id sid tid token lemma pos 50458 1 1 THE the DT 50458 1 2 TOXINS toxin NNS 50458 1 3 AND and CC 50458 1 4 VENOMS venoms NN 50458 1 5 AND and CC 50458 1 6 THEIR their NN 50458 1 7 ANTIBODIES antibody NNS 50458 1 8 BY by IN 50458 1 9 EM em NN 50458 1 10 . . . 50458 2 1 POZZI POZZI NNP 50458 2 2 - - HYPH 50458 2 3 ESCOT ESCOT NNP 50458 2 4 AUTHORIZED AUTHORIZED NNP 50458 2 5 TRANSLATION translation NN 50458 2 6 BY by IN 50458 2 7 ALFRED ALFRED NNP 50458 2 8 I. I. NNP 50458 2 9 COHN COHN NNP 50458 2 10 , , , 50458 2 11 PHAR PHAR NNP 50458 2 12 . . . 50458 3 1 D. D. NNP 50458 3 2 _ _ NNP 50458 3 3 FIRST FIRST NNP 50458 3 4 EDITION EDITION NNP 50458 3 5 _ _ NNP 50458 3 6 FIRST FIRST NNP 50458 3 7 THOUSAND thousand CD 50458 3 8 NEW NEW NNP 50458 3 9 YORK YORK NNP 50458 3 10 JOHN JOHN NNP 50458 3 11 WILEY WILEY NNP 50458 3 12 & & CC 50458 3 13 SONS SONS NNP 50458 3 14 LONDON LONDON NNP 50458 3 15 : : : 50458 3 16 CHAPMAN CHAPMAN NNP 50458 3 17 & & CC 50458 3 18 HALL HALL NNP 50458 3 19 , , , 50458 3 20 LIMITED LIMITED NNP 50458 3 21 1906 1906 CD 50458 3 22 Copyright copyright NN 50458 3 23 , , , 50458 3 24 1906 1906 CD 50458 3 25 BY by IN 50458 3 26 ALFRED ALFRED NNP 50458 3 27 I. I. NNP 50458 3 28 COHN COHN NNP 50458 3 29 ROBERT ROBERT NNP 50458 3 30 DRUMMOND DRUMMOND NNS 50458 3 31 , , , 50458 3 32 PRINTER PRINTER NNP 50458 3 33 , , , 50458 3 34 NEW NEW NNP 50458 3 35 YORK YORK NNP 50458 3 36 INTRODUCTION introduction NN 50458 3 37 . . . 50458 4 1 Our -PRON- PRP$ 50458 4 2 knowledge knowledge NN 50458 4 3 of of IN 50458 4 4 the the DT 50458 4 5 toxins toxin NNS 50458 4 6 is be VBZ 50458 4 7 of of IN 50458 4 8 quite quite RB 50458 4 9 recent recent JJ 50458 4 10 date date NN 50458 4 11 . . . 50458 5 1 It -PRON- PRP 50458 5 2 is be VBZ 50458 5 3 hardly hardly RB 50458 5 4 twenty twenty CD 50458 5 5 years year NNS 50458 5 6 since since IN 50458 5 7 we -PRON- PRP 50458 5 8 began begin VBD 50458 5 9 to to TO 50458 5 10 acquire acquire VB 50458 5 11 a a DT 50458 5 12 knowledge knowledge NN 50458 5 13 of of IN 50458 5 14 the the DT 50458 5 15 facts fact NNS 50458 5 16 that that WDT 50458 5 17 are be VBP 50458 5 18 detailed detail VBN 50458 5 19 in in IN 50458 5 20 this this DT 50458 5 21 volume volume NN 50458 5 22 , , , 50458 5 23 and and CC 50458 5 24 to to TO 50458 5 25 which which WDT 50458 5 26 modern modern JJ 50458 5 27 medicine medicine NN 50458 5 28 owes owe VBZ 50458 5 29 its -PRON- PRP$ 50458 5 30 most most RBS 50458 5 31 recent recent JJ 50458 5 32 and and CC 50458 5 33 marvelous marvelous JJ 50458 5 34 progress progress NN 50458 5 35 , , , 50458 5 36 particularly particularly RB 50458 5 37 in in IN 50458 5 38 serotherapy serotherapy NN 50458 5 39 . . . 50458 6 1 In in IN 50458 6 2 this this DT 50458 6 3 volume volume NN 50458 6 4 we -PRON- PRP 50458 6 5 have have VBP 50458 6 6 studied study VBN 50458 6 7 , , , 50458 6 8 besides besides IN 50458 6 9 the the DT 50458 6 10 true true JJ 50458 6 11 toxins toxin NNS 50458 6 12 -- -- : 50458 6 13 substances substance NNS 50458 6 14 of of IN 50458 6 15 cellular cellular JJ 50458 6 16 origin origin NN 50458 6 17 and and CC 50458 6 18 of of IN 50458 6 19 albuminoid albuminoid NN 50458 6 20 nature nature NN 50458 6 21 and and CC 50458 6 22 unknown unknown JJ 50458 6 23 composition composition NN 50458 6 24 -- -- : 50458 6 25 other other JJ 50458 6 26 toxic toxic JJ 50458 6 27 substances substance NNS 50458 6 28 , , , 50458 6 29 the the DT 50458 6 30 nitrogenized nitrogenized JJ 50458 6 31 alkaloidal alkaloidal NN 50458 6 32 bases basis NNS 50458 6 33 introduced introduce VBN 50458 6 34 into into IN 50458 6 35 science science NN 50458 6 36 through through IN 50458 6 37 the the DT 50458 6 38 researches research NNS 50458 6 39 of of IN 50458 6 40 Selmi Selmi NNP 50458 6 41 , , , 50458 6 42 Armand Armand NNP 50458 6 43 Gautier Gautier NNP 50458 6 44 , , , 50458 6 45 and and CC 50458 6 46 von von NNP 50458 6 47 Behring Behring NNP 50458 6 48 , , , 50458 6 49 and and CC 50458 6 50 which which WDT 50458 6 51 are be VBP 50458 6 52 highly highly RB 50458 6 53 hydrogenized hydrogenize VBN 50458 6 54 nitrogenous nitrogenous JJ 50458 6 55 crystallizable crystallizable JJ 50458 6 56 principles principle NNS 50458 6 57 of of IN 50458 6 58 definite definite JJ 50458 6 59 chemical chemical JJ 50458 6 60 composition composition NN 50458 6 61 -- -- : 50458 6 62 the the DT 50458 6 63 products product NNS 50458 6 64 of of IN 50458 6 65 the the DT 50458 6 66 more more RBR 50458 6 67 or or CC 50458 6 68 less less RBR 50458 6 69 advanced advanced JJ 50458 6 70 breaking break VBG 50458 6 71 down down RP 50458 6 72 of of IN 50458 6 73 albuminoids albuminoid NNS 50458 6 74 . . . 50458 7 1 Although although IN 50458 7 2 these these DT 50458 7 3 principles principle NNS 50458 7 4 differ differ VBP 50458 7 5 widely widely RB 50458 7 6 , , , 50458 7 7 by by IN 50458 7 8 reason reason NN 50458 7 9 of of IN 50458 7 10 their -PRON- PRP$ 50458 7 11 physiological physiological JJ 50458 7 12 properties property NNS 50458 7 13 as as IN 50458 7 14 a a DT 50458 7 15 whole whole NN 50458 7 16 , , , 50458 7 17 from from IN 50458 7 18 the the DT 50458 7 19 toxic toxic JJ 50458 7 20 albuminoids albuminoid NNS 50458 7 21 , , , 50458 7 22 or or CC 50458 7 23 true true JJ 50458 7 24 toxins toxin NNS 50458 7 25 , , , 50458 7 26 it -PRON- PRP 50458 7 27 appears appear VBZ 50458 7 28 proper proper JJ 50458 7 29 to to TO 50458 7 30 consider consider VB 50458 7 31 them -PRON- PRP 50458 7 32 as as IN 50458 7 33 products product NNS 50458 7 34 of of IN 50458 7 35 the the DT 50458 7 36 advanced advanced JJ 50458 7 37 decomposition decomposition NN 50458 7 38 of of IN 50458 7 39 these these DT 50458 7 40 toxins toxin NNS 50458 7 41 -- -- : 50458 7 42 and and CC 50458 7 43 in in IN 50458 7 44 this this DT 50458 7 45 respect respect NN 50458 7 46 their -PRON- PRP$ 50458 7 47 study study NN 50458 7 48 becomes become VBZ 50458 7 49 imperative imperative JJ 50458 7 50 , , , 50458 7 51 the the DT 50458 7 52 more more RBR 50458 7 53 so so RB 50458 7 54 as as IN 50458 7 55 they -PRON- PRP 50458 7 56 are be VBP 50458 7 57 very very RB 50458 7 58 frequently frequently RB 50458 7 59 encountered encounter VBN 50458 7 60 together together RB 50458 7 61 with with IN 50458 7 62 the the DT 50458 7 63 toxins toxin NNS 50458 7 64 , , , 50458 7 65 particularly particularly RB 50458 7 66 in in IN 50458 7 67 serpent serpent NN 50458 7 68 - - HYPH 50458 7 69 venoms venom NNS 50458 7 70 , , , 50458 7 71 where where WRB 50458 7 72 their -PRON- PRP$ 50458 7 73 action action NN 50458 7 74 is be VBZ 50458 7 75 exerted exert VBN 50458 7 76 in in IN 50458 7 77 addition addition NN 50458 7 78 to to IN 50458 7 79 that that DT 50458 7 80 of of IN 50458 7 81 the the DT 50458 7 82 true true JJ 50458 7 83 toxins toxin NNS 50458 7 84 . . . 50458 8 1 In in IN 50458 8 2 the the DT 50458 8 3 first first JJ 50458 8 4 volume volume NN 50458 8 5 of of IN 50458 8 6 this this DT 50458 8 7 collection collection NN 50458 8 8 we -PRON- PRP 50458 8 9 dwelt dwell VBD 50458 8 10 on on IN 50458 8 11 the the DT 50458 8 12 essentially essentially RB 50458 8 13 reducing reduce VBG 50458 8 14 nature nature NN 50458 8 15 of of IN 50458 8 16 the the DT 50458 8 17 cellular cellular JJ 50458 8 18 functionation functionation NN 50458 8 19 . . . 50458 9 1 To to IN 50458 9 2 this this DT 50458 9 3 functionation functionation NN 50458 9 4 -- -- : 50458 9 5 causing cause VBG 50458 9 6 the the DT 50458 9 7 splitting splitting NN 50458 9 8 up up RP 50458 9 9 or or CC 50458 9 10 decomposition decomposition NN 50458 9 11 by by IN 50458 9 12 hydrolysis hydrolysis NN 50458 9 13 of of IN 50458 9 14 nitrogenized nitrogenized JJ 50458 9 15 albuminoid albuminoid NN 50458 9 16 foods food NNS 50458 9 17 -- -- : 50458 9 18 is be VBZ 50458 9 19 due due JJ 50458 9 20 the the DT 50458 9 21 formation formation NN 50458 9 22 of of IN 50458 9 23 these these DT 50458 9 24 toxic toxic JJ 50458 9 25 basic basic JJ 50458 9 26 products product NNS 50458 9 27 within within IN 50458 9 28 the the DT 50458 9 29 organism organism NN 50458 9 30 , , , 50458 9 31 whether whether IN 50458 9 32 normally normally RB 50458 9 33 , , , 50458 9 34 or or CC 50458 9 35 because because IN 50458 9 36 of of IN 50458 9 37 certain certain JJ 50458 9 38 pathological pathological JJ 50458 9 39 conditions condition NNS 50458 9 40 . . . 50458 10 1 This this DT 50458 10 2 alone alone RB 50458 10 3 suffices suffice VBZ 50458 10 4 to to TO 50458 10 5 show show VB 50458 10 6 that that IN 50458 10 7 , , , 50458 10 8 during during IN 50458 10 9 physiological physiological JJ 50458 10 10 life life NN 50458 10 11 , , , 50458 10 12 oxygen oxygen NN 50458 10 13 plays play VBZ 50458 10 14 an an DT 50458 10 15 essentially essentially RB 50458 10 16 antitoxic antitoxic VBN 50458 10 17 rôle rôle VBZ 50458 10 18 within within IN 50458 10 19 the the DT 50458 10 20 organism organism NN 50458 10 21 . . . 50458 11 1 It -PRON- PRP 50458 11 2 is be VBZ 50458 11 3 hoped hope VBN 50458 11 4 that that IN 50458 11 5 this this DT 50458 11 6 succinct succinct JJ 50458 11 7 résumé résumé NN 50458 11 8 , , , 50458 11 9 which which WDT 50458 11 10 it -PRON- PRP 50458 11 11 has have VBZ 50458 11 12 been be VBN 50458 11 13 sought seek VBN 50458 11 14 to to TO 50458 11 15 make make VB 50458 11 16 as as RB 50458 11 17 clear clear JJ 50458 11 18 as as IN 50458 11 19 possible possible JJ 50458 11 20 , , , 50458 11 21 will will MD 50458 11 22 be be VB 50458 11 23 of of IN 50458 11 24 service service NN 50458 11 25 to to IN 50458 11 26 those those DT 50458 11 27 who who WP 50458 11 28 , , , 50458 11 29 while while IN 50458 11 30 not not RB 50458 11 31 scientists scientist NNS 50458 11 32 actively actively RB 50458 11 33 engaged engage VBN 50458 11 34 in in IN 50458 11 35 scientific scientific JJ 50458 11 36 progress progress NN 50458 11 37 , , , 50458 11 38 desire desire NN 50458 11 39 to to TO 50458 11 40 be be VB 50458 11 41 abreast abreast JJ 50458 11 42 of of IN 50458 11 43 the the DT 50458 11 44 knowledge knowledge NN 50458 11 45 of of IN 50458 11 46 modern modern JJ 50458 11 47 evolution evolution NN 50458 11 48 , , , 50458 11 49 but but CC 50458 11 50 yet yet RB 50458 11 51 are be VBP 50458 11 52 not not RB 50458 11 53 in in IN 50458 11 54 a a DT 50458 11 55 position position NN 50458 11 56 to to TO 50458 11 57 consult consult VB 50458 11 58 original original JJ 50458 11 59 papers paper NNS 50458 11 60 or or CC 50458 11 61 large large JJ 50458 11 62 treatises treatise NNS 50458 11 63 . . . 50458 12 1 CONTENTS content NNS 50458 12 2 . . . 50458 13 1 PAGE page NN 50458 13 2 INTRODUCTION introduction NN 50458 13 3 iii iii CD 50458 13 4 PART PART VBN 50458 13 5 I. i. NN 50458 14 1 _ _ NNP 50458 14 2 GENERALITIES GENERALITIES NNP 50458 14 3 REGARDING regard VBG 50458 14 4 TOXINS toxin NNS 50458 14 5 AND and CC 50458 14 6 ANTITOXINS antitoxin NNS 50458 14 7 . . . 50458 14 8 _ _ NNP 50458 14 9 CHAPTER CHAPTER NNP 50458 14 10 I. I. NNP 50458 14 11 ALKALOIDAL ALKALOIDAL NNP 50458 14 12 TOXINS toxin NNS 50458 14 13 , , , 50458 14 14 PTOMAINES PTOMAINES NNP 50458 14 15 , , , 50458 14 16 AND and CC 50458 14 17 LEUCOMAINES LEUCOMAINES NNP 50458 14 18 . . . 50458 15 1 Alkaloidal alkaloidal JJ 50458 15 2 products product NNS 50458 15 3 of of IN 50458 15 4 cellular cellular JJ 50458 15 5 life life NN 50458 15 6 1 1 CD 50458 15 7 Ptomaines ptomaine NNS 50458 15 8 4 4 CD 50458 15 9 Physiological physiological JJ 50458 15 10 action action NN 50458 15 11 5 5 CD 50458 15 12 Extraction extraction NN 50458 15 13 5 5 CD 50458 15 14 Classification Classification NNP 50458 15 15 , , , 50458 15 16 etc etc FW 50458 15 17 . . . 50458 16 1 7 7 CD 50458 16 2 Leucomaines leucomaine NNS 50458 16 3 10 10 CD 50458 16 4 Xanthic xanthic NN 50458 16 5 leucomaines leucomaine NNS 50458 16 6 12 12 CD 50458 16 7 Creatinic creatinic JJ 50458 16 8 leucomaines leucomaine NNS 50458 16 9 13 13 CD 50458 16 10 Neurinic Neurinic NNP 50458 16 11 leucomaines leucomaine NNS 50458 16 12 13 13 CD 50458 16 13 Indeterminate indeterminate JJ 50458 16 14 leucomaines leucomaine NNS 50458 16 15 14 14 CD 50458 16 16 CHAPTER chapter NN 50458 16 17 II II NNP 50458 16 18 . . . 50458 17 1 TOXINS toxin NNS 50458 17 2 AND and CC 50458 17 3 ANTITOXINS antitoxin NNS 50458 17 4 . . . 50458 18 1 Toxins toxin NNS 50458 18 2 15 15 CD 50458 18 3 Action action NN 50458 18 4 of of IN 50458 18 5 pathogenic pathogenic JJ 50458 18 6 bacteria bacteria NNS 50458 18 7 16 16 CD 50458 18 8 Action action NN 50458 18 9 of of IN 50458 18 10 toxins toxin NNS 50458 18 11 17 17 CD 50458 18 12 Nature nature NN 50458 18 13 of of IN 50458 18 14 toxins toxin NNS 50458 18 15 18 18 CD 50458 18 16 Origin origin NN 50458 18 17 of of IN 50458 18 18 toxins toxin NNS 50458 18 19 20 20 CD 50458 18 20 Autointoxications Autointoxications NNPS 50458 18 21 21 21 CD 50458 18 22 General general JJ 50458 18 23 mode mode NN 50458 18 24 of of IN 50458 18 25 action action NN 50458 18 26 23 23 CD 50458 18 27 Constitution Constitution NNP 50458 18 28 of of IN 50458 18 29 toxins toxin NNS 50458 18 30 ; ; : 50458 18 31 Ehrlich Ehrlich NNP 50458 18 32 's 's POS 50458 18 33 theory theory NN 50458 18 34 24 24 CD 50458 18 35 Means mean NNS 50458 18 36 of of IN 50458 18 37 defense defense NN 50458 18 38 possessed possess VBN 50458 18 39 by by IN 50458 18 40 the the DT 50458 18 41 organism organism NN 50458 18 42 against against IN 50458 18 43 the the DT 50458 18 44 action action NN 50458 18 45 of of IN 50458 18 46 toxins toxin NNS 50458 18 47 28 28 CD 50458 18 48 Pasteur Pasteur NNP 50458 18 49 's 's POS 50458 18 50 vaccination vaccination NN 50458 18 51 method method NN 50458 18 52 30 30 CD 50458 18 53 Virus Virus NNP 50458 18 54 action action NN 50458 18 55 30 30 CD 50458 18 56 Phagocytosis Phagocytosis NNP 50458 18 57 32 32 CD 50458 18 58 Antitoxins Antitoxins NNP 50458 18 59 33 33 CD 50458 18 60 Mode mode NN 50458 18 61 of of IN 50458 18 62 action action NN 50458 18 63 35 35 CD 50458 18 64 Formation formation NN 50458 18 65 ; ; : 50458 18 66 Ehrlich Ehrlich NNP 50458 18 67 's 's POS 50458 18 68 theory theory NN 50458 18 69 38 38 CD 50458 18 70 Serotherapy serotherapy NN 50458 18 71 41 41 CD 50458 18 72 PART PART VBN 50458 18 73 II ii CD 50458 18 74 . . . 50458 19 1 _ _ NNP 50458 19 2 THE the DT 50458 19 3 TOXINS TOXINS NNP 50458 19 4 PROPER proper NN 50458 19 5 . . . 50458 19 6 _ _ NNP 50458 19 7 CHAPTER CHAPTER NNP 50458 19 8 III III NNP 50458 19 9 . . . 50458 20 1 I. I. NNP 50458 21 1 VEGETABLE VEGETABLE NNP 50458 21 2 AND and CC 50458 21 3 ANIMAL ANIMAL NNP 50458 21 4 TOXINS toxin NNS 50458 21 5 . . . 50458 22 1 42 42 CD 50458 22 2 Abrin Abrin NNP 50458 22 3 42 42 CD 50458 22 4 Ricin Ricin NNPS 50458 22 5 44 44 CD 50458 22 6 Robin Robin NNP 50458 22 7 45 45 CD 50458 22 8 Toxicity Toxicity NNP 50458 22 9 of of IN 50458 22 10 the the DT 50458 22 11 vegetable vegetable NN 50458 22 12 diastases diastasis NNS 50458 22 13 45 45 CD 50458 22 14 II ii CD 50458 22 15 . . . 50458 23 1 TOXINS toxin NNS 50458 23 2 FROM from IN 50458 23 3 MUSHROOMS MUSHROOMS NNP 50458 23 4 46 46 CD 50458 23 5 Phalline Phalline NNP 50458 23 6 48 48 CD 50458 23 7 Symptomatology Symptomatology NNP 50458 23 8 49 49 CD 50458 23 9 Antidiastases Antidiastases NNPS 50458 23 10 51 51 CD 50458 23 11 III iii CD 50458 23 12 . . . 50458 24 1 ANIMAL ANIMAL NNP 50458 24 2 TOXINS toxin NNS 50458 24 3 53 53 CD 50458 24 4 Peptotoxin Peptotoxin NNP 50458 24 5 53 53 CD 50458 24 6 Alimentary Alimentary NNP 50458 24 7 Intoxications Intoxications NNP 50458 24 8 55 55 CD 50458 24 9 Urinary Urinary NNP 50458 24 10 toxins toxin VBZ 50458 24 11 57 57 CD 50458 24 12 Variation variation NN 50458 24 13 of of IN 50458 24 14 urinary urinary JJ 50458 24 15 toxicity toxicity NN 50458 24 16 59 59 CD 50458 24 17 Autointoxications autointoxication NNS 50458 24 18 ( ( -LRB- 50458 24 19 animal animal NN 50458 24 20 ) ) -RRB- 50458 24 21 60 60 CD 50458 24 22 Glandular glandular JJ 50458 24 23 secretions secretion NNS 50458 24 24 62 62 CD 50458 24 25 Suprarenal suprarenal JJ 50458 24 26 capsules capsule NNS 50458 24 27 63 63 CD 50458 24 28 CHAPTER CHAPTER NNP 50458 24 29 IV IV NNP 50458 24 30 . . . 50458 25 1 THE the DT 50458 25 2 MICROBIAL MICROBIAL NNP 50458 25 3 TOXINS toxin NNS 50458 25 4 . . . 50458 26 1 Pyogenic pyogenic JJ 50458 26 2 and and CC 50458 26 3 pyretogenic pyretogenic NN 50458 26 4 properties property NNS 50458 26 5 66 66 CD 50458 26 6 Anthrax anthrax NN 50458 26 7 toxin toxin NN 50458 26 8 67 67 CD 50458 26 9 Tubercular Tubercular NNP 50458 26 10 toxin toxin NN 50458 26 11 69 69 CD 50458 26 12 Diphtheria Diphtheria NNP 50458 26 13 toxin toxin NN 50458 26 14 71 71 CD 50458 26 15 Tetanus Tetanus NNP 50458 26 16 toxin toxin NN 50458 26 17 76 76 CD 50458 26 18 Mallein Mallein NNP 50458 26 19 79 79 CD 50458 26 20 Typhoid Typhoid NNP 50458 26 21 toxin toxin NN 50458 26 22 80 80 CD 50458 26 23 Cholera Cholera NNP 50458 26 24 toxin toxin NN 50458 26 25 82 82 CD 50458 26 26 CHAPTER chapter NN 50458 26 27 V. V. NNP 50458 26 28 THE the DT 50458 26 29 VENOMS VENOMS NNP 50458 26 30 . . . 50458 27 1 General general JJ 50458 27 2 nature nature NN 50458 27 3 of of IN 50458 27 4 venoms venom NNS 50458 27 5 85 85 CD 50458 27 6 Venomous venomous JJ 50458 27 7 serpents serpent NNS 50458 27 8 87 87 CD 50458 27 9 Nature nature NN 50458 27 10 of of IN 50458 27 11 serpent serpent NN 50458 27 12 - - HYPH 50458 27 13 venoms venom NNS 50458 27 14 88 88 CD 50458 27 15 Natural natural JJ 50458 27 16 immunity immunity NN 50458 27 17 towards towards IN 50458 27 18 serpent serpent NN 50458 27 19 - - HYPH 50458 27 20 venoms venom NNS 50458 27 21 90 90 CD 50458 27 22 Artificial artificial JJ 50458 27 23 immunity immunity NN 50458 27 24 towards towards IN 50458 27 25 serpent serpent JJ 50458 27 26 venoms venom NNS 50458 27 27 91 91 CD 50458 27 28 Venoms venom NNS 50458 27 29 of of IN 50458 27 30 batrachians batrachian NNS 50458 27 31 and and CC 50458 27 32 saurians saurians NNPS 50458 27 33 92 92 CD 50458 27 34 Fish fish NN 50458 27 35 - - HYPH 50458 27 36 poisons poison NNS 50458 27 37 95 95 CD 50458 27 38 Poisons poison NNS 50458 27 39 of of IN 50458 27 40 the the DT 50458 27 41 hymenoptera hymenoptera NN 50458 27 42 96 96 CD 50458 27 43 Poisons poison NNS 50458 27 44 of of IN 50458 27 45 scorpions scorpion NNS 50458 27 46 97 97 CD 50458 27 47 Poisonous poisonous JJ 50458 27 48 blood blood NN 50458 27 49 and and CC 50458 27 50 serums serum NNS 50458 27 51 98 98 CD 50458 27 52 Poisonous poisonous JJ 50458 27 53 meats meat NNS 50458 27 54 100 100 CD 50458 27 55 TOXINS toxin NNS 50458 27 56 AND and CC 50458 27 57 VENOMS venoms NN 50458 27 58 . . . 50458 28 1 PART PART NNP 50458 28 2 I. I. NNP 50458 29 1 _ _ NNP 50458 29 2 GENERALITIES GENERALITIES NNP 50458 29 3 REGARDING regard VBG 50458 29 4 TOXINS toxin NNS 50458 29 5 AND and CC 50458 29 6 ANTITOXINS antitoxin NNS 50458 29 7 . . . 50458 29 8 _ _ NNP 50458 29 9 CHAPTER CHAPTER NNP 50458 29 10 I. I. NNP 50458 29 11 ALKALOIDAL ALKALOIDAL NNP 50458 29 12 TOXINS toxin NNS 50458 29 13 , , , 50458 29 14 PTOMAINES PTOMAINES NNP 50458 29 15 AND and CC 50458 29 16 LEUCOMAINES LEUCOMAINES NNP 50458 29 17 . . . 50458 30 1 = = NFP 50458 30 2 Alkaloidal Alkaloidal NNP 50458 30 3 Products Products NNPS 50458 30 4 of of IN 50458 30 5 Cellular Cellular NNP 50458 30 6 Life.= Life.= NNP 50458 30 7 Before before IN 50458 30 8 entering enter VBG 50458 30 9 upon upon IN 50458 30 10 the the DT 50458 30 11 study study NN 50458 30 12 of of IN 50458 30 13 the the DT 50458 30 14 true true JJ 50458 30 15 toxins toxin NNS 50458 30 16 , , , 50458 30 17 which which WDT 50458 30 18 are be VBP 50458 30 19 products product NNS 50458 30 20 of of IN 50458 30 21 an an DT 50458 30 22 alkaloidal alkaloidal JJ 50458 30 23 nature nature NN 50458 30 24 and and CC 50458 30 25 of of IN 50458 30 26 unknown unknown JJ 50458 30 27 composition composition NN 50458 30 28 , , , 50458 30 29 it -PRON- PRP 50458 30 30 is be VBZ 50458 30 31 necessary necessary JJ 50458 30 32 to to TO 50458 30 33 say say VB 50458 30 34 a a DT 50458 30 35 few few JJ 50458 30 36 words word NNS 50458 30 37 regarding regard VBG 50458 30 38 the the DT 50458 30 39 most most RBS 50458 30 40 definite definite NN 50458 30 41 of of IN 50458 30 42 the the DT 50458 30 43 toxic toxic JJ 50458 30 44 alkaloidal alkaloidal NN 50458 30 45 principles principle NNS 50458 30 46 that that WDT 50458 30 47 are be VBP 50458 30 48 frequently frequently RB 50458 30 49 encountered encounter VBN 50458 30 50 under under IN 50458 30 51 various various JJ 50458 30 52 conditions condition NNS 50458 30 53 , , , 50458 30 54 conjointly conjointly RB 50458 30 55 with with IN 50458 30 56 the the DT 50458 30 57 true true JJ 50458 30 58 toxins toxin NNS 50458 30 59 , , , 50458 30 60 particularly particularly RB 50458 30 61 in in IN 50458 30 62 venoms venom NNS 50458 30 63 , , , 50458 30 64 and and CC 50458 30 65 which which WDT 50458 30 66 , , , 50458 30 67 furthermore furthermore RB 50458 30 68 , , , 50458 30 69 are be VBP 50458 30 70 closely closely RB 50458 30 71 allied allied JJ 50458 30 72 to to IN 50458 30 73 these these DT 50458 30 74 albuminoid albuminoid NN 50458 30 75 toxins toxin NNS 50458 30 76 . . . 50458 31 1 These these DT 50458 31 2 principles principle NNS 50458 31 3 are be VBP 50458 31 4 formed form VBN 50458 31 5 in in IN 50458 31 6 essentially essentially RB 50458 31 7 reducing reduce VBG 50458 31 8 media medium NNS 50458 31 9 , , , 50458 31 10 whether whether IN 50458 31 11 it -PRON- PRP 50458 31 12 be be VB 50458 31 13 within within IN 50458 31 14 the the DT 50458 31 15 body body NN 50458 31 16 of of IN 50458 31 17 the the DT 50458 31 18 organism organism NN 50458 31 19 , , , 50458 31 20 and and CC 50458 31 21 by by IN 50458 31 22 the the DT 50458 31 23 simple simple JJ 50458 31 24 exercise exercise NN 50458 31 25 of of IN 50458 31 26 its -PRON- PRP$ 50458 31 27 normal normal JJ 50458 31 28 function function NN 50458 31 29 , , , 50458 31 30 in in IN 50458 31 31 which which WDT 50458 31 32 case case NN 50458 31 33 the the DT 50458 31 34 principles principle NNS 50458 31 35 bear bear VBP 50458 31 36 the the DT 50458 31 37 generic generic JJ 50458 31 38 name name NN 50458 31 39 _ _ NNP 50458 31 40 leucomaines_[1 leucomaines_[1 NNP 50458 31 41 ] ] -RRB- 50458 31 42 ; ; , 50458 31 43 or or CC 50458 31 44 whether whether IN 50458 31 45 due due IN 50458 31 46 to to IN 50458 31 47 the the DT 50458 31 48 action action NN 50458 31 49 of of IN 50458 31 50 anaerobic anaerobic JJ 50458 31 51 microbes microbe NNS 50458 31 52 , , , 50458 31 53 when when WRB 50458 31 54 they -PRON- PRP 50458 31 55 are be VBP 50458 31 56 designated designate VBN 50458 31 57 as as IN 50458 31 58 ptomaines ptomaine NNS 50458 31 59 . . . 50458 32 1 [ [ -LRB- 50458 32 2 2 2 LS 50458 32 3 ] ] -RRB- 50458 32 4 These these DT 50458 32 5 basic basic JJ 50458 32 6 principles principle NNS 50458 32 7 , , , 50458 32 8 which which WDT 50458 32 9 are be VBP 50458 32 10 essentially essentially RB 50458 32 11 the the DT 50458 32 12 products product NNS 50458 32 13 of of IN 50458 32 14 cellular cellular JJ 50458 32 15 secretion secretion NN 50458 32 16 , , , 50458 32 17 are be VBP 50458 32 18 usually usually RB 50458 32 19 toxic toxic JJ 50458 32 20 , , , 50458 32 21 and and CC 50458 32 22 sometimes sometimes RB 50458 32 23 even even RB 50458 32 24 extremely extremely RB 50458 32 25 so so RB 50458 32 26 . . . 50458 33 1 [ [ -LRB- 50458 33 2 1 1 CD 50458 33 3 ] ] -RRB- 50458 33 4 ARMAND ARMAND NNP 50458 33 5 GAUTIER GAUTIER NNP 50458 33 6 : : : 50458 33 7 Sur Sur NNP 50458 33 8 les les FW 50458 33 9 leucomaines leucomaine NNS 50458 33 10 , , , 50458 33 11 nouveaux nouveaux JJ 50458 33 12 alcaloides alcaloide NNS 50458 33 13 , , , 50458 33 14 dérivés dérivés NNP 50458 33 15 de de NNP 50458 33 16 la la NNP 50458 33 17 transformation transformation NNP 50458 33 18 des des FW 50458 33 19 substances substance NNS 50458 33 20 protéiques protéiques NNP 50458 33 21 des des NNP 50458 33 22 tissus tissus NNP 50458 33 23 vivants vivants NNP 50458 33 24 . . . 50458 34 1 _ _ NNP 50458 34 2 Bull Bull NNP 50458 34 3 . . . 50458 35 1 Soc Soc NNP 50458 35 2 . . . 50458 36 1 Chim Chim NNP 50458 36 2 . . . 50458 36 3 _ _ NNP 50458 36 4 , , , 50458 36 5 2e 2e CD 50458 36 6 série série NN 50458 36 7 , , , 50458 36 8 XLIII XLIII NNP 50458 36 9 , , , 50458 36 10 p. p. NN 50458 36 11 158 158 CD 50458 36 12 . . . 50458 37 1 [ [ -LRB- 50458 37 2 2 2 CD 50458 37 3 ] ] -RRB- 50458 37 4 ARMAND ARMAND NNP 50458 37 5 GAUTIER GAUTIER NNP 50458 37 6 : : : 50458 37 7 " " `` 50458 37 8 Communication communication NN 50458 37 9 sur sur FW 50458 37 10 les les FW 50458 37 11 bases basis NNS 50458 37 12 d'origine d'origine NNP 50458 37 13 putréfactive putréfactive NN 50458 37 14 . . . 50458 37 15 " " '' 50458 38 1 _ _ NNP 50458 38 2 Bull Bull NNP 50458 38 3 . . . 50458 39 1 Soc Soc NNP 50458 39 2 . . . 50458 40 1 Chim Chim NNP 50458 40 2 . . . 50458 40 3 _ _ NNP 50458 40 4 ( ( -LRB- 50458 40 5 2 2 CD 50458 40 6 ) ) -RRB- 50458 40 7 , , , 50458 40 8 XXXVII XXXVII NNP 50458 40 9 , , , 50458 40 10 p. p. NN 50458 40 11 305 305 CD 50458 40 12 . . . 50458 41 1 As as IN 50458 41 2 we -PRON- PRP 50458 41 3 shall shall MD 50458 41 4 presently presently RB 50458 41 5 see see VB 50458 41 6 , , , 50458 41 7 ptomaines ptomaine NNS 50458 41 8 are be VBP 50458 41 9 essentially essentially RB 50458 41 10 products product NNS 50458 41 11 formed form VBN 50458 41 12 during during IN 50458 41 13 putrefactive putrefactive JJ 50458 41 14 fermentation fermentation NN 50458 41 15 . . . 50458 42 1 The the DT 50458 42 2 toxic toxic JJ 50458 42 3 properties property NNS 50458 42 4 of of IN 50458 42 5 extracts extract NNS 50458 42 6 from from IN 50458 42 7 the the DT 50458 42 8 cadaveric cadaveric JJ 50458 42 9 fluids fluid NNS 50458 42 10 have have VBP 50458 42 11 long long RB 50458 42 12 been be VBN 50458 42 13 known know VBN 50458 42 14 . . . 50458 43 1 Already already RB 50458 43 2 in in IN 50458 43 3 1838 1838 CD 50458 43 4 Panum[3 Panum[3 NNP 50458 43 5 ] ] -RRB- 50458 43 6 had have VBD 50458 43 7 met meet VBN 50458 43 8 with with IN 50458 43 9 these these DT 50458 43 10 products product NNS 50458 43 11 in in IN 50458 43 12 snake snake NN 50458 43 13 venoms venom NNS 50458 43 14 . . . 50458 44 1 Bergmann Bergmann NNP 50458 44 2 and and CC 50458 44 3 Schmiedberg[4 Schmiedberg[4 NNP 50458 44 4 ] ] -RRB- 50458 44 5 in in IN 50458 44 6 1868 1868 CD 50458 44 7 isolated isolate VBD 50458 44 8 from from IN 50458 44 9 septic septic NN 50458 44 10 pus pus NNP 50458 44 11 a a DT 50458 44 12 toxic toxic JJ 50458 44 13 substance substance NN 50458 44 14 which which WDT 50458 44 15 they -PRON- PRP 50458 44 16 named name VBD 50458 44 17 _ _ NNP 50458 44 18 sepsin sepsin NN 50458 44 19 _ _ NNP 50458 44 20 ; ; : 50458 44 21 and and CC 50458 44 22 almost almost RB 50458 44 23 at at IN 50458 44 24 the the DT 50458 44 25 same same JJ 50458 44 26 time time NN 50458 44 27 Zuelzer Zuelzer NNP 50458 44 28 and and CC 50458 44 29 Sonnenschein[5 Sonnenschein[5 NNP 50458 44 30 ] ] -RRB- 50458 44 31 reported report VBD 50458 44 32 having have VBG 50458 44 33 isolated isolate VBN 50458 44 34 from from IN 50458 44 35 anatomical anatomical JJ 50458 44 36 preparations preparation NNS 50458 44 37 an an DT 50458 44 38 alkaloid alkaloid RB 50458 44 39 possessing possess VBG 50458 44 40 mydriatic mydriatic JJ 50458 44 41 properties property NNS 50458 44 42 . . . 50458 45 1 It -PRON- PRP 50458 45 2 is be VBZ 50458 45 3 , , , 50458 45 4 however however RB 50458 45 5 , , , 50458 45 6 due due JJ 50458 45 7 particularly particularly RB 50458 45 8 to to IN 50458 45 9 the the DT 50458 45 10 researches research NNS 50458 45 11 of of IN 50458 45 12 Selmi Selmi NNP 50458 45 13 and and CC 50458 45 14 Armand Armand NNP 50458 45 15 Gautier Gautier NNP 50458 45 16 that that IN 50458 45 17 we -PRON- PRP 50458 45 18 are be VBP 50458 45 19 now now RB 50458 45 20 so so RB 50458 45 21 well well RB 50458 45 22 informed informed JJ 50458 45 23 regarding regard VBG 50458 45 24 these these DT 50458 45 25 toxic toxic JJ 50458 45 26 principles principle NNS 50458 45 27 . . . 50458 46 1 [ [ -LRB- 50458 46 2 3 3 CD 50458 46 3 ] ] -RRB- 50458 46 4 _ _ NNP 50458 46 5 Virchow Virchow NNP 50458 46 6 Archiv Archiv NNP 50458 46 7 . . . 50458 46 8 _ _ NNP 50458 46 9 , , , 50458 46 10 X X NNP 50458 46 11 , , , 50458 46 12 p. p. NN 50458 46 13 301 301 CD 50458 46 14 . . . 50458 47 1 [ [ -LRB- 50458 47 2 4 4 CD 50458 47 3 ] ] -RRB- 50458 47 4 _ _ NNP 50458 47 5 Medic Medic NNP 50458 47 6 . . . 50458 48 1 Centralblatt Centralblatt NNP 50458 48 2 _ _ NNP 50458 48 3 , , , 50458 48 4 1868 1868 CD 50458 48 5 , , , 50458 48 6 p. p. NN 50458 48 7 497 497 CD 50458 48 8 . . . 50458 49 1 [ [ -LRB- 50458 49 2 5 5 CD 50458 49 3 ] ] -RRB- 50458 49 4 _ _ NNP 50458 49 5 Berlin Berlin NNP 50458 49 6 . . . 50458 50 1 Klin Klin NNP 50458 50 2 . . . 50458 51 1 Woch Woch NNP 50458 51 2 . . . 50458 51 3 _ _ NNP 50458 51 4 , , , 50458 51 5 1869 1869 CD 50458 51 6 , , , 50458 51 7 No no UH 50458 51 8 . . . 50458 52 1 2 2 LS 50458 52 2 . . . 50458 53 1 The the DT 50458 53 2 labors labor NNS 50458 53 3 of of IN 50458 53 4 Armand Armand NNP 50458 53 5 Gautier Gautier NNP 50458 53 6 were be VBD 50458 53 7 first first RB 50458 53 8 published publish VBN 50458 53 9 in in IN 50458 53 10 his -PRON- PRP$ 50458 53 11 _ _ NNP 50458 53 12 Traité Traité NNP 50458 53 13 de de FW 50458 53 14 Chimie Chimie NNP 50458 53 15 Appliquée Appliquée NNP 50458 53 16 à à NNP 50458 53 17 la la NNP 50458 53 18 Physiologie Physiologie NNP 50458 53 19 _ _ NNP 50458 53 20 ; ; : 50458 53 21 those those DT 50458 53 22 of of IN 50458 53 23 Selmi Selmi NNPS 50458 53 24 in in IN 50458 53 25 the the DT 50458 53 26 _ _ NNP 50458 53 27 Actes Actes NNP 50458 53 28 de de NNP 50458 53 29 l'Académie l'Académie NNP 50458 53 30 de de NNP 50458 53 31 Bologne Bologne NNP 50458 53 32 _ _ NNP 50458 53 33 . . . 50458 54 1 At at IN 50458 54 2 first first JJ 50458 54 3 sight sight NN 50458 54 4 , , , 50458 54 5 there there EX 50458 54 6 appears appear VBZ 50458 54 7 to to TO 50458 54 8 be be VB 50458 54 9 a a DT 50458 54 10 great great JJ 50458 54 11 difference difference NN 50458 54 12 between between IN 50458 54 13 these these DT 50458 54 14 alkaloidal alkaloidal NN 50458 54 15 bases basis NNS 50458 54 16 , , , 50458 54 17 the the DT 50458 54 18 ptomaines ptomaine NNS 50458 54 19 and and CC 50458 54 20 leucomaines leucomaine NNS 50458 54 21 , , , 50458 54 22 and and CC 50458 54 23 the the DT 50458 54 24 albuminoid albuminoid NN 50458 54 25 toxins toxin NNS 50458 54 26 proper proper JJ 50458 54 27 . . . 50458 55 1 The the DT 50458 55 2 toxic toxic JJ 50458 55 3 bases basis NNS 50458 55 4 of of IN 50458 55 5 the the DT 50458 55 6 first first JJ 50458 55 7 two two CD 50458 55 8 groups group NNS 50458 55 9 are be VBP 50458 55 10 quite quite RB 50458 55 11 definite definite JJ 50458 55 12 chemical chemical JJ 50458 55 13 products product NNS 50458 55 14 which which WDT 50458 55 15 can can MD 50458 55 16 be be VB 50458 55 17 generally generally RB 50458 55 18 obtained obtain VBN 50458 55 19 quite quite RB 50458 55 20 pure pure JJ 50458 55 21 , , , 50458 55 22 and and CC 50458 55 23 frequently frequently RB 50458 55 24 in in IN 50458 55 25 crystalline crystalline NN 50458 55 26 form form NN 50458 55 27 . . . 50458 56 1 The the DT 50458 56 2 toxins toxin NNS 50458 56 3 proper proper JJ 50458 56 4 , , , 50458 56 5 on on IN 50458 56 6 the the DT 50458 56 7 other other JJ 50458 56 8 hand hand NN 50458 56 9 , , , 50458 56 10 are be VBP 50458 56 11 highly highly RB 50458 56 12 complex complex JJ 50458 56 13 albuminoid albuminoid NN 50458 56 14 substances substance NNS 50458 56 15 which which WDT 50458 56 16 greatly greatly RB 50458 56 17 resemble resemble VBP 50458 56 18 the the DT 50458 56 19 true true JJ 50458 56 20 diastases diastasis NNS 50458 56 21 in in IN 50458 56 22 all all PDT 50458 56 23 their -PRON- PRP$ 50458 56 24 properties property NNS 50458 56 25 . . . 50458 57 1 Nevertheless nevertheless RB 50458 57 2 , , , 50458 57 3 between between IN 50458 57 4 the the DT 50458 57 5 toxic toxic JJ 50458 57 6 alkaloids alkaloid NNS 50458 57 7 , , , 50458 57 8 ptomaines ptomaine NNS 50458 57 9 and and CC 50458 57 10 leucomaines leucomaine NNS 50458 57 11 , , , 50458 57 12 and and CC 50458 57 13 the the DT 50458 57 14 toxic toxic JJ 50458 57 15 albuminoids albuminoid NNS 50458 57 16 , , , 50458 57 17 or or CC 50458 57 18 more more RBR 50458 57 19 properly properly RB 50458 57 20 toxins toxin NNS 50458 57 21 , , , 50458 57 22 there there EX 50458 57 23 exists exist VBZ 50458 57 24 no no DT 50458 57 25 absolutely absolutely RB 50458 57 26 sharp sharp JJ 50458 57 27 line line NN 50458 57 28 of of IN 50458 57 29 demarcation demarcation NN 50458 57 30 , , , 50458 57 31 but but CC 50458 57 32 there there EX 50458 57 33 is be VBZ 50458 57 34 a a DT 50458 57 35 gradual gradual JJ 50458 57 36 passage passage NN 50458 57 37 from from IN 50458 57 38 the the DT 50458 57 39 one one NN 50458 57 40 to to IN 50458 57 41 the the DT 50458 57 42 other other JJ 50458 57 43 by by IN 50458 57 44 every every DT 50458 57 45 intermediary intermediary JJ 50458 57 46 grade grade NN 50458 57 47 , , , 50458 57 48 as as IN 50458 57 49 a a DT 50458 57 50 result result NN 50458 57 51 of of IN 50458 57 52 the the DT 50458 57 53 breaking break VBG 50458 57 54 down down RP 50458 57 55 of of IN 50458 57 56 the the DT 50458 57 57 albuminoid albuminoid NN 50458 57 58 molecule molecule NN 50458 57 59 . . . 50458 58 1 We -PRON- PRP 50458 58 2 shall shall MD 50458 58 3 see see VB 50458 58 4 , , , 50458 58 5 moreover moreover RB 50458 58 6 , , , 50458 58 7 as as IN 50458 58 8 we -PRON- PRP 50458 58 9 proceed proceed VBP 50458 58 10 , , , 50458 58 11 that that IN 50458 58 12 these these DT 50458 58 13 substances substance NNS 50458 58 14 are be VBP 50458 58 15 formed form VBN 50458 58 16 under under IN 50458 58 17 coexistent coexistent NN 50458 58 18 circumstances circumstance NNS 50458 58 19 , , , 50458 58 20 and and CC 50458 58 21 that that IN 50458 58 22 they -PRON- PRP 50458 58 23 are be VBP 50458 58 24 , , , 50458 58 25 hence hence RB 50458 58 26 , , , 50458 58 27 found find VBD 50458 58 28 together together RB 50458 58 29 , , , 50458 58 30 whether whether IN 50458 58 31 it -PRON- PRP 50458 58 32 be be VBP 50458 58 33 in in IN 50458 58 34 virus virus NN 50458 58 35 or or CC 50458 58 36 in in IN 50458 58 37 snake snake NN 50458 58 38 venom venom NN 50458 58 39 . . . 50458 59 1 We -PRON- PRP 50458 59 2 will will MD 50458 59 3 first first RB 50458 59 4 consider consider VB 50458 59 5 the the DT 50458 59 6 ptomaines ptomaine NNS 50458 59 7 , , , 50458 59 8 and and CC 50458 59 9 then then RB 50458 59 10 the the DT 50458 59 11 leucomaines leucomaine NNS 50458 59 12 . . . 50458 60 1 = = NFP 50458 60 2 Ptomaines.= Ptomaines.= NNP 50458 60 3 This this DT 50458 60 4 name name NN 50458 60 5 is be VBZ 50458 60 6 more more RBR 50458 60 7 specially specially RB 50458 60 8 reserved reserved JJ 50458 60 9 to to TO 50458 60 10 designate designate VB 50458 60 11 those those DT 50458 60 12 alkaloidal alkaloidal NN 50458 60 13 substances substance NNS 50458 60 14 , , , 50458 60 15 generally generally RB 50458 60 16 highly highly RB 50458 60 17 hydrogenized hydrogenize VBN 50458 60 18 , , , 50458 60 19 that that WDT 50458 60 20 are be VBP 50458 60 21 formed form VBN 50458 60 22 outside outside IN 50458 60 23 the the DT 50458 60 24 organism organism NN 50458 60 25 , , , 50458 60 26 from from IN 50458 60 27 the the DT 50458 60 28 fermentative fermentative JJ 50458 60 29 action action NN 50458 60 30 of of IN 50458 60 31 anaerobic anaerobic JJ 50458 60 32 microbes microbe NNS 50458 60 33 on on IN 50458 60 34 albuminoid albuminoid NN 50458 60 35 substances substance NNS 50458 60 36 . . . 50458 61 1 These these DT 50458 61 2 bases basis NNS 50458 61 3 are be VBP 50458 61 4 generally generally RB 50458 61 5 volatile volatile JJ 50458 61 6 , , , 50458 61 7 with with IN 50458 61 8 an an DT 50458 61 9 intense intense JJ 50458 61 10 and and CC 50458 61 11 tenacious tenacious JJ 50458 61 12 purulent purulent NN 50458 61 13 odor odor RB 50458 61 14 ; ; : 50458 61 15 often often RB 50458 61 16 , , , 50458 61 17 however however RB 50458 61 18 , , , 50458 61 19 they -PRON- PRP 50458 61 20 possess possess VBP 50458 61 21 a a DT 50458 61 22 floral floral JJ 50458 61 23 odor odor NN 50458 61 24 ( ( -LRB- 50458 61 25 aubépine aubépine NNP 50458 61 26 , , , 50458 61 27 syringa syringa NNP 50458 61 28 ) ) -RRB- 50458 61 29 , , , 50458 61 30 and and CC 50458 61 31 even even RB 50458 61 32 like like IN 50458 61 33 that that DT 50458 61 34 of of IN 50458 61 35 musk musk NN 50458 61 36 . . . 50458 62 1 They -PRON- PRP 50458 62 2 combine combine VBP 50458 62 3 readily readily RB 50458 62 4 with with IN 50458 62 5 acids acid NNS 50458 62 6 and and CC 50458 62 7 with with IN 50458 62 8 the the DT 50458 62 9 chlorides chloride NNS 50458 62 10 of of IN 50458 62 11 the the DT 50458 62 12 heavy heavy JJ 50458 62 13 metals metal NNS 50458 62 14 , , , 50458 62 15 yielding yield VBG 50458 62 16 crystallizable crystallizable JJ 50458 62 17 salts salt NNS 50458 62 18 . . . 50458 63 1 The the DT 50458 63 2 ptomaines ptomaine NNS 50458 63 3 afford afford VBP 50458 63 4 no no DT 50458 63 5 specific specific JJ 50458 63 6 reaction reaction NN 50458 63 7 whereby whereby WRB 50458 63 8 they -PRON- PRP 50458 63 9 may may MD 50458 63 10 be be VB 50458 63 11 readily readily RB 50458 63 12 identified identify VBN 50458 63 13 ; ; : 50458 63 14 and and CC 50458 63 15 their -PRON- PRP$ 50458 63 16 identification identification NN 50458 63 17 is be VBZ 50458 63 18 effected effect VBN 50458 63 19 only only RB 50458 63 20 after after IN 50458 63 21 a a DT 50458 63 22 painstaking painstaking JJ 50458 63 23 analysis analysis NN 50458 63 24 . . . 50458 64 1 We -PRON- PRP 50458 64 2 must must MD 50458 64 3 here here RB 50458 64 4 call call VB 50458 64 5 attention attention NN 50458 64 6 , , , 50458 64 7 however however RB 50458 64 8 , , , 50458 64 9 to to IN 50458 64 10 several several JJ 50458 64 11 of of IN 50458 64 12 their -PRON- PRP$ 50458 64 13 more more RBR 50458 64 14 common common JJ 50458 64 15 properties property NNS 50458 64 16 , , , 50458 64 17 beginning begin VBG 50458 64 18 with with IN 50458 64 19 their -PRON- PRP$ 50458 64 20 basic basic JJ 50458 64 21 character character NN 50458 64 22 , , , 50458 64 23 their -PRON- PRP$ 50458 64 24 oxidizability oxidizability NN 50458 64 25 by by IN 50458 64 26 the the DT 50458 64 27 air air NN 50458 64 28 and and CC 50458 64 29 consequently consequently RB 50458 64 30 their -PRON- PRP$ 50458 64 31 well well RB 50458 64 32 - - HYPH 50458 64 33 defined define VBN 50458 64 34 reducing reduce VBG 50458 64 35 power power NN 50458 64 36 -- -- : 50458 64 37 a a DT 50458 64 38 property property NN 50458 64 39 that that WDT 50458 64 40 led lead VBD 50458 64 41 Selmi Selmi VBN 50458 64 42 to to TO 50458 64 43 propose propose VB 50458 64 44 a a DT 50458 64 45 mixture mixture NN 50458 64 46 of of IN 50458 64 47 ferric ferric JJ 50458 64 48 chloride chloride NN 50458 64 49 and and CC 50458 64 50 potassium potassium NN 50458 64 51 ferricyanide ferricyanide NN 50458 64 52 as as IN 50458 64 53 a a DT 50458 64 54 reagent reagent NN 50458 64 55 for for IN 50458 64 56 their -PRON- PRP$ 50458 64 57 detection detection NN 50458 64 58 . . . 50458 65 1 [ [ -LRB- 50458 65 2 6 6 CD 50458 65 3 ] ] -RRB- 50458 65 4 They -PRON- PRP 50458 65 5 are be VBP 50458 65 6 precipitated precipitate VBN 50458 65 7 by by IN 50458 65 8 all all PDT 50458 65 9 the the DT 50458 65 10 general general JJ 50458 65 11 reagents reagent NNS 50458 65 12 for for IN 50458 65 13 the the DT 50458 65 14 vegetable vegetable NN 50458 65 15 alkaloids alkaloid NNS 50458 65 16 . . . 50458 66 1 Selmi Selmi NNP 50458 66 2 has have VBZ 50458 66 3 given give VBN 50458 66 4 several several JJ 50458 66 5 reactions reaction NNS 50458 66 6 , , , 50458 66 7 such such JJ 50458 66 8 as as IN 50458 66 9 those those DT 50458 66 10 afforded afford VBN 50458 66 11 by by IN 50458 66 12 sulphuric sulphuric JJ 50458 66 13 , , , 50458 66 14 hydrochloric hydrochloric JJ 50458 66 15 , , , 50458 66 16 and and CC 50458 66 17 nitric nitric JJ 50458 66 18 acids acid NNS 50458 66 19 , , , 50458 66 20 which which WDT 50458 66 21 appear appear VBP 50458 66 22 , , , 50458 66 23 however however RB 50458 66 24 , , , 50458 66 25 to to TO 50458 66 26 apply apply VB 50458 66 27 much much RB 50458 66 28 more more JJR 50458 66 29 to to IN 50458 66 30 the the DT 50458 66 31 impurities impurity NNS 50458 66 32 present present JJ 50458 66 33 than than IN 50458 66 34 to to IN 50458 66 35 the the DT 50458 66 36 bases basis NNS 50458 66 37 themselves -PRON- PRP 50458 66 38 . . . 50458 67 1 [ [ -LRB- 50458 67 2 6 6 CD 50458 67 3 ] ] -RRB- 50458 67 4 Sulle Sulle NNP 50458 67 5 ptomaïne ptomaïne NN 50458 67 6 od od NNP 50458 67 7 alcaloïdi alcaloïdi NNP 50458 67 8 cadaverici cadaverici NNP 50458 67 9 . . . 50458 68 1 Bologne bologne VB 50458 68 2 , , , 50458 68 3 CLXXXVII clxxxvii NN 50458 68 4 , , , 50458 68 5 p. p. NN 50458 68 6 11 11 CD 50458 68 7 . . . 50458 69 1 The the DT 50458 69 2 physiological physiological JJ 50458 69 3 action action NN 50458 69 4 of of IN 50458 69 5 these these DT 50458 69 6 bases basis NNS 50458 69 7 varies vary VBZ 50458 69 8 greatly greatly RB 50458 69 9 ; ; : 50458 69 10 in in IN 50458 69 11 some some DT 50458 69 12 the the DT 50458 69 13 action action NN 50458 69 14 is be VBZ 50458 69 15 an an DT 50458 69 16 extremely extremely RB 50458 69 17 toxic toxic JJ 50458 69 18 one one NN 50458 69 19 , , , 50458 69 20 as as IN 50458 69 21 in in IN 50458 69 22 the the DT 50458 69 23 case case NN 50458 69 24 of of IN 50458 69 25 neurine neurine NNP 50458 69 26 and and CC 50458 69 27 muscarine muscarine NNP 50458 69 28 , , , 50458 69 29 which which WDT 50458 69 30 are be VBP 50458 69 31 true true JJ 50458 69 32 ptomaines ptomaine NNS 50458 69 33 ; ; : 50458 69 34 there there EX 50458 69 35 are be VBP 50458 69 36 others other NNS 50458 69 37 , , , 50458 69 38 such such JJ 50458 69 39 as as IN 50458 69 40 cadaverine cadaverine NN 50458 69 41 and and CC 50458 69 42 putrescine putrescine NN 50458 69 43 , , , 50458 69 44 which which WDT 50458 69 45 are be VBP 50458 69 46 quite quite RB 50458 69 47 innocuous innocuous JJ 50458 69 48 . . . 50458 70 1 The the DT 50458 70 2 physiological physiological JJ 50458 70 3 action action NN 50458 70 4 of of IN 50458 70 5 these these DT 50458 70 6 bases basis NNS 50458 70 7 , , , 50458 70 8 like like IN 50458 70 9 that that DT 50458 70 10 of of IN 50458 70 11 the the DT 50458 70 12 true true JJ 50458 70 13 toxins toxin NNS 50458 70 14 , , , 50458 70 15 is be VBZ 50458 70 16 studied study VBN 50458 70 17 by by IN 50458 70 18 making make VBG 50458 70 19 hypodermic hypodermic JJ 50458 70 20 injections injection NNS 50458 70 21 of of IN 50458 70 22 solutions solution NNS 50458 70 23 of of IN 50458 70 24 the the DT 50458 70 25 bases basis NNS 50458 70 26 in in IN 50458 70 27 healthy healthy JJ 50458 70 28 animals animal NNS 50458 70 29 , , , 50458 70 30 such such JJ 50458 70 31 as as IN 50458 70 32 guinea guinea NN 50458 70 33 - - HYPH 50458 70 34 pigs pig NNS 50458 70 35 , , , 50458 70 36 rabbits rabbit NNS 50458 70 37 , , , 50458 70 38 and and CC 50458 70 39 dogs dog NNS 50458 70 40 . . . 50458 71 1 In in IN 50458 71 2 animals animal NNS 50458 71 3 , , , 50458 71 4 the the DT 50458 71 5 principal principal JJ 50458 71 6 phenomena phenomenon NNS 50458 71 7 observed observe VBN 50458 71 8 by by IN 50458 71 9 Selmi Selmi NNS 50458 71 10 to to TO 50458 71 11 follow follow VB 50458 71 12 the the DT 50458 71 13 injection injection NN 50458 71 14 of of IN 50458 71 15 the the DT 50458 71 16 substances substance NNS 50458 71 17 are be VBP 50458 71 18 the the DT 50458 71 19 following follow VBG 50458 71 20 : : : 50458 71 21 At at IN 50458 71 22 first first JJ 50458 71 23 dilatation dilatation NN 50458 71 24 of of IN 50458 71 25 the the DT 50458 71 26 pupil pupil NN 50458 71 27 , , , 50458 71 28 then then RB 50458 71 29 constriction constriction NN 50458 71 30 ; ; , 50458 71 31 tetanic tetanic JJ 50458 71 32 convulsions convulsion NNS 50458 71 33 , , , 50458 71 34 soon soon RB 50458 71 35 followed follow VBN 50458 71 36 by by IN 50458 71 37 muscular muscular JJ 50458 71 38 relaxation relaxation NN 50458 71 39 , , , 50458 71 40 and and CC 50458 71 41 retardation retardation NN 50458 71 42 , , , 50458 71 43 rarely rarely RB 50458 71 44 acceleration acceleration NN 50458 71 45 , , , 50458 71 46 of of IN 50458 71 47 heart heart NN 50458 71 48 - - HYPH 50458 71 49 beat beat VBN 50458 71 50 ; ; , 50458 71 51 absolute absolute JJ 50458 71 52 loss loss NN 50458 71 53 of of IN 50458 71 54 cutaneous cutaneous JJ 50458 71 55 sensibility sensibility NN 50458 71 56 ; ; : 50458 71 57 loss loss NN 50458 71 58 of of IN 50458 71 59 muscular muscular JJ 50458 71 60 contractility contractility NN 50458 71 61 ; ; : 50458 71 62 paralysis paralysis NN 50458 71 63 of of IN 50458 71 64 the the DT 50458 71 65 vasomotors vasomotor NNS 50458 71 66 ; ; : 50458 71 67 greatly greatly RB 50458 71 68 retarded retarded JJ 50458 71 69 respiration respiration NN 50458 71 70 ; ; : 50458 71 71 stupor stupor NN 50458 71 72 , , , 50458 71 73 followed follow VBN 50458 71 74 by by IN 50458 71 75 death death NN 50458 71 76 with with IN 50458 71 77 the the DT 50458 71 78 heart heart NN 50458 71 79 in in IN 50458 71 80 systole systole NNP 50458 71 81 . . . 50458 72 1 It -PRON- PRP 50458 72 2 must must MD 50458 72 3 be be VB 50458 72 4 observed observe VBN 50458 72 5 that that IN 50458 72 6 in in IN 50458 72 7 a a DT 50458 72 8 number number NN 50458 72 9 of of IN 50458 72 10 cases case NNS 50458 72 11 where where WRB 50458 72 12 toxic toxic JJ 50458 72 13 researches research NNS 50458 72 14 had have VBD 50458 72 15 been be VBN 50458 72 16 made make VBN 50458 72 17 in in IN 50458 72 18 the the DT 50458 72 19 past past NN 50458 72 20 , , , 50458 72 21 these these DT 50458 72 22 bases basis NNS 50458 72 23 had have VBD 50458 72 24 been be VBN 50458 72 25 mistaken mistake VBN 50458 72 26 for for IN 50458 72 27 poisons poison NNS 50458 72 28 which which WDT 50458 72 29 were be VBD 50458 72 30 believed believe VBN 50458 72 31 to to TO 50458 72 32 have have VB 50458 72 33 been be VBN 50458 72 34 introduced introduce VBN 50458 72 35 into into IN 50458 72 36 the the DT 50458 72 37 organism organism NN 50458 72 38 with with IN 50458 72 39 criminal criminal JJ 50458 72 40 intent intent NN 50458 72 41 . . . 50458 73 1 No no DT 50458 73 2 one one NN 50458 73 3 will will MD 50458 73 4 ever ever RB 50458 73 5 know know VB 50458 73 6 how how WRB 50458 73 7 many many JJ 50458 73 8 have have VBP 50458 73 9 fallen fall VBN 50458 73 10 victims victim NNS 50458 73 11 in in IN 50458 73 12 the the DT 50458 73 13 past past NN 50458 73 14 to to IN 50458 73 15 ignorance ignorance NN 50458 73 16 regarding regard VBG 50458 73 17 the the DT 50458 73 18 cellular cellular JJ 50458 73 19 mechanism mechanism NN 50458 73 20 ! ! . 50458 74 1 The the DT 50458 74 2 extraction extraction NN 50458 74 3 of of IN 50458 74 4 these these DT 50458 74 5 bases basis NNS 50458 74 6 is be VBZ 50458 74 7 a a DT 50458 74 8 tedious tedious JJ 50458 74 9 and and CC 50458 74 10 difficult difficult JJ 50458 74 11 operation operation NN 50458 74 12 . . . 50458 75 1 The the DT 50458 75 2 materials material NNS 50458 75 3 must must MD 50458 75 4 first first RB 50458 75 5 be be VB 50458 75 6 exhausted exhaust VBN 50458 75 7 with with IN 50458 75 8 water water NN 50458 75 9 slightly slightly RB 50458 75 10 acidulated acidulate VBN 50458 75 11 ; ; : 50458 75 12 then then RB 50458 75 13 , , , 50458 75 14 after after IN 50458 75 15 precipitating precipitate VBG 50458 75 16 the the DT 50458 75 17 albuminoids albuminoid NNS 50458 75 18 by by IN 50458 75 19 boiling boil VBG 50458 75 20 and and CC 50458 75 21 defecating defecate VBG 50458 75 22 by by IN 50458 75 23 adding add VBG 50458 75 24 lead lead NN 50458 75 25 acetate acetate NNP 50458 75 26 , , , 50458 75 27 the the DT 50458 75 28 liquid liquid NN 50458 75 29 is be VBZ 50458 75 30 evaporated evaporate VBN 50458 75 31 to to IN 50458 75 32 one one CD 50458 75 33 - - HYPH 50458 75 34 half half NN 50458 75 35 its -PRON- PRP$ 50458 75 36 volume volume NN 50458 75 37 and and CC 50458 75 38 dialyzed dialyze VBN 50458 75 39 in in IN 50458 75 40 a a DT 50458 75 41 vacuum vacuum NN 50458 75 42 . . . 50458 76 1 [ [ -LRB- 50458 76 2 7 7 CD 50458 76 3 ] ] -RRB- 50458 76 4 [ [ -LRB- 50458 76 5 7 7 CD 50458 76 6 ] ] -RRB- 50458 76 7 ARMAND ARMAND NNP 50458 76 8 GAUTIER GAUTIER NNP 50458 76 9 : : : 50458 76 10 _ _ NNP 50458 76 11 C. C. NNP 50458 77 1 rend rend VB 50458 77 2 . . . 50458 78 1 de de NNP 50458 78 2 l'Académie l'Académie NNP 50458 78 3 des des NNP 50458 78 4 Sciences Sciences NNP 50458 78 5 _ _ NNP 50458 78 6 , , , 50458 78 7 CXIV CXIV NNP 50458 78 8 , , , 50458 78 9 p. p. NN 50458 78 10 1256 1256 CD 50458 78 11 . . . 50458 79 1 _ _ NNP 50458 79 2 Ibid Ibid NNP 50458 79 3 . . . 50458 79 4 _ _ NNP 50458 79 5 , , , 50458 79 6 XCVII XCVII NNP 50458 79 7 , , , 50458 79 8 p. p. NN 50458 79 9 264 264 CD 50458 79 10 , , , 50458 79 11 and and CC 50458 79 12 XCIV xciv NN 50458 79 13 , , , 50458 79 14 p. p. NN 50458 79 15 1600 1600 CD 50458 79 16 . . . 50458 80 1 Phosphomolybdate phosphomolybdate NN 50458 80 2 is be VBZ 50458 80 3 then then RB 50458 80 4 added add VBN 50458 80 5 to to IN 50458 80 6 the the DT 50458 80 7 dialyzed dialyzed JJ 50458 80 8 liquid liquid NN 50458 80 9 , , , 50458 80 10 and and CC 50458 80 11 the the DT 50458 80 12 precipitate precipitate NN 50458 80 13 formed form VBN 50458 80 14 , , , 50458 80 15 which which WDT 50458 80 16 now now RB 50458 80 17 contains contain VBZ 50458 80 18 all all PDT 50458 80 19 the the DT 50458 80 20 bases basis NNS 50458 80 21 , , , 50458 80 22 decomposed decompose VBN 50458 80 23 by by IN 50458 80 24 boiling boil VBG 50458 80 25 with with IN 50458 80 26 lead lead JJ 50458 80 27 acetate acetate RB 50458 80 28 . . . 50458 81 1 After after IN 50458 81 2 removing remove VBG 50458 81 3 the the DT 50458 81 4 excess excess NN 50458 81 5 of of IN 50458 81 6 lead lead NN 50458 81 7 , , , 50458 81 8 there there EX 50458 81 9 is be VBZ 50458 81 10 thus thus RB 50458 81 11 obtained obtain VBN 50458 81 12 a a DT 50458 81 13 limpid limpid JJ 50458 81 14 solution solution NN 50458 81 15 of of IN 50458 81 16 all all PDT 50458 81 17 the the DT 50458 81 18 alkaloidal alkaloidal NN 50458 81 19 bases basis NNS 50458 81 20 in in IN 50458 81 21 the the DT 50458 81 22 form form NN 50458 81 23 of of IN 50458 81 24 acetates acetate NNS 50458 81 25 . . . 50458 82 1 These these DT 50458 82 2 are be VBP 50458 82 3 separated separate VBN 50458 82 4 by by IN 50458 82 5 alcohol alcohol NN 50458 82 6 and and CC 50458 82 7 by by IN 50458 82 8 means mean NNS 50458 82 9 of of IN 50458 82 10 fractional fractional JJ 50458 82 11 precipitations precipitation NNS 50458 82 12 with with IN 50458 82 13 various various JJ 50458 82 14 metallic metallic JJ 50458 82 15 salts salt NNS 50458 82 16 , , , 50458 82 17 depending depend VBG 50458 82 18 upon upon IN 50458 82 19 the the DT 50458 82 20 known know VBN 50458 82 21 properties property NNS 50458 82 22 of of IN 50458 82 23 the the DT 50458 82 24 bases basis NNS 50458 82 25 . . . 50458 83 1 In in IN 50458 83 2 order order NN 50458 83 3 to to TO 50458 83 4 facilitate facilitate VB 50458 83 5 their -PRON- PRP$ 50458 83 6 study study NN 50458 83 7 , , , 50458 83 8 the the DT 50458 83 9 ptomaines ptomaine NNS 50458 83 10 have have VBP 50458 83 11 been be VBN 50458 83 12 grouped group VBN 50458 83 13 under under IN 50458 83 14 two two CD 50458 83 15 distinct distinct JJ 50458 83 16 classes class NNS 50458 83 17 , , , 50458 83 18 the the DT 50458 83 19 one one NN 50458 83 20 embracing embrace VBG 50458 83 21 the the DT 50458 83 22 cadaveric cadaveric JJ 50458 83 23 or or CC 50458 83 24 putrefactive putrefactive JJ 50458 83 25 ptomaines ptomaine NNS 50458 83 26 , , , 50458 83 27 of of IN 50458 83 28 undetermined undetermined JJ 50458 83 29 microbial microbial JJ 50458 83 30 origin origin NN 50458 83 31 , , , 50458 83 32 the the DT 50458 83 33 other other JJ 50458 83 34 containing contain VBG 50458 83 35 the the DT 50458 83 36 ptomaines ptomaine NNS 50458 83 37 formed form VBN 50458 83 38 by by IN 50458 83 39 microbes microbe NNS 50458 83 40 of of IN 50458 83 41 known know VBN 50458 83 42 character character NN 50458 83 43 . . . 50458 84 1 Each each DT 50458 84 2 of of IN 50458 84 3 these these DT 50458 84 4 two two CD 50458 84 5 groups group NNS 50458 84 6 is be VBZ 50458 84 7 itself -PRON- PRP 50458 84 8 divided divide VBN 50458 84 9 into into IN 50458 84 10 subgroups subgroup NNS 50458 84 11 , , , 50458 84 12 as as IN 50458 84 13 shown show VBN 50458 84 14 in in IN 50458 84 15 the the DT 50458 84 16 following following JJ 50458 84 17 table table NN 50458 84 18 : : : 50458 84 19 GROUP GROUP NNP 50458 84 20 I. I. NNP 50458 85 1 = = NFP 50458 85 2 CADAVERIC CADAVERIC NNP 50458 85 3 PTOMAINES PTOMAINES NNP 50458 85 4 OF of IN 50458 85 5 UNDETERMINED UNDETERMINED NNP 50458 85 6 MICROBIAL MICROBIAL NNP 50458 85 7 ORIGIN.= ORIGIN.= NNP 50458 85 8 _ _ NNP 50458 85 9 a. a. NN 50458 85 10 _ _ NNP 50458 85 11 Amines Amines NNP 50458 85 12 . . . 50458 86 1 _ _ NNP 50458 86 2 b. b. NNP 50458 86 3 _ _ NNP 50458 86 4 Guanidines Guanidines NNP 50458 86 5 . . . 50458 87 1 _ _ NNP 50458 87 2 c. c. NNP 50458 87 3 _ _ NNP 50458 87 4 Oxamines Oxamines NNP 50458 87 5 ( ( -LRB- 50458 87 6 fatty fatty NNP 50458 87 7 or or CC 50458 87 8 aromatic aromatic JJ 50458 87 9 ) ) -RRB- 50458 87 10 . . . 50458 88 1 _ _ NNP 50458 88 2 d. d. NNP 50458 88 3 _ _ NNP 50458 88 4 Amido Amido NNP 50458 88 5 Acids Acids NNP 50458 88 6 . . . 50458 89 1 _ _ NNP 50458 89 2 e. e. NNP 50458 89 3 _ _ NNP 50458 89 4 Carbopyridic Carbopyridic NNP 50458 89 5 Acids Acids NNP 50458 89 6 and and CC 50458 89 7 analogues analogue NNS 50458 89 8 . . . 50458 90 1 _ _ NNP 50458 90 2 f. f. NNP 50458 90 3 _ _ NNP 50458 90 4 Undetermined Undetermined NNP 50458 90 5 Ptomaines Ptomaines NNP 50458 90 6 . . . 50458 91 1 GROUP GROUP NNP 50458 91 2 II II NNP 50458 91 3 . . . 50458 92 1 = = NFP 50458 92 2 PTOMAINES PTOMAINES NNP 50458 92 3 OF of IN 50458 92 4 KNOWN KNOWN NNP 50458 92 5 MICROBIAL MICROBIAL NNP 50458 92 6 ORIGIN.= ORIGIN.= NNPS 50458 92 7 _ _ NNP 50458 92 8 a. a. NN 50458 92 9 _ _ NNP 50458 92 10 Ptomaines Ptomaines NNP 50458 92 11 extracted extract VBD 50458 92 12 from from IN 50458 92 13 microbial microbial JJ 50458 92 14 cells cell NNS 50458 92 15 . . . 50458 93 1 _ _ NNP 50458 93 2 b. b. NN 50458 93 3 _ _ NNP 50458 93 4 Ptomaines Ptomaines NNP 50458 93 5 from from IN 50458 93 6 pathological pathological JJ 50458 93 7 urines urine NNS 50458 93 8 . . . 50458 94 1 We -PRON- PRP 50458 94 2 will will MD 50458 94 3 not not RB 50458 94 4 here here RB 50458 94 5 enter enter VB 50458 94 6 upon upon IN 50458 94 7 a a DT 50458 94 8 detailed detailed JJ 50458 94 9 study study NN 50458 94 10 of of IN 50458 94 11 the the DT 50458 94 12 bases basis NNS 50458 94 13 belonging belong VBG 50458 94 14 to to IN 50458 94 15 each each DT 50458 94 16 of of IN 50458 94 17 these these DT 50458 94 18 groups group NNS 50458 94 19 . . . 50458 95 1 This this DT 50458 95 2 subject subject NN 50458 95 3 is be VBZ 50458 95 4 a a DT 50458 95 5 vast vast JJ 50458 95 6 one one NN 50458 95 7 , , , 50458 95 8 requiring require VBG 50458 95 9 for for IN 50458 95 10 its -PRON- PRP$ 50458 95 11 treatment treatment NN 50458 95 12 a a DT 50458 95 13 volume volume NN 50458 95 14 devoted devote VBN 50458 95 15 to to IN 50458 95 16 it -PRON- PRP 50458 95 17 alone alone JJ 50458 95 18 . . . 50458 96 1 We -PRON- PRP 50458 96 2 will will MD 50458 96 3 here here RB 50458 96 4 simply simply RB 50458 96 5 touch touch VB 50458 96 6 upon upon IN 50458 96 7 the the DT 50458 96 8 principal principal JJ 50458 96 9 properties property NNS 50458 96 10 of of IN 50458 96 11 several several JJ 50458 96 12 of of IN 50458 96 13 the the DT 50458 96 14 bases basis NNS 50458 96 15 of of IN 50458 96 16 each each DT 50458 96 17 of of IN 50458 96 18 the the DT 50458 96 19 subgroups subgroup NNS 50458 96 20 named name VBN 50458 96 21 . . . 50458 97 1 BASES basis NNS 50458 97 2 OF of IN 50458 97 3 GROUP GROUP NNP 50458 97 4 I. I. NNP 50458 98 1 _ _ NNP 50458 98 2 a. a. NN 50458 98 3 _ _ NNP 50458 98 4 = = SYM 50458 98 5 Amines.=--Among Amines.=--Among `` 50458 98 6 these these DT 50458 98 7 we -PRON- PRP 50458 98 8 find find VBP 50458 98 9 nearly nearly RB 50458 98 10 all all PDT 50458 98 11 the the DT 50458 98 12 fatty fatty NN 50458 98 13 amines amine NNS 50458 98 14 , , , 50458 98 15 such such JJ 50458 98 16 as as IN 50458 98 17 the the DT 50458 98 18 methylamines methylamine NNS 50458 98 19 and and CC 50458 98 20 the the DT 50458 98 21 cyclic cyclic NN 50458 98 22 alkaloids alkaloid NNS 50458 98 23 such such JJ 50458 98 24 as as IN 50458 98 25 pyridine pyridine NNP 50458 98 26 . . . 50458 99 1 They -PRON- PRP 50458 99 2 are be VBP 50458 99 3 formed form VBN 50458 99 4 particularly particularly RB 50458 99 5 by by IN 50458 99 6 the the DT 50458 99 7 putrefaction putrefaction NN 50458 99 8 of of IN 50458 99 9 fish fish NN 50458 99 10 . . . 50458 100 1 Certain certain JJ 50458 100 2 of of IN 50458 100 3 these these DT 50458 100 4 bases basis NNS 50458 100 5 are be VBP 50458 100 6 very very RB 50458 100 7 toxic toxic JJ 50458 100 8 , , , 50458 100 9 for for IN 50458 100 10 instance instance NN 50458 100 11 trimethylene trimethylene NNP 50458 100 12 diamine diamine NNP 50458 100 13 , , , 50458 100 14 the the DT 50458 100 15 collidines collidine NNS 50458 100 16 , , , 50458 100 17 and and CC 50458 100 18 the the DT 50458 100 19 parvolines parvoline NNS 50458 100 20 . . . 50458 101 1 _ _ NNP 50458 101 2 b. b. NNP 50458 101 3 _ _ NNP 50458 101 4 = = SYM 50458 101 5 Guanidines.=--Among guanidines.=--among ADD 50458 101 6 the the DT 50458 101 7 products product NNS 50458 101 8 of of IN 50458 101 9 ordinary ordinary JJ 50458 101 10 putrefaction putrefaction NN 50458 101 11 there there EX 50458 101 12 has have VBZ 50458 101 13 been be VBN 50458 101 14 found find VBN 50458 101 15 so so RB 50458 101 16 far far RB 50458 101 17 only only JJ 50458 101 18 methylguanidine methylguanidine NN 50458 101 19 , , , 50458 101 20 C{2}H{7}N{3 C{2}H{7}N{3 NNP 50458 101 21 } } -RRB- 50458 101 22 . . . 50458 102 1 This this DT 50458 102 2 is be VBZ 50458 102 3 a a DT 50458 102 4 highly highly RB 50458 102 5 toxic toxic JJ 50458 102 6 base base NN 50458 102 7 of of IN 50458 102 8 which which WDT 50458 102 9 0.2 0.2 CD 50458 102 10 Gm Gm NNP 50458 102 11 . . . 50458 103 1 is be VBZ 50458 103 2 fatal fatal JJ 50458 103 3 to to IN 50458 103 4 a a DT 50458 103 5 guinea guinea NN 50458 103 6 - - HYPH 50458 103 7 pig pig NN 50458 103 8 . . . 50458 104 1 _ _ NNP 50458 104 2 c. c. NNP 50458 104 3 _ _ NNP 50458 104 4 = = SYM 50458 104 5 Oxamines.=--Under Oxamines.=--Under NNP 50458 104 6 this this DT 50458 104 7 designation designation NN 50458 104 8 the the DT 50458 104 9 following follow VBG 50458 104 10 bases basis NNS 50458 104 11 are be VBP 50458 104 12 comprised comprise VBN 50458 104 13 : : : 50458 104 14 1 1 CD 50458 104 15 . . . 50458 105 1 Neurine Neurine NNP 50458 105 2 bases basis NNS 50458 105 3 ; ; : 50458 105 4 2 2 LS 50458 105 5 . . . 50458 105 6 oxygenized oxygenized JJ 50458 105 7 aromatic aromatic JJ 50458 105 8 bases basis NNS 50458 105 9 ; ; : 50458 105 10 3 3 LS 50458 105 11 . . . 50458 105 12 bases basis NNS 50458 105 13 of of IN 50458 105 14 unknown unknown JJ 50458 105 15 constitution constitution NN 50458 105 16 . . . 50458 106 1 Amongst amongst IN 50458 106 2 them -PRON- PRP 50458 106 3 we -PRON- PRP 50458 106 4 find find VBP 50458 106 5 neurine neurine NN 50458 106 6 and and CC 50458 106 7 choline choline NN 50458 106 8 , , , 50458 106 9 which which WDT 50458 106 10 are be VBP 50458 106 11 toxic toxic JJ 50458 106 12 , , , 50458 106 13 and and CC 50458 106 14 betaine betaine JJ 50458 106 15 , , , 50458 106 16 which which WDT 50458 106 17 is be VBZ 50458 106 18 innocuous innocuous JJ 50458 106 19 . . . 50458 107 1 They -PRON- PRP 50458 107 2 are be VBP 50458 107 3 found find VBN 50458 107 4 particularly particularly RB 50458 107 5 in in IN 50458 107 6 putrid putrid JJ 50458 107 7 fish fish NN 50458 107 8 . . . 50458 108 1 _ _ NNP 50458 108 2 d. d. NNP 50458 108 3 _ _ NNP 50458 108 4 = = SYM 50458 108 5 Amido Amido NNP 50458 108 6 Acids.=--These Acids.=--These '' 50458 108 7 ptomaines ptomaine NNS 50458 108 8 , , , 50458 108 9 which which WDT 50458 108 10 are be VBP 50458 108 11 usually usually RB 50458 108 12 innocuous innocuous JJ 50458 108 13 in in IN 50458 108 14 small small JJ 50458 108 15 quantities quantity NNS 50458 108 16 , , , 50458 108 17 are be VBP 50458 108 18 particularly particularly RB 50458 108 19 the the DT 50458 108 20 products product NNS 50458 108 21 of of IN 50458 108 22 the the DT 50458 108 23 decomposition decomposition NN 50458 108 24 of of IN 50458 108 25 albuminoid albuminoid NN 50458 108 26 substances substance NNS 50458 108 27 . . . 50458 109 1 Among among IN 50458 109 2 them -PRON- PRP 50458 109 3 we -PRON- PRP 50458 109 4 find find VBP 50458 109 5 glycocoll glycocoll NN 50458 109 6 , , , 50458 109 7 leucine leucine NNP 50458 109 8 , , , 50458 109 9 and and CC 50458 109 10 tyrosine tyrosine NN 50458 109 11 , , , 50458 109 12 as as IN 50458 109 13 members member NNS 50458 109 14 of of IN 50458 109 15 this this DT 50458 109 16 group group NN 50458 109 17 . . . 50458 110 1 _ _ NNP 50458 110 2 e. e. NNP 50458 110 3 _ _ NNP 50458 110 4 = = SYM 50458 110 5 Carbopyridic Carbopyridic NNP 50458 110 6 and and CC 50458 110 7 Carboquinoleic Carboquinoleic NNP 50458 110 8 Acids.=--So Acids.=--So NNP 50458 110 9 far far RB 50458 110 10 only only RB 50458 110 11 one one CD 50458 110 12 base base NN 50458 110 13 is be VBZ 50458 110 14 known know VBN 50458 110 15 belonging belong VBG 50458 110 16 to to IN 50458 110 17 this this DT 50458 110 18 group group NN 50458 110 19 , , , 50458 110 20 and and CC 50458 110 21 that that DT 50458 110 22 is be VBZ 50458 110 23 morrhuic morrhuic NNS 50458 110 24 acid acid NNP 50458 110 25 , , , 50458 110 26 which which WDT 50458 110 27 is be VBZ 50458 110 28 found find VBN 50458 110 29 in in IN 50458 110 30 the the DT 50458 110 31 decomposed decompose VBN 50458 110 32 livers liver NNS 50458 110 33 of of IN 50458 110 34 codfish codfish NN 50458 110 35 , , , 50458 110 36 and and CC 50458 110 37 which which WDT 50458 110 38 is be VBZ 50458 110 39 a a DT 50458 110 40 powerful powerful JJ 50458 110 41 appetizer appetizer NN 50458 110 42 and and CC 50458 110 43 stimulant stimulant NN 50458 110 44 in in IN 50458 110 45 disassimilation disassimilation NN 50458 110 46 . . . 50458 111 1 _ _ NNP 50458 111 2 f. f. NNP 50458 111 3 _ _ NNP 50458 111 4 = = SYM 50458 111 5 Undetermined Undetermined NNP 50458 111 6 Ptomaines.=--Under Ptomaines.=--Under NNP 50458 111 7 this this DT 50458 111 8 heading heading NN 50458 111 9 are be VBP 50458 111 10 classed class VBN 50458 111 11 certain certain JJ 50458 111 12 undetermined undetermined JJ 50458 111 13 bases basis NNS 50458 111 14 , , , 50458 111 15 such such JJ 50458 111 16 as as IN 50458 111 17 those those DT 50458 111 18 found find VBN 50458 111 19 in in IN 50458 111 20 normal normal JJ 50458 111 21 urines urine NNS 50458 111 22 , , , 50458 111 23 and and CC 50458 111 24 in in IN 50458 111 25 spoiled spoiled JJ 50458 111 26 meats meat NNS 50458 111 27 and and CC 50458 111 28 bread bread NN 50458 111 29 . . . 50458 112 1 BASES basis NNS 50458 112 2 OF of IN 50458 112 3 GROUP GROUP NNP 50458 112 4 II II NNP 50458 112 5 . . . 50458 113 1 _ _ NNP 50458 113 2 a. a. NN 50458 113 3 _ _ NNP 50458 113 4 = = SYM 50458 113 5 Ptomaines Ptomaines NNP 50458 113 6 Isolated isolate VBN 50458 113 7 from from IN 50458 113 8 Cultures culture NNS 50458 113 9 of of IN 50458 113 10 Pathogenic pathogenic JJ 50458 113 11 Bacteria.=--Bacterial bacteria.=--bacterial JJ 50458 113 12 cultures culture NNS 50458 113 13 contain contain VBP 50458 113 14 , , , 50458 113 15 besides besides IN 50458 113 16 the the DT 50458 113 17 true true JJ 50458 113 18 toxins toxin NNS 50458 113 19 , , , 50458 113 20 a a DT 50458 113 21 certain certain JJ 50458 113 22 number number NN 50458 113 23 of of IN 50458 113 24 alkaloidal alkaloidal NN 50458 113 25 bases basis NNS 50458 113 26 which which WDT 50458 113 27 sometimes sometimes RB 50458 113 28 possess possess VBP 50458 113 29 considerable considerable JJ 50458 113 30 toxicity toxicity NN 50458 113 31 . . . 50458 114 1 In in IN 50458 114 2 the the DT 50458 114 3 cultures culture NNS 50458 114 4 of of IN 50458 114 5 streptococcus streptococcus NN 50458 114 6 pyogenes pyogene NNS 50458 114 7 there there EX 50458 114 8 are be VBP 50458 114 9 found find VBN 50458 114 10 trimethylamine trimethylamine NN 50458 114 11 and and CC 50458 114 12 xanthic xanthic JJ 50458 114 13 bases basis NNS 50458 114 14 ; ; : 50458 114 15 in in IN 50458 114 16 those those DT 50458 114 17 of of IN 50458 114 18 staphylococcus staphylococcus NN 50458 114 19 pyogenes pyogene NNS 50458 114 20 aureus aureus NNP 50458 114 21 are be VBP 50458 114 22 found find VBN 50458 114 23 xanthic xanthic JJ 50458 114 24 bases basis NNS 50458 114 25 and and CC 50458 114 26 creatinine creatinine NN 50458 114 27 ; ; : 50458 114 28 while while IN 50458 114 29 pyocyanine pyocyanine NN 50458 114 30 and and CC 50458 114 31 pyoxanthine pyoxanthine NN 50458 114 32 are be VBP 50458 114 33 found find VBN 50458 114 34 in in IN 50458 114 35 the the DT 50458 114 36 cultures culture NNS 50458 114 37 of of IN 50458 114 38 bacillus bacillus NN 50458 114 39 pyocyaneus pyocyaneu NNS 50458 114 40 , , , 50458 114 41 etc etc FW 50458 114 42 . . . 50458 115 1 _ _ NNP 50458 115 2 b. b. NNP 50458 115 3 _ _ NNP 50458 115 4 = = SYM 50458 115 5 Ptomaines Ptomaines NNP 50458 115 6 Isolated isolate VBN 50458 115 7 from from IN 50458 115 8 Pathological pathological JJ 50458 115 9 Urines.=--Toxic urines.=--toxic JJ 50458 115 10 ptomaine ptomaine NN 50458 115 11 bases basis NNS 50458 115 12 have have VBP 50458 115 13 been be VBN 50458 115 14 found find VBN 50458 115 15 in in IN 50458 115 16 the the DT 50458 115 17 urines urine NNS 50458 115 18 of of IN 50458 115 19 a a DT 50458 115 20 large large JJ 50458 115 21 number number NN 50458 115 22 of of IN 50458 115 23 diseases disease NNS 50458 115 24 . . . 50458 116 1 [ [ -LRB- 50458 116 2 8 8 CD 50458 116 3 ] ] -RRB- 50458 116 4 It -PRON- PRP 50458 116 5 is be VBZ 50458 116 6 quite quite RB 50458 116 7 probable probable JJ 50458 116 8 that that IN 50458 116 9 these these DT 50458 116 10 bases basis NNS 50458 116 11 are be VBP 50458 116 12 the the DT 50458 116 13 results result NNS 50458 116 14 of of IN 50458 116 15 a a DT 50458 116 16 general general JJ 50458 116 17 pathological pathological JJ 50458 116 18 condition condition NN 50458 116 19 due due JJ 50458 116 20 to to IN 50458 116 21 some some DT 50458 116 22 bacterial bacterial JJ 50458 116 23 disease disease NN 50458 116 24 , , , 50458 116 25 the the DT 50458 116 26 toxic toxic JJ 50458 116 27 products product NNS 50458 116 28 of of IN 50458 116 29 which which WDT 50458 116 30 are be VBP 50458 116 31 eliminated eliminate VBN 50458 116 32 by by IN 50458 116 33 the the DT 50458 116 34 kidneys kidney NNS 50458 116 35 . . . 50458 117 1 [ [ -LRB- 50458 117 2 8 8 CD 50458 117 3 ] ] -RRB- 50458 117 4 GRIFFITHS GRIFFITHS NNP 50458 117 5 : : : 50458 117 6 _ _ NNP 50458 117 7 C. C. NNP 50458 118 1 rend rend VB 50458 118 2 . . . 50458 119 1 de de NNP 50458 119 2 l'Académie l'Académie NNP 50458 119 3 des des NNP 50458 119 4 Sciences Sciences NNP 50458 119 5 _ _ NNP 50458 119 6 , , , 50458 119 7 CXV CXV NNP 50458 119 8 , , , 50458 119 9 pp pp NNP 50458 119 10 . . . 50458 120 1 285 285 CD 50458 120 2 and and CC 50458 120 3 667 667 CD 50458 120 4 . . . 50458 121 1 From from IN 50458 121 2 the the DT 50458 121 3 urines urine NNS 50458 121 4 of of IN 50458 121 5 epileptics epileptic NNS 50458 121 6 Griffiths[9 griffiths[9 NN 50458 121 7 ] ] -RRB- 50458 121 8 isolated isolate VBD 50458 121 9 a a DT 50458 121 10 colorless colorless JJ 50458 121 11 base base NN 50458 121 12 crystallizing crystallize VBG 50458 121 13 in in IN 50458 121 14 prisms prism NNS 50458 121 15 having have VBG 50458 121 16 the the DT 50458 121 17 formula formula NN 50458 121 18 C{12}H{15}N{5}O{7 C{12}H{15}N{5}O{7 : 50458 121 19 } } -RRB- 50458 121 20 , , , 50458 121 21 and and CC 50458 121 22 which which WDT 50458 121 23 was be VBD 50458 121 24 found find VBN 50458 121 25 to to TO 50458 121 26 be be VB 50458 121 27 exceedingly exceedingly RB 50458 121 28 toxic toxic JJ 50458 121 29 ; ; : 50458 121 30 the the DT 50458 121 31 same same JJ 50458 121 32 investigator investigator NN 50458 121 33 isolated isolate VBD 50458 121 34 from from IN 50458 121 35 the the DT 50458 121 36 urines urine NNS 50458 121 37 of of IN 50458 121 38 eczematous eczematous JJ 50458 121 39 subjects subject NNS 50458 121 40 a a DT 50458 121 41 ptomaine ptomaine NN 50458 121 42 which which WDT 50458 121 43 he -PRON- PRP 50458 121 44 named name VBD 50458 121 45 _ _ NNP 50458 121 46 eczemine_,[10 eczemine_,[10 NNP 50458 121 47 ] ] -RRB- 50458 121 48 and and CC 50458 121 49 which which WDT 50458 121 50 is be VBZ 50458 121 51 also also RB 50458 121 52 highly highly RB 50458 121 53 toxic toxic JJ 50458 121 54 . . . 