving
           the
           Holy
           Communion
           .
           By
           Monsieur
           
             John
             Claude
          
           Minister
           of
           the
           Reformed
           Church
           at
           Paris
           :
           Translated
           from
           the
           French
           Original
           ,
           in
           Twelves
           ,
           1683.
           
        
         
           
             Protestancy
             to
             be
             Embraced
          
           ;
           or
           a
           new
           and
           infallible
           Method
           to
           reduce
           Romanists
           from
           Popery
           to
           Protestancy
           .
           1683.
           pr.
           1.
           s.
           
        
         
           
             The
             Art
             of
             Divine
             Converse
          
           ,
           being
           a
           New
           Years-Gift
           ,
           directing
           how
           to
           walk
           with
           God
           all
           the
           year
           long
           ,
           in
           
             Twelves
             ,
             pr.
          
           6
           ,
           d.
           
        
         
           The
           Councils
           of
           Wisdom
           ,
           or
           the
           Maxims
           of
           Solomon
           ,
           in
           Twelves
           ,
           1683.
           pr.
           1.
           s.
           
        
         
         
           The
           Ten
           Pleasures
           of
           Marriage
           .
           In
           Twelves
           .
        
         
           The
           
             Dutch
             Rogue
          
           :
           or
           Gusman
           of
           Amsterdam
           ,
           traced
           from
           the
           Cradle
           to
           the
           Gallows
           ,
           1683.
           
           In
           Twelves
           .
        
         
           Dr.
           Smith's
           Sermon
           about
           frequent
           Communion
           ,
           1685.
           
        
         
           Mr.
           Fish's
           Sermon
           on
           the
           9th
           of
           May
           ,
           1684.
           
        
         
           History
           of
           the
           Original
           and
           Progress
           of
           Ecclesiastical
           Revenues
           ,
           by
           the
           Learned
           
             P.
             Simon
          
           ,
           1685.
           
        
         
           
             Contra
             Hist
             .
             Aristeae
             de
             LXX
             Interpretibus
             dissertatio
             ,
             five
             responsio
             ad
             D.
             Isaac
             Vosfium
             de
             Septuaginta
             ,
             &c.
             per
             H.
             Hoday
             A.
             M.
          
           1685.
           
        
         
           
             Epigramatum
             delectus
             ex
             omnibus
             tum
             veteribus
             tum
             recentioribus
             Poetis
             s
             accurate
             decerptus
             ,
             &c.
             cum
             dissertatione
             ,
             de
             ver
             a
             pulchritudine
             &
             adumbrata
             ,
             in
             qua
             ex
             certis
             principiis
             ,
             rejectionis
             at
             Selectionis
             Epigramatum
             Causae
             reduntur
             .
             Adjectae
             sunt
             Elegantes
             Sententiae
             ex
             Antiquis
             Poetis
             parce
             ,
             sed
             severiori
             judicio
             selectae
             .
          
           1685.
           
        
         
           A
           Discourse
           about
           Toleration
           ,
           wherein
           the
           late
           Pleas
           for
           it
           made
           by
           the
           D.
           of
           B.
           and
           the
           nameless
           Author
           of
           the
           Considerations
           concerning
           Toleration
           are
           fully
           answered
           ,
           and
           the
           Popular
           Arguments
           drawn
           from
           the
           Practices
           of
           the
           United
           Netherlands
           stated
           at
           large
           ,
           and
           shown
           to
           be
           weak
           ,
           fallacious
           and
           insufficient
           ;
           in
           Quarto
           ,
           Pr.
           1
           s.
           1685.
           
        
         
           FINIS
           .
        
         
         
         
         
      
       
         Notes, typically marginal, from the original text
         
           Notes for div A29016-e620
           
             Galen
             .
             
               de
               Simpl
               .
               Medicam
               .
               Fac.
            
             Lib.
             11.
             
          
           
             Galen
             .
             
               de
               simpl
               .
               Med.
               Fac.
               lib.
            
             11.
             
          
           
             The
             Essay
             of
             the
             Porosity
             of
             Animal
             Bodies
             .
          
           
             *
             
               Ego
               ab
               anno
            
             1649.
             
               in
               hunc
               diem
               per
               integros
            
             14
             
               annos
               ultra
               mille
               Febricitantes
               sine
               Ven.
               ,
               sectione
               ,
               sine
               Purgatione
               ,
               sine
               Sudoriseris
               ,
               sine
               Diureticis
               ,
               sine
               Alterantibus
               ,
               sine
               Corrobarantibus
               ,
               sine
               Topicis
               ,
               &
               siquid
               praeterea
               unico
               fere
            
             Medicamento
             Praecipitante
             ,
             
               Deo
               inprimis
               benedicente
               ,
               curavi
               :
               non
               considerando
               ,
               an
               Febris
               sit
               Intermittens
               ,
               an
               Continua
               ,
               an
               Tertiana
               vel
               Quartana
               (
               quae
               tamen
               difficilius
               curatur
               quàm
               aliae
               )
               nec
               expectatà
               Coctione
               ,
               nec
               habito
               respectu
               sexûs
               ,
               (
               ne
               p●erperis
               quidem
               exceptis
               )
               aetatis
               ,
               anni
               ,
               temporis
               ,
               vel
               aliarum
               Circumstantiarum
               :
               &
               quidem
               paucorum
               dierum
               spatio
               sine
               Recidiva
               vel
               aliquo
               notabili
               incommodo
               ,
               nisi
               ubi
               aeger
               ipse
               per
               Incontinentiam
               de
               novo
               Paroxysmos
               provocarit
               .
            
             Kergerus
             de
             Fermentatione
             ,
             sect
             .
             3.
             cap.
             3.
             
             Pag.
             mihi
             250.
             
          
           
             N.
             B.
             
          
           
             *
             The
             Paper
             here
             mean't
             is
             the
             Essay
             of
             the
             Porosity
             of
             bodys
             .
          
           
             *
             See
             this
             at
             large
             proved
             by
             the
             Learned
             
               Diemerbro●●k
               de
               Peste
               ,
               lib.
               2.
               cap.
               11.
               in
               Annotat.
               
            
          
           
             Galen
             de
             Simp.
             Med.
             facultatib
             .
             Lib.
             ●ono
             .
             Tit.
             de
             Lapid
             .
          
           
             Nic.
             Monard
             
               Simpl.
               Med.
               Hist
               .
               cap.
            
             36.
             p.
             329.
             
          
           
             *
             Untzer
             .
             
               de
               Nephrit
               .
               Lib.
            
             1.
             cap.
             24.
             
          
        
         
           Notes for div A29016-e5940
           
             
               Galen
               .
               de
               Con.
               p.
               Sec.
               Gen.
               lib.
            
             1.
             
          
           
             The
             Vsefulness
             of
             Exp.
             Philosophy
             .
          
           
             Galen
             .
             de
             Simpl.
             Med.
             Facult
             .
             lib.
             ix
             .
             Tiul
             .
             de
             Terra
             Samia
             .
          
           
             See
             Nicol.
             Monard
             Simpl
             .
             Med.
             Histor
             .
             Cap.
             36.
             
             P.
             m.
             329.
             
          
           
             *
             See
             the
             Appendix
             to
             the
             I
             Section
             of
             the
             II
             Part
             of
             the
             usefulness
             of
             Exper.
             Philosophy
             .
             p.
             389-390
             And
             of
             the
             2d
             .
             Edition
             .