50458 122 1 [ [ -LRB- 50458 122 2 9 9 CD 50458 122 3 ] ] -RRB- 50458 122 4 E. E. NNP 50458 122 5 POUCHET POUCHET NNP 50458 122 6 : : : 50458 122 7 Contribution Contribution NNP 50458 122 8 à à NNP 50458 122 9 l'étude l'étude NNP 50458 122 10 des des NNP 50458 122 11 matières matière NNS 50458 122 12 extractives extractive NNS 50458 122 13 de de NNP 50458 122 14 l'urine l'urine NNP 50458 122 15 , , , 50458 122 16 _ _ NNP 50458 122 17 Thèse Thèse NNP 50458 122 18 _ _ NNP 50458 122 19 , , , 50458 122 20 Paris Paris NNP 50458 122 21 , , , 50458 122 22 1880 1880 CD 50458 122 23 ; ; : 50458 122 24 _ _ NNP 50458 122 25 Ibid Ibid NNP 50458 122 26 . . . 50458 122 27 _ _ NNP 50458 122 28 , , , 50458 122 29 _ _ NNP 50458 122 30 C. C. NNP 50458 123 1 rend rend VB 50458 123 2 . . . 50458 124 1 de de NNP 50458 124 2 l'Académie l'Académie NNP 50458 124 3 des des NNP 50458 124 4 Sc Sc NNP 50458 124 5 . . . 50458 124 6 _ _ NNP 50458 124 7 , , , 50458 124 8 XCVII XCVII NNP 50458 124 9 , , , 50458 124 10 p. p. NN 50458 124 11 1560 1560 CD 50458 124 12 ; ; : 50458 124 13 BOUCHARD BOUCHARD NNP 50458 124 14 : : : 50458 124 15 _ _ NNP 50458 124 16 C. C. NNP 50458 125 1 rend rend VB 50458 125 2 . . . 50458 126 1 Soc Soc NNP 50458 126 2 . . . 50458 127 1 de de NNP 50458 127 2 Biolog Biolog NNP 50458 127 3 . . . 50458 127 4 _ _ NNP 50458 127 5 , , , 50458 127 6 Aug. August NNP 50458 127 7 12 12 CD 50458 127 8 , , , 50458 127 9 1882 1882 CD 50458 127 10 . . . 50458 128 1 [ [ -LRB- 50458 128 2 10 10 CD 50458 128 3 ] ] -RRB- 50458 128 4 GRIFFITHS GRIFFITHS NNP 50458 128 5 : : : 50458 128 6 _ _ NNP 50458 128 7 C. C. NNP 50458 129 1 rend rend VB 50458 129 2 . . . 50458 130 1 de de NNP 50458 130 2 l'Académie l'Académie NNP 50458 130 3 des des NNP 50458 130 4 Sciences Sciences NNP 50458 130 5 _ _ NNP 50458 130 6 , , , 50458 130 7 CXVI CXVI NNP 50458 130 8 , , , 50458 130 9 p. p. NN 50458 130 10 1206 1206 CD 50458 130 11 . . . 50458 131 1 In in IN 50458 131 2 certain certain JJ 50458 131 3 cases case NNS 50458 131 4 of of IN 50458 131 5 cystinuria cystinuria NNS 50458 131 6 there there EX 50458 131 7 are be VBP 50458 131 8 found find VBN 50458 131 9 in in IN 50458 131 10 the the DT 50458 131 11 urine urine NN 50458 131 12 sulphurized sulphurize VBD 50458 131 13 ptomaines ptomaine NNS 50458 131 14 , , , 50458 131 15 and and CC 50458 131 16 in in IN 50458 131 17 measles measle NNS 50458 131 18 the the DT 50458 131 19 urine urine NN 50458 131 20 contains contain VBZ 50458 131 21 an an DT 50458 131 22 undetermined undetermined JJ 50458 131 23 ptomaine ptomaine NN 50458 131 24 , , , 50458 131 25 _ _ NNP 50458 131 26 rubedine rubedine NNP 50458 131 27 _ _ NNP 50458 131 28 , , , 50458 131 29 which which WDT 50458 131 30 is be VBZ 50458 131 31 very very RB 50458 131 32 poisonous poisonous JJ 50458 131 33 . . . 50458 132 1 _ _ NNP 50458 132 2 Typhotoxine Typhotoxine NNP 50458 132 3 _ _ NNP 50458 132 4 , , , 50458 132 5 a a DT 50458 132 6 very very RB 50458 132 7 toxic toxic JJ 50458 132 8 ptomaine ptomaine NN 50458 132 9 , , , 50458 132 10 has have VBZ 50458 132 11 been be VBN 50458 132 12 isolated isolate VBN 50458 132 13 from from IN 50458 132 14 the the DT 50458 132 15 urine urine NN 50458 132 16 of of IN 50458 132 17 typhoid typhoid NN 50458 132 18 patients patient NNS 50458 132 19 ; ; : 50458 132 20 _ _ NNP 50458 132 21 erysipeline erysipeline NN 50458 132 22 _ _ NNP 50458 132 23 , , , 50458 132 24 a a DT 50458 132 25 hardly hardly RB 50458 132 26 less less RBR 50458 132 27 toxic toxic JJ 50458 132 28 base base NN 50458 132 29 , , , 50458 132 30 exists exist VBZ 50458 132 31 in in IN 50458 132 32 the the DT 50458 132 33 urine urine NN 50458 132 34 of of IN 50458 132 35 erysipelatic erysipelatic JJ 50458 132 36 subjects subject NNS 50458 132 37 ; ; : 50458 132 38 while while IN 50458 132 39 _ _ NNP 50458 132 40 spasmotoxine spasmotoxine NN 50458 132 41 _ _ NNP 50458 132 42 , , , 50458 132 43 _ _ NNP 50458 132 44 tetanotoxine tetanotoxine NN 50458 132 45 _ _ NNP 50458 132 46 , , , 50458 132 47 and and CC 50458 132 48 _ _ NNP 50458 132 49 tetanine tetanine NN 50458 132 50 _ _ NNP 50458 132 51 , , , 50458 132 52 exceedingly exceedingly RB 50458 132 53 active active JJ 50458 132 54 alkaloids alkaloid NNS 50458 132 55 , , , 50458 132 56 are be VBP 50458 132 57 found find VBN 50458 132 58 in in IN 50458 132 59 the the DT 50458 132 60 urines urine NNS 50458 132 61 of of IN 50458 132 62 tetanus tetanus NN 50458 132 63 patients patient NNS 50458 132 64 . . . 50458 133 1 [ [ -LRB- 50458 133 2 11 11 CD 50458 133 3 ] ] -RRB- 50458 133 4 [ [ -LRB- 50458 133 5 11 11 CD 50458 133 6 ] ] -RRB- 50458 133 7 BRIEGER BRIEGER NNP 50458 133 8 : : : 50458 133 9 Untersuchungen Untersuchungen NNP 50458 133 10 über über NN 50458 133 11 die die VBP 50458 133 12 Ptomaine Ptomaine NNP 50458 133 13 , , , 50458 133 14 dritten dritten JJ 50458 133 15 Teil Teil NNP 50458 133 16 , , , 50458 133 17 p. p. NN 50458 133 18 93 93 CD 50458 133 19 ; ; : 50458 133 20 _ _ NNP 50458 133 21 Berichte Berichte NNP 50458 133 22 d. d. NNP 50458 133 23 D. D. NNP 50458 133 24 Chem Chem NNP 50458 133 25 . . . 50458 134 1 Gesellschaft Gesellschaft NNP 50458 134 2 _ _ NNP 50458 134 3 , , , 50458 134 4 1886 1886 CD 50458 134 5 , , , 50458 134 6 p. p. NN 50458 134 7 3159 3159 CD 50458 134 8 ; ; : 50458 134 9 1887 1887 CD 50458 134 10 , , , 50458 134 11 p. p. NN 50458 134 12 69 69 CD 50458 134 13 . . . 50458 135 1 As as IN 50458 135 2 a a DT 50458 135 3 general general JJ 50458 135 4 rule rule NN 50458 135 5 , , , 50458 135 6 all all DT 50458 135 7 abnormal abnormal JJ 50458 135 8 urines urine NNS 50458 135 9 contain contain VBP 50458 135 10 toxic toxic JJ 50458 135 11 bases basis NNS 50458 135 12 ; ; : 50458 135 13 the the DT 50458 135 14 kidneys kidney NNS 50458 135 15 appear appear VBP 50458 135 16 , , , 50458 135 17 in in IN 50458 135 18 fact fact NN 50458 135 19 , , , 50458 135 20 to to TO 50458 135 21 serve serve VB 50458 135 22 as as IN 50458 135 23 a a DT 50458 135 24 means means NN 50458 135 25 of of IN 50458 135 26 eliminating eliminate VBG 50458 135 27 the the DT 50458 135 28 toxic toxic JJ 50458 135 29 products product NNS 50458 135 30 that that WDT 50458 135 31 form form VBP 50458 135 32 in in IN 50458 135 33 large large JJ 50458 135 34 quantity quantity NN 50458 135 35 whenever whenever WRB 50458 135 36 , , , 50458 135 37 and and CC 50458 135 38 for for IN 50458 135 39 whatever whatever WDT 50458 135 40 cause cause NN 50458 135 41 , , , 50458 135 42 the the DT 50458 135 43 organism organism NN 50458 135 44 ceases cease VBZ 50458 135 45 to to TO 50458 135 46 functionate functionate VB 50458 135 47 normally normally RB 50458 135 48 , , , 50458 135 49 whether whether IN 50458 135 50 it -PRON- PRP 50458 135 51 be be VB 50458 135 52 as as IN 50458 135 53 a a DT 50458 135 54 whole whole NN 50458 135 55 , , , 50458 135 56 or or CC 50458 135 57 in in IN 50458 135 58 any any DT 50458 135 59 one one CD 50458 135 60 of of IN 50458 135 61 its -PRON- PRP$ 50458 135 62 parts part NNS 50458 135 63 . . . 50458 136 1 [ [ -LRB- 50458 136 2 12 12 CD 50458 136 3 ] ] -RRB- 50458 136 4 [ [ -LRB- 50458 136 5 12 12 CD 50458 136 6 ] ] -RRB- 50458 136 7 CHARRIN CHARRIN NNP 50458 136 8 : : : 50458 136 9 _ _ NNP 50458 136 10 Les Les NNP 50458 136 11 poisons poison NNS 50458 136 12 de de IN 50458 136 13 l'urine l'urine NNP 50458 136 14 _ _ NNP 50458 136 15 : : : 50458 136 16 Encyclopédie Encyclopédie NNP 50458 136 17 Léauté Léauté NNP 50458 136 18 . . . 50458 137 1 = = NFP 50458 137 2 Leucomaines.=[13 Leucomaines.=[13 NNS 50458 137 3 ] ] -RRB- 50458 137 4 [ [ -LRB- 50458 137 5 13 13 CD 50458 137 6 ] ] -RRB- 50458 137 7 ARMAND ARMAND NNP 50458 137 8 GAUTIER GAUTIER NNP 50458 137 9 : : : 50458 137 10 _ _ NNP 50458 137 11 Bull Bull NNP 50458 137 12 . . . 50458 138 1 Acad Acad NNS 50458 138 2 . . . 50458 139 1 de de NNP 50458 139 2 Médecin Médecin NNP 50458 139 3 _ _ NNP 50458 139 4 ( ( -LRB- 50458 139 5 2 2 CD 50458 139 6 ) ) -RRB- 50458 139 7 , , , 50458 139 8 XV XV NNP 50458 139 9 , , , 50458 139 10 p. p. NN 50458 139 11 115 115 CD 50458 139 12 . . . 50458 140 1 The the DT 50458 140 2 leucomaines leucomaine NNS 50458 140 3 are be VBP 50458 140 4 basic basic JJ 50458 140 5 substances substance NNS 50458 140 6 , , , 50458 140 7 nearly nearly RB 50458 140 8 allied ally VBN 50458 140 9 to to IN 50458 140 10 the the DT 50458 140 11 ptomaines ptomaine NNS 50458 140 12 , , , 50458 140 13 but but CC 50458 140 14 still still RB 50458 140 15 more more RBR 50458 140 16 closely closely RB 50458 140 17 related related JJ 50458 140 18 to to IN 50458 140 19 the the DT 50458 140 20 ureides ureide NNS 50458 140 21 . . . 50458 141 1 They -PRON- PRP 50458 141 2 are be VBP 50458 141 3 formed form VBN 50458 141 4 directly directly RB 50458 141 5 or or CC 50458 141 6 indirectly indirectly RB 50458 141 7 by by IN 50458 141 8 the the DT 50458 141 9 breaking break VBG 50458 141 10 down down RP 50458 141 11 of of IN 50458 141 12 protoplasmal protoplasmal JJ 50458 141 13 albuminoids albuminoid NNS 50458 141 14 . . . 50458 142 1 The the DT 50458 142 2 agents agent NNS 50458 142 3 that that WDT 50458 142 4 effect effect VBP 50458 142 5 the the DT 50458 142 6 breaking break VBG 50458 142 7 down down RP 50458 142 8 are be VBP 50458 142 9 the the DT 50458 142 10 hydrolyzing hydrolyze VBG 50458 142 11 ferments ferment NNS 50458 142 12 of of IN 50458 142 13 the the DT 50458 142 14 economy economy NN 50458 142 15 . . . 50458 143 1 It -PRON- PRP 50458 143 2 is be VBZ 50458 143 3 well well JJ 50458 143 4 to to TO 50458 143 5 recall recall VB 50458 143 6 here here RB 50458 143 7 that that IN 50458 143 8 these these DT 50458 143 9 phenomena phenomenon NNS 50458 143 10 of of IN 50458 143 11 hydrolyzation hydrolyzation NN 50458 143 12 occur occur VBP 50458 143 13 within within IN 50458 143 14 the the DT 50458 143 15 cell cell NN 50458 143 16 itself -PRON- PRP 50458 143 17 and and CC 50458 143 18 in in IN 50458 143 19 a a DT 50458 143 20 practically practically RB 50458 143 21 reducing reduce VBG 50458 143 22 medium medium NN 50458 143 23 , , , 50458 143 24 as as IN 50458 143 25 we -PRON- PRP 50458 143 26 have have VBP 50458 143 27 already already RB 50458 143 28 stated state VBN 50458 143 29 . . . 50458 144 1 The the DT 50458 144 2 inmost inmost JJ 50458 144 3 mechanism mechanism NN 50458 144 4 of of IN 50458 144 5 these these DT 50458 144 6 phenomena phenomenon NNS 50458 144 7 can can MD 50458 144 8 not not RB 50458 144 9 here here RB 50458 144 10 be be VB 50458 144 11 detailed detailed JJ 50458 144 12 ; ; : 50458 144 13 it -PRON- PRP 50458 144 14 will will MD 50458 144 15 be be VB 50458 144 16 found find VBN 50458 144 17 described describe VBN 50458 144 18 by by IN 50458 144 19 Armand Armand NNP 50458 144 20 Gautier Gautier NNP 50458 144 21 in in IN 50458 144 22 the the DT 50458 144 23 _ _ NNP 50458 144 24 Chimie Chimie NNP 50458 144 25 Biologique Biologique NNP 50458 144 26 _ _ NNP 50458 144 27 , , , 50458 144 28 and and CC 50458 144 29 in in IN 50458 144 30 his -PRON- PRP$ 50458 144 31 work work NN 50458 144 32 _ _ NNP 50458 144 33 Chimie Chimie NNP 50458 144 34 de de NNP 50458 144 35 la la NNP 50458 144 36 Cellule Cellule NNP 50458 144 37 Vivante Vivante NNP 50458 144 38 _ _ NNP 50458 144 39 . . . 50458 145 1 [ [ -LRB- 50458 145 2 14 14 CD 50458 145 3 ] ] -RRB- 50458 145 4 [ [ -LRB- 50458 145 5 14 14 CD 50458 145 6 ] ] -RRB- 50458 145 7 ARMAND ARMAND NNP 50458 145 8 GAUTIER GAUTIER NNP 50458 145 9 : : : 50458 145 10 Leçons Leçons NNP 50458 145 11 de de NNP 50458 145 12 chimie chimie NNP 50458 145 13 biologique biologique NNP 50458 145 14 . . . 50458 146 1 Published publish VBN 50458 146 2 by by IN 50458 146 3 Masson Masson NNP 50458 146 4 ; ; : 50458 146 5 _ _ NNP 50458 146 6 Ibid Ibid NNP 50458 146 7 . . . 50458 146 8 _ _ NNP 50458 146 9 , , , 50458 146 10 Chimie Chimie NNP 50458 146 11 de de NNP 50458 146 12 la la NNP 50458 146 13 cellule cellule NNP 50458 146 14 vivante vivante NNP 50458 146 15 . . . 50458 147 1 Also also RB 50458 147 2 published publish VBN 50458 147 3 by by IN 50458 147 4 Masson Masson NNP 50458 147 5 . . . 50458 148 1 The the DT 50458 148 2 extraction extraction NN 50458 148 3 of of IN 50458 148 4 these these DT 50458 148 5 bases basis NNS 50458 148 6 is be VBZ 50458 148 7 an an DT 50458 148 8 extremely extremely RB 50458 148 9 delicate delicate JJ 50458 148 10 operation operation NN 50458 148 11 . . . 50458 149 1 It -PRON- PRP 50458 149 2 is be VBZ 50458 149 3 necessary necessary JJ 50458 149 4 to to TO 50458 149 5 operate operate VB 50458 149 6 with with IN 50458 149 7 a a DT 50458 149 8 large large JJ 50458 149 9 quantity quantity NN 50458 149 10 of of IN 50458 149 11 substance substance NN 50458 149 12 , , , 50458 149 13 say say VBP 50458 149 14 50 50 CD 50458 149 15 kilos kilo NNS 50458 149 16 . . . 50458 150 1 The the DT 50458 150 2 substance substance NN 50458 150 3 is be VBZ 50458 150 4 finely finely RB 50458 150 5 chopped chop VBN 50458 150 6 , , , 50458 150 7 then then RB 50458 150 8 exhausted exhaust VBN 50458 150 9 with with IN 50458 150 10 twice twice PDT 50458 150 11 its -PRON- PRP$ 50458 150 12 weight weight NN 50458 150 13 of of IN 50458 150 14 water water NN 50458 150 15 acidulated acidulate VBN 50458 150 16 with with IN 50458 150 17 acetic acetic JJ 50458 150 18 acid acid NN 50458 150 19 ( ( -LRB- 50458 150 20 0.2 0.2 CD 50458 150 21 Cc Cc NNP 50458 150 22 . . . 50458 151 1 per per IN 50458 151 2 liter liter RB 50458 151 3 ) ) -RRB- 50458 151 4 and and CC 50458 151 5 containing contain VBG 50458 151 6 a a DT 50458 151 7 trace trace NN 50458 151 8 of of IN 50458 151 9 oil oil NN 50458 151 10 of of IN 50458 151 11 mustard mustard NN 50458 151 12 , , , 50458 151 13 which which WDT 50458 151 14 is be VBZ 50458 151 15 intended intend VBN 50458 151 16 to to TO 50458 151 17 act act VB 50458 151 18 as as IN 50458 151 19 an an DT 50458 151 20 antiseptic antiseptic NN 50458 151 21 . . . 50458 152 1 The the DT 50458 152 2 albuminoids albuminoid NNS 50458 152 3 are be VBP 50458 152 4 precipitated precipitate VBN 50458 152 5 by by IN 50458 152 6 boiling boil VBG 50458 152 7 , , , 50458 152 8 the the DT 50458 152 9 solution solution NN 50458 152 10 then then RB 50458 152 11 filtered filter VBD 50458 152 12 , , , 50458 152 13 evaporated evaporate VBD 50458 152 14 in in IN 50458 152 15 a a DT 50458 152 16 vacuum vacuum NN 50458 152 17 at at IN 50458 152 18 60 60 CD 50458 152 19 ° ° NNS 50458 152 20 C. C. NNP 50458 152 21 , , , 50458 152 22 and and CC 50458 152 23 the the DT 50458 152 24 bases basis NNS 50458 152 25 extracted extract VBN 50458 152 26 with with IN 50458 152 27 95-per 95-per CD 50458 152 28 cent cent NN 50458 152 29 . . . 50458 153 1 alcohol alcohol NN 50458 153 2 . . . 50458 154 1 The the DT 50458 154 2 alkaloidal alkaloidal NN 50458 154 3 bases basis NNS 50458 154 4 obtained obtain VBN 50458 154 5 in in IN 50458 154 6 this this DT 50458 154 7 manner manner NN 50458 154 8 are be VBP 50458 154 9 separated separate VBN 50458 154 10 by by IN 50458 154 11 crystallization crystallization NN 50458 154 12 from from IN 50458 154 13 alcohol alcohol NN 50458 154 14 or or CC 50458 154 15 by by IN 50458 154 16 various various JJ 50458 154 17 other other JJ 50458 154 18 chemical chemical NN 50458 154 19 methods method NNS 50458 154 20 , , , 50458 154 21 the the DT 50458 154 22 description description NN 50458 154 23 of of IN 50458 154 24 which which WDT 50458 154 25 we -PRON- PRP 50458 154 26 will will MD 50458 154 27 not not RB 50458 154 28 enter enter VB 50458 154 29 upon upon IN 50458 154 30 here here RB 50458 154 31 . . . 50458 155 1 In in IN 50458 155 2 order order NN 50458 155 3 to to TO 50458 155 4 facilitate facilitate VB 50458 155 5 the the DT 50458 155 6 study study NN 50458 155 7 of of IN 50458 155 8 the the DT 50458 155 9 leucomaines leucomaine NNS 50458 155 10 they -PRON- PRP 50458 155 11 are be VBP 50458 155 12 classed class VBN 50458 155 13 under under IN 50458 155 14 three three CD 50458 155 15 groups group NNS 50458 155 16 , , , 50458 155 17 according accord VBG 50458 155 18 to to IN 50458 155 19 their -PRON- PRP$ 50458 155 20 chemical chemical JJ 50458 155 21 affinities affinity NNS 50458 155 22 . . . 50458 156 1 These these DT 50458 156 2 groups group NNS 50458 156 3 are be VBP 50458 156 4 as as IN 50458 156 5 follows follow VBZ 50458 156 6 : : : 50458 156 7 1 1 CD 50458 156 8 . . . 50458 157 1 = = NFP 50458 157 2 Xanthic xanthic VB 50458 157 3 Leucomaines.=--The leucomaines.=--the NN 50458 157 4 bases basis NNS 50458 157 5 of of IN 50458 157 6 this this DT 50458 157 7 group group NN 50458 157 8 appear appear VBP 50458 157 9 to to TO 50458 157 10 have have VB 50458 157 11 a a DT 50458 157 12 composition composition NN 50458 157 13 resembling resemble VBG 50458 157 14 that that DT 50458 157 15 of of IN 50458 157 16 uric uric JJ 50458 157 17 acid acid NN 50458 157 18 . . . 50458 158 1 When when WRB 50458 158 2 hydrolyzed hydrolyze VBN 50458 158 3 , , , 50458 158 4 they -PRON- PRP 50458 158 5 yield yield VBP 50458 158 6 urea urea NNP 50458 158 7 and and CC 50458 158 8 guanidine guanidine NNP 50458 158 9 . . . 50458 159 1 They -PRON- PRP 50458 159 2 are be VBP 50458 159 3 weak weak JJ 50458 159 4 bases basis NNS 50458 159 5 , , , 50458 159 6 and and CC 50458 159 7 exhibit exhibit VB 50458 159 8 both both CC 50458 159 9 basic basic JJ 50458 159 10 and and CC 50458 159 11 weakly weakly JJ 50458 159 12 acid acid JJ 50458 159 13 properties property NNS 50458 159 14 . . . 50458 160 1 They -PRON- PRP 50458 160 2 all all DT 50458 160 3 possess possess VBP 50458 160 4 the the DT 50458 160 5 common common JJ 50458 160 6 characteristic characteristic NN 50458 160 7 of of IN 50458 160 8 being be VBG 50458 160 9 precipitated precipitate VBN 50458 160 10 by by IN 50458 160 11 copper copper NN 50458 160 12 acetate acetate NN 50458 160 13 in in IN 50458 160 14 acid acid JJ 50458 160 15 solution solution NN 50458 160 16 with with IN 50458 160 17 heat heat NN 50458 160 18 , , , 50458 160 19 and and CC 50458 160 20 by by IN 50458 160 21 ammoniacal ammoniacal JJ 50458 160 22 silver silver NN 50458 160 23 nitrate nitrate JJ 50458 160 24 in in IN 50458 160 25 the the DT 50458 160 26 cold cold NN 50458 160 27 . . . 50458 161 1 According accord VBG 50458 161 2 to to IN 50458 161 3 Kossel Kossel NNP 50458 161 4 , , , 50458 161 5 these these DT 50458 161 6 bases basis NNS 50458 161 7 are be VBP 50458 161 8 derived derive VBN 50458 161 9 from from IN 50458 161 10 the the DT 50458 161 11 nucleo nucleo NNP 50458 161 12 - - HYPH 50458 161 13 albumins albumin NNS 50458 161 14 which which WDT 50458 161 15 are be VBP 50458 161 16 found find VBN 50458 161 17 in in IN 50458 161 18 the the DT 50458 161 19 cell cell NN 50458 161 20 nuclei nucleus NNS 50458 161 21 , , , 50458 161 22 and and CC 50458 161 23 which which WDT 50458 161 24 are be VBP 50458 161 25 , , , 50458 161 26 as as IN 50458 161 27 we -PRON- PRP 50458 161 28 know know VBP 50458 161 29 , , , 50458 161 30 substances substance VBZ 50458 161 31 rich rich JJ 50458 161 32 in in IN 50458 161 33 nitrogen nitrogen NN 50458 161 34 and and CC 50458 161 35 phosphorus phosphorus NN 50458 161 36 . . . 50458 162 1 Among among IN 50458 162 2 the the DT 50458 162 3 bases basis NNS 50458 162 4 of of IN 50458 162 5 this this DT 50458 162 6 group group NN 50458 162 7 may may MD 50458 162 8 be be VB 50458 162 9 mentioned mention VBN 50458 162 10 _ _ NNP 50458 162 11 adenine adenine NN 50458 162 12 _ _ NNP 50458 162 13 , , , 50458 162 14 C{5}H{5}N{5 C{5}H{5}N{5 NNP 50458 162 15 } } -RRB- 50458 162 16 , , , 50458 162 17 which which WDT 50458 162 18 is be VBZ 50458 162 19 obtained obtain VBN 50458 162 20 from from IN 50458 162 21 infusions infusion NNS 50458 162 22 of of IN 50458 162 23 tea tea NN 50458 162 24 . . . 50458 163 1 [ [ -LRB- 50458 163 2 15 15 CD 50458 163 3 ] ] -RRB- 50458 163 4 This this DT 50458 163 5 base base NN 50458 163 6 is be VBZ 50458 163 7 non non JJ 50458 163 8 - - JJ 50458 163 9 toxic toxic JJ 50458 163 10 ; ; : 50458 163 11 it -PRON- PRP 50458 163 12 was be VBD 50458 163 13 discovered discover VBN 50458 163 14 by by IN 50458 163 15 Kossel,[16 Kossel,[16 NNP 50458 163 16 ] ] -RRB- 50458 163 17 and and CC 50458 163 18 it -PRON- PRP 50458 163 19 crystallizes crystallize VBZ 50458 163 20 easily easily RB 50458 163 21 . . . 50458 164 1 [ [ -LRB- 50458 164 2 15 15 CD 50458 164 3 ] ] -RRB- 50458 164 4 KRUGER KRUGER NNP 50458 164 5 : : : 50458 164 6 _ _ NNP 50458 164 7 Bull Bull NNP 50458 164 8 . . . 50458 165 1 Soc Soc NNP 50458 165 2 . . . 50458 166 1 Chim Chim NNP 50458 166 2 . . . 50458 166 3 _ _ NNP 50458 166 4 ( ( -LRB- 50458 166 5 3 3 CD 50458 166 6 ) ) -RRB- 50458 166 7 , , , 50458 166 8 VIII VIII NNP 50458 166 9 , , , 50458 166 10 p. p. NN 50458 166 11 687 687 CD 50458 166 12 . . . 50458 167 1 [ [ -LRB- 50458 167 2 16 16 CD 50458 167 3 ] ] -RRB- 50458 167 4 KOSSEL KOSSEL NNP 50458 167 5 : : : 50458 167 6 _ _ NNP 50458 167 7 Zeitschrift Zeitschrift NNP 50458 167 8 für für NN 50458 167 9 physiol physiol NN 50458 167 10 . . . 50458 168 1 Chim Chim NNP 50458 168 2 . . . 50458 168 3 _ _ NNP 50458 168 4 , , , 50458 168 5 X X NNP 50458 168 6 , , , 50458 168 7 p. p. NN 50458 168 8 248 248 CD 50458 168 9 ; ; : 50458 168 10 and and CC 50458 168 11 _ _ NNP 50458 168 12 Bull Bull NNP 50458 168 13 . . . 50458 169 1 Soc Soc NNP 50458 169 2 . . . 50458 170 1 Chim Chim NNP 50458 170 2 . . . 50458 170 3 _ _ NNP 50458 170 4 ( ( -LRB- 50458 170 5 3 3 CD 50458 170 6 ) ) -RRB- 50458 170 7 , , , 50458 170 8 III III NNP 50458 170 9 , , , 50458 170 10 p. p. NN 50458 170 11 239 239 CD 50458 170 12 . . . 50458 171 1 Some some DT 50458 171 2 others other NNS 50458 171 3 of of IN 50458 171 4 this this DT 50458 171 5 group group NN 50458 171 6 are be VBP 50458 171 7 : : : 50458 171 8 _ _ NNP 50458 171 9 Guanine Guanine NNP 50458 171 10 _ _ NNP 50458 171 11 , , , 50458 171 12 C{5}H{5}N{5}O C{5}H{5}N{5}O NNP 50458 171 13 , , , 50458 171 14 non non JJ 50458 171 15 - - JJ 50458 171 16 toxic toxic JJ 50458 171 17 , , , 50458 171 18 discovered discover VBN 50458 171 19 by by IN 50458 171 20 Unger Unger NNP 50458 171 21 ; ; : 50458 171 22 _ _ NNP 50458 171 23 pseudo pseudo NNP 50458 171 24 - - NNP 50458 171 25 xanthine xanthine NNP 50458 171 26 _ _ NNP 50458 171 27 , , , 50458 171 28 obtained obtain VBN 50458 171 29 from from IN 50458 171 30 muscular muscular JJ 50458 171 31 tissues tissue NNS 50458 171 32 ; ; : 50458 171 33 _ _ NNP 50458 171 34 sarcine sarcine NNP 50458 171 35 _ _ NNP 50458 171 36 , , , 50458 171 37 C{5}H{4}N{4}O C{5}H{4}N{4}O NNP 50458 171 38 , , , 50458 171 39 also also RB 50458 171 40 but but CC 50458 171 41 slightly slightly RB 50458 171 42 toxic toxic JJ 50458 171 43 , , , 50458 171 44 discovered discover VBN 50458 171 45 by by IN 50458 171 46 Scherer Scherer NNP 50458 171 47 ; ; : 50458 171 48 _ _ NNP 50458 171 49 xanthine xanthine NNP 50458 171 50 _ _ NNP 50458 171 51 , , , 50458 171 52 C{5}H{4}N{4}O{2 C{5}H{4}N{4}O{2 NNP 50458 171 53 } } -RRB- 50458 171 54 , , , 50458 171 55 which which WDT 50458 171 56 is be VBZ 50458 171 57 found find VBN 50458 171 58 in in IN 50458 171 59 many many JJ 50458 171 60 urines urine NNS 50458 171 61 , , , 50458 171 62 and and CC 50458 171 63 which which WDT 50458 171 64 acts act VBZ 50458 171 65 as as IN 50458 171 66 a a DT 50458 171 67 stimulant stimulant NN 50458 171 68 on on IN 50458 171 69 the the DT 50458 171 70 cardiac cardiac JJ 50458 171 71 muscles muscle NNS 50458 171 72 ; ; : 50458 171 73 _ _ NNP 50458 171 74 paraxanthine paraxanthine NN 50458 171 75 _ _ NNP 50458 171 76 , , , 50458 171 77 C{7}H{8}N{4}O{2 C{7}H{8}N{4}O{2 NNP 50458 171 78 } } -RRB- 50458 171 79 , , , 50458 171 80 a a DT 50458 171 81 toxic toxic JJ 50458 171 82 base base NN 50458 171 83 found find VBN 50458 171 84 in in IN 50458 171 85 certain certain JJ 50458 171 86 pathological pathological JJ 50458 171 87 urines urine NNS 50458 171 88 ; ; : 50458 171 89 _ _ NNP 50458 171 90 caffeine caffeine NN 50458 171 91 _ _ NNP 50458 171 92 and and CC 50458 171 93 _ _ NNP 50458 171 94 theobromine theobromine NN 50458 171 95 _ _ NNP 50458 171 96 , , , 50458 171 97 powerful powerful JJ 50458 171 98 diuretic diuretic JJ 50458 171 99 bases basis NNS 50458 171 100 ; ; : 50458 171 101 and and CC 50458 171 102 _ _ NNP 50458 171 103 carnine carnine NN 50458 171 104 _ _ NNP 50458 171 105 , , , 50458 171 106 C{7}H{8}N{4}O{3 C{7}H{8}N{4}O{3 NNP 50458 171 107 } } -RRB- 50458 171 108 , , , 50458 171 109 from from IN 50458 171 110 meat meat NN 50458 171 111 , , , 50458 171 112 a a DT 50458 171 113 muscular muscular JJ 50458 171 114 stimulant stimulant NN 50458 171 115 like like IN 50458 171 116 caffeine caffeine NN 50458 171 117 . . . 50458 172 1 2 2 LS 50458 172 2 . . . 50458 173 1 = = NFP 50458 173 2 Creatinic Creatinic NNP 50458 173 3 Leucomaines.=--These Leucomaines.=--These '' 50458 173 4 have have VBP 50458 173 5 for for IN 50458 173 6 their -PRON- PRP$ 50458 173 7 type type NN 50458 173 8 guanidine guanidine NN 50458 173 9 ; ; : 50458 173 10 they -PRON- PRP 50458 173 11 differ differ VBP 50458 173 12 from from IN 50458 173 13 the the DT 50458 173 14 xanthic xanthic JJ 50458 173 15 bases basis NNS 50458 173 16 in in IN 50458 173 17 that that IN 50458 173 18 they -PRON- PRP 50458 173 19 are be VBP 50458 173 20 not not RB 50458 173 21 precipitated precipitate VBN 50458 173 22 by by IN 50458 173 23 copper copper NN 50458 173 24 acetate acetate NN 50458 173 25 , , , 50458 173 26 but but CC 50458 173 27 frequently frequently RB 50458 173 28 are be VBP 50458 173 29 by by IN 50458 173 30 ammoniacal ammoniacal JJ 50458 173 31 silver silver NN 50458 173 32 nitrate nitrate JJ 50458 173 33 . . . 50458 174 1 They -PRON- PRP 50458 174 2 yield yield VBP 50458 174 3 double double JJ 50458 174 4 salts salt NNS 50458 174 5 with with IN 50458 174 6 the the DT 50458 174 7 chlorides chloride NNS 50458 174 8 of of IN 50458 174 9 zinc zinc NN 50458 174 10 and and CC 50458 174 11 cadmium cadmium NN 50458 174 12 . . . 50458 175 1 To to IN 50458 175 2 this this DT 50458 175 3 group group NN 50458 175 4 belong belong VBP 50458 175 5 _ _ NNP 50458 175 6 glycocyanine glycocyanine NN 50458 175 7 _ _ NNP 50458 175 8 , , , 50458 175 9 C{3}H{7}N{3}O{2 C{3}H{7}N{3}O{2 NNP 50458 175 10 } } -RRB- 50458 175 11 , , , 50458 175 12 and and CC 50458 175 13 _ _ NNP 50458 175 14 glycocyanidine glycocyanidine NN 50458 175 15 _ _ NNP 50458 175 16 , , , 50458 175 17 C{3}H{7}N{3}O C{3}H{7}N{3}O NNP 50458 175 18 , , , 50458 175 19 both both DT 50458 175 20 very very RB 50458 175 21 toxic toxic JJ 50458 175 22 ; ; : 50458 175 23 _ _ NNP 50458 175 24 creatine creatine NN 50458 175 25 _ _ NNP 50458 175 26 , , , 50458 175 27 C{4}H{9}N{3}O{2 C{4}H{9}N{3}O{2 NNP 50458 175 28 } } -RRB- 50458 175 29 , , , 50458 175 30 only only RB 50458 175 31 slightly slightly RB 50458 175 32 toxic toxic JJ 50458 175 33 ; ; : 50458 175 34 _ _ NNP 50458 175 35 creatinine creatinine NN 50458 175 36 _ _ NNP 50458 175 37 , , , 50458 175 38 C{4}H{7}N{3}O C{4}H{7}N{3}O NNP 50458 175 39 ; ; : 50458 175 40 _ _ NNP 50458 175 41 lysatine lysatine NN 50458 175 42 _ _ NNP 50458 175 43 , , , 50458 175 44 which which WDT 50458 175 45 very very RB 50458 175 46 easily easily RB 50458 175 47 decomposes decompose VBZ 50458 175 48 to to TO 50458 175 49 form form VB 50458 175 50 urea urea NNP 50458 175 51 ; ; : 50458 175 52 _ _ NNP 50458 175 53 lysatinine lysatinine NN 50458 175 54 _ _ NNP 50458 175 55 , , , 50458 175 56 _ _ NNP 50458 175 57 xanthocreatine xanthocreatine NNP 50458 175 58 _ _ NNP 50458 175 59 ; ; : 50458 175 60 _ _ NNP 50458 175 61 arginine arginine NNP 50458 175 62 _ _ NNP 50458 175 63 , , , 50458 175 64 a a DT 50458 175 65 vegetable vegetable NN 50458 175 66 base base NN 50458 175 67 , , , 50458 175 68 etc etc FW 50458 175 69 . . . 50458 176 1 3 3 LS 50458 176 2 . . . 50458 177 1 = = NFP 50458 177 2 Neurinic neurinic JJ 50458 177 3 Leucomaines.=--These Leucomaines.=--These `` 50458 177 4 have have VBP 50458 177 5 none none NN 50458 177 6 of of IN 50458 177 7 the the DT 50458 177 8 characteristics characteristic NNS 50458 177 9 of of IN 50458 177 10 the the DT 50458 177 11 preceding precede VBG 50458 177 12 bases basis NNS 50458 177 13 ; ; : 50458 177 14 their -PRON- PRP$ 50458 177 15 type type NN 50458 177 16 is be VBZ 50458 177 17 neurine neurine NN 50458 177 18 , , , 50458 177 19 a a DT 50458 177 20 highly highly RB 50458 177 21 toxic toxic JJ 50458 177 22 base base NN 50458 177 23 found find VBN 50458 177 24 in in IN 50458 177 25 the the DT 50458 177 26 brain brain NN 50458 177 27 , , , 50458 177 28 nerves nerve NNS 50458 177 29 , , , 50458 177 30 and and CC 50458 177 31 certain certain JJ 50458 177 32 fish fish NN 50458 177 33 ova ova NNP 50458 177 34 . . . 50458 178 1 These these DT 50458 178 2 bases basis NNS 50458 178 3 are be VBP 50458 178 4 sometimes sometimes RB 50458 178 5 normally normally RB 50458 178 6 produced produce VBN 50458 178 7 by by IN 50458 178 8 the the DT 50458 178 9 animal animal NN 50458 178 10 economy economy NN 50458 178 11 , , , 50458 178 12 and and CC 50458 178 13 are be VBP 50458 178 14 also also RB 50458 178 15 frequently frequently RB 50458 178 16 the the DT 50458 178 17 result result NN 50458 178 18 of of IN 50458 178 19 microbic microbic JJ 50458 178 20 action action NN 50458 178 21 . . . 50458 179 1 They -PRON- PRP 50458 179 2 are be VBP 50458 179 3 the the DT 50458 179 4 result result NN 50458 179 5 of of IN 50458 179 6 the the DT 50458 179 7 simple simple JJ 50458 179 8 phenomena phenomenon NNS 50458 179 9 of of IN 50458 179 10 fermentative fermentative JJ 50458 179 11 hydrolyzation hydrolyzation NN 50458 179 12 of of IN 50458 179 13 protagons protagon NNS 50458 179 14 and and CC 50458 179 15 lecithins lecithin NNS 50458 179 16 . . . 50458 180 1 Among among IN 50458 180 2 these these DT 50458 180 3 bases basis NNS 50458 180 4 are be VBP 50458 180 5 _ _ NNP 50458 180 6 choline choline NN 50458 180 7 _ _ NNP 50458 180 8 , , , 50458 180 9 a a DT 50458 180 10 weak weak JJ 50458 180 11 alkaloid alkaloid NN 50458 180 12 , , , 50458 180 13 and and CC 50458 180 14 _ _ NNP 50458 180 15 betaine betaine NN 50458 180 16 _ _ NNP 50458 180 17 , , , 50458 180 18 which which WDT 50458 180 19 appears appear VBZ 50458 180 20 to to TO 50458 180 21 be be VB 50458 180 22 non non JJ 50458 180 23 - - JJ 50458 180 24 toxic toxic JJ 50458 180 25 . . . 50458 181 1 The the DT 50458 181 2 former former JJ 50458 181 3 has have VBZ 50458 181 4 the the DT 50458 181 5 formula formula NN 50458 181 6 C{5}H{15}NO{2 C{5}H{15}NO{2 NNS 50458 181 7 } } -RRB- 50458 181 8 ; ; : 50458 181 9 it -PRON- PRP 50458 181 10 was be VBD 50458 181 11 discovered discover VBN 50458 181 12 by by IN 50458 181 13 Stocker Stocker NNP 50458 181 14 . . . 50458 182 1 Wurtz Wurtz NNP 50458 182 2 synthesized synthesize VBD 50458 182 3 it -PRON- PRP 50458 182 4 by by IN 50458 182 5 combining combine VBG 50458 182 6 trimethylamine trimethylamine NN 50458 182 7 and and CC 50458 182 8 glycol glycol NN 50458 182 9 - - HYPH 50458 182 10 monochlorhydrine monochlorhydrine NN 50458 182 11 , , , 50458 182 12 and and CC 50458 182 13 treating treat VBG 50458 182 14 the the DT 50458 182 15 resulting result VBG 50458 182 16 hydrochloride hydrochloride NN 50458 182 17 with with IN 50458 182 18 silver silver NN 50458 182 19 oxide oxide NN 50458 182 20 . . . 50458 183 1 Betaine betaine JJ 50458 183 2 , , , 50458 183 3 C{5}H{11}NO{2 C{5}H{11}NO{2 NNS 50458 183 4 } } -RRB- 50458 183 5 , , , 50458 183 6 is be VBZ 50458 183 7 found find VBN 50458 183 8 in in IN 50458 183 9 beets beet NNS 50458 183 10 ; ; : 50458 183 11 it -PRON- PRP 50458 183 12 was be VBD 50458 183 13 discovered discover VBN 50458 183 14 by by IN 50458 183 15 Scheibler Scheibler NNP 50458 183 16 . . . 50458 184 1 Neurine Neurine NNP 50458 184 2 is be VBZ 50458 184 3 , , , 50458 184 4 chemically chemically RB 50458 184 5 , , , 50458 184 6 trimethylvinylammonium trimethylvinylammonium NN 50458 184 7 hydrate hydrate NN 50458 184 8 . . . 50458 185 1 4 4 LS 50458 185 2 . . . 50458 186 1 = = NFP 50458 186 2 Undetermined Undetermined NNP 50458 186 3 Leucomaines.=--Among Leucomaines.=--Among NNP 50458 186 4 these these DT 50458 186 5 bases basis NNS 50458 186 6 several several JJ 50458 186 7 are be VBP 50458 186 8 important important JJ 50458 186 9 in in IN 50458 186 10 more more JJR 50458 186 11 than than IN 50458 186 12 one one CD 50458 186 13 respect respect NN 50458 186 14 . . . 50458 187 1 For for IN 50458 187 2 instance instance NN 50458 187 3 _ _ NNP 50458 187 4 spermine spermine NN 50458 187 5 _ _ NNP 50458 187 6 , , , 50458 187 7 which which WDT 50458 187 8 is be VBZ 50458 187 9 found find VBN 50458 187 10 in in IN 50458 187 11 the the DT 50458 187 12 sperm sperm NN 50458 187 13 , , , 50458 187 14 is be VBZ 50458 187 15 a a DT 50458 187 16 strong strong JJ 50458 187 17 base base NN 50458 187 18 possessing possess VBG 50458 187 19 a a DT 50458 187 20 powerfully powerfully RB 50458 187 21 dynamic dynamic JJ 50458 187 22 and and CC 50458 187 23 tonic tonic NN 50458 187 24 action action NN 50458 187 25 on on IN 50458 187 26 the the DT 50458 187 27 nerves nerve NNS 50458 187 28 . . . 50458 188 1 It -PRON- PRP 50458 188 2 acts act VBZ 50458 188 3 as as IN 50458 188 4 an an DT 50458 188 5 oxidizer oxidizer NN 50458 188 6 . . . 50458 189 1 Spermine Spermine NNP 50458 189 2 was be VBD 50458 189 3 first first RB 50458 189 4 obtained obtain VBN 50458 189 5 by by IN 50458 189 6 Schreiner[17 Schreiner[17 NNP 50458 189 7 ] ] -RRB- 50458 189 8 from from IN 50458 189 9 the the DT 50458 189 10 sperm sperm NN 50458 189 11 of of IN 50458 189 12 mammifers mammifer NNS 50458 189 13 in in IN 50458 189 14 which which WDT 50458 189 15 it -PRON- PRP 50458 189 16 occurs occur VBZ 50458 189 17 as as IN 50458 189 18 a a DT 50458 189 19 phosphate phosphate NN 50458 189 20 . . . 50458 190 1 It -PRON- PRP 50458 190 2 has have VBZ 50458 190 3 the the DT 50458 190 4 formula formula NN 50458 190 5 C{5}H{14}N{2 C{5}H{14}N{2 NNP 50458 190 6 } } -RRB- 50458 190 7 . . . 50458 191 1 It -PRON- PRP 50458 191 2 was be VBD 50458 191 3 physiologically physiologically RB 50458 191 4 studied study VBN 50458 191 5 by by IN 50458 191 6 Poehl Poehl NNP 50458 191 7 , , , 50458 191 8 Tarchanoff Tarchanoff NNP 50458 191 9 , , , 50458 191 10 Weljaminoff Weljaminoff NNP 50458 191 11 , , , 50458 191 12 and and CC 50458 191 13 Joffroy Joffroy NNP 50458 191 14 . . . 50458 192 1 [ [ -LRB- 50458 192 2 18 18 CD 50458 192 3 ] ] -RRB- 50458 192 4 _ _ NNP 50458 192 5 Plasmaine Plasmaine NNP 50458 192 6 _ _ NNP 50458 192 7 , , , 50458 192 8 a a DT 50458 192 9 toxic toxic JJ 50458 192 10 base base NN 50458 192 11 found find VBN 50458 192 12 in in IN 50458 192 13 the the DT 50458 192 14 blood blood NN 50458 192 15 and and CC 50458 192 16 discovered discover VBN 50458 192 17 by by IN 50458 192 18 R. R. NNP 50458 192 19 Wurtz,[19 Wurtz,[19 NNP 50458 192 20 ] ] -RRB- 50458 192 21 has have VBZ 50458 192 22 the the DT 50458 192 23 formula formula NN 50458 192 24 C{5}H{15}N{5 C{5}H{15}N{5 NNP 50458 192 25 } } -RRB- 50458 192 26 ; ; : 50458 192 27 _ _ NNP 50458 192 28 protamine protamine NN 50458 192 29 _ _ NNP 50458 192 30 , , , 50458 192 31 from from IN 50458 192 32 fish fish NN 50458 192 33 milt milt NN 50458 192 34 , , , 50458 192 35 was be VBD 50458 192 36 discovered discover VBN 50458 192 37 by by IN 50458 192 38 Micocher Micocher NNP 50458 192 39 . . . 50458 193 1 [ [ -LRB- 50458 193 2 20 20 CD 50458 193 3 ] ] -RRB- 50458 193 4 [ [ -LRB- 50458 193 5 17 17 CD 50458 193 6 ] ] -RRB- 50458 193 7 _ _ NNP 50458 193 8 Liebig Liebig NNP 50458 193 9 's 's POS 50458 193 10 Ann Ann NNP 50458 193 11 . . . 50458 194 1 der der IN 50458 194 2 Chemie Chemie NNP 50458 194 3 _ _ NNP 50458 194 4 , , , 50458 194 5 CXCIV CXCIV NNP 50458 194 6 , , , 50458 194 7 p. p. NN 50458 194 8 68 68 CD 50458 194 9 . . . 50458 195 1 [ [ -LRB- 50458 195 2 18 18 CD 50458 195 3 ] ] -RRB- 50458 195 4 _ _ NNP 50458 195 5 Journ Journ NNP 50458 195 6 . . . 50458 196 1 Soc Soc NNP 50458 196 2 . . . 50458 197 1 Phys phys NN 50458 197 2 . . . 50458 198 1 Chim chim UH 50458 198 2 . . . 50458 199 1 Russe Russe NNP 50458 199 2 _ _ NNP 50458 199 3 , , , 50458 199 4 1893 1893 CD 50458 199 5 , , , 50458 199 6 No no UH 50458 199 7 . . . 50458 200 1 2 2 LS 50458 200 2 ; ; : 50458 200 3 and and CC 50458 200 4 _ _ NNP 50458 200 5 Bull Bull NNP 50458 200 6 . . . 50458 201 1 Soc Soc NNP 50458 201 2 . . . 50458 202 1 Chim Chim NNP 50458 202 2 . . . 50458 202 3 _ _ NNP 50458 202 4 ( ( -LRB- 50458 202 5 3 3 CD 50458 202 6 ) ) -RRB- 50458 202 7 , , , 50458 202 8 XII XII NNP 50458 202 9 , , , 50458 202 10 p. p. NN 50458 202 11 243 243 CD 50458 202 12 . . . 50458 203 1 [ [ -LRB- 50458 203 2 19 19 CD 50458 203 3 ] ] -RRB- 50458 203 4 _ _ NNP 50458 203 5 Leucomaines Leucomaines NNP 50458 203 6 du du VBZ 50458 203 7 Sang Sang NNP 50458 203 8 Normal Normal NNP 50458 203 9 _ _ NNP 50458 203 10 , , , 50458 203 11 Thèse Thèse NNP 50458 203 12 , , , 50458 203 13 Paris Paris NNP 50458 203 14 , , , 50458 203 15 1889 1889 CD 50458 203 16 . . . 50458 204 1 [ [ -LRB- 50458 204 2 20 20 CD 50458 204 3 ] ] -RRB- 50458 204 4 _ _ NNP 50458 204 5 Joh Joh NNP 50458 204 6 reab reab NN 50458 204 7 . . . 50458 205 1 de de NNP 50458 205 2 Thiérchen Thiérchen NNP 50458 205 3 _ _ NNP 50458 205 4 , , , 50458 205 5 1874 1874 CD 50458 205 6 , , , 50458 205 7 p. p. NN 50458 205 8 341 341 CD 50458 205 9 ; ; : 50458 205 10 Picard Picard NNP 50458 205 11 , , , 50458 205 12 _ _ NNP 50458 205 13 Ibid Ibid NNP 50458 205 14 . . . 50458 205 15 _ _ NNP 50458 205 16 , , , 50458 205 17 p. p. NN 50458 205 18 355 355 CD 50458 205 19 . . . 50458 206 1 CHAPTER CHAPTER NNP 50458 206 2 II II NNP 50458 206 3 . . . 50458 207 1 TOXINS toxin NNS 50458 207 2 AND and CC 50458 207 3 ANTITOXINS antitoxin NNS 50458 207 4 . . . 50458 208 1 We -PRON- PRP 50458 208 2 have have VBP 50458 208 3 already already RB 50458 208 4 seen see VBN 50458 208 5 , , , 50458 208 6 in in IN 50458 208 7 the the DT 50458 208 8 preceding precede VBG 50458 208 9 chapter chapter NN 50458 208 10 , , , 50458 208 11 that that IN 50458 208 12 the the DT 50458 208 13 microbes microbe NNS 50458 208 14 and and CC 50458 208 15 the the DT 50458 208 16 cells cell NNS 50458 208 17 of of IN 50458 208 18 various various JJ 50458 208 19 organisms organism NNS 50458 208 20 are be VBP 50458 208 21 capable capable JJ 50458 208 22 of of IN 50458 208 23 secreting secrete VBG 50458 208 24 definite definite JJ 50458 208 25 products product NNS 50458 208 26 of of IN 50458 208 27 a a DT 50458 208 28 toxic toxic JJ 50458 208 29 nature nature NN 50458 208 30 to to TO 50458 208 31 which which WDT 50458 208 32 the the DT 50458 208 33 names name NNS 50458 208 34 " " `` 50458 208 35 ptomaines ptomaine NNS 50458 208 36 " " '' 50458 208 37 and and CC 50458 208 38 " " `` 50458 208 39 leucomaines leucomaine NNS 50458 208 40 " " '' 50458 208 41 have have VBP 50458 208 42 been be VBN 50458 208 43 given give VBN 50458 208 44 . . . 50458 209 1 Researches Researches NNP 50458 209 2 , , , 50458 209 3 which which WDT 50458 209 4 were be VBD 50458 209 5 begun begin VBN 50458 209 6 scarcely scarcely RB 50458 209 7 twenty twenty CD 50458 209 8 years year NNS 50458 209 9 ago ago RB 50458 209 10 , , , 50458 209 11 have have VBP 50458 209 12 shown show VBN 50458 209 13 that that IN 50458 209 14 , , , 50458 209 15 besides besides IN 50458 209 16 these these DT 50458 209 17 crystallizable crystallizable JJ 50458 209 18 and and CC 50458 209 19 definite definite JJ 50458 209 20 products product NNS 50458 209 21 , , , 50458 209 22 we -PRON- PRP 50458 209 23 meet meet VBP 50458 209 24 with with IN 50458 209 25 basic basic JJ 50458 209 26 non non JJ 50458 209 27 - - JJ 50458 209 28 crystallizable crystallizable JJ 50458 209 29 substances substance NNS 50458 209 30 of of IN 50458 209 31 unknown unknown JJ 50458 209 32 composition composition NN 50458 209 33 , , , 50458 209 34 possessing possess VBG 50458 209 35 special special JJ 50458 209 36 toxic toxic JJ 50458 209 37 properties property NNS 50458 209 38 , , , 50458 209 39 sometimes sometimes RB 50458 209 40 even even RB 50458 209 41 of of IN 50458 209 42 extreme extreme JJ 50458 209 43 violence violence NN 50458 209 44 . . . 50458 210 1 These these DT 50458 210 2 substances substance NNS 50458 210 3 have have VBP 50458 210 4 been be VBN 50458 210 5 named name VBN 50458 210 6 " " `` 50458 210 7 toxins toxin NNS 50458 210 8 . . . 50458 210 9 " " '' 50458 211 1 At at IN 50458 211 2 first first RB 50458 211 3 this this DT 50458 211 4 generic generic JJ 50458 211 5 name name NN 50458 211 6 was be VBD 50458 211 7 extended extend VBN 50458 211 8 toward toward IN 50458 211 9 indefinite indefinite JJ 50458 211 10 basic basic JJ 50458 211 11 organic organic JJ 50458 211 12 products product NNS 50458 211 13 that that WDT 50458 211 14 could could MD 50458 211 15 be be VB 50458 211 16 isolated isolate VBN 50458 211 17 from from IN 50458 211 18 tissues tissue NNS 50458 211 19 and and CC 50458 211 20 tumors tumor NNS 50458 211 21 both both CC 50458 211 22 normal normal JJ 50458 211 23 and and CC 50458 211 24 abnormal abnormal JJ 50458 211 25 ; ; : 50458 211 26 later later RB 50458 211 27 on on RB 50458 211 28 , , , 50458 211 29 however however RB 50458 211 30 , , , 50458 211 31 the the DT 50458 211 32 name name NN 50458 211 33 was be VBD 50458 211 34 applied apply VBN 50458 211 35 to to IN 50458 211 36 toxic toxic JJ 50458 211 37 substances substance NNS 50458 211 38 , , , 50458 211 39 equally equally RB 50458 211 40 indefinite indefinite JJ 50458 211 41 , , , 50458 211 42 isolated isolate VBN 50458 211 43 from from IN 50458 211 44 the the DT 50458 211 45 culture culture NN 50458 211 46 media medium NNS 50458 211 47 of of IN 50458 211 48 microbes microbe NNS 50458 211 49 and and CC 50458 211 50 the the DT 50458 211 51 active active JJ 50458 211 52 constituent constituent NN 50458 211 53 of of IN 50458 211 54 various various JJ 50458 211 55 venoms venom NNS 50458 211 56 . . . 50458 212 1 It -PRON- PRP 50458 212 2 is be VBZ 50458 212 3 only only RB 50458 212 4 since since IN 50458 212 5 1885 1885 CD 50458 212 6 , , , 50458 212 7 when when WRB 50458 212 8 Charrin Charrin NNP 50458 212 9 called call VBD 50458 212 10 attention attention NN 50458 212 11 to to IN 50458 212 12 them -PRON- PRP 50458 212 13 , , , 50458 212 14 that that IN 50458 212 15 investigations investigation NNS 50458 212 16 began begin VBD 50458 212 17 to to TO 50458 212 18 be be VB 50458 212 19 made make VBN 50458 212 20 regarding regard VBG 50458 212 21 them -PRON- PRP 50458 212 22 . . . 50458 213 1 In in IN 50458 213 2 1888 1888 CD 50458 213 3 Roux Roux NNP 50458 213 4 and and CC 50458 213 5 Yersin,[21 Yersin,[21 NNP 50458 213 6 ] ] -RRB- 50458 213 7 in in IN 50458 213 8 their -PRON- PRP$ 50458 213 9 beautiful beautiful JJ 50458 213 10 researches research NNS 50458 213 11 on on IN 50458 213 12 diphtheria diphtheria NN 50458 213 13 , , , 50458 213 14 pointed point VBD 50458 213 15 out out RP 50458 213 16 the the DT 50458 213 17 diastatic diastatic JJ 50458 213 18 nature nature NN 50458 213 19 of of IN 50458 213 20 the the DT 50458 213 21 properties property NNS 50458 213 22 of of IN 50458 213 23 the the DT 50458 213 24 active active JJ 50458 213 25 albuminoid albuminoid NN 50458 213 26 matter matter NN 50458 213 27 existing exist VBG 50458 213 28 in in IN 50458 213 29 the the DT 50458 213 30 cultures culture NNS 50458 213 31 of of IN 50458 213 32 the the DT 50458 213 33 specific specific JJ 50458 213 34 bacilli bacilli NN 50458 213 35 of of IN 50458 213 36 this this DT 50458 213 37 disease disease NN 50458 213 38 . . . 50458 214 1 From from IN 50458 214 2 that that DT 50458 214 3 period period NN 50458 214 4 , , , 50458 214 5 these these DT 50458 214 6 products product NNS 50458 214 7 began begin VBD 50458 214 8 to to TO 50458 214 9 take take VB 50458 214 10 a a DT 50458 214 11 more more JJR 50458 214 12 and and CC 50458 214 13 more more RBR 50458 214 14 prominent prominent JJ 50458 214 15 place place NN 50458 214 16 , , , 50458 214 17 from from IN 50458 214 18 year year NN 50458 214 19 to to IN 50458 214 20 year year NN 50458 214 21 , , , 50458 214 22 in in IN 50458 214 23 the the DT 50458 214 24 study study NN 50458 214 25 of of IN 50458 214 26 pathological pathological JJ 50458 214 27 affections affection NNS 50458 214 28 , , , 50458 214 29 and and CC 50458 214 30 , , , 50458 214 31 by by IN 50458 214 32 developing develop VBG 50458 214 33 the the DT 50458 214 34 knowledge knowledge NN 50458 214 35 of of IN 50458 214 36 immunity immunity NN 50458 214 37 , , , 50458 214 38 they -PRON- PRP 50458 214 39 have have VBP 50458 214 40 opened open VBN 50458 214 41 a a DT 50458 214 42 new new JJ 50458 214 43 path path NN 50458 214 44 to to IN 50458 214 45 the the DT 50458 214 46 investigations investigation NNS 50458 214 47 of of IN 50458 214 48 therapeutic therapeutic JJ 50458 214 49 technic technic NN 50458 214 50 . . . 50458 215 1 [ [ -LRB- 50458 215 2 21 21 CD 50458 215 3 ] ] -RRB- 50458 215 4 ROUX ROUX NNP 50458 215 5 and and CC 50458 215 6 YERSIN YERSIN NNP 50458 215 7 ; ; : 50458 215 8 Mémoire Mémoire NNP 50458 215 9 sur sur FW 50458 215 10 Diphtérie Diphtérie NNP 50458 215 11 . . . 50458 216 1 _ _ NNP 50458 216 2 Ann Ann NNP 50458 216 3 . . . 50458 217 1 Inst inst RB 50458 217 2 . . . 50458 218 1 Pasteur Pasteur NNP 50458 218 2 _ _ NNP 50458 218 3 , , , 50458 218 4 1888 1888 CD 50458 218 5 - - SYM 50458 218 6 1889 1889 CD 50458 218 7 . . . 50458 219 1 It -PRON- PRP 50458 219 2 is be VBZ 50458 219 3 due due JJ 50458 219 4 to to IN 50458 219 5 the the DT 50458 219 6 knowledge knowledge NN 50458 219 7 of of IN 50458 219 8 these these DT 50458 219 9 principles principle NNS 50458 219 10 that that WDT 50458 219 11 we -PRON- PRP 50458 219 12 have have VBP 50458 219 13 learned learn VBN 50458 219 14 that that IN 50458 219 15 the the DT 50458 219 16 infectious infectious JJ 50458 219 17 microbes microbe NNS 50458 219 18 , , , 50458 219 19 far far RB 50458 219 20 from from IN 50458 219 21 acting act VBG 50458 219 22 as as IN 50458 219 23 they -PRON- PRP 50458 219 24 were be VBD 50458 219 25 believed believe VBN 50458 219 26 to to TO 50458 219 27 do do VB 50458 219 28 only only RB 50458 219 29 a a DT 50458 219 30 few few JJ 50458 219 31 years year NNS 50458 219 32 ago ago RB 50458 219 33 , , , 50458 219 34 and and CC 50458 219 35 which which WDT 50458 219 36 Pasteur Pasteur NNP 50458 219 37 strongly strongly RB 50458 219 38 maintained maintain VBD 50458 219 39 to to TO 50458 219 40 be be VB 50458 219 41 by by IN 50458 219 42 vital vital JJ 50458 219 43 parasitism parasitism NN 50458 219 44 -- -- : 50458 219 45 such such JJ 50458 219 46 as as IN 50458 219 47 would would MD 50458 219 48 be be VB 50458 219 49 the the DT 50458 219 50 case case NN 50458 219 51 with with IN 50458 219 52 the the DT 50458 219 53 carbonizing carbonize VBG 50458 219 54 bacteria bacteria NNS 50458 219 55 which which WDT 50458 219 56 , , , 50458 219 57 according accord VBG 50458 219 58 to to IN 50458 219 59 Pasteur Pasteur NNP 50458 219 60 , , , 50458 219 61 act act VB 50458 219 62 by by IN 50458 219 63 diverting divert VBG 50458 219 64 the the DT 50458 219 65 oxygen oxygen NN 50458 219 66 , , , 50458 219 67 or or CC 50458 219 68 causing cause VBG 50458 219 69 capillary capillary JJ 50458 219 70 embolisms embolism NNS 50458 219 71 -- -- : 50458 219 72 owe owe VBP 50458 219 73 their -PRON- PRP$ 50458 219 74 pathogenic pathogenic JJ 50458 219 75 action action NN 50458 219 76 to to IN 50458 219 77 the the DT 50458 219 78 toxic toxic JJ 50458 219 79 substances substance NNS 50458 219 80 which which WDT 50458 219 81 are be VBP 50458 219 82 the the DT 50458 219 83 products product NNS 50458 219 84 of of IN 50458 219 85 their -PRON- PRP$ 50458 219 86 secretion secretion NN 50458 219 87 , , , 50458 219 88 and and CC 50458 219 89 which which WDT 50458 219 90 spread spread VBD 50458 219 91 throughout throughout IN 50458 219 92 the the DT 50458 219 93 organism organism NN 50458 219 94 , , , 50458 219 95 even even RB 50458 219 96 though though IN 50458 219 97 the the DT 50458 219 98 microbe microbe NN 50458 219 99 frequently frequently RB 50458 219 100 is be VBZ 50458 219 101 localized localize VBN 50458 219 102 in in IN 50458 219 103 a a DT 50458 219 104 very very RB 50458 219 105 circumscribed circumscribe VBN 50458 219 106 spot spot NN 50458 219 107 , , , 50458 219 108 as as IN 50458 219 109 in in IN 50458 219 110 tetanus tetanus NN 50458 219 111 and and CC 50458 219 112 in in IN 50458 219 113 diphtheria diphtheria NN 50458 219 114 . . . 50458 220 1 The the DT 50458 220 2 idea idea NN 50458 220 3 of of IN 50458 220 4 intoxication intoxication NN 50458 220 5 by by IN 50458 220 6 these these DT 50458 220 7 products product NNS 50458 220 8 has have VBZ 50458 220 9 now now RB 50458 220 10 replaced replace VBN 50458 220 11 the the DT 50458 220 12 idea idea NN 50458 220 13 of of IN 50458 220 14 the the DT 50458 220 15 direct direct JJ 50458 220 16 action action NN 50458 220 17 of of IN 50458 220 18 the the DT 50458 220 19 microbe microbe NN 50458 220 20 on on IN 50458 220 21 the the DT 50458 220 22 elements element NNS 50458 220 23 or or CC 50458 220 24 the the DT 50458 220 25 liquids liquid NNS 50458 220 26 of of IN 50458 220 27 the the DT 50458 220 28 organism organism NN 50458 220 29 . . . 50458 221 1 The the DT 50458 221 2 occurrence occurrence NN 50458 221 3 that that WDT 50458 221 4 takes take VBZ 50458 221 5 place place NN 50458 221 6 in in IN 50458 221 7 diphtheria diphtheria NN 50458 221 8 and and CC 50458 221 9 tetanus tetanus NN 50458 221 10 is be VBZ 50458 221 11 one one CD 50458 221 12 of of IN 50458 221 13 the the DT 50458 221 14 best good JJS 50458 221 15 examples example NNS 50458 221 16 to to TO 50458 221 17 cite cite VB 50458 221 18 in in IN 50458 221 19 support support NN 50458 221 20 of of IN 50458 221 21 this this DT 50458 221 22 view view NN 50458 221 23 . . . 50458 222 1 Here here RB 50458 222 2 , , , 50458 222 3 in in IN 50458 222 4 fact fact NN 50458 222 5 , , , 50458 222 6 the the DT 50458 222 7 pathogenic pathogenic JJ 50458 222 8 microbe microbe NN 50458 222 9 is be VBZ 50458 222 10 found find VBN 50458 222 11 only only RB 50458 222 12 in in IN 50458 222 13 a a DT 50458 222 14 very very RB 50458 222 15 limited limited JJ 50458 222 16 area area NN 50458 222 17 in in IN 50458 222 18 the the DT 50458 222 19 organism organism NN 50458 222 20 attacked attack VBD 50458 222 21 -- -- : 50458 222 22 the the DT 50458 222 23 false false JJ 50458 222 24 membrane membrane NN 50458 222 25 , , , 50458 222 26 in in IN 50458 222 27 the the DT 50458 222 28 case case NN 50458 222 29 of of IN 50458 222 30 diphtheria diphtheria NN 50458 222 31 , , , 50458 222 32 or or CC 50458 222 33 frequently frequently RB 50458 222 34 only only RB 50458 222 35 a a DT 50458 222 36 slight slight JJ 50458 222 37 wound wound NN 50458 222 38 in in IN 50458 222 39 the the DT 50458 222 40 case case NN 50458 222 41 of of IN 50458 222 42 tetanus tetanus NN 50458 222 43 , , , 50458 222 44 and and CC 50458 222 45 the the DT 50458 222 46 microbe microbe NN 50458 222 47 becomes become VBZ 50458 222 48 localized localize VBN 50458 222 49 there there RB 50458 222 50 only only RB 50458 222 51 . . . 50458 223 1 Now now RB 50458 223 2 , , , 50458 223 3 in in IN 50458 223 4 both both DT 50458 223 5 cases case NNS 50458 223 6 , , , 50458 223 7 there there EX 50458 223 8 are be VBP 50458 223 9 general general JJ 50458 223 10 phenomena phenomenon NNS 50458 223 11 of of IN 50458 223 12 toxic toxic JJ 50458 223 13 effects effect NNS 50458 223 14 . . . 50458 224 1 There there EX 50458 224 2 must must MD 50458 224 3 hence hence RB 50458 224 4 be be VB 50458 224 5 a a DT 50458 224 6 diffusion diffusion NN 50458 224 7 of of IN 50458 224 8 toxic toxic JJ 50458 224 9 substances substance NNS 50458 224 10 which which WDT 50458 224 11 , , , 50458 224 12 distributed distribute VBN 50458 224 13 by by IN 50458 224 14 the the DT 50458 224 15 blood blood NN 50458 224 16 , , , 50458 224 17 affect affect VB 50458 224 18 the the DT 50458 224 19 different different JJ 50458 224 20 systems system NNS 50458 224 21 and and CC 50458 224 22 exert exert VB 50458 224 23 a a DT 50458 224 24 toxic toxic JJ 50458 224 25 action action NN 50458 224 26 on on IN 50458 224 27 the the DT 50458 224 28 entire entire JJ 50458 224 29 organism organism NN 50458 224 30 . . . 50458 225 1 It -PRON- PRP 50458 225 2 must must MD 50458 225 3 be be VB 50458 225 4 observed observe VBN 50458 225 5 that that IN 50458 225 6 the the DT 50458 225 7 toxins toxin NNS 50458 225 8 act act VBP 50458 225 9 as as IN 50458 225 10 toxic toxic JJ 50458 225 11 agents agent NNS 50458 225 12 only only RB 50458 225 13 when when WRB 50458 225 14 in in IN 50458 225 15 a a DT 50458 225 16 condition condition NN 50458 225 17 to to TO 50458 225 18 be be VB 50458 225 19 introduced introduce VBN 50458 225 20 into into IN 50458 225 21 the the DT 50458 225 22 circulation circulation NN 50458 225 23 subcutaneously subcutaneously RB 50458 225 24 . . . 50458 226 1 The the DT 50458 226 2 cause cause NN 50458 226 3 of of IN 50458 226 4 this this DT 50458 226 5 innocuousness innocuousness NN 50458 226 6 of of IN 50458 226 7 the the DT 50458 226 8 toxins toxin NNS 50458 226 9 when when WRB 50458 226 10 given give VBN 50458 226 11 per per IN 50458 226 12 os os NNP 50458 226 13 has have VBZ 50458 226 14 frequently frequently RB 50458 226 15 been be VBN 50458 226 16 studied study VBN 50458 226 17 . . . 50458 227 1 It -PRON- PRP 50458 227 2 appears appear VBZ 50458 227 3 to to TO 50458 227 4 be be VB 50458 227 5 quite quite RB 50458 227 6 probable probable JJ 50458 227 7 that that IN 50458 227 8 the the DT 50458 227 9 cause cause NN 50458 227 10 of of IN 50458 227 11 the the DT 50458 227 12 attenuation attenuation NN 50458 227 13 of of IN 50458 227 14 the the DT 50458 227 15 morbid morbid NN 50458 227 16 properties property NNS 50458 227 17 is be VBZ 50458 227 18 due due JJ 50458 227 19 to to IN 50458 227 20 the the DT 50458 227 21 intervention intervention NN 50458 227 22 of of IN 50458 227 23 the the DT 50458 227 24 digestive digestive JJ 50458 227 25 microbes microbe NNS 50458 227 26 . . . 50458 228 1 Such such JJ 50458 228 2 is be VBZ 50458 228 3 the the DT 50458 228 4 opinion opinion NN 50458 228 5 of of IN 50458 228 6 Levaditi Levaditi NNP 50458 228 7 and and CC 50458 228 8 Charrin[22 charrin[22 ADD 50458 228 9 ] ] -RRB- 50458 228 10 ; ; : 50458 228 11 it -PRON- PRP 50458 228 12 is be VBZ 50458 228 13 also also RB 50458 228 14 the the DT 50458 228 15 conclusion conclusion NN 50458 228 16 that that WDT 50458 228 17 is be VBZ 50458 228 18 to to TO 50458 228 19 be be VB 50458 228 20 drawn draw VBN 50458 228 21 from from IN 50458 228 22 the the DT 50458 228 23 experiments experiment NNS 50458 228 24 of of IN 50458 228 25 Mme Mme NNP 50458 228 26 . . . 50458 229 1 Metchnikoff metchnikoff RB 50458 229 2 and and CC 50458 229 3 of of IN 50458 229 4 Calmette[23 Calmette[23 NNS 50458 229 5 ] ] -RRB- 50458 229 6 on on IN 50458 229 7 the the DT 50458 229 8 modifications modification NNS 50458 229 9 undergone undergo VBN 50458 229 10 by by IN 50458 229 11 a a DT 50458 229 12 vegetable vegetable JJ 50458 229 13 toxalbumin toxalbumin NN 50458 229 14 , , , 50458 229 15 abrin abrin NNP 50458 229 16 , , , 50458 229 17 and and CC 50458 229 18 by by IN 50458 229 19 serpent serpent JJ 50458 229 20 venoms venom NNS 50458 229 21 , , , 50458 229 22 when when WRB 50458 229 23 these these DT 50458 229 24 toxalbumins toxalbumin NNS 50458 229 25 are be VBP 50458 229 26 inoculated inoculate VBN 50458 229 27 with with IN 50458 229 28 the the DT 50458 229 29 bacillus bacillus NN 50458 229 30 subtilis subtili VBZ 50458 229 31 chromogenus chromogenus NN 50458 229 32 . . . 50458 230 1 Moreover moreover RB 50458 230 2 , , , 50458 230 3 Charrin Charrin NNP 50458 230 4 and and CC 50458 230 5 Lefèvre,[24 Lefèvre,[24 NNP 50458 230 6 ] ] -RRB- 50458 230 7 on on IN 50458 230 8 the the DT 50458 230 9 one one CD 50458 230 10 hand hand NN 50458 230 11 , , , 50458 230 12 and and CC 50458 230 13 Nencki Nencki NNP 50458 230 14 , , , 50458 230 15 Sieber Sieber NNP 50458 230 16 and and CC 50458 230 17 Somanowsky,[25 Somanowsky,[25 NNP 50458 230 18 ] ] -RRB- 50458 230 19 and and CC 50458 230 20 Carrière,[26 carrière,[26 NN 50458 230 21 ] ] -RRB- 50458 230 22 on on IN 50458 230 23 the the DT 50458 230 24 other other JJ 50458 230 25 hand hand NN 50458 230 26 , , , 50458 230 27 have have VBP 50458 230 28 discovered discover VBN 50458 230 29 that that IN 50458 230 30 the the DT 50458 230 31 digestive digestive JJ 50458 230 32 ferments ferment NNS 50458 230 33 , , , 50458 230 34 particularly particularly RB 50458 230 35 trypsin trypsin NNP 50458 230 36 , , , 50458 230 37 destroy destroy VB 50458 230 38 , , , 50458 230 39 even even RB 50458 230 40 though though IN 50458 230 41 but but CC 50458 230 42 little little JJ 50458 230 43 , , , 50458 230 44 the the DT 50458 230 45 toxins toxin NNS 50458 230 46 secreted secrete VBN 50458 230 47 by by IN 50458 230 48 the the DT 50458 230 49 Loeffler Loeffler NNP 50458 230 50 and and CC 50458 230 51 Nicolaier Nicolaier NNP 50458 230 52 bacilli bacilli NNP 50458 230 53 . . . 50458 231 1 This this DT 50458 231 2 is be VBZ 50458 231 3 practically practically RB 50458 231 4 contrary contrary JJ 50458 231 5 to to IN 50458 231 6 the the DT 50458 231 7 opinion opinion NN 50458 231 8 of of IN 50458 231 9 Behring Behring NNP 50458 231 10 and and CC 50458 231 11 of of IN 50458 231 12 Rauson,[27 Rauson,[27 NNS 50458 231 13 ] ] -RRB- 50458 231 14 according accord VBG 50458 231 15 to to IN 50458 231 16 which which WDT 50458 231 17 the the DT 50458 231 18 innocuousness innocuousness NN 50458 231 19 of of IN 50458 231 20 the the DT 50458 231 21 microbial microbial JJ 50458 231 22 poisons poison NNS 50458 231 23 when when WRB 50458 231 24 administered administer VBN 50458 231 25 per per IN 50458 231 26 os os NNP 50458 231 27 is be VBZ 50458 231 28 due due JJ 50458 231 29 exclusively exclusively RB 50458 231 30 to to IN 50458 231 31 the the DT 50458 231 32 lack lack NN 50458 231 33 of of IN 50458 231 34 absorption absorption NN 50458 231 35 . . . 50458 232 1 [ [ -LRB- 50458 232 2 22 22 CD 50458 232 3 ] ] -RRB- 50458 232 4 CHARRIN charrin NN 50458 232 5 and and CC 50458 232 6 LEVADITI levaditi NN 50458 232 7 : : : 50458 232 8 Le Le NNP 50458 232 9 sort sort RB 50458 232 10 de de NNP 50458 232 11 toxines toxines NNP 50458 232 12 introduites introduite VBZ 50458 232 13 dans dan NNS 50458 232 14 le le NNP 50458 232 15 tube tube NN 50458 232 16 digestif digestif NN 50458 232 17 . . . 50458 233 1 _ _ NNP 50458 233 2 Journal Journal NNP 50458 233 3 de de NNP 50458 233 4 Physiologie Physiologie NNP 50458 233 5 et et NNP 50458 233 6 de de NNP 50458 233 7 Pathologie Pathologie NNP 50458 233 8 Générales Générales NNP 50458 233 9 _ _ NNP 50458 233 10 , , , 50458 233 11 1898 1898 CD 50458 233 12 , , , 50458 233 13 p. p. NN 50458 233 14 226 226 CD 50458 233 15 . . . 50458 234 1 [ [ -LRB- 50458 234 2 23 23 CD 50458 234 3 ] ] -RRB- 50458 234 4 Citing cite VBG 50458 234 5 Metchnikoff Metchnikoff NNP 50458 234 6 . . . 50458 235 1 [ [ -LRB- 50458 235 2 24 24 CD 50458 235 3 ] ] -RRB- 50458 235 4 _ _ NNP 50458 235 5 C. C. NNP 50458 236 1 rend rend VB 50458 236 2 . . . 50458 237 1 de de NNP 50458 237 2 la la NNP 50458 237 3 Soc Soc NNP 50458 237 4 . . . 50458 238 1 de de NNP 50458 238 2 Biologie Biologie NNP 50458 238 3 _ _ NNP 50458 238 4 , , , 50458 238 5 1898 1898 CD 50458 238 6 . . . 50458 239 1 [ [ -LRB- 50458 239 2 25 25 CD 50458 239 3 ] ] -RRB- 50458 239 4 _ _ NNP 50458 239 5 Centralblatt Centralblatt NNP 50458 239 6 für für NN 50458 239 7 Bakt Bakt NNP 50458 239 8 . . . 50458 239 9 _ _ NNP 50458 239 10 , , , 50458 239 11 1898 1898 CD 50458 239 12 . . . 50458 240 1 [ [ -LRB- 50458 240 2 26 26 CD 50458 240 3 ] ] -RRB- 50458 240 4 _ _ NNP 50458 240 5 C. C. NNP 50458 241 1 rend rend VB 50458 241 2 . . . 50458 242 1 de de NNP 50458 242 2 la la NNP 50458 242 3 Soc Soc NNP 50458 242 4 . . . 50458 243 1 de de NNP 50458 243 2 Biologie Biologie NNP 50458 243 3 _ _ NNP 50458 243 4 , , , 50458 243 5 1899 1899 CD 50458 243 6 . . . 50458 244 1 [ [ -LRB- 50458 244 2 27 27 CD 50458 244 3 ] ] -RRB- 50458 244 4 _ _ NNP 50458 244 5 Deutsche Deutsche NNP 50458 244 6 Med Med NNP 50458 244 7 . . . 50458 245 1 Wochenschr Wochenschr NNP 50458 245 2 . . . 50458 245 3 _ _ NNP 50458 245 4 , , , 50458 245 5 1898 1898 CD 50458 245 6 , , , 50458 245 7 No no UH 50458 245 8 . . . 50458 246 1 8 8 LS 50458 246 2 . . . 50458 247 1 = = NFP 50458 247 2 Nature nature NN 50458 247 3 of of IN 50458 247 4 the the DT 50458 247 5 Toxins.=--The toxins.=--the JJ 50458 247 6 molecules molecule NNS 50458 247 7 of of IN 50458 247 8 the the DT 50458 247 9 toxins toxin NNS 50458 247 10 are be VBP 50458 247 11 very very RB 50458 247 12 nearly nearly RB 50458 247 13 like like IN 50458 247 14 those those DT 50458 247 15 of of IN 50458 247 16 the the DT 50458 247 17 diastases diastasis NNS 50458 247 18 . . . 50458 248 1 Like like IN 50458 248 2 these these DT 50458 248 3 , , , 50458 248 4 the the DT 50458 248 5 toxins toxin NNS 50458 248 6 appear appear VBP 50458 248 7 to to TO 50458 248 8 have have VB 50458 248 9 a a DT 50458 248 10 very very RB 50458 248 11 complex complex JJ 50458 248 12 , , , 50458 248 13 and and CC 50458 248 14 very very RB 50458 248 15 unstable unstable JJ 50458 248 16 , , , 50458 248 17 internal internal JJ 50458 248 18 structure structure NN 50458 248 19 . . . 50458 249 1 Their -PRON- PRP$ 50458 249 2 mode mode NN 50458 249 3 of of IN 50458 249 4 action action NN 50458 249 5 frequently frequently RB 50458 249 6 depends depend VBZ 50458 249 7 , , , 50458 249 8 as as IN 50458 249 9 in in IN 50458 249 10 the the DT 50458 249 11 case case NN 50458 249 12 of of IN 50458 249 13 the the DT 50458 249 14 diastases diastasis NNS 50458 249 15 , , , 50458 249 16 upon upon IN 50458 249 17 the the DT 50458 249 18 medium medium NN 50458 249 19 in in IN 50458 249 20 which which WDT 50458 249 21 they -PRON- PRP 50458 249 22 occur occur VBP 50458 249 23 . . . 50458 250 1 Again again RB 50458 250 2 , , , 50458 250 3 like like IN 50458 250 4 the the DT 50458 250 5 diastases diastasis NNS 50458 250 6 , , , 50458 250 7 they -PRON- PRP 50458 250 8 are be VBP 50458 250 9 generally generally RB 50458 250 10 destroyed destroy VBN 50458 250 11 by by IN 50458 250 12 the the DT 50458 250 13 action action NN 50458 250 14 of of IN 50458 250 15 sufficiently sufficiently RB 50458 250 16 prolonged prolong VBN 50458 250 17 heat heat NN 50458 250 18 , , , 50458 250 19 but but CC 50458 250 20 less less RBR 50458 250 21 easily easily RB 50458 250 22 , , , 50458 250 23 for for IN 50458 250 24 there there EX 50458 250 25 are be VBP 50458 250 26 certain certain JJ 50458 250 27 toxins toxin NNS 50458 250 28 that that WDT 50458 250 29 resist resist VBP 50458 250 30 a a DT 50458 250 31 temperature temperature NN 50458 250 32 of of IN 50458 250 33 100 100 CD 50458 250 34 ° ° , 50458 250 35 C. C. NNP 50458 250 36 for for IN 50458 250 37 an an DT 50458 250 38 indefinite indefinite JJ 50458 250 39 period period NN 50458 250 40 . . . 50458 251 1 They -PRON- PRP 50458 251 2 are be VBP 50458 251 3 , , , 50458 251 4 like like IN 50458 251 5 the the DT 50458 251 6 diastatic diastatic JJ 50458 251 7 albuminoids albuminoid NNS 50458 251 8 , , , 50458 251 9 insoluble insoluble JJ 50458 251 10 in in IN 50458 251 11 strong strong JJ 50458 251 12 alcohol alcohol NN 50458 251 13 , , , 50458 251 14 and and CC 50458 251 15 are be VBP 50458 251 16 precipitated precipitate VBN 50458 251 17 from from IN 50458 251 18 their -PRON- PRP$ 50458 251 19 solutions solution NNS 50458 251 20 on on IN 50458 251 21 the the DT 50458 251 22 addition addition NN 50458 251 23 of of IN 50458 251 24 this this DT 50458 251 25 reagent reagent NN 50458 251 26 . . . 50458 252 1 They -PRON- PRP 50458 252 2 easily easily RB 50458 252 3 adhere adhere VBP 50458 252 4 to to IN 50458 252 5 precipitates precipitate NNS 50458 252 6 that that DT 50458 252 7 form form NN 50458 252 8 in in IN 50458 252 9 liquids liquid NNS 50458 252 10 in in IN 50458 252 11 which which WDT 50458 252 12 they -PRON- PRP 50458 252 13 occur occur VBP 50458 252 14 in in IN 50458 252 15 solution solution NN 50458 252 16 , , , 50458 252 17 and and CC 50458 252 18 possess possess VB 50458 252 19 the the DT 50458 252 20 remarkable remarkable JJ 50458 252 21 property property NN 50458 252 22 of of IN 50458 252 23 diastases diastasis NNS 50458 252 24 in in IN 50458 252 25 that that DT 50458 252 26 imponderable imponderable JJ 50458 252 27 masses masse NNS 50458 252 28 produce produce VBP 50458 252 29 considerable considerable JJ 50458 252 30 results result NNS 50458 252 31 . . . 50458 253 1 [ [ -LRB- 50458 253 2 28 28 CD 50458 253 3 ] ] -RRB- 50458 253 4 [ [ -LRB- 50458 253 5 28 28 CD 50458 253 6 ] ] -RRB- 50458 253 7 See see VB 50458 253 8 POZZI POZZI NNP 50458 253 9 - - HYPH 50458 253 10 ESCOT ESCOT NNP 50458 253 11 : : : 50458 253 12 Les Les NNP 50458 253 13 diastases diastase VBZ 50458 253 14 et et NN 50458 253 15 leurs leurs NN 50458 253 16 applications application NNS 50458 253 17 , , , 50458 253 18 published publish VBN 50458 253 19 by by IN 50458 253 20 Masson Masson NNP 50458 253 21 , , , 50458 253 22 1900 1900 CD 50458 253 23 ; ; : 50458 253 24 and and CC 50458 253 25 _ _ NNP 50458 253 26 Traité Traité NNP 50458 253 27 de de NNP 50458 253 28 Physico Physico NNP 50458 253 29 - - HYPH 50458 253 30 chimie chimie NNP 50458 253 31 _ _ NNP 50458 253 32 . . . 50458 254 1 Although although IN 50458 254 2 closely closely RB 50458 254 3 allied ally VBN 50458 254 4 to to IN 50458 254 5 certain certain JJ 50458 254 6 alkaloidal alkaloidal NN 50458 254 7 bases basis NNS 50458 254 8 , , , 50458 254 9 the the DT 50458 254 10 toxins toxin NNS 50458 254 11 are be VBP 50458 254 12 sharply sharply RB 50458 254 13 distinguished distinguish VBN 50458 254 14 by by IN 50458 254 15 the the DT 50458 254 16 remarkable remarkable JJ 50458 254 17 fact fact NN 50458 254 18 that that IN 50458 254 19 their -PRON- PRP$ 50458 254 20 action action NN 50458 254 21 is be VBZ 50458 254 22 never never RB 50458 254 23 immediate immediate JJ 50458 254 24 , , , 50458 254 25 but but CC 50458 254 26 is be VBZ 50458 254 27 always always RB 50458 254 28 preceded precede VBN 50458 254 29 by by IN 50458 254 30 a a DT 50458 254 31 period period NN 50458 254 32 of of IN 50458 254 33 incubation incubation NN 50458 254 34 , , , 50458 254 35 which which WDT 50458 254 36 may may MD 50458 254 37 be be VB 50458 254 38 quite quite RB 50458 254 39 long long JJ 50458 254 40 . . . 50458 255 1 Like like IN 50458 255 2 the the DT 50458 255 3 alkaloidal alkaloidal NN 50458 255 4 bases basis NNS 50458 255 5 , , , 50458 255 6 they -PRON- PRP 50458 255 7 appear appear VBP 50458 255 8 to to TO 50458 255 9 result result VB 50458 255 10 from from IN 50458 255 11 the the DT 50458 255 12 hydrolyzing hydrolyzing NN 50458 255 13 breaking break VBG 50458 255 14 down down RP 50458 255 15 of of IN 50458 255 16 albuminoids albuminoid NNS 50458 255 17 and and CC 50458 255 18 nucleo nucleo NNP 50458 255 19 - - HYPH 50458 255 20 albumins albumin NNS 50458 255 21 , , , 50458 255 22 and and CC 50458 255 23 they -PRON- PRP 50458 255 24 appear appear VBP 50458 255 25 to to TO 50458 255 26 be be VB 50458 255 27 intermediary intermediary JJ 50458 255 28 , , , 50458 255 29 from from IN 50458 255 30 a a DT 50458 255 31 chemical chemical NN 50458 255 32 point point NN 50458 255 33 of of IN 50458 255 34 view view NN 50458 255 35 , , , 50458 255 36 between between IN 50458 255 37 these these DT 50458 255 38 bodies body NNS 50458 255 39 , , , 50458 255 40 the the DT 50458 255 41 general general JJ 50458 255 42 characters character NNS 50458 255 43 of of IN 50458 255 44 which which WDT 50458 255 45 they -PRON- PRP 50458 255 46 retain retain VBP 50458 255 47 , , , 50458 255 48 and and CC 50458 255 49 the the DT 50458 255 50 alkaloids alkaloid NNS 50458 255 51 proper proper JJ 50458 255 52 , , , 50458 255 53 or or CC 50458 255 54 ptomaines ptomaine NNS 50458 255 55 , , , 50458 255 56 to to TO 50458 255 57 which which WDT 50458 255 58 we -PRON- PRP 50458 255 59 have have VBP 50458 255 60 called call VBN 50458 255 61 attention attention NN 50458 255 62 , , , 50458 255 63 and and CC 50458 255 64 the the DT 50458 255 65 principal principal JJ 50458 255 66 chemical chemical NN 50458 255 67 and and CC 50458 255 68 physiological physiological JJ 50458 255 69 properties property NNS 50458 255 70 of of IN 50458 255 71 which which WDT 50458 255 72 they -PRON- PRP 50458 255 73 possess possess VBP 50458 255 74 . . . 50458 256 1 No no DT 50458 256 2 absolutely absolutely RB 50458 256 3 precise precise JJ 50458 256 4 knowledge knowledge NN 50458 256 5 is be VBZ 50458 256 6 had have VBN 50458 256 7 regarding regard VBG 50458 256 8 the the DT 50458 256 9 chemical chemical NN 50458 256 10 nature nature NN 50458 256 11 and and CC 50458 256 12 constitution constitution NN 50458 256 13 of of IN 50458 256 14 these these DT 50458 256 15 remarkable remarkable JJ 50458 256 16 substances substance NNS 50458 256 17 . . . 50458 257 1 A a DT 50458 257 2 number number NN 50458 257 3 of of IN 50458 257 4 analyses analysis NNS 50458 257 5 of of IN 50458 257 6 these these DT 50458 257 7 substances substance NNS 50458 257 8 have have VBP 50458 257 9 been be VBN 50458 257 10 published publish VBN 50458 257 11 which which WDT 50458 257 12 , , , 50458 257 13 in in IN 50458 257 14 general general JJ 50458 257 15 , , , 50458 257 16 permit permit VB 50458 257 17 no no DT 50458 257 18 definite definite JJ 50458 257 19 conclusion conclusion NN 50458 257 20 to to TO 50458 257 21 be be VB 50458 257 22 drawn draw VBN 50458 257 23 . . . 50458 258 1 [ [ -LRB- 50458 258 2 29 29 CD 50458 258 3 ] ] -RRB- 50458 258 4 I -PRON- PRP 50458 258 5 have have VBP 50458 258 6 , , , 50458 258 7 however however RB 50458 258 8 , , , 50458 258 9 elaborated elaborate VBD 50458 258 10 several several JJ 50458 258 11 speculative speculative JJ 50458 258 12 ideas idea NNS 50458 258 13 regarding regard VBG 50458 258 14 this this DT 50458 258 15 subject subject NN 50458 258 16 . . . 50458 259 1 [ [ -LRB- 50458 259 2 30 30 CD 50458 259 3 ] ] -RRB- 50458 259 4 [ [ -LRB- 50458 259 5 29 29 CD 50458 259 6 ] ] -RRB- 50458 259 7 Regarding regard VBG 50458 259 8 this this DT 50458 259 9 see see VB 50458 259 10 the the DT 50458 259 11 works work NNS 50458 259 12 by by IN 50458 259 13 KOCH KOCH NNP 50458 259 14 and and CC 50458 259 15 BRIEGER BRIEGER NNP 50458 259 16 , , , 50458 259 17 _ _ NNP 50458 259 18 Deutsche Deutsche NNP 50458 259 19 Medicin Medicin NNP 50458 259 20 . . . 50458 260 1 Wochenschr Wochenschr NNP 50458 260 2 . . . 50458 260 3 _ _ NNP 50458 260 4 , , , 50458 260 5 Oct. October NNP 50458 260 6 22 22 CD 50458 260 7 , , , 50458 260 8 1891 1891 CD 50458 260 9 . . . 50458 261 1 [ [ -LRB- 50458 261 2 30 30 CD 50458 261 3 ] ] -RRB- 50458 261 4 POZZI POZZI NNP 50458 261 5 - - HYPH 50458 261 6 ESCOT ESCOT NNP 50458 261 7 : : : 50458 261 8 Nature nature NN 50458 261 9 des des NNP 50458 261 10 Diastases diastasis NNS 50458 261 11 . . . 50458 262 1 Published publish VBN 50458 262 2 by by IN 50458 262 3 J. J. NNP 50458 262 4 Rousset Rousset NNP 50458 262 5 , , , 50458 262 6 Paris Paris NNP 50458 262 7 , , , 50458 262 8 1903 1903 CD 50458 262 9 . . . 50458 263 1 See see VB 50458 263 2 also also RB 50458 263 3 Recherches Recherches NNP 50458 263 4 de de IN 50458 263 5 la la NNP 50458 263 6 Nature Nature NNP 50458 263 7 Chimique Chimique NNP 50458 263 8 des des NNP 50458 263 9 Diastases Diastases NNP 50458 263 10 Oxydantes Oxydantes NNPS 50458 263 11 . . . 50458 264 1 _ _ NNP 50458 264 2 Revue Revue NNP 50458 264 3 génér génér NN 50458 264 4 . . . 50458 265 1 de de NNP 50458 265 2 chimie chimie NNP 50458 265 3 _ _ NNP 50458 265 4 , , , 50458 265 5 VII VII NNP 50458 265 6 , , , 50458 265 7 pp pp NNP 50458 265 8 . . . 50458 266 1 129 129 CD 50458 266 2 - - SYM 50458 266 3 136 136 CD 50458 266 4 ; ; : 50458 266 5 and and CC 50458 266 6 Aperçus Aperçus NNP 50458 266 7 sur sur FW 50458 266 8 la la FW 50458 266 9 nature nature NN 50458 266 10 chimique chimique NN 50458 266 11 des des NNP 50458 266 12 Diastases Diastases NNP 50458 266 13 , , , 50458 266 14 _ _ NNP 50458 266 15 Bulletin Bulletin NNP 50458 266 16 de de IN 50458 266 17 l'Association l'Association NNP 50458 266 18 de de NNP 50458 266 19 Chimistes Chimistes NNP 50458 266 20 _ _ NNP 50458 266 21 , , , 50458 266 22 1904 1904 CD 50458 266 23 , , , 50458 266 24 p. p. NN 50458 267 1 769.--Propriétés 769.--propriétés ADD 50458 267 2 Catalytiques Catalytiques NNP 50458 267 3 de de IN 50458 267 4 Quelques Quelques NNP 50458 267 5 Diastases Diastases NNP 50458 267 6 ; ; : 50458 267 7 _ _ NNP 50458 267 8 Ibid Ibid NNP 50458 267 9 . . . 50458 267 10 _ _ NNP 50458 267 11 , , , 50458 267 12 1904 1904 CD 50458 267 13 , , , 50458 267 14 p. p. NN 50458 267 15 1247 1247 CD 50458 267 16 . . . 50458 268 1 We -PRON- PRP 50458 268 2 must must MD 50458 268 3 here here RB 50458 268 4 call call VB 50458 268 5 particular particular JJ 50458 268 6 attention attention NN 50458 268 7 to to IN 50458 268 8 the the DT 50458 268 9 ideas idea NNS 50458 268 10 of of IN 50458 268 11 Ehrlich Ehrlich NNP 50458 268 12 regarding regard VBG 50458 268 13 the the DT 50458 268 14 constitution constitution NN 50458 268 15 of of IN 50458 268 16 the the DT 50458 268 17 toxins toxin NNS 50458 268 18 . . . 50458 269 1 According accord VBG 50458 269 2 to to IN 50458 269 3 this this DT 50458 269 4 scientist scientist NN 50458 269 5 , , , 50458 269 6 their -PRON- PRP$ 50458 269 7 molecules molecule NNS 50458 269 8 contain contain VBP 50458 269 9 two two CD 50458 269 10 functional functional JJ 50458 269 11 groups group NNS 50458 269 12 ; ; : 50458 269 13 the the DT 50458 269 14 one one NN 50458 269 15 , , , 50458 269 16 to to TO 50458 269 17 which which WDT 50458 269 18 he -PRON- PRP 50458 269 19 has have VBZ 50458 269 20 given give VBN 50458 269 21 the the DT 50458 269 22 name name NN 50458 269 23 " " `` 50458 269 24 haptophore haptophore NNP 50458 269 25 , , , 50458 269 26 " " '' 50458 269 27 is be VBZ 50458 269 28 that that DT 50458 269 29 which which WDT 50458 269 30 enables enable VBZ 50458 269 31 the the DT 50458 269 32 toxin toxin NN 50458 269 33 to to TO 50458 269 34 attach attach VB 50458 269 35 itself -PRON- PRP 50458 269 36 to to IN 50458 269 37 any any DT 50458 269 38 cellular cellular JJ 50458 269 39 element element NN 50458 269 40 whatever whatever WDT 50458 269 41 , , , 50458 269 42 and and CC 50458 269 43 which which WDT 50458 269 44 it -PRON- PRP 50458 269 45 then then RB 50458 269 46 renders render VBZ 50458 269 47 non non JJ 50458 269 48 - - JJ 50458 269 49 toxic toxic JJ 50458 269 50 by by IN 50458 269 51 means mean NNS 50458 269 52 of of IN 50458 269 53 the the DT 50458 269 54 other other JJ 50458 269 55 , , , 50458 269 56 or or CC 50458 269 57 " " `` 50458 269 58 toxophore toxophore NN 50458 269 59 , , , 50458 269 60 " " '' 50458 269 61 group group NN 50458 269 62 . . . 50458 270 1 We -PRON- PRP 50458 270 2 will will MD 50458 270 3 particularize particularize VB 50458 270 4 farther farther RB 50458 270 5 on on IN 50458 270 6 regarding regard VBG 50458 270 7 this this DT 50458 270 8 very very RB 50458 270 9 important important JJ 50458 270 10 conception conception NN 50458 270 11 . . . 50458 271 1 = = NFP 50458 271 2 Origin origin NN 50458 271 3 of of IN 50458 271 4 the the DT 50458 271 5 Toxins.=--These toxins.=--these JJ 50458 271 6 toxic toxic JJ 50458 271 7 bodies body NNS 50458 271 8 result result VBP 50458 271 9 either either CC 50458 271 10 as as IN 50458 271 11 the the DT 50458 271 12 products product NNS 50458 271 13 of of IN 50458 271 14 the the DT 50458 271 15 secretion secretion NN 50458 271 16 of of IN 50458 271 17 microbial microbial JJ 50458 271 18 life life NN 50458 271 19 , , , 50458 271 20 or or CC 50458 271 21 as as IN 50458 271 22 the the DT 50458 271 23 result result NN 50458 271 24 of of IN 50458 271 25 the the DT 50458 271 26 normal normal JJ 50458 271 27 functionation functionation NN 50458 271 28 of of IN 50458 271 29 cellular cellular JJ 50458 271 30 life life NN 50458 271 31 in in IN 50458 271 32 the the DT 50458 271 33 higher high JJR 50458 271 34 vegetable vegetable NN 50458 271 35 or or CC 50458 271 36 animal animal NN 50458 271 37 organisms organism NNS 50458 271 38 . . . 50458 272 1 They -PRON- PRP 50458 272 2 are be VBP 50458 272 3 the the DT 50458 272 4 direct direct JJ 50458 272 5 products product NNS 50458 272 6 of of IN 50458 272 7 life life NN 50458 272 8 , , , 50458 272 9 and and CC 50458 272 10 do do VBP 50458 272 11 not not RB 50458 272 12 result result VB 50458 272 13 , , , 50458 272 14 as as IN 50458 272 15 was be VBD 50458 272 16 formerly formerly RB 50458 272 17 believed believe VBN 50458 272 18 , , , 50458 272 19 from from IN 50458 272 20 a a DT 50458 272 21 more more RBR 50458 272 22 or or CC 50458 272 23 less less RBR 50458 272 24 profound profound JJ 50458 272 25 modification modification NN 50458 272 26 of of IN 50458 272 27 the the DT 50458 272 28 more more RBR 50458 272 29 or or CC 50458 272 30 less less RBR 50458 272 31 complex complex JJ 50458 272 32 albuminoids albuminoid NNS 50458 272 33 that that WDT 50458 272 34 serve serve VBP 50458 272 35 as as IN 50458 272 36 a a DT 50458 272 37 food food NN 50458 272 38 for for IN 50458 272 39 the the DT 50458 272 40 various various JJ 50458 272 41 species specie NNS 50458 272 42 of of IN 50458 272 43 microbes microbe NNS 50458 272 44 , , , 50458 272 45 or or CC 50458 272 46 for for IN 50458 272 47 the the DT 50458 272 48 cellular cellular JJ 50458 272 49 elements element NNS 50458 272 50 . . . 50458 273 1 The the DT 50458 273 2 vegetable vegetable NN 50458 273 3 toxins toxin NNS 50458 273 4 are be VBP 50458 273 5 less less RBR 50458 273 6 numerous numerous JJ 50458 273 7 than than IN 50458 273 8 the the DT 50458 273 9 animal animal NN 50458 273 10 toxins toxin NNS 50458 273 11 . . . 50458 274 1 They -PRON- PRP 50458 274 2 are be VBP 50458 274 3 met meet VBN 50458 274 4 with with IN 50458 274 5 , , , 50458 274 6 nevertheless nevertheless RB 50458 274 7 , , , 50458 274 8 in in IN 50458 274 9 almost almost RB 50458 274 10 all all DT 50458 274 11 mushrooms mushroom NNS 50458 274 12 which which WDT 50458 274 13 are be VBP 50458 274 14 reputed repute VBN 50458 274 15 or or CC 50458 274 16 known know VBN 50458 274 17 to to TO 50458 274 18 be be VB 50458 274 19 toxic toxic JJ 50458 274 20 ; ; : 50458 274 21 the the DT 50458 274 22 seed seed NN 50458 274 23 of of IN 50458 274 24 the the DT 50458 274 25 castor castor NN 50458 274 26 plant plant NN 50458 274 27 contains contain VBZ 50458 274 28 a a DT 50458 274 29 very very RB 50458 274 30 toxic toxic JJ 50458 274 31 vegetable vegetable NN 50458 274 32 albuminoid albuminoid NN 50458 274 33 , , , 50458 274 34 as as IN 50458 274 35 is be VBZ 50458 274 36 likewise likewise RB 50458 274 37 the the DT 50458 274 38 case case NN 50458 274 39 with with IN 50458 274 40 Abrus Abrus NNP 50458 274 41 precatorius precatorius NN 50458 274 42 ( ( -LRB- 50458 274 43 jequirity jequirity NN 50458 274 44 - - HYPH 50458 274 45 bean bean NN 50458 274 46 ) ) -RRB- 50458 274 47 , , , 50458 274 48 and and CC 50458 274 49 certain certain JJ 50458 274 50 others other NNS 50458 274 51 . . . 50458 275 1 The the DT 50458 275 2 true true JJ 50458 275 3 physiological physiological JJ 50458 275 4 toxins toxin NNS 50458 275 5 occupy occupy VBP 50458 275 6 a a DT 50458 275 7 very very RB 50458 275 8 important important JJ 50458 275 9 place place NN 50458 275 10 in in IN 50458 275 11 the the DT 50458 275 12 realization realization NN 50458 275 13 of of IN 50458 275 14 the the DT 50458 275 15 conditions condition NNS 50458 275 16 that that WDT 50458 275 17 govern govern VBP 50458 275 18 health health NN 50458 275 19 , , , 50458 275 20 sickness sickness NN 50458 275 21 , , , 50458 275 22 and and CC 50458 275 23 death death NN 50458 275 24 . . . 50458 276 1 We -PRON- PRP 50458 276 2 will will MD 50458 276 3 see see VB 50458 276 4 later later RB 50458 276 5 on on RB 50458 276 6 that that IN 50458 276 7 they -PRON- PRP 50458 276 8 are be VBP 50458 276 9 met meet VBN 50458 276 10 with with IN 50458 276 11 in in IN 50458 276 12 quite quite RB 50458 276 13 large large JJ 50458 276 14 number number NN 50458 276 15 in in IN 50458 276 16 the the DT 50458 276 17 bladder bladder NN 50458 276 18 , , , 50458 276 19 whence whence NN 50458 276 20 they -PRON- PRP 50458 276 21 are be VBP 50458 276 22 voided void VBN 50458 276 23 in in IN 50458 276 24 the the DT 50458 276 25 urine urine NN 50458 276 26 . . . 50458 277 1 Their -PRON- PRP$ 50458 277 2 number number NN 50458 277 3 varies vary VBZ 50458 277 4 considerably considerably RB 50458 277 5 , , , 50458 277 6 according accord VBG 50458 277 7 to to IN 50458 277 8 diverse diverse JJ 50458 277 9 influences influence NNS 50458 277 10 ( ( -LRB- 50458 277 11 waking waking NN 50458 277 12 , , , 50458 277 13 slumber slumber NNP 50458 277 14 , , , 50458 277 15 eating eat VBG 50458 277 16 , , , 50458 277 17 fasting fasting NN 50458 277 18 , , , 50458 277 19 fatigue fatigue NN 50458 277 20 , , , 50458 277 21 oxygen oxygen NN 50458 277 22 , , , 50458 277 23 brainwork brainwork NN 50458 277 24 , , , 50458 277 25 health health NN 50458 277 26 , , , 50458 277 27 disease disease NN 50458 277 28 , , , 50458 277 29 etc etc FW 50458 277 30 . . . 50458 277 31 ) ) -RRB- 50458 277 32 . . . 50458 278 1 It -PRON- PRP 50458 278 2 is be VBZ 50458 278 3 necessary necessary JJ 50458 278 4 here here RB 50458 278 5 to to TO 50458 278 6 observe observe VB 50458 278 7 that that IN 50458 278 8 the the DT 50458 278 9 renal renal JJ 50458 278 10 system system NN 50458 278 11 serves serve VBZ 50458 278 12 for for IN 50458 278 13 the the DT 50458 278 14 purification purification NN 50458 278 15 of of IN 50458 278 16 the the DT 50458 278 17 entire entire JJ 50458 278 18 organism organism NN 50458 278 19 , , , 50458 278 20 and and CC 50458 278 21 that that IN 50458 278 22 in in IN 50458 278 23 the the DT 50458 278 24 case case NN 50458 278 25 of of IN 50458 278 26 normal normal JJ 50458 278 27 life life NN 50458 278 28 we -PRON- PRP 50458 278 29 will will MD 50458 278 30 find find VB 50458 278 31 in in IN 50458 278 32 the the DT 50458 278 33 renal renal JJ 50458 278 34 system system NN 50458 278 35 a a DT 50458 278 36 large large JJ 50458 278 37 portion portion NN 50458 278 38 of of IN 50458 278 39 the the DT 50458 278 40 products product NNS 50458 278 41 of of IN 50458 278 42 the the DT 50458 278 43 cellular cellular JJ 50458 278 44 secretion secretion NN 50458 278 45 of of IN 50458 278 46 the the DT 50458 278 47 organism organism NN 50458 278 48 , , , 50458 278 49 and and CC 50458 278 50 among among IN 50458 278 51 the the DT 50458 278 52 number number NN 50458 278 53 there there EX 50458 278 54 are be VBP 50458 278 55 found find VBN 50458 278 56 , , , 50458 278 57 as as IN 50458 278 58 we -PRON- PRP 50458 278 59 know know VBP 50458 278 60 , , , 50458 278 61 a a DT 50458 278 62 certain certain JJ 50458 278 63 number number NN 50458 278 64 of of IN 50458 278 65 alkaloidal alkaloidal NN 50458 278 66 bases basis NNS 50458 278 67 . . . 50458 279 1 We -PRON- PRP 50458 279 2 will will MD 50458 279 3 take take VB 50458 279 4 up up RP 50458 279 5 later later RB 50458 279 6 the the DT 50458 279 7 subject subject NN 50458 279 8 of of IN 50458 279 9 urinary urinary JJ 50458 279 10 toxicity toxicity NN 50458 279 11 . . . 50458 280 1 = = NFP 50458 280 2 Autointoxications.=--The autointoxications.=--the DT 50458 280 3 toxins toxin NNS 50458 280 4 are be VBP 50458 280 5 also also RB 50458 280 6 encountered encounter VBN 50458 280 7 , , , 50458 280 8 and and CC 50458 280 9 often often RB 50458 280 10 in in IN 50458 280 11 some some DT 50458 280 12 number number NN 50458 280 13 , , , 50458 280 14 in in IN 50458 280 15 the the DT 50458 280 16 muscular muscular JJ 50458 280 17 tissues tissue NNS 50458 280 18 and and CC 50458 280 19 in in IN 50458 280 20 the the DT 50458 280 21 blood blood NN 50458 280 22 , , , 50458 280 23 particularly particularly RB 50458 280 24 in in IN 50458 280 25 those those DT 50458 280 26 of of IN 50458 280 27 batrachians batrachian NNS 50458 280 28 , , , 50458 280 29 mureids mureid NNS 50458 280 30 , , , 50458 280 31 and and CC 50458 280 32 saurians saurians NNPS 50458 280 33 . . . 50458 281 1 In in IN 50458 281 2 the the DT 50458 281 3 organism organism NN 50458 281 4 these these DT 50458 281 5 toxins toxin NNS 50458 281 6 , , , 50458 281 7 developed develop VBN 50458 281 8 by by IN 50458 281 9 the the DT 50458 281 10 activity activity NN 50458 281 11 of of IN 50458 281 12 the the DT 50458 281 13 various various JJ 50458 281 14 cells cell NNS 50458 281 15 , , , 50458 281 16 may may MD 50458 281 17 cause cause VB 50458 281 18 autointoxication autointoxication NN 50458 281 19 whenever whenever WRB 50458 281 20 , , , 50458 281 21 for for IN 50458 281 22 one one CD 50458 281 23 cause cause NN 50458 281 24 or or CC 50458 281 25 another another DT 50458 281 26 , , , 50458 281 27 their -PRON- PRP$ 50458 281 28 normal normal JJ 50458 281 29 elimination elimination NN 50458 281 30 ceases cease NNS 50458 281 31 . . . 50458 282 1 " " `` 50458 282 2 Although although IN 50458 282 3 there there EX 50458 282 4 are be VBP 50458 282 5 an an DT 50458 282 6 infinity infinity NN 50458 282 7 of of IN 50458 282 8 diseases disease NNS 50458 282 9 , , , 50458 282 10 " " '' 50458 282 11 remarked remark VBD 50458 282 12 Prof. Prof. NNP 50458 282 13 Bouchard Bouchard NNP 50458 282 14 , , , 50458 282 15 " " `` 50458 282 16 there there EX 50458 282 17 are be VBP 50458 282 18 but but IN 50458 282 19 a a DT 50458 282 20 few few JJ 50458 282 21 ways way NNS 50458 282 22 of of IN 50458 282 23 becoming become VBG 50458 282 24 ill ill JJ 50458 282 25 . . . 50458 282 26 " " '' 50458 282 27 Of of IN 50458 282 28 these these DT 50458 282 29 ways way NNS 50458 282 30 that that DT 50458 282 31 of of IN 50458 282 32 autointoxication autointoxication NN 50458 282 33 is be VBZ 50458 282 34 the the DT 50458 282 35 most most RBS 50458 282 36 frequent frequent JJ 50458 282 37 . . . 50458 283 1 " " `` 50458 283 2 What what WP 50458 283 3 else else RB 50458 283 4 is be VBZ 50458 283 5 it -PRON- PRP 50458 283 6 , , , 50458 283 7 then then RB 50458 283 8 , , , 50458 283 9 " " '' 50458 283 10 says say VBZ 50458 283 11 Prof. Prof. NNP 50458 283 12 Charrin Charrin NNP 50458 283 13 , , , 50458 283 14 " " `` 50458 283 15 in in IN 50458 283 16 the the DT 50458 283 17 last last JJ 50458 283 18 analysis analysis NN 50458 283 19 , , , 50458 283 20 but but CC 50458 283 21 to to TO 50458 283 22 die die VB 50458 283 23 from from IN 50458 283 24 affections affection NNS 50458 283 25 of of IN 50458 283 26 the the DT 50458 283 27 kidney kidney NN 50458 283 28 , , , 50458 283 29 the the DT 50458 283 30 liver liver NN 50458 283 31 , , , 50458 283 32 the the DT 50458 283 33 heart heart NN 50458 283 34 , , , 50458 283 35 the the DT 50458 283 36 lung lung NN 50458 283 37 , , , 50458 283 38 etc etc FW 50458 283 39 . . FW 50458 283 40 , , , 50458 283 41 if if IN 50458 283 42 it -PRON- PRP 50458 283 43 be be VBP 50458 283 44 not not RB 50458 283 45 to to TO 50458 283 46 succumb succumb VB 50458 283 47 because because IN 50458 283 48 of of IN 50458 283 49 the the DT 50458 283 50 lack lack NN 50458 283 51 of of IN 50458 283 52 oxygen oxygen NN 50458 283 53 , , , 50458 283 54 the the DT 50458 283 55 accumulation accumulation NN 50458 283 56 of of IN 50458 283 57 carbonic carbonic JJ 50458 283 58 acid acid NN 50458 283 59 , , , 50458 283 60 the the DT 50458 283 61 influence influence NN 50458 283 62 of of IN 50458 283 63 the the DT 50458 283 64 numerous numerous JJ 50458 283 65 urinary urinary JJ 50458 283 66 poisons poison NNS 50458 283 67 , , , 50458 283 68 the the DT 50458 283 69 action action NN 50458 283 70 of of IN 50458 283 71 acids acid NNS 50458 283 72 , , , 50458 283 73 of of IN 50458 283 74 salts salt NNS 50458 283 75 , , , 50458 283 76 of of IN 50458 283 77 biliary biliary JJ 50458 283 78 pigments pigment NNS 50458 283 79 , , , 50458 283 80 or or CC 50458 283 81 the the DT 50458 283 82 effect effect NN 50458 283 83 of of IN 50458 283 84 noxious noxious JJ 50458 283 85 principles principle NNS 50458 283 86 , , , 50458 283 87 which which WDT 50458 283 88 the the DT 50458 283 89 hepatic hepatic JJ 50458 283 90 cell cell NN 50458 283 91 must must MD 50458 283 92 normally normally RB 50458 283 93 destroy destroy VB 50458 283 94 or or CC 50458 283 95 at at IN 50458 283 96 least least JJS 50458 283 97 attenuate attenuate NN 50458 283 98 . . . 50458 283 99 " " '' 50458 284 1 These these DT 50458 284 2 autointoxications autointoxication NNS 50458 284 3 , , , 50458 284 4 always always RB 50458 284 5 due due JJ 50458 284 6 to to IN 50458 284 7 poor poor JJ 50458 284 8 elimination elimination NN 50458 284 9 of of IN 50458 284 10 toxic toxic JJ 50458 284 11 principles principle NNS 50458 284 12 , , , 50458 284 13 toxins toxin NNS 50458 284 14 formed form VBN 50458 284 15 in in IN 50458 284 16 very very RB 50458 284 17 great great JJ 50458 284 18 number number NN 50458 284 19 in in IN 50458 284 20 the the DT 50458 284 21 organism organism NN 50458 284 22 , , , 50458 284 23 and and CC 50458 284 24 which which WDT 50458 284 25 the the DT 50458 284 26 normal normal JJ 50458 284 27 modes mode NNS 50458 284 28 of of IN 50458 284 29 evacuation evacuation NN 50458 284 30 or or CC 50458 284 31 destruction destruction NN 50458 284 32 do do VBP 50458 284 33 not not RB 50458 284 34 eliminate eliminate VB 50458 284 35 , , , 50458 284 36 are be VBP 50458 284 37 always always RB 50458 284 38 found find VBN 50458 284 39 to to TO 50458 284 40 be be VB 50458 284 41 the the DT 50458 284 42 cause cause NN 50458 284 43 of of IN 50458 284 44 all all DT 50458 284 45 diseases disease NNS 50458 284 46 , , , 50458 284 47 even even RB 50458 284 48 those those DT 50458 284 49 that that WDT 50458 284 50 are be VBP 50458 284 51 manifested manifest VBN 50458 284 52 by by IN 50458 284 53 attacks attack NNS 50458 284 54 of of IN 50458 284 55 the the DT 50458 284 56 cerebro cerebro JJ 50458 284 57 - - HYPH 50458 284 58 spinal spinal JJ 50458 284 59 axis axis NN 50458 284 60 , , , 50458 284 61 and and CC 50458 284 62 that that DT 50458 284 63 exhibit exhibit NN 50458 284 64 variously variously RB 50458 284 65 mania mania NN 50458 284 66 , , , 50458 284 67 insanity insanity NN 50458 284 68 , , , 50458 284 69 symptoms symptom NNS 50458 284 70 of of IN 50458 284 71 hyperexcitability hyperexcitability NN 50458 284 72 , , , 50458 284 73 etc etc FW 50458 284 74 . . . 50458 285 1 These these DT 50458 285 2 autointoxications autointoxication NNS 50458 285 3 are be VBP 50458 285 4 controlled control VBN 50458 285 5 by by IN 50458 285 6 the the DT 50458 285 7 nervous nervous JJ 50458 285 8 system system NN 50458 285 9 , , , 50458 285 10 and and CC 50458 285 11 the the DT 50458 285 12 latter latter JJ 50458 285 13 alone alone RB 50458 285 14 is be VBZ 50458 285 15 the the DT 50458 285 16 cause cause NN 50458 285 17 of of IN 50458 285 18 a a DT 50458 285 19 larger large JJR 50458 285 20 number number NN 50458 285 21 of of IN 50458 285 22 maladies malady NNS 50458 285 23 than than IN 50458 285 24 is be VBZ 50458 285 25 generally generally RB 50458 285 26 believed believe VBN 50458 285 27 ; ; : 50458 285 28 in in IN 50458 285 29 fact fact NN 50458 285 30 , , , 50458 285 31 if if IN 50458 285 32 the the DT 50458 285 33 mechanism mechanism NN 50458 285 34 of of IN 50458 285 35 nutrition nutrition NN 50458 285 36 be be VB 50458 285 37 reduced reduce VBN 50458 285 38 to to IN 50458 285 39 its -PRON- PRP$ 50458 285 40 most most RBS 50458 285 41 simple simple JJ 50458 285 42 elements element NNS 50458 285 43 , , , 50458 285 44 it -PRON- PRP 50458 285 45 will will MD 50458 285 46 be be VB 50458 285 47 seen see VBN 50458 285 48 to to TO 50458 285 49 consist consist VB 50458 285 50 of of IN 50458 285 51 the the DT 50458 285 52 penetration penetration NN 50458 285 53 of of IN 50458 285 54 the the DT 50458 285 55 foods food NNS 50458 285 56 , , , 50458 285 57 of of IN 50458 285 58 the the DT 50458 285 59 plasmatic plasmatic JJ 50458 285 60 principles principle NNS 50458 285 61 , , , 50458 285 62 to to IN 50458 285 63 the the DT 50458 285 64 cells cell NNS 50458 285 65 ; ; : 50458 285 66 of of IN 50458 285 67 their -PRON- PRP$ 50458 285 68 transformation transformation NN 50458 285 69 within within IN 50458 285 70 the the DT 50458 285 71 interior interior NN 50458 285 72 of of IN 50458 285 73 the the DT 50458 285 74 cells cell NNS 50458 285 75 , , , 50458 285 76 and and CC 50458 285 77 finally finally RB 50458 285 78 the the DT 50458 285 79 rejection rejection NN 50458 285 80 of of IN 50458 285 81 all all PDT 50458 285 82 the the DT 50458 285 83 matter matter NN 50458 285 84 that that WDT 50458 285 85 could could MD 50458 285 86 not not RB 50458 285 87 be be VB 50458 285 88 utilized utilize VBN 50458 285 89 . . . 50458 286 1 It -PRON- PRP 50458 286 2 is be VBZ 50458 286 3 the the DT 50458 286 4 nervous nervous JJ 50458 286 5 system system NN 50458 286 6 that that WDT 50458 286 7 commands command VBZ 50458 286 8 or or CC 50458 286 9 dominates dominate VBZ 50458 286 10 this this DT 50458 286 11 mechanism mechanism NN 50458 286 12 , , , 50458 286 13 that that WDT 50458 286 14 controls control VBZ 50458 286 15 the the DT 50458 286 16 taking taking NN 50458 286 17 - - HYPH 50458 286 18 up up NN 50458 286 19 of of IN 50458 286 20 assimilable assimilable JJ 50458 286 21 elements element NNS 50458 286 22 and and CC 50458 286 23 the the DT 50458 286 24 elimination elimination NN 50458 286 25 of of IN 50458 286 26 toxic toxic JJ 50458 286 27 principles principle NNS 50458 286 28 , , , 50458 286 29 the the DT 50458 286 30 fruit fruit NN 50458 286 31 of of IN 50458 286 32 assimilation assimilation NN 50458 286 33 or or CC 50458 286 34 disassimilation disassimilation NN 50458 286 35 , , , 50458 286 36 and and CC 50458 286 37 in in IN 50458 286 38 such such PDT 50458 286 39 a a DT 50458 286 40 manner manner NN 50458 286 41 , , , 50458 286 42 in in IN 50458 286 43 fact fact NN 50458 286 44 , , , 50458 286 45 that that IN 50458 286 46 this this DT 50458 286 47 same same JJ 50458 286 48 nervous nervous JJ 50458 286 49 system system NN 50458 286 50 can can MD 50458 286 51 , , , 50458 286 52 at at IN 50458 286 53 its -PRON- PRP$ 50458 286 54 will will NN 50458 286 55 , , , 50458 286 56 cause cause VB 50458 286 57 starvation starvation NN 50458 286 58 , , , 50458 286 59 or or CC 50458 286 60 intoxicate intoxicate VBP 50458 286 61 . . . 50458 287 1 The the DT 50458 287 2 marvelous marvelous JJ 50458 287 3 cures cure NNS 50458 287 4 obtained obtain VBN 50458 287 5 by by IN 50458 287 6 magnetic magnetic JJ 50458 287 7 methods method NNS 50458 287 8 are be VBP 50458 287 9 due due JJ 50458 287 10 to to IN 50458 287 11 no no DT 50458 287 12 other other JJ 50458 287 13 causes cause NNS 50458 287 14 than than IN 50458 287 15 favorable favorable JJ 50458 287 16 changes change NNS 50458 287 17 in in IN 50458 287 18 the the DT 50458 287 19 nervous nervous JJ 50458 287 20 system system NN 50458 287 21 . . . 50458 288 1 = = NFP 50458 288 2 General General NNP 50458 288 3 Mode Mode NNP 50458 288 4 of of IN 50458 288 5 Action.=--The Action.=--The NNP 50458 288 6 toxins toxin NNS 50458 288 7 , , , 50458 288 8 of of IN 50458 288 9 whatever whatever WDT 50458 288 10 kind kind NN 50458 288 11 , , , 50458 288 12 always always RB 50458 288 13 behave behave VB 50458 288 14 like like IN 50458 288 15 diastases diastasis NNS 50458 288 16 , , , 50458 288 17 in in IN 50458 288 18 the the DT 50458 288 19 sense sense NN 50458 288 20 that that IN 50458 288 21 their -PRON- PRP$ 50458 288 22 definite definite JJ 50458 288 23 action action NN 50458 288 24 appears appear VBZ 50458 288 25 to to TO 50458 288 26 be be VB 50458 288 27 absolutely absolutely RB 50458 288 28 independent independent JJ 50458 288 29 of of IN 50458 288 30 their -PRON- PRP$ 50458 288 31 mass mass NN 50458 288 32 , , , 50458 288 33 and and CC 50458 288 34 that that IN 50458 288 35 imponderable imponderable JJ 50458 288 36 quantities quantity NNS 50458 288 37 suffice suffice VBP 50458 288 38 to to TO 50458 288 39 cause cause VB 50458 288 40 serious serious JJ 50458 288 41 morbid morbid NN 50458 288 42 affections affection NNS 50458 288 43 and and CC 50458 288 44 profound profound JJ 50458 288 45 modifications modification NNS 50458 288 46 in in IN 50458 288 47 nutrition nutrition NN 50458 288 48 . . . 50458 289 1 Koch Koch NNP 50458 289 2 has have VBZ 50458 289 3 shown show VBN 50458 289 4 that that IN 50458 289 5 tuberculin tuberculin NN 50458 289 6 is be VBZ 50458 289 7 capable capable JJ 50458 289 8 of of IN 50458 289 9 affecting affect VBG 50458 289 10 60 60 CD 50458 289 11 trillion trillion CD 50458 289 12 times time NNS 50458 289 13 its -PRON- PRP$ 50458 289 14 weight weight NN 50458 289 15 of of IN 50458 289 16 the the DT 50458 289 17 living live VBG 50458 289 18 human human JJ 50458 289 19 being being NN 50458 289 20 . . . 50458 290 1 According accord VBG 50458 290 2 to to IN 50458 290 3 Vaillard Vaillard NNP 50458 290 4 one one CD 50458 290 5 milligramme milligramme NN 50458 290 6 of of IN 50458 290 7 tetanus tetanus NN 50458 290 8 toxin toxin NN 50458 290 9 will will MD 50458 290 10 kill kill VB 50458 290 11 a a DT 50458 290 12 horse horse NN 50458 290 13 weighing weigh VBG 50458 290 14 600 600 CD 50458 290 15 kilos kilo NNS 50458 290 16 . . . 50458 291 1 These these DT 50458 291 2 two two CD 50458 291 3 examples example NNS 50458 291 4 show show VBP 50458 291 5 what what WP 50458 291 6 an an DT 50458 291 7 enormous enormous JJ 50458 291 8 power power NN 50458 291 9 the the DT 50458 291 10 toxins toxin NNS 50458 291 11 possess possess VBP 50458 291 12 . . . 50458 292 1 My -PRON- PRP$ 50458 292 2 views view NNS 50458 292 3 regarding regard VBG 50458 292 4 the the DT 50458 292 5 manner manner NN 50458 292 6 in in IN 50458 292 7 which which WDT 50458 292 8 diastases diastasis NNS 50458 292 9 act act VBP 50458 292 10 I -PRON- PRP 50458 292 11 have have VBP 50458 292 12 developed develop VBN 50458 292 13 at at IN 50458 292 14 length length NN 50458 292 15 in in IN 50458 292 16 my -PRON- PRP$ 50458 292 17 work work NN 50458 292 18 _ _ NNP 50458 292 19 Nature Nature NNP 50458 292 20 des des NNP 50458 292 21 Diastases Diastases NNP 50458 292 22 _ _ NNP 50458 292 23 . . . 50458 293 1 The the DT 50458 293 2 close close JJ 50458 293 3 analogy analogy NN 50458 293 4 between between IN 50458 293 5 these these DT 50458 293 6 substances substance NNS 50458 293 7 and and CC 50458 293 8 the the DT 50458 293 9 toxins toxin NNS 50458 293 10 , , , 50458 293 11 an an DT 50458 293 12 analogy analogy NN 50458 293 13 upon upon IN 50458 293 14 which which WDT 50458 293 15 , , , 50458 293 16 moreover moreover RB 50458 293 17 , , , 50458 293 18 I -PRON- PRP 50458 293 19 have have VBP 50458 293 20 dwelt dwell VBN 50458 293 21 at at IN 50458 293 22 some some DT 50458 293 23 length length NN 50458 293 24 , , , 50458 293 25 permits permit VBZ 50458 293 26 me -PRON- PRP 50458 293 27 to to TO 50458 293 28 refer refer VB 50458 293 29 the the DT 50458 293 30 reader reader NN 50458 293 31 who who WP 50458 293 32 is be VBZ 50458 293 33 desirous desirous JJ 50458 293 34 of of IN 50458 293 35 fuller full JJR 50458 293 36 details detail NNS 50458 293 37 to to IN 50458 293 38 the the DT 50458 293 39 small small JJ 50458 293 40 work work NN 50458 293 41 just just RB 50458 293 42 mentioned mention VBD 50458 293 43 . . . 50458 294 1 The the DT 50458 294 2 mode mode NN 50458 294 3 of of IN 50458 294 4 action action NN 50458 294 5 of of IN 50458 294 6 diastases diastasis NNS 50458 294 7 resembles resemble VBZ 50458 294 8 singularly singularly RB 50458 294 9 closely closely RB 50458 294 10 that that DT 50458 294 11 of of IN 50458 294 12 the the DT 50458 294 13 catalytic catalytic JJ 50458 294 14 substances substance NNS 50458 294 15 , , , 50458 294 16 and and CC 50458 294 17 we -PRON- PRP 50458 294 18 will will MD 50458 294 19 admit admit VB 50458 294 20 , , , 50458 294 21 for for IN 50458 294 22 the the DT 50458 294 23 moment moment NN 50458 294 24 , , , 50458 294 25 that that IN 50458 294 26 they -PRON- PRP 50458 294 27 act act VBP 50458 294 28 by by IN 50458 294 29 intermediary intermediary JJ 50458 294 30 combination combination NN 50458 294 31 , , , 50458 294 32 resulting result VBG 50458 294 33 in in IN 50458 294 34 their -PRON- PRP$ 50458 294 35 rapid rapid JJ 50458 294 36 decomposition decomposition NN 50458 294 37 . . . 50458 295 1 We -PRON- PRP 50458 295 2 owe owe VBP 50458 295 3 to to IN 50458 295 4 Ehrlich[31 ehrlich[31 ADD 50458 295 5 ] ] -RRB- 50458 295 6 a a DT 50458 295 7 new new JJ 50458 295 8 conception conception NN 50458 295 9 relative relative JJ 50458 295 10 to to IN 50458 295 11 the the DT 50458 295 12 nature nature NN 50458 295 13 and and CC 50458 295 14 mode mode NN 50458 295 15 of of IN 50458 295 16 action action NN 50458 295 17 of of IN 50458 295 18 the the DT 50458 295 19 diastases diastasis NNS 50458 295 20 , , , 50458 295 21 and and CC 50458 295 22 which which WDT 50458 295 23 to to IN 50458 295 24 - - HYPH 50458 295 25 day day NN 50458 295 26 plays play VBZ 50458 295 27 an an DT 50458 295 28 important important JJ 50458 295 29 rôle rôle NN 50458 295 30 in in IN 50458 295 31 all all DT 50458 295 32 our -PRON- PRP$ 50458 295 33 conceptions conception NNS 50458 295 34 regarding regard VBG 50458 295 35 immunity immunity NN 50458 295 36 . . . 50458 296 1 [ [ -LRB- 50458 296 2 32 32 CD 50458 296 3 ] ] -RRB- 50458 296 4 [ [ -LRB- 50458 296 5 31 31 CD 50458 296 6 ] ] -RRB- 50458 296 7 EHRLICH ehrlich NN 50458 296 8 : : : 50458 296 9 _ _ NNP 50458 296 10 Klinisches Klinisches NNPS 50458 296 11 Jahrbuch Jahrbuch NNP 50458 296 12 _ _ NNP 50458 296 13 , , , 50458 296 14 1897 1897 CD 50458 296 15 , , , 50458 296 16 VI VI NNP 50458 296 17 . . . 50458 297 1 _ _ NNP 50458 297 2 Proceedings Proceedings NNP 50458 297 3 of of IN 50458 297 4 the the DT 50458 297 5 Royal Royal NNP 50458 297 6 Society Society NNP 50458 297 7 _ _ NNP 50458 297 8 , , , 50458 297 9 1900 1900 CD 50458 297 10 , , , 50458 297 11 No no UH 50458 297 12 . . . 50458 298 1 482 482 CD 50458 298 2 , , , 50458 298 3 p. p. NN 50458 298 4 424 424 CD 50458 298 5 . . . 50458 299 1 _ _ NNP 50458 299 2 Nothnagles Nothnagles NNP 50458 299 3 ' ' POS 50458 299 4 specielle specielle NN 50458 299 5 Pathologie Pathologie NNP 50458 299 6 und und JJ 50458 299 7 Therapie Therapie NNP 50458 299 8 _ _ NNP 50458 299 9 , , , 50458 299 10 1901 1901 CD 50458 299 11 , , , 50458 299 12 VIII VIII NNP 50458 299 13 , , , 50458 299 14 Schlussbetrachtungen Schlussbetrachtungen NNP 50458 299 15 , , , 50458 299 16 p. p. NN 50458 299 17 163 163 CD 50458 299 18 . . . 50458 300 1 [ [ -LRB- 50458 300 2 32 32 CD 50458 300 3 ] ] -RRB- 50458 300 4 To to TO 50458 300 5 have have VB 50458 300 6 a a DT 50458 300 7 complete complete JJ 50458 300 8 exposé exposé NN 50458 300 9 regarding regard VBG 50458 300 10 this this DT 50458 300 11 question question NN 50458 300 12 , , , 50458 300 13 it -PRON- PRP 50458 300 14 will will MD 50458 300 15 be be VB 50458 300 16 profitable profitable JJ 50458 300 17 to to TO 50458 300 18 consult consult VB 50458 300 19 No no UH 50458 300 20 . . . 50458 301 1 4 4 CD 50458 301 2 of of IN 50458 301 3 this this DT 50458 301 4 collection collection NN 50458 301 5 on on IN 50458 301 6 _ _ NNP 50458 301 7 Sérums Sérums NNP 50458 301 8 Immunisants Immunisants NNP 50458 301 9 _ _ NNP 50458 301 10 . . . 50458 302 1 According accord VBG 50458 302 2 to to IN 50458 302 3 this this DT 50458 302 4 scientist scientist NN 50458 302 5 , , , 50458 302 6 the the DT 50458 302 7 complex complex JJ 50458 302 8 molecule molecule NN 50458 302 9 of of IN 50458 302 10 albuminoid albuminoid NN 50458 302 11 substances substance NNS 50458 302 12 is be VBZ 50458 302 13 constituted constitute VBN 50458 302 14 by by IN 50458 302 15 a a DT 50458 302 16 fixed fix VBN 50458 302 17 central central JJ 50458 302 18 nucleus nucleus NN 50458 302 19 , , , 50458 302 20 and and CC 50458 302 21 by by IN 50458 302 22 a a DT 50458 302 23 number number NN 50458 302 24 of of IN 50458 302 25 lateral lateral JJ 50458 302 26 chains chain NNS 50458 302 27 or or CC 50458 302 28 receptors receptor NNS 50458 302 29 , , , 50458 302 30 fixed fix VBN 50458 302 31 to to IN 50458 302 32 this this DT 50458 302 33 nucleus nucleus NN 50458 302 34 , , , 50458 302 35 which which WDT 50458 302 36 possess possess VBP 50458 302 37 diverse diverse JJ 50458 302 38 accessory accessory JJ 50458 302 39 functions function NNS 50458 302 40 , , , 50458 302 41 and and CC 50458 302 42 which which WDT 50458 302 43 serve serve VBP 50458 302 44 , , , 50458 302 45 particularly particularly RB 50458 302 46 , , , 50458 302 47 for for IN 50458 302 48 the the DT 50458 302 49 nutrition nutrition NN 50458 302 50 of of IN 50458 302 51 the the DT 50458 302 52 cells cell NNS 50458 302 53 . . . 50458 303 1 These these DT 50458 303 2 receptors receptor NNS 50458 303 3 have have VBP 50458 303 4 a a DT 50458 303 5 great great JJ 50458 303 6 affinity affinity NN 50458 303 7 for for IN 50458 303 8 the the DT 50458 303 9 various various JJ 50458 303 10 substances substance NNS 50458 303 11 necessary necessary JJ 50458 303 12 for for IN 50458 303 13 the the DT 50458 303 14 support support NN 50458 303 15 of of IN 50458 303 16 the the DT 50458 303 17 living live VBG 50458 303 18 elements element NNS 50458 303 19 , , , 50458 303 20 and and CC 50458 303 21 they -PRON- PRP 50458 303 22 seize seize VBP 50458 303 23 upon upon IN 50458 303 24 the the DT 50458 303 25 alimentary alimentary JJ 50458 303 26 substances substance NNS 50458 303 27 , , , 50458 303 28 in in IN 50458 303 29 normal normal JJ 50458 303 30 life life NN 50458 303 31 , , , 50458 303 32 just just RB 50458 303 33 as as IN 50458 303 34 a a DT 50458 303 35 leaf leaf NN 50458 303 36 of of IN 50458 303 37 the the DT 50458 303 38 _ _ NNP 50458 303 39 Dionæa Dionæa NNP 50458 303 40 _ _ NNP 50458 303 41 seizes seize VBZ 50458 303 42 a a DT 50458 303 43 fly fly NN 50458 303 44 which which WDT 50458 303 45 serves serve VBZ 50458 303 46 as as IN 50458 303 47 its -PRON- PRP$ 50458 303 48 food food NN 50458 303 49 . . . 50458 304 1 In in IN 50458 304 2 these these DT 50458 304 3 special special JJ 50458 304 4 conditions condition NNS 50458 304 5 the the DT 50458 304 6 receptors receptor NNS 50458 304 7 may may MD 50458 304 8 attach attach VB 50458 304 9 themselves -PRON- PRP 50458 304 10 to to IN 50458 304 11 the the DT 50458 304 12 complex complex JJ 50458 304 13 molecules molecule NNS 50458 304 14 of of IN 50458 304 15 albuminoid albuminoid NN 50458 304 16 substances substance NNS 50458 304 17 , , , 50458 304 18 such such JJ 50458 304 19 as as IN 50458 304 20 the the DT 50458 304 21 different different JJ 50458 304 22 toxins toxin NNS 50458 304 23 . . . 50458 305 1 Ehrlich ehrlich NN 50458 305 2 supposes suppose NNS 50458 305 3 , , , 50458 305 4 as as IN 50458 305 5 we -PRON- PRP 50458 305 6 have have VBP 50458 305 7 already already RB 50458 305 8 seen see VBN 50458 305 9 , , , 50458 305 10 that that IN 50458 305 11 a a DT 50458 305 12 toxin toxin NN 50458 305 13 contains contain VBZ 50458 305 14 two two CD 50458 305 15 special special JJ 50458 305 16 groups group NNS 50458 305 17 -- -- : 50458 305 18 a a DT 50458 305 19 _ _ NNP 50458 305 20 toxophore toxophore NN 50458 305 21 _ _ NNP 50458 305 22 group group NN 50458 305 23 , , , 50458 305 24 which which WDT 50458 305 25 poisons poison NNS 50458 305 26 , , , 50458 305 27 and and CC 50458 305 28 a a DT 50458 305 29 _ _ NNP 50458 305 30 haptophore haptophore NN 50458 305 31 _ _ NNP 50458 305 32 group group NN 50458 305 33 , , , 50458 305 34 which which WDT 50458 305 35 combines combine VBZ 50458 305 36 with with IN 50458 305 37 the the DT 50458 305 38 receptor receptor NN 50458 305 39 . . . 50458 306 1 According accord VBG 50458 306 2 to to IN 50458 306 3 this this DT 50458 306 4 theory theory NN 50458 306 5 , , , 50458 306 6 the the DT 50458 306 7 toxophore toxophore NN 50458 306 8 group group NN 50458 306 9 of of IN 50458 306 10 a a DT 50458 306 11 toxin toxin NN 50458 306 12 can can MD 50458 306 13 act act VB 50458 306 14 on on IN 50458 306 15 an an DT 50458 306 16 organism organism NN 50458 306 17 _ _ NNP 50458 306 18 only only RB 50458 306 19 _ _ NNP 50458 306 20 when when WRB 50458 306 21 the the DT 50458 306 22 haptophore haptophore NN 50458 306 23 group group NN 50458 306 24 of of IN 50458 306 25 the the DT 50458 306 26 toxin toxin NN 50458 306 27 encounters encounter VBZ 50458 306 28 a a DT 50458 306 29 suitable suitable JJ 50458 306 30 attachment attachment NN 50458 306 31 or or CC 50458 306 32 receptor receptor NN 50458 306 33 . . . 50458 307 1 The the DT 50458 307 2 receptors receptor NNS 50458 307 3 attached attach VBD 50458 307 4 to to IN 50458 307 5 the the DT 50458 307 6 living live VBG 50458 307 7 protoplasmic protoplasmic NN 50458 307 8 molecule molecule NN 50458 307 9 attract attract VBP 50458 307 10 the the DT 50458 307 11 toxin toxin NN 50458 307 12 , , , 50458 307 13 just just RB 50458 307 14 as as IN 50458 307 15 a a DT 50458 307 16 lightning lightning NN 50458 307 17 - - HYPH 50458 307 18 rod rod NN 50458 307 19 attracts attract VBZ 50458 307 20 the the DT 50458 307 21 lightning lightning NN 50458 307 22 . . . 50458 308 1 It -PRON- PRP 50458 308 2 is be VBZ 50458 308 3 hence hence RB 50458 308 4 clearly clearly RB 50458 308 5 proved prove VBN 50458 308 6 that that IN 50458 308 7 the the DT 50458 308 8 toxigenic toxigenic JJ 50458 308 9 poisons poison NNS 50458 308 10 exert exert VBP 50458 308 11 their -PRON- PRP$ 50458 308 12 noxious noxious JJ 50458 308 13 action action NN 50458 308 14 on on IN 50458 308 15 the the DT 50458 308 16 cellular cellular JJ 50458 308 17 elements element NNS 50458 308 18 of of IN 50458 308 19 sensitive sensitive JJ 50458 308 20 organisms organism NNS 50458 308 21 , , , 50458 308 22 by by IN 50458 308 23 entering enter VBG 50458 308 24 into into IN 50458 308 25 combination combination NN 50458 308 26 with with IN 50458 308 27 these these DT 50458 308 28 . . . 50458 309 1 Experience experience NN 50458 309 2 has have VBZ 50458 309 3 shown show VBN 50458 309 4 that that IN 50458 309 5 they -PRON- PRP 50458 309 6 attach attach VBP 50458 309 7 themselves -PRON- PRP 50458 309 8 , , , 50458 309 9 in in IN 50458 309 10 a a DT 50458 309 11 most most RBS 50458 309 12 rigorously rigorously RB 50458 309 13 elective elective JJ 50458 309 14 manner manner NN 50458 309 15 , , , 50458 309 16 to to IN 50458 309 17 the the DT 50458 309 18 tissues tissue NNS 50458 309 19 , , , 50458 309 20 and and CC 50458 309 21 rapidly rapidly RB 50458 309 22 disappear disappear VBP 50458 309 23 from from IN 50458 309 24 the the DT 50458 309 25 general general JJ 50458 309 26 circulation circulation NN 50458 309 27 . . . 50458 310 1 Numerous numerous JJ 50458 310 2 facts fact NNS 50458 310 3 , , , 50458 310 4 clearly clearly RB 50458 310 5 established establish VBN 50458 310 6 , , , 50458 310 7 attest attest VB 50458 310 8 the the DT 50458 310 9 reality reality NN 50458 310 10 of of IN 50458 310 11 this this DT 50458 310 12 fixation fixation NN 50458 310 13 or or CC 50458 310 14 attachment attachment NN 50458 310 15 . . . 50458 311 1 It -PRON- PRP 50458 311 2 is be VBZ 50458 311 3 thus thus RB 50458 311 4 that that IN 50458 311 5 von von NNP 50458 311 6 Behring Behring NNP 50458 311 7 and and CC 50458 311 8 Wernicke[33 wernicke[33 CD 50458 311 9 ] ] -RRB- 50458 311 10 sought seek VBD 50458 311 11 to to TO 50458 311 12 ascertain ascertain VB 50458 311 13 the the DT 50458 311 14 quantity quantity NN 50458 311 15 of of IN 50458 311 16 antitoxin antitoxin NN 50458 311 17 ( ( -LRB- 50458 311 18 we -PRON- PRP 50458 311 19 will will MD 50458 311 20 see see VB 50458 311 21 farther farther RB 50458 311 22 on on IN 50458 311 23 that that IN 50458 311 24 this this DT 50458 311 25 name name NN 50458 311 26 is be VBZ 50458 311 27 given give VBN 50458 311 28 to to IN 50458 311 29 those those DT 50458 311 30 substances substance NNS 50458 311 31 which which WDT 50458 311 32 neutralize neutralize VBP 50458 311 33 the the DT 50458 311 34 activity activity NN 50458 311 35 of of IN 50458 311 36 toxins toxin NNS 50458 311 37 under under IN 50458 311 38 certain certain JJ 50458 311 39 conditions condition NNS 50458 311 40 ) ) -RRB- 50458 311 41 which which WDT 50458 311 42 , , , 50458 311 43 introduced introduce VBD 50458 311 44 a a DT 50458 311 45 certain certain JJ 50458 311 46 time time NN 50458 311 47 after after IN 50458 311 48 the the DT 50458 311 49 introduction introduction NN 50458 311 50 of of IN 50458 311 51 the the DT 50458 311 52 poison poison NN 50458 311 53 , , , 50458 311 54 will will MD 50458 311 55 save save VB 50458 311 56 the the DT 50458 311 57 life life NN 50458 311 58 of of IN 50458 311 59 the the DT 50458 311 60 animal animal NN 50458 311 61 . . . 50458 312 1 They -PRON- PRP 50458 312 2 have have VBP 50458 312 3 experimented experiment VBN 50458 312 4 with with IN 50458 312 5 diphtheria diphtheria NN 50458 312 6 toxin toxin NN 50458 312 7 , , , 50458 312 8 which which WDT 50458 312 9 we -PRON- PRP 50458 312 10 will will MD 50458 312 11 study study VB 50458 312 12 later later RBR 50458 312 13 , , , 50458 312 14 and and CC 50458 312 15 they -PRON- PRP 50458 312 16 have have VBP 50458 312 17 demonstrated demonstrate VBN 50458 312 18 that that IN 50458 312 19 , , , 50458 312 20 if if IN 50458 312 21 the the DT 50458 312 22 antitoxic antitoxic NN 50458 312 23 serum serum NN 50458 312 24 be be VB 50458 312 25 introduced introduce VBN 50458 312 26 immediately immediately RB 50458 312 27 after after IN 50458 312 28 the the DT 50458 312 29 toxin toxin NN 50458 312 30 , , , 50458 312 31 a a DT 50458 312 32 dose dose NN 50458 312 33 of of IN 50458 312 34 antitoxin antitoxin NN 50458 312 35 twice twice RB 50458 312 36 as as RB 50458 312 37 large large JJ 50458 312 38 as as IN 50458 312 39 that that DT 50458 312 40 of of IN 50458 312 41 the the DT 50458 312 42 toxin toxin NN 50458 312 43 suffices suffice VBZ 50458 312 44 to to TO 50458 312 45 effect effect VB 50458 312 46 a a DT 50458 312 47 cure cure NN 50458 312 48 . . . 50458 313 1 [ [ -LRB- 50458 313 2 33 33 CD 50458 313 3 ] ] -RRB- 50458 313 4 VON VON NNP 50458 313 5 BEHRING behring NN 50458 313 6 and and CC 50458 313 7 WERNICKE WERNICKE NNP 50458 313 8 : : : 50458 313 9 Zeitschrift Zeitschrift NNP 50458 313 10 für für NN 50458 313 11 Hygiene Hygiene NNP 50458 313 12 , , , 50458 313 13 XII XII NNP 50458 313 14 . . . 50458 314 1 Eight eight CD 50458 314 2 hours hour NNS 50458 314 3 after after IN 50458 314 4 the the DT 50458 314 5 administration administration NN 50458 314 6 of of IN 50458 314 7 the the DT 50458 314 8 toxin toxin NN 50458 314 9 the the DT 50458 314 10 dose dose NN 50458 314 11 must must MD 50458 314 12 be be VB 50458 314 13 trebled treble VBN 50458 314 14 , , , 50458 314 15 while while IN 50458 314 16 after after IN 50458 314 17 thirty thirty CD 50458 314 18 - - HYPH 50458 314 19 six six CD 50458 314 20 hours hour NNS 50458 314 21 it -PRON- PRP 50458 314 22 is be VBZ 50458 314 23 necessary necessary JJ 50458 314 24 to to TO 50458 314 25 have have VB 50458 314 26 recourse recourse VBN 50458 314 27 to to IN 50458 314 28 a a DT 50458 314 29 quantity quantity NN 50458 314 30 of of IN 50458 314 31 antitoxin antitoxin NN 50458 314 32 eight eight CD 50458 314 33 times time NNS 50458 314 34 as as RB 50458 314 35 great great JJ 50458 314 36 . . . 50458 315 1 These these DT 50458 315 2 experiments experiment NNS 50458 315 3 show show VBP 50458 315 4 that that IN 50458 315 5 the the DT 50458 315 6 curative curative JJ 50458 315 7 action action NN 50458 315 8 of of IN 50458 315 9 the the DT 50458 315 10 antitoxin antitoxin NN 50458 315 11 is be VBZ 50458 315 12 so so RB 50458 315 13 much much RB 50458 315 14 the the DT 50458 315 15 less less RBR 50458 315 16 the the DT 50458 315 17 longer long JJR 50458 315 18 the the DT 50458 315 19 period period NN 50458 315 20 of of IN 50458 315 21 time time NN 50458 315 22 that that WDT 50458 315 23 has have VBZ 50458 315 24 elapsed elapse VBN 50458 315 25 between between IN 50458 315 26 the the DT 50458 315 27 introduction introduction NN 50458 315 28 of of IN 50458 315 29 the the DT 50458 315 30 toxin toxin NN 50458 315 31 and and CC 50458 315 32 the the DT 50458 315 33 antitoxin antitoxin NN 50458 315 34 . . . 50458 316 1 This this DT 50458 316 2 is be VBZ 50458 316 3 because because IN 50458 316 4 the the DT 50458 316 5 toxin toxin NN 50458 316 6 has have VBZ 50458 316 7 become become VBN 50458 316 8 so so RB 50458 316 9 intimately intimately RB 50458 316 10 attached attach VBN 50458 316 11 to to IN 50458 316 12 the the DT 50458 316 13 tissues tissue NNS 50458 316 14 that that WDT 50458 316 15 the the DT 50458 316 16 antitoxin antitoxin NN 50458 316 17 introduced introduce VBN 50458 316 18 has have VBZ 50458 316 19 not not RB 50458 316 20 the the DT 50458 316 21 power power NN 50458 316 22 to to TO 50458 316 23 destroy destroy VB 50458 316 24 the the DT 50458 316 25 combination combination NN 50458 316 26 . . . 50458 317 1 These these DT 50458 317 2 facts fact NNS 50458 317 3 have have VBP 50458 317 4 been be VBN 50458 317 5 confirmed confirm VBN 50458 317 6 by by IN 50458 317 7 Donitz[34 donitz[34 ADD 50458 317 8 ] ] -RRB- 50458 317 9 and and CC 50458 317 10 by by IN 50458 317 11 the the DT 50458 317 12 classic classic JJ 50458 317 13 experiments experiment NNS 50458 317 14 of of IN 50458 317 15 Decroly Decroly NNP 50458 317 16 and and CC 50458 317 17 Rousse Rousse NNP 50458 317 18 . . . 50458 318 1 [ [ -LRB- 50458 318 2 35 35 CD 50458 318 3 ] ] -RRB- 50458 318 4 [ [ -LRB- 50458 318 5 34 34 CD 50458 318 6 ] ] -RRB- 50458 318 7 DONITZ DONITZ NNP 50458 318 8 : : : 50458 318 9 Ueber Ueber NNP 50458 318 10 die die VB 50458 318 11 Grenzen Grenzen NNP 50458 318 12 der der IN 50458 318 13 Wirksamkeit Wirksamkeit NNP 50458 318 14 des des NNP 50458 318 15 Diphtheria Diphtheria NNP 50458 318 16 Heilserums Heilserums NNP 50458 318 17 . . . 50458 319 1 _ _ NNP 50458 319 2 Deutsche Deutsche NNP 50458 319 3 Med Med NNP 50458 319 4 . . . 50458 320 1 Woch Woch NNP 50458 320 2 . . . 50458 320 3 _ _ NNP 50458 320 4 , , , 50458 320 5 No no UH 50458 320 6 . . . 50458 321 1 27 27 CD 50458 321 2 , , , 50458 321 3 1897 1897 CD 50458 321 4 . . . 50458 322 1 [ [ -LRB- 50458 322 2 35 35 CD 50458 322 3 ] ] -RRB- 50458 322 4 DECROLY DECROLY NNP 50458 322 5 et et NN 50458 322 6 ROUSSE ROUSSE NNS 50458 322 7 : : : 50458 322 8 _ _ NNP 50458 322 9 Arch Arch NNP 50458 322 10 . . . 50458 323 1 Int Int NNP 50458 323 2 . . . 50458 324 1 de de NNP 50458 324 2 Pharmacodyn Pharmacodyn NNP 50458 324 3 . . . 50458 324 4 _ _ NNP 50458 324 5 , , , 50458 324 6 III III NNP 50458 324 7 and and CC 50458 324 8 VI VI NNP 50458 324 9 ; ; : 50458 324 10 Masoin Masoin NNP 50458 324 11 : : : 50458 324 12 _ _ NNP 50458 324 13 Arch Arch NNP 50458 324 14 . . . 50458 325 1 Intern intern NN 50458 325 2 . . . 50458 326 1 de de NNP 50458 326 2 Pharmacodyn Pharmacodyn NNP 50458 326 3 . . . 50458 326 4 _ _ NNP 50458 326 5 , , , 50458 326 6 II II NNP 50458 326 7 , , , 50458 326 8 1903 1903 CD 50458 326 9 . . . 50458 327 1 This this DT 50458 327 2 is be VBZ 50458 327 3 not not RB 50458 327 4 , , , 50458 327 5 however however RB 50458 327 6 , , , 50458 327 7 the the DT 50458 327 8 case case NN 50458 327 9 with with IN 50458 327 10 cold cold JJ 50458 327 11 - - HYPH 50458 327 12 blooded blooded JJ 50458 327 13 animals animal NNS 50458 327 14 , , , 50458 327 15 which which WDT 50458 327 16 , , , 50458 327 17 generally generally RB 50458 327 18 , , , 50458 327 19 are be VBP 50458 327 20 not not RB 50458 327 21 affected affect VBN 50458 327 22 by by IN 50458 327 23 injections injection NNS 50458 327 24 of of IN 50458 327 25 poisonous poisonous JJ 50458 327 26 toxins toxin NNS 50458 327 27 . . . 50458 328 1 Thus thus RB 50458 328 2 Metchnikoff[36 metchnikoff[36 ADD 50458 328 3 ] ] -RRB- 50458 328 4 and and CC 50458 328 5 his -PRON- PRP$ 50458 328 6 pupils pupil NNS 50458 328 7 have have VBP 50458 328 8 been be VBN 50458 328 9 able able JJ 50458 328 10 to to TO 50458 328 11 show show VB 50458 328 12 that that IN 50458 328 13 the the DT 50458 328 14 toxins toxin NNS 50458 328 15 introduced introduce VBN 50458 328 16 into into IN 50458 328 17 certain certain JJ 50458 328 18 cold cold JJ 50458 328 19 - - HYPH 50458 328 20 blooded blooded JJ 50458 328 21 animals animal NNS 50458 328 22 ( ( -LRB- 50458 328 23 Oryetes Oryetes NNP 50458 328 24 nasicorius nasicorius NN 50458 328 25 ) ) -RRB- 50458 328 26 may may MD 50458 328 27 remain remain VB 50458 328 28 for for IN 50458 328 29 several several JJ 50458 328 30 months month NNS 50458 328 31 without without IN 50458 328 32 alteration alteration NN 50458 328 33 in in IN 50458 328 34 their -PRON- PRP$ 50458 328 35 circulation circulation NN 50458 328 36 . . . 50458 329 1 [ [ -LRB- 50458 329 2 36 36 CD 50458 329 3 ] ] -RRB- 50458 329 4 METCHNIKOFF METCHNIKOFF NNP 50458 329 5 : : : 50458 329 6 _ _ NNP 50458 329 7 L'Immunité L'Immunité NNP 50458 329 8 _ _ NNP 50458 329 9 , , , 50458 329 10 Paris Paris NNP 50458 329 11 , , , 50458 329 12 1902 1902 CD 50458 329 13 ; ; : 50458 329 14 MORGENROTH morgenroth NN 50458 329 15 : : : 50458 329 16 Zur Zur NNP 50458 329 17 Kenntniss Kenntniss NNP 50458 329 18 des des NNP 50458 329 19 Tetanus Tetanus NNP 50458 329 20 des des FW 50458 329 21 Frosches Frosches NNP 50458 329 22 . . . 50458 330 1 _ _ NNP 50458 330 2 Deutsche Deutsche NNP 50458 330 3 Med Med NNP 50458 330 4 . . . 50458 331 1 Woch Woch NNP 50458 331 2 . . . 50458 331 3 _ _ NNP 50458 331 4 , , , 50458 331 5 No no UH 50458 331 6 . . . 50458 332 1 35 35 CD 50458 332 2 , , , 50458 332 3 1898 1898 CD 50458 332 4 . . . 50458 333 1 If if IN 50458 333 2 we -PRON- PRP 50458 333 3 consider consider VBP 50458 333 4 the the DT 50458 333 5 facts fact NNS 50458 333 6 of of IN 50458 333 7 the the DT 50458 333 8 theory theory NN 50458 333 9 of of IN 50458 333 10 Ehrlich Ehrlich NNP 50458 333 11 's 's POS 50458 333 12 lateral lateral JJ 50458 333 13 chains chain NNS 50458 333 14 , , , 50458 333 15 which which WDT 50458 333 16 we -PRON- PRP 50458 333 17 have have VBP 50458 333 18 mentioned mention VBN 50458 333 19 , , , 50458 333 20 we -PRON- PRP 50458 333 21 are be VBP 50458 333 22 led lead VBN 50458 333 23 to to IN 50458 333 24 well well RB 50458 333 25 - - HYPH 50458 333 26 defined define VBN 50458 333 27 conclusions conclusion NNS 50458 333 28 regarding regard VBG 50458 333 29 the the DT 50458 333 30 mode mode NN 50458 333 31 of of IN 50458 333 32 action action NN 50458 333 33 of of IN 50458 333 34 the the DT 50458 333 35 toxins toxin NNS 50458 333 36 . . . 50458 334 1 In in IN 50458 334 2 fact fact NN 50458 334 3 , , , 50458 334 4 since since IN 50458 334 5 these these DT 50458 334 6 toxins toxin NNS 50458 334 7 exhibit exhibit VBP 50458 334 8 a a DT 50458 334 9 pronounced pronounced JJ 50458 334 10 chemical chemical NN 50458 334 11 affinity affinity NN 50458 334 12 for for IN 50458 334 13 the the DT 50458 334 14 tissues tissue NNS 50458 334 15 , , , 50458 334 16 and and CC 50458 334 17 while while IN 50458 334 18 , , , 50458 334 19 on on IN 50458 334 20 the the DT 50458 334 21 other other JJ 50458 334 22 hand hand NN 50458 334 23 , , , 50458 334 24 they -PRON- PRP 50458 334 25 can can MD 50458 334 26 attach attach VB 50458 334 27 themselves -PRON- PRP 50458 334 28 only only RB 50458 334 29 because because IN 50458 334 30 of of IN 50458 334 31 the the DT 50458 334 32 presence presence NN 50458 334 33 of of IN 50458 334 34 certain certain JJ 50458 334 35 functional functional JJ 50458 334 36 groups group NNS 50458 334 37 of of IN 50458 334 38 the the DT 50458 334 39 protoplasmic protoplasmic NNP 50458 334 40 molecules molecule NNS 50458 334 41 , , , 50458 334 42 this this DT 50458 334 43 union union NN 50458 334 44 can can MD 50458 334 45 take take VB 50458 334 46 place place NN 50458 334 47 only only RB 50458 334 48 in in IN 50458 334 49 certain certain JJ 50458 334 50 specific specific JJ 50458 334 51 centers center NNS 50458 334 52 . . . 50458 335 1 This this DT 50458 335 2 has have VBZ 50458 335 3 been be VBN 50458 335 4 fully fully RB 50458 335 5 confirmed confirm VBN 50458 335 6 by by IN 50458 335 7 experiments experiment NNS 50458 335 8 _ _ NNP 50458 335 9 in in IN 50458 335 10 vitro vitro FW 50458 335 11 _ _ NNP 50458 335 12 . . . 50458 336 1 It -PRON- PRP 50458 336 2 is be VBZ 50458 336 3 known know VBN 50458 336 4 , , , 50458 336 5 since since IN 50458 336 6 the the DT 50458 336 7 researches research NNS 50458 336 8 of of IN 50458 336 9 Ehrlich,[37 Ehrlich,[37 NNP 50458 336 10 ] ] -RRB- 50458 336 11 Wassermann Wassermann NNP 50458 336 12 and and CC 50458 336 13 Takaki,[38 Takaki,[38 NNP 50458 336 14 ] ] -RRB- 50458 336 15 Marie,[39 Marie,[39 NNP 50458 336 16 ] ] -RRB- 50458 336 17 Metchnikoff,[40 Metchnikoff,[40 NNP 50458 336 18 ] ] -RRB- 50458 336 19 and and CC 50458 336 20 a a DT 50458 336 21 host host NN 50458 336 22 of of IN 50458 336 23 other other JJ 50458 336 24 scientists scientist NNS 50458 336 25 , , , 50458 336 26 that that IN 50458 336 27 this this DT 50458 336 28 fixation fixation NN 50458 336 29 is be VBZ 50458 336 30 due due JJ 50458 336 31 to to IN 50458 336 32 a a DT 50458 336 33 clearly clearly RB 50458 336 34 elective elective JJ 50458 336 35 property property NN 50458 336 36 . . . 50458 337 1 It -PRON- PRP 50458 337 2 is be VBZ 50458 337 3 for for IN 50458 337 4 this this DT 50458 337 5 reason reason NN 50458 337 6 that that IN 50458 337 7 the the DT 50458 337 8 tetanus tetanus NNP 50458 337 9 toxin toxin NN 50458 337 10 fixes fix VBZ 50458 337 11 itself -PRON- PRP 50458 337 12 only only RB 50458 337 13 upon upon IN 50458 337 14 the the DT 50458 337 15 nervous nervous JJ 50458 337 16 tissue tissue NN 50458 337 17 , , , 50458 337 18 and and CC 50458 337 19 that that IN 50458 337 20 in in IN 50458 337 21 this this DT 50458 337 22 action action NN 50458 337 23 all all DT 50458 337 24 passes pass VBZ 50458 337 25 as as IN 50458 337 26 if if IN 50458 337 27 the the DT 50458 337 28 nervous nervous JJ 50458 337 29 tissue tissue NN 50458 337 30 had have VBD 50458 337 31 been be VBN 50458 337 32 provided provide VBN 50458 337 33 with with IN 50458 337 34 functional functional JJ 50458 337 35 groups group NNS 50458 337 36 possessing possess VBG 50458 337 37 an an DT 50458 337 38 elective elective JJ 50458 337 39 affinity affinity NN 50458 337 40 for for IN 50458 337 41 the the DT 50458 337 42 tetanic tetanic JJ 50458 337 43 poison poison NN 50458 337 44 . . . 50458 338 1 [ [ -LRB- 50458 338 2 37 37 CD 50458 338 3 ] ] -RRB- 50458 338 4 EHRLICH ehrlich NN 50458 338 5 : : : 50458 338 6 _ _ NNP 50458 338 7 Berl Berl NNP 50458 338 8 . . . 50458 339 1 Klin Klin NNP 50458 339 2 . . . 50458 340 1 Woch Woch NNP 50458 340 2 . . . 50458 340 3 _ _ NNP 50458 340 4 , , , 50458 340 5 No no UH 50458 340 6 . . . 50458 341 1 12 12 CD 50458 341 2 , , , 50458 341 3 1898 1898 CD 50458 341 4 . . . 50458 342 1 [ [ -LRB- 50458 342 2 38 38 CD 50458 342 3 ] ] -RRB- 50458 342 4 WASSERMANN wassermann NN 50458 342 5 and and CC 50458 342 6 TAKAKI takaki NN 50458 342 7 : : : 50458 342 8 _ _ NNP 50458 342 9 Berl Berl NNP 50458 342 10 . . . 50458 343 1 Klin Klin NNP 50458 343 2 . . . 50458 344 1 Woch Woch NNP 50458 344 2 . . . 50458 344 3 _ _ NNP 50458 344 4 , , , 50458 344 5 _ _ NNP 50458 344 6 Med Med NNP 50458 344 7 . . . 50458 344 8 _ _ NNP 50458 344 9 , , , 50458 344 10 p. p. NN 50458 344 11 5 5 CD 50458 344 12 , , , 50458 344 13 1898 1898 CD 50458 344 14 . . . 50458 345 1 [ [ -LRB- 50458 345 2 39 39 CD 50458 345 3 ] ] -RRB- 50458 345 4 MARIE MARIE NNP 50458 345 5 : : : 50458 345 6 Sur sur NN 50458 345 7 les les FW 50458 345 8 Propriétés Propriétés NNP 50458 345 9 Antitoxiques Antitoxiques NNPS 50458 345 10 aux aux NN 50458 345 11 Centres centre VBZ 50458 345 12 Nerveux Nerveux NNP 50458 345 13 de de NNP 50458 345 14 l'Animal l'Animal NNP 50458 345 15 Sain Sain NNP 50458 345 16 . . . 50458 346 1 _ _ NNP 50458 346 2 Ann Ann NNP 50458 346 3 . . . 50458 347 1 Inst inst RB 50458 347 2 . . . 50458 348 1 Past past NN 50458 348 2 . . . 50458 348 3 _ _ NNP 50458 348 4 , , , 50458 348 5 1898 1898 CD 50458 348 6 , , , 50458 348 7 p. p. NN 50458 348 8 1 1 CD 50458 348 9 . . . 50458 349 1 [ [ -LRB- 50458 349 2 40 40 CD 50458 349 3 ] ] -RRB- 50458 349 4 METCHNIKOFF metchnikoff JJ 50458 349 5 : : : 50458 349 6 Recherches recherche NNS 50458 349 7 sur sur NNP 50458 349 8 l'Influence l'Influence NNP 50458 349 9 de de NNP 50458 349 10 l'Organism l'Organism NNP 50458 349 11 sur sur FW 50458 349 12 les les NNP 50458 349 13 Toxines Toxines NNP 50458 349 14 . . . 50458 350 1 _ _ NNP 50458 350 2 Ann Ann NNP 50458 350 3 . . . 50458 351 1 Inst inst RB 50458 351 2 . . . 50458 352 1 Past past NN 50458 352 2 . . . 50458 352 3 _ _ NNP 50458 352 4 , , , 50458 352 5 1899 1899 CD 50458 352 6 , , , 50458 352 7 p. p. NN 50458 352 8 82 82 CD 50458 352 9 . . . 50458 353 1 = = NFP 50458 353 2 Means Means NNPS 50458 353 3 of of IN 50458 353 4 Defense Defense NNP 50458 353 5 Possessed possess VBN 50458 353 6 by by IN 50458 353 7 the the DT 50458 353 8 Organism Organism NNP 50458 353 9 against against IN 50458 353 10 the the DT 50458 353 11 Action Action NNP 50458 353 12 of of IN 50458 353 13 Toxins.=--We Toxins.=--We NNP 50458 353 14 have have VBP 50458 353 15 already already RB 50458 353 16 seen see VBN 50458 353 17 that that IN 50458 353 18 the the DT 50458 353 19 renal renal JJ 50458 353 20 organs organ NNS 50458 353 21 serve serve VBP 50458 353 22 for for IN 50458 353 23 the the DT 50458 353 24 elimination elimination NN 50458 353 25 of of IN 50458 353 26 the the DT 50458 353 27 toxins toxin NNS 50458 353 28 normally normally RB 50458 353 29 produced produce VBN 50458 353 30 in in IN 50458 353 31 the the DT 50458 353 32 organism organism NN 50458 353 33 by by IN 50458 353 34 the the DT 50458 353 35 simple simple JJ 50458 353 36 play play NN 50458 353 37 of of IN 50458 353 38 its -PRON- PRP$ 50458 353 39 cellular cellular JJ 50458 353 40 mechanism mechanism NN 50458 353 41 . . . 50458 354 1 Experience experience NN 50458 354 2 has have VBZ 50458 354 3 shown show VBN 50458 354 4 that that IN 50458 354 5 the the DT 50458 354 6 toxins toxin NNS 50458 354 7 introduced introduce VBN 50458 354 8 from from IN 50458 354 9 without without IN 50458 354 10 into into IN 50458 354 11 the the DT 50458 354 12 circulation circulation NN 50458 354 13 are be VBP 50458 354 14 generally generally RB 50458 354 15 finally finally RB 50458 354 16 eliminated eliminate VBN 50458 354 17 , , , 50458 354 18 even even RB 50458 354 19 though though IN 50458 354 20 in in IN 50458 354 21 the the DT 50458 354 22 meantime meantime NN 50458 354 23 the the DT 50458 354 24 modifications modification NNS 50458 354 25 they -PRON- PRP 50458 354 26 have have VBP 50458 354 27 imprinted imprint VBN 50458 354 28 on on IN 50458 354 29 the the DT 50458 354 30 economy economy NN 50458 354 31 may may MD 50458 354 32 be be VB 50458 354 33 transmitted transmit VBN 50458 354 34 hereditarily hereditarily RB 50458 354 35 ; ; : 50458 354 36 and and CC 50458 354 37 that that IN 50458 354 38 their -PRON- PRP$ 50458 354 39 influence influence NN 50458 354 40 on on IN 50458 354 41 the the DT 50458 354 42 general general JJ 50458 354 43 nutrition nutrition NN 50458 354 44 and and CC 50458 354 45 the the DT 50458 354 46 normal normal JJ 50458 354 47 functionation functionation NN 50458 354 48 of of IN 50458 354 49 the the DT 50458 354 50 entire entire JJ 50458 354 51 organism organism NN 50458 354 52 persists persist VBZ 50458 354 53 even even RB 50458 354 54 after after IN 50458 354 55 their -PRON- PRP$ 50458 354 56 elimination elimination NN 50458 354 57 . . . 50458 355 1 Much much JJ 50458 355 2 has have VBZ 50458 355 3 been be VBN 50458 355 4 said say VBN 50458 355 5 regarding regard VBG 50458 355 6 the the DT 50458 355 7 elimination elimination NN 50458 355 8 of of IN 50458 355 9 these these DT 50458 355 10 toxins toxin NNS 50458 355 11 by by IN 50458 355 12 the the DT 50458 355 13 urine urine NN 50458 355 14 , , , 50458 355 15 but but CC 50458 355 16 the the DT 50458 355 17 experiments experiment NNS 50458 355 18 made make VBN 50458 355 19 by by IN 50458 355 20 Métin Métin NNP 50458 355 21 , , , 50458 355 22 at at IN 50458 355 23 the the DT 50458 355 24 Institut Institut NNP 50458 355 25 Pasteur Pasteur NNP 50458 355 26 , , , 50458 355 27 have have VBP 50458 355 28 shown show VBN 50458 355 29 the the DT 50458 355 30 inaccuracy inaccuracy NN 50458 355 31 of of IN 50458 355 32 this this DT 50458 355 33 assumption assumption NN 50458 355 34 , , , 50458 355 35 and and CC 50458 355 36 it -PRON- PRP 50458 355 37 has have VBZ 50458 355 38 been be VBN 50458 355 39 necessary necessary JJ 50458 355 40 to to TO 50458 355 41 seek seek VB 50458 355 42 another another DT 50458 355 43 . . . 50458 356 1 It -PRON- PRP 50458 356 2 has have VBZ 50458 356 3 been be VBN 50458 356 4 remarked remark VBN 50458 356 5 that that IN 50458 356 6 oxidation oxidation NN 50458 356 7 destroys destroy VBZ 50458 356 8 the the DT 50458 356 9 toxins toxin NNS 50458 356 10 _ _ NNP 50458 356 11 in in IN 50458 356 12 vitro vitro FW 50458 356 13 _ _ NNP 50458 356 14 , , , 50458 356 15 and and CC 50458 356 16 it -PRON- PRP 50458 356 17 has have VBZ 50458 356 18 been be VBN 50458 356 19 thought think VBN 50458 356 20 that that IN 50458 356 21 a a DT 50458 356 22 process process NN 50458 356 23 resembling resemble VBG 50458 356 24 disinfection disinfection NN 50458 356 25 may may MD 50458 356 26 well well RB 50458 356 27 take take VB 50458 356 28 place place NN 50458 356 29 within within IN 50458 356 30 the the DT 50458 356 31 tissues tissue NNS 50458 356 32 of of IN 50458 356 33 the the DT 50458 356 34 animal animal NN 50458 356 35 economy economy NN 50458 356 36 , , , 50458 356 37 but but CC 50458 356 38 no no DT 50458 356 39 decision decision NN 50458 356 40 has have VBZ 50458 356 41 been be VBN 50458 356 42 arrived arrive VBN 50458 356 43 at at IN 50458 356 44 regarding regard VBG 50458 356 45 the the DT 50458 356 46 possible possible JJ 50458 356 47 mechanism mechanism NN 50458 356 48 of of IN 50458 356 49 this this DT 50458 356 50 action action NN 50458 356 51 , , , 50458 356 52 which which WDT 50458 356 53 some some DT 50458 356 54 attribute attribute NN 50458 356 55 to to IN 50458 356 56 the the DT 50458 356 57 action action NN 50458 356 58 of of IN 50458 356 59 the the DT 50458 356 60 oxidizing oxidizing JJ 50458 356 61 ferments ferment NNS 50458 356 62 of of IN 50458 356 63 the the DT 50458 356 64 organism organism NN 50458 356 65 , , , 50458 356 66 or or CC 50458 356 67 to to IN 50458 356 68 the the DT 50458 356 69 action action NN 50458 356 70 of of IN 50458 356 71 certain certain JJ 50458 356 72 special special JJ 50458 356 73 cells cell NNS 50458 356 74 . . . 50458 357 1 According accord VBG 50458 357 2 to to IN 50458 357 3 Poehl Poehl NNP 50458 357 4 , , , 50458 357 5 there there EX 50458 357 6 is be VBZ 50458 357 7 developed develop VBN 50458 357 8 as as IN 50458 357 9 destroyer destroyer NN 50458 357 10 a a DT 50458 357 11 substance substance NN 50458 357 12 possessing possess VBG 50458 357 13 energetic energetic JJ 50458 357 14 oxidizing oxidizing JJ 50458 357 15 properties property NNS 50458 357 16 , , , 50458 357 17 which which WDT 50458 357 18 he -PRON- PRP 50458 357 19 has have VBZ 50458 357 20 isolated isolate VBN 50458 357 21 and and CC 50458 357 22 named name VBN 50458 357 23 _ _ NNP 50458 357 24 spermine spermine NN 50458 357 25 _ _ NNP 50458 357 26 , , , 50458 357 27 and and CC 50458 357 28 which which WDT 50458 357 29 is be VBZ 50458 357 30 found find VBN 50458 357 31 in in IN 50458 357 32 most most JJS 50458 357 33 of of IN 50458 357 34 the the DT 50458 357 35 organic organic JJ 50458 357 36 fluids fluid NNS 50458 357 37 and and CC 50458 357 38 particularly particularly RB 50458 357 39 in in IN 50458 357 40 the the DT 50458 357 41 leucocytes leucocyte NNS 50458 357 42 , , , 50458 357 43 the the DT 50458 357 44 special special JJ 50458 357 45 rôle rôle NN 50458 357 46 of of IN 50458 357 47 which which WDT 50458 357 48 we -PRON- PRP 50458 357 49 will will MD 50458 357 50 presently presently RB 50458 357 51 study study VB 50458 357 52 . . . 50458 358 1 There there EX 50458 358 2 develops develop VBZ 50458 358 3 still still RB 50458 358 4 another another DT 50458 358 5 cause cause NN 50458 358 6 of of IN 50458 358 7 elimination elimination NN 50458 358 8 , , , 50458 358 9 or or CC 50458 358 10 , , , 50458 358 11 to to TO 50458 358 12 be be VB 50458 358 13 more more RBR 50458 358 14 exact exact JJ 50458 358 15 , , , 50458 358 16 of of IN 50458 358 17 the the DT 50458 358 18 neutralization neutralization NN 50458 358 19 of of IN 50458 358 20 the the DT 50458 358 21 toxic toxic JJ 50458 358 22 principles principle NNS 50458 358 23 in in IN 50458 358 24 defense defense NN 50458 358 25 of of IN 50458 358 26 the the DT 50458 358 27 organism organism NN 50458 358 28 against against IN 50458 358 29 the the DT 50458 358 30 toxins toxin NNS 50458 358 31 , , , 50458 358 32 and and CC 50458 358 33 that that DT 50458 358 34 is be VBZ 50458 358 35 the the DT 50458 358 36 formation formation NN 50458 358 37 of of IN 50458 358 38 _ _ NNP 50458 358 39 antitoxins antitoxins NNP 50458 358 40 _ _ NNP 50458 358 41 . . . 50458 359 1 It -PRON- PRP 50458 359 2 is be VBZ 50458 359 3 well well RB 50458 359 4 known know VBN 50458 359 5 that that IN 50458 359 6 the the DT 50458 359 7 term term NN 50458 359 8 _ _ NNP 50458 359 9 virus virus NN 50458 359 10 _ _ NNP 50458 359 11 has have VBZ 50458 359 12 been be VBN 50458 359 13 reserved reserve VBN 50458 359 14 to to TO 50458 359 15 designate designate VB 50458 359 16 physiological physiological JJ 50458 359 17 liquids liquid NNS 50458 359 18 which which WDT 50458 359 19 were be VBD 50458 359 20 characterized characterize VBN 50458 359 21 , , , 50458 359 22 when when WRB 50458 359 23 first first RB 50458 359 24 they -PRON- PRP 50458 359 25 were be VBD 50458 359 26 known know VBN 50458 359 27 , , , 50458 359 28 by by IN 50458 359 29 their -PRON- PRP$ 50458 359 30 property property NN 50458 359 31 of of IN 50458 359 32 transmitting transmit VBG 50458 359 33 to to IN 50458 359 34 an an DT 50458 359 35 organism organism NN 50458 359 36 certain certain JJ 50458 359 37 functional functional JJ 50458 359 38 affections affection NNS 50458 359 39 , , , 50458 359 40 but but CC 50458 359 41 the the DT 50458 359 42 true true JJ 50458 359 43 character character NN 50458 359 44 of of IN 50458 359 45 which which WDT 50458 359 46 is be VBZ 50458 359 47 to to TO 50458 359 48 expend expend VB 50458 359 49 their -PRON- PRP$ 50458 359 50 toxicity toxicity NN 50458 359 51 upon upon IN 50458 359 52 the the DT 50458 359 53 microbes microbe NNS 50458 359 54 which which WDT 50458 359 55 occur occur VBP 50458 359 56 and and CC 50458 359 57 are be VBP 50458 359 58 reproduced reproduce VBN 50458 359 59 in in IN 50458 359 60 the the DT 50458 359 61 organism organism NN 50458 359 62 , , , 50458 359 63 or or CC 50458 359 64 upon upon IN 50458 359 65 the the DT 50458 359 66 organized organize VBN 50458 359 67 plastidulary plastidulary JJ 50458 359 68 granulations granulation NNS 50458 359 69 , , , 50458 359 70 as as IN 50458 359 71 in in IN 50458 359 72 the the DT 50458 359 73 case case NN 50458 359 74 of of IN 50458 359 75 the the DT 50458 359 76 rabic rabic JJ 50458 359 77 virus virus NN 50458 359 78 , , , 50458 359 79 the the DT 50458 359 80 special special JJ 50458 359 81 microbe microbe NN 50458 359 82 of of IN 50458 359 83 which which WDT 50458 359 84 has have VBZ 50458 359 85 not not RB 50458 359 86 as as RB 50458 359 87 yet yet RB 50458 359 88 been be VBN 50458 359 89 isolated isolate VBN 50458 359 90 . . . 50458 360 1 Pasteur Pasteur NNP 50458 360 2 , , , 50458 360 3 when when WRB 50458 360 4 studying study VBG 50458 360 5 rabies rabie NNS 50458 360 6 , , , 50458 360 7 found find VBD 50458 360 8 that that IN 50458 360 9 the the DT 50458 360 10 brain brain NN 50458 360 11 and and CC 50458 360 12 spinal spinal JJ 50458 360 13 marrow marrow NN 50458 360 14 of of IN 50458 360 15 rabid rabid JJ 50458 360 16 animals animal NNS 50458 360 17 contained contain VBD 50458 360 18 the the DT 50458 360 19 pure pure JJ 50458 360 20 rabic rabic NN 50458 360 21 virus virus NN 50458 360 22 in in IN 50458 360 23 considerable considerable JJ 50458 360 24 quantity quantity NN 50458 360 25 , , , 50458 360 26 and and CC 50458 360 27 that that IN 50458 360 28 every every DT 50458 360 29 particle particle NN 50458 360 30 of of IN 50458 360 31 the the DT 50458 360 32 marrow marrow NN 50458 360 33 was be VBD 50458 360 34 capable capable JJ 50458 360 35 of of IN 50458 360 36 imparting impart VBG 50458 360 37 rabies rabie NNS 50458 360 38 to to IN 50458 360 39 a a DT 50458 360 40 perfectly perfectly RB 50458 360 41 healthy healthy JJ 50458 360 42 dog dog NN 50458 360 43 . . . 50458 361 1 After after IN 50458 361 2 having have VBG 50458 361 3 ascertained ascertain VBN 50458 361 4 this this DT 50458 361 5 fact fact NN 50458 361 6 , , , 50458 361 7 he -PRON- PRP 50458 361 8 found find VBD 50458 361 9 that that IN 50458 361 10 he -PRON- PRP 50458 361 11 could could MD 50458 361 12 _ _ NNP 50458 361 13 attenuate attenuate VB 50458 361 14 the the DT 50458 361 15 action action NN 50458 361 16 of of IN 50458 361 17 the the DT 50458 361 18 virus virus NN 50458 361 19 _ _ NNP 50458 361 20 , , , 50458 361 21 either either CC 50458 361 22 by by IN 50458 361 23 passing pass VBG 50458 361 24 the the DT 50458 361 25 virus virus NN 50458 361 26 through through IN 50458 361 27 certain certain JJ 50458 361 28 animal animal NN 50458 361 29 organisms organism NNS 50458 361 30 , , , 50458 361 31 such such JJ 50458 361 32 as as IN 50458 361 33 the the DT 50458 361 34 monkey monkey NN 50458 361 35 or or CC 50458 361 36 rabbit rabbit NN 50458 361 37 , , , 50458 361 38 by by IN 50458 361 39 gently gently RB 50458 361 40 heating heating NN 50458 361 41 , , , 50458 361 42 or or CC 50458 361 43 even even RB 50458 361 44 by by IN 50458 361 45 allowing allow VBG 50458 361 46 it -PRON- PRP 50458 361 47 to to TO 50458 361 48 oxidize oxidize VB 50458 361 49 and and CC 50458 361 50 partially partially RB 50458 361 51 dry dry JJ 50458 361 52 in in IN 50458 361 53 the the DT 50458 361 54 air air NN 50458 361 55 , , , 50458 361 56 or or CC 50458 361 57 else else RB 50458 361 58 by by IN 50458 361 59 submitting submit VBG 50458 361 60 it -PRON- PRP 50458 361 61 to to IN 50458 361 62 the the DT 50458 361 63 action action NN 50458 361 64 of of IN 50458 361 65 antiseptics antiseptic NNS 50458 361 66 or or CC 50458 361 67 alternating alternate VBG 50458 361 68 electric electric JJ 50458 361 69 currents current NNS 50458 361 70 of of IN 50458 361 71 very very RB 50458 361 72 high high JJ 50458 361 73 tension tension NN 50458 361 74 . . . 50458 362 1 Experiments experiment NNS 50458 362 2 have have VBP 50458 362 3 shown show VBN 50458 362 4 that that IN 50458 362 5 a a DT 50458 362 6 deadly deadly JJ 50458 362 7 virus virus NN 50458 362 8 , , , 50458 362 9 attenuated attenuate VBN 50458 362 10 by by IN 50458 362 11 one one CD 50458 362 12 of of IN 50458 362 13 the the DT 50458 362 14 means mean NNS 50458 362 15 mentioned mention VBN 50458 362 16 , , , 50458 362 17 may may MD 50458 362 18 be be VB 50458 362 19 injected inject VBN 50458 362 20 , , , 50458 362 21 without without IN 50458 362 22 danger danger NN 50458 362 23 of of IN 50458 362 24 death death NN 50458 362 25 , , , 50458 362 26 into into IN 50458 362 27 the the DT 50458 362 28 living living NN 50458 362 29 animal animal NN 50458 362 30 ; ; : 50458 362 31 and and CC 50458 362 32 what what WP 50458 362 33 is be VBZ 50458 362 34 still still RB 50458 362 35 better well JJR 50458 362 36 , , , 50458 362 37 the the DT 50458 362 38 animal animal NN 50458 362 39 thus thus RB 50458 362 40 treated treat VBD 50458 362 41 acquires acquire VBZ 50458 362 42 the the DT 50458 362 43 power power NN 50458 362 44 of of IN 50458 362 45 resisting resist VBG 50458 362 46 large large JJ 50458 362 47 doses dose NNS 50458 362 48 of of IN 50458 362 49 the the DT 50458 362 50 virus virus NN 50458 362 51 , , , 50458 362 52 less less JJR 50458 362 53 and and CC 50458 362 54 less less RBR 50458 362 55 attenuated attenuated JJ 50458 362 56 , , , 50458 362 57 and and CC 50458 362 58 that that IN 50458 362 59 it -PRON- PRP 50458 362 60 is be VBZ 50458 362 61 possible possible JJ 50458 362 62 to to TO 50458 362 63 reach reach VB 50458 362 64 a a DT 50458 362 65 point point NN 50458 362 66 where where WRB 50458 362 67 the the DT 50458 362 68 animal animal NN 50458 362 69 economy economy NN 50458 362 70 may may MD 50458 362 71 become become VB 50458 362 72 habituated habituated JJ 50458 362 73 to to IN 50458 362 74 very very RB 50458 362 75 large large JJ 50458 362 76 doses dose NNS 50458 362 77 of of IN 50458 362 78 a a DT 50458 362 79 highly highly RB 50458 362 80 virulent virulent JJ 50458 362 81 virus virus NN 50458 362 82 without without IN 50458 362 83 the the DT 50458 362 84 organism organism NN 50458 362 85 experiencing experience VBG 50458 362 86 any any DT 50458 362 87 visible visible JJ 50458 362 88 illness illness NN 50458 362 89 -- -- : 50458 362 90 that that RB 50458 362 91 is is RB 50458 362 92 , , , 50458 362 93 the the DT 50458 362 94 organism organism NN 50458 362 95 has have VBZ 50458 362 96 been be VBN 50458 362 97 _ _ NNP 50458 362 98 vaccinated vaccinate VBN 50458 362 99 _ _ NNP 50458 362 100 with with IN 50458 362 101 regard regard NN 50458 362 102 to to IN 50458 362 103 the the DT 50458 362 104 particular particular JJ 50458 362 105 virus virus NN 50458 362 106 . . . 50458 363 1 Experiments experiment NNS 50458 363 2 have have VBP 50458 363 3 shown show VBN 50458 363 4 that that IN 50458 363 5 this this DT 50458 363 6 property property NN 50458 363 7 is be VBZ 50458 363 8 not not RB 50458 363 9 peculiar peculiar JJ 50458 363 10 to to IN 50458 363 11 microbial microbial JJ 50458 363 12 virus virus NN 50458 363 13 alone alone RB 50458 363 14 , , , 50458 363 15 but but CC 50458 363 16 that that IN 50458 363 17 it -PRON- PRP 50458 363 18 is be VBZ 50458 363 19 common common JJ 50458 363 20 to to IN 50458 363 21 the the DT 50458 363 22 venoms venom NNS 50458 363 23 the the DT 50458 363 24 toxicity toxicity NN 50458 363 25 of of IN 50458 363 26 which which WDT 50458 363 27 is be VBZ 50458 363 28 essentially essentially RB 50458 363 29 due due JJ 50458 363 30 to to IN 50458 363 31 some some DT 50458 363 32 toxins toxin NNS 50458 363 33 , , , 50458 363 34 with with IN 50458 363 35 the the DT 50458 363 36 exception exception NN 50458 363 37 of of IN 50458 363 38 those those DT 50458 363 39 agents agent NNS 50458 363 40 noted note VBD 50458 363 41 . . . 50458 364 1 The the DT 50458 364 2 attenuated attenuate VBN 50458 364 3 viruses virus NNS 50458 364 4 act act NNP 50458 364 5 , , , 50458 364 6 as as IN 50458 364 7 vaccins vaccin NNS 50458 364 8 , , , 50458 364 9 through through IN 50458 364 10 their -PRON- PRP$ 50458 364 11 soluble soluble JJ 50458 364 12 constituents constituent NNS 50458 364 13 , , , 50458 364 14 which which WDT 50458 364 15 , , , 50458 364 16 either either CC 50458 364 17 directly directly RB 50458 364 18 , , , 50458 364 19 by by IN 50458 364 20 modifying modify VBG 50458 364 21 the the DT 50458 364 22 nutrition nutrition NN 50458 364 23 of of IN 50458 364 24 certain certain JJ 50458 364 25 cells cell NNS 50458 364 26 , , , 50458 364 27 or or CC 50458 364 28 indirectly indirectly RB 50458 364 29 , , , 50458 364 30 by by IN 50458 364 31 inducing induce VBG 50458 364 32 reactions reaction NNS 50458 364 33 of of IN 50458 364 34 the the DT 50458 364 35 nervous nervous JJ 50458 364 36 centers center NNS 50458 364 37 which which WDT 50458 364 38 preside preside VBP 50458 364 39 over over IN 50458 364 40 this this DT 50458 364 41 nutrition nutrition NN 50458 364 42 , , , 50458 364 43 profoundly profoundly RB 50458 364 44 change change VBP 50458 364 45 the the DT 50458 364 46 conditions condition NNS 50458 364 47 of of IN 50458 364 48 life life NN 50458 364 49 and and CC 50458 364 50 give give VB 50458 364 51 rise rise NN 50458 364 52 to to IN 50458 364 53 the the DT 50458 364 54 pathological pathological JJ 50458 364 55 condition condition NN 50458 364 56 -- -- : 50458 364 57 the the DT 50458 364 58 vaccined vaccined JJ 50458 364 59 state state NN 50458 364 60 . . . 50458 365 1 Experiments experiment NNS 50458 365 2 by by IN 50458 365 3 Behring behre VBG 50458 365 4 and and CC 50458 365 5 Kitasato[41 Kitasato[41 NNP 50458 365 6 ] ] -RRB- 50458 365 7 have have VBP 50458 365 8 shown show VBN 50458 365 9 that that IN 50458 365 10 the the DT 50458 365 11 tumors tumor NNS 50458 365 12 of of IN 50458 365 13 a a DT 50458 365 14 vaccinated vaccinated JJ 50458 365 15 animal animal NN 50458 365 16 , , , 50458 365 17 freed free VBN 50458 365 18 from from IN 50458 365 19 all all DT 50458 365 20 organized organized JJ 50458 365 21 matter matter NN 50458 365 22 visible visible JJ 50458 365 23 under under IN 50458 365 24 the the DT 50458 365 25 microscope microscope NN 50458 365 26 by by IN 50458 365 27 filtration filtration NN 50458 365 28 through through IN 50458 365 29 porcelain porcelain NN 50458 365 30 , , , 50458 365 31 contains contain VBZ 50458 365 32 principles principle NNS 50458 365 33 capable capable JJ 50458 365 34 of of IN 50458 365 35 directly directly RB 50458 365 36 or or CC 50458 365 37 indirectly indirectly RB 50458 365 38 protecting protect VBG 50458 365 39 other other JJ 50458 365 40 animals animal NNS 50458 365 41 from from IN 50458 365 42 the the DT 50458 365 43 disease disease NN 50458 365 44 caused cause VBN 50458 365 45 by by IN 50458 365 46 the the DT 50458 365 47 corresponding correspond VBG 50458 365 48 virus virus NN 50458 365 49 . . . 50458 366 1 Meanwhile meanwhile RB 50458 366 2 , , , 50458 366 3 experiments experiment NNS 50458 366 4 have have VBP 50458 366 5 shown show VBN 50458 366 6 that that IN 50458 366 7 the the DT 50458 366 8 vaccinating vaccinating NN 50458 366 9 matters matter NNS 50458 366 10 are be VBP 50458 366 11 totally totally RB 50458 366 12 eliminated eliminate VBN 50458 366 13 ; ; : 50458 366 14 nevertheless nevertheless RB 50458 366 15 , , , 50458 366 16 after after IN 50458 366 17 their -PRON- PRP$ 50458 366 18 elimination elimination NN 50458 366 19 , , , 50458 366 20 the the DT 50458 366 21 immunity immunity NN 50458 366 22 acquired acquire VBD 50458 366 23 remains remain VBZ 50458 366 24 with with IN 50458 366 25 the the DT 50458 366 26 animal animal NN 50458 366 27 , , , 50458 366 28 which which WDT 50458 366 29 then then RB 50458 366 30 continues continue VBZ 50458 366 31 to to TO 50458 366 32 be be VB 50458 366 33 protected protect VBN 50458 366 34 against against IN 50458 366 35 the the DT 50458 366 36 corresponding correspond VBG 50458 366 37 virus virus NN 50458 366 38 . . . 50458 367 1 [ [ -LRB- 50458 367 2 41 41 CD 50458 367 3 ] ] -RRB- 50458 367 4 _ _ NNP 50458 367 5 Deutsche Deutsche NNP 50458 367 6 Med Med NNP 50458 367 7 . . . 50458 368 1 Wochenschr Wochenschr NNP 50458 368 2 . . . 50458 368 3 _ _ NNP 50458 368 4 , , , 50458 368 5 1890 1890 CD 50458 368 6 , , , 50458 368 7 p. p. NN 50458 368 8 1113 1113 CD 50458 368 9 . . . 50458 369 1 Interest interest NN 50458 369 2 in in IN 50458 369 3 this this DT 50458 369 4 subject subject NN 50458 369 5 has have VBZ 50458 369 6 incited incite VBN 50458 369 7 numerous numerous JJ 50458 369 8 researches research NNS 50458 369 9 with with IN 50458 369 10 a a DT 50458 369 11 regard regard NN 50458 369 12 to to IN 50458 369 13 bringing bring VBG 50458 369 14 to to TO 50458 369 15 light light VB 50458 369 16 the the DT 50458 369 17 mechanism mechanism NN 50458 369 18 of of IN 50458 369 19 this this DT 50458 369 20 immunization immunization NN 50458 369 21 ; ; : 50458 369 22 and and CC 50458 369 23 this this DT 50458 369 24 will will MD 50458 369 25 form form VB 50458 369 26 the the DT 50458 369 27 subject subject NN 50458 369 28 of of IN 50458 369 29 another another DT 50458 369 30 volume volume NN 50458 369 31 of of IN 50458 369 32 this this DT 50458 369 33 collection collection NN 50458 369 34 . . . 50458 370 1 We -PRON- PRP 50458 370 2 may may MD 50458 370 3 state state VB 50458 370 4 here here RB 50458 370 5 , , , 50458 370 6 however however RB 50458 370 7 , , , 50458 370 8 that that IN 50458 370 9 there there EX 50458 370 10 have have VBP 50458 370 11 been be VBN 50458 370 12 recognized recognize VBN 50458 370 13 two two CD 50458 370 14 concurrent concurrent JJ 50458 370 15 causes cause NNS 50458 370 16 of of IN 50458 370 17 this this DT 50458 370 18 preservative preservative JJ 50458 370 19 action action NN 50458 370 20 ; ; : 50458 370 21 the the DT 50458 370 22 one one NN 50458 370 23 , , , 50458 370 24 called call VBD 50458 370 25 _ _ NNP 50458 370 26 phagocytosis phagocytosis NN 50458 370 27 _ _ NNP 50458 370 28 , , , 50458 370 29 results result NNS 50458 370 30 from from IN 50458 370 31 the the DT 50458 370 32 fact fact NN 50458 370 33 that that IN 50458 370 34 the the DT 50458 370 35 microbe microbe NN 50458 370 36 introduced introduce VBN 50458 370 37 into into IN 50458 370 38 the the DT 50458 370 39 vaccined vaccined JJ 50458 370 40 organism organism NN 50458 370 41 becomes become VBZ 50458 370 42 incapable incapable JJ 50458 370 43 of of IN 50458 370 44 producing produce VBG 50458 370 45 its -PRON- PRP$ 50458 370 46 usual usual JJ 50458 370 47 toxins toxin NNS 50458 370 48 , , , 50458 370 49 while while IN 50458 370 50 on on IN 50458 370 51 the the DT 50458 370 52 other other JJ 50458 370 53 hand hand NN 50458 370 54 the the DT 50458 370 55 immunization immunization NN 50458 370 56 renders render VBZ 50458 370 57 the the DT 50458 370 58 organism organism NN 50458 370 59 capable capable JJ 50458 370 60 of of IN 50458 370 61 secreting secrete VBG 50458 370 62 substances substance NNS 50458 370 63 possessing possess VBG 50458 370 64 an an DT 50458 370 65 activity activity NN 50458 370 66 contrary contrary JJ 50458 370 67 to to IN 50458 370 68 that that DT 50458 370 69 of of IN 50458 370 70 the the DT 50458 370 71 virus virus NN 50458 370 72 , , , 50458 370 73 in in IN 50458 370 74 fact fact NN 50458 370 75 true true JJ 50458 370 76 counter counter NN 50458 370 77 - - NNS 50458 370 78 poisons poison NNS 50458 370 79 , , , 50458 370 80 comprised comprise VBN 50458 370 81 under under IN 50458 370 82 the the DT 50458 370 83 general general JJ 50458 370 84 name name NN 50458 370 85 _ _ NNP 50458 370 86 antitoxins antitoxins NNP 50458 370 87 _ _ NNP 50458 370 88 . . . 50458 371 1 = = NFP 50458 371 2 Phagocytosis.=--We Phagocytosis.=--We NNP 50458 371 3 have have VBP 50458 371 4 seen see VBN 50458 371 5 that that IN 50458 371 6 an an DT 50458 371 7 organism organism NN 50458 371 8 subjected subject VBN 50458 371 9 to to IN 50458 371 10 a a DT 50458 371 11 toxic toxic JJ 50458 371 12 invasion invasion NN 50458 371 13 tends tend VBZ 50458 371 14 to to TO 50458 371 15 protect protect VB 50458 371 16 itself -PRON- PRP 50458 371 17 by by IN 50458 371 18 proper proper JJ 50458 371 19 means mean NNS 50458 371 20 of of IN 50458 371 21 defense defense NN 50458 371 22 ; ; : 50458 371 23 and and CC 50458 371 24 one one CD 50458 371 25 of of IN 50458 371 26 those those DT 50458 371 27 is be VBZ 50458 371 28 the the DT 50458 371 29 direct direct JJ 50458 371 30 putting putting NN 50458 371 31 into into IN 50458 371 32 activity activity NN 50458 371 33 of of IN 50458 371 34 the the DT 50458 371 35 living live VBG 50458 371 36 cellular cellular JJ 50458 371 37 elements element NNS 50458 371 38 themselves -PRON- PRP 50458 371 39 , , , 50458 371 40 and and CC 50458 371 41 in in IN 50458 371 42 particular particular JJ 50458 371 43 , , , 50458 371 44 the the DT 50458 371 45 leucocytes leucocyte NNS 50458 371 46 , , , 50458 371 47 or or CC 50458 371 48 white white JJ 50458 371 49 corpuscles corpuscle NNS 50458 371 50 , , , 50458 371 51 found find VBN 50458 371 52 in in IN 50458 371 53 more more JJR 50458 371 54 or or CC 50458 371 55 less less JJR 50458 371 56 number number NN 50458 371 57 , , , 50458 371 58 according accord VBG 50458 371 59 to to IN 50458 371 60 pathological pathological JJ 50458 371 61 conditions condition NNS 50458 371 62 , , , 50458 371 63 in in IN 50458 371 64 the the DT 50458 371 65 blood blood NN 50458 371 66 and and CC 50458 371 67 lymphatic lymphatic JJ 50458 371 68 fluids fluid NNS 50458 371 69 . . . 50458 372 1 [ [ -LRB- 50458 372 2 42 42 CD 50458 372 3 ] ] -RRB- 50458 372 4 [ [ -LRB- 50458 372 5 42 42 CD 50458 372 6 ] ] -RRB- 50458 372 7 It -PRON- PRP 50458 372 8 is be VBZ 50458 372 9 necessary necessary JJ 50458 372 10 here here RB 50458 372 11 to to TO 50458 372 12 consult consult VB 50458 372 13 the the DT 50458 372 14 work work NN 50458 372 15 by by IN 50458 372 16 LEVADITI levaditi NN 50458 372 17 : : : 50458 372 18 Le Le NNP 50458 372 19 Leucocyte Leucocyte NNP 50458 372 20 et et NNP 50458 372 21 ses se VBZ 50458 372 22 Granulations Granulations NNPS 50458 372 23 . . . 50458 373 1 _ _ NNP 50458 373 2 Scientia Scientia NNP 50458 373 3 _ _ NNP 50458 373 4 , , , 50458 373 5 Naud Naud NNP 50458 373 6 , , , 50458 373 7 publisher publisher NN 50458 373 8 , , , 50458 373 9 Paris Paris NNP 50458 373 10 , , , 50458 373 11 1903 1903 CD 50458 373 12 ; ; : 50458 373 13 also also RB 50458 373 14 METCHNIKOFF metchnikoff JJ 50458 373 15 : : : 50458 373 16 L'Immunité L'Immunité NNP 50458 373 17 , , , 50458 373 18 Paris Paris NNP 50458 373 19 , , , 50458 373 20 1902 1902 CD 50458 373 21 , , , 50458 373 22 Masson Masson NNP 50458 373 23 , , , 50458 373 24 publisher publisher NN 50458 373 25 . . . 50458 374 1 Metchnikoff Metchnikoff NNP 50458 374 2 has have VBZ 50458 374 3 shown show VBN 50458 374 4 that that IN 50458 374 5 the the DT 50458 374 6 moment moment NN 50458 374 7 a a DT 50458 374 8 foreign foreign JJ 50458 374 9 element element NN 50458 374 10 , , , 50458 374 11 particularly particularly RB 50458 374 12 a a DT 50458 374 13 microbe microbe NN 50458 374 14 , , , 50458 374 15 enters enter VBZ 50458 374 16 the the DT 50458 374 17 organism organism NN 50458 374 18 , , , 50458 374 19 these these DT 50458 374 20 leucocytes leucocyte NNS 50458 374 21 come come VBP 50458 374 22 flocking flock VBG 50458 374 23 from from IN 50458 374 24 all all DT 50458 374 25 parts part NNS 50458 374 26 of of IN 50458 374 27 the the DT 50458 374 28 body body NN 50458 374 29 , , , 50458 374 30 collect collect VB 50458 374 31 around around IN 50458 374 32 the the DT 50458 374 33 bacterial bacterial JJ 50458 374 34 element element NN 50458 374 35 , , , 50458 374 36 penetrate penetrate VB 50458 374 37 it -PRON- PRP 50458 374 38 , , , 50458 374 39 and and CC 50458 374 40 begin begin VB 50458 374 41 to to TO 50458 374 42 digest digest VB 50458 374 43 it -PRON- PRP 50458 374 44 . . . 50458 375 1 These these DT 50458 375 2 elements element NNS 50458 375 3 have have VBP 50458 375 4 received receive VBN 50458 375 5 the the DT 50458 375 6 name name NN 50458 375 7 _ _ NNP 50458 375 8 phagocytes phagocyte NNS 50458 375 9 _ _ NNP 50458 375 10 . . . 50458 376 1 The the DT 50458 376 2 name name NN 50458 376 3 _ _ NNP 50458 376 4 chemotaxis chemotaxis NNP 50458 376 5 _ _ NNP 50458 376 6 has have VBZ 50458 376 7 been be VBN 50458 376 8 given give VBN 50458 376 9 to to IN 50458 376 10 the the DT 50458 376 11 property property NN 50458 376 12 by by IN 50458 376 13 virtue virtue NN 50458 376 14 of of IN 50458 376 15 which which WDT 50458 376 16 they -PRON- PRP 50458 376 17 approach approach VBP 50458 376 18 ( ( -LRB- 50458 376 19 positive positive JJ 50458 376 20 chemotaxis chemotaxi NNS 50458 376 21 ) ) -RRB- 50458 376 22 or or CC 50458 376 23 move move VB 50458 376 24 away away RB 50458 376 25 from from IN 50458 376 26 ( ( -LRB- 50458 376 27 negative negative JJ 50458 376 28 chemotaxis chemotaxis NN 50458 376 29 ) ) -RRB- 50458 376 30 certain certain JJ 50458 376 31 substances substance NNS 50458 376 32 which which WDT 50458 376 33 affect affect VBP 50458 376 34 them -PRON- PRP 50458 376 35 powerfully powerfully RB 50458 376 36 . . . 50458 377 1 Experiments experiment NNS 50458 377 2 have have VBP 50458 377 3 shown show VBN 50458 377 4 that that IN 50458 377 5 the the DT 50458 377 6 leucocytes leucocyte NNS 50458 377 7 are be VBP 50458 377 8 attracted attract VBN 50458 377 9 by by IN 50458 377 10 the the DT 50458 377 11 products product NNS 50458 377 12 secreted secrete VBN 50458 377 13 by by IN 50458 377 14 pathogenic pathogenic JJ 50458 377 15 microbes microbe NNS 50458 377 16 , , , 50458 377 17 or or CC 50458 377 18 saprophytes saprophyte NNS 50458 377 19 . . . 50458 378 1 Attracted attract VBN 50458 378 2 by by IN 50458 378 3 the the DT 50458 378 4 latter latter JJ 50458 378 5 , , , 50458 378 6 the the DT 50458 378 7 white white JJ 50458 378 8 corpuscles corpuscle NNS 50458 378 9 surround surround VBP 50458 378 10 , , , 50458 378 11 envelop envelop NN 50458 378 12 , , , 50458 378 13 and and CC 50458 378 14 finally finally RB 50458 378 15 digest digest VB 50458 378 16 them -PRON- PRP 50458 378 17 ; ; : 50458 378 18 and and CC 50458 378 19 when when WRB 50458 378 20 it -PRON- PRP 50458 378 21 happens happen VBZ 50458 378 22 that that IN 50458 378 23 all all PDT 50458 378 24 the the DT 50458 378 25 pathogenic pathogenic JJ 50458 378 26 microbes microbe NNS 50458 378 27 within within IN 50458 378 28 an an DT 50458 378 29 organism organism NN 50458 378 30 are be VBP 50458 378 31 absorbed absorb VBN 50458 378 32 , , , 50458 378 33 the the DT 50458 378 34 organism organism NN 50458 378 35 survives survive VBZ 50458 378 36 , , , 50458 378 37 while while IN 50458 378 38 in in IN 50458 378 39 the the DT 50458 378 40 contrary contrary JJ 50458 378 41 case case NN 50458 378 42 it -PRON- PRP 50458 378 43 succumbs succumb VBZ 50458 378 44 . . . 50458 379 1 Attention attention NN 50458 379 2 must must MD 50458 379 3 be be VB 50458 379 4 called call VBN 50458 379 5 to to IN 50458 379 6 this this DT 50458 379 7 attack attack NN 50458 379 8 by by IN 50458 379 9 the the DT 50458 379 10 white white JJ 50458 379 11 corpuscles corpuscle NNS 50458 379 12 within within IN 50458 379 13 the the DT 50458 379 14 limits limit NNS 50458 379 15 where where WRB 50458 379 16 they -PRON- PRP 50458 379 17 are be VBP 50458 379 18 normally normally RB 50458 379 19 confined confine VBN 50458 379 20 . . . 50458 380 1 It -PRON- PRP 50458 380 2 is be VBZ 50458 380 3 a a DT 50458 380 4 pathologic pathologic JJ 50458 380 5 diapedesis diapedesis NN 50458 380 6 -- -- : 50458 380 7 a a DT 50458 380 8 leucocytosis leucocytosis NN 50458 380 9 provoked provoke VBN 50458 380 10 by by IN 50458 380 11 the the DT 50458 380 12 irritation irritation NN 50458 380 13 of of IN 50458 380 14 the the DT 50458 380 15 tissues tissue NNS 50458 380 16 -- -- : 50458 380 17 and and CC 50458 380 18 caused cause VBN 50458 380 19 either either CC 50458 380 20 by by IN 50458 380 21 the the DT 50458 380 22 presence presence NN 50458 380 23 alone alone RB 50458 380 24 of of IN 50458 380 25 foreign foreign JJ 50458 380 26 elements element NNS 50458 380 27 , , , 50458 380 28 or or CC 50458 380 29 by by IN 50458 380 30 the the DT 50458 380 31 soluble soluble JJ 50458 380 32 products product NNS 50458 380 33 secreted secrete VBN 50458 380 34 by by IN 50458 380 35 them -PRON- PRP 50458 380 36 . . . 50458 381 1 When when WRB 50458 381 2 , , , 50458 381 3 for for IN 50458 381 4 any any DT 50458 381 5 reason reason NN 50458 381 6 whatever whatever WDT 50458 381 7 , , , 50458 381 8 this this DT 50458 381 9 phagocytic phagocytic JJ 50458 381 10 action action NN 50458 381 11 is be VBZ 50458 381 12 impeded impede VBN 50458 381 13 , , , 50458 381 14 the the DT 50458 381 15 resistance resistance NN 50458 381 16 of of IN 50458 381 17 the the DT 50458 381 18 organism organism NN 50458 381 19 to to IN 50458 381 20 pathogenic pathogenic JJ 50458 381 21 infection infection NN 50458 381 22 ceases cease VBZ 50458 381 23 to to TO 50458 381 24 be be VB 50458 381 25 effective effective JJ 50458 381 26 , , , 50458 381 27 and and CC 50458 381 28 the the DT 50458 381 29 organism organism NN 50458 381 30 may may MD 50458 381 31 therefore therefore RB 50458 381 32 be be VB 50458 381 33 invaded invade VBN 50458 381 34 by by IN 50458 381 35 the the DT 50458 381 36 microbe microbe NN 50458 381 37 . . . 50458 382 1 Numerous numerous JJ 50458 382 2 causes cause NNS 50458 382 3 may may MD 50458 382 4 contribute contribute VB 50458 382 5 to to TO 50458 382 6 impede impede VB 50458 382 7 this this DT 50458 382 8 action action NN 50458 382 9 . . . 50458 383 1 = = NFP 50458 383 2 The the DT 50458 383 3 Antitoxins.= antitoxins.= NN 50458 383 4 We -PRON- PRP 50458 383 5 have have VBP 50458 383 6 seen see VBN 50458 383 7 that that IN 50458 383 8 the the DT 50458 383 9 second second JJ 50458 383 10 means mean NNS 50458 383 11 of of IN 50458 383 12 defense defense NN 50458 383 13 possessed possess VBN 50458 383 14 by by IN 50458 383 15 the the DT 50458 383 16 organism organism NN 50458 383 17 resides reside VBZ 50458 383 18 in in IN 50458 383 19 the the DT 50458 383 20 action action NN 50458 383 21 of of IN 50458 383 22 special special JJ 50458 383 23 products product NNS 50458 383 24 , , , 50458 383 25 true true JJ 50458 383 26 defensive defensive JJ 50458 383 27 secretions secretion NNS 50458 383 28 , , , 50458 383 29 possessing possess VBG 50458 383 30 an an DT 50458 383 31 activity activity NN 50458 383 32 contrary contrary JJ 50458 383 33 to to IN 50458 383 34 that that DT 50458 383 35 of of IN 50458 383 36 the the DT 50458 383 37 toxins toxin NNS 50458 383 38 , , , 50458 383 39 and and CC 50458 383 40 which which WDT 50458 383 41 are be VBP 50458 383 42 secreted secrete VBN 50458 383 43 by by IN 50458 383 44 the the DT 50458 383 45 cells cell NNS 50458 383 46 of of IN 50458 383 47 the the DT 50458 383 48 organism organism NN 50458 383 49 under under IN 50458 383 50 the the DT 50458 383 51 influence influence NN 50458 383 52 of of IN 50458 383 53 the the DT 50458 383 54 vaccins vaccin NNS 50458 383 55 . . . 50458 384 1 This this DT 50458 384 2 is be VBZ 50458 384 3 a a DT 50458 384 4 property property NN 50458 384 5 common common JJ 50458 384 6 to to IN 50458 384 7 every every DT 50458 384 8 organism organism NN 50458 384 9 , , , 50458 384 10 and and CC 50458 384 11 which which WDT 50458 384 12 is be VBZ 50458 384 13 observed observe VBN 50458 384 14 even even RB 50458 384 15 in in IN 50458 384 16 non non JJ 50458 384 17 - - JJ 50458 384 18 vaccinated vaccinated JJ 50458 384 19 subjects subject NNS 50458 384 20 , , , 50458 384 21 although although IN 50458 384 22 in in IN 50458 384 23 this this DT 50458 384 24 case case NN 50458 384 25 the the DT 50458 384 26 secretion secretion NN 50458 384 27 forms form VBZ 50458 384 28 with with IN 50458 384 29 great great JJ 50458 384 30 difficulty difficulty NN 50458 384 31 and and CC 50458 384 32 in in IN 50458 384 33 small small JJ 50458 384 34 quantity quantity NN 50458 384 35 . . . 50458 385 1 When when WRB 50458 385 2 an an DT 50458 385 3 organism organism NN 50458 385 4 subjected subject VBD 50458 385 5 to to IN 50458 385 6 the the DT 50458 385 7 toxic toxic JJ 50458 385 8 action action NN 50458 385 9 of of IN 50458 385 10 a a DT 50458 385 11 bacterial bacterial JJ 50458 385 12 infection infection NN 50458 385 13 does do VBZ 50458 385 14 not not RB 50458 385 15 succumb succumb VB 50458 385 16 to to IN 50458 385 17 the the DT 50458 385 18 intoxication intoxication NN 50458 385 19 , , , 50458 385 20 it -PRON- PRP 50458 385 21 emerges emerge VBZ 50458 385 22 from from IN 50458 385 23 the the DT 50458 385 24 test test NN 50458 385 25 gifted gift VBN 50458 385 26 with with IN 50458 385 27 a a DT 50458 385 28 new new JJ 50458 385 29 property property NN 50458 385 30 , , , 50458 385 31 which which WDT 50458 385 32 may may MD 50458 385 33 be be VB 50458 385 34 augmented augment VBN 50458 385 35 by by IN 50458 385 36 habituation habituation NN 50458 385 37 , , , 50458 385 38 and and CC 50458 385 39 which which WDT 50458 385 40 borders border VBZ 50458 385 41 on on IN 50458 385 42 immunity immunity NN 50458 385 43 . . . 50458 386 1 At at IN 50458 386 2 first first RB 50458 386 3 we -PRON- PRP 50458 386 4 were be VBD 50458 386 5 content content JJ 50458 386 6 to to TO 50458 386 7 vaccinate vaccinate VB 50458 386 8 small small JJ 50458 386 9 animals animal NNS 50458 386 10 in in IN 50458 386 11 the the DT 50458 386 12 laboratory laboratory NN 50458 386 13 , , , 50458 386 14 but but CC 50458 386 15 in in IN 50458 386 16 proportion proportion NN 50458 386 17 as as IN 50458 386 18 the the DT 50458 386 19 discoveries discovery NNS 50458 386 20 in in IN 50458 386 21 this this DT 50458 386 22 domain domain NN 50458 386 23 extended extend VBD 50458 386 24 , , , 50458 386 25 and and CC 50458 386 26 there there RB 50458 386 27 developed develop VBD 50458 386 28 a a DT 50458 386 29 need need NN 50458 386 30 for for IN 50458 386 31 large large JJ 50458 386 32 quantities quantity NNS 50458 386 33 of of IN 50458 386 34 antitoxins antitoxin NNS 50458 386 35 , , , 50458 386 36 recourse recourse NNP 50458 386 37 was be VBD 50458 386 38 had have VBN 50458 386 39 to to IN 50458 386 40 the the DT 50458 386 41 larger large JJR 50458 386 42 animals animal NNS 50458 386 43 , , , 50458 386 44 particularly particularly RB 50458 386 45 horses horse NNS 50458 386 46 and and CC 50458 386 47 cattle cattle NNS 50458 386 48 . . . 50458 387 1 From from IN 50458 387 2 the the DT 50458 387 3 moment moment NN 50458 387 4 that that IN 50458 387 5 large large JJ 50458 387 6 quantities quantity NNS 50458 387 7 of of IN 50458 387 8 blood blood NN 50458 387 9 and and CC 50458 387 10 antitoxic antitoxic NN 50458 387 11 serum serum NNP 50458 387 12 were be VBD 50458 387 13 at at IN 50458 387 14 command command NN 50458 387 15 , , , 50458 387 16 search search NN 50458 387 17 was be VBD 50458 387 18 made make VBN 50458 387 19 for for IN 50458 387 20 a a DT 50458 387 21 means means NN 50458 387 22 of of IN 50458 387 23 isolating isolate VBG 50458 387 24 the the DT 50458 387 25 antitoxin antitoxin NN 50458 387 26 and and CC 50458 387 27 determining determine VBG 50458 387 28 its -PRON- PRP$ 50458 387 29 properties property NNS 50458 387 30 . . . 50458 388 1 Experiments experiment NNS 50458 388 2 so so RB 50458 388 3 far far RB 50458 388 4 made make VBN 50458 388 5 have have VBP 50458 388 6 shown show VBN 50458 388 7 that that IN 50458 388 8 the the DT 50458 388 9 antitoxins antitoxin NNS 50458 388 10 are be VBP 50458 388 11 substances substance NNS 50458 388 12 of of IN 50458 388 13 an an DT 50458 388 14 albuminoid albuminoid NN 50458 388 15 nature nature NN 50458 388 16 , , , 50458 388 17 of of IN 50458 388 18 unknown unknown JJ 50458 388 19 composition composition NN 50458 388 20 , , , 50458 388 21 and and CC 50458 388 22 which which WDT 50458 388 23 are be VBP 50458 388 24 very very RB 50458 388 25 closely closely RB 50458 388 26 united united JJ 50458 388 27 to to IN 50458 388 28 the the DT 50458 388 29 albuminoid albuminoid JJ 50458 388 30 substances substance NNS 50458 388 31 of of IN 50458 388 32 the the DT 50458 388 33 serum serum NN 50458 388 34 . . . 50458 389 1 It -PRON- PRP 50458 389 2 must must MD 50458 389 3 be be VB 50458 389 4 observed observe VBN 50458 389 5 , , , 50458 389 6 however however RB 50458 389 7 , , , 50458 389 8 that that IN 50458 389 9 Behring Behring NNP 50458 389 10 and and CC 50458 389 11 Knorr Knorr NNP 50458 389 12 oppose oppose VBP 50458 389 13 the the DT 50458 389 14 assertion assertion NN 50458 389 15 regarding regard VBG 50458 389 16 the the DT 50458 389 17 albuminoid albuminoid NN 50458 389 18 nature nature NN 50458 389 19 of of IN 50458 389 20 tetanic tetanic JJ 50458 389 21 antitoxin antitoxin NN 50458 389 22 , , , 50458 389 23 but but CC 50458 389 24 their -PRON- PRP$ 50458 389 25 reasons reason NNS 50458 389 26 for for IN 50458 389 27 this this DT 50458 389 28 do do VBP 50458 389 29 not not RB 50458 389 30 appear appear VB 50458 389 31 to to TO 50458 389 32 be be VB 50458 389 33 well well RB 50458 389 34 founded found VBN 50458 389 35 . . . 50458 390 1 In in IN 50458 390 2 general general JJ 50458 390 3 , , , 50458 390 4 these these DT 50458 390 5 antitoxins antitoxin NNS 50458 390 6 are be VBP 50458 390 7 precipitable precipitable JJ 50458 390 8 with with IN 50458 390 9 the the DT 50458 390 10 globulins globulin NNS 50458 390 11 , , , 50458 390 12 and and CC 50458 390 13 possess possess VBP 50458 390 14 quite quite RB 50458 390 15 considerable considerable JJ 50458 390 16 powers power NNS 50458 390 17 of of IN 50458 390 18 resistance resistance NN 50458 390 19 towards towards IN 50458 390 20 physical physical JJ 50458 390 21 and and CC 50458 390 22 chemical chemical JJ 50458 390 23 agents agent NNS 50458 390 24 . . . 50458 391 1 Thus thus RB 50458 391 2 they -PRON- PRP 50458 391 3 are be VBP 50458 391 4 destroyed destroy VBN 50458 391 5 only only RB 50458 391 6 at at IN 50458 391 7 a a DT 50458 391 8 temperature temperature NN 50458 391 9 above above IN 50458 391 10 60 60 CD 50458 391 11 - - SYM 50458 391 12 65 65 CD 50458 391 13 ° ° , 50458 391 14 C. C. NNP 50458 391 15 Kept Kept NNP 50458 391 16 in in IN 50458 391 17 the the DT 50458 391 18 dry dry JJ 50458 391 19 state state NN 50458 391 20 , , , 50458 391 21 in in IN 50458 391 22 the the DT 50458 391 23 residue residue NN 50458 391 24 of of IN 50458 391 25 evaporated evaporated JJ 50458 391 26 serum serum NN 50458 391 27 , , , 50458 391 28 and and CC 50458 391 29 away away RB 50458 391 30 from from IN 50458 391 31 the the DT 50458 391 32 light light NN 50458 391 33 and and CC 50458 391 34 all all DT 50458 391 35 oxidizing oxidizing JJ 50458 391 36 action action NN 50458 391 37 , , , 50458 391 38 it -PRON- PRP 50458 391 39 is be VBZ 50458 391 40 possible possible JJ 50458 391 41 to to TO 50458 391 42 preserve preserve VB 50458 391 43 their -PRON- PRP$ 50458 391 44 activity activity NN 50458 391 45 for for IN 50458 391 46 a a DT 50458 391 47 very very RB 50458 391 48 long long JJ 50458 391 49 time time NN 50458 391 50 . . . 50458 392 1 They -PRON- PRP 50458 392 2 are be VBP 50458 392 3 essentially essentially RB 50458 392 4 humoral humoral JJ 50458 392 5 substances substance NNS 50458 392 6 ; ; : 50458 392 7 they -PRON- PRP 50458 392 8 are be VBP 50458 392 9 found find VBN 50458 392 10 in in IN 50458 392 11 the the DT 50458 392 12 blood blood NN 50458 392 13 of of IN 50458 392 14 vaccinated vaccinated JJ 50458 392 15 animals animal NNS 50458 392 16 , , , 50458 392 17 from from IN 50458 392 18 which which WDT 50458 392 19 may may MD 50458 392 20 be be VB 50458 392 21 obtained obtain VBN 50458 392 22 antitoxic antitoxic NN 50458 392 23 serums serum NNS 50458 392 24 with with IN 50458 392 25 a a DT 50458 392 26 specific specific JJ 50458 392 27 but but CC 50458 392 28 transient transient JJ 50458 392 29 immunity immunity NN 50458 392 30 ; ; : 50458 392 31 and and CC 50458 392 32 they -PRON- PRP 50458 392 33 are be VBP 50458 392 34 also also RB 50458 392 35 found find VBN 50458 392 36 in in IN 50458 392 37 the the DT 50458 392 38 plasmas plasma NNS 50458 392 39 of of IN 50458 392 40 the the DT 50458 392 41 lymph lymph NN 50458 392 42 and and CC 50458 392 43 exudates exudate NNS 50458 392 44 , , , 50458 392 45 in in IN 50458 392 46 aqueous aqueous JJ 50458 392 47 tumors tumor NNS 50458 392 48 , , , 50458 392 49 and and CC 50458 392 50 in in IN 50458 392 51 the the DT 50458 392 52 milk milk NN 50458 392 53 . . . 50458 393 1 They -PRON- PRP 50458 393 2 are be VBP 50458 393 3 seldom seldom RB 50458 393 4 found find VBN 50458 393 5 in in IN 50458 393 6 the the DT 50458 393 7 cells cell NNS 50458 393 8 . . . 50458 394 1 = = NFP 50458 394 2 Mode mode NN 50458 394 3 of of IN 50458 394 4 Action.=--Frequent action.=--frequent JJ 50458 394 5 attention attention NN 50458 394 6 has have VBZ 50458 394 7 been be VBN 50458 394 8 paid pay VBN 50458 394 9 to to IN 50458 394 10 the the DT 50458 394 11 mode mode NN 50458 394 12 of of IN 50458 394 13 action action NN 50458 394 14 of of IN 50458 394 15 the the DT 50458 394 16 antitoxins antitoxin NNS 50458 394 17 upon upon IN 50458 394 18 the the DT 50458 394 19 toxins toxin NNS 50458 394 20 , , , 50458 394 21 a a DT 50458 394 22 phenomenon phenomenon NN 50458 394 23 of of IN 50458 394 24 great great JJ 50458 394 25 importance importance NN 50458 394 26 in in IN 50458 394 27 relation relation NN 50458 394 28 to to IN 50458 394 29 the the DT 50458 394 30 phenomenon phenomenon NN 50458 394 31 of of IN 50458 394 32 immunity immunity NN 50458 394 33 acquired acquire VBN 50458 394 34 against against IN 50458 394 35 the the DT 50458 394 36 toxins toxin NNS 50458 394 37 . . . 50458 395 1 At at IN 50458 395 2 the the DT 50458 395 3 beginning beginning NN 50458 395 4 of of IN 50458 395 5 our -PRON- PRP$ 50458 395 6 knowledge knowledge NN 50458 395 7 on on IN 50458 395 8 this this DT 50458 395 9 subject subject NN 50458 395 10 , , , 50458 395 11 the the DT 50458 395 12 idea idea NN 50458 395 13 of of IN 50458 395 14 a a DT 50458 395 15 destruction destruction NN 50458 395 16 of of IN 50458 395 17 the the DT 50458 395 18 toxin toxin NN 50458 395 19 immediately immediately RB 50458 395 20 suggested suggest VBD 50458 395 21 itself -PRON- PRP 50458 395 22 , , , 50458 395 23 and and CC 50458 395 24 was be VBD 50458 395 25 advanced advance VBN 50458 395 26 by by IN 50458 395 27 von von NNP 50458 395 28 Behring Behring NNP 50458 395 29 . . . 50458 396 1 [ [ -LRB- 50458 396 2 43 43 CD 50458 396 3 ] ] -RRB- 50458 396 4 According accord VBG 50458 396 5 to to IN 50458 396 6 this this DT 50458 396 7 scientist scientist NN 50458 396 8 the the DT 50458 396 9 antibody antibody NN 50458 396 10 inhibits inhibit VBZ 50458 396 11 the the DT 50458 396 12 morbigenic morbigenic JJ 50458 396 13 action action NN 50458 396 14 of of IN 50458 396 15 the the DT 50458 396 16 toxin toxin NN 50458 396 17 by by IN 50458 396 18 neutralizing neutralize VBG 50458 396 19 the the DT 50458 396 20 toxin toxin NN 50458 396 21 , , , 50458 396 22 combining combine VBG 50458 396 23 with with IN 50458 396 24 the the DT 50458 396 25 latter latter JJ 50458 396 26 to to TO 50458 396 27 form form VB 50458 396 28 a a DT 50458 396 29 compound compound NN 50458 396 30 of of IN 50458 396 31 a a DT 50458 396 32 chemical chemical NN 50458 396 33 nature nature NN 50458 396 34 which which WDT 50458 396 35 is be VBZ 50458 396 36 devoid devoid JJ 50458 396 37 of of IN 50458 396 38 toxicity toxicity NN 50458 396 39 and and CC 50458 396 40 without without IN 50458 396 41 action action NN 50458 396 42 on on IN 50458 396 43 the the DT 50458 396 44 organism organism NN 50458 396 45 . . . 50458 397 1 According accord VBG 50458 397 2 to to IN 50458 397 3 this this DT 50458 397 4 theory theory NN 50458 397 5 , , , 50458 397 6 the the DT 50458 397 7 influence influence NN 50458 397 8 of of IN 50458 397 9 the the DT 50458 397 10 antitoxin antitoxin NN 50458 397 11 on on IN 50458 397 12 the the DT 50458 397 13 toxin toxin NN 50458 397 14 is be VBZ 50458 397 15 direct direct JJ 50458 397 16 , , , 50458 397 17 and and CC 50458 397 18 does do VBZ 50458 397 19 not not RB 50458 397 20 require require VB 50458 397 21 the the DT 50458 397 22 intervention intervention NN 50458 397 23 of of IN 50458 397 24 the the DT 50458 397 25 living live VBG 50458 397 26 cellular cellular JJ 50458 397 27 protoplasm protoplasm NN 50458 397 28 . . . 50458 398 1 Such such JJ 50458 398 2 was be VBD 50458 398 3 also also RB 50458 398 4 the the DT 50458 398 5 belief belief NN 50458 398 6 of of IN 50458 398 7 Prof. Prof. NNP 50458 399 1 Ehrlich ehrlich NN 50458 399 2 . . . 50458 400 1 [ [ -LRB- 50458 400 2 44 44 CD 50458 400 3 ] ] -RRB- 50458 400 4 [ [ -LRB- 50458 400 5 43 43 CD 50458 400 6 ] ] -RRB- 50458 400 7 VON VON NNP 50458 400 8 BEHRING BEHRING NNP 50458 400 9 and and CC 50458 400 10 KITASATO KITASATO NNP 50458 400 11 : : : 50458 400 12 _ _ NNP 50458 400 13 Deutsch Deutsch NNP 50458 400 14 . . . 50458 401 1 med med JJ 50458 401 2 . . . 50458 402 1 Wochenschr Wochenschr NNP 50458 402 2 . . . 50458 402 3 _ _ NNP 50458 402 4 , , , 50458 402 5 1890 1890 CD 50458 402 6 , , , 50458 402 7 p. p. NN 50458 402 8 1113 1113 CD 50458 402 9 . . . 50458 403 1 [ [ -LRB- 50458 403 2 44 44 CD 50458 403 3 ] ] -RRB- 50458 403 4 EHRLICH ehrlich NN 50458 403 5 : : : 50458 403 6 _ _ NNP 50458 403 7 Klin Klin NNP 50458 403 8 . . . 50458 404 1 Jahrb Jahrb NNP 50458 404 2 . . . 50458 404 3 _ _ NNP 50458 404 4 1897 1897 CD 50458 404 5 , , , 50458 404 6 VI VI NNP 50458 404 7 , , , 50458 404 8 p. p. NN 50458 404 9 292 292 CD 50458 404 10 . . . 50458 405 1 Buchner buchner NN 50458 405 2 , , , 50458 405 3 a a DT 50458 405 4 little little JJ 50458 405 5 later later RB 50458 405 6 , , , 50458 405 7 believed believe VBD 50458 405 8 that that IN 50458 405 9 the the DT 50458 405 10 antitoxin antitoxin NN 50458 405 11 , , , 50458 405 12 instead instead RB 50458 405 13 of of IN 50458 405 14 acting act VBG 50458 405 15 directly directly RB 50458 405 16 on on IN 50458 405 17 the the DT 50458 405 18 toxin toxin NN 50458 405 19 , , , 50458 405 20 exercised exercise VBD 50458 405 21 a a DT 50458 405 22 direct direct JJ 50458 405 23 influence influence NN 50458 405 24 on on IN 50458 405 25 the the DT 50458 405 26 living live VBG 50458 405 27 elements element NNS 50458 405 28 of of IN 50458 405 29 the the DT 50458 405 30 organism organism NN 50458 405 31 , , , 50458 405 32 preserving preserve VBG 50458 405 33 them -PRON- PRP 50458 405 34 from from IN 50458 405 35 intoxication intoxication NN 50458 405 36 . . . 50458 406 1 [ [ -LRB- 50458 406 2 45 45 CD 50458 406 3 ] ] -RRB- 50458 406 4 [ [ -LRB- 50458 406 5 45 45 CD 50458 406 6 ] ] -RRB- 50458 406 7 BUCHNER buchner NN 50458 406 8 : : : 50458 406 9 _ _ NNP 50458 406 10 Münchener Münchener NNP 50458 406 11 med med NNP 50458 406 12 . . . 50458 407 1 Wochenschr Wochenschr NNP 50458 407 2 . . . 50458 407 3 _ _ NNP 50458 407 4 , , , 50458 407 5 1893 1893 CD 50458 407 6 , , , 50458 407 7 p. p. NN 50458 407 8 480 480 CD 50458 407 9 . . . 50458 408 1 Such such JJ 50458 408 2 was be VBD 50458 408 3 also also RB 50458 408 4 the the DT 50458 408 5 opinion opinion NN 50458 408 6 of of IN 50458 408 7 Roux[46 Roux[46 NNP 50458 408 8 ] ] -RRB- 50458 408 9 ; ; : 50458 408 10 and and CC 50458 408 11 Calmette Calmette NNP 50458 408 12 demonstrated demonstrate VBD 50458 408 13 that that IN 50458 408 14 a a DT 50458 408 15 mixture mixture NN 50458 408 16 of of IN 50458 408 17 venom venom NN 50458 408 18 and and CC 50458 408 19 of of IN 50458 408 20 a a DT 50458 408 21 non non JJ 50458 408 22 - - JJ 50458 408 23 toxic toxic JJ 50458 408 24 antivenom antivenom NN 50458 408 25 recovered recover VBD 50458 408 26 its -PRON- PRP$ 50458 408 27 toxicity toxicity NN 50458 408 28 on on IN 50458 408 29 being be VBG 50458 408 30 heated heat VBN 50458 408 31 to to IN 50458 408 32 68 68 CD 50458 408 33 ° ° , 50458 408 34 C C NNP 50458 408 35 , , , 50458 408 36 whereby whereby WRB 50458 408 37 the the DT 50458 408 38 antivenom antivenom NN 50458 408 39 was be VBD 50458 408 40 destroyed destroy VBN 50458 408 41 ( ( -LRB- 50458 408 42 Calmette calmette NN 50458 408 43 : : : 50458 408 44 _ _ NNP 50458 408 45 Le Le NNP 50458 408 46 Venin Venin NNP 50458 408 47 des des NNP 50458 408 48 Serpents Serpents NNP 50458 408 49 _ _ NNP 50458 408 50 , , , 50458 408 51 Paris Paris NNP 50458 408 52 , , , 50458 408 53 1897 1897 CD 50458 408 54 , , , 50458 408 55 p. p. NN 50458 408 56 58 58 CD 50458 408 57 ) ) -RRB- 50458 408 58 ; ; : 50458 408 59 and and CC 50458 408 60 Wassermann Wassermann NNP 50458 408 61 arrived arrive VBD 50458 408 62 at at IN 50458 408 63 the the DT 50458 408 64 same same JJ 50458 408 65 result result NN 50458 408 66 . . . 50458 409 1 [ [ -LRB- 50458 409 2 47 47 CD 50458 409 3 ] ] -RRB- 50458 409 4 [ [ -LRB- 50458 409 5 46 46 CD 50458 409 6 ] ] -RRB- 50458 409 7 ROUX roux NN 50458 409 8 : : : 50458 409 9 _ _ NNP 50458 409 10 Annales Annales NNP 50458 409 11 de de NNP 50458 409 12 l'Institut l'Institut NNP 50458 409 13 Pasteur Pasteur NNP 50458 409 14 _ _ NNP 50458 409 15 , , , 50458 409 16 1894 1894 CD 50458 409 17 , , , 50458 409 18 VIII VIII NNP 50458 409 19 , , , 50458 409 20 p. p. NN 50458 409 21 724 724 CD 50458 409 22 . . . 50458 410 1 [ [ -LRB- 50458 410 2 47 47 CD 50458 410 3 ] ] -RRB- 50458 410 4 WASSERMANN wassermann NN 50458 410 5 : : : 50458 410 6 _ _ NNP 50458 410 7 Zeitschr Zeitschr NNP 50458 410 8 . . . 50458 411 1 für für NNP 50458 411 2 Hygiene Hygiene NNP 50458 411 3 _ _ NNP 50458 411 4 . . . 50458 412 1 The the DT 50458 412 2 array array NN 50458 412 3 of of IN 50458 412 4 proofs proof NNS 50458 412 5 offered offer VBN 50458 412 6 by by IN 50458 412 7 these these DT 50458 412 8 scientists scientist NNS 50458 412 9 , , , 50458 412 10 which which WDT 50458 412 11 we -PRON- PRP 50458 412 12 can can MD 50458 412 13 not not RB 50458 412 14 here here RB 50458 412 15 enlarge enlarge VB 50458 412 16 upon upon IN 50458 412 17 without without IN 50458 412 18 uselessly uselessly RB 50458 412 19 extending extend VBG 50458 412 20 our -PRON- PRP$ 50458 412 21 subject subject NN 50458 412 22 , , , 50458 412 23 would would MD 50458 412 24 tend tend VB 50458 412 25 to to TO 50458 412 26 make make VB 50458 412 27 one one CD 50458 412 28 believe believe VB 50458 412 29 , , , 50458 412 30 at at IN 50458 412 31 first first JJ 50458 412 32 glance glance NN 50458 412 33 , , , 50458 412 34 that that IN 50458 412 35 the the DT 50458 412 36 antitoxin antitoxin NN 50458 412 37 does do VBZ 50458 412 38 not not RB 50458 412 39 act act VB 50458 412 40 directly directly RB 50458 412 41 on on IN 50458 412 42 the the DT 50458 412 43 toxin toxin NN 50458 412 44 , , , 50458 412 45 but but CC 50458 412 46 at at IN 50458 412 47 the the DT 50458 412 48 present present JJ 50458 412 49 time time NN 50458 412 50 Buchner Buchner NNP 50458 412 51 's 's POS 50458 412 52 theory theory NN 50458 412 53 appears appear VBZ 50458 412 54 untenable untenable JJ 50458 412 55 . . . 50458 413 1 Numerous numerous JJ 50458 413 2 researches research NNS 50458 413 3 have have VBP 50458 413 4 proved prove VBN 50458 413 5 conclusively conclusively RB 50458 413 6 that that IN 50458 413 7 the the DT 50458 413 8 toxin toxin NN 50458 413 9 and and CC 50458 413 10 the the DT 50458 413 11 antitoxin antitoxin NN 50458 413 12 have have VBP 50458 413 13 a a DT 50458 413 14 specific specific JJ 50458 413 15 affinity affinity NN 50458 413 16 for for IN 50458 413 17 each each DT 50458 413 18 other other JJ 50458 413 19 , , , 50458 413 20 by by IN 50458 413 21 virtue virtue NN 50458 413 22 of of IN 50458 413 23 which which WDT 50458 413 24 these these DT 50458 413 25 principles principle NNS 50458 413 26 combine combine VBP 50458 413 27 to to TO 50458 413 28 form form VB 50458 413 29 a a DT 50458 413 30 substance substance NN 50458 413 31 free free JJ 50458 413 32 from from IN 50458 413 33 all all DT 50458 413 34 toxicity toxicity NN 50458 413 35 , , , 50458 413 36 but but CC 50458 413 37 unstable unstable JJ 50458 413 38 , , , 50458 413 39 and and CC 50458 413 40 which which WDT 50458 413 41 may may MD 50458 413 42 be be VB 50458 413 43 decomposed decompose VBN 50458 413 44 by by IN 50458 413 45 heat heat NN 50458 413 46 or or CC 50458 413 47 certain certain JJ 50458 413 48 other other JJ 50458 413 49 factors factor NNS 50458 413 50 . . . 50458 414 1 [ [ -LRB- 50458 414 2 48 48 CD 50458 414 3 ] ] -RRB- 50458 414 4 [ [ -LRB- 50458 414 5 48 48 CD 50458 414 6 ] ] -RRB- 50458 414 7 J. J. NNP 50458 414 8 DANZSY DANZSY NNP 50458 414 9 : : : 50458 414 10 _ _ NNP 50458 414 11 Annales Annales NNP 50458 414 12 de de NNP 50458 414 13 l'Institut l'Institut NNP 50458 414 14 Pasteur Pasteur NNP 50458 414 15 _ _ NNP 50458 414 16 , , , 50458 414 17 XVI XVI NNP 50458 414 18 , , , 50458 414 19 p. p. NN 50458 414 20 331 331 CD 50458 414 21 . . . 50458 415 1 Some some DT 50458 415 2 recent recent JJ 50458 415 3 experiments experiment NNS 50458 415 4 by by IN 50458 415 5 J. J. NNP 50458 415 6 Martin Martin NNP 50458 415 7 and and CC 50458 415 8 Cherry Cherry NNP 50458 415 9 ( ( -LRB- 50458 415 10 _ _ NNP 50458 415 11 Proceedings Proceedings NNP 50458 415 12 of of IN 50458 415 13 the the DT 50458 415 14 Royal Royal NNP 50458 415 15 Society Society NNP 50458 415 16 _ _ NNP 50458 415 17 , , , 50458 415 18 1898 1898 CD 50458 415 19 , , , 50458 415 20 LXIII LXIII NNP 50458 415 21 , , , 50458 415 22 p. p. NN 50458 415 23 423 423 CD 50458 415 24 ) ) -RRB- 50458 415 25 have have VBP 50458 415 26 clearly clearly RB 50458 415 27 brought bring VBN 50458 415 28 out out RP 50458 415 29 this this DT 50458 415 30 fact fact NN 50458 415 31 . . . 50458 416 1 These these DT 50458 416 2 authors author NNS 50458 416 3 made make VBD 50458 416 4 mixtures mixture NNS 50458 416 5 of of IN 50458 416 6 serpent serpent JJ 50458 416 7 venom venom NN 50458 416 8 with with IN 50458 416 9 its -PRON- PRP$ 50458 416 10 antivenom antivenom NN 50458 416 11 , , , 50458 416 12 which which WDT 50458 416 13 they -PRON- PRP 50458 416 14 filtered filter VBD 50458 416 15 through through IN 50458 416 16 a a DT 50458 416 17 layer layer NN 50458 416 18 of of IN 50458 416 19 gelatin gelatin NN 50458 416 20 , , , 50458 416 21 under under IN 50458 416 22 the the DT 50458 416 23 supposition supposition NN 50458 416 24 that that IN 50458 416 25 , , , 50458 416 26 if if IN 50458 416 27 the the DT 50458 416 28 venom venom NN 50458 416 29 and and CC 50458 416 30 its -PRON- PRP$ 50458 416 31 antivenom antivenom NNS 50458 416 32 were be VBD 50458 416 33 not not RB 50458 416 34 chemically chemically RB 50458 416 35 combined combine VBN 50458 416 36 , , , 50458 416 37 the the DT 50458 416 38 former former JJ 50458 416 39 alone alone RB 50458 416 40 would would MD 50458 416 41 be be VB 50458 416 42 able able JJ 50458 416 43 to to TO 50458 416 44 pass pass VB 50458 416 45 through through RP 50458 416 46 into into IN 50458 416 47 the the DT 50458 416 48 filtrate filtrate JJ 50458 416 49 , , , 50458 416 50 because because IN 50458 416 51 its -PRON- PRP$ 50458 416 52 molecules molecule NNS 50458 416 53 are be VBP 50458 416 54 so so RB 50458 416 55 much much RB 50458 416 56 smaller small JJR 50458 416 57 . . . 50458 417 1 Martin Martin NNP 50458 417 2 and and CC 50458 417 3 Cherry Cherry NNP 50458 417 4 allowed allow VBD 50458 417 5 the the DT 50458 417 6 venom venom NN 50458 417 7 and and CC 50458 417 8 its -PRON- PRP$ 50458 417 9 antivenom antivenom NN 50458 417 10 to to TO 50458 417 11 remain remain VB 50458 417 12 in in IN 50458 417 13 contact contact NN 50458 417 14 for for IN 50458 417 15 varying vary VBG 50458 417 16 periods period NNS 50458 417 17 before before IN 50458 417 18 filtering filter VBG 50458 417 19 . . . 50458 418 1 As as IN 50458 418 2 the the DT 50458 418 3 result result NN 50458 418 4 of of IN 50458 418 5 a a DT 50458 418 6 series series NN 50458 418 7 of of IN 50458 418 8 experiments experiment NNS 50458 418 9 carried carry VBN 50458 418 10 out out RP 50458 418 11 with with IN 50458 418 12 this this DT 50458 418 13 idea idea NN 50458 418 14 , , , 50458 418 15 they -PRON- PRP 50458 418 16 have have VBP 50458 418 17 demonstrated demonstrate VBN 50458 418 18 that that IN 50458 418 19 the the DT 50458 418 20 filtrate filtrate NN 50458 418 21 obtained obtain VBN 50458 418 22 after after IN 50458 418 23 allowing allow VBG 50458 418 24 a a DT 50458 418 25 few few JJ 50458 418 26 minutes minute NNS 50458 418 27 ' ' POS 50458 418 28 contact contact NN 50458 418 29 between between IN 50458 418 30 the the DT 50458 418 31 two two CD 50458 418 32 substances substance NNS 50458 418 33 , , , 50458 418 34 was be VBD 50458 418 35 decidedly decidedly RB 50458 418 36 toxic toxic JJ 50458 418 37 , , , 50458 418 38 while while IN 50458 418 39 that that DT 50458 418 40 obtained obtain VBD 50458 418 41 after after IN 50458 418 42 a a DT 50458 418 43 contact contact NN 50458 418 44 of of IN 50458 418 45 half half PDT 50458 418 46 an an DT 50458 418 47 hour hour NN 50458 418 48 was be VBD 50458 418 49 absolutely absolutely RB 50458 418 50 non non JJ 50458 418 51 - - JJ 50458 418 52 toxic toxic JJ 50458 418 53 . . . 50458 419 1 From from IN 50458 419 2 this this DT 50458 419 3 the the DT 50458 419 4 authors author NNS 50458 419 5 conclude conclude VBP 50458 419 6 that that IN 50458 419 7 the the DT 50458 419 8 antitoxin antitoxin NN 50458 419 9 enters enter VBZ 50458 419 10 into into IN 50458 419 11 chemical chemical NN 50458 419 12 union union NN 50458 419 13 with with IN 50458 419 14 the the DT 50458 419 15 venom venom NN 50458 419 16 , , , 50458 419 17 but but CC 50458 419 18 that that IN 50458 419 19 the the DT 50458 419 20 combination combination NN 50458 419 21 does do VBZ 50458 419 22 not not RB 50458 419 23 take take VB 50458 419 24 place place NN 50458 419 25 immediately immediately RB 50458 419 26 , , , 50458 419 27 and and CC 50458 419 28 requires require VBZ 50458 419 29 a a DT 50458 419 30 certain certain JJ 50458 419 31 length length NN 50458 419 32 of of IN 50458 419 33 time time NN 50458 419 34 for for IN 50458 419 35 its -PRON- PRP$ 50458 419 36 accomplishment accomplishment NN 50458 419 37 . . . 50458 420 1 Ehrlich Ehrlich NNP 50458 420 2 and and CC 50458 420 3 Knorr Knorr NNP 50458 420 4 have have VBP 50458 420 5 demonstrated demonstrate VBN 50458 420 6 that that IN 50458 420 7 the the DT 50458 420 8 neutralization neutralization NN 50458 420 9 is be VBZ 50458 420 10 less less RBR 50458 420 11 rapid rapid JJ 50458 420 12 in in IN 50458 420 13 dilute dilute JJ 50458 420 14 solutions solution NNS 50458 420 15 than than IN 50458 420 16 in in IN 50458 420 17 concentrated concentrated JJ 50458 420 18 ones one NNS 50458 420 19 . . . 50458 421 1 Prof. Prof. NNP 50458 421 2 Svante Svante NNP 50458 421 3 Arrhenius Arrhenius NNP 50458 421 4 has have VBZ 50458 421 5 completed complete VBN 50458 421 6 our -PRON- PRP$ 50458 421 7 knowledge knowledge NN 50458 421 8 regarding regard VBG 50458 421 9 the the DT 50458 421 10 mode mode NN 50458 421 11 of of IN 50458 421 12 combination combination NN 50458 421 13 between between IN 50458 421 14 the the DT 50458 421 15 toxins toxin NNS 50458 421 16 and and CC 50458 421 17 the the DT 50458 421 18 antitoxins antitoxin NNS 50458 421 19 , , , 50458 421 20 by by IN 50458 421 21 demonstrating demonstrate VBG 50458 421 22 the the DT 50458 421 23 occurrence occurrence NN 50458 421 24 of of IN 50458 421 25 limited limited JJ 50458 421 26 reactions reaction NNS 50458 421 27 analogous analogous JJ 50458 421 28 to to IN 50458 421 29 the the DT 50458 421 30 etherification etherification NN 50458 421 31 of of IN 50458 421 32 an an DT 50458 421 33 alcohol alcohol NN 50458 421 34 by by IN 50458 421 35 an an DT 50458 421 36 acid acid NN 50458 421 37 , , , 50458 421 38 and and CC 50458 421 39 in in IN 50458 421 40 such such PDT 50458 421 41 a a DT 50458 421 42 manner manner NN 50458 421 43 that that IN 50458 421 44 there there EX 50458 421 45 always always RB 50458 421 46 exists exist VBZ 50458 421 47 , , , 50458 421 48 in in IN 50458 421 49 a a DT 50458 421 50 mixture mixture NN 50458 421 51 of of IN 50458 421 52 these these DT 50458 421 53 two two CD 50458 421 54 substances substance NNS 50458 421 55 , , , 50458 421 56 a a DT 50458 421 57 certain certain JJ 50458 421 58 quantity quantity NN 50458 421 59 of of IN 50458 421 60 free free JJ 50458 421 61 toxin toxin NN 50458 421 62 and and CC 50458 421 63 antitoxin antitoxin NN 50458 421 64 . . . 50458 422 1 This this DT 50458 422 2 is be VBZ 50458 422 3 an an DT 50458 422 4 important important JJ 50458 422 5 modification modification NN 50458 422 6 of of IN 50458 422 7 the the DT 50458 422 8 general general JJ 50458 422 9 ideas idea NNS 50458 422 10 held hold VBN 50458 422 11 in in IN 50458 422 12 this this DT 50458 422 13 respect respect NN 50458 422 14 . . . 50458 423 1 [ [ -LRB- 50458 423 2 49 49 CD 50458 423 3 ] ] -RRB- 50458 423 4 [ [ -LRB- 50458 423 5 49 49 CD 50458 423 6 ] ] -RRB- 50458 423 7 SVANTE SVANTE NNP 50458 423 8 ARRHENIUS arrheniu NNS 50458 423 9 : : : 50458 423 10 La La NNP 50458 423 11 Physico Physico NNP 50458 423 12 - - HYPH 50458 423 13 chimie chimie NNP 50458 423 14 des des NNP 50458 423 15 Toxines Toxines NNP 50458 423 16 et et NNP 50458 423 17 des des FW 50458 423 18 Antitoxines Antitoxines NNP 50458 423 19 . . . 50458 424 1 _ _ NNP 50458 424 2 Conférences Conférences NNPS 50458 424 3 de de NNP 50458 424 4 la la NNP 50458 424 5 Société Société NNP 50458 424 6 chimique chimique NN 50458 424 7 de de IN 50458 424 8 Paris Paris NNP 50458 424 9 _ _ NNP 50458 424 10 , , , 50458 424 11 May May NNP 50458 424 12 20 20 CD 50458 424 13 , , , 50458 424 14 1904 1904 CD 50458 424 15 . . . 50458 425 1 See see VB 50458 425 2 also also RB 50458 425 3 MADSEN madsen NN 50458 425 4 AND and CC 50458 425 5 ARRHENIUS arrhenius NN 50458 425 6 : : : 50458 425 7 Testkrift testkrift VB 50458 425 8 red red JJ 50458 425 9 indivulsen indivulsen NN 50458 425 10 of of IN 50458 425 11 Stotens Stotens NNP 50458 425 12 Serum Serum NNP 50458 425 13 Institut Institut NNP 50458 425 14 . . . 50458 426 1 Copenhagen Copenhagen NNP 50458 426 2 , , , 50458 426 3 1902 1902 CD 50458 426 4 . . . 50458 427 1 It -PRON- PRP 50458 427 2 appears appear VBZ 50458 427 3 necessary necessary JJ 50458 427 4 to to TO 50458 427 5 bring bring VB 50458 427 6 here here RB 50458 427 7 more more RBR 50458 427 8 clearly clearly RB 50458 427 9 in in IN 50458 427 10 evidence evidence NN 50458 427 11 the the DT 50458 427 12 fact fact NN 50458 427 13 that that IN 50458 427 14 _ _ NNP 50458 427 15 the the DT 50458 427 16 antitoxin antitoxin NN 50458 427 17 inhibits inhibit VBZ 50458 427 18 the the DT 50458 427 19 noxious noxious JJ 50458 427 20 action action NN 50458 427 21 of of IN 50458 427 22 the the DT 50458 427 23 toxin toxin NN 50458 427 24 , , , 50458 427 25 even even RB 50458 427 26 outside outside IN 50458 427 27 the the DT 50458 427 28 living live VBG 50458 427 29 organism organism NN 50458 427 30 , , , 50458 427 31 by by IN 50458 427 32 uniting unite VBG 50458 427 33 with with IN 50458 427 34 it -PRON- PRP 50458 427 35 to to TO 50458 427 36 form form VB 50458 427 37 a a DT 50458 427 38 compound compound NN 50458 427 39 in in IN 50458 427 40 identically identically RB 50458 427 41 the the DT 50458 427 42 same same JJ 50458 427 43 manner manner NN 50458 427 44 as as IN 50458 427 45 when when WRB 50458 427 46 a a DT 50458 427 47 strong strong JJ 50458 427 48 base base NN 50458 427 49 and and CC 50458 427 50 a a DT 50458 427 51 strong strong JJ 50458 427 52 acid acid NN 50458 427 53 are be VBP 50458 427 54 brought bring VBN 50458 427 55 together together RB 50458 427 56 _ _ NNP 50458 427 57 . . . 50458 428 1 As as IN 50458 428 2 we -PRON- PRP 50458 428 3 have have VBP 50458 428 4 seen see VBN 50458 428 5 , , , 50458 428 6 all all PDT 50458 428 7 the the DT 50458 428 8 conditions condition NNS 50458 428 9 of of IN 50458 428 10 environment environment NN 50458 428 11 that that WDT 50458 428 12 favor favor VBP 50458 428 13 or or CC 50458 428 14 retard retard VB 50458 428 15 the the DT 50458 428 16 formation formation NN 50458 428 17 of of IN 50458 428 18 salts salt NNS 50458 428 19 , , , 50458 428 20 in in IN 50458 428 21 a a DT 50458 428 22 like like JJ 50458 428 23 sense sense NN 50458 428 24 influence influence VBP 50458 428 25 the the DT 50458 428 26 neutralization neutralization NN 50458 428 27 of of IN 50458 428 28 the the DT 50458 428 29 toxin toxin NN 50458 428 30 by by IN 50458 428 31 its -PRON- PRP$ 50458 428 32 antitoxin antitoxin NN 50458 428 33 . . . 50458 429 1 = = NFP 50458 429 2 Formation Formation NNP 50458 429 3 of of IN 50458 429 4 Antitoxins.=--Ehrlich Antitoxins.=--Ehrlich NNP 50458 429 5 's 's POS 50458 429 6 theory theory NN 50458 429 7 of of IN 50458 429 8 side side NN 50458 429 9 chains chain NNS 50458 429 10 , , , 50458 429 11 to to TO 50458 429 12 which which WDT 50458 429 13 reference reference NN 50458 429 14 has have VBZ 50458 429 15 already already RB 50458 429 16 been be VBN 50458 429 17 made make VBN 50458 429 18 , , , 50458 429 19 furnishes furnish VBZ 50458 429 20 us -PRON- PRP 50458 429 21 with with IN 50458 429 22 an an DT 50458 429 23 explanation explanation NN 50458 429 24 of of IN 50458 429 25 the the DT 50458 429 26 formation formation NN 50458 429 27 of of IN 50458 429 28 the the DT 50458 429 29 antitoxins antitoxin NNS 50458 429 30 in in IN 50458 429 31 tumors tumor NNS 50458 429 32 . . . 50458 430 1 Let let VB 50458 430 2 us -PRON- PRP 50458 430 3 suppose suppose VB 50458 430 4 that that IN 50458 430 5 , , , 50458 430 6 in in IN 50458 430 7 the the DT 50458 430 8 organism organism NN 50458 430 9 , , , 50458 430 10 a a DT 50458 430 11 cell cell NN 50458 430 12 had have VBD 50458 430 13 come come VBN 50458 430 14 into into IN 50458 430 15 contact contact NN 50458 430 16 only only RB 50458 430 17 with with IN 50458 430 18 certain certain JJ 50458 430 19 toxic toxic JJ 50458 430 20 molecules molecule NNS 50458 430 21 incapable incapable JJ 50458 430 22 of of IN 50458 430 23 compromising compromise VBG 50458 430 24 its -PRON- PRP$ 50458 430 25 life life NN 50458 430 26 , , , 50458 430 27 and and CC 50458 430 28 that that IN 50458 430 29 the the DT 50458 430 30 only only JJ 50458 430 31 result result NN 50458 430 32 was be VBD 50458 430 33 the the DT 50458 430 34 immobilization immobilization NN 50458 430 35 of of IN 50458 430 36 the the DT 50458 430 37 receptors receptor NNS 50458 430 38 which which WDT 50458 430 39 are be VBP 50458 430 40 united united JJ 50458 430 41 with with IN 50458 430 42 the the DT 50458 430 43 haptophore haptophore JJ 50458 430 44 groups group NNS 50458 430 45 of of IN 50458 430 46 the the DT 50458 430 47 opposing oppose VBG 50458 430 48 toxins toxin NNS 50458 430 49 . . . 50458 431 1 It -PRON- PRP 50458 431 2 is be VBZ 50458 431 3 known know VBN 50458 431 4 that that IN 50458 431 5 , , , 50458 431 6 by by IN 50458 431 7 virtue virtue NN 50458 431 8 of of IN 50458 431 9 a a DT 50458 431 10 property property NN 50458 431 11 inherent inherent JJ 50458 431 12 in in IN 50458 431 13 all all DT 50458 431 14 living live VBG 50458 431 15 organisms organism NNS 50458 431 16 , , , 50458 431 17 during during IN 50458 431 18 the the DT 50458 431 19 phenomena phenomenon NNS 50458 431 20 of of IN 50458 431 21 reparation reparation NN 50458 431 22 , , , 50458 431 23 there there EX 50458 431 24 is be VBZ 50458 431 25 generally generally RB 50458 431 26 an an DT 50458 431 27 overproduction overproduction NN 50458 431 28 of of IN 50458 431 29 the the DT 50458 431 30 neoformed neoformed JJ 50458 431 31 parts part NNS 50458 431 32 . . . 50458 432 1 In in IN 50458 432 2 the the DT 50458 432 3 case case NN 50458 432 4 we -PRON- PRP 50458 432 5 here here RB 50458 432 6 speak speak VBP 50458 432 7 of of IN 50458 432 8 , , , 50458 432 9 as as IN 50458 432 10 the the DT 50458 432 11 receptors receptor NNS 50458 432 12 fill fill VBP 50458 432 13 an an DT 50458 432 14 important important JJ 50458 432 15 function function NN 50458 432 16 in in IN 50458 432 17 the the DT 50458 432 18 nutrition nutrition NN 50458 432 19 of of IN 50458 432 20 the the DT 50458 432 21 opposing opposing JJ 50458 432 22 cellular cellular JJ 50458 432 23 elements element NNS 50458 432 24 , , , 50458 432 25 once once IN 50458 432 26 they -PRON- PRP 50458 432 27 become become VBP 50458 432 28 united united JJ 50458 432 29 with with IN 50458 432 30 the the DT 50458 432 31 toxic toxic JJ 50458 432 32 haptophores haptophore NNS 50458 432 33 , , , 50458 432 34 they -PRON- PRP 50458 432 35 become become VBP 50458 432 36 incapable incapable JJ 50458 432 37 of of IN 50458 432 38 filling fill VBG 50458 432 39 their -PRON- PRP$ 50458 432 40 normal normal JJ 50458 432 41 function function NN 50458 432 42 of of IN 50458 432 43 nutrition nutrition NN 50458 432 44 . . . 50458 433 1 Under under IN 50458 433 2 these these DT 50458 433 3 conditions condition NNS 50458 433 4 the the DT 50458 433 5 cells cell NNS 50458 433 6 develop develop VBP 50458 433 7 so so RB 50458 433 8 large large JJ 50458 433 9 a a DT 50458 433 10 quantity quantity NN 50458 433 11 of of IN 50458 433 12 receptors receptor NNS 50458 433 13 that that WDT 50458 433 14 , , , 50458 433 15 filling fill VBG 50458 433 16 the the DT 50458 433 17 cells cell NNS 50458 433 18 , , , 50458 433 19 and and CC 50458 433 20 not not RB 50458 433 21 finding find VBG 50458 433 22 any any DT 50458 433 23 more more JJR 50458 433 24 room room NN 50458 433 25 , , , 50458 433 26 they -PRON- PRP 50458 433 27 spread spread VBD 50458 433 28 into into IN 50458 433 29 the the DT 50458 433 30 blood blood NN 50458 433 31 and and CC 50458 433 32 other other JJ 50458 433 33 liquids liquid NNS 50458 433 34 of of IN 50458 433 35 the the DT 50458 433 36 organism organism NN 50458 433 37 . . . 50458 434 1 Under under IN 50458 434 2 these these DT 50458 434 3 conditions condition NNS 50458 434 4 , , , 50458 434 5 every every DT 50458 434 6 new new JJ 50458 434 7 injection injection NN 50458 434 8 of of IN 50458 434 9 toxin toxin NN 50458 434 10 into into IN 50458 434 11 the the DT 50458 434 12 organism organism NN 50458 434 13 is be VBZ 50458 434 14 absorbed absorb VBN 50458 434 15 into into IN 50458 434 16 the the DT 50458 434 17 blood blood NN 50458 434 18 where where WRB 50458 434 19 it -PRON- PRP 50458 434 20 meets meet VBZ 50458 434 21 with with IN 50458 434 22 the the DT 50458 434 23 free free JJ 50458 434 24 receptors receptor NNS 50458 434 25 which which WDT 50458 434 26 possess possess VBP 50458 434 27 great great JJ 50458 434 28 avidity avidity NN 50458 434 29 for for IN 50458 434 30 the the DT 50458 434 31 haptophore haptophore JJ 50458 434 32 group group NN 50458 434 33 of of IN 50458 434 34 its -PRON- PRP$ 50458 434 35 molecule molecule NN 50458 434 36 , , , 50458 434 37 and and CC 50458 434 38 the the DT 50458 434 39 two two CD 50458 434 40 groups group NNS 50458 434 41 immediately immediately RB 50458 434 42 unite unite VBP 50458 434 43 , , , 50458 434 44 before before IN 50458 434 45 the the DT 50458 434 46 haptophore haptophore JJ 50458 434 47 group group NN 50458 434 48 of of IN 50458 434 49 the the DT 50458 434 50 toxin toxin NN 50458 434 51 has have VBZ 50458 434 52 been be VBN 50458 434 53 able able JJ 50458 434 54 to to TO 50458 434 55 attack attack VB 50458 434 56 and and CC 50458 434 57 intoxicate intoxicate VB 50458 434 58 a a DT 50458 434 59 cellular cellular JJ 50458 434 60 element element NN 50458 434 61 . . . 50458 435 1 We -PRON- PRP 50458 435 2 thus thus RB 50458 435 3 see see VBP 50458 435 4 that that IN 50458 435 5 the the DT 50458 435 6 receptors receptor NNS 50458 435 7 which which WDT 50458 435 8 , , , 50458 435 9 when when WRB 50458 435 10 in in IN 50458 435 11 a a DT 50458 435 12 free free JJ 50458 435 13 state state NN 50458 435 14 in in IN 50458 435 15 tumors tumor NNS 50458 435 16 , , , 50458 435 17 play play VB 50458 435 18 the the DT 50458 435 19 rôle rôle NN 50458 435 20 of of IN 50458 435 21 antitoxics antitoxic NNS 50458 435 22 or or CC 50458 435 23 antitoxins antitoxin NNS 50458 435 24 , , , 50458 435 25 become become VB 50458 435 26 , , , 50458 435 27 within within IN 50458 435 28 the the DT 50458 435 29 cellular cellular JJ 50458 435 30 elements element NNS 50458 435 31 themselves -PRON- PRP 50458 435 32 , , , 50458 435 33 the the DT 50458 435 34 vehicle vehicle NN 50458 435 35 of of IN 50458 435 36 intoxications intoxication NNS 50458 435 37 . . . 50458 436 1 Figuratively figuratively RB 50458 436 2 speaking speak VBG 50458 436 3 , , , 50458 436 4 so so RB 50458 436 5 long long RB 50458 436 6 as as IN 50458 436 7 these these DT 50458 436 8 fixators fixator NNS 50458 436 9 are be VBP 50458 436 10 attached attach VBN 50458 436 11 to to IN 50458 436 12 the the DT 50458 436 13 molecule molecule NN 50458 436 14 of of IN 50458 436 15 the the DT 50458 436 16 living living NN 50458 436 17 protoplasm protoplasm NN 50458 436 18 they -PRON- PRP 50458 436 19 attract attract VBP 50458 436 20 the the DT 50458 436 21 toxin toxin NN 50458 436 22 . . . 50458 437 1 According accord VBG 50458 437 2 to to IN 50458 437 3 this this DT 50458 437 4 ingenious ingenious JJ 50458 437 5 conception conception NN 50458 437 6 , , , 50458 437 7 the the DT 50458 437 8 formation formation NN 50458 437 9 of of IN 50458 437 10 antitoxins antitoxin NNS 50458 437 11 is be VBZ 50458 437 12 hence hence RB 50458 437 13 absolutely absolutely RB 50458 437 14 independent independent JJ 50458 437 15 of of IN 50458 437 16 the the DT 50458 437 17 action action NN 50458 437 18 of of IN 50458 437 19 the the DT 50458 437 20 toxophore toxophore NN 50458 437 21 elements element NNS 50458 437 22 on on IN 50458 437 23 the the DT 50458 437 24 cellular cellular JJ 50458 437 25 elements element NNS 50458 437 26 , , , 50458 437 27 and and CC 50458 437 28 it -PRON- PRP 50458 437 29 suffices suffice VBZ 50458 437 30 that that IN 50458 437 31 these these DT 50458 437 32 possess possess VBP 50458 437 33 receptors receptor NNS 50458 437 34 or or CC 50458 437 35 side side NN 50458 437 36 chains chain NNS 50458 437 37 capable capable JJ 50458 437 38 of of IN 50458 437 39 uniting unite VBG 50458 437 40 with with IN 50458 437 41 the the DT 50458 437 42 haptophore haptophore JJ 50458 437 43 groups group NNS 50458 437 44 of of IN 50458 437 45 the the DT 50458 437 46 toxin toxin NN 50458 437 47 . . . 50458 438 1 This this DT 50458 438 2 explains explain VBZ 50458 438 3 why why WRB 50458 438 4 it -PRON- PRP 50458 438 5 has have VBZ 50458 438 6 been be VBN 50458 438 7 possible possible JJ 50458 438 8 to to TO 50458 438 9 produce produce VB 50458 438 10 antitoxins antitoxin NNS 50458 438 11 from from IN 50458 438 12 toxins toxin NNS 50458 438 13 which which WDT 50458 438 14 have have VBP 50458 438 15 lost lose VBN 50458 438 16 some some DT 50458 438 17 of of IN 50458 438 18 their -PRON- PRP$ 50458 438 19 toxic toxic JJ 50458 438 20 properties property NNS 50458 438 21 , , , 50458 438 22 but but CC 50458 438 23 which which WDT 50458 438 24 have have VBP 50458 438 25 preserved preserve VBN 50458 438 26 their -PRON- PRP$ 50458 438 27 property property NN 50458 438 28 of of IN 50458 438 29 uniting unite VBG 50458 438 30 with with IN 50458 438 31 antitoxic antitoxic JJ 50458 438 32 substances substance NNS 50458 438 33 . . . 50458 439 1 Ehrlich Ehrlich NNP 50458 439 2 gives give VBZ 50458 439 3 the the DT 50458 439 4 name name NN 50458 439 5 _ _ NNP 50458 439 6 toxoids toxoids NNPS 50458 439 7 _ _ NNP 50458 439 8 to to IN 50458 439 9 those those DT 50458 439 10 modified modify VBN 50458 439 11 toxins toxin NNS 50458 439 12 that that WDT 50458 439 13 have have VBP 50458 439 14 lost lose VBN 50458 439 15 their -PRON- PRP$ 50458 439 16 toxophore toxophore NN 50458 439 17 groups group NNS 50458 439 18 , , , 50458 439 19 while while IN 50458 439 20 the the DT 50458 439 21 haptophore haptophore NN 50458 439 22 group group NN 50458 439 23 , , , 50458 439 24 the the DT 50458 439 25 producer producer NN 50458 439 26 of of IN 50458 439 27 the the DT 50458 439 28 immunizing immunize VBG 50458 439 29 substance substance NN 50458 439 30 , , , 50458 439 31 is be VBZ 50458 439 32 still still RB 50458 439 33 preserved preserve VBN 50458 439 34 intact intact JJ 50458 439 35 . . . 50458 440 1 According accord VBG 50458 440 2 to to IN 50458 440 3 Metchnikoff Metchnikoff NNP 50458 440 4 's 's POS 50458 440 5 theory theory NN 50458 440 6 , , , 50458 440 7 which which WDT 50458 440 8 is be VBZ 50458 440 9 very very RB 50458 440 10 similar similar JJ 50458 440 11 , , , 50458 440 12 it -PRON- PRP 50458 440 13 seems seem VBZ 50458 440 14 quite quite RB 50458 440 15 possible possible JJ 50458 440 16 that that IN 50458 440 17 the the DT 50458 440 18 phagocytes phagocyte NNS 50458 440 19 , , , 50458 440 20 thanks thank NNS 50458 440 21 to to IN 50458 440 22 the the DT 50458 440 23 facility facility NN 50458 440 24 with with IN 50458 440 25 which which WDT 50458 440 26 they -PRON- PRP 50458 440 27 absorb absorb VBP 50458 440 28 poisons poison NNS 50458 440 29 , , , 50458 440 30 occupy occupy VBP 50458 440 31 an an DT 50458 440 32 important important JJ 50458 440 33 place place NN 50458 440 34 as as IN 50458 440 35 producers producer NNS 50458 440 36 of of IN 50458 440 37 antitoxins antitoxin NNS 50458 440 38 . . . 50458 441 1 It -PRON- PRP 50458 441 2 has have VBZ 50458 441 3 not not RB 50458 441 4 been be VBN 50458 441 5 possible possible JJ 50458 441 6 so so RB 50458 441 7 far far RB 50458 441 8 to to TO 50458 441 9 verify verify VB 50458 441 10 this this DT 50458 441 11 theory theory NN 50458 441 12 in in IN 50458 441 13 our -PRON- PRP$ 50458 441 14 at at IN 50458 441 15 present present JJ 50458 441 16 imperfect imperfect JJ 50458 441 17 knowledge knowledge NN 50458 441 18 regarding regard VBG 50458 441 19 this this DT 50458 441 20 subject subject NN 50458 441 21 . . . 50458 442 1 The the DT 50458 442 2 domain domain NN 50458 442 3 of of IN 50458 442 4 immunity immunity NN 50458 442 5 has have VBZ 50458 442 6 , , , 50458 442 7 however however RB 50458 442 8 , , , 50458 442 9 made make VBD 50458 442 10 brilliant brilliant JJ 50458 442 11 conquests conquest NNS 50458 442 12 during during IN 50458 442 13 these these DT 50458 442 14 last last JJ 50458 442 15 few few JJ 50458 442 16 years year NNS 50458 442 17 , , , 50458 442 18 so so IN 50458 442 19 that that IN 50458 442 20 we -PRON- PRP 50458 442 21 should should MD 50458 442 22 not not RB 50458 442 23 despair despair VB 50458 442 24 of of IN 50458 442 25 arriving arrive VBG 50458 442 26 at at IN 50458 442 27 a a DT 50458 442 28 definite definite JJ 50458 442 29 solution solution NN 50458 442 30 before before IN 50458 442 31 long long RB 50458 442 32 . . . 50458 443 1 In in IN 50458 443 2 the the DT 50458 443 3 vaccinated vaccinated JJ 50458 443 4 animal animal NN 50458 443 5 the the DT 50458 443 6 antitoxin antitoxin NN 50458 443 7 is be VBZ 50458 443 8 reproduced reproduce VBN 50458 443 9 , , , 50458 443 10 and and CC 50458 443 11 it -PRON- PRP 50458 443 12 is be VBZ 50458 443 13 possible possible JJ 50458 443 14 to to TO 50458 443 15 obtain obtain VB 50458 443 16 several several JJ 50458 443 17 times time NNS 50458 443 18 , , , 50458 443 19 from from IN 50458 443 20 the the DT 50458 443 21 vaccinated vaccinated JJ 50458 443 22 animals animal NNS 50458 443 23 , , , 50458 443 24 successive successive JJ 50458 443 25 portions portion NNS 50458 443 26 of of IN 50458 443 27 antitoxic antitoxic NN 50458 443 28 serum serum NN 50458 443 29 . . . 50458 444 1 [ [ -LRB- 50458 444 2 50 50 CD 50458 444 3 ] ] -RRB- 50458 444 4 The the DT 50458 444 5 protective protective JJ 50458 444 6 power power NN 50458 444 7 of of IN 50458 444 8 these these DT 50458 444 9 antitoxins antitoxin NNS 50458 444 10 is be VBZ 50458 444 11 absolutely absolutely RB 50458 444 12 marvelous marvelous JJ 50458 444 13 . . . 50458 445 1 An an DT 50458 445 2 animal animal NN 50458 445 3 accustomed accustom VBN 50458 445 4 gradually gradually RB 50458 445 5 to to IN 50458 445 6 the the DT 50458 445 7 tetanic tetanic JJ 50458 445 8 virus virus NN 50458 445 9 yields yield VBZ 50458 445 10 a a DT 50458 445 11 serum serum NN 50458 445 12 containing contain VBG 50458 445 13 an an DT 50458 445 14 antitoxin antitoxin NN 50458 445 15 a a DT 50458 445 16 thousand thousand CD 50458 445 17 times time NNS 50458 445 18 more more RBR 50458 445 19 active active JJ 50458 445 20 than than IN 50458 445 21 the the DT 50458 445 22 virus virus NN 50458 445 23 . . . 50458 446 1 [ [ -LRB- 50458 446 2 50 50 CD 50458 446 3 ] ] -RRB- 50458 446 4 CH CH NNP 50458 446 5 . . . 50458 447 1 SALMONSEN SALMONSEN NNP 50458 447 2 et et NNP 50458 447 3 TH TH NNP 50458 447 4 . . . 50458 448 1 MADSEN MADSEN NNP 50458 448 2 : : : 50458 448 3 Réproduction Réproduction NNP 50458 448 4 de de IN 50458 448 5 la la NNP 50458 448 6 substance substance NN 50458 448 7 antitoxique antitoxique NNP 50458 448 8 . . . 50458 449 1 _ _ NNP 50458 449 2 Ann Ann NNP 50458 449 3 . . . 50458 450 1 Inst inst RB 50458 450 2 . . . 50458 451 1 Pasteur Pasteur NNP 50458 451 2 _ _ NNP 50458 451 3 , , , 50458 451 4 XII XII NNP 50458 451 5 , , , 50458 451 6 p. p. NN 50458 451 7 762 762 CD 50458 451 8 . . . 50458 452 1 ROUX ROUX NNP 50458 452 2 et et NNP 50458 452 3 VAILLARD VAILLARD NNP 50458 452 4 : : : 50458 452 5 _ _ NNP 50458 452 6 Ibid Ibid NNP 50458 452 7 . . . 50458 452 8 _ _ NNP 50458 452 9 , , , 50458 452 10 1893 1893 CD 50458 452 11 , , , 50458 452 12 p. p. NN 50458 452 13 83 83 CD 50458 452 14 . . . 50458 453 1 According accord VBG 50458 453 2 to to IN 50458 453 3 Vaillard Vaillard NNP 50458 453 4 , , , 50458 453 5 a a DT 50458 453 6 quintillionth quintillionth NN 50458 453 7 of of IN 50458 453 8 a a DT 50458 453 9 cubic cubic JJ 50458 453 10 centimeter centimeter NN 50458 453 11 of of IN 50458 453 12 this this DT 50458 453 13 antitetanic antitetanic JJ 50458 453 14 serum serum NN 50458 453 15 suffices suffice VBZ 50458 453 16 to to TO 50458 453 17 preserve preserve VB 50458 453 18 one one CD 50458 453 19 gramme gramme NN 50458 453 20 of of IN 50458 453 21 living living NN 50458 453 22 mouse mouse NN 50458 453 23 from from IN 50458 453 24 the the DT 50458 453 25 effects effect NNS 50458 453 26 of of IN 50458 453 27 a a DT 50458 453 28 dose dose NN 50458 453 29 of of IN 50458 453 30 tetanic tetanic JJ 50458 453 31 serum serum NN 50458 453 32 that that WDT 50458 453 33 would would MD 50458 453 34 otherwise otherwise RB 50458 453 35 be be VB 50458 453 36 surely surely RB 50458 453 37 fatal fatal JJ 50458 453 38 . . . 50458 454 1 In in IN 50458 454 2 the the DT 50458 454 3 animal animal NN 50458 454 4 , , , 50458 454 5 the the DT 50458 454 6 antitoxins antitoxin NNS 50458 454 7 are be VBP 50458 454 8 eliminated eliminate VBN 50458 454 9 mostly mostly RB 50458 454 10 by by IN 50458 454 11 the the DT 50458 454 12 fluids fluid NNS 50458 454 13 of of IN 50458 454 14 the the DT 50458 454 15 body body NN 50458 454 16 , , , 50458 454 17 and and CC 50458 454 18 particularly particularly RB 50458 454 19 by by IN 50458 454 20 the the DT 50458 454 21 urine urine NN 50458 454 22 . . . 50458 455 1 Ehrlich Ehrlich NNP 50458 455 2 has have VBZ 50458 455 3 demonstrated demonstrate VBN 50458 455 4 that that IN 50458 455 5 they -PRON- PRP 50458 455 6 also also RB 50458 455 7 pass pass VBP 50458 455 8 into into IN 50458 455 9 the the DT 50458 455 10 milk milk NN 50458 455 11 , , , 50458 455 12 and and CC 50458 455 13 this this DT 50458 455 14 fact fact NN 50458 455 15 is be VBZ 50458 455 16 confirmed confirm VBN 50458 455 17 by by IN 50458 455 18 a a DT 50458 455 19 large large JJ 50458 455 20 number number NN 50458 455 21 of of IN 50458 455 22 observers observer NNS 50458 455 23 . . . 50458 456 1 It -PRON- PRP 50458 456 2 explains explain VBZ 50458 456 3 the the DT 50458 456 4 immunity immunity NN 50458 456 5 acquired acquire VBN 50458 456 6 by by IN 50458 456 7 nurslings nursling NNS 50458 456 8 , , , 50458 456 9 and and CC 50458 456 10 which which WDT 50458 456 11 is be VBZ 50458 456 12 transmitted transmit VBN 50458 456 13 by by IN 50458 456 14 the the DT 50458 456 15 milk milk NN 50458 456 16 . . . 50458 457 1 = = NFP 50458 457 2 Serotherapy.=--The serotherapy.=--the CD 50458 457 3 search search NN 50458 457 4 for for IN 50458 457 5 antitoxins antitoxin NNS 50458 457 6 and and CC 50458 457 7 their -PRON- PRP$ 50458 457 8 rôle rôle NNS 50458 457 9 in in IN 50458 457 10 the the DT 50458 457 11 etiology etiology NN 50458 457 12 of of IN 50458 457 13 infectious infectious JJ 50458 457 14 diseases disease NNS 50458 457 15 are be VBP 50458 457 16 fundamental fundamental JJ 50458 457 17 points point NNS 50458 457 18 in in IN 50458 457 19 actual actual JJ 50458 457 20 therapy therapy NN 50458 457 21 . . . 50458 458 1 It -PRON- PRP 50458 458 2 has have VBZ 50458 458 3 been be VBN 50458 458 4 demonstrated demonstrate VBN 50458 458 5 that that IN 50458 458 6 the the DT 50458 458 7 serums serum NNS 50458 458 8 of of IN 50458 458 9 certain certain JJ 50458 458 10 vaccinated vaccinated JJ 50458 458 11 animals animal NNS 50458 458 12 enjoy enjoy VBP 50458 458 13 very very RB 50458 458 14 extended extended JJ 50458 458 15 antitoxic antitoxic NN 50458 458 16 therapeutic therapeutic JJ 50458 458 17 properties property NNS 50458 458 18 ; ; : 50458 458 19 for for IN 50458 458 20 instance instance NN 50458 458 21 , , , 50458 458 22 the the DT 50458 458 23 serum serum NN 50458 458 24 of of IN 50458 458 25 vaccinated vaccinated JJ 50458 458 26 rabbits rabbit NNS 50458 458 27 is be VBZ 50458 458 28 an an DT 50458 458 29 antivenom antivenom NN 50458 458 30 towards towards IN 50458 458 31 erysipelas erysipela NNS 50458 458 32 ; ; : 50458 458 33 and and CC 50458 458 34 the the DT 50458 458 35 sterilized sterilize VBN 50458 458 36 cultures culture NNS 50458 458 37 of of IN 50458 458 38 the the DT 50458 458 39 pneumococcus pneumococcus NN 50458 458 40 or or CC 50458 458 41 of of IN 50458 458 42 the the DT 50458 458 43 Bacillus Bacillus NNP 50458 458 44 pyocyaneus pyocyaneus NN 50458 458 45 prevents prevent VBZ 50458 458 46 infection infection NN 50458 458 47 of of IN 50458 458 48 carbuncle carbuncle NN 50458 458 49 ( ( -LRB- 50458 458 50 anthrax anthrax NN 50458 458 51 ) ) -RRB- 50458 458 52 . . . 50458 459 1 The the DT 50458 459 2 antivenomous antivenomous JJ 50458 459 3 serum serum NN 50458 459 4 of of IN 50458 459 5 the the DT 50458 459 6 ass ass NN 50458 459 7 immunized immunize VBN 50458 459 8 by by IN 50458 459 9 injections injection NNS 50458 459 10 of of IN 50458 459 11 increasing increase VBG 50458 459 12 doses dose NNS 50458 459 13 of of IN 50458 459 14 the the DT 50458 459 15 venom venom NN 50458 459 16 of of IN 50458 459 17 the the DT 50458 459 18 terrible terrible JJ 50458 459 19 naja naja NNP 50458 459 20 is be VBZ 50458 459 21 a a DT 50458 459 22 perfect perfect JJ 50458 459 23 prophylactic prophylactic JJ 50458 459 24 and and CC 50458 459 25 curative curative JJ 50458 459 26 , , , 50458 459 27 not not RB 50458 459 28 only only RB 50458 459 29 as as IN 50458 459 30 regards regard VBZ 50458 459 31 the the DT 50458 459 32 venom venom NN 50458 459 33 of of IN 50458 459 34 this this DT 50458 459 35 serpent serpent NN 50458 459 36 , , , 50458 459 37 but but CC 50458 459 38 also also RB 50458 459 39 against against IN 50458 459 40 that that DT 50458 459 41 of of IN 50458 459 42 the the DT 50458 459 43 crotalus crotalus NN 50458 459 44 , , , 50458 459 45 trigonocephalus trigonocephalus NN 50458 459 46 , , , 50458 459 47 and and CC 50458 459 48 viper viper NN 50458 459 49 . . . 50458 460 1 We -PRON- PRP 50458 460 2 shall shall MD 50458 460 3 take take VB 50458 460 4 up up RP 50458 460 5 the the DT 50458 460 6 study study NN 50458 460 7 of of IN 50458 460 8 serotherapeutics serotherapeutic NNS 50458 460 9 in in IN 50458 460 10 another another DT 50458 460 11 volume volume NN 50458 460 12 of of IN 50458 460 13 this this DT 50458 460 14 collection collection NN 50458 460 15 . . . 50458 461 1 PART PART NNP 50458 461 2 II ii CD 50458 461 3 . . . 50458 462 1 _ _ NNP 50458 462 2 THE the DT 50458 462 3 TOXINS TOXINS NNP 50458 462 4 PROPER proper NN 50458 462 5 . . . 50458 462 6 _ _ NNP 50458 462 7 CHAPTER CHAPTER NNP 50458 462 8 III III NNP 50458 462 9 . . . 50458 463 1 I. I. NNP 50458 464 1 VEGETABLE VEGETABLE NNP 50458 464 2 AND and CC 50458 464 3 ANIMAL ANIMAL NNP 50458 464 4 TOXINS toxin NNS 50458 464 5 . . . 50458 465 1 The the DT 50458 465 2 vegetable vegetable NN 50458 465 3 toxins toxin NNS 50458 465 4 possess possess VBP 50458 465 5 the the DT 50458 465 6 characteristic characteristic JJ 50458 465 7 property property NN 50458 465 8 of of IN 50458 465 9 being be VBG 50458 465 10 innocuous innocuous JJ 50458 465 11 , , , 50458 465 12 and and CC 50458 465 13 of of IN 50458 465 14 being be VBG 50458 465 15 almost almost RB 50458 465 16 completely completely RB 50458 465 17 devoid devoid JJ 50458 465 18 of of IN 50458 465 19 poisonousness poisonousness NN 50458 465 20 , , , 50458 465 21 when when WRB 50458 465 22 they -PRON- PRP 50458 465 23 are be VBP 50458 465 24 absorbed absorb VBN 50458 465 25 by by IN 50458 465 26 the the DT 50458 465 27 intestines intestine NNS 50458 465 28 ; ; : 50458 465 29 we -PRON- PRP 50458 465 30 can can MD 50458 465 31 see see VB 50458 465 32 , , , 50458 465 33 from from IN 50458 465 34 this this DT 50458 465 35 , , , 50458 465 36 how how WRB 50458 465 37 greatly greatly RB 50458 465 38 they -PRON- PRP 50458 465 39 differ differ VBP 50458 465 40 from from IN 50458 465 41 the the DT 50458 465 42 poisons poison NNS 50458 465 43 proper proper JJ 50458 465 44 . . . 50458 466 1 [ [ -LRB- 50458 466 2 51 51 CD 50458 466 3 ] ] -RRB- 50458 466 4 [ [ -LRB- 50458 466 5 51 51 CD 50458 466 6 ] ] -RRB- 50458 466 7 It -PRON- PRP 50458 466 8 is be VBZ 50458 466 9 understood understand VBN 50458 466 10 that that IN 50458 466 11 the the DT 50458 466 12 active active JJ 50458 466 13 principles principle NNS 50458 466 14 of of IN 50458 466 15 mushrooms mushroom NNS 50458 466 16 are be VBP 50458 466 17 not not RB 50458 466 18 comprised comprise VBN 50458 466 19 under under IN 50458 466 20 this this DT 50458 466 21 definition definition NN 50458 466 22 , , , 50458 466 23 but but CC 50458 466 24 they -PRON- PRP 50458 466 25 will will MD 50458 466 26 be be VB 50458 466 27 studied study VBN 50458 466 28 under under IN 50458 466 29 the the DT 50458 466 30 next next JJ 50458 466 31 heading heading NN 50458 466 32 . . . 50458 467 1 The the DT 50458 467 2 vegetable vegetable NN 50458 467 3 toxins toxin NNS 50458 467 4 known know VBN 50458 467 5 are be VBP 50458 467 6 quite quite RB 50458 467 7 numerous numerous JJ 50458 467 8 ; ; : 50458 467 9 nevertheless nevertheless RB 50458 467 10 our -PRON- PRP$ 50458 467 11 knowledge knowledge NN 50458 467 12 regarding regard VBG 50458 467 13 them -PRON- PRP 50458 467 14 is be VBZ 50458 467 15 very very RB 50458 467 16 incomplete incomplete JJ 50458 467 17 . . . 50458 468 1 Our -PRON- PRP$ 50458 468 2 review review NN 50458 468 3 of of IN 50458 468 4 them -PRON- PRP 50458 468 5 will will MD 50458 468 6 be be VB 50458 468 7 chiefly chiefly RB 50458 468 8 descriptive descriptive JJ 50458 468 9 . . . 50458 469 1 Many many JJ 50458 469 2 of of IN 50458 469 3 the the DT 50458 469 4 leguminous leguminous JJ 50458 469 5 plants plant NNS 50458 469 6 are be VBP 50458 469 7 poisonous poisonous JJ 50458 469 8 , , , 50458 469 9 either either CC 50458 469 10 because because IN 50458 469 11 of of IN 50458 469 12 emanations emanation NNS 50458 469 13 exhaled exhale VBN 50458 469 14 by by IN 50458 469 15 them -PRON- PRP 50458 469 16 , , , 50458 469 17 or or CC 50458 469 18 by by IN 50458 469 19 reason reason NN 50458 469 20 of of IN 50458 469 21 their -PRON- PRP$ 50458 469 22 alkaloids alkaloid NNS 50458 469 23 , , , 50458 469 24 or or CC 50458 469 25 because because IN 50458 469 26 of of IN 50458 469 27 some some DT 50458 469 28 toxins toxin NNS 50458 469 29 contained contain VBN 50458 469 30 in in IN 50458 469 31 them -PRON- PRP 50458 469 32 . . . 50458 470 1 We -PRON- PRP 50458 470 2 shall shall MD 50458 470 3 commence commence VB 50458 470 4 with with IN 50458 470 5 these these DT 50458 470 6 . . . 50458 471 1 = = NFP 50458 471 2 Abrin.=--This Abrin.=--This NNP 50458 471 3 toxin toxin NN 50458 471 4 , , , 50458 471 5 which which WDT 50458 471 6 was be VBD 50458 471 7 studied study VBN 50458 471 8 in in IN 50458 471 9 particular particular JJ 50458 471 10 by by IN 50458 471 11 Warden Warden NNP 50458 471 12 and and CC 50458 471 13 Waddell,[52 Waddell,[52 . 50458 471 14 ] ] -RRB- 50458 471 15 then then RB 50458 471 16 by by IN 50458 471 17 Kobert[53 kobert[53 CD 50458 471 18 ] ] -RRB- 50458 471 19 and and CC 50458 471 20 de de NNP 50458 471 21 Hellin,[54 Hellin,[54 NNP 50458 471 22 ] ] -RRB- 50458 471 23 is be VBZ 50458 471 24 found find VBN 50458 471 25 in in IN 50458 471 26 the the DT 50458 471 27 fruit fruit NN 50458 471 28 of of IN 50458 471 29 the the DT 50458 471 30 Leguminosæ Leguminosæ NNP 50458 471 31 , , , 50458 471 32 Abrus Abrus NNP 50458 471 33 precatorius precatorius NN 50458 471 34 ( ( -LRB- 50458 471 35 wild wild JJ 50458 471 36 licorice licorice NN 50458 471 37 , , , 50458 471 38 or or CC 50458 471 39 jequirity jequirity NN 50458 471 40 ) ) -RRB- 50458 471 41 . . . 50458 472 1 Its -PRON- PRP$ 50458 472 2 name name NN 50458 472 3 was be VBD 50458 472 4 given give VBN 50458 472 5 it -PRON- PRP 50458 472 6 by by IN 50458 472 7 Warden Warden NNP 50458 472 8 and and CC 50458 472 9 Waddell Waddell NNP 50458 472 10 , , , 50458 472 11 who who WP 50458 472 12 discovered discover VBD 50458 472 13 both both CC 50458 472 14 its -PRON- PRP$ 50458 472 15 toxic toxic JJ 50458 472 16 nature nature NN 50458 472 17 and and CC 50458 472 18 the the DT 50458 472 19 vegetable vegetable NN 50458 472 20 toxin toxin NN 50458 472 21 ; ; : 50458 472 22 the the DT 50458 472 23 toxin toxin NN 50458 472 24 is be VBZ 50458 472 25 found find VBN 50458 472 26 only only RB 50458 472 27 in in IN 50458 472 28 the the DT 50458 472 29 seeds seed NNS 50458 472 30 . . . 50458 473 1 To to TO 50458 473 2 extract extract VB 50458 473 3 it -PRON- PRP 50458 473 4 , , , 50458 473 5 the the DT 50458 473 6 seeds seed NNS 50458 473 7 are be VBP 50458 473 8 macerated macerate VBN 50458 473 9 in in IN 50458 473 10 water water NN 50458 473 11 , , , 50458 473 12 and and CC 50458 473 13 the the DT 50458 473 14 solution solution NN 50458 473 15 filtered filter VBN 50458 473 16 and and CC 50458 473 17 precipitated precipitate VBN 50458 473 18 with with IN 50458 473 19 alcohol alcohol NN 50458 473 20 ; ; : 50458 473 21 the the DT 50458 473 22 precipitate precipitate NN 50458 473 23 which which WDT 50458 473 24 forms form NNS 50458 473 25 is be VBZ 50458 473 26 collected collect VBN 50458 473 27 and and CC 50458 473 28 dissolved dissolve VBN 50458 473 29 in in IN 50458 473 30 distilled distilled JJ 50458 473 31 water water NN 50458 473 32 , , , 50458 473 33 from from IN 50458 473 34 which which WDT 50458 473 35 it -PRON- PRP 50458 473 36 is be VBZ 50458 473 37 again again RB 50458 473 38 precipitated precipitate VBN 50458 473 39 by by IN 50458 473 40 adding add VBG 50458 473 41 powdered powder VBN 50458 473 42 ammonium ammonium NN 50458 473 43 sulphate sulphate NN 50458 473 44 . . . 50458 474 1 The the DT 50458 474 2 precipitate precipitate NN 50458 474 3 is be VBZ 50458 474 4 then then RB 50458 474 5 collected collect VBN 50458 474 6 and and CC 50458 474 7 submitted submit VBN 50458 474 8 to to IN 50458 474 9 dialysis dialysis VB 50458 474 10 in in IN 50458 474 11 order order NN 50458 474 12 to to TO 50458 474 13 eliminate eliminate VB 50458 474 14 the the DT 50458 474 15 ammonium ammonium NN 50458 474 16 sulphate sulphate NN 50458 474 17 . . . 50458 475 1 The the DT 50458 475 2 abrin abrin NN 50458 475 3 so so RB 50458 475 4 obtained obtain VBD 50458 475 5 forms form NNS 50458 475 6 an an DT 50458 475 7 albuminoid albuminoid NN 50458 475 8 substance[55 substance[55 NN 50458 475 9 ] ] -RRB- 50458 475 10 stable stable JJ 50458 475 11 at at IN 50458 475 12 100 100 CD 50458 475 13 ° ° NNS 50458 475 14 C. C. NNP 50458 475 15 , , , 50458 475 16 and and CC 50458 475 17 possessing possess VBG 50458 475 18 rotatory rotatory JJ 50458 475 19 power power NN 50458 475 20 ; ; : 50458 475 21 it -PRON- PRP 50458 475 22 liquefies liquefy VBZ 50458 475 23 starch starch NN 50458 475 24 paste paste NN 50458 475 25 , , , 50458 475 26 and and CC 50458 475 27 is be VBZ 50458 475 28 extremely extremely RB 50458 475 29 toxic toxic JJ 50458 475 30 . . . 50458 476 1 One one CD 50458 476 2 milligramme milligramme NN 50458 476 3 suffices suffice VBZ 50458 476 4 to to TO 50458 476 5 kill kill VB 50458 476 6 a a DT 50458 476 7 rabbit rabbit NN 50458 476 8 within within IN 50458 476 9 several several JJ 50458 476 10 hours hour NNS 50458 476 11 . . . 50458 477 1 It -PRON- PRP 50458 477 2 must must MD 50458 477 3 be be VB 50458 477 4 observed observe VBN 50458 477 5 , , , 50458 477 6 however however RB 50458 477 7 , , , 50458 477 8 that that IN 50458 477 9 , , , 50458 477 10 as as IN 50458 477 11 is be VBZ 50458 477 12 the the DT 50458 477 13 case case NN 50458 477 14 with with IN 50458 477 15 all all PDT 50458 477 16 the the DT 50458 477 17 toxins toxin NNS 50458 477 18 , , , 50458 477 19 abrin abrin NNP 50458 477 20 acts act VBZ 50458 477 21 or or CC 50458 477 22 kills kill VBZ 50458 477 23 only only RB 50458 477 24 after after IN 50458 477 25 a a DT 50458 477 26 period period NN 50458 477 27 of of IN 50458 477 28 incubation incubation NN 50458 477 29 which which WDT 50458 477 30 generally generally RB 50458 477 31 exceeds exceed VBZ 50458 477 32 twenty twenty CD 50458 477 33 - - HYPH 50458 477 34 four four CD 50458 477 35 hours hour NNS 50458 477 36 . . . 50458 478 1 [ [ -LRB- 50458 478 2 52 52 CD 50458 478 3 ] ] -RRB- 50458 478 4 WARDEN WARDEN NNS 50458 478 5 and and CC 50458 478 6 WADDELL waddell NN 50458 478 7 : : : 50458 478 8 _ _ NNP 50458 478 9 Non non JJ 50458 478 10 - - JJ 50458 478 11 bacillar bacillar JJ 50458 478 12 Nature nature NN 50458 478 13 of of IN 50458 478 14 Abrus Abrus NNP 50458 478 15 Poison Poison NNP 50458 478 16 _ _ NNP 50458 478 17 . . . 50458 479 1 Calcutta Calcutta NNP 50458 479 2 , , , 50458 479 3 1884 1884 CD 50458 479 4 . . . 50458 480 1 [ [ -LRB- 50458 480 2 53 53 CD 50458 480 3 ] ] -RRB- 50458 480 4 KOBERT KOBERT NNP 50458 480 5 : : : 50458 480 6 _ _ NNP 50458 480 7 Arbeit Arbeit NNP 50458 480 8 . . . 50458 481 1 aus aus NNP 50458 481 2 dem dem NNP 50458 481 3 Pharmak Pharmak NNP 50458 481 4 . . . 50458 482 1 Institut Institut NNP 50458 482 2 . . . 50458 482 3 _ _ NNP 50458 482 4 Dorpat Dorpat NNP 50458 482 5 , , , 50458 482 6 1893 1893 CD 50458 482 7 . . . 50458 483 1 [ [ -LRB- 50458 483 2 54 54 CD 50458 483 3 ] ] -RRB- 50458 483 4 HELLIN HELLIN NNP 50458 483 5 : : : 50458 483 6 _ _ NNP 50458 483 7 Inaug Inaug NNP 50458 483 8 . . . 50458 484 1 Dissert Dissert NNP 50458 484 2 . . . 50458 484 3 _ _ NNP 50458 484 4 Dorpat Dorpat NNP 50458 484 5 , , , 50458 484 6 1891 1891 CD 50458 484 7 . . . 50458 485 1 [ [ -LRB- 50458 485 2 55 55 CD 50458 485 3 ] ] -RRB- 50458 485 4 EHRLICH ehrlich NN 50458 485 5 : : : 50458 485 6 Experiment experiment NN 50458 485 7 . . . 50458 486 1 Untersuchungen Untersuchungen NNP 50458 486 2 über über NN 50458 486 3 Immunität Immunität NNP 50458 486 4 . . . 50458 487 1 _ _ NNP 50458 487 2 Deutsch Deutsch NNP 50458 487 3 . . . 50458 488 1 Med Med NNP 50458 488 2 . . . 50458 489 1 Woch Woch NNP 50458 489 2 . . . 50458 489 3 _ _ NNP 50458 489 4 , , , 50458 489 5 1891 1891 CD 50458 489 6 . . . 50458 490 1 It -PRON- PRP 50458 490 2 is be VBZ 50458 490 3 possible possible JJ 50458 490 4 to to TO 50458 490 5 vaccinate vaccinate VB 50458 490 6 an an DT 50458 490 7 organism organism NN 50458 490 8 so so IN 50458 490 9 as as IN 50458 490 10 to to TO 50458 490 11 withstand withstand VB 50458 490 12 a a DT 50458 490 13 lethal lethal JJ 50458 490 14 dose dose NN 50458 490 15 of of IN 50458 490 16 abrin abrin NN 50458 490 17 , , , 50458 490 18 but but CC 50458 490 19 it -PRON- PRP 50458 490 20 requires require VBZ 50458 490 21 quite quite PDT 50458 490 22 a a DT 50458 490 23 long long JJ 50458 490 24 time time NN 50458 490 25 ; ; : 50458 490 26 it -PRON- PRP 50458 490 27 is be VBZ 50458 490 28 effected effect VBN 50458 490 29 by by IN 50458 490 30 injecting inject VBG 50458 490 31 into into IN 50458 490 32 a a DT 50458 490 33 suitable suitable JJ 50458 490 34 animal animal NN 50458 490 35 very very RB 50458 490 36 small small JJ 50458 490 37 doses dose NNS 50458 490 38 of of IN 50458 490 39 the the DT 50458 490 40 substance substance NN 50458 490 41 , , , 50458 490 42 and and CC 50458 490 43 increasing increase VBG 50458 490 44 the the DT 50458 490 45 quantity quantity NN 50458 490 46 gradually gradually RB 50458 490 47 . . . 50458 491 1 Rabbits rabbit NNS 50458 491 2 which which WDT 50458 491 3 have have VBP 50458 491 4 been be VBN 50458 491 5 rendered render VBN 50458 491 6 highly highly RB 50458 491 7 immune immune JJ 50458 491 8 towards towards IN 50458 491 9 venoms venom NNS 50458 491 10 are be VBP 50458 491 11 capable capable JJ 50458 491 12 of of IN 50458 491 13 resisting resist VBG 50458 491 14 without without IN 50458 491 15 inconvenience inconvenience NN 50458 491 16 doses dose NNS 50458 491 17 of of IN 50458 491 18 abrin abrin NN 50458 491 19 which which WDT 50458 491 20 are be VBP 50458 491 21 ordinarily ordinarily RB 50458 491 22 fatal fatal JJ 50458 491 23 ; ; : 50458 491 24 and and CC 50458 491 25 the the DT 50458 491 26 blood blood NN 50458 491 27 serum serum NN 50458 491 28 afforded afford VBN 50458 491 29 by by IN 50458 491 30 them -PRON- PRP 50458 491 31 contains contain VBZ 50458 491 32 a a DT 50458 491 33 specific specific JJ 50458 491 34 antibody antibody NN 50458 491 35 for for IN 50458 491 36 the the DT 50458 491 37 substance substance NN 50458 491 38 . . . 50458 492 1 = = NFP 50458 492 2 Ricin.=--This Ricin.=--This NNP 50458 492 3 vegetable vegetable NN 50458 492 4 toxalbumin toxalbumin NN 50458 492 5 has have VBZ 50458 492 6 been be VBN 50458 492 7 studied study VBN 50458 492 8 particularly particularly RB 50458 492 9 by by IN 50458 492 10 Stillmark,[56 stillmark,[56 NN 50458 492 11 ] ] -RRB- 50458 492 12 by by IN 50458 492 13 Dixon,[57 Dixon,[57 NNP 50458 492 14 ] ] -RRB- 50458 492 15 and and CC 50458 492 16 Thuson Thuson NNP 50458 492 17 . . . 50458 493 1 [ [ -LRB- 50458 493 2 58 58 CD 50458 493 3 ] ] -RRB- 50458 493 4 It -PRON- PRP 50458 493 5 is be VBZ 50458 493 6 found find VBN 50458 493 7 in in IN 50458 493 8 the the DT 50458 493 9 seeds seed NNS 50458 493 10 of of IN 50458 493 11 the the DT 50458 493 12 castor castor NN 50458 493 13 plant plant NN 50458 493 14 ; ; : 50458 493 15 three three CD 50458 493 16 or or CC 50458 493 17 four four CD 50458 493 18 of of IN 50458 493 19 the the DT 50458 493 20 seeds seed NNS 50458 493 21 suffice suffice VBP 50458 493 22 to to TO 50458 493 23 cause cause VB 50458 493 24 a a DT 50458 493 25 gastroenteritis gastroenteritis NN 50458 493 26 accompanied accompany VBN 50458 493 27 by by IN 50458 493 28 serious serious JJ 50458 493 29 symptoms symptom NNS 50458 493 30 and and CC 50458 493 31 even even RB 50458 493 32 by by IN 50458 493 33 death death NN 50458 493 34 . . . 50458 494 1 [ [ -LRB- 50458 494 2 56 56 CD 50458 494 3 ] ] -RRB- 50458 494 4 STILLMARK STILLMARK NNP 50458 494 5 : : : 50458 494 6 _ _ NNP 50458 494 7 Arbeit Arbeit NNP 50458 494 8 . . . 50458 495 1 aus aus NNP 50458 495 2 dem dem NNP 50458 495 3 pharmacol pharmacol NNP 50458 495 4 . . . 50458 496 1 Inst inst RB 50458 496 2 . . . 50458 497 1 Dorpat Dorpat NNP 50458 497 2 _ _ NNP 50458 497 3 , , , 50458 497 4 1889 1889 CD 50458 497 5 . . . 50458 498 1 [ [ -LRB- 50458 498 2 57 57 CD 50458 498 3 ] ] -RRB- 50458 498 4 DIXON DIXON NNP 50458 498 5 : : : 50458 498 6 _ _ NNP 50458 498 7 Austr Austr NNP 50458 498 8 . . . 50458 499 1 Med Med NNP 50458 499 2 . . . 50458 500 1 Gazette Gazette NNP 50458 500 2 _ _ NNP 50458 500 3 , , , 50458 500 4 1887 1887 CD 50458 500 5 . . . 50458 501 1 [ [ -LRB- 50458 501 2 58 58 CD 50458 501 3 ] ] -RRB- 50458 501 4 THUSON THUSON NNP 50458 501 5 : : : 50458 501 6 _ _ NNP 50458 501 7 Journ Journ NNP 50458 501 8 . . . 50458 502 1 f. f. NNP 50458 502 2 prakt prakt NNP 50458 502 3 . . . 50458 503 1 Chem Chem NNP 50458 503 2 . . . 50458 503 3 _ _ NNP 50458 503 4 , , , 50458 503 5 XCIV XCIV NNP 50458 503 6 , , , 50458 503 7 p. p. NN 50458 503 8 444 444 CD 50458 503 9 . . . 50458 504 1 It -PRON- PRP 50458 504 2 was be VBD 50458 504 3 first first RB 50458 504 4 isolated isolate VBN 50458 504 5 by by IN 50458 504 6 P. P. NNP 50458 504 7 Ehrlich Ehrlich NNP 50458 504 8 , , , 50458 504 9 by by IN 50458 504 10 treating treat VBG 50458 504 11 the the DT 50458 504 12 seeds seed NNS 50458 504 13 with with IN 50458 504 14 lukewarm lukewarm JJ 50458 504 15 water water NN 50458 504 16 , , , 50458 504 17 and and CC 50458 504 18 precipitating precipitate VBG 50458 504 19 the the DT 50458 504 20 aqueous aqueous JJ 50458 504 21 solution solution NN 50458 504 22 with with IN 50458 504 23 alcohol alcohol NN 50458 504 24 . . . 50458 505 1 The the DT 50458 505 2 toxalbumin toxalbumin NN 50458 505 3 is be VBZ 50458 505 4 soluble soluble JJ 50458 505 5 in in IN 50458 505 6 water water NN 50458 505 7 , , , 50458 505 8 but but CC 50458 505 9 on on IN 50458 505 10 boiling boil VBG 50458 505 11 the the DT 50458 505 12 solution solution NN 50458 505 13 , , , 50458 505 14 the the DT 50458 505 15 substance substance NN 50458 505 16 loses lose VBZ 50458 505 17 in in IN 50458 505 18 great great JJ 50458 505 19 measure measure NN 50458 505 20 its -PRON- PRP$ 50458 505 21 activity activity NN 50458 505 22 . . . 50458 506 1 Ricin Ricin NNS 50458 506 2 possesses possess VBZ 50458 506 3 considerable considerable JJ 50458 506 4 activity activity NN 50458 506 5 . . . 50458 507 1 0.00003 0.00003 CD 50458 507 2 Gm Gm NNP 50458 507 3 . . . 50458 508 1 suffice suffice VB 50458 508 2 to to TO 50458 508 3 kill kill VB 50458 508 4 a a DT 50458 508 5 rabbit rabbit NN 50458 508 6 when when WRB 50458 508 7 injected inject VBN 50458 508 8 hypodermically hypodermically RB 50458 508 9 ; ; : 50458 508 10 0.2 0.2 CD 50458 508 11 Gm Gm NNP 50458 508 12 . . . 50458 509 1 are be VBP 50458 509 2 fatal fatal JJ 50458 509 3 to to TO 50458 509 4 man man VB 50458 509 5 . . . 50458 510 1 The the DT 50458 510 2 action action NN 50458 510 3 is be VBZ 50458 510 4 not not RB 50458 510 5 immediate immediate JJ 50458 510 6 , , , 50458 510 7 but but CC 50458 510 8 follows follow VBZ 50458 510 9 a a DT 50458 510 10 period period NN 50458 510 11 of of IN 50458 510 12 incubation incubation NN 50458 510 13 . . . 50458 511 1 Ehrlich Ehrlich NNP 50458 511 2 has have VBZ 50458 511 3 shown show VBN 50458 511 4 that that IN 50458 511 5 , , , 50458 511 6 exercising exercise VBG 50458 511 7 precaution precaution NN 50458 511 8 , , , 50458 511 9 it -PRON- PRP 50458 511 10 is be VBZ 50458 511 11 possible possible JJ 50458 511 12 to to TO 50458 511 13 create create VB 50458 511 14 , , , 50458 511 15 as as IN 50458 511 16 with with IN 50458 511 17 abrin abrin NNP 50458 511 18 , , , 50458 511 19 a a DT 50458 511 20 condition condition NN 50458 511 21 of of IN 50458 511 22 tolerance tolerance NN 50458 511 23 or or CC 50458 511 24 habituation habituation NN 50458 511 25 , , , 50458 511 26 and and CC 50458 511 27 in in IN 50458 511 28 consequence consequence NN 50458 511 29 to to TO 50458 511 30 cause cause VB 50458 511 31 the the DT 50458 511 32 formation formation NN 50458 511 33 of of IN 50458 511 34 a a DT 50458 511 35 specific specific JJ 50458 511 36 antibody antibody NN 50458 511 37 . . . 50458 512 1 = = NFP 50458 512 2 Robin.=--This Robin.=--This NNP 50458 512 3 toxic toxic JJ 50458 512 4 albuminoid albuminoid NN 50458 512 5 was be VBD 50458 512 6 obtained obtain VBN 50458 512 7 from from IN 50458 512 8 the the DT 50458 512 9 bark bark NN 50458 512 10 of of IN 50458 512 11 an an DT 50458 512 12 Acacia Acacia NNP 50458 512 13 ( ( -LRB- 50458 512 14 Robinia Robinia NNP 50458 512 15 Pseudacacia Pseudacacia NNP 50458 512 16 ) ) -RRB- 50458 512 17 by by IN 50458 512 18 Power Power NNP 50458 512 19 and and CC 50458 512 20 Cambier,[59 Cambier,[59 NNP 50458 512 21 ] ] -RRB- 50458 512 22 by by IN 50458 512 23 exhausting exhaust VBG 50458 512 24 with with IN 50458 512 25 water water NN 50458 512 26 at at IN 50458 512 27 a a DT 50458 512 28 temperature temperature NN 50458 512 29 of of IN 50458 512 30 about about RB 50458 512 31 30 30 CD 50458 512 32 ° ° , 50458 512 33 C. C. NNP 50458 512 34 , , , 50458 512 35 and and CC 50458 512 36 precipitating precipitate VBG 50458 512 37 the the DT 50458 512 38 infusion infusion NN 50458 512 39 with with IN 50458 512 40 alcohol alcohol NN 50458 512 41 . . . 50458 513 1 The the DT 50458 513 2 substance substance NN 50458 513 3 is be VBZ 50458 513 4 analogous analogous JJ 50458 513 5 to to IN 50458 513 6 ricin ricin NNS 50458 513 7 , , , 50458 513 8 and and CC 50458 513 9 like like IN 50458 513 10 this this DT 50458 513 11 , , , 50458 513 12 possesses possess VBZ 50458 513 13 powerful powerful JJ 50458 513 14 toxic toxic JJ 50458 513 15 properties property NNS 50458 513 16 . . . 50458 514 1 [ [ -LRB- 50458 514 2 59 59 CD 50458 514 3 ] ] -RRB- 50458 514 4 POWER POWER NNS 50458 514 5 and and CC 50458 514 6 CAMBIER CAMBIER NNP 50458 514 7 : : : 50458 514 8 _ _ NNP 50458 514 9 Pharm Pharm NNP 50458 514 10 . . . 50458 515 1 Journ Journ NNP 50458 515 2 . . . 50458 516 1 and and CC 50458 516 2 Transact Transact NNP 50458 516 3 . . . 50458 516 4 _ _ NNP 50458 516 5 , , , 50458 516 6 1890 1890 CD 50458 516 7 . . . 50458 517 1 = = NFP 50458 517 2 Toxicity toxicity NN 50458 517 3 of of IN 50458 517 4 the the DT 50458 517 5 Vegetable Vegetable NNP 50458 517 6 Diastases.=--The Diastases.=--The NNP 50458 517 7 diastases diastasis NNS 50458 517 8 , , , 50458 517 9 which which WDT 50458 517 10 have have VBP 50458 517 11 been be VBN 50458 517 12 treated treat VBN 50458 517 13 of of IN 50458 517 14 in in IN 50458 517 15 a a DT 50458 517 16 volume volume NN 50458 517 17 of of IN 50458 517 18 the the DT 50458 517 19 Encyclopédie Encyclopédie NNP 50458 517 20 Léauté,[60 Léauté,[60 NNP 50458 517 21 ] ] -RRB- 50458 517 22 and and CC 50458 517 23 to to TO 50458 517 24 which which WDT 50458 517 25 we -PRON- PRP 50458 517 26 would would MD 50458 517 27 refer refer VB 50458 517 28 the the DT 50458 517 29 reader reader NN 50458 517 30 who who WP 50458 517 31 is be VBZ 50458 517 32 desirous desirous JJ 50458 517 33 of of IN 50458 517 34 more more RBR 50458 517 35 complete complete JJ 50458 517 36 details detail NNS 50458 517 37 , , , 50458 517 38 develop develop VB 50458 517 39 powerfully powerfully RB 50458 517 40 energetic energetic JJ 50458 517 41 toxic toxic JJ 50458 517 42 properties property NNS 50458 517 43 when when WRB 50458 517 44 injected inject VBN 50458 517 45 into into IN 50458 517 46 the the DT 50458 517 47 organism organism NN 50458 517 48 . . . 50458 518 1 Thus thus RB 50458 518 2 _ _ NNP 50458 518 3 amylase amylase JJ 50458 518 4 _ _ NNP 50458 518 5 causes cause VBZ 50458 518 6 , , , 50458 518 7 when when WRB 50458 518 8 injected inject VBN 50458 518 9 subcutaneously subcutaneously RB 50458 518 10 , , , 50458 518 11 a a DT 50458 518 12 considerable considerable JJ 50458 518 13 rise rise NN 50458 518 14 of of IN 50458 518 15 temperature temperature NN 50458 518 16 , , , 50458 518 17 but but CC 50458 518 18 without without IN 50458 518 19 any any DT 50458 518 20 other other JJ 50458 518 21 toxic toxic JJ 50458 518 22 symptoms symptom NNS 50458 518 23 . . . 50458 519 1 _ _ NNP 50458 519 2 Invertin Invertin NNP 50458 519 3 _ _ NNP 50458 519 4 or or CC 50458 519 5 _ _ NNP 50458 519 6 sucrase sucrase NN 50458 519 7 _ _ NNP 50458 519 8 was be VBD 50458 519 9 studied study VBN 50458 519 10 by by IN 50458 519 11 Roussy Roussy NNP 50458 519 12 under under IN 50458 519 13 the the DT 50458 519 14 name name NN 50458 519 15 _ _ NNP 50458 519 16 pyretogenin pyretogenin NNP 50458 519 17 _ _ NNP 50458 519 18 , , , 50458 519 19 but but CC 50458 519 20 it -PRON- PRP 50458 519 21 appears appear VBZ 50458 519 22 probable probable JJ 50458 519 23 that that IN 50458 519 24 this this DT 50458 519 25 diastase diastase NN 50458 519 26 was be VBD 50458 519 27 not not RB 50458 519 28 the the DT 50458 519 29 only only JJ 50458 519 30 substance substance NN 50458 519 31 present present JJ 50458 519 32 in in IN 50458 519 33 the the DT 50458 519 34 product product NN 50458 519 35 , , , 50458 519 36 but but CC 50458 519 37 that that IN 50458 519 38 there there EX 50458 519 39 were be VBD 50458 519 40 present present JJ 50458 519 41 reducing reduce VBG 50458 519 42 diastases diastasis NNS 50458 519 43 , , , 50458 519 44 as as IN 50458 519 45 we -PRON- PRP 50458 519 46 have have VBP 50458 519 47 already already RB 50458 519 48 shown show VBN 50458 519 49 in in IN 50458 519 50 the the DT 50458 519 51 first first JJ 50458 519 52 volume volume NN 50458 519 53 of of IN 50458 519 54 this this DT 50458 519 55 collection collection NN 50458 519 56 , , , 50458 519 57 devoted devote VBN 50458 519 58 to to IN 50458 519 59 the the DT 50458 519 60 phenomena phenomenon NNS 50458 519 61 of of IN 50458 519 62 reduction reduction NN 50458 519 63 within within IN 50458 519 64 the the DT 50458 519 65 living live VBG 50458 519 66 organism organism NN 50458 519 67 . . . 50458 520 1 [ [ -LRB- 50458 520 2 60 60 CD 50458 520 3 ] ] -RRB- 50458 520 4 POZZI POZZI NNP 50458 520 5 - - HYPH 50458 520 6 ESCOT ESCOT NNP 50458 520 7 : : : 50458 520 8 _ _ NNP 50458 520 9 Les Les NNP 50458 520 10 Diastases Diastases NNP 50458 520 11 et et NNP 50458 520 12 leurs leur VBZ 50458 520 13 Applications Applications NNPS 50458 520 14 _ _ NNP 50458 520 15 , , , 50458 520 16 Masson Masson NNP 50458 520 17 , , , 50458 520 18 1900 1900 CD 50458 520 19 . . . 50458 521 1 The the DT 50458 521 2 pyretogenin pyretogenin NN 50458 521 3 of of IN 50458 521 4 Roussy Roussy NNP 50458 521 5 gives give VBZ 50458 521 6 rise rise NN 50458 521 7 to to IN 50458 521 8 an an DT 50458 521 9 attack attack NN 50458 521 10 of of IN 50458 521 11 violent violent JJ 50458 521 12 fever fever NN 50458 521 13 , , , 50458 521 14 but but CC 50458 521 15 it -PRON- PRP 50458 521 16 loses lose VBZ 50458 521 17 all all DT 50458 521 18 activity activity NN 50458 521 19 when when WRB 50458 521 20 heated heat VBN 50458 521 21 to to IN 50458 521 22 80 80 CD 50458 521 23 - - SYM 50458 521 24 100 100 CD 50458 521 25 ° ° , 50458 521 26 C. C. NNP 50458 521 27 Through through IN 50458 521 28 his -PRON- PRP$ 50458 521 29 researches research NNS 50458 521 30 , , , 50458 521 31 Roussy Roussy NNP 50458 521 32 clearly clearly RB 50458 521 33 demonstrated,[61 demonstrated,[61 NN 50458 521 34 ] ] -RRB- 50458 521 35 for for IN 50458 521 36 the the DT 50458 521 37 first first JJ 50458 521 38 time time NN 50458 521 39 , , , 50458 521 40 that that IN 50458 521 41 the the DT 50458 521 42 fever fever NN 50458 521 43 may may MD 50458 521 44 cause cause VB 50458 521 45 the the DT 50458 521 46 formation formation NN 50458 521 47 within within IN 50458 521 48 the the DT 50458 521 49 blood blood NN 50458 521 50 of of IN 50458 521 51 a a DT 50458 521 52 substance substance NN 50458 521 53 clearly clearly RB 50458 521 54 belonging belong VBG 50458 521 55 to to IN 50458 521 56 the the DT 50458 521 57 class class NN 50458 521 58 of of IN 50458 521 59 soluble soluble JJ 50458 521 60 ferments ferment NNS 50458 521 61 or or CC 50458 521 62 zymases zymase NNS 50458 521 63 . . . 50458 522 1 Now now RB 50458 522 2 , , , 50458 522 3 it -PRON- PRP 50458 522 4 is be VBZ 50458 522 5 well well RB 50458 522 6 known know VBN 50458 522 7 that that IN 50458 522 8 within within IN 50458 522 9 the the DT 50458 522 10 animal animal NN 50458 522 11 economy economy NN 50458 522 12 there there RB 50458 522 13 exist exist VBP 50458 522 14 many many JJ 50458 522 15 ferments ferment NNS 50458 522 16 of of IN 50458 522 17 this this DT 50458 522 18 character character NN 50458 522 19 ; ; , 50458 522 20 and and CC 50458 522 21 experiment experiment NN 50458 522 22 has have VBZ 50458 522 23 shown show VBN 50458 522 24 that that IN 50458 522 25 they -PRON- PRP 50458 522 26 can can MD 50458 522 27 , , , 50458 522 28 at at IN 50458 522 29 a a DT 50458 522 30 given give VBN 50458 522 31 period period NN 50458 522 32 and and CC 50458 522 33 under under IN 50458 522 34 various various JJ 50458 522 35 influences influence NNS 50458 522 36 , , , 50458 522 37 leave leave VB 50458 522 38 the the DT 50458 522 39 cells cell NNS 50458 522 40 in in IN 50458 522 41 which which WDT 50458 522 42 they -PRON- PRP 50458 522 43 are be VBP 50458 522 44 normally normally RB 50458 522 45 localized localize VBN 50458 522 46 , , , 50458 522 47 pass pass VB 50458 522 48 into into IN 50458 522 49 the the DT 50458 522 50 blood blood NN 50458 522 51 plasma plasma NN 50458 522 52 , , , 50458 522 53 and and CC 50458 522 54 reach reach VB 50458 522 55 the the DT 50458 522 56 nervous nervous JJ 50458 522 57 centers center NNS 50458 522 58 , , , 50458 522 59 where where WRB 50458 522 60 they -PRON- PRP 50458 522 61 cause cause VBP 50458 522 62 serious serious JJ 50458 522 63 effects effect NNS 50458 522 64 . . . 50458 523 1 We -PRON- PRP 50458 523 2 have have VBP 50458 523 3 already already RB 50458 523 4 dwelt dwell VBN 50458 523 5 upon upon IN 50458 523 6 the the DT 50458 523 7 mechanism mechanism NN 50458 523 8 of of IN 50458 523 9 autointoxication autointoxication NN 50458 523 10 of of IN 50458 523 11 the the DT 50458 523 12 organism organism NN 50458 523 13 . . . 50458 524 1 The the DT 50458 524 2 toxic toxic JJ 50458 524 3 action action NN 50458 524 4 of of IN 50458 524 5 certain certain JJ 50458 524 6 digestive digestive JJ 50458 524 7 diastases diastasis NNS 50458 524 8 has have VBZ 50458 524 9 been be VBN 50458 524 10 shown show VBN 50458 524 11 by by IN 50458 524 12 Hildebrandt Hildebrandt NNP 50458 524 13 , , , 50458 524 14 who who WP 50458 524 15 has have VBZ 50458 524 16 demonstrated demonstrate VBN 50458 524 17 that that IN 50458 524 18 0.1 0.1 CD 50458 524 19 Gm Gm NNP 50458 524 20 . . . 50458 525 1 of of IN 50458 525 2 pepsin pepsin NNP 50458 525 3 is be VBZ 50458 525 4 capable capable JJ 50458 525 5 of of IN 50458 525 6 killing kill VBG 50458 525 7 a a DT 50458 525 8 rabbit rabbit NN 50458 525 9 in in IN 50458 525 10 two two CD 50458 525 11 or or CC 50458 525 12 three three CD 50458 525 13 days day NNS 50458 525 14 . . . 50458 526 1 [ [ -LRB- 50458 526 2 61 61 CD 50458 526 3 ] ] -RRB- 50458 526 4 ROUSSY ROUSSY NNP 50458 526 5 : : : 50458 526 6 _ _ NNP 50458 526 7 Aperçu Aperçu NNP 50458 526 8 historique historique NNP 50458 526 9 sur sur NNP 50458 526 10 les les NNP 50458 526 11 ferments ferment NNS 50458 526 12 et et NNP 50458 526 13 fermentations fermentation NNS 50458 526 14 _ _ NNP 50458 526 15 . . . 50458 527 1 Paris Paris NNP 50458 527 2 , , , 50458 527 3 1901 1901 CD 50458 527 4 . . . 50458 528 1 J. J. NNP 50458 528 2 Rousset Rousset NNP 50458 528 3 , , , 50458 528 4 publ publ NNS 50458 528 5 . . . 50458 529 1 II ii CD 50458 529 2 . . . 50458 530 1 TOXINS toxin NNS 50458 530 2 FROM from IN 50458 530 3 MUSHROOMS MUSHROOMS NNP 50458 530 4 . . . 50458 531 1 Mushrooms mushroom NNS 50458 531 2 are be VBP 50458 531 3 alimentary alimentary JJ 50458 531 4 substances substance NNS 50458 531 5 of of IN 50458 531 6 the the DT 50458 531 7 highest high JJS 50458 531 8 order order NN 50458 531 9 , , , 50458 531 10 causing cause VBG 50458 531 11 a a DT 50458 531 12 general general JJ 50458 531 13 stimulation stimulation NN 50458 531 14 of of IN 50458 531 15 the the DT 50458 531 16 entire entire JJ 50458 531 17 organism organism NN 50458 531 18 . . . 50458 532 1 The the DT 50458 532 2 substances substance NNS 50458 532 3 met meet VBD 50458 532 4 with with IN 50458 532 5 belong belong NN 50458 532 6 , , , 50458 532 7 according accord VBG 50458 532 8 to to IN 50458 532 9 their -PRON- PRP$ 50458 532 10 composition composition NN 50458 532 11 , , , 50458 532 12 to to IN 50458 532 13 different different JJ 50458 532 14 classes class NNS 50458 532 15 -- -- : 50458 532 16 celluloses cellulose NNS 50458 532 17 , , , 50458 532 18 sugars sugar NNS 50458 532 19 , , , 50458 532 20 and and CC 50458 532 21 amylaceous amylaceous JJ 50458 532 22 substances substance NNS 50458 532 23 , , , 50458 532 24 alcohols alcohol NNS 50458 532 25 , , , 50458 532 26 acids acid NNS 50458 532 27 , , , 50458 532 28 fats fat NNS 50458 532 29 , , , 50458 532 30 astringents astringent NNS 50458 532 31 , , , 50458 532 32 essential essential JJ 50458 532 33 oils oil NNS 50458 532 34 , , , 50458 532 35 resins resin NNS 50458 532 36 , , , 50458 532 37 alkaloids alkaloid NNS 50458 532 38 , , , 50458 532 39 and and CC 50458 532 40 albuminoids albuminoid NNS 50458 532 41 . . . 50458 533 1 The the DT 50458 533 2 study study NN 50458 533 3 of of IN 50458 533 4 the the DT 50458 533 5 last last JJ 50458 533 6 only only RB 50458 533 7 , , , 50458 533 8 the the DT 50458 533 9 albuminoids albuminoid NNS 50458 533 10 and and CC 50458 533 11 diastases diastasis NNS 50458 533 12 , , , 50458 533 13 interests interest NNS 50458 533 14 us -PRON- PRP 50458 533 15 here here RB 50458 533 16 . . . 50458 534 1 The the DT 50458 534 2 most most RBS 50458 534 3 important important JJ 50458 534 4 of of IN 50458 534 5 these these DT 50458 534 6 albuminoid albuminoid NN 50458 534 7 substances substance NNS 50458 534 8 , , , 50458 534 9 _ _ NNP 50458 534 10 phallin phallin NNP 50458 534 11 _ _ NNP 50458 534 12 , , , 50458 534 13 was be VBD 50458 534 14 discovered discover VBN 50458 534 15 in in IN 50458 534 16 1890 1890 CD 50458 534 17 by by IN 50458 534 18 Kobert Kobert NNP 50458 534 19 . . . 50458 535 1 Pouchet Pouchet NNP 50458 535 2 also also RB 50458 535 3 has have VBZ 50458 535 4 isolated isolate VBN 50458 535 5 a a DT 50458 535 6 whole whole JJ 50458 535 7 series series NN 50458 535 8 of of IN 50458 535 9 other other JJ 50458 535 10 toxic toxic JJ 50458 535 11 albuminoids albuminoid NNS 50458 535 12 , , , 50458 535 13 particularly particularly RB 50458 535 14 from from IN 50458 535 15 Amanita Amanita NNP 50458 535 16 muscaria muscaria NN 50458 535 17 ( ( -LRB- 50458 535 18 Fly Fly NNP 50458 535 19 Agaric Agaric NNP 50458 535 20 ) ) -RRB- 50458 535 21 . . . 50458 536 1 There there EX 50458 536 2 are be VBP 50458 536 3 alimentary alimentary JJ 50458 536 4 as as RB 50458 536 5 well well RB 50458 536 6 as as IN 50458 536 7 toxic toxic JJ 50458 536 8 species specie NNS 50458 536 9 in in IN 50458 536 10 every every DT 50458 536 11 possible possible JJ 50458 536 12 variety variety NN 50458 536 13 among among IN 50458 536 14 mushrooms mushroom NNS 50458 536 15 , , , 50458 536 16 some some DT 50458 536 17 species specie NNS 50458 536 18 consisting consist VBG 50458 536 19 chiefly chiefly RB 50458 536 20 of of IN 50458 536 21 the the DT 50458 536 22 edible edible JJ 50458 536 23 kind kind NN 50458 536 24 , , , 50458 536 25 others other NNS 50458 536 26 consisting consist VBG 50458 536 27 of of IN 50458 536 28 the the DT 50458 536 29 poisonous poisonous JJ 50458 536 30 variety variety NN 50458 536 31 . . . 50458 537 1 In in IN 50458 537 2 consequence consequence NN 50458 537 3 of of IN 50458 537 4 the the DT 50458 537 5 toxicity toxicity NN 50458 537 6 of of IN 50458 537 7 mushrooms mushroom NNS 50458 537 8 , , , 50458 537 9 great great JJ 50458 537 10 attention attention NN 50458 537 11 must must MD 50458 537 12 be be VB 50458 537 13 given give VBN 50458 537 14 to to IN 50458 537 15 the the DT 50458 537 16 treatment treatment NN 50458 537 17 to to TO 50458 537 18 which which WDT 50458 537 19 they -PRON- PRP 50458 537 20 are be VBP 50458 537 21 subjected subject VBN 50458 537 22 when when WRB 50458 537 23 it -PRON- PRP 50458 537 24 is be VBZ 50458 537 25 desired desire VBN 50458 537 26 to to TO 50458 537 27 utilize utilize VB 50458 537 28 them -PRON- PRP 50458 537 29 for for IN 50458 537 30 alimentary alimentary JJ 50458 537 31 purposes purpose NNS 50458 537 32 . . . 50458 538 1 Thus thus RB 50458 538 2 the the DT 50458 538 3 toxic toxic JJ 50458 538 4 principles principle NNS 50458 538 5 of of IN 50458 538 6 several several JJ 50458 538 7 varieties variety NNS 50458 538 8 can can MD 50458 538 9 be be VB 50458 538 10 removed remove VBN 50458 538 11 , , , 50458 538 12 and and CC 50458 538 13 the the DT 50458 538 14 mushrooms mushroom NNS 50458 538 15 rendered render VBN 50458 538 16 edible edible JJ 50458 538 17 by by IN 50458 538 18 very very RB 50458 538 19 simple simple JJ 50458 538 20 means mean NNS 50458 538 21 . . . 50458 539 1 Pouchet Pouchet NNP 50458 539 2 has have VBZ 50458 539 3 made make VBN 50458 539 4 a a DT 50458 539 5 very very RB 50458 539 6 ingenious ingenious JJ 50458 539 7 comparison comparison NN 50458 539 8 between between IN 50458 539 9 the the DT 50458 539 10 ethereal ethereal NN 50458 539 11 , , , 50458 539 12 alcoholic alcoholic JJ 50458 539 13 , , , 50458 539 14 saline saline JJ 50458 539 15 , , , 50458 539 16 and and CC 50458 539 17 aqueous aqueous JJ 50458 539 18 extracts extract NNS 50458 539 19 of of IN 50458 539 20 mushrooms mushroom NNS 50458 539 21 , , , 50458 539 22 and and CC 50458 539 23 bacterial bacterial JJ 50458 539 24 cultures culture NNS 50458 539 25 . . . 50458 540 1 The the DT 50458 540 2 analogy analogy NN 50458 540 3 is be VBZ 50458 540 4 striking strike VBG 50458 540 5 as as IN 50458 540 6 to to IN 50458 540 7 the the DT 50458 540 8 presence presence NN 50458 540 9 of of IN 50458 540 10 toxin toxin NN 50458 540 11 , , , 50458 540 12 toxalbumose toxalbumose RB 50458 540 13 , , , 50458 540 14 and and CC 50458 540 15 albumoses albumose VBZ 50458 540 16 more more RBR 50458 540 17 or or CC 50458 540 18 less less RBR 50458 540 19 toxic toxic JJ 50458 540 20 ; ; : 50458 540 21 it -PRON- PRP 50458 540 22 is be VBZ 50458 540 23 moreover moreover RB 50458 540 24 not not RB 50458 540 25 exaggerated exaggerate VBN 50458 540 26 , , , 50458 540 27 since since IN 50458 540 28 , , , 50458 540 29 according accord VBG 50458 540 30 to to IN 50458 540 31 the the DT 50458 540 32 classification classification NN 50458 540 33 generally generally RB 50458 540 34 admitted admit VBN 50458 540 35 , , , 50458 540 36 mushrooms mushroom NNS 50458 540 37 are be VBP 50458 540 38 nothing nothing NN 50458 540 39 more more JJR 50458 540 40 than than IN 50458 540 41 the the DT 50458 540 42 very very RB 50458 540 43 advanced advanced JJ 50458 540 44 representatives representative NNS 50458 540 45 of of IN 50458 540 46 a a DT 50458 540 47 group group NN 50458 540 48 the the DT 50458 540 49 more more RBR 50458 540 50 simple simple JJ 50458 540 51 members member NNS 50458 540 52 of of IN 50458 540 53 which which WDT 50458 540 54 constitute constitute VBP 50458 540 55 the the DT 50458 540 56 bacteria bacteria NNS 50458 540 57 . . . 50458 541 1 The the DT 50458 541 2 same same JJ 50458 541 3 author author NN 50458 541 4 has have VBZ 50458 541 5 shown show VBN 50458 541 6 that that DT 50458 541 7 phallin phallin NN 50458 541 8 obtained obtain VBD 50458 541 9 from from IN 50458 541 10 the the DT 50458 541 11 juice juice NN 50458 541 12 of of IN 50458 541 13 the the DT 50458 541 14 Fly Fly NNP 50458 541 15 Agaric Agaric NNP 50458 541 16 will will MD 50458 541 17 kill kill VB 50458 541 18 a a DT 50458 541 19 guinea guinea NN 50458 541 20 - - HYPH 50458 541 21 pig pig NN 50458 541 22 weighing weigh VBG 50458 541 23 600 600 CD 50458 541 24 grammes gramme NNS 50458 541 25 in in IN 50458 541 26 one one CD 50458 541 27 hour hour NN 50458 541 28 . . . 50458 542 1 As as IN 50458 542 2 we -PRON- PRP 50458 542 3 have have VBP 50458 542 4 already already RB 50458 542 5 stated state VBN 50458 542 6 , , , 50458 542 7 it -PRON- PRP 50458 542 8 is be VBZ 50458 542 9 the the DT 50458 542 10 phalline phalline NN 50458 542 11 to to TO 50458 542 12 which which WDT 50458 542 13 the the DT 50458 542 14 ordinary ordinary JJ 50458 542 15 disorders disorder NNS 50458 542 16 which which WDT 50458 542 17 mushrooms mushroom NNS 50458 542 18 cause cause NN 50458 542 19 are be VBP 50458 542 20 due due JJ 50458 542 21 . . . 50458 543 1 According accord VBG 50458 543 2 to to IN 50458 543 3 Kobert Kobert NNP 50458 543 4 , , , 50458 543 5 a a DT 50458 543 6 1:250 1:250 CD 50458 543 7 000 000 CD 50458 543 8 solution solution NN 50458 543 9 of of IN 50458 543 10 this this DT 50458 543 11 substance substance NN 50458 543 12 causes cause VBZ 50458 543 13 an an DT 50458 543 14 intense intense JJ 50458 543 15 hemolysis hemolysis NN 50458 543 16 , , , 50458 543 17 with with IN 50458 543 18 all all DT 50458 543 19 its -PRON- PRP$ 50458 543 20 disastrous disastrous JJ 50458 543 21 consequences consequence NNS 50458 543 22 . . . 50458 544 1 According accord VBG 50458 544 2 to to IN 50458 544 3 Pouchet Pouchet NNP 50458 544 4 , , , 50458 544 5 the the DT 50458 544 6 flesh flesh NN 50458 544 7 of of IN 50458 544 8 mushrooms mushroom NNS 50458 544 9 must must MD 50458 544 10 be be VB 50458 544 11 compared compare VBN 50458 544 12 with with IN 50458 544 13 meat meat NN 50458 544 14 that that WDT 50458 544 15 has have VBZ 50458 544 16 been be VBN 50458 544 17 kept keep VBN 50458 544 18 for for IN 50458 544 19 some some DT 50458 544 20 time time NN 50458 544 21 to to TO 50458 544 22 become become VB 50458 544 23 tender tender JJ 50458 544 24 , , , 50458 544 25 and and CC 50458 544 26 it -PRON- PRP 50458 544 27 is be VBZ 50458 544 28 well well RB 50458 544 29 known know VBN 50458 544 30 that that IN 50458 544 31 though though IN 50458 544 32 this this DT 50458 544 33 " " `` 50458 544 34 tendering tendering JJ 50458 544 35 " " '' 50458 544 36 process process NN 50458 544 37 renders render VBZ 50458 544 38 the the DT 50458 544 39 meat meat NN 50458 544 40 more more RBR 50458 544 41 digestible digestible JJ 50458 544 42 , , , 50458 544 43 it -PRON- PRP 50458 544 44 may may MD 50458 544 45 also also RB 50458 544 46 allow allow VB 50458 544 47 the the DT 50458 544 48 meat meat NN 50458 544 49 to to TO 50458 544 50 acquire acquire VB 50458 544 51 noxious noxious JJ 50458 544 52 properties property NNS 50458 544 53 , , , 50458 544 54 due due IN 50458 544 55 to to IN 50458 544 56 the the DT 50458 544 57 presence presence NN 50458 544 58 of of IN 50458 544 59 toxins toxin NNS 50458 544 60 . . . 50458 545 1 Phallin Phallin NNP 50458 545 2 is be VBZ 50458 545 3 the the DT 50458 545 4 type type NN 50458 545 5 of of IN 50458 545 6 those those DT 50458 545 7 toxic toxic JJ 50458 545 8 albuminoids albuminoid NNS 50458 545 9 of of IN 50458 545 10 unknown unknown JJ 50458 545 11 composition composition NN 50458 545 12 which which WDT 50458 545 13 exist exist VBP 50458 545 14 in in IN 50458 545 15 mushrooms mushroom NNS 50458 545 16 , , , 50458 545 17 and and CC 50458 545 18 which which WDT 50458 545 19 are be VBP 50458 545 20 comprised comprise VBN 50458 545 21 under under IN 50458 545 22 the the DT 50458 545 23 name name NN 50458 545 24 _ _ NNP 50458 545 25 sapotoxins sapotoxins NNP 50458 545 26 _ _ NNP 50458 545 27 . . . 50458 546 1 The the DT 50458 546 2 intravenous intravenous JJ 50458 546 3 injection injection NN 50458 546 4 of of IN 50458 546 5 phallin phallin NNP 50458 546 6 into into IN 50458 546 7 an an DT 50458 546 8 animal animal NN 50458 546 9 , , , 50458 546 10 in in IN 50458 546 11 the the DT 50458 546 12 proportion proportion NN 50458 546 13 of of IN 50458 546 14 1 1 CD 50458 546 15 part part NN 50458 546 16 to to IN 50458 546 17 1 1 CD 50458 546 18 000 000 CD 50458 546 19 000 000 CD 50458 546 20 parts part NNS 50458 546 21 of of IN 50458 546 22 body body NN 50458 546 23 weight weight NN 50458 546 24 , , , 50458 546 25 causes cause VBZ 50458 546 26 sudden sudden JJ 50458 546 27 death death NN 50458 546 28 within within IN 50458 546 29 one one CD 50458 546 30 minute minute NN 50458 546 31 ; ; : 50458 546 32 in in IN 50458 546 33 the the DT 50458 546 34 proportion proportion NN 50458 546 35 of of IN 50458 546 36 1:5 1:5 CD 50458 546 37 000 000 CD 50458 546 38 000 000 CD 50458 546 39 , , , 50458 546 40 death death NN 50458 546 41 occurs occur VBZ 50458 546 42 in in RB 50458 546 43 about about RB 50458 546 44 three three CD 50458 546 45 minutes minute NNS 50458 546 46 ; ; : 50458 546 47 in in IN 50458 546 48 the the DT 50458 546 49 proportion proportion NN 50458 546 50 of of IN 50458 546 51 1:50 1:50 CD 50458 546 52 000 000 CD 50458 546 53 000 000 CD 50458 546 54 , , , 50458 546 55 death death NN 50458 546 56 also also RB 50458 546 57 occurs occur VBZ 50458 546 58 , , , 50458 546 59 but but CC 50458 546 60 is be VBZ 50458 546 61 greatly greatly RB 50458 546 62 retarded retarded JJ 50458 546 63 . . . 50458 547 1 An an DT 50458 547 2 injection injection NN 50458 547 3 of of IN 50458 547 4 0.0005 0.0005 NNP 50458 547 5 Gm Gm NNP 50458 547 6 . . . 50458 548 1 per per IN 50458 548 2 kilo kilo NNP 50458 548 3 of of IN 50458 548 4 body body NN 50458 548 5 weight weight NN 50458 548 6 of of IN 50458 548 7 animal animal NN 50458 548 8 causes cause VBZ 50458 548 9 solution solution NN 50458 548 10 of of IN 50458 548 11 the the DT 50458 548 12 blood blood NN 50458 548 13 corpuscles corpuscle NNS 50458 548 14 to to IN 50458 548 15 such such PDT 50458 548 16 an an DT 50458 548 17 extent extent NN 50458 548 18 that that IN 50458 548 19 thirty thirty CD 50458 548 20 minutes minute NNS 50458 548 21 later later RB 50458 548 22 the the DT 50458 548 23 blood blood NN 50458 548 24 serum serum NN 50458 548 25 is be VBZ 50458 548 26 strongly strongly RB 50458 548 27 colored color VBN 50458 548 28 red red JJ 50458 548 29 , , , 50458 548 30 as as RB 50458 548 31 well well RB 50458 548 32 as as IN 50458 548 33 the the DT 50458 548 34 veins vein NNS 50458 548 35 . . . 50458 549 1 Instead instead RB 50458 549 2 of of IN 50458 549 3 being be VBG 50458 549 4 easily easily RB 50458 549 5 altered alter VBN 50458 549 6 under under IN 50458 549 7 the the DT 50458 549 8 influence influence NN 50458 549 9 of of IN 50458 549 10 an an DT 50458 549 11 elevated elevated JJ 50458 549 12 temperature temperature NN 50458 549 13 , , , 50458 549 14 as as IN 50458 549 15 are be VBP 50458 549 16 many many JJ 50458 549 17 of of IN 50458 549 18 the the DT 50458 549 19 albuminoid albuminoid NN 50458 549 20 substances substance NNS 50458 549 21 , , , 50458 549 22 whereby whereby WRB 50458 549 23 their -PRON- PRP$ 50458 549 24 toxic toxic JJ 50458 549 25 power power NN 50458 549 26 is be VBZ 50458 549 27 lost lose VBN 50458 549 28 , , , 50458 549 29 phallin phallin NNP 50458 549 30 may may MD 50458 549 31 be be VB 50458 549 32 boiled boil VBN 50458 549 33 for for IN 50458 549 34 half half PDT 50458 549 35 an an DT 50458 549 36 hour hour NN 50458 549 37 with with IN 50458 549 38 water water NN 50458 549 39 without without IN 50458 549 40 undergoing undergo VBG 50458 549 41 any any DT 50458 549 42 noticeable noticeable JJ 50458 549 43 alteration alteration NN 50458 549 44 . . . 50458 550 1 Pellegrini Pellegrini NNP 50458 550 2 has have VBZ 50458 550 3 observed observe VBN 50458 550 4 that that IN 50458 550 5 the the DT 50458 550 6 dried dry VBN 50458 550 7 juice juice NN 50458 550 8 of of IN 50458 550 9 Amanita Amanita NNP 50458 550 10 Phalloides Phalloides NNP 50458 550 11 ( ( -LRB- 50458 550 12 Death death NN 50458 550 13 - - HYPH 50458 550 14 cup cup NNP 50458 550 15 ) ) -RRB- 50458 550 16 preserves preserve VBZ 50458 550 17 its -PRON- PRP$ 50458 550 18 properties property NNS 50458 550 19 for for IN 50458 550 20 more more JJR 50458 550 21 than than IN 50458 550 22 a a DT 50458 550 23 year year NN 50458 550 24 . . . 50458 551 1 According accord VBG 50458 551 2 to to IN 50458 551 3 a a DT 50458 551 4 recent recent JJ 50458 551 5 paper paper NN 50458 551 6 by by IN 50458 551 7 Gillot Gillot NNP 50458 551 8 , , , 50458 551 9 the the DT 50458 551 10 symptoms symptom NNS 50458 551 11 of of IN 50458 551 12 poisoning poisoning NN 50458 551 13 by by IN 50458 551 14 mushrooms mushroom NNS 50458 551 15 must must MD 50458 551 16 be be VB 50458 551 17 ascribed ascribe VBN 50458 551 18 to to IN 50458 551 19 albuminoids albuminoid NNS 50458 551 20 ( ( -LRB- 50458 551 21 phallin phallin NNP 50458 551 22 and and CC 50458 551 23 albumose albumose NNP 50458 551 24 ) ) -RRB- 50458 551 25 , , , 50458 551 26 alkaloids alkaloids NNP 50458 551 27 ( ( -LRB- 50458 551 28 muscarine muscarine NNP 50458 551 29 , , , 50458 551 30 choline choline NNP 50458 551 31 , , , 50458 551 32 or or CC 50458 551 33 betaine betaine JJ 50458 551 34 ) ) -RRB- 50458 551 35 , , , 50458 551 36 or or CC 50458 551 37 to to IN 50458 551 38 resinoids resinoid NNS 50458 551 39 ( ( -LRB- 50458 551 40 cambogic cambogic NNP 50458 551 41 and and CC 50458 551 42 agaricic agaricic NNP 50458 551 43 acids acids NNP 50458 551 44 ) ) -RRB- 50458 551 45 . . . 50458 552 1 The the DT 50458 552 2 _ _ NNP 50458 552 3 alkaloids alkaloid VBZ 50458 552 4 _ _ NNP 50458 552 5 found find VBD 50458 552 6 in in IN 50458 552 7 mushrooms mushroom NNS 50458 552 8 are be VBP 50458 552 9 : : : 50458 552 10 _ _ NNP 50458 552 11 Muscaridine Muscaridine NNP 50458 552 12 _ _ NNP 50458 552 13 ( ( -LRB- 50458 552 14 an an DT 50458 552 15 oxyneurine oxyneurine NN 50458 552 16 ) ) -RRB- 50458 552 17 , , , 50458 552 18 which which WDT 50458 552 19 possesses possess VBZ 50458 552 20 considerable considerable JJ 50458 552 21 toxicity toxicity NN 50458 552 22 , , , 50458 552 23 and and CC 50458 552 24 of of IN 50458 552 25 which which WDT 50458 552 26 0.00005 0.00005 NNP 50458 552 27 Gm Gm NNP 50458 552 28 . . . 50458 553 1 suffices suffice VBZ 50458 553 2 to to TO 50458 553 3 kill kill VB 50458 553 4 a a DT 50458 553 5 frog frog NN 50458 553 6 ; ; : 50458 553 7 _ _ NNP 50458 553 8 neurine neurine NN 50458 553 9 _ _ NNP 50458 553 10 ( ( -LRB- 50458 553 11 trimethylethylammonium trimethylethylammonium NNP 50458 553 12 hydroxide hydroxide NNP 50458 553 13 ) ) -RRB- 50458 553 14 ; ; : 50458 553 15 _ _ NNP 50458 553 16 choline choline NN 50458 553 17 _ _ NNP 50458 553 18 ( ( -LRB- 50458 553 19 trimethyloxyethylammonium trimethyloxyethylammonium NN 50458 553 20 hydroxide hydroxide NN 50458 553 21 ) ) -RRB- 50458 553 22 ; ; : 50458 553 23 _ _ NNP 50458 553 24 mycetomuscarine mycetomuscarine NNP 50458 553 25 _ _ NNP 50458 553 26 ; ; : 50458 553 27 _ _ NNP 50458 553 28 anhydromuscarine anhydromuscarine NN 50458 553 29 _ _ NNP 50458 553 30 ( ( -LRB- 50458 553 31 an an DT 50458 553 32 oxyneurine oxyneurine NN 50458 553 33 ) ) -RRB- 50458 553 34 ; ; : 50458 553 35 and and CC 50458 553 36 a a DT 50458 553 37 whole whole JJ 50458 553 38 series series NN 50458 553 39 of of IN 50458 553 40 various various JJ 50458 553 41 betaines betaine NNS 50458 553 42 . . . 50458 554 1 = = NFP 50458 554 2 Symptomology.=--It Symptomology.=--It NNP 50458 554 3 is be VBZ 50458 554 4 quite quite RB 50458 554 5 natural natural JJ 50458 554 6 to to TO 50458 554 7 divide divide VB 50458 554 8 this this DT 50458 554 9 symptomology symptomology NN 50458 554 10 into into IN 50458 554 11 three three CD 50458 554 12 different different JJ 50458 554 13 periods period NNS 50458 554 14 ; ; : 50458 554 15 that that DT 50458 554 16 of of IN 50458 554 17 incubation incubation NN 50458 554 18 , , , 50458 554 19 that that DT 50458 554 20 of of IN 50458 554 21 manifestation manifestation NN 50458 554 22 of of IN 50458 554 23 symptoms symptom NNS 50458 554 24 , , , 50458 554 25 and and CC 50458 554 26 that that DT 50458 554 27 of of IN 50458 554 28 termination termination NN 50458 554 29 . . . 50458 555 1 The the DT 50458 555 2 duration duration NN 50458 555 3 of of IN 50458 555 4 the the DT 50458 555 5 first first JJ 50458 555 6 period period NN 50458 555 7 , , , 50458 555 8 that that DT 50458 555 9 of of IN 50458 555 10 incubation incubation NN 50458 555 11 , , , 50458 555 12 is be VBZ 50458 555 13 exceedingly exceedingly RB 50458 555 14 variable variable JJ 50458 555 15 ; ; : 50458 555 16 it -PRON- PRP 50458 555 17 very very RB 50458 555 18 rarely rarely RB 50458 555 19 lasts last VBZ 50458 555 20 more more JJR 50458 555 21 than than IN 50458 555 22 forty forty CD 50458 555 23 - - HYPH 50458 555 24 eight eight CD 50458 555 25 hours hour NNS 50458 555 26 , , , 50458 555 27 and and CC 50458 555 28 becomes become VBZ 50458 555 29 general general JJ 50458 555 30 only only RB 50458 555 31 a a DT 50458 555 32 few few JJ 50458 555 33 hours hour NNS 50458 555 34 after after IN 50458 555 35 absorption absorption NN 50458 555 36 . . . 50458 556 1 Certain certain JJ 50458 556 2 conditions condition NNS 50458 556 3 influence influence VBP 50458 556 4 the the DT 50458 556 5 duration duration NN 50458 556 6 ; ; : 50458 556 7 firstly firstly RB 50458 556 8 the the DT 50458 556 9 quantity quantity NN 50458 556 10 of of IN 50458 556 11 mushrooms mushroom NNS 50458 556 12 ingested ingest VBN 50458 556 13 , , , 50458 556 14 then then RB 50458 556 15 the the DT 50458 556 16 manner manner NN 50458 556 17 in in IN 50458 556 18 which which WDT 50458 556 19 they -PRON- PRP 50458 556 20 were be VBD 50458 556 21 prepared prepare VBN 50458 556 22 ; ; : 50458 556 23 and and CC 50458 556 24 , , , 50458 556 25 to to IN 50458 556 26 some some DT 50458 556 27 extent extent NN 50458 556 28 , , , 50458 556 29 the the DT 50458 556 30 nature nature NN 50458 556 31 of of IN 50458 556 32 the the DT 50458 556 33 organism organism NN 50458 556 34 , , , 50458 556 35 whether whether IN 50458 556 36 child child NN 50458 556 37 or or CC 50458 556 38 adult adult NN 50458 556 39 , , , 50458 556 40 healthy healthy JJ 50458 556 41 or or CC 50458 556 42 in in IN 50458 556 43 poor poor JJ 50458 556 44 health health NN 50458 556 45 . . . 50458 557 1 When when WRB 50458 557 2 it -PRON- PRP 50458 557 3 is be VBZ 50458 557 4 a a DT 50458 557 5 question question NN 50458 557 6 of of IN 50458 557 7 the the DT 50458 557 8 more more RBR 50458 557 9 particularly particularly RB 50458 557 10 alkaloid alkaloid RB 50458 557 11 - - HYPH 50458 557 12 containing contain VBG 50458 557 13 mushrooms mushroom NNS 50458 557 14 , , , 50458 557 15 especially especially RB 50458 557 16 when when WRB 50458 557 17 the the DT 50458 557 18 poisoning poisoning NN 50458 557 19 is be VBZ 50458 557 20 due due JJ 50458 557 21 to to IN 50458 557 22 muscarine muscarine NN 50458 557 23 , , , 50458 557 24 the the DT 50458 557 25 toxic toxic JJ 50458 557 26 symptoms symptom NNS 50458 557 27 generally generally RB 50458 557 28 develop develop VBP 50458 557 29 rapidly rapidly RB 50458 557 30 , , , 50458 557 31 the the DT 50458 557 32 first first JJ 50458 557 33 symptoms symptom NNS 50458 557 34 appearing appear VBG 50458 557 35 about about RB 50458 557 36 one one CD 50458 557 37 hour hour NN 50458 557 38 after after IN 50458 557 39 the the DT 50458 557 40 ingestion ingestion NN 50458 557 41 of of IN 50458 557 42 the the DT 50458 557 43 mushrooms mushroom NNS 50458 557 44 . . . 50458 558 1 On on IN 50458 558 2 the the DT 50458 558 3 other other JJ 50458 558 4 hand hand NN 50458 558 5 , , , 50458 558 6 if if IN 50458 558 7 the the DT 50458 558 8 poisoning poisoning NN 50458 558 9 is be VBZ 50458 558 10 due due JJ 50458 558 11 to to IN 50458 558 12 one one CD 50458 558 13 of of IN 50458 558 14 the the DT 50458 558 15 albuminoid albuminoid NN 50458 558 16 group group NNP 50458 558 17 , , , 50458 558 18 and and CC 50458 558 19 particularly particularly RB 50458 558 20 in in IN 50458 558 21 the the DT 50458 558 22 case case NN 50458 558 23 of of IN 50458 558 24 phallin phallin NNP 50458 558 25 , , , 50458 558 26 the the DT 50458 558 27 period period NN 50458 558 28 of of IN 50458 558 29 incubation incubation NN 50458 558 30 is be VBZ 50458 558 31 longer long JJR 50458 558 32 , , , 50458 558 33 and and CC 50458 558 34 may may MD 50458 558 35 last last VB 50458 558 36 ten ten CD 50458 558 37 , , , 50458 558 38 twenty twenty CD 50458 558 39 , , , 50458 558 40 thirty thirty CD 50458 558 41 , , , 50458 558 42 or or CC 50458 558 43 even even RB 50458 558 44 forty forty CD 50458 558 45 - - HYPH 50458 558 46 eight eight CD 50458 558 47 hours hour NNS 50458 558 48 and and CC 50458 558 49 more more JJR 50458 558 50 . . . 50458 559 1 The the DT 50458 559 2 symptoms symptom NNS 50458 559 3 begin begin VBP 50458 559 4 with with IN 50458 559 5 dizziness dizziness NN 50458 559 6 and and CC 50458 559 7 an an DT 50458 559 8 indefinable indefinable JJ 50458 559 9 sensation sensation NN 50458 559 10 of of IN 50458 559 11 being be VBG 50458 559 12 ill ill JJ 50458 559 13 . . . 50458 560 1 The the DT 50458 560 2 second second JJ 50458 560 3 period period NN 50458 560 4 is be VBZ 50458 560 5 characterized characterize VBN 50458 560 6 chiefly chiefly RB 50458 560 7 by by IN 50458 560 8 digestive digestive JJ 50458 560 9 and and CC 50458 560 10 by by IN 50458 560 11 nervous nervous JJ 50458 560 12 derangements derangement NNS 50458 560 13 . . . 50458 561 1 The the DT 50458 561 2 digestive digestive JJ 50458 561 3 derangements derangement NNS 50458 561 4 are be VBP 50458 561 5 evidenced evidence VBN 50458 561 6 by by IN 50458 561 7 very very RB 50458 561 8 violent violent JJ 50458 561 9 and and CC 50458 561 10 painful painful JJ 50458 561 11 vomiting vomiting NN 50458 561 12 , , , 50458 561 13 and and CC 50458 561 14 diarrheas diarrhea NNS 50458 561 15 of of IN 50458 561 16 choleraic choleraic NN 50458 561 17 or or CC 50458 561 18 dysenteric dysenteric JJ 50458 561 19 character character NN 50458 561 20 . . . 50458 562 1 The the DT 50458 562 2 nervous nervous JJ 50458 562 3 derangements derangement NNS 50458 562 4 vary vary VBP 50458 562 5 according accord VBG 50458 562 6 to to IN 50458 562 7 whether whether IN 50458 562 8 they -PRON- PRP 50458 562 9 are be VBP 50458 562 10 developed develop VBN 50458 562 11 by by IN 50458 562 12 an an DT 50458 562 13 alkaloid alkaloid NN 50458 562 14 , , , 50458 562 15 which which WDT 50458 562 16 causes cause VBZ 50458 562 17 delirium delirium NN 50458 562 18 with with IN 50458 562 19 hallucination hallucination NN 50458 562 20 , , , 50458 562 21 or or CC 50458 562 22 by by IN 50458 562 23 albuminoids albuminoid NNS 50458 562 24 , , , 50458 562 25 which which WDT 50458 562 26 cause cause VBP 50458 562 27 depression depression NN 50458 562 28 , , , 50458 562 29 ataxo ataxo JJ 50458 562 30 - - HYPH 50458 562 31 adynamia adynamia NN 50458 562 32 , , , 50458 562 33 and and CC 50458 562 34 stupor stupor NN 50458 562 35 , , , 50458 562 36 these these DT 50458 562 37 being be VBG 50458 562 38 particularly particularly RB 50458 562 39 characteristic characteristic JJ 50458 562 40 of of IN 50458 562 41 the the DT 50458 562 42 action action NN 50458 562 43 of of IN 50458 562 44 the the DT 50458 562 45 toxic toxic JJ 50458 562 46 albuminoids albuminoid NNS 50458 562 47 . . . 50458 563 1 As as IN 50458 563 2 for for IN 50458 563 3 the the DT 50458 563 4 period period NN 50458 563 5 of of IN 50458 563 6 termination termination NN 50458 563 7 , , , 50458 563 8 it -PRON- PRP 50458 563 9 results result VBZ 50458 563 10 either either CC 50458 563 11 in in IN 50458 563 12 death death NN 50458 563 13 or or CC 50458 563 14 a a DT 50458 563 15 cure cure NN 50458 563 16 . . . 50458 564 1 If if IN 50458 564 2 the the DT 50458 564 3 poisoning poisoning NN 50458 564 4 is be VBZ 50458 564 5 due due JJ 50458 564 6 to to IN 50458 564 7 phallin phallin NN 50458 564 8 , , , 50458 564 9 death death NN 50458 564 10 appears appear VBZ 50458 564 11 to to TO 50458 564 12 be be VB 50458 564 13 an an DT 50458 564 14 almost almost RB 50458 564 15 inevitable inevitable JJ 50458 564 16 consequence consequence NN 50458 564 17 , , , 50458 564 18 as as IN 50458 564 19 it -PRON- PRP 50458 564 20 occurs occur VBZ 50458 564 21 in in IN 50458 564 22 80 80 CD 50458 564 23 per per NN 50458 564 24 cent cent NN 50458 564 25 . . . 50458 565 1 or or CC 50458 565 2 more more JJR 50458 565 3 of of IN 50458 565 4 the the DT 50458 565 5 cases case NNS 50458 565 6 . . . 50458 566 1 The the DT 50458 566 2 poisoning poisoning NN 50458 566 3 by by IN 50458 566 4 the the DT 50458 566 5 alkaloids alkaloid NNS 50458 566 6 is be VBZ 50458 566 7 less less RBR 50458 566 8 dangerous dangerous JJ 50458 566 9 , , , 50458 566 10 and and CC 50458 566 11 the the DT 50458 566 12 cure cure NN 50458 566 13 , , , 50458 566 14 when when WRB 50458 566 15 it -PRON- PRP 50458 566 16 does do VBZ 50458 566 17 occur occur VB 50458 566 18 , , , 50458 566 19 is be VBZ 50458 566 20 very very RB 50458 566 21 rapid rapid JJ 50458 566 22 , , , 50458 566 23 almost almost RB 50458 566 24 immediate immediate JJ 50458 566 25 , , , 50458 566 26 in in IN 50458 566 27 fact fact NN 50458 566 28 , , , 50458 566 29 while while IN 50458 566 30 in in IN 50458 566 31 the the DT 50458 566 32 case case NN 50458 566 33 of of IN 50458 566 34 the the DT 50458 566 35 toxic toxic JJ 50458 566 36 albuminoids albuminoid NNS 50458 566 37 the the DT 50458 566 38 cure cure NN 50458 566 39 is be VBZ 50458 566 40 very very RB 50458 566 41 slow slow JJ 50458 566 42 , , , 50458 566 43 and and CC 50458 566 44 attended attend VBN 50458 566 45 by by IN 50458 566 46 relapses relapse NNS 50458 566 47 . . . 50458 567 1 One one CD 50458 567 2 characteristic characteristic NN 50458 567 3 of of IN 50458 567 4 these these DT 50458 567 5 toxalbumins toxalbumin NNS 50458 567 6 is be VBZ 50458 567 7 that that IN 50458 567 8 they -PRON- PRP 50458 567 9 are be VBP 50458 567 10 apt apt JJ 50458 567 11 to to TO 50458 567 12 develop develop VB 50458 567 13 specific specific JJ 50458 567 14 antitoxalbumins antitoxalbumin NNS 50458 567 15 . . . 50458 568 1 This this DT 50458 568 2 fact fact NN 50458 568 3 has have VBZ 50458 568 4 been be VBN 50458 568 5 verified verify VBN 50458 568 6 not not RB 50458 568 7 only only RB 50458 568 8 in in IN 50458 568 9 the the DT 50458 568 10 case case NN 50458 568 11 of of IN 50458 568 12 abrin abrin NNP 50458 568 13 , , , 50458 568 14 ricin ricin NNP 50458 568 15 , , , 50458 568 16 robin robin NNP 50458 568 17 , , , 50458 568 18 and and CC 50458 568 19 their -PRON- PRP$ 50458 568 20 analogues analogue NNS 50458 568 21 , , , 50458 568 22 but but CC 50458 568 23 also also RB 50458 568 24 in in IN 50458 568 25 that that DT 50458 568 26 of of IN 50458 568 27 the the DT 50458 568 28 vegetable vegetable NN 50458 568 29 and and CC 50458 568 30 animal animal NN 50458 568 31 diastases diastasis NNS 50458 568 32 possessing possess VBG 50458 568 33 toxic toxic JJ 50458 568 34 properties property NNS 50458 568 35 even even RB 50458 568 36 in in IN 50458 568 37 the the DT 50458 568 38 slightest slight JJS 50458 568 39 degree degree NN 50458 568 40 only only RB 50458 568 41 . . . 50458 569 1 These these DT 50458 569 2 antibodies antibody NNS 50458 569 3 generally generally RB 50458 569 4 exhibit exhibit VBP 50458 569 5 their -PRON- PRP$ 50458 569 6 action action NN 50458 569 7 _ _ NNP 50458 569 8 in in IN 50458 569 9 vitro vitro FW 50458 569 10 _ _ NNP 50458 569 11 . . . 50458 570 1 Thus thus RB 50458 570 2 antiricin antiricin VBZ 50458 570 3 exerts exert NNS 50458 570 4 its -PRON- PRP$ 50458 570 5 antiagglutinative antiagglutinative JJ 50458 570 6 action action NN 50458 570 7 on on IN 50458 570 8 the the DT 50458 570 9 erythrocytes erythrocyte NNS 50458 570 10 _ _ NNP 50458 570 11 in in IN 50458 570 12 vitro vitro FW 50458 570 13 _ _ NNP 50458 570 14 in in IN 50458 570 15 a a DT 50458 570 16 saline saline JJ 50458 570 17 medium medium NN 50458 570 18 in in IN 50458 570 19 which which WDT 50458 570 20 the the DT 50458 570 21 erythrocytes erythrocyte NNS 50458 570 22 can can MD 50458 570 23 not not RB 50458 570 24 live live VB 50458 570 25 . . . 50458 571 1 Here here RB 50458 571 2 , , , 50458 571 3 again again RB 50458 571 4 , , , 50458 571 5 as as IN 50458 571 6 in in IN 50458 571 7 the the DT 50458 571 8 case case NN 50458 571 9 of of IN 50458 571 10 the the DT 50458 571 11 antitoxins antitoxin NNS 50458 571 12 , , , 50458 571 13 it -PRON- PRP 50458 571 14 must must MD 50458 571 15 be be VB 50458 571 16 admitted admit VBN 50458 571 17 that that IN 50458 571 18 the the DT 50458 571 19 antitoxalbumin antitoxalbumin NN 50458 571 20 possesses possess VBZ 50458 571 21 a a DT 50458 571 22 specific specific JJ 50458 571 23 affinity affinity NN 50458 571 24 by by IN 50458 571 25 virtue virtue NN 50458 571 26 of of IN 50458 571 27 which which WDT 50458 571 28 it -PRON- PRP 50458 571 29 unites unite VBZ 50458 571 30 chemically chemically RB 50458 571 31 with with IN 50458 571 32 the the DT 50458 571 33 toxalbumin toxalbumin NN 50458 571 34 to to TO 50458 571 35 give give VB 50458 571 36 rise rise NN 50458 571 37 to to IN 50458 571 38 a a DT 50458 571 39 new new JJ 50458 571 40 substance substance NN 50458 571 41 which which WDT 50458 571 42 is be VBZ 50458 571 43 devoid devoid JJ 50458 571 44 of of IN 50458 571 45 toxicity toxicity NN 50458 571 46 . . . 50458 572 1 The the DT 50458 572 2 first first JJ 50458 572 3 antidiastase antidiastase NN 50458 572 4 obtained obtain VBN 50458 572 5 by by IN 50458 572 6 immunization immunization NN 50458 572 7 methods method NNS 50458 572 8 , , , 50458 572 9 and and CC 50458 572 10 according accord VBG 50458 572 11 to to IN 50458 572 12 the the DT 50458 572 13 mechanism mechanism NN 50458 572 14 we -PRON- PRP 50458 572 15 have have VBP 50458 572 16 already already RB 50458 572 17 seen see VBN 50458 572 18 , , , 50458 572 19 was be VBD 50458 572 20 _ _ NNP 50458 572 21 antiemulsin antiemulsin NN 50458 572 22 _ _ NNP 50458 572 23 , , , 50458 572 24 obtained obtain VBN 50458 572 25 by by IN 50458 572 26 Hildebrandt Hildebrandt NNP 50458 572 27 . . . 50458 573 1 [ [ -LRB- 50458 573 2 62 62 CD 50458 573 3 ] ] -RRB- 50458 573 4 This this DT 50458 573 5 antiemulsin antiemulsin NN 50458 573 6 counteracts counteract NNS 50458 573 7 , , , 50458 573 8 both both CC 50458 573 9 _ _ NNP 50458 573 10 in in IN 50458 573 11 vivo vivo NNP 50458 573 12 _ _ NNP 50458 573 13 and and CC 50458 573 14 _ _ NNP 50458 573 15 in in IN 50458 573 16 vitro vitro FW 50458 573 17 _ _ NNP 50458 573 18 , , , 50458 573 19 the the DT 50458 573 20 specific specific JJ 50458 573 21 action action NN 50458 573 22 of of IN 50458 573 23 emulsin emulsin NNP 50458 573 24 . . . 50458 574 1 These these DT 50458 574 2 studies study NNS 50458 574 3 have have VBP 50458 574 4 been be VBN 50458 574 5 followed follow VBN 50458 574 6 by by IN 50458 574 7 a a DT 50458 574 8 large large JJ 50458 574 9 number number NN 50458 574 10 of of IN 50458 574 11 scientists scientist NNS 50458 574 12 , , , 50458 574 13 particularly particularly RB 50458 574 14 by by IN 50458 574 15 Camus Camus NNP 50458 574 16 and and CC 50458 574 17 Gley,[63 Gley,[63 NNP 50458 574 18 ] ] -RRB- 50458 574 19 Carnot Carnot NNP 50458 574 20 , , , 50458 574 21 Mesnil,[64 Mesnil,[64 NNP 50458 574 22 ] ] -RRB- 50458 574 23 and and CC 50458 574 24 Charron Charron NNP 50458 574 25 and and CC 50458 574 26 Levaditi,[65 Levaditi,[65 NNP 50458 574 27 ] ] -RRB- 50458 574 28 in in IN 50458 574 29 the the DT 50458 574 30 case case NN 50458 574 31 of of IN 50458 574 32 trypsin trypsin NNP 50458 574 33 ; ; : 50458 574 34 and and CC 50458 574 35 Sachs[66 sachs[66 ADD 50458 574 36 ] ] -RRB- 50458 574 37 in in IN 50458 574 38 the the DT 50458 574 39 case case NN 50458 574 40 of of IN 50458 574 41 animal animal NN 50458 574 42 pepsin pepsin NN 50458 574 43 . . . 50458 575 1 Gessard[67 gessard[67 ADD 50458 575 2 ] ] -RRB- 50458 575 3 obtained obtain VBN 50458 575 4 a a DT 50458 575 5 very very RB 50458 575 6 active active JJ 50458 575 7 _ _ NNP 50458 575 8 antityrosinase antityrosinase NN 50458 575 9 _ _ NNP 50458 575 10 , , , 50458 575 11 and and CC 50458 575 12 Mohl Mohl NNP 50458 575 13 an an DT 50458 575 14 _ _ NNP 50458 575 15 antiurease antiurease NN 50458 575 16 _ _ NNP 50458 575 17 . . . 50458 576 1 [ [ -LRB- 50458 576 2 62 62 CD 50458 576 3 ] ] -RRB- 50458 576 4 HILDEBRANDT hildebrandt NN 50458 576 5 : : : 50458 576 6 Weiteres weitere NNS 50458 576 7 über über NN 50458 576 8 hydrolyt hydrolyt NN 50458 576 9 . . . 50458 577 1 Fermente Fermente NNP 50458 577 2 , , , 50458 577 3 etc etc FW 50458 577 4 . . . 50458 578 1 _ _ NNP 50458 578 2 Virch Virch NNP 50458 578 3 . . . 50458 579 1 Arch Arch NNP 50458 579 2 . . . 50458 579 3 _ _ NNP 50458 579 4 , , , 50458 579 5 CXXXI CXXXI NNP 50458 579 6 , , , 50458 579 7 1895 1895 CD 50458 579 8 , , , 50458 579 9 P. P. NNP 50458 579 10 5 5 CD 50458 579 11 . . . 50458 580 1 [ [ -LRB- 50458 580 2 63 63 CD 50458 580 3 ] ] -RRB- 50458 580 4 CAMUS CAMUS NNP 50458 580 5 and and CC 50458 580 6 GLEY GLEY NNP 50458 580 7 : : : 50458 580 8 _ _ NNP 50458 580 9 Compt Compt NNP 50458 580 10 . . . 50458 581 1 rend rend VB 50458 581 2 . . . 50458 582 1 de de NNP 50458 582 2 la la NNP 50458 582 3 Soc Soc NNP 50458 582 4 . . . 50458 583 1 de de NNP 50458 583 2 Biolog Biolog NNP 50458 583 3 . . . 50458 583 4 _ _ NNP 50458 583 5 , , , 50458 583 6 1897 1897 CD 50458 583 7 . . . 50458 584 1 [ [ -LRB- 50458 584 2 64 64 CD 50458 584 3 ] ] -RRB- 50458 584 4 MESNIL mesnil NN 50458 584 5 : : : 50458 584 6 Sur sur NN 50458 584 7 la la JJ 50458 584 8 digestion digestion NN 50458 584 9 des des FW 50458 584 10 actinies actinie NNS 50458 584 11 . . . 50458 585 1 _ _ NNP 50458 585 2 Annales Annales NNP 50458 585 3 de de NNP 50458 585 4 l'Institut l'Institut NNP 50458 585 5 Pasteur Pasteur NNP 50458 585 6 _ _ NNP 50458 585 7 , , , 50458 585 8 1901 1901 CD 50458 585 9 . . . 50458 586 1 [ [ -LRB- 50458 586 2 65 65 CD 50458 586 3 ] ] -RRB- 50458 586 4 CHARRIN charrin NN 50458 586 5 and and CC 50458 586 6 LEVADITI levaditi NN 50458 586 7 : : : 50458 586 8 _ _ NNP 50458 586 9 Compt Compt NNP 50458 586 10 . . . 50458 587 1 rend rend VB 50458 587 2 . . . 50458 588 1 de de NNP 50458 588 2 l'Académie l'Académie NNP 50458 588 3 dest d JJS 50458 588 4 Sciences Sciences NNPS 50458 588 5 _ _ NNP 50458 588 6 , , , 50458 588 7 1900 1900 CD 50458 588 8 . . . 50458 589 1 [ [ -LRB- 50458 589 2 66 66 CD 50458 589 3 ] ] -RRB- 50458 589 4 SACHS SACHS NNP 50458 589 5 : : : 50458 589 6 Ueber Ueber NNP 50458 589 7 Antiseptika Antiseptika NNP 50458 589 8 . . . 50458 590 1 _ _ NNP 50458 590 2 Zeitschr Zeitschr NNP 50458 590 3 . . . 50458 591 1 f. f. NNP 50458 591 2 Biolog Biolog NNP 50458 591 3 . . . 50458 591 4 _ _ NNP 50458 591 5 , , , 50458 591 6 1901 1901 CD 50458 591 7 , , , 50458 591 8 XXVI XXVI NNP 50458 591 9 . . . 50458 592 1 [ [ -LRB- 50458 592 2 67 67 CD 50458 592 3 ] ] -RRB- 50458 592 4 GESSARD gessard NN 50458 592 5 : : : 50458 592 6 _ _ NNP 50458 592 7 Annales Annales NNP 50458 592 8 de de NNP 50458 592 9 l'Institut l'Institut NNP 50458 592 10 Pasteur Pasteur NNP 50458 592 11 _ _ NNP 50458 592 12 , , , 50458 592 13 1901 1901 CD 50458 592 14 , , , 50458 592 15 p. p. NN 50458 592 16 609 609 CD 50458 592 17 ; ; : 50458 592 18 _ _ NNP 50458 592 19 Comp Comp NNP 50458 592 20 . . . 50458 593 1 rend rend VB 50458 593 2 . . . 50458 594 1 de de NNP 50458 594 2 la la NNP 50458 594 3 Société Société NNP 50458 594 4 de de NNP 50458 594 5 Biologie Biologie NNP 50458 594 6 _ _ NNP 50458 594 7 , , , 50458 594 8 May May NNP 50458 594 9 , , , 50458 594 10 1902 1902 CD 50458 594 11 . . . 50458 595 1 The the DT 50458 595 2 most most RBS 50458 595 3 important important JJ 50458 595 4 researches research NNS 50458 595 5 regarding regard VBG 50458 595 6 this this DT 50458 595 7 subject subject NN 50458 595 8 have have VBP 50458 595 9 been be VBN 50458 595 10 published publish VBN 50458 595 11 by by IN 50458 595 12 Morgenroth Morgenroth NNP 50458 595 13 , , , 50458 595 14 Briot,[68 Briot,[68 NNP 50458 595 15 ] ] -RRB- 50458 595 16 and and CC 50458 595 17 Korschum[69 Korschum[69 NNP 50458 595 18 ] ] -RRB- 50458 595 19 on on IN 50458 595 20 _ _ NNP 50458 595 21 antilab antilab NNP 50458 595 22 _ _ NNP 50458 595 23 ( ( -LRB- 50458 595 24 or or CC 50458 595 25 _ _ NNP 50458 595 26 antirennet antirennet NN 50458 595 27 _ _ NNP 50458 595 28 ) ) -RRB- 50458 595 29 . . . 50458 596 1 The the DT 50458 596 2 researches research NNS 50458 596 3 of of IN 50458 596 4 these these DT 50458 596 5 authors author NNS 50458 596 6 have have VBP 50458 596 7 fully fully RB 50458 596 8 demonstrated demonstrate VBN 50458 596 9 that that IN 50458 596 10 there there EX 50458 596 11 is be VBZ 50458 596 12 considerable considerable JJ 50458 596 13 difference difference NN 50458 596 14 between between IN 50458 596 15 the the DT 50458 596 16 various various JJ 50458 596 17 rennets rennet NNS 50458 596 18 , , , 50458 596 19 which which WDT 50458 596 20 had have VBD 50458 596 21 heretofore heretofore RB 50458 596 22 been be VBN 50458 596 23 confounded confound VBN 50458 596 24 under under IN 50458 596 25 one one CD 50458 596 26 head head NN 50458 596 27 ; ; : 50458 596 28 thus thus RB 50458 596 29 there there EX 50458 596 30 is be VBZ 50458 596 31 no no DT 50458 596 32 difference difference NN 50458 596 33 whatever whatever WDT 50458 596 34 between between IN 50458 596 35 animal animal NN 50458 596 36 rennet rennet NN 50458 596 37 and and CC 50458 596 38 the the DT 50458 596 39 rennet rennet NN 50458 596 40 extracted extract VBN 50458 596 41 by by IN 50458 596 42 Rosetti[70 Rosetti[70 NNP 50458 596 43 ] ] -RRB- 50458 596 44 from from IN 50458 596 45 Cynara Cynara NNP 50458 596 46 cardunculus cardunculus NNP 50458 596 47 ( ( -LRB- 50458 596 48 cardoon cardoon NN 50458 596 49 ) ) -RRB- 50458 596 50 so so RB 50458 596 51 far far RB 50458 596 52 as as IN 50458 596 53 their -PRON- PRP$ 50458 596 54 coagulant coagulant JJ 50458 596 55 action action NN 50458 596 56 on on IN 50458 596 57 milk milk NN 50458 596 58 is be VBZ 50458 596 59 concerned concern VBN 50458 596 60 , , , 50458 596 61 yet yet CC 50458 596 62 each each DT 50458 596 63 yields yield VBZ 50458 596 64 an an DT 50458 596 65 antibody antibody NN 50458 596 66 which which WDT 50458 596 67 is be VBZ 50458 596 68 strictly strictly RB 50458 596 69 specific specific JJ 50458 596 70 to to IN 50458 596 71 itself -PRON- PRP 50458 596 72 . . . 50458 597 1 From from IN 50458 597 2 a a DT 50458 597 3 scientific scientific JJ 50458 597 4 point point NN 50458 597 5 of of IN 50458 597 6 view view NN 50458 597 7 we -PRON- PRP 50458 597 8 see see VBP 50458 597 9 , , , 50458 597 10 therefore therefore RB 50458 597 11 , , , 50458 597 12 that that IN 50458 597 13 the the DT 50458 597 14 preparation preparation NN 50458 597 15 of of IN 50458 597 16 antidiastases antidiastase NNS 50458 597 17 permits permit VBZ 50458 597 18 us -PRON- PRP 50458 597 19 to to TO 50458 597 20 differentiate differentiate VB 50458 597 21 certain certain JJ 50458 597 22 diastases diastasis NNS 50458 597 23 that that WDT 50458 597 24 could could MD 50458 597 25 otherwise otherwise RB 50458 597 26 not not RB 50458 597 27 be be VB 50458 597 28 differentiated differentiate VBN 50458 597 29 . . . 50458 598 1 [ [ -LRB- 50458 598 2 68 68 CD 50458 598 3 ] ] -RRB- 50458 598 4 BRIOT BRIOT NNP 50458 598 5 : : : 50458 598 6 Thèse Thèse NNP 50458 598 7 de de FW 50458 598 8 Doctorat Doctorat NNP 50458 598 9 ès ès NNP 50458 598 10 - - HYPH 50458 598 11 Sciences Sciences NNPS 50458 598 12 , , , 50458 598 13 Paris Paris NNP 50458 598 14 , , , 50458 598 15 1900 1900 CD 50458 598 16 . . . 50458 599 1 [ [ -LRB- 50458 599 2 69 69 CD 50458 599 3 ] ] -RRB- 50458 599 4 KORSCHUM KORSCHUM NNP 50458 599 5 : : : 50458 599 6 _ _ NNP 50458 599 7 Zeitschr Zeitschr NNP 50458 599 8 . . . 50458 600 1 f. f. NNP 50458 600 2 physiolog physiolog NNP 50458 600 3 . . . 50458 601 1 Chemie Chemie NNP 50458 601 2 _ _ NNP 50458 601 3 , , , 50458 601 4 1902 1902 CD 50458 601 5 , , , 50458 601 6 XXXI XXXI NNP 50458 601 7 . . . 50458 602 1 [ [ -LRB- 50458 602 2 70 70 CD 50458 602 3 ] ] -RRB- 50458 602 4 ROSETTI ROSETTI NNP 50458 602 5 : : : 50458 602 6 _ _ NNP 50458 602 7 L'Orosi L'Orosi NNP 50458 602 8 , , , 50458 602 9 giorn giorn NN 50458 602 10 . . . 50458 603 1 di di NNP 50458 603 2 chemica chemica NNP 50458 603 3 , , , 50458 603 4 farmacia farmacia NNP 50458 603 5 et et NNP 50458 603 6 scienza scienza NNP 50458 603 7 affini affini NNP 50458 603 8 _ _ NNP 50458 603 9 , , , 50458 603 10 1898 1898 CD 50458 603 11 . . . 50458 604 1 III iii CD 50458 604 2 . . . 50458 605 1 ANIMAL ANIMAL NNP 50458 605 2 TOXINS toxin NNS 50458 605 3 . . . 50458 606 1 As as IN 50458 606 2 we -PRON- PRP 50458 606 3 have have VBP 50458 606 4 shown show VBN 50458 606 5 at at IN 50458 606 6 the the DT 50458 606 7 beginning beginning NN 50458 606 8 of of IN 50458 606 9 this this DT 50458 606 10 chapter chapter NN 50458 606 11 , , , 50458 606 12 certain certain JJ 50458 606 13 diastases diastasis NNS 50458 606 14 , , , 50458 606 15 and and CC 50458 606 16 particularly particularly RB 50458 606 17 those those DT 50458 606 18 that that WDT 50458 606 19 are be VBP 50458 606 20 concerned concern VBN 50458 606 21 with with IN 50458 606 22 the the DT 50458 606 23 digestive digestive JJ 50458 606 24 processes process NNS 50458 606 25 , , , 50458 606 26 pepsin pepsin NNP 50458 606 27 , , , 50458 606 28 trypsin trypsin NNP 50458 606 29 , , , 50458 606 30 etc etc FW 50458 606 31 . . FW 50458 606 32 , , , 50458 606 33 and and CC 50458 606 34 which which WDT 50458 606 35 are be VBP 50458 606 36 produced produce VBN 50458 606 37 in in IN 50458 606 38 abundance abundance NN 50458 606 39 by by IN 50458 606 40 the the DT 50458 606 41 entire entire JJ 50458 606 42 living living NN 50458 606 43 organism organism NN 50458 606 44 , , , 50458 606 45 possess possess VBP 50458 606 46 quite quite RB 50458 606 47 clearly clearly RB 50458 606 48 defined define VBN 50458 606 49 toxic toxic JJ 50458 606 50 properties property NNS 50458 606 51 , , , 50458 606 52 and and CC 50458 606 53 sometimes sometimes RB 50458 606 54 to to TO 50458 606 55 even even RB 50458 606 56 a a DT 50458 606 57 considerable considerable JJ 50458 606 58 extent extent NN 50458 606 59 . . . 50458 607 1 [ [ -LRB- 50458 607 2 71 71 CD 50458 607 3 ] ] -RRB- 50458 607 4 [ [ -LRB- 50458 607 5 71 71 CD 50458 607 6 ] ] -RRB- 50458 607 7 GUSTAVE GUSTAVE NNP 50458 607 8 SAUX SAUX NNP 50458 607 9 : : : 50458 607 10 De De NNP 50458 607 11 la la NNP 50458 607 12 toxicité toxicité NNP 50458 607 13 des des FW 50458 607 14 produits produits NNP 50458 607 15 de de NNP 50458 607 16 la la NNP 50458 607 17 digestion digestion NNP 50458 607 18 peptique peptique NNP 50458 607 19 . . . 50458 608 1 _ _ NNP 50458 608 2 Thèse Thèse NNP 50458 608 3 de de NNP 50458 608 4 doctorat doctorat NNP 50458 608 5 _ _ NNP 50458 608 6 , , , 50458 608 7 Bordeaux Bordeaux NNP 50458 608 8 , , , 50458 608 9 1902 1902 CD 50458 608 10 . . . 50458 609 1 Hemialbumose hemialbumose UH 50458 609 2 , , , 50458 609 3 from from IN 50458 609 4 which which WDT 50458 609 5 peptones peptone NNS 50458 609 6 are be VBP 50458 609 7 formed form VBN 50458 609 8 , , , 50458 609 9 is be VBZ 50458 609 10 itself -PRON- PRP 50458 609 11 a a DT 50458 609 12 dangerous dangerous JJ 50458 609 13 toxin toxin NN 50458 609 14 . . . 50458 610 1 It -PRON- PRP 50458 610 2 is be VBZ 50458 610 3 generally generally RB 50458 610 4 believed believe VBN 50458 610 5 that that IN 50458 610 6 the the DT 50458 610 7 toxic toxic JJ 50458 610 8 action action NN 50458 610 9 of of IN 50458 610 10 the the DT 50458 610 11 peptones peptone NNS 50458 610 12 and and CC 50458 610 13 of of IN 50458 610 14 the the DT 50458 610 15 products product NNS 50458 610 16 of of IN 50458 610 17 digestion digestion NN 50458 610 18 of of IN 50458 610 19 the the DT 50458 610 20 albuminoids albuminoid NNS 50458 610 21 is be VBZ 50458 610 22 due due JJ 50458 610 23 not not RB 50458 610 24 to to IN 50458 610 25 the the DT 50458 610 26 peptone peptone NN 50458 610 27 itself -PRON- PRP 50458 610 28 , , , 50458 610 29 but but CC 50458 610 30 to to IN 50458 610 31 the the DT 50458 610 32 more more RBR 50458 610 33 advanced advanced JJ 50458 610 34 products product NNS 50458 610 35 of of IN 50458 610 36 digestion digestion NN 50458 610 37 , , , 50458 610 38 alkaloidal alkaloidal NN 50458 610 39 products product NNS 50458 610 40 unquestionably unquestionably RB 50458 610 41 closely closely RB 50458 610 42 allied ally VBN 50458 610 43 to to IN 50458 610 44 the the DT 50458 610 45 ptomaines ptomaine NNS 50458 610 46 . . . 50458 611 1 Nevertheless nevertheless RB 50458 611 2 , , , 50458 611 3 the the DT 50458 611 4 true true JJ 50458 611 5 peptones peptone NNS 50458 611 6 behave behave VBP 50458 611 7 just just RB 50458 611 8 like like IN 50458 611 9 true true JJ 50458 611 10 poisons poison NNS 50458 611 11 , , , 50458 611 12 when when WRB 50458 611 13 they -PRON- PRP 50458 611 14 are be VBP 50458 611 15 introduced introduce VBN 50458 611 16 hypodermically hypodermically RB 50458 611 17 into into IN 50458 611 18 the the DT 50458 611 19 blood blood NN 50458 611 20 . . . 50458 612 1 [ [ -LRB- 50458 612 2 72 72 CD 50458 612 3 ] ] -RRB- 50458 612 4 [ [ -LRB- 50458 612 5 72 72 CD 50458 612 6 ] ] -RRB- 50458 612 7 SCHMIDT schmidt NN 50458 612 8 : : : 50458 612 9 _ _ NNP 50458 612 10 Mühlheim Mühlheim NNP 50458 612 11 , , , 50458 612 12 Arch Arch NNP 50458 612 13 . . . 50458 613 1 de de NNP 50458 613 2 physiol physiol NNP 50458 613 3 . . . 50458 613 4 _ _ NNP 50458 613 5 , , , 50458 613 6 1880 1880 CD 50458 613 7 . . . 50458 614 1 Brieger Brieger NNP 50458 614 2 has have VBZ 50458 614 3 made make VBN 50458 614 4 us -PRON- PRP 50458 614 5 acquainted acquaint VBN 50458 614 6 with with IN 50458 614 7 a a DT 50458 614 8 non non JJ 50458 614 9 - - JJ 50458 614 10 proteid proteid JJ 50458 614 11 substance substance NN 50458 614 12 , , , 50458 614 13 under under IN 50458 614 14 the the DT 50458 614 15 name name NN 50458 614 16 of of IN 50458 614 17 " " `` 50458 614 18 peptotoxin peptotoxin NN 50458 614 19 , , , 50458 614 20 " " '' 50458 614 21 which which WDT 50458 614 22 is be VBZ 50458 614 23 met meet VBN 50458 614 24 with with IN 50458 614 25 at at IN 50458 614 26 the the DT 50458 614 27 beginning beginning NN 50458 614 28 of of IN 50458 614 29 the the DT 50458 614 30 putrefaction putrefaction NN 50458 614 31 of of IN 50458 614 32 albuminoids albuminoid NNS 50458 614 33 . . . 50458 615 1 This this DT 50458 615 2 toxin toxin NN 50458 615 3 , , , 50458 615 4 which which WDT 50458 615 5 is be VBZ 50458 615 6 not not RB 50458 615 7 a a DT 50458 615 8 protein protein NN 50458 615 9 , , , 50458 615 10 is be VBZ 50458 615 11 nothing nothing NN 50458 615 12 else else RB 50458 615 13 but but CC 50458 615 14 a a DT 50458 615 15 ptomaine ptomaine NN 50458 615 16 . . . 50458 616 1 It -PRON- PRP 50458 616 2 is be VBZ 50458 616 3 not not RB 50458 616 4 altered alter VBN 50458 616 5 by by IN 50458 616 6 heat heat NN 50458 616 7 , , , 50458 616 8 and and CC 50458 616 9 possesses possess VBZ 50458 616 10 a a DT 50458 616 11 very very RB 50458 616 12 high high JJ 50458 616 13 toxicity toxicity NN 50458 616 14 . . . 50458 617 1 Brieger Brieger NNP 50458 617 2 claims claim VBZ 50458 617 3 that that IN 50458 617 4 it -PRON- PRP 50458 617 5 is be VBZ 50458 617 6 a a DT 50458 617 7 hydroxylized hydroxylized JJ 50458 617 8 derivative derivative NN 50458 617 9 of of IN 50458 617 10 an an DT 50458 617 11 aromatic aromatic JJ 50458 617 12 amide amide NN 50458 617 13 . . . 50458 618 1 [ [ -LRB- 50458 618 2 73 73 CD 50458 618 3 ] ] -RRB- 50458 618 4 [ [ -LRB- 50458 618 5 73 73 CD 50458 618 6 ] ] -RRB- 50458 618 7 BRIEGER BRIEGER NNP 50458 618 8 : : : 50458 618 9 _ _ NNP 50458 618 10 Berichte Berichte NNP 50458 618 11 d. d. NNP 50458 618 12 D. D. NNP 50458 618 13 chem chem NNP 50458 618 14 . . . 50458 619 1 Gesellsch Gesellsch NNP 50458 619 2 . . . 50458 619 3 _ _ NNP 50458 619 4 , , , 50458 619 5 XIX XIX NNP 50458 619 6 , , , 50458 619 7 p. p. NN 50458 619 8 3120 3120 CD 50458 619 9 ; ; : 50458 619 10 and and CC 50458 619 11 _ _ NNP 50458 619 12 Verhandl Verhandl NNP 50458 619 13 . . . 50458 620 1 d. d. NNP 50458 620 2 Congress Congress NNP 50458 620 3 f. f. NNP 50458 620 4 innere innere NNP 50458 620 5 Med Med NNP 50458 620 6 . . . 50458 620 7 _ _ NNP 50458 620 8 , , , 50458 620 9 II II NNP 50458 620 10 , , , 50458 620 11 p. p. NN 50458 620 12 277 277 CD 50458 620 13 . . . 50458 621 1 Besides besides IN 50458 621 2 these these DT 50458 621 3 facts fact NNS 50458 621 4 , , , 50458 621 5 experiment experiment NN 50458 621 6 has have VBZ 50458 621 7 shown show VBN 50458 621 8 that that IN 50458 621 9 the the DT 50458 621 10 leucocytes leucocyte NNS 50458 621 11 , , , 50458 621 12 or or CC 50458 621 13 white white JJ 50458 621 14 corpuscles corpuscle NNS 50458 621 15 , , , 50458 621 16 the the DT 50458 621 17 defensive defensive NN 50458 621 18 rôle rôle VBZ 50458 621 19 of of IN 50458 621 20 which which WDT 50458 621 21 we -PRON- PRP 50458 621 22 have have VBP 50458 621 23 noted note VBN 50458 621 24 in in IN 50458 621 25 phagocytosis phagocytosis NN 50458 621 26 , , , 50458 621 27 owe owe VBP 50458 621 28 their -PRON- PRP$ 50458 621 29 properties property NNS 50458 621 30 to to IN 50458 621 31 the the DT 50458 621 32 ferments ferment NNS 50458 621 33 which which WDT 50458 621 34 they -PRON- PRP 50458 621 35 secrete secrete VBP 50458 621 36 , , , 50458 621 37 and and CC 50458 621 38 particularly particularly RB 50458 621 39 to to IN 50458 621 40 some some DT 50458 621 41 of of IN 50458 621 42 the the DT 50458 621 43 digestive digestive JJ 50458 621 44 ferments ferment NNS 50458 621 45 . . . 50458 622 1 These these DT 50458 622 2 white white JJ 50458 622 3 corpuscles corpuscle NNS 50458 622 4 are be VBP 50458 622 5 very very RB 50458 622 6 rich rich JJ 50458 622 7 in in IN 50458 622 8 ferments ferment NNS 50458 622 9 of of IN 50458 622 10 all all DT 50458 622 11 kinds kind NNS 50458 622 12 . . . 50458 623 1 Rossbach Rossbach NNP 50458 623 2 found find VBD 50458 623 3 in in IN 50458 623 4 them -PRON- PRP 50458 623 5 amylase amylase RB 50458 623 6 ; ; : 50458 623 7 Achalme Achalme NNP 50458 623 8 found find VBD 50458 623 9 lipase lipase NN 50458 623 10 , , , 50458 623 11 casease casease VB 50458 623 12 , , , 50458 623 13 and and CC 50458 623 14 trypsin trypsin NN 50458 623 15 ; ; : 50458 623 16 and and CC 50458 623 17 the the DT 50458 623 18 study study NN 50458 623 19 of of IN 50458 623 20 immunity immunity NN 50458 623 21 has have VBZ 50458 623 22 brought bring VBN 50458 623 23 to to TO 50458 623 24 light light VB 50458 623 25 a a DT 50458 623 26 series series NN 50458 623 27 of of IN 50458 623 28 other other JJ 50458 623 29 ferments ferment NNS 50458 623 30 , , , 50458 623 31 the the DT 50458 623 32 alexins alexin NNS 50458 623 33 or or CC 50458 623 34 cytases cytase NNS 50458 623 35 ( ( -LRB- 50458 623 36 microcytase microcytase NN 50458 623 37 and and CC 50458 623 38 macrocytase macrocytase NNP 50458 623 39 ) ) -RRB- 50458 623 40 , , , 50458 623 41 which which WDT 50458 623 42 have have VBP 50458 623 43 an an DT 50458 623 44 exceedingly exceedingly RB 50458 623 45 important important JJ 50458 623 46 rôle rôle NN 50458 623 47 to to TO 50458 623 48 play play VB 50458 623 49 . . . 50458 624 1 It -PRON- PRP 50458 624 2 may may MD 50458 624 3 easily easily RB 50458 624 4 be be VB 50458 624 5 conceived conceive VBN 50458 624 6 that that IN 50458 624 7 under under IN 50458 624 8 certain certain JJ 50458 624 9 circumstances circumstance NNS 50458 624 10 a a DT 50458 624 11 part part NN 50458 624 12 or or CC 50458 624 13 the the DT 50458 624 14 whole whole NN 50458 624 15 of of IN 50458 624 16 these these DT 50458 624 17 ferments ferment NNS 50458 624 18 can can MD 50458 624 19 pass pass VB 50458 624 20 into into IN 50458 624 21 the the DT 50458 624 22 blood blood NN 50458 624 23 of of IN 50458 624 24 the the DT 50458 624 25 fluids fluid NNS 50458 624 26 of of IN 50458 624 27 the the DT 50458 624 28 body body NN 50458 624 29 , , , 50458 624 30 when when WRB 50458 624 31 they -PRON- PRP 50458 624 32 give give VBP 50458 624 33 rise rise NN 50458 624 34 to to IN 50458 624 35 serious serious JJ 50458 624 36 disturbances disturbance NNS 50458 624 37 in in IN 50458 624 38 certain certain JJ 50458 624 39 cases case NNS 50458 624 40 , , , 50458 624 41 or or CC 50458 624 42 confer confer VBP 50458 624 43 immunity immunity NN 50458 624 44 in in IN 50458 624 45 others other NNS 50458 624 46 . . . 50458 625 1 It -PRON- PRP 50458 625 2 is be VBZ 50458 625 3 thus thus RB 50458 625 4 that that IN 50458 625 5 , , , 50458 625 6 according accord VBG 50458 625 7 to to IN 50458 625 8 Gautier Gautier NNP 50458 625 9 , , , 50458 625 10 the the DT 50458 625 11 rise rise NN 50458 625 12 of of IN 50458 625 13 temperature temperature NN 50458 625 14 which which WDT 50458 625 15 characterizes characterize VBZ 50458 625 16 fever fever NN 50458 625 17 is be VBZ 50458 625 18 a a DT 50458 625 19 consequence consequence NN 50458 625 20 of of IN 50458 625 21 the the DT 50458 625 22 abnormal abnormal JJ 50458 625 23 transudation transudation NN 50458 625 24 of of IN 50458 625 25 these these DT 50458 625 26 normal normal JJ 50458 625 27 ferments ferment NNS 50458 625 28 into into IN 50458 625 29 the the DT 50458 625 30 blood blood NN 50458 625 31 , , , 50458 625 32 and and CC 50458 625 33 their -PRON- PRP$ 50458 625 34 transmission transmission NN 50458 625 35 by by IN 50458 625 36 the the DT 50458 625 37 general general JJ 50458 625 38 circulation circulation NN 50458 625 39 to to IN 50458 625 40 the the DT 50458 625 41 nervous nervous JJ 50458 625 42 centers center NNS 50458 625 43 . . . 50458 626 1 However however RB 50458 626 2 , , , 50458 626 3 it -PRON- PRP 50458 626 4 is be VBZ 50458 626 5 not not RB 50458 626 6 only only RB 50458 626 7 in in IN 50458 626 8 the the DT 50458 626 9 leucocytes leucocyte NNS 50458 626 10 that that IN 50458 626 11 we -PRON- PRP 50458 626 12 meet meet VBP 50458 626 13 with with IN 50458 626 14 these these DT 50458 626 15 toxic toxic JJ 50458 626 16 digestive digestive JJ 50458 626 17 ferments ferment NNS 50458 626 18 ; ; : 50458 626 19 it -PRON- PRP 50458 626 20 appears appear VBZ 50458 626 21 quite quite RB 50458 626 22 probable probable JJ 50458 626 23 , , , 50458 626 24 and and CC 50458 626 25 has have VBZ 50458 626 26 even even RB 50458 626 27 been be VBN 50458 626 28 partially partially RB 50458 626 29 demonstrated demonstrate VBN 50458 626 30 , , , 50458 626 31 that that IN 50458 626 32 they -PRON- PRP 50458 626 33 occur occur VBP 50458 626 34 in in IN 50458 626 35 a a DT 50458 626 36 large large JJ 50458 626 37 number number NN 50458 626 38 of of IN 50458 626 39 other other JJ 50458 626 40 cellular cellular JJ 50458 626 41 elements element NNS 50458 626 42 . . . 50458 627 1 It -PRON- PRP 50458 627 2 is be VBZ 50458 627 3 not not RB 50458 627 4 necessary necessary JJ 50458 627 5 here here RB 50458 627 6 to to TO 50458 627 7 dwell dwell VB 50458 627 8 upon upon IN 50458 627 9 the the DT 50458 627 10 formation formation NN 50458 627 11 of of IN 50458 627 12 the the DT 50458 627 13 antibodies antibody NNS 50458 627 14 of of IN 50458 627 15 this this DT 50458 627 16 group group NN 50458 627 17 of of IN 50458 627 18 active active JJ 50458 627 19 substances substance NNS 50458 627 20 . . . 50458 628 1 The the DT 50458 628 2 animal animal NN 50458 628 3 toxins toxin NNS 50458 628 4 are be VBP 50458 628 5 animal animal NN 50458 628 6 diastases diastasis NNS 50458 628 7 , , , 50458 628 8 and and CC 50458 628 9 we -PRON- PRP 50458 628 10 have have VBP 50458 628 11 seen see VBN 50458 628 12 in in IN 50458 628 13 the the DT 50458 628 14 preceding precede VBG 50458 628 15 paragraph paragraph NN 50458 628 16 that that IN 50458 628 17 these these DT 50458 628 18 substances substance NNS 50458 628 19 yield yield VBP 50458 628 20 specific specific JJ 50458 628 21 antibodies antibody NNS 50458 628 22 with with IN 50458 628 23 great great JJ 50458 628 24 facility facility NN 50458 628 25 . . . 50458 629 1 For for IN 50458 629 2 the the DT 50458 629 3 rest rest NN 50458 629 4 , , , 50458 629 5 we -PRON- PRP 50458 629 6 will will MD 50458 629 7 dwell dwell VB 50458 629 8 more more RBR 50458 629 9 fully fully RB 50458 629 10 on on IN 50458 629 11 these these DT 50458 629 12 antibodies antibody NNS 50458 629 13 of of IN 50458 629 14 the the DT 50458 629 15 animal animal NN 50458 629 16 toxins toxin NNS 50458 629 17 in in IN 50458 629 18 another another DT 50458 629 19 volume volume NN 50458 629 20 of of IN 50458 629 21 this this DT 50458 629 22 collection collection NN 50458 629 23 , , , 50458 629 24 specially specially RB 50458 629 25 devoted devoted JJ 50458 629 26 to to IN 50458 629 27 the the DT 50458 629 28 study study NN 50458 629 29 of of IN 50458 629 30 these these DT 50458 629 31 substances substance NNS 50458 629 32 , , , 50458 629 33 and and CC 50458 629 34 entitled entitle VBN 50458 629 35 " " `` 50458 629 36 _ _ NNP 50458 629 37 Les Les NNP 50458 629 38 Serums Serums NNP 50458 629 39 Immunisants Immunisants NNP 50458 629 40 _ _ NNP 50458 629 41 , , , 50458 629 42 " " '' 50458 629 43 to to TO 50458 629 44 which which WDT 50458 629 45 we -PRON- PRP 50458 629 46 refer refer VBP 50458 629 47 the the DT 50458 629 48 reader reader NN 50458 629 49 who who WP 50458 629 50 is be VBZ 50458 629 51 desirous desirous JJ 50458 629 52 of of IN 50458 629 53 obtaining obtain VBG 50458 629 54 more more RBR 50458 629 55 complete complete JJ 50458 629 56 details detail NNS 50458 629 57 than than IN 50458 629 58 he -PRON- PRP 50458 629 59 can can MD 50458 629 60 obtain obtain VB 50458 629 61 in in IN 50458 629 62 the the DT 50458 629 63 present present JJ 50458 629 64 volume volume NN 50458 629 65 . . . 50458 630 1 = = NFP 50458 630 2 Alimentary Alimentary NNP 50458 630 3 Intoxications.=--What Intoxications.=--What NNP 50458 630 4 we -PRON- PRP 50458 630 5 have have VBP 50458 630 6 already already RB 50458 630 7 stated state VBN 50458 630 8 permits permit VBZ 50458 630 9 us -PRON- PRP 50458 630 10 to to TO 50458 630 11 understand understand VB 50458 630 12 the the DT 50458 630 13 phenomena phenomenon NNS 50458 630 14 of of IN 50458 630 15 indigestion indigestion NN 50458 630 16 and and CC 50458 630 17 botulism botulism NN 50458 630 18 . . . 50458 631 1 The the DT 50458 631 2 toxic toxic JJ 50458 631 3 substances substance NNS 50458 631 4 form form VBP 50458 631 5 within within IN 50458 631 6 the the DT 50458 631 7 digestive digestive JJ 50458 631 8 tract tract NN 50458 631 9 when when WRB 50458 631 10 the the DT 50458 631 11 nervous nervous JJ 50458 631 12 conditions condition NNS 50458 631 13 modify modify VBP 50458 631 14 the the DT 50458 631 15 composition composition NN 50458 631 16 of of IN 50458 631 17 the the DT 50458 631 18 gastric gastric JJ 50458 631 19 juice juice NN 50458 631 20 , , , 50458 631 21 and and CC 50458 631 22 arrest arrest VB 50458 631 23 the the DT 50458 631 24 flow flow NN 50458 631 25 of of IN 50458 631 26 hydrochloric hydrochloric JJ 50458 631 27 acid acid NN 50458 631 28 , , , 50458 631 29 the the DT 50458 631 30 presence presence NN 50458 631 31 of of IN 50458 631 32 which which WDT 50458 631 33 normally normally RB 50458 631 34 checks check VBZ 50458 631 35 the the DT 50458 631 36 development development NN 50458 631 37 of of IN 50458 631 38 the the DT 50458 631 39 microbial microbial JJ 50458 631 40 flora flora NNS 50458 631 41 , , , 50458 631 42 so so RB 50458 631 43 rich rich JJ 50458 631 44 within within IN 50458 631 45 the the DT 50458 631 46 stomach stomach NN 50458 631 47 . . . 50458 632 1 The the DT 50458 632 2 result result NN 50458 632 3 is be VBZ 50458 632 4 the the DT 50458 632 5 production production NN 50458 632 6 , , , 50458 632 7 within within IN 50458 632 8 the the DT 50458 632 9 organism organism NN 50458 632 10 , , , 50458 632 11 of of IN 50458 632 12 all all DT 50458 632 13 kinds kind NNS 50458 632 14 of of IN 50458 632 15 dangerous dangerous JJ 50458 632 16 toxins toxin NNS 50458 632 17 . . . 50458 633 1 The the DT 50458 633 2 same same JJ 50458 633 3 thing thing NN 50458 633 4 happens happen VBZ 50458 633 5 when when WRB 50458 633 6 the the DT 50458 633 7 liver liver NN 50458 633 8 does do VBZ 50458 633 9 not not RB 50458 633 10 functionate functionate VB 50458 633 11 normally normally RB 50458 633 12 , , , 50458 633 13 and and CC 50458 633 14 this this DT 50458 633 15 , , , 50458 633 16 affords afford VBZ 50458 633 17 us -PRON- PRP 50458 633 18 a a DT 50458 633 19 knowledge knowledge NN 50458 633 20 of of IN 50458 633 21 the the DT 50458 633 22 mechanism mechanism NN 50458 633 23 by by IN 50458 633 24 which which WDT 50458 633 25 foods food NNS 50458 633 26 that that WDT 50458 633 27 are be VBP 50458 633 28 most most RBS 50458 633 29 wholesome wholesome JJ 50458 633 30 may may MD 50458 633 31 become become VB 50458 633 32 toxic toxic JJ 50458 633 33 by by IN 50458 633 34 reason reason NN 50458 633 35 of of IN 50458 633 36 poor poor JJ 50458 633 37 digestion digestion NN 50458 633 38 or or CC 50458 633 39 poor poor JJ 50458 633 40 assimilation assimilation NN 50458 633 41 . . . 50458 634 1 The the DT 50458 634 2 absorption absorption NN 50458 634 3 of of IN 50458 634 4 spoiled spoiled JJ 50458 634 5 viands viand NNS 50458 634 6 may may MD 50458 634 7 , , , 50458 634 8 _ _ NNP 50458 634 9 a a DT 50458 634 10 fortiori fortiori NN 50458 634 11 _ _ NNP 50458 634 12 , , , 50458 634 13 produce produce VBP 50458 634 14 serious serious JJ 50458 634 15 results result NNS 50458 634 16 . . . 50458 635 1 The the DT 50458 635 2 alteration alteration NN 50458 635 3 may may MD 50458 635 4 be be VB 50458 635 5 due due JJ 50458 635 6 not not RB 50458 635 7 only only RB 50458 635 8 to to IN 50458 635 9 a a DT 50458 635 10 bacterial bacterial JJ 50458 635 11 infection infection NN 50458 635 12 , , , 50458 635 13 as as IN 50458 635 14 in in IN 50458 635 15 tainted tainted JJ 50458 635 16 meat meat NN 50458 635 17 , , , 50458 635 18 but but CC 50458 635 19 it -PRON- PRP 50458 635 20 has have VBZ 50458 635 21 also also RB 50458 635 22 been be VBN 50458 635 23 proved prove VBN 50458 635 24 that that IN 50458 635 25 the the DT 50458 635 26 flesh flesh NN 50458 635 27 of of IN 50458 635 28 an an DT 50458 635 29 animal animal NN 50458 635 30 that that WDT 50458 635 31 has have VBZ 50458 635 32 died die VBN 50458 635 33 of of IN 50458 635 34 terror terror NN 50458 635 35 or or CC 50458 635 36 madness madness NN 50458 635 37 may may MD 50458 635 38 be be VB 50458 635 39 very very RB 50458 635 40 dangerous dangerous JJ 50458 635 41 as as IN 50458 635 42 a a DT 50458 635 43 food food NN 50458 635 44 , , , 50458 635 45 even even RB 50458 635 46 after after IN 50458 635 47 cooking cooking NN 50458 635 48 , , , 50458 635 49 because because IN 50458 635 50 , , , 50458 635 51 although although IN 50458 635 52 there there EX 50458 635 53 are be VBP 50458 635 54 toxins toxin NNS 50458 635 55 which which WDT 50458 635 56 are be VBP 50458 635 57 destroyed destroy VBN 50458 635 58 by by IN 50458 635 59 a a DT 50458 635 60 sufficient sufficient JJ 50458 635 61 heat heat NN 50458 635 62 , , , 50458 635 63 there there EX 50458 635 64 are be VBP 50458 635 65 ptomaines ptomaine NNS 50458 635 66 and and CC 50458 635 67 certain certain JJ 50458 635 68 toxins toxin NNS 50458 635 69 that that WDT 50458 635 70 resist resist VBP 50458 635 71 destruction destruction NN 50458 635 72 under under IN 50458 635 73 these these DT 50458 635 74 conditions condition NNS 50458 635 75 . . . 50458 636 1 [ [ -LRB- 50458 636 2 74 74 CD 50458 636 3 ] ] -RRB- 50458 636 4 [ [ -LRB- 50458 636 5 74 74 CD 50458 636 6 ] ] -RRB- 50458 636 7 POLLIN POLLIN NNP 50458 636 8 and and CC 50458 636 9 LABIT LABIT NNP 50458 636 10 : : : 50458 636 11 _ _ NNP 50458 636 12 Examens Examens NNP 50458 636 13 des des NNP 50458 636 14 aliments aliment NNS 50458 636 15 suspects suspect VBZ 50458 636 16 _ _ NNP 50458 636 17 , , , 50458 636 18 Masson Masson NNP 50458 636 19 , , , 50458 636 20 publisher publisher NN 50458 636 21 . . . 50458 637 1 The the DT 50458 637 2 use use NN 50458 637 3 of of IN 50458 637 4 preserved preserve VBN 50458 637 5 but but CC 50458 637 6 spoiled spoiled JJ 50458 637 7 beef beef NN 50458 637 8 , , , 50458 637 9 preserved preserve VBN 50458 637 10 ham ham NN 50458 637 11 or or CC 50458 637 12 birds bird NNS 50458 637 13 , , , 50458 637 14 sausages sausage NNS 50458 637 15 frequently frequently RB 50458 637 16 , , , 50458 637 17 and and CC 50458 637 18 pieces piece NNS 50458 637 19 of of IN 50458 637 20 pork pork NN 50458 637 21 tainted taint VBN 50458 637 22 by by IN 50458 637 23 sausage sausage NN 50458 637 24 poison poison NN 50458 637 25 , , , 50458 637 26 gives give VBZ 50458 637 27 rise rise NN 50458 637 28 to to IN 50458 637 29 a a DT 50458 637 30 succession succession NN 50458 637 31 of of IN 50458 637 32 toxic toxic JJ 50458 637 33 symptoms symptom NNS 50458 637 34 the the DT 50458 637 35 principal principal JJ 50458 637 36 ones one NNS 50458 637 37 of of IN 50458 637 38 which which WDT 50458 637 39 are be VBP 50458 637 40 dryness dryness NN 50458 637 41 , , , 50458 637 42 constriction constriction NN 50458 637 43 of of IN 50458 637 44 the the DT 50458 637 45 pharynx pharynx NN 50458 637 46 , , , 50458 637 47 bilious bilious JJ 50458 637 48 vomiting vomiting NN 50458 637 49 , , , 50458 637 50 diarrhea diarrhea NN 50458 637 51 , , , 50458 637 52 dyspnea dyspnea JJ 50458 637 53 with with IN 50458 637 54 pulmonary pulmonary JJ 50458 637 55 edema edema NN 50458 637 56 , , , 50458 637 57 etc etc FW 50458 637 58 . . . 50458 638 1 Fish fish NN 50458 638 2 and and CC 50458 638 3 eggs egg NNS 50458 638 4 are be VBP 50458 638 5 foods food NNS 50458 638 6 quite quite RB 50458 638 7 frequently frequently RB 50458 638 8 capable capable JJ 50458 638 9 of of IN 50458 638 10 developing develop VBG 50458 638 11 serious serious JJ 50458 638 12 results result NNS 50458 638 13 ; ; : 50458 638 14 the the DT 50458 638 15 same same JJ 50458 638 16 is be VBZ 50458 638 17 the the DT 50458 638 18 case case NN 50458 638 19 with with IN 50458 638 20 molluscs molluscs NNP 50458 638 21 , , , 50458 638 22 mussels mussel NNS 50458 638 23 , , , 50458 638 24 oysters oyster NNS 50458 638 25 , , , 50458 638 26 lobsters lobster NNS 50458 638 27 , , , 50458 638 28 and and CC 50458 638 29 snails snail NNS 50458 638 30 . . . 50458 639 1 Lastly lastly RB 50458 639 2 , , , 50458 639 3 moldy moldy JJ 50458 639 4 bread bread NN 50458 639 5 , , , 50458 639 6 spoiled spoiled JJ 50458 639 7 cheese cheese NN 50458 639 8 , , , 50458 639 9 putrid putrid JJ 50458 639 10 water water NN 50458 639 11 , , , 50458 639 12 and and CC 50458 639 13 spoiled spoil VBD 50458 639 14 vegetables vegetable NNS 50458 639 15 themselves -PRON- PRP 50458 639 16 , , , 50458 639 17 are be VBP 50458 639 18 proper proper JJ 50458 639 19 agents agent NNS 50458 639 20 for for IN 50458 639 21 determining determine VBG 50458 639 22 attacks attack NNS 50458 639 23 of of IN 50458 639 24 botulic botulic JJ 50458 639 25 poisoning poisoning NN 50458 639 26 . . . 50458 640 1 We -PRON- PRP 50458 640 2 have have VBP 50458 640 3 seen see VBN 50458 640 4 , , , 50458 640 5 at at IN 50458 640 6 the the DT 50458 640 7 beginning beginning NN 50458 640 8 of of IN 50458 640 9 this this DT 50458 640 10 volume volume NN 50458 640 11 , , , 50458 640 12 that that WDT 50458 640 13 putrid putrid VBP 50458 640 14 meats meat NNS 50458 640 15 contain contain VBP 50458 640 16 ptomaines ptomaine NNS 50458 640 17 , , , 50458 640 18 which which WDT 50458 640 19 are be VBP 50458 640 20 among among IN 50458 640 21 the the DT 50458 640 22 most most RBS 50458 640 23 toxic toxic JJ 50458 640 24 alkaloidal alkaloidal NN 50458 640 25 bases basis NNS 50458 640 26 . . . 50458 641 1 We -PRON- PRP 50458 641 2 have have VBP 50458 641 3 shown show VBN 50458 641 4 that that IN 50458 641 5 Brieger Brieger NNP 50458 641 6 has have VBZ 50458 641 7 isolated isolate VBN 50458 641 8 from from IN 50458 641 9 them -PRON- PRP 50458 641 10 neuridine neuridine JJ 50458 641 11 , , , 50458 641 12 putrescine putrescine NN 50458 641 13 , , , 50458 641 14 muscarine muscarine NNP 50458 641 15 , , , 50458 641 16 and and CC 50458 641 17 guanidine guanidine NN 50458 641 18 ; ; : 50458 641 19 that that IN 50458 641 20 Nencki Nencki NNP 50458 641 21 has have VBZ 50458 641 22 isolated isolate VBN 50458 641 23 hydrocollidine hydrocollidine NN 50458 641 24 ; ; : 50458 641 25 and and CC 50458 641 26 that that DT 50458 641 27 Gautier Gautier NNP 50458 641 28 and and CC 50458 641 29 Etard Etard NNP 50458 641 30 have have VBP 50458 641 31 obtained obtain VBN 50458 641 32 from from IN 50458 641 33 them -PRON- PRP 50458 641 34 parvoline parvoline NN 50458 641 35 -- -- : 50458 641 36 only only RB 50458 641 37 to to TO 50458 641 38 mention mention VB 50458 641 39 a a DT 50458 641 40 few few JJ 50458 641 41 of of IN 50458 641 42 them -PRON- PRP 50458 641 43 . . . 50458 642 1 Lastly lastly RB 50458 642 2 , , , 50458 642 3 there there EX 50458 642 4 may may MD 50458 642 5 develop develop VB 50458 642 6 within within IN 50458 642 7 the the DT 50458 642 8 gastrointestinal gastrointestinal JJ 50458 642 9 tract tract NN 50458 642 10 dangerous dangerous JJ 50458 642 11 putrefactions putrefaction NNS 50458 642 12 , , , 50458 642 13 the the DT 50458 642 14 products product NNS 50458 642 15 of of IN 50458 642 16 which which WDT 50458 642 17 may may MD 50458 642 18 enter enter VB 50458 642 19 the the DT 50458 642 20 veins vein NNS 50458 642 21 and and CC 50458 642 22 arteries artery NNS 50458 642 23 from from IN 50458 642 24 the the DT 50458 642 25 ileum ileum NN 50458 642 26 ( ( -LRB- 50458 642 27 a a DT 50458 642 28 portion portion NN 50458 642 29 of of IN 50458 642 30 the the DT 50458 642 31 small small JJ 50458 642 32 intestine intestine NN 50458 642 33 ) ) -RRB- 50458 642 34 and and CC 50458 642 35 be be VB 50458 642 36 distributed distribute VBN 50458 642 37 throughout throughout IN 50458 642 38 the the DT 50458 642 39 organism organism NN 50458 642 40 . . . 50458 643 1 Although although IN 50458 643 2 such such JJ 50458 643 3 poisonings poisoning NNS 50458 643 4 occur occur VBP 50458 643 5 , , , 50458 643 6 they -PRON- PRP 50458 643 7 do do VBP 50458 643 8 not not RB 50458 643 9 immediately immediately RB 50458 643 10 follow follow VB 50458 643 11 the the DT 50458 643 12 ingestion ingestion NN 50458 643 13 of of IN 50458 643 14 the the DT 50458 643 15 spoiled spoiled JJ 50458 643 16 or or CC 50458 643 17 toxic toxic JJ 50458 643 18 foods food NNS 50458 643 19 , , , 50458 643 20 but but CC 50458 643 21 they -PRON- PRP 50458 643 22 are be VBP 50458 643 23 always always RB 50458 643 24 preceded precede VBN 50458 643 25 by by IN 50458 643 26 a a DT 50458 643 27 period period NN 50458 643 28 of of IN 50458 643 29 incubation incubation NN 50458 643 30 varying vary VBG 50458 643 31 from from IN 50458 643 32 several several JJ 50458 643 33 hours hour NNS 50458 643 34 to to IN 50458 643 35 several several JJ 50458 643 36 days day NNS 50458 643 37 . . . 50458 644 1 These these DT 50458 644 2 alimentary alimentary JJ 50458 644 3 poisonings poisoning NNS 50458 644 4 are be VBP 50458 644 5 recognized recognize VBN 50458 644 6 by by IN 50458 644 7 a a DT 50458 644 8 great great JJ 50458 644 9 physical physical JJ 50458 644 10 depression depression NN 50458 644 11 , , , 50458 644 12 accompanied accompany VBN 50458 644 13 by by IN 50458 644 14 vomiting vomiting NN 50458 644 15 and and CC 50458 644 16 paralysis paralysis NN 50458 644 17 of of IN 50458 644 18 the the DT 50458 644 19 lower low JJR 50458 644 20 extremities extremity NNS 50458 644 21 , , , 50458 644 22 sweats sweat NNS 50458 644 23 , , , 50458 644 24 and and CC 50458 644 25 diarrheas diarrhea NNS 50458 644 26 . . . 50458 645 1 In in IN 50458 645 2 some some DT 50458 645 3 cases case NNS 50458 645 4 there there RB 50458 645 5 occur occur VBP 50458 645 6 cutaneous cutaneous JJ 50458 645 7 eruptions eruption NNS 50458 645 8 ; ; : 50458 645 9 and and CC 50458 645 10 when when WRB 50458 645 11 death death NN 50458 645 12 happens happen VBZ 50458 645 13 , , , 50458 645 14 this this DT 50458 645 15 occurs occur VBZ 50458 645 16 only only RB 50458 645 17 several several JJ 50458 645 18 days day NNS 50458 645 19 later later RB 50458 645 20 , , , 50458 645 21 and and CC 50458 645 22 generally generally RB 50458 645 23 without without IN 50458 645 24 being be VBG 50458 645 25 preceded precede VBN 50458 645 26 by by IN 50458 645 27 any any DT 50458 645 28 great great JJ 50458 645 29 pain pain NN 50458 645 30 . . . 50458 646 1 = = NFP 50458 646 2 Urinary Urinary NNP 50458 646 3 Toxins.=--As Toxins.=--As NNP 50458 646 4 we -PRON- PRP 50458 646 5 have have VBP 50458 646 6 already already RB 50458 646 7 remarked remark VBN 50458 646 8 several several JJ 50458 646 9 times time NNS 50458 646 10 , , , 50458 646 11 it -PRON- PRP 50458 646 12 is be VBZ 50458 646 13 by by IN 50458 646 14 the the DT 50458 646 15 renal renal JJ 50458 646 16 way way NN 50458 646 17 that that WDT 50458 646 18 the the DT 50458 646 19 organism organism NN 50458 646 20 voids void VBZ 50458 646 21 its -PRON- PRP$ 50458 646 22 principal principal JJ 50458 646 23 waste waste NN 50458 646 24 products product NNS 50458 646 25 . . . 50458 647 1 We -PRON- PRP 50458 647 2 have have VBP 50458 647 3 seen see VBN 50458 647 4 also also RB 50458 647 5 that that IN 50458 647 6 it -PRON- PRP 50458 647 7 is be VBZ 50458 647 8 by by IN 50458 647 9 the the DT 50458 647 10 kidneys kidney NNS 50458 647 11 that that IN 50458 647 12 the the DT 50458 647 13 toxins toxin NNS 50458 647 14 are be VBP 50458 647 15 eliminated eliminate VBN 50458 647 16 in in IN 50458 647 17 all all DT 50458 647 18 pathological pathological JJ 50458 647 19 conditions condition NNS 50458 647 20 . . . 50458 648 1 As as IN 50458 648 2 a a DT 50458 648 3 general general JJ 50458 648 4 rule rule NN 50458 648 5 , , , 50458 648 6 the the DT 50458 648 7 urines urine NNS 50458 648 8 are be VBP 50458 648 9 always always RB 50458 648 10 more more RBR 50458 648 11 or or CC 50458 648 12 less less RBR 50458 648 13 toxic toxic JJ 50458 648 14 . . . 50458 649 1 This this DT 50458 649 2 toxicity toxicity NN 50458 649 3 of of IN 50458 649 4 the the DT 50458 649 5 urines urine NNS 50458 649 6 must must MD 50458 649 7 be be VB 50458 649 8 attributed attribute VBN 50458 649 9 in in IN 50458 649 10 the the DT 50458 649 11 first first JJ 50458 649 12 place place NN 50458 649 13 to to IN 50458 649 14 the the DT 50458 649 15 crystallizable crystallizable JJ 50458 649 16 organic organic JJ 50458 649 17 principles principle NNS 50458 649 18 ( ( -LRB- 50458 649 19 ptomaines ptomaine NNS 50458 649 20 and and CC 50458 649 21 leucomaines[75 leucomaines[75 NNP 50458 649 22 ] ] -RRB- 50458 649 23 ) ) -RRB- 50458 649 24 which which WDT 50458 649 25 they -PRON- PRP 50458 649 26 contain contain VBP 50458 649 27 ; ; : 50458 649 28 secondly secondly RB 50458 649 29 , , , 50458 649 30 to to IN 50458 649 31 the the DT 50458 649 32 non non JJ 50458 649 33 - - JJ 50458 649 34 crystallizable[76 crystallizable[76 JJ 50458 649 35 ] ] -RRB- 50458 649 36 extractive extractive JJ 50458 649 37 matters matter NNS 50458 649 38 not not RB 50458 649 39 so so RB 50458 649 40 well well RB 50458 649 41 known known JJ 50458 649 42 ; ; : 50458 649 43 and and CC 50458 649 44 lastly lastly RB 50458 649 45 , , , 50458 649 46 to to IN 50458 649 47 the the DT 50458 649 48 saline saline JJ 50458 649 49 substances substance NNS 50458 649 50 , , , 50458 649 51 among among IN 50458 649 52 which which WDT 50458 649 53 the the DT 50458 649 54 potassium potassium NN 50458 649 55 salts salt NNS 50458 649 56 are be VBP 50458 649 57 the the DT 50458 649 58 most most RBS 50458 649 59 active active JJ 50458 649 60 . . . 50458 650 1 We -PRON- PRP 50458 650 2 find find VBP 50458 650 3 these these DT 50458 650 4 mineral mineral NN 50458 650 5 salts salt NNS 50458 650 6 particularly particularly RB 50458 650 7 abundant abundant JJ 50458 650 8 under under IN 50458 650 9 normal normal JJ 50458 650 10 conditions condition NNS 50458 650 11 in in IN 50458 650 12 the the DT 50458 650 13 urines urine NNS 50458 650 14 of of IN 50458 650 15 the the DT 50458 650 16 herbivora herbivora NN 50458 650 17 . . . 50458 651 1 According accord VBG 50458 651 2 to to IN 50458 651 3 Bouchard Bouchard NNP 50458 651 4 , , , 50458 651 5 0.18 0.18 CD 50458 651 6 Gm Gm NNP 50458 651 7 . . . 50458 652 1 of of IN 50458 652 2 potassium potassium NN 50458 652 3 chloride chloride NN 50458 652 4 are be VBP 50458 652 5 sufficient sufficient JJ 50458 652 6 to to TO 50458 652 7 prove prove VB 50458 652 8 fatal fatal JJ 50458 652 9 to to IN 50458 652 10 1000 1000 CD 50458 652 11 Gm Gm NNP 50458 652 12 . . . 50458 653 1 of of IN 50458 653 2 living living NN 50458 653 3 organism organism NN 50458 653 4 ; ; , 50458 653 5 a a DT 50458 653 6 man man NN 50458 653 7 excretes excrete VBZ 50458 653 8 on on IN 50458 653 9 the the DT 50458 653 10 average average JJ 50458 653 11 2.5 2.5 CD 50458 653 12 Gm Gm NNP 50458 653 13 . . . 50458 654 1 of of IN 50458 654 2 this this DT 50458 654 3 salt salt NN 50458 654 4 , , , 50458 654 5 and and CC 50458 654 6 a a DT 50458 654 7 rabbit rabbit NN 50458 654 8 excretes excrete NNS 50458 654 9 about about IN 50458 654 10 double double PDT 50458 654 11 this this DT 50458 654 12 quantity quantity NN 50458 654 13 , , , 50458 654 14 weight weight NN 50458 654 15 for for IN 50458 654 16 weight weight NN 50458 654 17 . . . 50458 655 1 [ [ -LRB- 50458 655 2 75 75 CD 50458 655 3 ] ] -RRB- 50458 655 4 ADDUCO adduco NN 50458 655 5 : : : 50458 655 6 _ _ NNP 50458 655 7 Arch Arch NNP 50458 655 8 . . . 50458 656 1 Ital Ital NNP 50458 656 2 . . . 50458 657 1 de de NNP 50458 657 2 biolog biolog NNP 50458 657 3 . . . 50458 657 4 _ _ NNP 50458 657 5 , , , 50458 657 6 1891 1891 CD 50458 657 7 . . . 50458 658 1 [ [ -LRB- 50458 658 2 76 76 CD 50458 658 3 ] ] -RRB- 50458 658 4 POUCHET POUCHET NNP 50458 658 5 : : : 50458 658 6 _ _ NNP 50458 658 7 Thèse Thèse NNP 50458 658 8 de de NNP 50458 658 9 Doctorat Doctorat NNP 50458 658 10 en en NNP 50458 658 11 Médecine Médecine NNP 50458 658 12 _ _ NNP 50458 658 13 , , , 50458 658 14 Paris Paris NNP 50458 658 15 , , , 50458 658 16 1878 1878 CD 50458 658 17 . . . 50458 659 1 A a DT 50458 659 2 very very RB 50458 659 3 large large JJ 50458 659 4 number number NN 50458 659 5 of of IN 50458 659 6 hypotheses hypothesis NNS 50458 659 7 have have VBP 50458 659 8 been be VBN 50458 659 9 advanced advance VBN 50458 659 10 regarding regard VBG 50458 659 11 the the DT 50458 659 12 toxicity toxicity NN 50458 659 13 of of IN 50458 659 14 the the DT 50458 659 15 urines urine NNS 50458 659 16 . . . 50458 660 1 Wilson Wilson NNP 50458 660 2 considers consider VBZ 50458 660 3 the the DT 50458 660 4 urea urea NN 50458 660 5 as as IN 50458 660 6 being be VBG 50458 660 7 responsible responsible JJ 50458 660 8 for for IN 50458 660 9 it -PRON- PRP 50458 660 10 ; ; : 50458 660 11 Stadthagen[77 stadthagen[77 ADD 50458 660 12 ] ] -RRB- 50458 660 13 believes believe VBZ 50458 660 14 it -PRON- PRP 50458 660 15 to to TO 50458 660 16 be be VB 50458 660 17 due due IN 50458 660 18 to to IN 50458 660 19 the the DT 50458 660 20 potassium potassium NN 50458 660 21 salts salt NNS 50458 660 22 , , , 50458 660 23 etc etc FW 50458 660 24 . . . 50458 661 1 Bouchard[78 Bouchard[78 NNP 50458 661 2 ] ] -RRB- 50458 661 3 was be VBD 50458 661 4 the the DT 50458 661 5 first first JJ 50458 661 6 to to TO 50458 661 7 recognize recognize VB 50458 661 8 that that IN 50458 661 9 the the DT 50458 661 10 toxicity toxicity NN 50458 661 11 of of IN 50458 661 12 the the DT 50458 661 13 urines urine NNS 50458 661 14 is be VBZ 50458 661 15 due due JJ 50458 661 16 to to IN 50458 661 17 a a DT 50458 661 18 number number NN 50458 661 19 of of IN 50458 661 20 causes cause NNS 50458 661 21 . . . 50458 662 1 We -PRON- PRP 50458 662 2 will will MD 50458 662 3 not not RB 50458 662 4 dwell dwell VB 50458 662 5 further further RB 50458 662 6 on on IN 50458 662 7 these these DT 50458 662 8 active active JJ 50458 662 9 principles principle NNS 50458 662 10 which which WDT 50458 662 11 , , , 50458 662 12 in in IN 50458 662 13 the the DT 50458 662 14 last last JJ 50458 662 15 analysis analysis NN 50458 662 16 , , , 50458 662 17 are be VBP 50458 662 18 no no DT 50458 662 19 other other JJ 50458 662 20 than than IN 50458 662 21 those those DT 50458 662 22 that that DT 50458 662 23 form form VBP 50458 662 24 in in IN 50458 662 25 the the DT 50458 662 26 various various JJ 50458 662 27 portions portion NNS 50458 662 28 of of IN 50458 662 29 the the DT 50458 662 30 organism organism NN 50458 662 31 , , , 50458 662 32 and and CC 50458 662 33 which which WDT 50458 662 34 are be VBP 50458 662 35 eliminated eliminate VBN 50458 662 36 by by IN 50458 662 37 the the DT 50458 662 38 urine urine NN 50458 662 39 . . . 50458 663 1 [ [ -LRB- 50458 663 2 77 77 CD 50458 663 3 ] ] -RRB- 50458 663 4 STADTHAGEN STADTHAGEN NNP 50458 663 5 : : : 50458 663 6 _ _ NNP 50458 663 7 Zeitschr Zeitschr NNP 50458 663 8 . . . 50458 664 1 f. f. NNP 50458 664 2 Klin Klin NNP 50458 664 3 . . . 50458 665 1 Med Med NNP 50458 665 2 . . . 50458 665 3 _ _ NNP 50458 665 4 , , , 50458 665 5 XV XV NNP 50458 665 6 . . . 50458 666 1 [ [ -LRB- 50458 666 2 78 78 CD 50458 666 3 ] ] -RRB- 50458 666 4 BOUCHARD BOUCHARD NNP 50458 666 5 : : : 50458 666 6 _ _ NNP 50458 666 7 Leçons Leçons NNPS 50458 666 8 sur sur FW 50458 666 9 les les FW 50458 666 10 Autointoxications Autointoxications NNP 50458 666 11 _ _ NNP 50458 666 12 . . . 50458 667 1 It -PRON- PRP 50458 667 2 is be VBZ 50458 667 3 self self NN 50458 667 4 - - HYPH 50458 667 5 evident evident JJ 50458 667 6 , , , 50458 667 7 and and CC 50458 667 8 it -PRON- PRP 50458 667 9 has have VBZ 50458 667 10 already already RB 50458 667 11 been be VBN 50458 667 12 shown show VBN 50458 667 13 , , , 50458 667 14 that that IN 50458 667 15 the the DT 50458 667 16 toxicity toxicity NN 50458 667 17 of of IN 50458 667 18 the the DT 50458 667 19 urines urine NNS 50458 667 20 varies vary VBZ 50458 667 21 greatly greatly RB 50458 667 22 according accord VBG 50458 667 23 to to IN 50458 667 24 the the DT 50458 667 25 malady malady JJ 50458 667 26 , , , 50458 667 27 in in IN 50458 667 28 consequence consequence NN 50458 667 29 of of IN 50458 667 30 the the DT 50458 667 31 elimination elimination NN 50458 667 32 of of IN 50458 667 33 toxins toxin NNS 50458 667 34 by by IN 50458 667 35 the the DT 50458 667 36 urines urine NNS 50458 667 37 . . . 50458 668 1 According accord VBG 50458 668 2 to to IN 50458 668 3 Bouchard Bouchard NNP 50458 668 4 , , , 50458 668 5 in in IN 50458 668 6 infectious infectious JJ 50458 668 7 maladies malady NNS 50458 668 8 the the DT 50458 668 9 urines urine NNS 50458 668 10 are be VBP 50458 668 11 twelve twelve CD 50458 668 12 times time NNS 50458 668 13 more more RBR 50458 668 14 highly highly RB 50458 668 15 charged charge VBN 50458 668 16 with with IN 50458 668 17 toxins toxin NNS 50458 668 18 than than IN 50458 668 19 is be VBZ 50458 668 20 blood blood NN 50458 668 21 serum serum NN 50458 668 22 . . . 50458 669 1 Moreover moreover RB 50458 669 2 , , , 50458 669 3 the the DT 50458 669 4 toxicity toxicity NN 50458 669 5 of of IN 50458 669 6 the the DT 50458 669 7 urines urine NNS 50458 669 8 is be VBZ 50458 669 9 considerably considerably RB 50458 669 10 augmented augment VBN 50458 669 11 the the DT 50458 669 12 moment moment NN 50458 669 13 there there EX 50458 669 14 is be VBZ 50458 669 15 the the DT 50458 669 16 least least JJS 50458 669 17 febrile febrile NN 50458 669 18 condition condition NN 50458 669 19 , , , 50458 669 20 no no RB 50458 669 21 matter matter RB 50458 669 22 what what WP 50458 669 23 the the DT 50458 669 24 cause cause NN 50458 669 25 is be VBZ 50458 669 26 . . . 50458 670 1 [ [ -LRB- 50458 670 2 79 79 CD 50458 670 3 ] ] -RRB- 50458 670 4 [ [ -LRB- 50458 670 5 79 79 CD 50458 670 6 ] ] -RRB- 50458 670 7 Regarding regard VBG 50458 670 8 this this DT 50458 670 9 point point NN 50458 670 10 see see VBP 50458 670 11 the the DT 50458 670 12 excellent excellent JJ 50458 670 13 work work NN 50458 670 14 by by IN 50458 670 15 A. a. NN 50458 670 16 CHARRIN CHARRIN NNP 50458 670 17 : : : 50458 670 18 _ _ NNP 50458 670 19 Poisons Poisons NNPS 50458 670 20 de de IN 50458 670 21 l'Organism l'Organism NNP 50458 670 22 _ _ NNP 50458 670 23 . . . 50458 671 1 Masson Masson NNP 50458 671 2 , , , 50458 671 3 publ publ NNS 50458 671 4 . . . 50458 672 1 Even even RB 50458 672 2 in in IN 50458 672 3 the the DT 50458 672 4 normal normal JJ 50458 672 5 condition condition NN 50458 672 6 , , , 50458 672 7 the the DT 50458 672 8 urinary urinary JJ 50458 672 9 toxicity toxicity NN 50458 672 10 varies vary VBZ 50458 672 11 greatly greatly RB 50458 672 12 ; ; : 50458 672 13 and and CC 50458 672 14 this this DT 50458 672 15 is be VBZ 50458 672 16 easily easily RB 50458 672 17 conceived conceive VBN 50458 672 18 since since IN 50458 672 19 the the DT 50458 672 20 physiological physiological JJ 50458 672 21 phenomena phenomenon NNS 50458 672 22 that that WDT 50458 672 23 control control VBP 50458 672 24 this this DT 50458 672 25 secretion secretion NN 50458 672 26 undergo undergo VBP 50458 672 27 incessant incessant NN 50458 672 28 rise rise NN 50458 672 29 and and CC 50458 672 30 fall fall VBP 50458 672 31 . . . 50458 673 1 Thus thus RB 50458 673 2 , , , 50458 673 3 for for IN 50458 673 4 example example NN 50458 673 5 , , , 50458 673 6 the the DT 50458 673 7 urines urine NNS 50458 673 8 eliminated eliminate VBD 50458 673 9 during during IN 50458 673 10 sleep sleep NN 50458 673 11 are be VBP 50458 673 12 less less RBR 50458 673 13 active active JJ 50458 673 14 than than IN 50458 673 15 those those DT 50458 673 16 produced produce VBN 50458 673 17 during during IN 50458 673 18 waking waking NN 50458 673 19 , , , 50458 673 20 because because IN 50458 673 21 during during IN 50458 673 22 sleep sleep NN 50458 673 23 the the DT 50458 673 24 elimination elimination NN 50458 673 25 of of IN 50458 673 26 cellular cellular JJ 50458 673 27 poisons poison NNS 50458 673 28 is be VBZ 50458 673 29 at at IN 50458 673 30 a a DT 50458 673 31 minimum minimum NN 50458 673 32 . . . 50458 674 1 Exercise exercise NN 50458 674 2 , , , 50458 674 3 walking walk VBG 50458 674 4 , , , 50458 674 5 physical physical JJ 50458 674 6 and and CC 50458 674 7 intellectual intellectual JJ 50458 674 8 labor labor NN 50458 674 9 , , , 50458 674 10 exert exert VB 50458 674 11 their -PRON- PRP$ 50458 674 12 portion portion NN 50458 674 13 of of IN 50458 674 14 influence influence NN 50458 674 15 on on IN 50458 674 16 these these DT 50458 674 17 oscillations oscillation NNS 50458 674 18 of of IN 50458 674 19 toxicity toxicity NN 50458 674 20 ; ; : 50458 674 21 and and CC 50458 674 22 this this DT 50458 674 23 variation variation NN 50458 674 24 of of IN 50458 674 25 toxicity toxicity NN 50458 674 26 is be VBZ 50458 674 27 due due JJ 50458 674 28 not not RB 50458 674 29 to to IN 50458 674 30 any any DT 50458 674 31 one one CD 50458 674 32 variation variation NN 50458 674 33 in in IN 50458 674 34 the the DT 50458 674 35 mineral mineral NN 50458 674 36 extractive extractive JJ 50458 674 37 matters matter NNS 50458 674 38 , , , 50458 674 39 but but CC 50458 674 40 rather rather RB 50458 674 41 more more RBR 50458 674 42 or or CC 50458 674 43 less less JJR 50458 674 44 to to IN 50458 674 45 the the DT 50458 674 46 organic organic JJ 50458 674 47 toxic toxic JJ 50458 674 48 products product NNS 50458 674 49 . . . 50458 675 1 We -PRON- PRP 50458 675 2 will will MD 50458 675 3 not not RB 50458 675 4 dwell dwell VB 50458 675 5 further further RB 50458 675 6 on on IN 50458 675 7 this this DT 50458 675 8 subject subject NN 50458 675 9 , , , 50458 675 10 but but CC 50458 675 11 will will MD 50458 675 12 simply simply RB 50458 675 13 refer refer VB 50458 675 14 to to IN 50458 675 15 the the DT 50458 675 16 work work NN 50458 675 17 by by IN 50458 675 18 Charrin Charrin NNP 50458 675 19 , , , 50458 675 20 already already RB 50458 675 21 mentioned mention VBN 50458 675 22 , , , 50458 675 23 for for IN 50458 675 24 all all DT 50458 675 25 supplementary supplementary JJ 50458 675 26 details detail NNS 50458 675 27 . . . 50458 676 1 = = NFP 50458 676 2 Autointoxications.=[80]--The autointoxications.=[80]--the NN 50458 676 3 cells cell NNS 50458 676 4 of of IN 50458 676 5 the the DT 50458 676 6 organism organism NN 50458 676 7 having have VBG 50458 676 8 , , , 50458 676 9 as as IN 50458 676 10 a a DT 50458 676 11 whole whole NN 50458 676 12 , , , 50458 676 13 a a DT 50458 676 14 life life NN 50458 676 15 very very RB 50458 676 16 much much RB 50458 676 17 like like IN 50458 676 18 that that DT 50458 676 19 of of IN 50458 676 20 the the DT 50458 676 21 microbes microbe NNS 50458 676 22 , , , 50458 676 23 it -PRON- PRP 50458 676 24 is be VBZ 50458 676 25 quite quite RB 50458 676 26 natural natural JJ 50458 676 27 that that IN 50458 676 28 among among IN 50458 676 29 the the DT 50458 676 30 excreted excreted JJ 50458 676 31 products product NNS 50458 676 32 of of IN 50458 676 33 the the DT 50458 676 34 living live VBG 50458 676 35 tissues tissue NNS 50458 676 36 there there EX 50458 676 37 should should MD 50458 676 38 be be VB 50458 676 39 found find VBN 50458 676 40 the the DT 50458 676 41 same same JJ 50458 676 42 substances substance NNS 50458 676 43 formed form VBN 50458 676 44 as as IN 50458 676 45 a a DT 50458 676 46 result result NN 50458 676 47 of of IN 50458 676 48 the the DT 50458 676 49 anaerobic anaerobic JJ 50458 676 50 fermentation fermentation NN 50458 676 51 of of IN 50458 676 52 albuminoids albuminoid NNS 50458 676 53 . . . 50458 677 1 Experiment experiment NN 50458 677 2 has have VBZ 50458 677 3 demonstrated demonstrate VBN 50458 677 4 that that IN 50458 677 5 this this DT 50458 677 6 is be VBZ 50458 677 7 so so RB 50458 677 8 , , , 50458 677 9 and and CC 50458 677 10 Armand Armand NNP 50458 677 11 Gautier Gautier NNP 50458 677 12 has have VBZ 50458 677 13 irrefutably irrefutably RB 50458 677 14 proven prove VBN 50458 677 15 the the DT 50458 677 16 existence existence NN 50458 677 17 of of IN 50458 677 18 these these DT 50458 677 19 principles principle NNS 50458 677 20 . . . 50458 678 1 [ [ -LRB- 50458 678 2 81 81 CD 50458 678 3 ] ] -RRB- 50458 678 4 Bouchard Bouchard NNP 50458 678 5 was be VBD 50458 678 6 the the DT 50458 678 7 first first JJ 50458 678 8 to to TO 50458 678 9 demonstrate demonstrate VB 50458 678 10 the the DT 50458 678 11 toxic toxic JJ 50458 678 12 nature nature NN 50458 678 13 of of IN 50458 678 14 muscle muscle NN 50458 678 15 extract,[82 extract,[82 NNP 50458 678 16 ] ] -RRB- 50458 678 17 and and CC 50458 678 18 Roger[83 roger[83 CD 50458 678 19 ] ] -RRB- 50458 678 20 established establish VBD 50458 678 21 the the DT 50458 678 22 fact fact NN 50458 678 23 that that IN 50458 678 24 the the DT 50458 678 25 toxicity toxicity NN 50458 678 26 of of IN 50458 678 27 this this DT 50458 678 28 extract extract NN 50458 678 29 is be VBZ 50458 678 30 due due JJ 50458 678 31 to to IN 50458 678 32 ferment ferment NN 50458 678 33 - - HYPH 50458 678 34 toxins toxin NNS 50458 678 35 ; ; : 50458 678 36 it -PRON- PRP 50458 678 37 has have VBZ 50458 678 38 since since IN 50458 678 39 been be VBN 50458 678 40 recognized recognize VBN 50458 678 41 that that IN 50458 678 42 after after IN 50458 678 43 death death NN 50458 678 44 these these DT 50458 678 45 toxins toxin NNS 50458 678 46 accumulate accumulate VBP 50458 678 47 in in IN 50458 678 48 the the DT 50458 678 49 muscles muscle NNS 50458 678 50 . . . 50458 679 1 [ [ -LRB- 50458 679 2 80 80 CD 50458 679 3 ] ] -RRB- 50458 679 4 CH CH NNP 50458 679 5 . . . 50458 680 1 BOUCHARD BOUCHARD NNP 50458 680 2 : : : 50458 680 3 _ _ NNP 50458 680 4 Des Des NNP 50458 680 5 Autointoxications Autointoxications NNP 50458 680 6 _ _ NNP 50458 680 7 . . . 50458 681 1 Paris Paris NNP 50458 681 2 , , , 50458 681 3 1887 1887 CD 50458 681 4 . . . 50458 682 1 [ [ -LRB- 50458 682 2 81 81 CD 50458 682 3 ] ] -RRB- 50458 682 4 _ _ NNP 50458 682 5 Bull Bull NNP 50458 682 6 . . . 50458 683 1 Acad Acad NNP 50458 683 2 , , , 50458 683 3 de de NNP 50458 683 4 Médecine Médecine NNP 50458 683 5 _ _ NNP 50458 683 6 ( ( -LRB- 50458 683 7 2 2 CD 50458 683 8 ) ) -RRB- 50458 683 9 , , , 50458 683 10 X x NN 50458 683 11 , , , 50458 683 12 p. p. NN 50458 683 13 947 947 CD 50458 683 14 , , , 50458 683 15 and and CC 50458 683 16 XX XX NNP 50458 683 17 , , , 50458 683 18 p. p. NN 50458 683 19 115 115 CD 50458 683 20 . . . 50458 684 1 [ [ -LRB- 50458 684 2 82 82 CD 50458 684 3 ] ] -RRB- 50458 684 4 BOUCHARD BOUCHARD NNP 50458 684 5 : : : 50458 684 6 _ _ NNP 50458 684 7 Leçons Leçons NNPS 50458 684 8 sur sur FW 50458 684 9 les les FW 50458 684 10 Autointoxications Autointoxications NNP 50458 684 11 _ _ NNP 50458 684 12 , , , 50458 684 13 Paris Paris NNP 50458 684 14 , , , 50458 684 15 1887 1887 CD 50458 684 16 . . . 50458 685 1 [ [ -LRB- 50458 685 2 83 83 CD 50458 685 3 ] ] -RRB- 50458 685 4 ROGER ROGER NNP 50458 685 5 : : : 50458 685 6 Toxicité Toxicité NNP 50458 685 7 des des FW 50458 685 8 Extraits Extraits NNP 50458 685 9 des des NNP 50458 685 10 Tissus Tissus NNP 50458 685 11 Normaux Normaux NNP 50458 685 12 . . . 50458 686 1 _ _ NNP 50458 686 2 Soc Soc NNP 50458 686 3 . . . 50458 687 1 de de NNP 50458 687 2 Biolog Biolog NNP 50458 687 3 . . . 50458 687 4 _ _ NNP 50458 687 5 , , , 50458 687 6 1891 1891 CD 50458 687 7 , , , 50458 687 8 p. p. NN 50458 687 9 728 728 CD 50458 687 10 . . . 50458 688 1 The the DT 50458 688 2 extract extract NN 50458 688 3 of of IN 50458 688 4 kidney kidney NN 50458 688 5 made make VBD 50458 688 6 rapidly rapidly RB 50458 688 7 by by IN 50458 688 8 cold cold JJ 50458 688 9 process process NN 50458 688 10 by by IN 50458 688 11 triturating triturate VBG 50458 688 12 the the DT 50458 688 13 washed washed JJ 50458 688 14 kidney kidney NN 50458 688 15 with with IN 50458 688 16 glycerin glycerin NNP 50458 688 17 , , , 50458 688 18 and and CC 50458 688 19 precipitating precipitate VBG 50458 688 20 the the DT 50458 688 21 glycerinic glycerinic JJ 50458 688 22 solution solution NN 50458 688 23 with with IN 50458 688 24 alcohol alcohol NN 50458 688 25 , , , 50458 688 26 contains contain VBZ 50458 688 27 toxic toxic JJ 50458 688 28 ferments ferment NNS 50458 688 29 to to TO 50458 688 30 which which WDT 50458 688 31 the the DT 50458 688 32 name name NN 50458 688 33 " " `` 50458 688 34 _ _ NNP 50458 688 35 hystozymes hystozymes NNP 50458 688 36 _ _ NNP 50458 688 37 " " `` 50458 688 38 has have VBZ 50458 688 39 been be VBN 50458 688 40 given give VBN 50458 688 41 . . . 50458 689 1 [ [ -LRB- 50458 689 2 84 84 CD 50458 689 3 ] ] -RRB- 50458 689 4 These these DT 50458 689 5 ferments ferment NNS 50458 689 6 split split VBD 50458 689 7 up up RP 50458 689 8 hippuric hippuric NN 50458 689 9 acid acid NN 50458 689 10 into into IN 50458 689 11 benzoic benzoic JJ 50458 689 12 acid acid NN 50458 689 13 and and CC 50458 689 14 glycocoll glycocoll NN 50458 689 15 . . . 50458 690 1 Lépine Lépine NNP 50458 690 2 has have VBZ 50458 690 3 likewise likewise RB 50458 690 4 discovered discover VBN 50458 690 5 in in IN 50458 690 6 the the DT 50458 690 7 kidney kidney NN 50458 690 8 a a DT 50458 690 9 very very RB 50458 690 10 toxic toxic JJ 50458 690 11 pyrogenic pyrogenic JJ 50458 690 12 substance substance NN 50458 690 13 . . . 50458 691 1 [ [ -LRB- 50458 691 2 85 85 CD 50458 691 3 ] ] -RRB- 50458 691 4 Roger Roger NNP 50458 691 5 has have VBZ 50458 691 6 given give VBN 50458 691 7 us -PRON- PRP 50458 691 8 evidence evidence NN 50458 691 9 of of IN 50458 691 10 the the DT 50458 691 11 toxic toxic JJ 50458 691 12 properties property NNS 50458 691 13 of of IN 50458 691 14 the the DT 50458 691 15 liver liver NN 50458 691 16 , , , 50458 691 17 washed wash VBD 50458 691 18 and and CC 50458 691 19 pulped pulp VBD 50458 691 20 , , , 50458 691 21 and and CC 50458 691 22 then then RB 50458 691 23 sterilized sterilize VBN 50458 691 24 by by IN 50458 691 25 filtration filtration NN 50458 691 26 through through IN 50458 691 27 a a DT 50458 691 28 porous porous JJ 50458 691 29 diaphragm diaphragm NN 50458 691 30 . . . 50458 692 1 This this DT 50458 692 2 scientist scientist NN 50458 692 3 has have VBZ 50458 692 4 shown show VBN 50458 692 5 that that IN 50458 692 6 the the DT 50458 692 7 toxic toxic JJ 50458 692 8 properties property NNS 50458 692 9 are be VBP 50458 692 10 due due JJ 50458 692 11 to to IN 50458 692 12 albuminoids albuminoid NNS 50458 692 13 , , , 50458 692 14 which which WDT 50458 692 15 lose lose VBP 50458 692 16 their -PRON- PRP$ 50458 692 17 activity activity NN 50458 692 18 when when WRB 50458 692 19 heated heat VBN 50458 692 20 to to IN 50458 692 21 100 100 CD 50458 692 22 ° ° NNS 50458 692 23 C C NNP 50458 692 24 . . . 50458 693 1 [ [ -LRB- 50458 693 2 86 86 CD 50458 693 3 ] ] -RRB- 50458 693 4 [ [ -LRB- 50458 693 5 84 84 CD 50458 693 6 ] ] -RRB- 50458 693 7 It -PRON- PRP 50458 693 8 is be VBZ 50458 693 9 well well JJ 50458 693 10 to to TO 50458 693 11 recall recall VB 50458 693 12 here here RB 50458 693 13 that that IN 50458 693 14 the the DT 50458 693 15 kidneys kidney NNS 50458 693 16 contain contain VBP 50458 693 17 both both CC 50458 693 18 reducing reduce VBG 50458 693 19 and and CC 50458 693 20 oxidizing oxidize VBG 50458 693 21 ferments ferment NNS 50458 693 22 , , , 50458 693 23 as as IN 50458 693 24 has have VBZ 50458 693 25 been be VBN 50458 693 26 demonstrated demonstrate VBN 50458 693 27 by by IN 50458 693 28 de de NNP 50458 693 29 Rey Rey NNP 50458 693 30 - - HYPH 50458 693 31 Pailhade Pailhade NNP 50458 693 32 , , , 50458 693 33 and and CC 50458 693 34 later later RB 50458 693 35 by by IN 50458 693 36 Abelous Abelous NNP 50458 693 37 and and CC 50458 693 38 Gérard Gérard NNP 50458 693 39 . . . 50458 694 1 [ [ -LRB- 50458 694 2 85 85 CD 50458 694 3 ] ] -RRB- 50458 694 4 LÉPINE LÉPINE NNP 50458 694 5 : : : 50458 694 6 _ _ NNP 50458 694 7 Compt Compt NNP 50458 694 8 . . . 50458 695 1 rend rend VB 50458 695 2 . . . 50458 696 1 de de NNP 50458 696 2 l'Acad l'Acad NNP 50458 696 3 . . . 50458 697 1 des des NNP 50458 697 2 Sciences Sciences NNPS 50458 697 3 _ _ NNP 50458 697 4 , , , 50458 697 5 May May NNP 50458 697 6 13 13 CD 50458 697 7 , , , 50458 697 8 1889 1889 CD 50458 697 9 ; ; : 50458 697 10 _ _ NNP 50458 697 11 Soc Soc NNP 50458 697 12 . . . 50458 698 1 de de NNP 50458 698 2 Biol Biol NNP 50458 698 3 . . . 50458 698 4 _ _ NNP 50458 698 5 , , , 50458 698 6 1891 1891 CD 50458 698 7 , , , 50458 698 8 p. p. NN 50458 698 9 724 724 CD 50458 698 10 . . . 50458 699 1 [ [ -LRB- 50458 699 2 86 86 CD 50458 699 3 ] ] -RRB- 50458 699 4 ROGER ROGER NNP 50458 699 5 : : : 50458 699 6 _ _ NNP 50458 699 7 Compt Compt NNP 50458 699 8 . . . 50458 700 1 rend rend VB 50458 700 2 . . . 50458 701 1 Soc Soc NNP 50458 701 2 . . . 50458 702 1 Biol Biol NNP 50458 702 2 . . . 50458 702 3 _ _ NNP 50458 702 4 , , , 50458 702 5 1891 1891 CD 50458 702 6 , , , 50458 702 7 p. p. NN 50458 702 8 727 727 CD 50458 702 9 . . . 50458 703 1 It -PRON- PRP 50458 703 2 must must MD 50458 703 3 be be VB 50458 703 4 remarked remark VBN 50458 703 5 that that IN 50458 703 6 the the DT 50458 703 7 organs organ NNS 50458 703 8 we -PRON- PRP 50458 703 9 have have VBP 50458 703 10 studied study VBN 50458 703 11 are be VBP 50458 703 12 essentially essentially RB 50458 703 13 reducers reducer NNS 50458 703 14 , , , 50458 703 15 and and CC 50458 703 16 that that IN 50458 703 17 the the DT 50458 703 18 more more RBR 50458 703 19 powerful powerful JJ 50458 703 20 reducers reducer NNS 50458 703 21 yield yield VBP 50458 703 22 the the DT 50458 703 23 most most RBS 50458 703 24 toxic toxic JJ 50458 703 25 extracts extract NNS 50458 703 26 . . . 50458 704 1 We -PRON- PRP 50458 704 2 find find VBP 50458 704 3 here here RB 50458 704 4 a a DT 50458 704 5 confirmation confirmation NN 50458 704 6 of of IN 50458 704 7 Armand Armand NNP 50458 704 8 Gautier Gautier NNP 50458 704 9 's 's POS 50458 704 10 views view NNS 50458 704 11 regarding regard VBG 50458 704 12 the the DT 50458 704 13 anaerobic anaerobic JJ 50458 704 14 origin origin NN 50458 704 15 of of IN 50458 704 16 the the DT 50458 704 17 toxic toxic JJ 50458 704 18 substances substance NNS 50458 704 19 formed form VBN 50458 704 20 within within IN 50458 704 21 the the DT 50458 704 22 organism organism NN 50458 704 23 . . . 50458 705 1 [ [ -LRB- 50458 705 2 87 87 CD 50458 705 3 ] ] -RRB- 50458 705 4 [ [ -LRB- 50458 705 5 87 87 CD 50458 705 6 ] ] -RRB- 50458 705 7 POZZI POZZI NNP 50458 705 8 - - HYPH 50458 705 9 ESCOT ESCOT NNP 50458 705 10 : : : 50458 705 11 _ _ NNP 50458 705 12 Compt Compt NNP 50458 705 13 . . . 50458 706 1 rend rend VB 50458 706 2 . . . 50458 707 1 de de NNP 50458 707 2 l'Acad l'Acad NNP 50458 707 3 . . . 50458 708 1 de de NNP 50458 708 2 Médecine Médecine NNP 50458 708 3 _ _ NNP 50458 708 4 ( ( -LRB- 50458 708 5 3 3 CD 50458 708 6 ) ) -RRB- 50458 708 7 , , , 50458 708 8 XLVII XLVII NNP 50458 708 9 , , , 50458 708 10 p. p. NN 50458 708 11 400 400 CD 50458 708 12 . . . 50458 709 1 See see VB 50458 709 2 also also RB 50458 709 3 POZZI POZZI NNP 50458 709 4 - - HYPH 50458 709 5 ESCOT ESCOT NNP 50458 709 6 : : : 50458 709 7 _ _ NNP 50458 709 8 Etat Etat NNP 50458 709 9 actuel actuel NNP 50458 709 10 de de FW 50458 709 11 nos nos NNP 50458 709 12 Connaissances Connaissances NNP 50458 709 13 sur sur FW 50458 709 14 les les FW 50458 709 15 Oxydases Oxydases NNP 50458 709 16 et et FW 50458 709 17 les les FW 50458 709 18 Réductases Réductases NNP 50458 709 19 _ _ NNP 50458 709 20 . . . 50458 710 1 Dunod dunod NN 50458 710 2 , , , 50458 710 3 publ publ NNS 50458 710 4 . . . 50458 710 5 , , , 50458 710 6 Paris Paris NNP 50458 710 7 . . . 50458 711 1 1902 1902 CD 50458 711 2 . . . 50458 712 1 Blood blood NN 50458 712 2 serum serum NN 50458 712 3 precipitated precipitate VBN 50458 712 4 by by IN 50458 712 5 alcohol alcohol NN 50458 712 6 affords afford NNS 50458 712 7 products product NNS 50458 712 8 which which WDT 50458 712 9 possess possess VBP 50458 712 10 very very RB 50458 712 11 marked mark VBN 50458 712 12 toxic toxic JJ 50458 712 13 power power NN 50458 712 14 . . . 50458 713 1 It -PRON- PRP 50458 713 2 would would MD 50458 713 3 appear appear VB 50458 713 4 that that IN 50458 713 5 the the DT 50458 713 6 toxic toxic JJ 50458 713 7 products product NNS 50458 713 8 we -PRON- PRP 50458 713 9 speak speak VBP 50458 713 10 of of IN 50458 713 11 here here RB 50458 713 12 are be VBP 50458 713 13 thermogenic thermogenic JJ 50458 713 14 diastatic diastatic JJ 50458 713 15 substances substance NNS 50458 713 16 derived derive VBN 50458 713 17 from from IN 50458 713 18 the the DT 50458 713 19 white white JJ 50458 713 20 blood blood NN 50458 713 21 corpuscles corpuscle NNS 50458 713 22 . . . 50458 714 1 In in IN 50458 714 2 certain certain JJ 50458 714 3 diseases disease NNS 50458 714 4 the the DT 50458 714 5 blood blood NN 50458 714 6 serum serum NN 50458 714 7 may may MD 50458 714 8 acquire acquire VB 50458 714 9 a a DT 50458 714 10 high high JJ 50458 714 11 degree degree NN 50458 714 12 of of IN 50458 714 13 toxicity toxicity NN 50458 714 14 . . . 50458 715 1 We -PRON- PRP 50458 715 2 will will MD 50458 715 3 recur recur VB 50458 715 4 again again RB 50458 715 5 presently presently RB 50458 715 6 to to IN 50458 715 7 this this DT 50458 715 8 property property NN 50458 715 9 as as IN 50458 715 10 a a DT 50458 715 11 normal normal JJ 50458 715 12 characteristic characteristic NN 50458 715 13 of of IN 50458 715 14 the the DT 50458 715 15 blood blood NN 50458 715 16 of of IN 50458 715 17 various various JJ 50458 715 18 animal animal NN 50458 715 19 species specie NNS 50458 715 20 , , , 50458 715 21 and and CC 50458 715 22 will will MD 50458 715 23 study study VB 50458 715 24 it -PRON- PRP 50458 715 25 in in IN 50458 715 26 greater great JJR 50458 715 27 detail detail NN 50458 715 28 in in IN 50458 715 29 a a DT 50458 715 30 future future JJ 50458 715 31 volume volume NN 50458 715 32 of of IN 50458 715 33 this this DT 50458 715 34 collection collection NN 50458 715 35 , , , 50458 715 36 devoted devote VBN 50458 715 37 to to IN 50458 715 38 the the DT 50458 715 39 immunizing immunize VBG 50458 715 40 active active JJ 50458 715 41 principles principle NNS 50458 715 42 . . . 50458 716 1 = = NFP 50458 716 2 Glandular Glandular NNP 50458 716 3 Secretions.=--On Secretions.=--On NNS 50458 716 4 studying study VBG 50458 716 5 the the DT 50458 716 6 venoms venom NNS 50458 716 7 we -PRON- PRP 50458 716 8 will will MD 50458 716 9 see see VB 50458 716 10 that that IN 50458 716 11 a a DT 50458 716 12 certain certain JJ 50458 716 13 number number NN 50458 716 14 of of IN 50458 716 15 these these DT 50458 716 16 products product NNS 50458 716 17 are be VBP 50458 716 18 the the DT 50458 716 19 result result NN 50458 716 20 of of IN 50458 716 21 glandular glandular JJ 50458 716 22 secretion secretion NN 50458 716 23 . . . 50458 717 1 This this DT 50458 717 2 is be VBZ 50458 717 3 a a DT 50458 717 4 general general JJ 50458 717 5 property property NN 50458 717 6 of of IN 50458 717 7 the the DT 50458 717 8 glands gland NNS 50458 717 9 ; ; : 50458 717 10 and and CC 50458 717 11 it -PRON- PRP 50458 717 12 was be VBD 50458 717 13 Brown Brown NNP 50458 717 14 - - HYPH 50458 717 15 Sequard Sequard NNP 50458 717 16 who who WP 50458 717 17 first first RB 50458 717 18 drew draw VBD 50458 717 19 attention attention NN 50458 717 20 to to IN 50458 717 21 the the DT 50458 717 22 rôle rôle NN 50458 717 23 played play VBN 50458 717 24 by by IN 50458 717 25 these these DT 50458 717 26 glands gland NNS 50458 717 27 , , , 50458 717 28 and and CC 50458 717 29 to to IN 50458 717 30 the the DT 50458 717 31 importance importance NN 50458 717 32 of of IN 50458 717 33 the the DT 50458 717 34 products product NNS 50458 717 35 that that WDT 50458 717 36 they -PRON- PRP 50458 717 37 throw throw VBP 50458 717 38 into into IN 50458 717 39 the the DT 50458 717 40 blood blood NN 50458 717 41 . . . 50458 718 1 [ [ -LRB- 50458 718 2 88 88 CD 50458 718 3 ] ] -RRB- 50458 718 4 [ [ -LRB- 50458 718 5 88 88 CD 50458 718 6 ] ] -RRB- 50458 718 7 _ _ NNP 50458 718 8 Compt Compt NNP 50458 718 9 . . . 50458 719 1 rend rend VB 50458 719 2 . . . 50458 720 1 de de NNP 50458 720 2 l'Acad l'Acad NNP 50458 720 3 . . . 50458 721 1 des des NNP 50458 721 2 Sciences Sciences NNPS 50458 721 3 _ _ NNP 50458 721 4 , , , 50458 721 5 CXIV CXIV NNP 50458 721 6 , , , 50458 721 7 pp pp NNP 50458 721 8 . . . 50458 722 1 1237 1237 CD 50458 722 2 , , , 50458 722 3 1318 1318 CD 50458 722 4 , , , 50458 722 5 1399 1399 CD 50458 722 6 , , , 50458 722 7 and and CC 50458 722 8 1534 1534 CD 50458 722 9 ; ; : 50458 722 10 CXV CXV NNP 50458 722 11 , , , 50458 722 12 p. p. NN 50458 722 13 375 375 CD 50458 722 14 ; ; : 50458 722 15 and and CC 50458 722 16 CXVI CXVI NNP 50458 722 17 , , , 50458 722 18 p. p. NN 50458 722 19 856 856 CD 50458 722 20 . . . 50458 723 1 P. P. NNP 50458 723 2 Noel Noel NNP 50458 723 3 showed show VBD 50458 723 4 later later RB 50458 723 5 that that IN 50458 723 6 the the DT 50458 723 7 testicular testicular JJ 50458 723 8 juice juice NN 50458 723 9 possesses possess VBZ 50458 723 10 a a DT 50458 723 11 high high JJ 50458 723 12 degree degree NN 50458 723 13 of of IN 50458 723 14 activity activity NN 50458 723 15 , , , 50458 723 16 which which WDT 50458 723 17 he -PRON- PRP 50458 723 18 attributed attribute VBD 50458 723 19 to to IN 50458 723 20 an an DT 50458 723 21 oxidizing oxidizing JJ 50458 723 22 ferment ferment NN 50458 723 23 , , , 50458 723 24 and and CC 50458 723 25 which which WDT 50458 723 26 we -PRON- PRP 50458 723 27 have have VBP 50458 723 28 already already RB 50458 723 29 mentioned mention VBN 50458 723 30 , , , 50458 723 31 _ _ NNP 50458 723 32 spermine spermine NN 50458 723 33 _ _ NNP 50458 723 34 . . . 50458 724 1 The the DT 50458 724 2 greater great JJR 50458 724 3 number number NN 50458 724 4 of of IN 50458 724 5 the the DT 50458 724 6 other other JJ 50458 724 7 glands gland NNS 50458 724 8 contain contain VBP 50458 724 9 proteid proteid NN 50458 724 10 matters matter NNS 50458 724 11 and and CC 50458 724 12 various various JJ 50458 724 13 peptones peptone NNS 50458 724 14 , , , 50458 724 15 more more RBR 50458 724 16 or or CC 50458 724 17 less less RBR 50458 724 18 toxic toxic JJ 50458 724 19 , , , 50458 724 20 with with IN 50458 724 21 amides amide NNS 50458 724 22 and and CC 50458 724 23 alkaloids alkaloid NNS 50458 724 24 . . . 50458 725 1 Particular particular JJ 50458 725 2 mention mention NN 50458 725 3 must must MD 50458 725 4 be be VB 50458 725 5 made make VBN 50458 725 6 of of IN 50458 725 7 the the DT 50458 725 8 thyroid thyroid NNP 50458 725 9 gland gland NNP 50458 725 10 , , , 50458 725 11 the the DT 50458 725 12 secretions secretion NNS 50458 725 13 of of IN 50458 725 14 which which WDT 50458 725 15 exercise exercise VBP 50458 725 16 a a DT 50458 725 17 powerful powerful JJ 50458 725 18 action action NN 50458 725 19 on on IN 50458 725 20 the the DT 50458 725 21 nervous nervous JJ 50458 725 22 centers center NNS 50458 725 23 and and CC 50458 725 24 on on IN 50458 725 25 nutrition nutrition NN 50458 725 26 . . . 50458 726 1 [ [ -LRB- 50458 726 2 89 89 CD 50458 726 3 ] ] -RRB- 50458 726 4 It -PRON- PRP 50458 726 5 appears appear VBZ 50458 726 6 reasonable reasonable JJ 50458 726 7 to to TO 50458 726 8 attribute attribute VB 50458 726 9 to to IN 50458 726 10 the the DT 50458 726 11 secretions secretion NNS 50458 726 12 of of IN 50458 726 13 this this DT 50458 726 14 gland gland NN 50458 726 15 a a DT 50458 726 16 very very RB 50458 726 17 powerful powerful JJ 50458 726 18 antitoxic antitoxic JJ 50458 726 19 action action NN 50458 726 20 , , , 50458 726 21 and and CC 50458 726 22 the the DT 50458 726 23 first first JJ 50458 726 24 proof proof NN 50458 726 25 of of IN 50458 726 26 this this DT 50458 726 27 fact fact NN 50458 726 28 is be VBZ 50458 726 29 that that IN 50458 726 30 the the DT 50458 726 31 organisms organism NNS 50458 726 32 deprived deprive VBN 50458 726 33 of of IN 50458 726 34 this this DT 50458 726 35 gland gland NN 50458 726 36 become become VBP 50458 726 37 the the DT 50458 726 38 seat seat NN 50458 726 39 of of IN 50458 726 40 serious serious JJ 50458 726 41 derangements derangement NNS 50458 726 42 ; ; : 50458 726 43 the the DT 50458 726 44 urines urine NNS 50458 726 45 of of IN 50458 726 46 such such JJ 50458 726 47 organisms organism NNS 50458 726 48 become become VBP 50458 726 49 particularly particularly RB 50458 726 50 toxic toxic JJ 50458 726 51 , , , 50458 726 52 while while IN 50458 726 53 , , , 50458 726 54 on on IN 50458 726 55 the the DT 50458 726 56 other other JJ 50458 726 57 hand hand NN 50458 726 58 , , , 50458 726 59 the the DT 50458 726 60 hypodermic hypodermic JJ 50458 726 61 injections injection NNS 50458 726 62 of of IN 50458 726 63 the the DT 50458 726 64 aqueous aqueous JJ 50458 726 65 extract extract NN 50458 726 66 of of IN 50458 726 67 the the DT 50458 726 68 gland gland NN 50458 726 69 , , , 50458 726 70 when when WRB 50458 726 71 the the DT 50458 726 72 derangements derangement NNS 50458 726 73 spoken speak VBN 50458 726 74 of of IN 50458 726 75 exist exist NN 50458 726 76 , , , 50458 726 77 cause cause VB 50458 726 78 the the DT 50458 726 79 immediate immediate JJ 50458 726 80 disappearance disappearance NN 50458 726 81 of of IN 50458 726 82 the the DT 50458 726 83 derangements derangement NNS 50458 726 84 caused cause VBN 50458 726 85 by by IN 50458 726 86 the the DT 50458 726 87 excision excision NN 50458 726 88 of of IN 50458 726 89 the the DT 50458 726 90 gland gland NN 50458 726 91 . . . 50458 727 1 [ [ -LRB- 50458 727 2 90 90 CD 50458 727 3 ] ] -RRB- 50458 727 4 [ [ -LRB- 50458 727 5 89 89 CD 50458 727 6 ] ] -RRB- 50458 727 7 LAULANIÉ LAULANIÉ NNP 50458 727 8 : : : 50458 727 9 _ _ NNP 50458 727 10 Compt Compt NNP 50458 727 11 . . . 50458 728 1 rend rend VB 50458 728 2 . . . 50458 729 1 Soc Soc NNP 50458 729 2 . . . 50458 730 1 de de NNP 50458 730 2 Biol Biol NNP 50458 730 3 . . . 50458 730 4 _ _ NNP 50458 730 5 , , , 50458 730 6 1894 1894 CD 50458 730 7 , , , 50458 730 8 p. p. NN 50458 730 9 187 187 CD 50458 730 10 . . . 50458 731 1 [ [ -LRB- 50458 731 2 90 90 CD 50458 731 3 ] ] -RRB- 50458 731 4 GLEY GLEY NNP 50458 731 5 : : : 50458 731 6 _ _ NNP 50458 731 7 Compt Compt NNP 50458 731 8 . . . 50458 732 1 rend rend VB 50458 732 2 . . . 50458 733 1 Soc Soc NNP 50458 733 2 . . . 50458 734 1 de de NNP 50458 734 2 Biol Biol NNP 50458 734 3 . . . 50458 734 4 _ _ NNP 50458 734 5 , , , 50458 734 6 1891 1891 CD 50458 734 7 , , , 50458 734 8 p. p. NN 50458 734 9 250 250 CD 50458 734 10 . . . 50458 735 1 Attempts attempt NNS 50458 735 2 have have VBP 50458 735 3 been be VBN 50458 735 4 made make VBN 50458 735 5 to to TO 50458 735 6 isolate isolate VB 50458 735 7 the the DT 50458 735 8 active active JJ 50458 735 9 principle principle NN 50458 735 10 of of IN 50458 735 11 the the DT 50458 735 12 glands gland NNS 50458 735 13 . . . 50458 736 1 Notkine Notkine NNP 50458 736 2 isolated isolate VBD 50458 736 3 a a DT 50458 736 4 _ _ NNP 50458 736 5 tyroproteid_,[91 tyroproteid_,[91 NN 50458 736 6 ] ] -RRB- 50458 736 7 which which WDT 50458 736 8 is be VBZ 50458 736 9 not not RB 50458 736 10 sensibly sensibly RB 50458 736 11 toxic toxic JJ 50458 736 12 to to IN 50458 736 13 animals animal NNS 50458 736 14 who who WP 50458 736 15 still still RB 50458 736 16 retain retain VBP 50458 736 17 the the DT 50458 736 18 gland gland NN 50458 736 19 , , , 50458 736 20 but but CC 50458 736 21 which which WDT 50458 736 22 becomes become VBZ 50458 736 23 toxic toxic JJ 50458 736 24 when when WRB 50458 736 25 the the DT 50458 736 26 gland gland NN 50458 736 27 is be VBZ 50458 736 28 excised excise VBN 50458 736 29 . . . 50458 737 1 It -PRON- PRP 50458 737 2 seems seem VBZ 50458 737 3 probable probable JJ 50458 737 4 , , , 50458 737 5 however however RB 50458 737 6 , , , 50458 737 7 that that IN 50458 737 8 this this DT 50458 737 9 product product NN 50458 737 10 is be VBZ 50458 737 11 not not RB 50458 737 12 the the DT 50458 737 13 principal principal JJ 50458 737 14 agent agent NN 50458 737 15 of of IN 50458 737 16 the the DT 50458 737 17 thyroid thyroid NNP 50458 737 18 gland gland NNP 50458 737 19 . . . 50458 738 1 [ [ -LRB- 50458 738 2 91 91 CD 50458 738 3 ] ] -RRB- 50458 738 4 _ _ NNP 50458 738 5 Semaine Semaine NNP 50458 738 6 Médicale Médicale NNP 50458 738 7 _ _ NNP 50458 738 8 , , , 50458 738 9 Apr. April NNP 50458 739 1 3 3 CD 50458 739 2 , , , 50458 739 3 1895 1895 CD 50458 739 4 , , , 50458 739 5 p. p. NN 50458 739 6 138 138 CD 50458 739 7 . . . 50458 740 1 From from IN 50458 740 2 the the DT 50458 740 3 researches research NNS 50458 740 4 of of IN 50458 740 5 Schaeffer Schaeffer NNP 50458 740 6 , , , 50458 740 7 Roos Roos NNP 50458 740 8 , , , 50458 740 9 and and CC 50458 740 10 Sigmund Sigmund NNP 50458 740 11 Fraenkel[92 Fraenkel[92 NNP 50458 740 12 ] ] -RRB- 50458 740 13 it -PRON- PRP 50458 740 14 results result VBZ 50458 740 15 that that IN 50458 740 16 the the DT 50458 740 17 active active JJ 50458 740 18 principle principle NN 50458 740 19 of of IN 50458 740 20 the the DT 50458 740 21 gland gland NN 50458 740 22 is be VBZ 50458 740 23 not not RB 50458 740 24 a a DT 50458 740 25 toxin toxin NN 50458 740 26 , , , 50458 740 27 but but CC 50458 740 28 a a DT 50458 740 29 purely purely RB 50458 740 30 chemical chemical JJ 50458 740 31 substance substance NN 50458 740 32 , , , 50458 740 33 a a DT 50458 740 34 true true JJ 50458 740 35 leucomaine leucomaine NN 50458 740 36 , , , 50458 740 37 which which WDT 50458 740 38 has have VBZ 50458 740 39 received receive VBN 50458 740 40 the the DT 50458 740 41 name name NN 50458 740 42 _ _ NNP 50458 740 43 thyroantitoxin thyroantitoxin NN 50458 740 44 _ _ NNP 50458 740 45 . . . 50458 741 1 [ [ -LRB- 50458 741 2 92 92 CD 50458 741 3 ] ] -RRB- 50458 741 4 _ _ NNP 50458 741 5 Wiener Wiener NNP 50458 741 6 Med Med NNP 50458 741 7 . . . 50458 742 1 Blätter Blätter NNP 50458 742 2 _ _ NNP 50458 742 3 , , , 50458 742 4 No no UH 50458 742 5 . . . 50458 743 1 48 48 CD 50458 743 2 ; ; : 50458 743 3 and and CC 50458 743 4 _ _ NNP 50458 743 5 Gesellsch Gesellsch NNP 50458 743 6 . . . 50458 744 1 d. d. NNP 50458 744 2 Aerzte Aerzte NNP 50458 744 3 in in IN 50458 744 4 Wien Wien NNP 50458 744 5 _ _ NNP 50458 744 6 , , , 50458 744 7 Nov. November NNP 50458 744 8 22 22 CD 50458 744 9 , , , 50458 744 10 1895 1895 CD 50458 744 11 . . . 50458 745 1 On on IN 50458 745 2 the the DT 50458 745 3 other other JJ 50458 745 4 hand hand NN 50458 745 5 , , , 50458 745 6 Baumann Baumann NNP 50458 745 7 quite quite RB 50458 745 8 recently recently RB 50458 745 9 extracted extract VBD 50458 745 10 from from IN 50458 745 11 the the DT 50458 745 12 thyroid thyroid NN 50458 745 13 gland gland NNP 50458 745 14 an an DT 50458 745 15 iodized iodized JJ 50458 745 16 substance substance NN 50458 745 17 , , , 50458 745 18 which which WDT 50458 745 19 he -PRON- PRP 50458 745 20 named name VBD 50458 745 21 _ _ NNP 50458 745 22 thyroiodine thyroiodine NN 50458 745 23 _ _ NNP 50458 745 24 . . . 50458 746 1 [ [ -LRB- 50458 746 2 93 93 CD 50458 746 3 ] ] -RRB- 50458 746 4 [ [ -LRB- 50458 746 5 93 93 CD 50458 746 6 ] ] -RRB- 50458 746 7 _ _ NNP 50458 746 8 Zeitschr Zeitschr NNP 50458 746 9 . . . 50458 747 1 f. f. NNP 50458 747 2 Physiol Physiol NNP 50458 747 3 . . . 50458 748 1 Chem Chem NNP 50458 748 2 . . . 50458 748 3 _ _ NNP 50458 748 4 , , , 50458 748 5 XXI XXI NNP 50458 748 6 , , , 50458 748 7 pp pp NNP 50458 748 8 . . . 50458 749 1 319 319 CD 50458 749 2 and and CC 50458 749 3 481 481 CD 50458 749 4 ; ; : 50458 749 5 and and CC 50458 749 6 XXII XXII NNP 50458 749 7 , , , 50458 749 8 p. p. NN 50458 749 9 1 1 CD 50458 749 10 . . . 50458 750 1 ARMAND ARMAND NNP 50458 750 2 GAUTIER GAUTIER NNP 50458 750 3 : : : 50458 750 4 Chimie Chimie NNP 50458 750 5 Biologique Biologique NNP 50458 750 6 , , , 50458 750 7 2d 2d CD 50458 750 8 edit edit NN 50458 750 9 . . . 50458 750 10 , , , 50458 750 11 pp pp NNP 50458 750 12 . . . 50458 751 1 330 330 CD 50458 751 2 - - SYM 50458 751 3 332 332 CD 50458 751 4 . . . 50458 752 1 Masson Masson NNP 50458 752 2 , , , 50458 752 3 publ publ NNS 50458 752 4 . . . 50458 753 1 The the DT 50458 753 2 suprarenal suprarenal JJ 50458 753 3 capsules capsule NNS 50458 753 4 also also RB 50458 753 5 possess possess VBP 50458 753 6 properties property NNS 50458 753 7 that that WDT 50458 753 8 have have VBP 50458 753 9 often often RB 50458 753 10 attracted attract VBN 50458 753 11 the the DT 50458 753 12 attention attention NN 50458 753 13 of of IN 50458 753 14 physiologists physiologist NNS 50458 753 15 during during IN 50458 753 16 the the DT 50458 753 17 last last JJ 50458 753 18 few few JJ 50458 753 19 years year NNS 50458 753 20 . . . 50458 754 1 They -PRON- PRP 50458 754 2 are be VBP 50458 754 3 considered consider VBN 50458 754 4 as as IN 50458 754 5 being be VBG 50458 754 6 , , , 50458 754 7 just just RB 50458 754 8 like like IN 50458 754 9 the the DT 50458 754 10 thyroid thyroid NNP 50458 754 11 gland gland NNP 50458 754 12 , , , 50458 754 13 producers producer NNS 50458 754 14 of of IN 50458 754 15 antitoxins antitoxin NNS 50458 754 16 ; ; : 50458 754 17 they -PRON- PRP 50458 754 18 destroy destroy VBP 50458 754 19 , , , 50458 754 20 or or CC 50458 754 21 seem seem VBP 50458 754 22 to to TO 50458 754 23 destroy destroy VB 50458 754 24 , , , 50458 754 25 toxins toxin NNS 50458 754 26 that that WDT 50458 754 27 are be VBP 50458 754 28 artificially artificially RB 50458 754 29 introduced introduce VBN 50458 754 30 into into IN 50458 754 31 the the DT 50458 754 32 circulation circulation NN 50458 754 33 . . . 50458 755 1 Albanèse[94 Albanèse[94 NFP 50458 755 2 ] ] -RRB- 50458 755 3 maintains maintain VBZ 50458 755 4 that that IN 50458 755 5 the the DT 50458 755 6 function function NN 50458 755 7 of of IN 50458 755 8 the the DT 50458 755 9 suprarenal suprarenal JJ 50458 755 10 capsules capsule NNS 50458 755 11 is be VBZ 50458 755 12 to to TO 50458 755 13 neutralize neutralize VB 50458 755 14 neurine neurine NNP 50458 755 15 , , , 50458 755 16 the the DT 50458 755 17 toxic toxic JJ 50458 755 18 product product NN 50458 755 19 of of IN 50458 755 20 the the DT 50458 755 21 disassimilation disassimilation NN 50458 755 22 of of IN 50458 755 23 the the DT 50458 755 24 nervous nervous JJ 50458 755 25 system system NN 50458 755 26 ; ; : 50458 755 27 this this DT 50458 755 28 view view NN 50458 755 29 , , , 50458 755 30 however however RB 50458 755 31 , , , 50458 755 32 is be VBZ 50458 755 33 opposed oppose VBN 50458 755 34 by by IN 50458 755 35 Boinet[95 boinet[95 CD 50458 755 36 ] ] -RRB- 50458 755 37 and and CC 50458 755 38 Langlois Langlois NNP 50458 755 39 . . . 50458 756 1 [ [ -LRB- 50458 756 2 96 96 CD 50458 756 3 ] ] -RRB- 50458 756 4 On on IN 50458 756 5 the the DT 50458 756 6 contrary contrary NN 50458 756 7 , , , 50458 756 8 it -PRON- PRP 50458 756 9 has have VBZ 50458 756 10 been be VBN 50458 756 11 definitely definitely RB 50458 756 12 proven prove VBN 50458 756 13 that that IN 50458 756 14 the the DT 50458 756 15 suprarenal suprarenal JJ 50458 756 16 glands gland NNS 50458 756 17 exert exert VBP 50458 756 18 a a DT 50458 756 19 specific specific JJ 50458 756 20 action action NN 50458 756 21 on on IN 50458 756 22 the the DT 50458 756 23 poisons poison NNS 50458 756 24 of of IN 50458 756 25 muscular muscular JJ 50458 756 26 origin origin NN 50458 756 27 . . . 50458 757 1 Abelous abelous JJ 50458 757 2 and and CC 50458 757 3 Langlois[97 Langlois[97 NNP 50458 757 4 ] ] -RRB- 50458 757 5 have have VBP 50458 757 6 in in IN 50458 757 7 fact fact NN 50458 757 8 demonstrated demonstrate VBN 50458 757 9 that that IN 50458 757 10 the the DT 50458 757 11 alcoholic alcoholic JJ 50458 757 12 extract extract NN 50458 757 13 of of IN 50458 757 14 the the DT 50458 757 15 muscle muscle NN 50458 757 16 of of IN 50458 757 17 a a DT 50458 757 18 decapsulated decapsulate VBN 50458 757 19 animal animal NN 50458 757 20 has have VBZ 50458 757 21 the the DT 50458 757 22 same same JJ 50458 757 23 properties property NNS 50458 757 24 as as IN 50458 757 25 the the DT 50458 757 26 extract extract NN 50458 757 27 of of IN 50458 757 28 tetanized tetanized JJ 50458 757 29 muscle muscle NN 50458 757 30 ; ; : 50458 757 31 the the DT 50458 757 32 decapsulated decapsulate VBN 50458 757 33 animal animal NN 50458 757 34 gives give VBZ 50458 757 35 ergographic ergographic JJ 50458 757 36 tracings tracing NNS 50458 757 37 analogous analogous JJ 50458 757 38 to to IN 50458 757 39 those those DT 50458 757 40 afforded afford VBN 50458 757 41 by by IN 50458 757 42 tetanized tetanize VBN 50458 757 43 animals animal NNS 50458 757 44 . . . 50458 758 1 The the DT 50458 758 2 removal removal NN 50458 758 3 of of IN 50458 758 4 the the DT 50458 758 5 suprarenal suprarenal JJ 50458 758 6 capsule capsule NN 50458 758 7 from from IN 50458 758 8 an an DT 50458 758 9 animal animal NN 50458 758 10 brings bring VBZ 50458 758 11 results result NNS 50458 758 12 , , , 50458 758 13 hence hence RB 50458 758 14 , , , 50458 758 15 analogous analogous JJ 50458 758 16 to to IN 50458 758 17 those those DT 50458 758 18 of of IN 50458 758 19 fatigue fatigue NN 50458 758 20 -- -- : 50458 758 21 that that DT 50458 758 22 is be VBZ 50458 758 23 to to TO 50458 758 24 say say VB 50458 758 25 , , , 50458 758 26 that that IN 50458 758 27 the the DT 50458 758 28 toxic toxic JJ 50458 758 29 substances substance NNS 50458 758 30 which which WDT 50458 758 31 accumulate accumulate VBP 50458 758 32 as as IN 50458 758 33 a a DT 50458 758 34 result result NN 50458 758 35 of of IN 50458 758 36 the the DT 50458 758 37 decapsulation decapsulation NN 50458 758 38 resemble resemble VBP 50458 758 39 those those DT 50458 758 40 that that WDT 50458 758 41 result result VBP 50458 758 42 from from IN 50458 758 43 muscular muscular JJ 50458 758 44 exertion exertion NN 50458 758 45 . . . 50458 759 1 The the DT 50458 759 2 suprarenal suprarenal JJ 50458 759 3 capsules capsule NNS 50458 759 4 exert exert VBP 50458 759 5 their -PRON- PRP$ 50458 759 6 action action NN 50458 759 7 furthermore furthermore RB 50458 759 8 on on IN 50458 759 9 other other JJ 50458 759 10 toxic toxic JJ 50458 759 11 products product NNS 50458 759 12 as as RB 50458 759 13 well well RB 50458 759 14 , , , 50458 759 15 as as IN 50458 759 16 Guieysse[98 Guieysse[98 NNP 50458 759 17 ] ] -RRB- 50458 759 18 has have VBZ 50458 759 19 shown show VBN 50458 759 20 , , , 50458 759 21 and and CC 50458 759 22 particularly particularly RB 50458 759 23 on on IN 50458 759 24 the the DT 50458 759 25 exogenous exogenous JJ 50458 759 26 poisons poison NNS 50458 759 27 . . . 50458 760 1 In in IN 50458 760 2 conclusion conclusion NN 50458 760 3 , , , 50458 760 4 it -PRON- PRP 50458 760 5 may may MD 50458 760 6 be be VB 50458 760 7 said say VBN 50458 760 8 that that IN 50458 760 9 the the DT 50458 760 10 matter matter NN 50458 760 11 concerns concern VBZ 50458 760 12 a a DT 50458 760 13 most most RBS 50458 760 14 important important JJ 50458 760 15 rôle rôle NN 50458 760 16 , , , 50458 760 17 and and CC 50458 760 18 we -PRON- PRP 50458 760 19 can can MD 50458 760 20 not not RB 50458 760 21 do do VB 50458 760 22 better well RBR 50458 760 23 in in IN 50458 760 24 this this DT 50458 760 25 respect respect NN 50458 760 26 than than IN 50458 760 27 to to TO 50458 760 28 refer refer VB 50458 760 29 the the DT 50458 760 30 reader reader NN 50458 760 31 to to IN 50458 760 32 the the DT 50458 760 33 memoir memoir NN 50458 760 34 presented present VBN 50458 760 35 by by IN 50458 760 36 Sergent Sergent NNP 50458 760 37 and and CC 50458 760 38 Bernard Bernard NNP 50458 760 39 to to IN 50458 760 40 the the DT 50458 760 41 Académie Académie NNP 50458 760 42 de de IN 50458 760 43 Médecine Médecine NNP 50458 760 44 in in IN 50458 760 45 1902 1902 CD 50458 760 46 and and CC 50458 760 47 entitled entitle VBN 50458 760 48 _ _ NNP 50458 760 49 l'Insuffisance l'Insuffisance NNP 50458 760 50 Surrénale Surrénale NNP 50458 760 51 _ _ NNP 50458 760 52 . . . 50458 761 1 [ [ -LRB- 50458 761 2 99 99 CD 50458 761 3 ] ] -RRB- 50458 761 4 [ [ -LRB- 50458 761 5 94 94 CD 50458 761 6 ] ] -RRB- 50458 761 7 ALBANÈSE albanèse NN 50458 761 8 : : : 50458 761 9 Recherches recherche NNS 50458 761 10 sur sur FW 50458 761 11 les les FW 50458 761 12 fonctions fonction NNS 50458 761 13 des des FW 50458 761 14 capsules capsules NNP 50458 761 15 surrénales surrénale NNS 50458 761 16 . . . 50458 762 1 _ _ NNP 50458 762 2 Arch Arch NNP 50458 762 3 . . . 50458 763 1 Italiennes Italiennes NNP 50458 763 2 Biol Biol NNP 50458 763 3 . . . 50458 763 4 _ _ NNP 50458 763 5 , , , 50458 763 6 1892 1892 CD 50458 763 7 . . . 50458 764 1 [ [ -LRB- 50458 764 2 95 95 CD 50458 764 3 ] ] -RRB- 50458 764 4 BOINET BOINET NNP 50458 764 5 : : : 50458 764 6 _ _ NNP 50458 764 7 Compt Compt NNP 50458 764 8 . . . 50458 765 1 rend rend VB 50458 765 2 . . . 50458 766 1 Soc Soc NNP 50458 766 2 . . . 50458 767 1 de de NNP 50458 767 2 Biol Biol NNP 50458 767 3 . . . 50458 767 4 _ _ NNP 50458 767 5 , , , 50458 767 6 Mch Mch NNP 50458 767 7 . . . 50458 768 1 1896 1896 CD 50458 768 2 . . . 50458 769 1 [ [ -LRB- 50458 769 2 96 96 CD 50458 769 3 ] ] -RRB- 50458 769 4 See see VB 50458 769 5 _ _ NNP 50458 769 6 Compt Compt NNP 50458 769 7 . . . 50458 770 1 rend rend VB 50458 770 2 . . . 50458 771 1 de de NNP 50458 771 2 Biol Biol NNP 50458 771 3 . . . 50458 772 1 et et FW 50458 772 2 Arch arch JJ 50458 772 3 . . . 50458 773 1 Physiologie Physiologie NNP 50458 773 2 _ _ NNP 50458 773 3 , , , 50458 773 4 1891 1891 CD 50458 773 5 - - SYM 50458 773 6 1897 1897 CD 50458 773 7 . . . 50458 774 1 [ [ -LRB- 50458 774 2 97 97 CD 50458 774 3 ] ] -RRB- 50458 774 4 LANGLOIS LANGLOIS NNP 50458 774 5 : : : 50458 774 6 Thèse Thèse NNP 50458 774 7 de de FW 50458 774 8 doctorat doctorat FW 50458 774 9 en en IN 50458 774 10 Méd Méd NNP 50458 774 11 . . . 50458 774 12 , , , 50458 774 13 Paris Paris NNP 50458 774 14 , , , 50458 774 15 1897 1897 CD 50458 774 16 . . . 50458 775 1 [ [ -LRB- 50458 775 2 98 98 CD 50458 775 3 ] ] -RRB- 50458 775 4 GUIEYSSE GUIEYSSE NNP 50458 775 5 : : : 50458 775 6 _ _ NNP 50458 775 7 Les Les NNP 50458 775 8 capsules capsule VBZ 50458 775 9 surrénales surrénale NNS 50458 775 10 du du NNP 50458 775 11 cobaye cobaye NNP 50458 775 12 _ _ NNP 50458 775 13 , , , 50458 775 14 Thèse Thèse NNP 50458 775 15 , , , 50458 775 16 Paris Paris NNP 50458 775 17 , , , 50458 775 18 1901 1901 CD 50458 775 19 . . . 50458 776 1 [ [ -LRB- 50458 776 2 99 99 CD 50458 776 3 ] ] -RRB- 50458 776 4 Encyclopédie Encyclopédie NNP 50458 776 5 Léauté Léauté NNP 50458 776 6 , , , 50458 776 7 CCCXIV CCCXIV NNP 50458 776 8 , , , 50458 776 9 Masson Masson NNP 50458 776 10 , , , 50458 776 11 publ publ NNS 50458 776 12 . . . 50458 776 13 , , , 50458 776 14 Paris Paris NNP 50458 776 15 , , , 50458 776 16 1904 1904 CD 50458 776 17 . . . 50458 777 1 CHAPTER CHAPTER NNP 50458 777 2 IV IV NNP 50458 777 3 . . . 50458 778 1 THE the DT 50458 778 2 MICROBIAL MICROBIAL NNP 50458 778 3 TOXINS toxin NNS 50458 778 4 . . . 50458 779 1 There there EX 50458 779 2 is be VBZ 50458 779 3 but but CC 50458 779 4 one one CD 50458 779 5 way way NN 50458 779 6 of of IN 50458 779 7 characterizing characterize VBG 50458 779 8 the the DT 50458 779 9 toxic toxic JJ 50458 779 10 poisons poison NNS 50458 779 11 secreted secrete VBN 50458 779 12 by by IN 50458 779 13 microbes microbe NNS 50458 779 14 , , , 50458 779 15 and and CC 50458 779 16 that that DT 50458 779 17 is be VBZ 50458 779 18 to to TO 50458 779 19 apply apply VB 50458 779 20 to to IN 50458 779 21 them -PRON- PRP 50458 779 22 the the DT 50458 779 23 name name NN 50458 779 24 of of IN 50458 779 25 the the DT 50458 779 26 microbes microbe NNS 50458 779 27 generating generate VBG 50458 779 28 them -PRON- PRP 50458 779 29 ; ; : 50458 779 30 thus thus RB 50458 779 31 the the DT 50458 779 32 soluble soluble JJ 50458 779 33 and and CC 50458 779 34 toxic toxic JJ 50458 779 35 poison poison NN 50458 779 36 of of IN 50458 779 37 the the DT 50458 779 38 tetanus tetanus NNP 50458 779 39 bacilli bacilli NNP 50458 779 40 has have VBZ 50458 779 41 received receive VBN 50458 779 42 the the DT 50458 779 43 name name NN 50458 779 44 _ _ NNP 50458 779 45 tetanus tetanus NN 50458 779 46 toxin toxin NNP 50458 779 47 _ _ NNP 50458 779 48 . . . 50458 780 1 In in IN 50458 780 2 toxic toxic JJ 50458 780 3 microbial microbial JJ 50458 780 4 cultures culture NNS 50458 780 5 it -PRON- PRP 50458 780 6 is be VBZ 50458 780 7 necessary necessary JJ 50458 780 8 to to TO 50458 780 9 distinguish distinguish VB 50458 780 10 the the DT 50458 780 11 toxins toxin NNS 50458 780 12 proper proper JJ 50458 780 13 from from IN 50458 780 14 the the DT 50458 780 15 toxic toxic JJ 50458 780 16 alkaloids alkaloid NNS 50458 780 17 ( ( -LRB- 50458 780 18 ptomaines ptomaine NNS 50458 780 19 ) ) -RRB- 50458 780 20 which which WDT 50458 780 21 generally generally RB 50458 780 22 accompany accompany VBP 50458 780 23 them -PRON- PRP 50458 780 24 ; ; : 50458 780 25 this this DT 50458 780 26 is be VBZ 50458 780 27 easily easily RB 50458 780 28 accomplished accomplish VBN 50458 780 29 by by IN 50458 780 30 evaporating evaporate VBG 50458 780 31 the the DT 50458 780 32 solution solution NN 50458 780 33 in in IN 50458 780 34 a a DT 50458 780 35 vacuum vacuum NN 50458 780 36 at at IN 50458 780 37 about about RB 50458 780 38 30 30 CD 50458 780 39 ° ° , 50458 780 40 C C NNP 50458 780 41 . . NNP 50458 780 42 , , , 50458 780 43 and and CC 50458 780 44 then then RB 50458 780 45 treating treat VBG 50458 780 46 with with IN 50458 780 47 alcohol alcohol NN 50458 780 48 and and CC 50458 780 49 ether ether NN 50458 780 50 , , , 50458 780 51 in in IN 50458 780 52 which which WDT 50458 780 53 the the DT 50458 780 54 alkaloids alkaloid NNS 50458 780 55 are be VBP 50458 780 56 soluble soluble JJ 50458 780 57 , , , 50458 780 58 while while IN 50458 780 59 the the DT 50458 780 60 true true JJ 50458 780 61 toxins toxin NNS 50458 780 62 are be VBP 50458 780 63 insoluble insoluble JJ 50458 780 64 . . . 50458 781 1 By by IN 50458 781 2 fractional fractional JJ 50458 781 3 precipitation precipitation NN 50458 781 4 with with IN 50458 781 5 alcohol alcohol NN 50458 781 6 it -PRON- PRP 50458 781 7 is be VBZ 50458 781 8 easy easy JJ 50458 781 9 to to TO 50458 781 10 isolate isolate VB 50458 781 11 the the DT 50458 781 12 peptones peptone NNS 50458 781 13 and and CC 50458 781 14 true true JJ 50458 781 15 toxins toxin NNS 50458 781 16 . . . 50458 782 1 The the DT 50458 782 2 microbial microbial JJ 50458 782 3 toxins toxin NNS 50458 782 4 possess possess VBP 50458 782 5 two two CD 50458 782 6 essential essential JJ 50458 782 7 properties property NNS 50458 782 8 ; ; : 50458 782 9 one one CD 50458 782 10 the the DT 50458 782 11 pyogenic pyogenic JJ 50458 782 12 property property NN 50458 782 13 , , , 50458 782 14 thanks thank NNS 50458 782 15 to to IN 50458 782 16 which which WDT 50458 782 17 the the DT 50458 782 18 toxins toxin NNS 50458 782 19 first first RB 50458 782 20 attract attract NN 50458 782 21 , , , 50458 782 22 then then RB 50458 782 23 destroy destroy VB 50458 782 24 the the DT 50458 782 25 white white JJ 50458 782 26 blood blood NN 50458 782 27 corpuscles corpuscle NNS 50458 782 28 or or CC 50458 782 29 leucocytes leucocyte NNS 50458 782 30 , , , 50458 782 31 and and CC 50458 782 32 transform transform VB 50458 782 33 them -PRON- PRP 50458 782 34 into into IN 50458 782 35 pus pus NNP 50458 782 36 , , , 50458 782 37 and and CC 50458 782 38 the the DT 50458 782 39 other other JJ 50458 782 40 the the DT 50458 782 41 pyretogenic pyretogenic NN 50458 782 42 property property NN 50458 782 43 , , , 50458 782 44 which which WDT 50458 782 45 appears appear VBZ 50458 782 46 to to TO 50458 782 47 belong belong VB 50458 782 48 only only RB 50458 782 49 quite quite RB 50458 782 50 indirectly indirectly RB 50458 782 51 to to IN 50458 782 52 the the DT 50458 782 53 pyogenic pyogenic JJ 50458 782 54 substance substance NN 50458 782 55 . . . 50458 783 1 The the DT 50458 783 2 toxins toxin NNS 50458 783 3 in in IN 50458 783 4 general general NNP 50458 783 5 retard retard VBP 50458 783 6 the the DT 50458 783 7 heart heart NN 50458 783 8 action action NN 50458 783 9 . . . 50458 784 1 We -PRON- PRP 50458 784 2 will will MD 50458 784 3 not not RB 50458 784 4 speak speak VB 50458 784 5 of of IN 50458 784 6 the the DT 50458 784 7 distinctions distinction NNS 50458 784 8 it -PRON- PRP 50458 784 9 has have VBZ 50458 784 10 been be VBN 50458 784 11 sought seek VBN 50458 784 12 to to TO 50458 784 13 establish establish VB 50458 784 14 between between IN 50458 784 15 the the DT 50458 784 16 substances substance NNS 50458 784 17 which which WDT 50458 784 18 possess possess VBP 50458 784 19 these these DT 50458 784 20 different different JJ 50458 784 21 properties property NNS 50458 784 22 , , , 50458 784 23 but but CC 50458 784 24 will will MD 50458 784 25 at at IN 50458 784 26 once once RB 50458 784 27 take take VB 50458 784 28 up up RP 50458 784 29 the the DT 50458 784 30 discussion discussion NN 50458 784 31 of of IN 50458 784 32 several several JJ 50458 784 33 of of IN 50458 784 34 the the DT 50458 784 35 microbial microbial JJ 50458 784 36 toxins toxin NNS 50458 784 37 . . . 50458 785 1 = = NFP 50458 785 2 Anthrax Anthrax NNP 50458 785 3 Toxin=[100 Toxin=[100 NNPS 50458 785 4 ] ] -RRB- 50458 785 5 ( ( -LRB- 50458 785 6 from from IN 50458 785 7 Bacillus Bacillus NNP 50458 785 8 Anthracis).--We Anthracis).--We NNP 50458 785 9 will will MD 50458 785 10 describe describe VB 50458 785 11 the the DT 50458 785 12 preparation preparation NN 50458 785 13 of of IN 50458 785 14 this this DT 50458 785 15 toxin toxin NN 50458 785 16 as as IN 50458 785 17 a a DT 50458 785 18 type type NN 50458 785 19 . . . 50458 786 1 [ [ -LRB- 50458 786 2 100 100 CD 50458 786 3 ] ] -RRB- 50458 786 4 ARLOING arloing NN 50458 786 5 , , , 50458 786 6 CORNEVIN CORNEVIN NNP 50458 786 7 , , , 50458 786 8 THOMAS THOMAS NNP 50458 786 9 : : : 50458 786 10 _ _ NNP 50458 786 11 Le Le NNP 50458 786 12 Charbon Charbon NNP 50458 786 13 Symptomatique Symptomatique NNP 50458 786 14 _ _ NNP 50458 786 15 , , , 50458 786 16 1st 1st JJ 50458 786 17 edit edit NN 50458 786 18 . . . 50458 786 19 , , , 50458 786 20 Paris Paris NNP 50458 786 21 ; ; : 50458 786 22 and and CC 50458 786 23 LE LE NNP 50458 786 24 DANTEC DANTEC NNP 50458 786 25 : : : 50458 786 26 _ _ NNP 50458 786 27 La La NNP 50458 786 28 Bactéridie Bactéridie NNP 50458 786 29 du du NNP 50458 786 30 Charbon Charbon NNP 50458 786 31 _ _ NNP 50458 786 32 , , , 50458 786 33 Masson Masson NNP 50458 786 34 , , , 50458 786 35 publ publ NNS 50458 786 36 . . . 50458 787 1 ; ; : 50458 787 2 STRAUS STRAUS NNP 50458 787 3 : : : 50458 787 4 _ _ NNP 50458 787 5 Le Le NNP 50458 787 6 Charbon Charbon NNP 50458 787 7 des des FW 50458 787 8 Animaux Animaux NNP 50458 787 9 et et FW 50458 787 10 de de FW 50458 787 11 l'Homme l'Homme NNP 50458 787 12 _ _ NNP 50458 787 13 , , , 50458 787 14 Paris Paris NNP 50458 787 15 , , , 50458 787 16 1887 1887 CD 50458 787 17 . . . 50458 788 1 The the DT 50458 788 2 cultures culture NNS 50458 788 3 of of IN 50458 788 4 the the DT 50458 788 5 bacillus bacillus NN 50458 788 6 are be VBP 50458 788 7 made make VBN 50458 788 8 in in IN 50458 788 9 Liebig Liebig NNP 50458 788 10 's 's POS 50458 788 11 bouillon bouillon NN 50458 788 12 , , , 50458 788 13 to to TO 50458 788 14 which which WDT 50458 788 15 has have VBZ 50458 788 16 been be VBN 50458 788 17 added add VBN 50458 788 18 0.1 0.1 CD 50458 788 19 % % NN 50458 788 20 of of IN 50458 788 21 fibrin fibrin NN 50458 788 22 , , , 50458 788 23 the the DT 50458 788 24 whole whole JJ 50458 788 25 being be VBG 50458 788 26 carefully carefully RB 50458 788 27 sterilized sterilize VBN 50458 788 28 for for IN 50458 788 29 a a DT 50458 788 30 long long JJ 50458 788 31 time time NN 50458 788 32 at at IN 50458 788 33 110 110 CD 50458 788 34 ° ° NNS 50458 788 35 C. C. NNP 50458 788 36 The the DT 50458 788 37 cultures culture NNS 50458 788 38 medium medium NN 50458 788 39 is be VBZ 50458 788 40 inoculated inoculate VBN 50458 788 41 with with IN 50458 788 42 a a DT 50458 788 43 drop drop NN 50458 788 44 of of IN 50458 788 45 blood blood NN 50458 788 46 taken take VBN 50458 788 47 from from IN 50458 788 48 the the DT 50458 788 49 heart heart NN 50458 788 50 or or CC 50458 788 51 spleen spleen NN 50458 788 52 of of IN 50458 788 53 an an DT 50458 788 54 animal animal NN 50458 788 55 that that WDT 50458 788 56 has have VBZ 50458 788 57 died die VBN 50458 788 58 of of IN 50458 788 59 anthrax anthrax NN 50458 788 60 . . . 50458 789 1 At at IN 50458 789 2 the the DT 50458 789 3 end end NN 50458 789 4 of of IN 50458 789 5 a a DT 50458 789 6 week week NN 50458 789 7 , , , 50458 789 8 the the DT 50458 789 9 culture culture NN 50458 789 10 is be VBZ 50458 789 11 filtered filter VBN 50458 789 12 , , , 50458 789 13 and and CC 50458 789 14 the the DT 50458 789 15 filtrate filtrate JJ 50458 789 16 acidulated acidulate VBN 50458 789 17 with with IN 50458 789 18 a a DT 50458 789 19 little little JJ 50458 789 20 acetic acetic JJ 50458 789 21 acid acid NN 50458 789 22 and and CC 50458 789 23 precipitated precipitate VBN 50458 789 24 by by IN 50458 789 25 adding add VBG 50458 789 26 powdered powder VBN 50458 789 27 ammonium ammonium NN 50458 789 28 sulphate sulphate NN 50458 789 29 . . . 50458 790 1 The the DT 50458 790 2 flocculent flocculent JJ 50458 790 3 precipitate precipitate NN 50458 790 4 is be VBZ 50458 790 5 collected collect VBN 50458 790 6 , , , 50458 790 7 washed wash VBN 50458 790 8 , , , 50458 790 9 dissolved dissolve VBN 50458 790 10 in in IN 50458 790 11 distilled distilled JJ 50458 790 12 water water NN 50458 790 13 , , , 50458 790 14 and and CC 50458 790 15 dialyzed dialyzed JJ 50458 790 16 . . . 50458 791 1 The the DT 50458 791 2 dialyzed dialyzed JJ 50458 791 3 solution solution NN 50458 791 4 is be VBZ 50458 791 5 concentrated concentrate VBN 50458 791 6 in in IN 50458 791 7 vacuo vacuo NNS 50458 791 8 at at IN 50458 791 9 40 40 CD 50458 791 10 - - SYM 50458 791 11 45 45 CD 50458 791 12 ° ° , 50458 791 13 C. C. NNP 50458 791 14 , , , 50458 791 15 and and CC 50458 791 16 precipitated precipitate VBN 50458 791 17 by by IN 50458 791 18 adding add VBG 50458 791 19 to to IN 50458 791 20 it -PRON- PRP 50458 791 21 alcohol alcohol NN 50458 791 22 . . . 50458 792 1 The the DT 50458 792 2 precipitate precipitate NN 50458 792 3 formed form VBN 50458 792 4 is be VBZ 50458 792 5 then then RB 50458 792 6 collected collect VBN 50458 792 7 and and CC 50458 792 8 dried dry VBN 50458 792 9 . . . 50458 793 1 [ [ -LRB- 50458 793 2 101 101 CD 50458 793 3 ] ] -RRB- 50458 793 4 [ [ -LRB- 50458 793 5 101 101 CD 50458 793 6 ] ] -RRB- 50458 793 7 HANKIN HANKIN NNP 50458 793 8 : : : 50458 793 9 _ _ NNP 50458 793 10 British British NNP 50458 793 11 Medical Medical NNP 50458 793 12 Journal Journal NNP 50458 793 13 _ _ NNP 50458 793 14 , , , 50458 793 15 Oct. October NNP 50458 793 16 12 12 CD 50458 793 17 , , , 50458 793 18 1889 1889 CD 50458 793 19 , , , 50458 793 20 and and CC 50458 793 21 July July NNP 50458 793 22 12 12 CD 50458 793 23 , , , 50458 793 24 1890 1890 CD 50458 793 25 . . . 50458 794 1 In in IN 50458 794 2 this this DT 50458 794 3 manner manner NN 50458 794 4 there there EX 50458 794 5 is be VBZ 50458 794 6 obtained obtain VBN 50458 794 7 a a DT 50458 794 8 grayish grayish NN 50458 794 9 - - HYPH 50458 794 10 white white JJ 50458 794 11 substance substance NN 50458 794 12 which which WDT 50458 794 13 is be VBZ 50458 794 14 soluble soluble JJ 50458 794 15 in in IN 50458 794 16 water water NN 50458 794 17 , , , 50458 794 18 and and CC 50458 794 19 which which WDT 50458 794 20 is be VBZ 50458 794 21 fatal fatal JJ 50458 794 22 in in IN 50458 794 23 large large JJ 50458 794 24 doses dose NNS 50458 794 25 , , , 50458 794 26 but but CC 50458 794 27 which which WDT 50458 794 28 , , , 50458 794 29 given give VBN 50458 794 30 in in IN 50458 794 31 repeated repeat VBN 50458 794 32 small small JJ 50458 794 33 doses dose NNS 50458 794 34 , , , 50458 794 35 confers confer NNS 50458 794 36 immunity immunity NN 50458 794 37 against against IN 50458 794 38 anthrax anthrax NN 50458 794 39 . . . 50458 795 1 According accord VBG 50458 795 2 to to IN 50458 795 3 Hankin Hankin NNP 50458 795 4 , , , 50458 795 5 it -PRON- PRP 50458 795 6 seems seem VBZ 50458 795 7 that that IN 50458 795 8 the the DT 50458 795 9 toxic toxic JJ 50458 795 10 property property NN 50458 795 11 of of IN 50458 795 12 this this DT 50458 795 13 toxin toxin NN 50458 795 14 is be VBZ 50458 795 15 due due JJ 50458 795 16 to to IN 50458 795 17 an an DT 50458 795 18 albumose albumose NN 50458 795 19 . . . 50458 796 1 Marchoux[102 Marchoux[102 NNS 50458 796 2 ] ] -RRB- 50458 796 3 has have VBZ 50458 796 4 been be VBN 50458 796 5 able able JJ 50458 796 6 to to TO 50458 796 7 confer confer VB 50458 796 8 immunity immunity NN 50458 796 9 upon upon IN 50458 796 10 sheep sheep NN 50458 796 11 by by IN 50458 796 12 injecting inject VBG 50458 796 13 first first JJ 50458 796 14 small small JJ 50458 796 15 quantities quantity NNS 50458 796 16 of of IN 50458 796 17 the the DT 50458 796 18 filtered filter VBN 50458 796 19 culture culture NN 50458 796 20 of of IN 50458 796 21 the the DT 50458 796 22 anthrax anthrax NN 50458 796 23 bacilli bacilli NNP 50458 796 24 , , , 50458 796 25 and and CC 50458 796 26 then then RB 50458 796 27 the the DT 50458 796 28 virulent virulent JJ 50458 796 29 anthrax anthrax NN 50458 796 30 itself -PRON- PRP 50458 796 31 . . . 50458 797 1 [ [ -LRB- 50458 797 2 102 102 CD 50458 797 3 ] ] -RRB- 50458 797 4 _ _ NNP 50458 797 5 Annal Annal NNP 50458 797 6 . . . 50458 798 1 Instit Instit NNP 50458 798 2 . . . 50458 799 1 Pasteur Pasteur NNP 50458 799 2 _ _ NNP 50458 799 3 , , , 50458 799 4 IX IX NNP 50458 799 5 , , , 50458 799 6 p. p. NN 50458 799 7 785 785 CD 50458 799 8 . . . 50458 800 1 The the DT 50458 800 2 animals animal NNS 50458 800 3 thus thus RB 50458 800 4 rendered render VBD 50458 800 5 immune immune JJ 50458 800 6 yield yield NN 50458 800 7 a a DT 50458 800 8 serum serum NN 50458 800 9 which which WDT 50458 800 10 may may MD 50458 800 11 be be VB 50458 800 12 used use VBN 50458 800 13 as as IN 50458 800 14 a a DT 50458 800 15 vaccin vaccin NNS 50458 800 16 against against IN 50458 800 17 anthrax anthrax NN 50458 800 18 , , , 50458 800 19 and and CC 50458 800 20 which which WDT 50458 800 21 even even RB 50458 800 22 possesses possess VBZ 50458 800 23 curative curative JJ 50458 800 24 properties property NNS 50458 800 25 under under IN 50458 800 26 certain certain JJ 50458 800 27 conditions condition NNS 50458 800 28 . . . 50458 801 1 In in IN 50458 801 2 every every DT 50458 801 3 case case NN 50458 801 4 the the DT 50458 801 5 acquired acquire VBN 50458 801 6 immunity immunity NN 50458 801 7 is be VBZ 50458 801 8 only only RB 50458 801 9 temporary temporary JJ 50458 801 10 . . . 50458 802 1 We -PRON- PRP 50458 802 2 will will MD 50458 802 3 recall recall VB 50458 802 4 to to TO 50458 802 5 recollection recollection VB 50458 802 6 the the DT 50458 802 7 method method NN 50458 802 8 employed employ VBN 50458 802 9 by by IN 50458 802 10 Pasteur Pasteur NNP 50458 802 11 for for IN 50458 802 12 vaccinating vaccinate VBG 50458 802 13 against against IN 50458 802 14 anthrax anthrax NN 50458 802 15 , , , 50458 802 16 using use VBG 50458 802 17 attenuated attenuate VBN 50458 802 18 cultures culture NNS 50458 802 19 , , , 50458 802 20 a a DT 50458 802 21 method method NN 50458 802 22 which which WDT 50458 802 23 is be VBZ 50458 802 24 practiced practice VBN 50458 802 25 daily daily RB 50458 802 26 at at IN 50458 802 27 the the DT 50458 802 28 present present JJ 50458 802 29 time time NN 50458 802 30 . . . 50458 803 1 [ [ -LRB- 50458 803 2 103 103 CD 50458 803 3 ] ] -RRB- 50458 803 4 [ [ -LRB- 50458 803 5 103 103 CD 50458 803 6 ] ] -RRB- 50458 803 7 CHAMBERLAND CHAMBERLAND NNP 50458 803 8 : : : 50458 803 9 _ _ NNP 50458 803 10 Le Le NNP 50458 803 11 Charbon Charbon NNP 50458 803 12 et et NNP 50458 803 13 la la NNP 50458 803 14 Vaccination Vaccination NNP 50458 803 15 Charbonneuse Charbonneuse NNP 50458 803 16 _ _ NNP 50458 803 17 , , , 50458 803 18 Paris Paris NNP 50458 803 19 , , , 50458 803 20 1887 1887 CD 50458 803 21 . . . 50458 804 1 PETERMANN PETERMANN NNP 50458 804 2 : : : 50458 804 3 _ _ NNP 50458 804 4 Annal Annal NNP 50458 804 5 . . . 50458 805 1 Instit Instit NNP 50458 805 2 . . . 50458 806 1 Pasteur Pasteur NNP 50458 806 2 _ _ NNP 50458 806 3 , , , 50458 806 4 VI VI NNP 50458 806 5 , , , 50458 806 6 p. p. NN 50458 806 7 32 32 CD 50458 806 8 . . . 50458 807 1 From from IN 50458 807 2 the the DT 50458 807 3 cultures culture NNS 50458 807 4 of of IN 50458 807 5 symptomatic symptomatic JJ 50458 807 6 anthrax anthrax NN 50458 807 7 ( ( -LRB- 50458 807 8 Bacillus Bacillus NNP 50458 807 9 Chauvæ Chauvæ NNP 50458 807 10 ) ) -RRB- 50458 807 11 Chauvée Chauvée NNP 50458 807 12 extracted extract VBD 50458 807 13 a a DT 50458 807 14 very very RB 50458 807 15 active active JJ 50458 807 16 toxin toxin NN 50458 807 17 which which WDT 50458 807 18 can can MD 50458 807 19 withstand withstand VB 50458 807 20 without without IN 50458 807 21 impairment impairment NN 50458 807 22 a a DT 50458 807 23 temperature temperature NN 50458 807 24 of of IN 50458 807 25 110 110 CD 50458 807 26 ° ° , 50458 807 27 C C NNP 50458 807 28 . . . 50458 808 1 [ [ -LRB- 50458 808 2 104 104 NNP 50458 808 3 ] ] -RRB- 50458 808 4 Roux[105 Roux[105 NNP 50458 808 5 ] ] -RRB- 50458 808 6 has have VBZ 50458 808 7 shown show VBN 50458 808 8 that that IN 50458 808 9 the the DT 50458 808 10 serum serum NN 50458 808 11 of of IN 50458 808 12 animals animal NNS 50458 808 13 that that WDT 50458 808 14 have have VBP 50458 808 15 succumbed succumb VBN 50458 808 16 to to IN 50458 808 17 the the DT 50458 808 18 symptomatic symptomatic JJ 50458 808 19 anthrax anthrax NN 50458 808 20 is be VBZ 50458 808 21 capable capable JJ 50458 808 22 of of IN 50458 808 23 vaccinating vaccinate VBG 50458 808 24 against against IN 50458 808 25 this this DT 50458 808 26 disease disease NN 50458 808 27 ; ; : 50458 808 28 we -PRON- PRP 50458 808 29 have have VBP 50458 808 30 here here RB 50458 808 31 a a DT 50458 808 32 new new JJ 50458 808 33 proof proof NN 50458 808 34 that that IN 50458 808 35 the the DT 50458 808 36 antitoxin antitoxin NN 50458 808 37 is be VBZ 50458 808 38 in in IN 50458 808 39 fact fact NN 50458 808 40 a a DT 50458 808 41 product product NN 50458 808 42 of of IN 50458 808 43 the the DT 50458 808 44 defense defense NN 50458 808 45 of of IN 50458 808 46 the the DT 50458 808 47 cells cell NNS 50458 808 48 of of IN 50458 808 49 the the DT 50458 808 50 organism organism NN 50458 808 51 , , , 50458 808 52 and and CC 50458 808 53 the the DT 50458 808 54 author author NN 50458 808 55 mentioned mention VBD 50458 808 56 has have VBZ 50458 808 57 been be VBN 50458 808 58 able able JJ 50458 808 59 to to TO 50458 808 60 vaccinate vaccinate VB 50458 808 61 guinea guinea NN 50458 808 62 - - HYPH 50458 808 63 pigs pig NNS 50458 808 64 by by IN 50458 808 65 injecting inject VBG 50458 808 66 into into IN 50458 808 67 the the DT 50458 808 68 peritoneum peritoneum NN 50458 808 69 culture culture NN 50458 808 70 bouillon bouillon NN 50458 808 71 sterilized sterilize VBN 50458 808 72 by by IN 50458 808 73 heating heat VBG 50458 808 74 to to IN 50458 808 75 115 115 CD 50458 808 76 ° ° NNS 50458 808 77 C. C. NNP 50458 808 78 or or CC 50458 808 79 by by IN 50458 808 80 filtering filter VBG 50458 808 81 through through IN 50458 808 82 porcelain porcelain NN 50458 808 83 . . . 50458 809 1 [ [ -LRB- 50458 809 2 104 104 CD 50458 809 3 ] ] -RRB- 50458 809 4 DEUTSCHMANN deutschmann NN 50458 809 5 : : : 50458 809 6 _ _ NNP 50458 809 7 Annal Annal NNP 50458 809 8 . . . 50458 810 1 Instit Instit NNP 50458 810 2 . . . 50458 811 1 Pasteur Pasteur NNP 50458 811 2 _ _ NNP 50458 811 3 , , , 50458 811 4 VIII VIII NNP 50458 811 5 , , , 50458 811 6 p. p. NN 50458 811 7 403 403 CD 50458 811 8 . . . 50458 812 1 [ [ -LRB- 50458 812 2 105 105 CD 50458 812 3 ] ] -RRB- 50458 812 4 _ _ NNP 50458 812 5 Annal Annal NNP 50458 812 6 . . . 50458 813 1 Inst inst RB 50458 813 2 . . . 50458 814 1 Pasteur Pasteur NNP 50458 814 2 _ _ NNP 50458 814 3 , , , 50458 814 4 Feb. February NNP 50458 814 5 1888 1888 CD 50458 814 6 . . . 50458 815 1 = = NFP 50458 815 2 Tubercular Tubercular NNP 50458 815 3 Toxin.=--The toxin.=--the NN 50458 815 4 culture culture NN 50458 815 5 bouillons bouillon NNS 50458 815 6 of of IN 50458 815 7 Koch Koch NNP 50458 815 8 's 's POS 50458 815 9 bacillus bacillus NN 50458 815 10 contain contain VBP 50458 815 11 one one CD 50458 815 12 or or CC 50458 815 13 more more RBR 50458 815 14 active active JJ 50458 815 15 substances substance NNS 50458 815 16 which which WDT 50458 815 17 constitute constitute VBP 50458 815 18 , , , 50458 815 19 and and CC 50458 815 20 which which WDT 50458 815 21 is be VBZ 50458 815 22 at at IN 50458 815 23 the the DT 50458 815 24 present present NN 50458 815 25 designated designate VBN 50458 815 26 as as IN 50458 815 27 , , , 50458 815 28 tuberculin tuberculin NN 50458 815 29 . . . 50458 816 1 [ [ -LRB- 50458 816 2 106 106 CD 50458 816 3 ] ] -RRB- 50458 816 4 Koch Koch NNP 50458 816 5 's 's POS 50458 816 6 therapeutic therapeutic JJ 50458 816 7 tuberculin tuberculin NN 50458 816 8 is be VBZ 50458 816 9 obtained obtain VBN 50458 816 10 by by IN 50458 816 11 evaporating evaporate VBG 50458 816 12 to to IN 50458 816 13 one one CD 50458 816 14 - - HYPH 50458 816 15 tenth tenth NN 50458 816 16 its -PRON- PRP$ 50458 816 17 volume volume NN 50458 816 18 a a DT 50458 816 19 culture culture NN 50458 816 20 bouillon bouillon NN 50458 816 21 of of IN 50458 816 22 Koch Koch NNP 50458 816 23 's 's POS 50458 816 24 tubercle tubercle NN 50458 816 25 bacilli bacilli NNP 50458 816 26 prepared prepare VBD 50458 816 27 from from IN 50458 816 28 a a DT 50458 816 29 4-per 4-per NNP 50458 816 30 cent cent NN 50458 816 31 . . . 50458 817 1 glycerinic glycerinic JJ 50458 817 2 mutton mutton NNP 50458 817 3 bouillon bouillon NNP 50458 817 4 , , , 50458 817 5 and and CC 50458 817 6 filtering filter VBG 50458 817 7 through through IN 50458 817 8 porcelain porcelain NN 50458 817 9 . . . 50458 818 1 By by IN 50458 818 2 fractional fractional JJ 50458 818 3 precipitation precipitation NN 50458 818 4 it -PRON- PRP 50458 818 5 is be VBZ 50458 818 6 possible possible JJ 50458 818 7 to to TO 50458 818 8 obtain obtain VB 50458 818 9 from from IN 50458 818 10 the the DT 50458 818 11 crude crude JJ 50458 818 12 tuberculin tuberculin NN 50458 818 13 so so RB 50458 818 14 prepared prepare VBD 50458 818 15 a a DT 50458 818 16 product product NN 50458 818 17 which which WDT 50458 818 18 is be VBZ 50458 818 19 considered consider VBN 50458 818 20 as as IN 50458 818 21 pure pure JJ 50458 818 22 tuberculin tuberculin NN 50458 818 23 , , , 50458 818 24 and and CC 50458 818 25 which which WDT 50458 818 26 possesses possess VBZ 50458 818 27 considerable considerable JJ 50458 818 28 activity activity NN 50458 818 29 . . . 50458 819 1 [ [ -LRB- 50458 819 2 106 106 CD 50458 819 3 ] ] -RRB- 50458 819 4 AUCLAIR AUCLAIR NNP 50458 819 5 : : : 50458 819 6 _ _ NNP 50458 819 7 Thèse Thèse NNP 50458 819 8 de de NNP 50458 819 9 doctorat doctorat NNP 50458 819 10 _ _ NNP 50458 819 11 , , , 50458 819 12 Paris Paris NNP 50458 819 13 , , , 50458 819 14 1897 1897 CD 50458 819 15 ; ; : 50458 819 16 and and CC 50458 819 17 _ _ NNP 50458 819 18 Arch Arch NNP 50458 819 19 . . . 50458 820 1 de de NNP 50458 820 2 Médecine Médecine NNP 50458 820 3 _ _ NNP 50458 820 4 , , , 50458 820 5 exp exp NN 50458 820 6 . . . 50458 821 1 1898 1898 CD 50458 821 2 . . . 50458 822 1 Prolonged prolonged JJ 50458 822 2 boiling boiling NN 50458 822 3 on on IN 50458 822 4 the the DT 50458 822 5 water water NN 50458 822 6 - - HYPH 50458 822 7 bath bath NN 50458 822 8 completely completely RB 50458 822 9 destroys destroy VBZ 50458 822 10 the the DT 50458 822 11 activity activity NN 50458 822 12 of of IN 50458 822 13 this this DT 50458 822 14 tuberculin tuberculin NN 50458 822 15 , , , 50458 822 16 which which WDT 50458 822 17 moreover moreover RB 50458 822 18 hardly hardly RB 50458 822 19 ever ever RB 50458 822 20 keeps keep VBZ 50458 822 21 longer long JJR 50458 822 22 than than IN 50458 822 23 three three CD 50458 822 24 weeks week NNS 50458 822 25 . . . 50458 823 1 It -PRON- PRP 50458 823 2 has have VBZ 50458 823 3 been be VBN 50458 823 4 found find VBN 50458 823 5 possible possible JJ 50458 823 6 to to TO 50458 823 7 preserve preserve VB 50458 823 8 it -PRON- PRP 50458 823 9 for for IN 50458 823 10 an an DT 50458 823 11 indefinite indefinite JJ 50458 823 12 period period NN 50458 823 13 , , , 50458 823 14 however however RB 50458 823 15 , , , 50458 823 16 by by IN 50458 823 17 adding add VBG 50458 823 18 to to IN 50458 823 19 it -PRON- PRP 50458 823 20 30 30 CD 50458 823 21 to to TO 50458 823 22 40 40 CD 50458 823 23 per per NN 50458 823 24 cent cent NN 50458 823 25 . . . 50458 824 1 of of IN 50458 824 2 glycerin glycerin NNP 50458 824 3 . . . 50458 825 1 It -PRON- PRP 50458 825 2 possesses possess VBZ 50458 825 3 all all PDT 50458 825 4 the the DT 50458 825 5 general general JJ 50458 825 6 reactions reaction NNS 50458 825 7 of of IN 50458 825 8 albuminoids albuminoid NNS 50458 825 9 . . . 50458 826 1 Tuberculin tuberculin NN 50458 826 2 is be VBZ 50458 826 3 not not RB 50458 826 4 toxic toxic JJ 50458 826 5 in in IN 50458 826 6 the the DT 50458 826 7 proper proper JJ 50458 826 8 sense sense NN 50458 826 9 of of IN 50458 826 10 the the DT 50458 826 11 word word NN 50458 826 12 . . . 50458 827 1 Injected inject VBN 50458 827 2 in in IN 50458 827 3 small small JJ 50458 827 4 quantities quantity NNS 50458 827 5 into into IN 50458 827 6 the the DT 50458 827 7 healthy healthy JJ 50458 827 8 human human NN 50458 827 9 being[107 being[107 NNP 50458 827 10 ] ] -RRB- 50458 827 11 and and CC 50458 827 12 into into IN 50458 827 13 healthy healthy JJ 50458 827 14 animals animal NNS 50458 827 15 , , , 50458 827 16 it -PRON- PRP 50458 827 17 exerts exert VBZ 50458 827 18 no no DT 50458 827 19 effect effect NN 50458 827 20 ; ; : 50458 827 21 on on IN 50458 827 22 the the DT 50458 827 23 other other JJ 50458 827 24 hand hand NN 50458 827 25 , , , 50458 827 26 however however RB 50458 827 27 , , , 50458 827 28 in in IN 50458 827 29 tubercular tubercular JJ 50458 827 30 organisms organism NNS 50458 827 31 , , , 50458 827 32 even even RB 50458 827 33 in in IN 50458 827 34 incipient incipient JJ 50458 827 35 stages stage NNS 50458 827 36 of of IN 50458 827 37 the the DT 50458 827 38 disease disease NN 50458 827 39 , , , 50458 827 40 even even RB 50458 827 41 where where WRB 50458 827 42 it -PRON- PRP 50458 827 43 is be VBZ 50458 827 44 almost almost RB 50458 827 45 impossible impossible JJ 50458 827 46 to to TO 50458 827 47 make make VB 50458 827 48 a a DT 50458 827 49 clinical clinical JJ 50458 827 50 diagnosis diagnosis NN 50458 827 51 , , , 50458 827 52 the the DT 50458 827 53 injection injection NN 50458 827 54 of of IN 50458 827 55 very very RB 50458 827 56 small small JJ 50458 827 57 quantities quantity NNS 50458 827 58 develops develop VBZ 50458 827 59 a a DT 50458 827 60 lively lively JJ 50458 827 61 and and CC 50458 827 62 characteristic characteristic JJ 50458 827 63 reaction reaction NN 50458 827 64 . . . 50458 828 1 [ [ -LRB- 50458 828 2 108 108 CD 50458 828 3 ] ] -RRB- 50458 828 4 [ [ -LRB- 50458 828 5 107 107 CD 50458 828 6 ] ] -RRB- 50458 828 7 KOCH KOCH NNP 50458 828 8 : : : 50458 828 9 _ _ NNP 50458 828 10 Deutsch Deutsch NNP 50458 828 11 . . . 50458 829 1 Med Med NNP 50458 829 2 . . . 50458 830 1 Woch Woch NNP 50458 830 2 . . . 50458 830 3 _ _ NNP 50458 830 4 , , , 50458 830 5 Nov. November NNP 50458 830 6 13 13 CD 50458 830 7 , , , 50458 830 8 1890 1890 CD 50458 830 9 - - SYM 50458 830 10 1897 1897 CD 50458 830 11 , , , 50458 830 12 No no UH 50458 830 13 . . . 50458 831 1 14 14 CD 50458 831 2 , , , 50458 831 3 p. p. NN 50458 831 4 209 209 CD 50458 831 5 . . . 50458 832 1 [ [ -LRB- 50458 832 2 108 108 CD 50458 832 3 ] ] -RRB- 50458 832 4 _ _ NNP 50458 832 5 Annal Annal NNP 50458 832 6 . . . 50458 833 1 de de NNP 50458 833 2 l'Instit l'Instit NNP 50458 833 3 . . . 50458 834 1 Pasteur Pasteur NNP 50458 834 2 _ _ NNP 50458 834 3 , , , 50458 834 4 V V NNP 50458 834 5 , , , 50458 834 6 p. p. NN 50458 834 7 191 191 CD 50458 834 8 ; ; : 50458 834 9 _ _ NNP 50458 834 10 Arch Arch NNP 50458 834 11 . . . 50458 835 1 de de NNP 50458 835 2 la la NNP 50458 835 3 Soc Soc NNP 50458 835 4 . . . 50458 836 1 Biol Biol NNP 50458 836 2 . . . 50458 837 1 de de NNP 50458 837 2 Saint Saint NNP 50458 837 3 - - HYPH 50458 837 4 Pétersbourg Pétersbourg NNP 50458 837 5 _ _ NNP 50458 837 6 , , , 50458 837 7 I -PRON- PRP 50458 837 8 , , , 50458 837 9 p. p. NN 50458 837 10 213 213 CD 50458 837 11 . . . 50458 838 1 Grasset Grasset NNP 50458 838 2 and and CC 50458 838 3 Vedel Vedel NNP 50458 838 4 consider consider VBP 50458 838 5 the the DT 50458 838 6 tuberculin tuberculin NN 50458 838 7 as as IN 50458 838 8 an an DT 50458 838 9 excellent excellent JJ 50458 838 10 means means NN 50458 838 11 of of IN 50458 838 12 diagnosing diagnose VBG 50458 838 13 tuberculosis tuberculosis NN 50458 838 14 in in IN 50458 838 15 man man NN 50458 838 16 , , , 50458 838 17 but but CC 50458 838 18 in in IN 50458 838 19 such such PDT 50458 838 20 a a DT 50458 838 21 case case NN 50458 838 22 it -PRON- PRP 50458 838 23 is be VBZ 50458 838 24 necessary necessary JJ 50458 838 25 to to TO 50458 838 26 operate operate VB 50458 838 27 with with IN 50458 838 28 the the DT 50458 838 29 greatest great JJS 50458 838 30 caution caution NN 50458 838 31 , , , 50458 838 32 with with IN 50458 838 33 very very RB 50458 838 34 small small JJ 50458 838 35 quantities quantity NNS 50458 838 36 of of IN 50458 838 37 the the DT 50458 838 38 tuberculin tuberculin NN 50458 838 39 , , , 50458 838 40 and and CC 50458 838 41 to to TO 50458 838 42 feel feel VB 50458 838 43 , , , 50458 838 44 in in IN 50458 838 45 some some DT 50458 838 46 sort sort NN 50458 838 47 , , , 50458 838 48 the the DT 50458 838 49 sensitiveness sensitiveness NN 50458 838 50 of of IN 50458 838 51 the the DT 50458 838 52 patient patient NN 50458 838 53 , , , 50458 838 54 particularly particularly RB 50458 838 55 in in IN 50458 838 56 the the DT 50458 838 57 case case NN 50458 838 58 of of IN 50458 838 59 children child NNS 50458 838 60 . . . 50458 839 1 It -PRON- PRP 50458 839 2 is be VBZ 50458 839 3 chiefly chiefly RB 50458 839 4 for for IN 50458 839 5 the the DT 50458 839 6 diagnosis diagnosis NN 50458 839 7 of of IN 50458 839 8 tuberculosis tuberculosis NN 50458 839 9 in in IN 50458 839 10 cattle cattle NNS 50458 839 11 , , , 50458 839 12 however however RB 50458 839 13 , , , 50458 839 14 that that IN 50458 839 15 tuberculin tuberculin NN 50458 839 16 is be VBZ 50458 839 17 valuable valuable JJ 50458 839 18 . . . 50458 840 1 Thanks thank NNS 50458 840 2 to to IN 50458 840 3 Nocard Nocard NNP 50458 840 4 , , , 50458 840 5 the the DT 50458 840 6 procedure procedure NN 50458 840 7 has have VBZ 50458 840 8 to to IN 50458 840 9 - - HYPH 50458 840 10 day day NN 50458 840 11 become become VB 50458 840 12 a a DT 50458 840 13 common common JJ 50458 840 14 practice practice NN 50458 840 15 . . . 50458 841 1 The the DT 50458 841 2 injection injection NN 50458 841 3 of of IN 50458 841 4 a a DT 50458 841 5 fairly fairly RB 50458 841 6 large large JJ 50458 841 7 dose dose NN 50458 841 8 , , , 50458 841 9 0.3 0.3 CD 50458 841 10 to to TO 50458 841 11 0.4 0.4 CD 50458 841 12 Gm Gm NNP 50458 841 13 . . . 50458 841 14 , , , 50458 841 15 according accord VBG 50458 841 16 to to IN 50458 841 17 the the DT 50458 841 18 size size NN 50458 841 19 of of IN 50458 841 20 the the DT 50458 841 21 animal animal NN 50458 841 22 , , , 50458 841 23 causes cause NNS 50458 841 24 , , , 50458 841 25 in in IN 50458 841 26 about about RB 50458 841 27 ten ten CD 50458 841 28 hours hour NNS 50458 841 29 or or CC 50458 841 30 so so RB 50458 841 31 , , , 50458 841 32 if if IN 50458 841 33 the the DT 50458 841 34 animal animal NN 50458 841 35 is be VBZ 50458 841 36 tuberculous tuberculous JJ 50458 841 37 , , , 50458 841 38 a a DT 50458 841 39 strong strong JJ 50458 841 40 febrile febrile NN 50458 841 41 reaction reaction NN 50458 841 42 with with IN 50458 841 43 an an DT 50458 841 44 elevation elevation NN 50458 841 45 of of IN 50458 841 46 temperature temperature NN 50458 841 47 of of IN 50458 841 48 1.5 1.5 CD 50458 841 49 to to TO 50458 841 50 3 3 CD 50458 841 51 ° ° , 50458 841 52 C. C. NNP 50458 841 53 , , , 50458 841 54 whereas whereas IN 50458 841 55 if if IN 50458 841 56 the the DT 50458 841 57 animal animal NN 50458 841 58 is be VBZ 50458 841 59 not not RB 50458 841 60 tuberculous tuberculous JJ 50458 841 61 no no DT 50458 841 62 such such JJ 50458 841 63 reaction reaction NN 50458 841 64 takes take VBZ 50458 841 65 place place NN 50458 841 66 . . . 50458 842 1 Cases case NNS 50458 842 2 in in IN 50458 842 3 which which WDT 50458 842 4 tuberculosis tuberculosis NN 50458 842 5 is be VBZ 50458 842 6 far far RB 50458 842 7 advanced advanced JJ 50458 842 8 , , , 50458 842 9 and and CC 50458 842 10 in in IN 50458 842 11 which which WDT 50458 842 12 the the DT 50458 842 13 organism organism NN 50458 842 14 is be VBZ 50458 842 15 impregnated impregnate VBN 50458 842 16 with with IN 50458 842 17 tuberculin tuberculin NN 50458 842 18 , , , 50458 842 19 do do VBP 50458 842 20 not not RB 50458 842 21 react react VB 50458 842 22 after after IN 50458 842 23 the the DT 50458 842 24 injection injection NN 50458 842 25 of of IN 50458 842 26 tuberculin tuberculin NN 50458 842 27 . . . 50458 843 1 [ [ -LRB- 50458 843 2 109 109 CD 50458 843 3 ] ] -RRB- 50458 843 4 [ [ -LRB- 50458 843 5 109 109 CD 50458 843 6 ] ] -RRB- 50458 843 7 NOCARD NOCARD NNP 50458 843 8 and and CC 50458 843 9 LECLAINCHE LECLAINCHE NNP 50458 843 10 : : : 50458 843 11 _ _ NNP 50458 843 12 Les Les NNP 50458 843 13 Maladies Maladies NNP 50458 843 14 Microbiennes Microbiennes NNP 50458 843 15 des des NNP 50458 843 16 Animaux Animaux NNP 50458 843 17 _ _ NNP 50458 843 18 . . . 50458 844 1 Tuberculin Tuberculin NNP 50458 844 2 does do VBZ 50458 844 3 not not RB 50458 844 4 confer confer VB 50458 844 5 immunity immunity NN 50458 844 6 , , , 50458 844 7 and and CC 50458 844 8 the the DT 50458 844 9 bacillus bacillus NN 50458 844 10 retains retain VBZ 50458 844 11 all all PDT 50458 844 12 its -PRON- PRP$ 50458 844 13 virulence virulence NN 50458 844 14 , , , 50458 844 15 even even RB 50458 844 16 in in IN 50458 844 17 injected inject VBN 50458 844 18 tissues tissue NNS 50458 844 19 ; ; : 50458 844 20 nevertheless nevertheless RB 50458 844 21 , , , 50458 844 22 the the DT 50458 844 23 return return NN 50458 844 24 to to IN 50458 844 25 health health NN 50458 844 26 of of IN 50458 844 27 animals animal NNS 50458 844 28 in in IN 50458 844 29 which which WDT 50458 844 30 injections injection NNS 50458 844 31 have have VBP 50458 844 32 been be VBN 50458 844 33 recently recently RB 50458 844 34 made make VBN 50458 844 35 may may MD 50458 844 36 be be VB 50458 844 37 due due IN 50458 844 38 to to IN 50458 844 39 the the DT 50458 844 40 action action NN 50458 844 41 of of IN 50458 844 42 large large JJ 50458 844 43 doses dose NNS 50458 844 44 of of IN 50458 844 45 the the DT 50458 844 46 serum serum NN 50458 844 47 ; ; : 50458 844 48 and and CC 50458 844 49 on on IN 50458 844 50 the the DT 50458 844 51 other other JJ 50458 844 52 hand hand NN 50458 844 53 the the DT 50458 844 54 tuberculin tuberculin NN 50458 844 55 , , , 50458 844 56 in in IN 50458 844 57 large large JJ 50458 844 58 quantities quantity NNS 50458 844 59 , , , 50458 844 60 may may MD 50458 844 61 render render VB 50458 844 62 the the DT 50458 844 63 location location NN 50458 844 64 unsuitable unsuitable JJ 50458 844 65 for for IN 50458 844 66 the the DT 50458 844 67 development development NN 50458 844 68 of of IN 50458 844 69 the the DT 50458 844 70 tubercle tubercle NN 50458 844 71 bacilli bacilli NNP 50458 844 72 . . . 50458 845 1 = = NFP 50458 845 2 Diphtheria Diphtheria NNP 50458 845 3 Toxin.=--The Toxin.=--The NNP 50458 845 4 most most RBS 50458 845 5 characteristic characteristic JJ 50458 845 6 property property NN 50458 845 7 of of IN 50458 845 8 the the DT 50458 845 9 diphtheria diphtheria NN 50458 845 10 bacillus bacillus NN 50458 845 11 is be VBZ 50458 845 12 the the DT 50458 845 13 production production NN 50458 845 14 , , , 50458 845 15 in in IN 50458 845 16 culture culture NN 50458 845 17 media medium NNS 50458 845 18 , , , 50458 845 19 of of IN 50458 845 20 a a DT 50458 845 21 special special JJ 50458 845 22 toxic toxic JJ 50458 845 23 substance substance NN 50458 845 24 which which WDT 50458 845 25 has have VBZ 50458 845 26 been be VBN 50458 845 27 named name VBN 50458 845 28 _ _ NNP 50458 845 29 diphtheritic diphtheritic JJ 50458 845 30 toxin toxin NN 50458 845 31 _ _ NNP 50458 845 32 ; ; : 50458 845 33 this this DT 50458 845 34 name name NN 50458 845 35 , , , 50458 845 36 however however RB 50458 845 37 , , , 50458 845 38 has have VBZ 50458 845 39 come come VBN 50458 845 40 to to TO 50458 845 41 be be VB 50458 845 42 also also RB 50458 845 43 extended extend VBN 50458 845 44 to to IN 50458 845 45 a a DT 50458 845 46 liquid liquid NN 50458 845 47 in in IN 50458 845 48 which which WDT 50458 845 49 the the DT 50458 845 50 bacilli bacilli NNP 50458 845 51 have have VBP 50458 845 52 lived live VBN 50458 845 53 , , , 50458 845 54 and and CC 50458 845 55 which which WDT 50458 845 56 has have VBZ 50458 845 57 been be VBN 50458 845 58 sterilized sterilize VBN 50458 845 59 by by IN 50458 845 60 filtration filtration NN 50458 845 61 or or CC 50458 845 62 by by IN 50458 845 63 any any DT 50458 845 64 other other JJ 50458 845 65 suitable suitable JJ 50458 845 66 process process NN 50458 845 67 . . . 50458 846 1 Roux roux VB 50458 846 2 and and CC 50458 846 3 Yersin[110 Yersin[110 NNS 50458 846 4 ] ] -RRB- 50458 846 5 were be VBD 50458 846 6 the the DT 50458 846 7 first first JJ 50458 846 8 to to TO 50458 846 9 affirm affirm VB 50458 846 10 that that IN 50458 846 11 diphtheria diphtheria NN 50458 846 12 is be VBZ 50458 846 13 an an DT 50458 846 14 autointoxication autointoxication NN 50458 846 15 caused cause VBN 50458 846 16 by by IN 50458 846 17 a a DT 50458 846 18 very very RB 50458 846 19 active active JJ 50458 846 20 poison poison NN 50458 846 21 formed form VBN 50458 846 22 by by IN 50458 846 23 the the DT 50458 846 24 microbe microbe NN 50458 846 25 in in IN 50458 846 26 the the DT 50458 846 27 restricted restricted JJ 50458 846 28 locality locality NN 50458 846 29 where where WRB 50458 846 30 it -PRON- PRP 50458 846 31 develops develop VBZ 50458 846 32 . . . 50458 847 1 In in IN 50458 847 2 order order NN 50458 847 3 to to TO 50458 847 4 obtain obtain VB 50458 847 5 this this DT 50458 847 6 toxin[111 toxin[111 NN 50458 847 7 ] ] -RRB- 50458 847 8 a a DT 50458 847 9 culture culture NN 50458 847 10 of of IN 50458 847 11 the the DT 50458 847 12 bacillus bacillus NN 50458 847 13 is be VBZ 50458 847 14 first first RB 50458 847 15 made make VBN 50458 847 16 in in IN 50458 847 17 a a DT 50458 847 18 mutton mutton NN 50458 847 19 bouillon bouillon NN 50458 847 20 made make VBD 50458 847 21 strongly strongly RB 50458 847 22 alkaline alkaline VB 50458 847 23 with with IN 50458 847 24 sodium sodium NN 50458 847 25 carbonate carbonate NN 50458 847 26 ( ( -LRB- 50458 847 27 10 10 CD 50458 847 28 grams gram NNS 50458 847 29 per per IN 50458 847 30 liter liter NN 50458 847 31 ) ) -RRB- 50458 847 32 , , , 50458 847 33 and and CC 50458 847 34 with with IN 50458 847 35 the the DT 50458 847 36 addition addition NN 50458 847 37 of of IN 50458 847 38 2 2 CD 50458 847 39 per per NN 50458 847 40 cent cent NN 50458 847 41 . . . 50458 848 1 of of IN 50458 848 2 peptone peptone NNP 50458 848 3 . . . 50458 849 1 At at IN 50458 849 2 the the DT 50458 849 3 end end NN 50458 849 4 of of IN 50458 849 5 about about RB 50458 849 6 one one CD 50458 849 7 month month NN 50458 849 8 , , , 50458 849 9 the the DT 50458 849 10 culture culture NN 50458 849 11 being be VBG 50458 849 12 kept keep VBN 50458 849 13 at at IN 50458 849 14 about about RB 50458 849 15 37 37 CD 50458 849 16 ° ° , 50458 849 17 C. C. NNP 50458 849 18 , , , 50458 849 19 the the DT 50458 849 20 liquid liquid NN 50458 849 21 is be VBZ 50458 849 22 filtered filter VBN 50458 849 23 through through IN 50458 849 24 porcelain porcelain NN 50458 849 25 . . . 50458 850 1 It -PRON- PRP 50458 850 2 is be VBZ 50458 850 3 indispensable indispensable JJ 50458 850 4 to to TO 50458 850 5 employ employ VB 50458 850 6 a a DT 50458 850 7 very very RB 50458 850 8 virulent virulent JJ 50458 850 9 bacillus bacillus NN 50458 850 10 ; ; : 50458 850 11 it -PRON- PRP 50458 850 12 is be VBZ 50458 850 13 hence hence RB 50458 850 14 frequently frequently RB 50458 850 15 advantageous advantageous JJ 50458 850 16 to to TO 50458 850 17 increase increase VB 50458 850 18 the the DT 50458 850 19 virulence virulence NN 50458 850 20 and and CC 50458 850 21 toxigenic toxigenic JJ 50458 850 22 power power NN 50458 850 23 of of IN 50458 850 24 the the DT 50458 850 25 bacilli bacilli NN 50458 850 26 it -PRON- PRP 50458 850 27 is be VBZ 50458 850 28 desired desire VBN 50458 850 29 to to TO 50458 850 30 use use VB 50458 850 31 . . . 50458 851 1 [ [ -LRB- 50458 851 2 110 110 CD 50458 851 3 ] ] -RRB- 50458 851 4 _ _ NNP 50458 851 5 Annal Annal NNP 50458 851 6 . . . 50458 852 1 de de NNP 50458 852 2 l'Instit l'Instit NNP 50458 852 3 . . . 50458 853 1 Pasteur Pasteur NNP 50458 853 2 _ _ NNP 50458 853 3 , , , 50458 853 4 II II NNP 50458 853 5 , , , 50458 853 6 p. p. NN 50458 853 7 632 632 CD 50458 853 8 , , , 50458 853 9 and and CC 50458 853 10 VIII VIII NNP 50458 853 11 , , , 50458 853 12 p. p. NN 50458 853 13 611 611 CD 50458 853 14 . . . 50458 854 1 [ [ -LRB- 50458 854 2 111 111 CD 50458 854 3 ] ] -RRB- 50458 854 4 See see VB 50458 854 5 SPRONK spronk NN 50458 854 6 : : : 50458 854 7 _ _ NNP 50458 854 8 Annal Annal NNP 50458 854 9 . . . 50458 855 1 de de NNP 50458 855 2 l'Instit l'Instit NNP 50458 855 3 . . . 50458 856 1 Pasteur Pasteur NNP 50458 856 2 _ _ NNP 50458 856 3 , , , 50458 856 4 IX IX NNP 50458 856 5 , , , 50458 856 6 p. p. NN 50458 856 7 785 785 CD 50458 856 8 ; ; : 50458 856 9 _ _ NNP 50458 856 10 Ibid Ibid NNP 50458 856 11 . . . 50458 856 12 _ _ NNP 50458 856 13 , , , 50458 856 14 X X NNP 50458 856 15 , , , 50458 856 16 p. p. NN 50458 856 17 333 333 CD 50458 856 18 ; ; : 50458 856 19 MARTIN MARTIN NNP 50458 856 20 , , , 50458 856 21 _ _ NNP 50458 856 22 Ibid Ibid NNP 50458 856 23 . . . 50458 856 24 _ _ NNP 50458 856 25 , , , 50458 856 26 XII XII NNP 50458 856 27 , , , 50458 856 28 p. p. NN 50458 856 29 26 26 CD 50458 856 30 ; ; : 50458 856 31 SPRONK SPRONK NNP 50458 856 32 , , , 50458 856 33 _ _ NNP 50458 856 34 Ibid Ibid NNP 50458 856 35 . . . 50458 856 36 _ _ NNP 50458 856 37 , , , 50458 856 38 XII XII NNP 50458 856 39 , , , 50458 856 40 p. p. NN 50458 856 41 711 711 CD 50458 856 42 . . . 50458 857 1 The the DT 50458 857 2 toxic toxic JJ 50458 857 3 liquid liquid NN 50458 857 4 obtained obtain VBN 50458 857 5 is be VBZ 50458 857 6 exceedingly exceedingly RB 50458 857 7 powerful powerful JJ 50458 857 8 : : : 50458 857 9 0.1 0.1 CD 50458 857 10 Cc Cc NNP 50458 857 11 . . . 50458 858 1 kills kill VBZ 50458 858 2 a a DT 50458 858 3 rabbit rabbit NN 50458 858 4 in in IN 50458 858 5 forty forty CD 50458 858 6 - - HYPH 50458 858 7 eight eight CD 50458 858 8 hours hour NNS 50458 858 9 . . . 50458 859 1 This this DT 50458 859 2 toxin toxin NN 50458 859 3 is be VBZ 50458 859 4 very very RB 50458 859 5 sensitive sensitive JJ 50458 859 6 to to IN 50458 859 7 the the DT 50458 859 8 effects effect NNS 50458 859 9 of of IN 50458 859 10 heat heat NN 50458 859 11 . . . 50458 860 1 When when WRB 50458 860 2 heated heat VBN 50458 860 3 to to IN 50458 860 4 65 65 CD 50458 860 5 ° ° , 50458 860 6 C. C. NNP 50458 860 7 it -PRON- PRP 50458 860 8 loses lose VBZ 50458 860 9 almost almost RB 50458 860 10 all all DT 50458 860 11 its -PRON- PRP$ 50458 860 12 toxicity toxicity NN 50458 860 13 ; ; : 50458 860 14 at at IN 50458 860 15 70º 70º CD 50458 860 16 C. C. NNP 50458 860 17 it -PRON- PRP 50458 860 18 becomes become VBZ 50458 860 19 innocuous innocuous JJ 50458 860 20 ; ; : 50458 860 21 and and CC 50458 860 22 it -PRON- PRP 50458 860 23 only only RB 50458 860 24 requires require VBZ 50458 860 25 to to TO 50458 860 26 be be VB 50458 860 27 heated heat VBN 50458 860 28 to to IN 50458 860 29 100 100 CD 50458 860 30 ° ° NNS 50458 860 31 C. C. NNP 50458 860 32 for for IN 50458 860 33 fifteen fifteen CD 50458 860 34 minutes minute NNS 50458 860 35 in in IN 50458 860 36 order order NN 50458 860 37 to to TO 50458 860 38 lose lose VB 50458 860 39 all all DT 50458 860 40 immediate immediate JJ 50458 860 41 activity activity NN 50458 860 42 even even RB 50458 860 43 in in IN 50458 860 44 large large JJ 50458 860 45 doses dose NNS 50458 860 46 . . . 50458 861 1 Nevertheless nevertheless RB 50458 861 2 toxins toxin NNS 50458 861 3 thus thus RB 50458 861 4 weakened weaken VBN 50458 861 5 are be VBP 50458 861 6 capable capable JJ 50458 861 7 of of IN 50458 861 8 proving prove VBG 50458 861 9 fatal fatal JJ 50458 861 10 to to IN 50458 861 11 an an DT 50458 861 12 animal animal NN 50458 861 13 even even RB 50458 861 14 after after IN 50458 861 15 five five CD 50458 861 16 or or CC 50458 861 17 six six CD 50458 861 18 months month NNS 50458 861 19 . . . 50458 862 1 Light light NN 50458 862 2 , , , 50458 862 3 oxygen oxygen NN 50458 862 4 , , , 50458 862 5 ozone ozone NN 50458 862 6 and and CC 50458 862 7 all all DT 50458 862 8 oxidizers oxidizer NNS 50458 862 9 destroy destroy VBP 50458 862 10 the the DT 50458 862 11 active active JJ 50458 862 12 principle principle NN 50458 862 13 of of IN 50458 862 14 the the DT 50458 862 15 diphtheria diphtheria NN 50458 862 16 toxin toxin NN 50458 862 17 , , , 50458 862 18 which which WDT 50458 862 19 is be VBZ 50458 862 20 , , , 50458 862 21 moreover moreover RB 50458 862 22 , , , 50458 862 23 rendered render VBN 50458 862 24 almost almost RB 50458 862 25 inactive inactive JJ 50458 862 26 by by IN 50458 862 27 organic organic JJ 50458 862 28 acids acid NNS 50458 862 29 . . . 50458 863 1 This this DT 50458 863 2 toxin toxin NN 50458 863 3 is be VBZ 50458 863 4 capable capable JJ 50458 863 5 of of IN 50458 863 6 diffusing diffuse VBG 50458 863 7 through through IN 50458 863 8 animal animal NN 50458 863 9 membranes membrane NNS 50458 863 10 , , , 50458 863 11 a a DT 50458 863 12 fact fact NN 50458 863 13 that that WDT 50458 863 14 is be VBZ 50458 863 15 in in IN 50458 863 16 agreement agreement NN 50458 863 17 with with IN 50458 863 18 the the DT 50458 863 19 toxic toxic JJ 50458 863 20 effect effect NN 50458 863 21 seen see VBN 50458 863 22 in in IN 50458 863 23 a a DT 50458 863 24 subject subject NN 50458 863 25 attacked attack VBN 50458 863 26 with with IN 50458 863 27 diphtheria diphtheria NN 50458 863 28 , , , 50458 863 29 and and CC 50458 863 30 due due IN 50458 863 31 to to IN 50458 863 32 the the DT 50458 863 33 toxin toxin NN 50458 863 34 passing pass VBG 50458 863 35 through through IN 50458 863 36 the the DT 50458 863 37 mucosa mucosa NNS 50458 863 38 . . . 50458 864 1 In in IN 50458 864 2 spite spite NN 50458 864 3 of of IN 50458 864 4 this this DT 50458 864 5 property property NN 50458 864 6 , , , 50458 864 7 however however RB 50458 864 8 , , , 50458 864 9 the the DT 50458 864 10 diphtheritic diphtheritic JJ 50458 864 11 poison poison NN 50458 864 12 may may MD 50458 864 13 be be VB 50458 864 14 taken take VBN 50458 864 15 into into IN 50458 864 16 the the DT 50458 864 17 stomach stomach NN 50458 864 18 without without IN 50458 864 19 any any DT 50458 864 20 pernicious pernicious JJ 50458 864 21 results result NNS 50458 864 22 . . . 50458 865 1 Roux Roux NNP 50458 865 2 and and CC 50458 865 3 Yersin Yersin NNP 50458 865 4 have have VBP 50458 865 5 shown show VBN 50458 865 6 that that IN 50458 865 7 , , , 50458 865 8 like like IN 50458 865 9 all all PDT 50458 865 10 the the DT 50458 865 11 diastases diastasis NNS 50458 865 12 , , , 50458 865 13 it -PRON- PRP 50458 865 14 may may MD 50458 865 15 be be VB 50458 865 16 precipitated precipitate VBN 50458 865 17 from from IN 50458 865 18 its -PRON- PRP$ 50458 865 19 solutions solution NNS 50458 865 20 by by IN 50458 865 21 the the DT 50458 865 22 development development NN 50458 865 23 , , , 50458 865 24 within within IN 50458 865 25 these these DT 50458 865 26 , , , 50458 865 27 of of IN 50458 865 28 certain certain JJ 50458 865 29 precipitates precipitate NNS 50458 865 30 , , , 50458 865 31 particularly particularly RB 50458 865 32 calcium calcium NN 50458 865 33 phosphate phosphate NN 50458 865 34 . . . 50458 866 1 It -PRON- PRP 50458 866 2 is be VBZ 50458 866 3 precipitated precipitate VBN 50458 866 4 from from IN 50458 866 5 its -PRON- PRP$ 50458 866 6 solutions solution NNS 50458 866 7 by by IN 50458 866 8 alcohol alcohol NN 50458 866 9 , , , 50458 866 10 as as IN 50458 866 11 has have VBZ 50458 866 12 been be VBN 50458 866 13 observed observe VBN 50458 866 14 also also RB 50458 866 15 in in IN 50458 866 16 the the DT 50458 866 17 case case NN 50458 866 18 of of IN 50458 866 19 diastatic diastatic JJ 50458 866 20 solutions solution NNS 50458 866 21 . . . 50458 867 1 All all PDT 50458 867 2 the the DT 50458 867 3 toxic toxic JJ 50458 867 4 substance substance NN 50458 867 5 is be VBZ 50458 867 6 contained contain VBN 50458 867 7 in in IN 50458 867 8 the the DT 50458 867 9 albuminous albuminous JJ 50458 867 10 precipitate precipitate NN 50458 867 11 thus thus RB 50458 867 12 obtained obtain VBN 50458 867 13 ; ; : 50458 867 14 but but CC 50458 867 15 the the DT 50458 867 16 prolonged prolonged JJ 50458 867 17 action action NN 50458 867 18 of of IN 50458 867 19 alcohol alcohol NN 50458 867 20 , , , 50458 867 21 or or CC 50458 867 22 repeated repeat VBN 50458 867 23 successive successive JJ 50458 867 24 precipitations precipitation NNS 50458 867 25 , , , 50458 867 26 alter alter VB 50458 867 27 it -PRON- PRP 50458 867 28 finally finally RB 50458 867 29 . . . 50458 868 1 Diphtheria diphtheria NN 50458 868 2 toxin toxin NN 50458 868 3 is be VBZ 50458 868 4 likewise likewise RB 50458 868 5 precipitated precipitate VBN 50458 868 6 by by IN 50458 868 7 the the DT 50458 868 8 reagents reagent NNS 50458 868 9 for for IN 50458 868 10 albumoses albumose NNS 50458 868 11 , , , 50458 868 12 particularly particularly RB 50458 868 13 sodium sodium NN 50458 868 14 sulphate sulphate NN 50458 868 15 in in IN 50458 868 16 saturated saturate VBN 50458 868 17 solution solution NN 50458 868 18 . . . 50458 869 1 This this DT 50458 869 2 procedure procedure NN 50458 869 3 has have VBZ 50458 869 4 been be VBN 50458 869 5 utilized utilize VBN 50458 869 6 by by IN 50458 869 7 Brieger Brieger NNP 50458 869 8 and and CC 50458 869 9 Fraenkel Fraenkel NNP 50458 869 10 for for IN 50458 869 11 preparing prepare VBG 50458 869 12 the the DT 50458 869 13 pure pure JJ 50458 869 14 toxin toxin NN 50458 869 15 , , , 50458 869 16 which which WDT 50458 869 17 they -PRON- PRP 50458 869 18 obtained obtain VBD 50458 869 19 in in IN 50458 869 20 the the DT 50458 869 21 form form NN 50458 869 22 of of IN 50458 869 23 very very RB 50458 869 24 light light JJ 50458 869 25 , , , 50458 869 26 brilliant brilliant JJ 50458 869 27 white white JJ 50458 869 28 , , , 50458 869 29 amorphous amorphous JJ 50458 869 30 flocks flock NNS 50458 869 31 , , , 50458 869 32 affording afford VBG 50458 869 33 all all PDT 50458 869 34 the the DT 50458 869 35 principal principal JJ 50458 869 36 reactions reaction NNS 50458 869 37 of of IN 50458 869 38 the the DT 50458 869 39 soluble soluble JJ 50458 869 40 albumoses albumose NNS 50458 869 41 ( ( -LRB- 50458 869 42 biuret biuret NN 50458 869 43 , , , 50458 869 44 xanthoproteic xanthoproteic NNP 50458 869 45 , , , 50458 869 46 Millon Millon NNP 50458 869 47 's 's POS 50458 869 48 ) ) -RRB- 50458 869 49 , , , 50458 869 50 and and CC 50458 869 51 which which WDT 50458 869 52 they -PRON- PRP 50458 869 53 characterized characterize VBD 50458 869 54 as as IN 50458 869 55 a a DT 50458 869 56 toxalbumin toxalbumin NN 50458 869 57 . . . 50458 870 1 On on IN 50458 870 2 injecting inject VBG 50458 870 3 into into IN 50458 870 4 healthy healthy JJ 50458 870 5 animals animal NNS 50458 870 6 this this DT 50458 870 7 diphtheria diphtheria NN 50458 870 8 toxin toxin NN 50458 870 9 attenuated attenuate VBN 50458 870 10 by by IN 50458 870 11 sufficiently sufficiently RB 50458 870 12 heating heat VBG 50458 870 13 at at IN 50458 870 14 70 70 CD 50458 870 15 ° ° , 50458 870 16 C C NNP 50458 870 17 , , , 50458 870 18 employing employ VBG 50458 870 19 at at IN 50458 870 20 first first JJ 50458 870 21 small small JJ 50458 870 22 doses dose NNS 50458 870 23 , , , 50458 870 24 and and CC 50458 870 25 gradually gradually RB 50458 870 26 increasing increase VBG 50458 870 27 , , , 50458 870 28 it -PRON- PRP 50458 870 29 is be VBZ 50458 870 30 possible possible JJ 50458 870 31 to to TO 50458 870 32 immunize immunize VB 50458 870 33 them -PRON- PRP 50458 870 34 against against IN 50458 870 35 diphtheria diphtheria NN 50458 870 36 , , , 50458 870 37 as as IN 50458 870 38 was be VBD 50458 870 39 first first RB 50458 870 40 demonstrated demonstrate VBN 50458 870 41 by by IN 50458 870 42 Carl Carl NNP 50458 870 43 Fraenkel Fraenkel NNP 50458 870 44 . . . 50458 871 1 Roux Roux NNP 50458 871 2 and and CC 50458 871 3 Martin Martin NNP 50458 871 4 , , , 50458 871 5 who who WP 50458 871 6 have have VBP 50458 871 7 specially specially RB 50458 871 8 studied study VBN 50458 871 9 this this DT 50458 871 10 procedure,[112 procedure,[112 NN 50458 871 11 ] ] -RRB- 50458 871 12 have have VBP 50458 871 13 shown show VBN 50458 871 14 that that IN 50458 871 15 a a DT 50458 871 16 horse horse NN 50458 871 17 may may MD 50458 871 18 be be VB 50458 871 19 easily easily RB 50458 871 20 immunized immunize VBN 50458 871 21 by by IN 50458 871 22 injecting inject VBG 50458 871 23 into into IN 50458 871 24 the the DT 50458 871 25 animal animal NN 50458 871 26 the the DT 50458 871 27 toxin toxin NN 50458 871 28 diluted dilute VBN 50458 871 29 with with IN 50458 871 30 a a DT 50458 871 31 third third NN 50458 871 32 of of IN 50458 871 33 its -PRON- PRP$ 50458 871 34 volume volume NN 50458 871 35 of of IN 50458 871 36 Gram Gram NNP 50458 871 37 's 's POS 50458 871 38 iodine iodine NN 50458 871 39 solution solution NN 50458 871 40 , , , 50458 871 41 and and CC 50458 871 42 in in IN 50458 871 43 successively successively RB 50458 871 44 increasing increase VBG 50458 871 45 doses dose NNS 50458 871 46 . . . 50458 872 1 The the DT 50458 872 2 initial initial JJ 50458 872 3 dose dose NN 50458 872 4 is be VBZ 50458 872 5 0.25 0.25 CD 50458 872 6 Cc Cc NNP 50458 872 7 . . . 50458 873 1 ; ; : 50458 873 2 then then RB 50458 873 3 , , , 50458 873 4 after after IN 50458 873 5 two two CD 50458 873 6 days day NNS 50458 873 7 , , , 50458 873 8 0.5 0.5 CD 50458 873 9 Cc Cc NNP 50458 873 10 . . . 50458 874 1 of of IN 50458 874 2 the the DT 50458 874 3 same same JJ 50458 874 4 toxin toxin NN 50458 874 5 is be VBZ 50458 874 6 injected inject VBN 50458 874 7 , , , 50458 874 8 and and CC 50458 874 9 in in IN 50458 874 10 like like NNP 50458 874 11 manner manner NN 50458 874 12 the the DT 50458 874 13 dose dose NN 50458 874 14 is be VBZ 50458 874 15 increased increase VBN 50458 874 16 up up IN 50458 874 17 to to IN 50458 874 18 the the DT 50458 874 19 eighteenth eighteenth JJ 50458 874 20 day day NN 50458 874 21 , , , 50458 874 22 when when WRB 50458 874 23 the the DT 50458 874 24 pure pure JJ 50458 874 25 toxin toxin NN 50458 874 26 is be VBZ 50458 874 27 injected inject VBN 50458 874 28 , , , 50458 874 29 at at IN 50458 874 30 first first RB 50458 874 31 in in IN 50458 874 32 small small JJ 50458 874 33 doses dose NNS 50458 874 34 , , , 50458 874 35 which which WDT 50458 874 36 are be VBP 50458 874 37 gradually gradually RB 50458 874 38 increased increase VBN 50458 874 39 so so IN 50458 874 40 that that IN 50458 874 41 at at IN 50458 874 42 the the DT 50458 874 43 end end NN 50458 874 44 of of IN 50458 874 45 two two CD 50458 874 46 or or CC 50458 874 47 three three CD 50458 874 48 months month NNS 50458 874 49 injections injection NNS 50458 874 50 of of IN 50458 874 51 80 80 CD 50458 874 52 Cc Cc NNP 50458 874 53 . . . 50458 875 1 of of IN 50458 875 2 the the DT 50458 875 3 pure pure JJ 50458 875 4 toxin toxin NN 50458 875 5 may may MD 50458 875 6 be be VB 50458 875 7 given give VBN 50458 875 8 without without IN 50458 875 9 danger danger NN 50458 875 10 ; ; : 50458 875 11 the the DT 50458 875 12 animal animal NN 50458 875 13 is be VBZ 50458 875 14 then then RB 50458 875 15 completely completely RB 50458 875 16 immunized immunized JJ 50458 875 17 . . . 50458 876 1 [ [ -LRB- 50458 876 2 112 112 CD 50458 876 3 ] ] -RRB- 50458 876 4 Contribution Contribution NNP 50458 876 5 à à NNP 50458 876 6 l'Étude l'Étude NNP 50458 876 7 de de NNP 50458 876 8 la la NNP 50458 876 9 Diphtérie Diphtérie NNP 50458 876 10 . . . 50458 877 1 _ _ NNP 50458 877 2 Annal Annal NNP 50458 877 3 . . . 50458 878 1 de de NNP 50458 878 2 l'Instit l'Instit NNP 50458 878 3 . . . 50458 879 1 Pasteur Pasteur NNP 50458 879 2 _ _ NNP 50458 879 3 , , , 50458 879 4 VIII VIII NNP 50458 879 5 , , , 50458 879 6 p. p. NN 50458 879 7 609 609 CD 50458 879 8 ; ; : 50458 879 9 _ _ NNP 50458 879 10 Ibid Ibid NNP 50458 879 11 . . . 50458 879 12 _ _ NNP 50458 879 13 , , , 50458 879 14 p. p. NN 50458 879 15 640 640 CD 50458 879 16 . . . 50458 880 1 The the DT 50458 880 2 serum serum NN 50458 880 3 of of IN 50458 880 4 an an DT 50458 880 5 animal animal NN 50458 880 6 rendered render VBN 50458 880 7 immune immune JJ 50458 880 8 in in IN 50458 880 9 this this DT 50458 880 10 manner manner NN 50458 880 11 contains contain VBZ 50458 880 12 a a DT 50458 880 13 diphtheria diphtheria NN 50458 880 14 antitoxin antitoxin NN 50458 880 15 which which WDT 50458 880 16 possesses possess VBZ 50458 880 17 high high JJ 50458 880 18 power power NN 50458 880 19 . . . 50458 881 1 A a DT 50458 881 2 guinea guinea NN 50458 881 3 - - HYPH 50458 881 4 pig pig NN 50458 881 5 which which WDT 50458 881 6 has have VBZ 50458 881 7 received receive VBN 50458 881 8 an an DT 50458 881 9 injection injection NN 50458 881 10 of of IN 50458 881 11 0.01 0.01 CD 50458 881 12 Cc Cc NNP 50458 881 13 . . . 50458 882 1 of of IN 50458 882 2 the the DT 50458 882 3 antitoxin antitoxin NN 50458 882 4 is be VBZ 50458 882 5 perfectly perfectly RB 50458 882 6 capable capable JJ 50458 882 7 of of IN 50458 882 8 withstanding withstand VBG 50458 882 9 a a DT 50458 882 10 lethal lethal JJ 50458 882 11 dose dose NN 50458 882 12 of of IN 50458 882 13 0.5 0.5 CD 50458 882 14 Cc Cc NNP 50458 882 15 . . . 50458 883 1 of of IN 50458 883 2 the the DT 50458 883 3 toxin toxin NN 50458 883 4 . . . 50458 884 1 The the DT 50458 884 2 antidiphtheria antidiphtheria NN 50458 884 3 serum serum NN 50458 884 4 thus thus RB 50458 884 5 obtained obtain VBN 50458 884 6 , , , 50458 884 7 and and CC 50458 884 8 in in IN 50458 884 9 almost almost RB 50458 884 10 limitless limitless JJ 50458 884 11 quantities quantity NNS 50458 884 12 , , , 50458 884 13 from from IN 50458 884 14 an an DT 50458 884 15 immunized immunized JJ 50458 884 16 animal animal NN 50458 884 17 , , , 50458 884 18 is be VBZ 50458 884 19 capable capable JJ 50458 884 20 of of IN 50458 884 21 saturating saturate VBG 50458 884 22 the the DT 50458 884 23 therapeutic therapeutic JJ 50458 884 24 diphtheritic diphtheritic JJ 50458 884 25 toxin toxin NN 50458 884 26 , , , 50458 884 27 and and CC 50458 884 28 has have VBZ 50458 884 29 to to IN 50458 884 30 - - HYPH 50458 884 31 day day NN 50458 884 32 taken take VBN 50458 884 33 rank rank NN 50458 884 34 in in IN 50458 884 35 therapeutics therapeutic NNS 50458 884 36 as as IN 50458 884 37 the the DT 50458 884 38 most most RBS 50458 884 39 efficacious efficacious JJ 50458 884 40 remedy remedy NN 50458 884 41 in in IN 50458 884 42 diphtheria diphtheria NN 50458 884 43 . . . 50458 885 1 Injected inject VBN 50458 885 2 in in IN 50458 885 3 varying vary VBG 50458 885 4 doses dose NNS 50458 885 5 , , , 50458 885 6 it -PRON- PRP 50458 885 7 confers confer VBZ 50458 885 8 a a DT 50458 885 9 temporary temporary JJ 50458 885 10 but but CC 50458 885 11 immediate immediate JJ 50458 885 12 immunity immunity NN 50458 885 13 . . . 50458 886 1 Nevertheless nevertheless RB 50458 886 2 antidiphtheria antidiphtheria NN 50458 886 3 serum serum NN 50458 886 4 must must MD 50458 886 5 not not RB 50458 886 6 be be VB 50458 886 7 considered consider VBN 50458 886 8 as as IN 50458 886 9 an an DT 50458 886 10 antidote antidote NN 50458 886 11 ; ; : 50458 886 12 and and CC 50458 886 13 in in IN 50458 886 14 pathological pathological JJ 50458 886 15 diphtheria diphtheria NN 50458 886 16 , , , 50458 886 17 the the DT 50458 886 18 more more JJR 50458 886 19 serum serum NN 50458 886 20 is be VBZ 50458 886 21 required require VBN 50458 886 22 the the DT 50458 886 23 later later JJ 50458 886 24 it -PRON- PRP 50458 886 25 is be VBZ 50458 886 26 used use VBN 50458 886 27 . . . 50458 887 1 [ [ -LRB- 50458 887 2 113 113 CD 50458 887 3 ] ] -RRB- 50458 887 4 In in IN 50458 887 5 certain certain JJ 50458 887 6 cases case NNS 50458 887 7 , , , 50458 887 8 if if IN 50458 887 9 employed employ VBN 50458 887 10 too too RB 50458 887 11 late late RB 50458 887 12 , , , 50458 887 13 it -PRON- PRP 50458 887 14 may may MD 50458 887 15 prove prove VB 50458 887 16 ineffective ineffective JJ 50458 887 17 . . . 50458 888 1 [ [ -LRB- 50458 888 2 113 113 CD 50458 888 3 ] ] -RRB- 50458 888 4 BAYEUX BAYEUX NNP 50458 888 5 : : : 50458 888 6 _ _ NNP 50458 888 7 Thèse Thèse NNP 50458 888 8 de de NNP 50458 888 9 Doctorat Doctorat NNP 50458 888 10 _ _ NNP 50458 888 11 , , , 50458 888 12 Paris Paris NNP 50458 888 13 , , , 50458 888 14 1899 1899 CD 50458 888 15 . . . 50458 889 1 The the DT 50458 889 2 preventive preventive JJ 50458 889 3 action action NN 50458 889 4 of of IN 50458 889 5 the the DT 50458 889 6 serum serum NN 50458 889 7 is be VBZ 50458 889 8 remarkable remarkable JJ 50458 889 9 . . . 50458 890 1 In in IN 50458 890 2 10 10 CD 50458 890 3 000 000 CD 50458 890 4 inoculated inoculate VBN 50458 890 5 cases case NNS 50458 890 6 Behring behre VBG 50458 890 7 and and CC 50458 890 8 Ehrlich Ehrlich NNP 50458 890 9 have have VBP 50458 890 10 had have VBN 50458 890 11 but but CC 50458 890 12 10 10 CD 50458 890 13 cases case NNS 50458 890 14 of of IN 50458 890 15 diphtheria diphtheria NN 50458 890 16 , , , 50458 890 17 and and CC 50458 890 18 these these DT 50458 890 19 were be VBD 50458 890 20 , , , 50458 890 21 moreover moreover RB 50458 890 22 , , , 50458 890 23 of of IN 50458 890 24 a a DT 50458 890 25 benign benign JJ 50458 890 26 character character NN 50458 890 27 . . . 50458 891 1 The the DT 50458 891 2 duration duration NN 50458 891 3 of of IN 50458 891 4 the the DT 50458 891 5 immunizing immunize VBG 50458 891 6 action action NN 50458 891 7 appears appear VBZ 50458 891 8 to to TO 50458 891 9 be be VB 50458 891 10 from from IN 50458 891 11 three three CD 50458 891 12 weeks week NNS 50458 891 13 to to IN 50458 891 14 two two CD 50458 891 15 months month NNS 50458 891 16 . . . 50458 892 1 This this DT 50458 892 2 diphtheria diphtheria NN 50458 892 3 antitoxin antitoxin NN 50458 892 4 was be VBD 50458 892 5 first first RB 50458 892 6 prepared prepare VBN 50458 892 7 by by IN 50458 892 8 Guérin Guérin NNP 50458 892 9 and and CC 50458 892 10 Macé[114 macé[114 CD 50458 892 11 ] ] -RRB- 50458 892 12 by by IN 50458 892 13 adding add VBG 50458 892 14 to to IN 50458 892 15 the the DT 50458 892 16 antidiphtheria antidiphtheria NN 50458 892 17 serum serum NN 50458 892 18 a a DT 50458 892 19 large large JJ 50458 892 20 volume volume NN 50458 892 21 of of IN 50458 892 22 alcohol alcohol NN 50458 892 23 , , , 50458 892 24 washing wash VBG 50458 892 25 the the DT 50458 892 26 precipitate precipitate NN 50458 892 27 , , , 50458 892 28 and and CC 50458 892 29 drying dry VBG 50458 892 30 it -PRON- PRP 50458 892 31 in in IN 50458 892 32 a a DT 50458 892 33 vacuum vacuum NN 50458 892 34 . . . 50458 893 1 It -PRON- PRP 50458 893 2 is be VBZ 50458 893 3 soluble soluble JJ 50458 893 4 in in IN 50458 893 5 water water NN 50458 893 6 , , , 50458 893 7 and and CC 50458 893 8 loses lose VBZ 50458 893 9 its -PRON- PRP$ 50458 893 10 activity activity NN 50458 893 11 when when WRB 50458 893 12 heated heat VBN 50458 893 13 to to IN 50458 893 14 65 65 CD 50458 893 15 ° ° , 50458 893 16 C. C. NNP 50458 893 17 Wassermann[115 Wassermann[115 NNP 50458 893 18 ] ] -RRB- 50458 893 19 has have VBZ 50458 893 20 proposed propose VBN 50458 893 21 to to TO 50458 893 22 extract extract VB 50458 893 23 it -PRON- PRP 50458 893 24 from from IN 50458 893 25 the the DT 50458 893 26 milk milk NN 50458 893 27 of of IN 50458 893 28 immunized immunized JJ 50458 893 29 animals animal NNS 50458 893 30 , , , 50458 893 31 by by IN 50458 893 32 first first RB 50458 893 33 coagulating coagulate VBG 50458 893 34 the the DT 50458 893 35 milk milk NN 50458 893 36 by by IN 50458 893 37 rennet rennet NN 50458 893 38 in in IN 50458 893 39 the the DT 50458 893 40 presence presence NN 50458 893 41 of of IN 50458 893 42 sodium sodium NN 50458 893 43 chloride chloride NN 50458 893 44 , , , 50458 893 45 filtering filtering NN 50458 893 46 , , , 50458 893 47 and and CC 50458 893 48 removing remove VBG 50458 893 49 the the DT 50458 893 50 fat fat NN 50458 893 51 from from IN 50458 893 52 the the DT 50458 893 53 clear clear JJ 50458 893 54 liquid liquid NN 50458 893 55 by by IN 50458 893 56 means mean NNS 50458 893 57 of of IN 50458 893 58 chloroform chloroform NN 50458 893 59 . . . 50458 894 1 After after IN 50458 894 2 decanting decant VBG 50458 894 3 , , , 50458 894 4 the the DT 50458 894 5 clear clear JJ 50458 894 6 solution solution NN 50458 894 7 obtained obtain VBN 50458 894 8 is be VBZ 50458 894 9 precipitated precipitate VBN 50458 894 10 by by IN 50458 894 11 adding add VBG 50458 894 12 to to IN 50458 894 13 it -PRON- PRP 50458 894 14 30 30 CD 50458 894 15 to to TO 50458 894 16 33 33 CD 50458 894 17 per per NN 50458 894 18 cent cent NN 50458 894 19 . . . 50458 895 1 of of IN 50458 895 2 ammonium ammonium NN 50458 895 3 sulphate sulphate NN 50458 895 4 . . . 50458 896 1 The the DT 50458 896 2 precipitate precipitate NN 50458 896 3 is be VBZ 50458 896 4 dried dry VBN 50458 896 5 in in IN 50458 896 6 a a DT 50458 896 7 vacuum vacuum NN 50458 896 8 on on IN 50458 896 9 a a DT 50458 896 10 polished polished JJ 50458 896 11 porcelain porcelain NN 50458 896 12 slab slab NN 50458 896 13 after after IN 50458 896 14 having have VBG 50458 896 15 first first RB 50458 896 16 been be VBN 50458 896 17 strongly strongly RB 50458 896 18 expressed express VBN 50458 896 19 . . . 50458 897 1 It -PRON- PRP 50458 897 2 is be VBZ 50458 897 3 then then RB 50458 897 4 dissolved dissolve VBN 50458 897 5 in in IN 50458 897 6 water water NN 50458 897 7 . . . 50458 898 1 [ [ -LRB- 50458 898 2 116 116 CD 50458 898 3 ] ] -RRB- 50458 898 4 [ [ -LRB- 50458 898 5 114 114 CD 50458 898 6 ] ] -RRB- 50458 898 7 _ _ NNP 50458 898 8 Compt Compt NNP 50458 898 9 . . . 50458 899 1 rend rend VB 50458 899 2 . . . 50458 900 1 de de NNP 50458 900 2 l'Acad l'Acad NNP 50458 900 3 . . . 50458 901 1 des des NNP 50458 901 2 Sc Sc NNP 50458 901 3 . . . 50458 901 4 _ _ NNP 50458 901 5 , , , 50458 901 6 Apr. April NNP 50458 902 1 5 5 CD 50458 902 2 , , , 50458 902 3 1895 1895 CD 50458 902 4 . . . 50458 903 1 [ [ -LRB- 50458 903 2 115 115 CD 50458 903 3 ] ] -RRB- 50458 903 4 _ _ NNP 50458 903 5 Zeitschr Zeitschr NNP 50458 903 6 . . . 50458 904 1 für für NNP 50458 904 2 Hygiene Hygiene NNP 50458 904 3 _ _ NNP 50458 904 4 , , , 50458 904 5 XVIII XVIII NNP 50458 904 6 , , , 50458 904 7 p. p. NN 50458 904 8 235 235 CD 50458 904 9 . . . 50458 905 1 [ [ -LRB- 50458 905 2 116 116 CD 50458 905 3 ] ] -RRB- 50458 905 4 ROUX ROUX NNS 50458 905 5 and and CC 50458 905 6 MARTIN MARTIN NNP 50458 905 7 : : : 50458 905 8 Contribution Contribution NNP 50458 905 9 à à NNP 50458 905 10 l'Étude l'Étude NNP 50458 905 11 de de NNP 50458 905 12 la la NNP 50458 905 13 Diphtérie Diphtérie NNP 50458 905 14 . . . 50458 906 1 _ _ NNP 50458 906 2 Annal Annal NNP 50458 906 3 . . . 50458 907 1 de de NNP 50458 907 2 l'Instit l'Instit NNP 50458 907 3 . . . 50458 908 1 Pasteur Pasteur NNP 50458 908 2 _ _ NNP 50458 908 3 , , , 50458 908 4 VIII VIII NNP 50458 908 5 , , , 50458 908 6 p. p. NN 50458 908 7 512 512 CD 50458 908 8 . . . 50458 909 1 = = NFP 50458 909 2 Tetanus tetanus NN 50458 909 3 Toxin.=--The Toxin.=--The NNP 50458 909 4 fact fact NN 50458 909 5 that that IN 50458 909 6 the the DT 50458 909 7 tetanus tetanus JJ 50458 909 8 bacillus bacillus NN 50458 909 9 never never RB 50458 909 10 penetrates penetrate VBZ 50458 909 11 to to IN 50458 909 12 the the DT 50458 909 13 interior interior NN 50458 909 14 of of IN 50458 909 15 the the DT 50458 909 16 organism organism NN 50458 909 17 enabled enable VBD 50458 909 18 us -PRON- PRP 50458 909 19 long long RB 50458 909 20 ago ago RB 50458 909 21 to to TO 50458 909 22 foretell foretell VB 50458 909 23 that that IN 50458 909 24 it -PRON- PRP 50458 909 25 secretes secrete VBZ 50458 909 26 a a DT 50458 909 27 very very RB 50458 909 28 powerful powerful JJ 50458 909 29 toxin toxin NN 50458 909 30 capable capable JJ 50458 909 31 of of IN 50458 909 32 dialyzing dialyze VBG 50458 909 33 and and CC 50458 909 34 diffusing diffuse VBG 50458 909 35 through through IN 50458 909 36 the the DT 50458 909 37 economy economy NN 50458 909 38 . . . 50458 910 1 Kuno Kuno NNP 50458 910 2 Faber Faber NNP 50458 910 3 was be VBD 50458 910 4 the the DT 50458 910 5 first first JJ 50458 910 6 to to TO 50458 910 7 fully fully RB 50458 910 8 recognize recognize VB 50458 910 9 the the DT 50458 910 10 fact fact NN 50458 910 11 that that IN 50458 910 12 the the DT 50458 910 13 culture culture NN 50458 910 14 bouillon bouillon NN 50458 910 15 of of IN 50458 910 16 this this DT 50458 910 17 bacillus bacillus NN 50458 910 18 , , , 50458 910 19 fully fully RB 50458 910 20 sterilized sterilize VBN 50458 910 21 by by IN 50458 910 22 filtration filtration NN 50458 910 23 through through IN 50458 910 24 porcelain porcelain NN 50458 910 25 , , , 50458 910 26 possesses possess VBZ 50458 910 27 an an DT 50458 910 28 exceedingly exceedingly RB 50458 910 29 high high JJ 50458 910 30 toxicity toxicity NN 50458 910 31 , , , 50458 910 32 and and CC 50458 910 33 exerts exert VBZ 50458 910 34 a a DT 50458 910 35 toxic toxic JJ 50458 910 36 effect effect NN 50458 910 37 on on IN 50458 910 38 50 50 CD 50458 910 39 000 000 CD 50458 910 40 000 000 CD 50458 910 41 times time NNS 50458 910 42 its -PRON- PRP$ 50458 910 43 own own JJ 50458 910 44 weight weight NN 50458 910 45 of of IN 50458 910 46 living living NN 50458 910 47 organism organism NN 50458 910 48 . . . 50458 911 1 Brieger Brieger NNP 50458 911 2 had have VBD 50458 911 3 previously previously RB 50458 911 4 , , , 50458 911 5 however however RB 50458 911 6 , , , 50458 911 7 extracted extract VBD 50458 911 8 three three CD 50458 911 9 ptomaines ptomaine NNS 50458 911 10 from from IN 50458 911 11 the the DT 50458 911 12 cultures culture NNS 50458 911 13 of of IN 50458 911 14 the the DT 50458 911 15 bacillus--_tetanin bacillus--_tetanin NNP 50458 911 16 _ _ NNP 50458 911 17 , , , 50458 911 18 _ _ NNP 50458 911 19 tetanotoxin tetanotoxin NN 50458 911 20 _ _ NNP 50458 911 21 , , , 50458 911 22 and and CC 50458 911 23 _ _ NNP 50458 911 24 spasmotoxin spasmotoxin NN 50458 911 25 _ _ NNP 50458 911 26 . . . 50458 912 1 [ [ -LRB- 50458 912 2 117 117 CD 50458 912 3 ] ] -RRB- 50458 912 4 In in IN 50458 912 5 order order NN 50458 912 6 to to TO 50458 912 7 obtain obtain VB 50458 912 8 a a DT 50458 912 9 highly highly RB 50458 912 10 active active JJ 50458 912 11 liquid liquid NN 50458 912 12 , , , 50458 912 13 the the DT 50458 912 14 same same JJ 50458 912 15 culture culture NN 50458 912 16 medium medium NN 50458 912 17 is be VBZ 50458 912 18 inoculated inoculate VBN 50458 912 19 several several JJ 50458 912 20 times time NNS 50458 912 21 in in IN 50458 912 22 succession succession NN 50458 912 23 , , , 50458 912 24 but but CC 50458 912 25 filtering filter VBG 50458 912 26 each each DT 50458 912 27 time time NN 50458 912 28 before before IN 50458 912 29 the the DT 50458 912 30 new new JJ 50458 912 31 inoculation inoculation NN 50458 912 32 ; ; : 50458 912 33 the the DT 50458 912 34 microbes microbe NNS 50458 912 35 greatly greatly RB 50458 912 36 increase increase VBP 50458 912 37 in in IN 50458 912 38 number number NN 50458 912 39 after after IN 50458 912 40 each each DT 50458 912 41 fresh fresh JJ 50458 912 42 inoculation inoculation NN 50458 912 43 , , , 50458 912 44 and and CC 50458 912 45 the the DT 50458 912 46 toxic toxic JJ 50458 912 47 substance substance NN 50458 912 48 developed develop VBN 50458 912 49 by by IN 50458 912 50 them -PRON- PRP 50458 912 51 accumulates accumulate NNS 50458 912 52 . . . 50458 913 1 [ [ -LRB- 50458 913 2 118 118 CD 50458 913 3 ] ] -RRB- 50458 913 4 [ [ -LRB- 50458 913 5 117 117 CD 50458 913 6 ] ] -RRB- 50458 913 7 Die die VB 50458 913 8 Pathogenese pathogenese JJ 50458 913 9 des des NN 50458 913 10 Tetanus Tetanus NNP 50458 913 11 . . . 50458 914 1 _ _ NNP 50458 914 2 Berlin Berlin NNP 50458 914 3 . . . 50458 915 1 Klin Klin NNP 50458 915 2 . . . 50458 916 1 Wochenschr Wochenschr NNP 50458 916 2 . . . 50458 916 3 _ _ NNP 50458 916 4 , , , 50458 916 5 1890 1890 CD 50458 916 6 , , , 50458 916 7 No no UH 50458 916 8 . . . 50458 917 1 31 31 CD 50458 917 2 . . . 50458 918 1 [ [ -LRB- 50458 918 2 118 118 CD 50458 918 3 ] ] -RRB- 50458 918 4 NAILLARD NAILLARD NNP 50458 918 5 : : : 50458 918 6 _ _ NNP 50458 918 7 Compt Compt NNP 50458 918 8 . . . 50458 919 1 rend rend VB 50458 919 2 . . . 50458 920 1 de de NNP 50458 920 2 l'Acad l'Acad NNP 50458 920 3 . . . 50458 921 1 des des NNP 50458 921 2 Sciences Sciences NNPS 50458 921 3 _ _ NNP 50458 921 4 , , , 50458 921 5 CXX CXX NNP 50458 921 6 , , , 50458 921 7 p. p. NN 50458 921 8 1181 1181 CD 50458 921 9 . . . 50458 922 1 Experiment experiment NN 50458 922 2 has have VBZ 50458 922 3 shown show VBN 50458 922 4 that that IN 50458 922 5 the the DT 50458 922 6 culture culture NN 50458 922 7 bouillon bouillon NN 50458 922 8 thus thus RB 50458 922 9 obtained obtain VBD 50458 922 10 contains contain VBZ 50458 922 11 two two CD 50458 922 12 kinds kind NNS 50458 922 13 of of IN 50458 922 14 toxic toxic JJ 50458 922 15 substances[119]--highly substances[119]--highly NNP 50458 922 16 toxic toxic JJ 50458 922 17 alkaloidal alkaloidal NN 50458 922 18 bases basis NNS 50458 922 19 ( ( -LRB- 50458 922 20 ptomaines ptomaine NNS 50458 922 21 , , , 50458 922 22 tetanin tetanin NNS 50458 922 23 , , , 50458 922 24 tetanotoxin tetanotoxin NN 50458 922 25 , , , 50458 922 26 etc etc FW 50458 922 27 . . . 50458 923 1 ) ) -RRB- 50458 923 2 , , , 50458 923 3 and and CC 50458 923 4 a a DT 50458 923 5 true true JJ 50458 923 6 toxin toxin NN 50458 923 7 , , , 50458 923 8 possessing possess VBG 50458 923 9 diastatic diastatic JJ 50458 923 10 properties property NNS 50458 923 11 , , , 50458 923 12 and and CC 50458 923 13 of of IN 50458 923 14 almost almost RB 50458 923 15 incredible incredible JJ 50458 923 16 toxic toxic JJ 50458 923 17 power power NN 50458 923 18 . . . 50458 924 1 [ [ -LRB- 50458 924 2 119 119 CD 50458 924 3 ] ] -RRB- 50458 924 4 _ _ NNP 50458 924 5 Annal Annal NNP 50458 924 6 . . . 50458 925 1 Instit Instit NNP 50458 925 2 . . . 50458 926 1 Pasteur Pasteur NNP 50458 926 2 _ _ NNP 50458 926 3 , , , 50458 926 4 V V NNP 50458 926 5 , , , 50458 926 6 15 15 CD 50458 926 7 . . . 50458 927 1 This this DT 50458 927 2 toxin toxin NN 50458 927 3 had have VBD 50458 927 4 already already RB 50458 927 5 been be VBN 50458 927 6 isolated isolate VBN 50458 927 7 by by IN 50458 927 8 Kitasato Kitasato NNP 50458 927 9 . . . 50458 928 1 It -PRON- PRP 50458 928 2 is be VBZ 50458 928 3 a a DT 50458 928 4 toxalbumin toxalbumin NN 50458 928 5 , , , 50458 928 6 and and CC 50458 928 7 is be VBZ 50458 928 8 very very RB 50458 928 9 sensitive sensitive JJ 50458 928 10 to to IN 50458 928 11 the the DT 50458 928 12 action action NN 50458 928 13 of of IN 50458 928 14 heat heat NN 50458 928 15 . . . 50458 929 1 A a DT 50458 929 2 temperature temperature NN 50458 929 3 of of IN 50458 929 4 65 65 CD 50458 929 5 ° ° , 50458 929 6 C. C. NNP 50458 929 7 , , , 50458 929 8 maintained maintain VBD 50458 929 9 for for IN 50458 929 10 30 30 CD 50458 929 11 minutes minute NNS 50458 929 12 , , , 50458 929 13 renders render VBZ 50458 929 14 it -PRON- PRP 50458 929 15 quite quite RB 50458 929 16 inactive inactive JJ 50458 929 17 ; ; : 50458 929 18 and and CC 50458 929 19 it -PRON- PRP 50458 929 20 becomes become VBZ 50458 929 21 oxidized oxidized JJ 50458 929 22 and and CC 50458 929 23 is be VBZ 50458 929 24 destroyed destroy VBN 50458 929 25 by by IN 50458 929 26 the the DT 50458 929 27 action action NN 50458 929 28 of of IN 50458 929 29 the the DT 50458 929 30 air air NN 50458 929 31 in in IN 50458 929 32 the the DT 50458 929 33 presence presence NN 50458 929 34 of of IN 50458 929 35 light light NN 50458 929 36 . . . 50458 930 1 Brieger Brieger NNP 50458 930 2 and and CC 50458 930 3 Boer,[120 Boer,[120 NNP 50458 930 4 ] ] -RRB- 50458 930 5 by by IN 50458 930 6 precipitating precipitate VBG 50458 930 7 with with IN 50458 930 8 zinc zinc NN 50458 930 9 chloride chloride NN 50458 930 10 the the DT 50458 930 11 filtered filter VBN 50458 930 12 culture culture NN 50458 930 13 bouillon bouillon NN 50458 930 14 , , , 50458 930 15 obtained obtain VBD 50458 930 16 a a DT 50458 930 17 pure pure JJ 50458 930 18 , , , 50458 930 19 amorphous amorphous JJ 50458 930 20 tetanus tetanus NN 50458 930 21 toxin toxin NN 50458 930 22 , , , 50458 930 23 which which WDT 50458 930 24 they -PRON- PRP 50458 930 25 also also RB 50458 930 26 considered consider VBD 50458 930 27 as as IN 50458 930 28 a a DT 50458 930 29 toxalbumin toxalbumin NN 50458 930 30 , , , 50458 930 31 and and CC 50458 930 32 which which WDT 50458 930 33 possesses possess VBZ 50458 930 34 exceedingly exceedingly RB 50458 930 35 toxic toxic JJ 50458 930 36 properties property NNS 50458 930 37 . . . 50458 931 1 [ [ -LRB- 50458 931 2 120 120 CD 50458 931 3 ] ] -RRB- 50458 931 4 _ _ NNP 50458 931 5 Deutsche Deutsche NNP 50458 931 6 Med Med NNP 50458 931 7 . . . 50458 932 1 Wochenschr Wochenschr NNP 50458 932 2 . . . 50458 932 3 _ _ NNP 50458 932 4 , , , 50458 932 5 No no UH 50458 932 6 . . . 50458 933 1 49 49 CD 50458 933 2 , , , 50458 933 3 Dec. December NNP 50458 933 4 3 3 CD 50458 933 5 , , , 50458 933 6 1896 1896 CD 50458 933 7 . . . 50458 934 1 If if IN 50458 934 2 a a DT 50458 934 3 precipitate precipitate NN 50458 934 4 be be VB 50458 934 5 caused cause VBN 50458 934 6 to to TO 50458 934 7 form form VB 50458 934 8 in in IN 50458 934 9 these these DT 50458 934 10 toxic toxic JJ 50458 934 11 solutions solution NNS 50458 934 12 , , , 50458 934 13 as as IN 50458 934 14 , , , 50458 934 15 for for IN 50458 934 16 instance instance NN 50458 934 17 , , , 50458 934 18 a a DT 50458 934 19 precipitate precipitate NN 50458 934 20 of of IN 50458 934 21 calcium calcium NN 50458 934 22 phosphate phosphate NN 50458 934 23 , , , 50458 934 24 this this DT 50458 934 25 carries carry VBZ 50458 934 26 down down RP 50458 934 27 with with IN 50458 934 28 it -PRON- PRP 50458 934 29 all all PDT 50458 934 30 the the DT 50458 934 31 toxin toxin NN 50458 934 32 present present JJ 50458 934 33 in in IN 50458 934 34 the the DT 50458 934 35 liquid liquid NN 50458 934 36 . . . 50458 935 1 0.0005 0.0005 NNP 50458 935 2 Gm Gm NNP 50458 935 3 . . . 50458 936 1 of of IN 50458 936 2 this this DT 50458 936 3 precipitate precipitate NN 50458 936 4 is be VBZ 50458 936 5 surely surely RB 50458 936 6 fatal fatal JJ 50458 936 7 to to IN 50458 936 8 a a DT 50458 936 9 guinea guinea NN 50458 936 10 - - HYPH 50458 936 11 pig pig NN 50458 936 12 . . . 50458 937 1 Dozon Dozon NNP 50458 937 2 and and CC 50458 937 3 Cournemont Cournemont NNP 50458 937 4 have have VBP 50458 937 5 observed observe VBN 50458 937 6 that that IN 50458 937 7 even even RB 50458 937 8 in in IN 50458 937 9 doses dose NNS 50458 937 10 of of IN 50458 937 11 300 300 CD 50458 937 12 to to TO 50458 937 13 400 400 CD 50458 937 14 Gm Gm NNP 50458 937 15 . . . 50458 938 1 of of IN 50458 938 2 the the DT 50458 938 3 filtered filter VBN 50458 938 4 culture culture NN 50458 938 5 liquid liquid NN 50458 938 6 , , , 50458 938 7 this this DT 50458 938 8 toxin toxin NN 50458 938 9 is be VBZ 50458 938 10 not not RB 50458 938 11 immediately immediately RB 50458 938 12 toxic toxic JJ 50458 938 13 to to IN 50458 938 14 a a DT 50458 938 15 horse horse NN 50458 938 16 , , , 50458 938 17 but but CC 50458 938 18 kills kill VBZ 50458 938 19 the the DT 50458 938 20 animal animal NN 50458 938 21 only only RB 50458 938 22 after after IN 50458 938 23 a a DT 50458 938 24 period period NN 50458 938 25 of of IN 50458 938 26 incubation incubation NN 50458 938 27 of of IN 50458 938 28 at at IN 50458 938 29 least least JJS 50458 938 30 twenty twenty CD 50458 938 31 - - HYPH 50458 938 32 four four CD 50458 938 33 hours hour NNS 50458 938 34 . . . 50458 939 1 The the DT 50458 939 2 blood blood NN 50458 939 3 of of IN 50458 939 4 such such PDT 50458 939 5 an an DT 50458 939 6 animal animal NN 50458 939 7 , , , 50458 939 8 however however RB 50458 939 9 , , , 50458 939 10 is be VBZ 50458 939 11 immediately immediately RB 50458 939 12 and and CC 50458 939 13 directly directly RB 50458 939 14 fatal fatal JJ 50458 939 15 to to IN 50458 939 16 animals animal NNS 50458 939 17 into into IN 50458 939 18 which which WDT 50458 939 19 it -PRON- PRP 50458 939 20 is be VBZ 50458 939 21 injected inject VBN 50458 939 22 . . . 50458 940 1 [ [ -LRB- 50458 940 2 121 121 CD 50458 940 3 ] ] -RRB- 50458 940 4 [ [ -LRB- 50458 940 5 121 121 CD 50458 940 6 ] ] -RRB- 50458 940 7 _ _ NNP 50458 940 8 Compt Compt NNP 50458 940 9 . . . 50458 941 1 rend rend VB 50458 941 2 . . . 50458 942 1 Soc Soc NNP 50458 942 2 . . . 50458 943 1 Biol Biol NNP 50458 943 2 . . . 50458 943 3 _ _ NNP 50458 943 4 , , , 50458 943 5 1893 1893 CD 50458 943 6 , , , 50458 943 7 p. p. NN 50458 943 8 294 294 CD 50458 943 9 ; ; : 50458 943 10 _ _ NNP 50458 943 11 Ibid Ibid NNP 50458 943 12 . . . 50458 943 13 _ _ NNP 50458 943 14 , , , 50458 943 15 1894 1894 CD 50458 943 16 , , , 50458 943 17 p. p. NN 50458 943 18 878 878 CD 50458 943 19 . . . 50458 944 1 Experiment experiment NN 50458 944 2 has have VBZ 50458 944 3 shown show VBN 50458 944 4 that that IN 50458 944 5 animals animal NNS 50458 944 6 that that WDT 50458 944 7 have have VBP 50458 944 8 been be VBN 50458 944 9 cured cure VBN 50458 944 10 of of IN 50458 944 11 tetanus tetanus NN 50458 944 12 possess possess VBP 50458 944 13 no no DT 50458 944 14 immunity immunity NN 50458 944 15 whatever whatever WDT 50458 944 16 against against IN 50458 944 17 tetanus tetanus NN 50458 944 18 ; ; : 50458 944 19 nevertheless nevertheless RB 50458 944 20 Behring Behring NNP 50458 944 21 and and CC 50458 944 22 Kitasato[122 Kitasato[122 NNP 50458 944 23 ] ] -RRB- 50458 944 24 first first RB 50458 944 25 , , , 50458 944 26 and and CC 50458 944 27 Wassermann Wassermann NNP 50458 944 28 and and CC 50458 944 29 Kitasato Kitasato NNP 50458 944 30 later later RB 50458 944 31 on on RB 50458 944 32 , , , 50458 944 33 succeeded succeed VBN 50458 944 34 in in IN 50458 944 35 preparing prepare VBG 50458 944 36 a a DT 50458 944 37 _ _ NNP 50458 944 38 tetanus tetanus NN 50458 944 39 antitoxin antitoxin NN 50458 944 40 _ _ NNP 50458 944 41 . . . 50458 945 1 To to TO 50458 945 2 obtain obtain VB 50458 945 3 this this DT 50458 945 4 , , , 50458 945 5 the the DT 50458 945 6 immunization immunization NN 50458 945 7 of of IN 50458 945 8 the the DT 50458 945 9 animal animal NN 50458 945 10 , , , 50458 945 11 horse horse NN 50458 945 12 or or CC 50458 945 13 cow cow NN 50458 945 14 , , , 50458 945 15 is be VBZ 50458 945 16 effected effect VBN 50458 945 17 by by IN 50458 945 18 injecting inject VBG 50458 945 19 increasing increase VBG 50458 945 20 quantities quantity NNS 50458 945 21 of of IN 50458 945 22 the the DT 50458 945 23 toxin toxin NN 50458 945 24 , , , 50458 945 25 more more RBR 50458 945 26 or or CC 50458 945 27 less less RBR 50458 945 28 attenuated attenuate VBN 50458 945 29 by by IN 50458 945 30 mixing mix VBG 50458 945 31 it -PRON- PRP 50458 945 32 with with IN 50458 945 33 Gramm Gramm NNP 50458 945 34 's 's POS 50458 945 35 iodine iodine NN 50458 945 36 solution solution NN 50458 945 37 ; ; : 50458 945 38 the the DT 50458 945 39 immunization immunization NN 50458 945 40 is be VBZ 50458 945 41 easily easily RB 50458 945 42 and and CC 50458 945 43 rapidly rapidly RB 50458 945 44 accomplished accomplish VBN 50458 945 45 by by IN 50458 945 46 the the DT 50458 945 47 process process NN 50458 945 48 devised devise VBN 50458 945 49 by by IN 50458 945 50 Roux Roux NNP 50458 945 51 and and CC 50458 945 52 Vaillard Vaillard NNP 50458 945 53 . . . 50458 946 1 [ [ -LRB- 50458 946 2 123 123 CD 50458 946 3 ] ] -RRB- 50458 946 4 [ [ -LRB- 50458 946 5 122 122 CD 50458 946 6 ] ] -RRB- 50458 946 7 _ _ NNP 50458 946 8 Deutsch Deutsch NNP 50458 946 9 . . . 50458 947 1 Med Med NNP 50458 947 2 . . . 50458 948 1 Wochenschr Wochenschr NNP 50458 948 2 . . . 50458 948 3 _ _ NNP 50458 948 4 , , , 50458 948 5 1890 1890 CD 50458 948 6 . . . 50458 949 1 [ [ -LRB- 50458 949 2 123 123 CD 50458 949 3 ] ] -RRB- 50458 949 4 _ _ NNP 50458 949 5 Annal Annal NNP 50458 949 6 . . . 50458 950 1 Instit Instit NNP 50458 950 2 . . . 50458 951 1 Pasteur Pasteur NNP 50458 951 2 _ _ NNP 50458 951 3 , , , 50458 951 4 VII VII NNP 50458 951 5 , , , 50458 951 6 p. p. NN 50458 951 7 64 64 CD 50458 951 8 . . . 50458 952 1 The the DT 50458 952 2 immunized immunized JJ 50458 952 3 animals animal NNS 50458 952 4 yield yield VBP 50458 952 5 a a DT 50458 952 6 serum serum NN 50458 952 7 which which WDT 50458 952 8 , , , 50458 952 9 mixed mix VBN 50458 952 10 with with IN 50458 952 11 tetanus tetanus NN 50458 952 12 cultures culture NNS 50458 952 13 , , , 50458 952 14 renders render VBZ 50458 952 15 these these DT 50458 952 16 innocuous innocuous JJ 50458 952 17 , , , 50458 952 18 and and CC 50458 952 19 which which WDT 50458 952 20 enjoys enjoy VBZ 50458 952 21 an an DT 50458 952 22 antitoxic antitoxic JJ 50458 952 23 power power NN 50458 952 24 that that WDT 50458 952 25 borders border VBZ 50458 952 26 on on IN 50458 952 27 the the DT 50458 952 28 marvelous marvelous JJ 50458 952 29 . . . 50458 953 1 [ [ -LRB- 50458 953 2 124 124 CD 50458 953 3 ] ] -RRB- 50458 953 4 A a DT 50458 953 5 quintillionth quintillionth NN 50458 953 6 of of IN 50458 953 7 a a DT 50458 953 8 cubic cubic JJ 50458 953 9 centimeter centimeter NN 50458 953 10 of of IN 50458 953 11 the the DT 50458 953 12 serum serum NN 50458 953 13 per per IN 50458 953 14 gramme gramme NNP 50458 953 15 weight weight NN 50458 953 16 of of IN 50458 953 17 a a DT 50458 953 18 live live JJ 50458 953 19 mouse mouse NN 50458 953 20 suffices suffice NNS 50458 953 21 to to TO 50458 953 22 protect protect VB 50458 953 23 the the DT 50458 953 24 animal animal NN 50458 953 25 from from IN 50458 953 26 an an DT 50458 953 27 otherwise otherwise RB 50458 953 28 fatal fatal JJ 50458 953 29 quantity quantity NN 50458 953 30 of of IN 50458 953 31 tetanus tetanus NN 50458 953 32 toxin toxin NN 50458 953 33 . . . 50458 954 1 [ [ -LRB- 50458 954 2 125 125 CD 50458 954 3 ] ] -RRB- 50458 954 4 [ [ -LRB- 50458 954 5 124 124 CD 50458 954 6 ] ] -RRB- 50458 954 7 NOCARD NOCARD NNP 50458 954 8 : : : 50458 954 9 _ _ NNP 50458 954 10 Bull Bull NNP 50458 954 11 . . . 50458 955 1 de de NNP 50458 955 2 l'Acad l'Acad NNP 50458 955 3 . . . 50458 956 1 de de NNP 50458 956 2 Médecine Médecine NNP 50458 956 3 _ _ NNP 50458 956 4 , , , 50458 956 5 Oct. October NNP 50458 956 6 22 22 CD 50458 956 7 , , , 50458 956 8 1895 1895 CD 50458 956 9 . . . 50458 957 1 [ [ -LRB- 50458 957 2 125 125 CD 50458 957 3 ] ] -RRB- 50458 957 4 NAILLARD NAILLARD NNP 50458 957 5 : : : 50458 957 6 _ _ NNP 50458 957 7 Compt Compt NNP 50458 957 8 . . . 50458 958 1 rend rend VB 50458 958 2 . . . 50458 959 1 de de NNP 50458 959 2 l'Acad l'Acad NNP 50458 959 3 . . . 50458 960 1 de de NNP 50458 960 2 Sciences Sciences NNP 50458 960 3 _ _ NNP 50458 960 4 , , , 50458 960 5 CXX CXX NNP 50458 960 6 , , , 50458 960 7 p. p. NN 50458 960 8 1181 1181 CD 50458 960 9 . . . 50458 961 1 This this DT 50458 961 2 serum serum NN 50458 961 3 is be VBZ 50458 961 4 nevertheless nevertheless RB 50458 961 5 powerless powerless JJ 50458 961 6 to to TO 50458 961 7 preserve preserve VB 50458 961 8 man man NN 50458 961 9 in in IN 50458 961 10 cases case NNS 50458 961 11 of of IN 50458 961 12 acute acute JJ 50458 961 13 tetanus tetanus NN 50458 961 14 ; ; : 50458 961 15 it -PRON- PRP 50458 961 16 confers confer VBZ 50458 961 17 an an DT 50458 961 18 immediate immediate NN 50458 961 19 , , , 50458 961 20 but but CC 50458 961 21 only only RB 50458 961 22 transitory transitory NN 50458 961 23 , , , 50458 961 24 immunity immunity NN 50458 961 25 . . . 50458 962 1 As as IN 50458 962 2 to to IN 50458 962 3 its -PRON- PRP$ 50458 962 4 mode mode NN 50458 962 5 of of IN 50458 962 6 action action NN 50458 962 7 , , , 50458 962 8 it -PRON- PRP 50458 962 9 appears appear VBZ 50458 962 10 to to TO 50458 962 11 cause cause VB 50458 962 12 a a DT 50458 962 13 permanent permanent JJ 50458 962 14 condition condition NN 50458 962 15 of of IN 50458 962 16 excitation excitation NN 50458 962 17 or or CC 50458 962 18 of of IN 50458 962 19 nutritive nutritive JJ 50458 962 20 reaction reaction NN 50458 962 21 of of IN 50458 962 22 the the DT 50458 962 23 cells cell NNS 50458 962 24 , , , 50458 962 25 which which WDT 50458 962 26 makes make VBZ 50458 962 27 these these DT 50458 962 28 resistant resistant JJ 50458 962 29 to to IN 50458 962 30 the the DT 50458 962 31 poison poison NN 50458 962 32 . . . 50458 963 1 As as IN 50458 963 2 in in IN 50458 963 3 the the DT 50458 963 4 case case NN 50458 963 5 of of IN 50458 963 6 the the DT 50458 963 7 other other JJ 50458 963 8 toxins toxin NNS 50458 963 9 , , , 50458 963 10 the the DT 50458 963 11 quantity quantity NN 50458 963 12 of of IN 50458 963 13 antitoxin antitoxin NN 50458 963 14 necessary necessary JJ 50458 963 15 to to TO 50458 963 16 protect protect VB 50458 963 17 an an DT 50458 963 18 organism organism NN 50458 963 19 is be VBZ 50458 963 20 so so RB 50458 963 21 much much RB 50458 963 22 greater great JJR 50458 963 23 the the DT 50458 963 24 later later RB 50458 963 25 the the DT 50458 963 26 treatment treatment NN 50458 963 27 is be VBZ 50458 963 28 applied apply VBN 50458 963 29 . . . 50458 964 1 = = NFP 50458 964 2 Mallein Mallein NNP 50458 964 3 ( ( -LRB- 50458 964 4 Toxin Toxin NNP 50458 964 5 of of IN 50458 964 6 Glanders).=--Among Glanders).=--Among NNP 50458 964 7 the the DT 50458 964 8 soluble soluble JJ 50458 964 9 products product NNS 50458 964 10 secreted secrete VBN 50458 964 11 in in IN 50458 964 12 the the DT 50458 964 13 culture culture NN 50458 964 14 media medium NNS 50458 964 15 by by IN 50458 964 16 the the DT 50458 964 17 glanders glander NNS 50458 964 18 bacilli bacilli NNP 50458 964 19 , , , 50458 964 20 there there EX 50458 964 21 are be VBP 50458 964 22 found find VBN 50458 964 23 true true JJ 50458 964 24 toxins toxin NNS 50458 964 25 to to TO 50458 964 26 which which WDT 50458 964 27 are be VBP 50458 964 28 ascribed ascribe VBN 50458 964 29 certain certain JJ 50458 964 30 symptoms symptom NNS 50458 964 31 of of IN 50458 964 32 glanders glander NNS 50458 964 33 infection infection NN 50458 964 34 . . . 50458 965 1 These these DT 50458 965 2 toxins toxin NNS 50458 965 3 have have VBP 50458 965 4 been be VBN 50458 965 5 isolated isolate VBN 50458 965 6 and and CC 50458 965 7 designated designate VBN 50458 965 8 by by IN 50458 965 9 the the DT 50458 965 10 name name NN 50458 965 11 _ _ NNP 50458 965 12 mallein mallein NNP 50458 965 13 _ _ NNP 50458 965 14 . . . 50458 966 1 First first RB 50458 966 2 prepared prepare VBN 50458 966 3 by by IN 50458 966 4 Helman Helman NNP 50458 966 5 and and CC 50458 966 6 Kalmino Kalmino NNP 50458 966 7 , , , 50458 966 8 mallein mallein NNP 50458 966 9 was be VBD 50458 966 10 later later RB 50458 966 11 on on RB 50458 966 12 specially specially RB 50458 966 13 studied study VBN 50458 966 14 by by IN 50458 966 15 Roux Roux NNP 50458 966 16 and and CC 50458 966 17 Nocard Nocard NNP 50458 966 18 , , , 50458 966 19 and and CC 50458 966 20 , , , 50458 966 21 in in IN 50458 966 22 consequence consequence NN 50458 966 23 of of IN 50458 966 24 the the DT 50458 966 25 researches research NNS 50458 966 26 of of IN 50458 966 27 the the DT 50458 966 28 last last RB 50458 966 29 - - HYPH 50458 966 30 mentioned mention VBN 50458 966 31 scientist scientist NN 50458 966 32 , , , 50458 966 33 it -PRON- PRP 50458 966 34 has have VBZ 50458 966 35 acquired acquire VBN 50458 966 36 great great JJ 50458 966 37 importance importance NN 50458 966 38 . . . 50458 967 1 [ [ -LRB- 50458 967 2 126 126 CD 50458 967 3 ] ] -RRB- 50458 967 4 It -PRON- PRP 50458 967 5 is be VBZ 50458 967 6 obtained obtain VBN 50458 967 7 by by IN 50458 967 8 sterilizing sterilize VBG 50458 967 9 at at IN 50458 967 10 110 110 CD 50458 967 11 ° ° NNS 50458 967 12 C. C. NNP 50458 967 13 cultures culture NNS 50458 967 14 of of IN 50458 967 15 the the DT 50458 967 16 glanders glander NNS 50458 967 17 bacillus bacillus NN 50458 967 18 made make VBN 50458 967 19 with with IN 50458 967 20 mutton mutton NN 50458 967 21 bouillon bouillon NN 50458 967 22 with with IN 50458 967 23 the the DT 50458 967 24 addition addition NN 50458 967 25 of of IN 50458 967 26 salt salt NN 50458 967 27 , , , 50458 967 28 glycerin glycerin NNP 50458 967 29 , , , 50458 967 30 and and CC 50458 967 31 peptones peptone NNS 50458 967 32 . . . 50458 968 1 To to TO 50458 968 2 isolate isolate VB 50458 968 3 the the DT 50458 968 4 toxin toxin NN 50458 968 5 the the DT 50458 968 6 culture culture NN 50458 968 7 bouillon bouillon NN 50458 968 8 is be VBZ 50458 968 9 first first RB 50458 968 10 sterilized sterilize VBN 50458 968 11 by by IN 50458 968 12 heating heat VBG 50458 968 13 for for IN 50458 968 14 half half PDT 50458 968 15 an an DT 50458 968 16 hour hour NN 50458 968 17 in in IN 50458 968 18 an an DT 50458 968 19 autoclave autoclave NN 50458 968 20 at at IN 50458 968 21 100 100 CD 50458 968 22 ° ° NNS 50458 968 23 C. C. NNP 50458 968 24 It -PRON- PRP 50458 968 25 is be VBZ 50458 968 26 then then RB 50458 968 27 filtered filter VBN 50458 968 28 , , , 50458 968 29 concentrated concentrate VBD 50458 968 30 to to IN 50458 968 31 one one CD 50458 968 32 - - HYPH 50458 968 33 tenth tenth NN 50458 968 34 its -PRON- PRP$ 50458 968 35 volume volume NN 50458 968 36 on on IN 50458 968 37 a a DT 50458 968 38 water water NN 50458 968 39 - - HYPH 50458 968 40 bath bath NN 50458 968 41 , , , 50458 968 42 and and CC 50458 968 43 filtered filter VBD 50458 968 44 through through IN 50458 968 45 a a DT 50458 968 46 Chardin Chardin NNP 50458 968 47 filter filter NN 50458 968 48 . . . 50458 969 1 The the DT 50458 969 2 mallein mallein NN 50458 969 3 is be VBZ 50458 969 4 thus thus RB 50458 969 5 obtained obtain VBN 50458 969 6 in in IN 50458 969 7 the the DT 50458 969 8 form form NN 50458 969 9 of of IN 50458 969 10 a a DT 50458 969 11 brown brown JJ 50458 969 12 syrupy syrupy NN 50458 969 13 liquid liquid NN 50458 969 14 containing contain VBG 50458 969 15 half half PDT 50458 969 16 its -PRON- PRP$ 50458 969 17 weight weight NN 50458 969 18 of of IN 50458 969 19 glycerin glycerin NNP 50458 969 20 . . . 50458 970 1 [ [ -LRB- 50458 970 2 126 126 CD 50458 970 3 ] ] -RRB- 50458 970 4 NOCARD NOCARD NNP 50458 970 5 : : : 50458 970 6 _ _ NNP 50458 970 7 Les Les NNP 50458 970 8 Maladies Maladies NNP 50458 970 9 microbiennes microbienne NNS 50458 970 10 des des NNP 50458 970 11 animaux animaux NNP 50458 970 12 _ _ NNP 50458 970 13 , , , 50458 970 14 Paris Paris NNP 50458 970 15 . . . 50458 971 1 This this DT 50458 971 2 solution solution NN 50458 971 3 keeps keep VBZ 50458 971 4 well well RB 50458 971 5 when when WRB 50458 971 6 kept keep VBN 50458 971 7 from from IN 50458 971 8 air air NN 50458 971 9 , , , 50458 971 10 light light NN 50458 971 11 , , , 50458 971 12 and and CC 50458 971 13 heat heat NN 50458 971 14 . . . 50458 972 1 In in IN 50458 972 2 practice practice NN 50458 972 3 it -PRON- PRP 50458 972 4 is be VBZ 50458 972 5 employed employ VBN 50458 972 6 in in IN 50458 972 7 10-per 10-per CD 50458 972 8 cent cent NN 50458 972 9 . . . 50458 973 1 solution solution NN 50458 973 2 in in IN 50458 973 3 phenolated phenolate VBN 50458 973 4 water water NN 50458 973 5 ( ( -LRB- 50458 973 6 5:1000 5:1000 CD 50458 973 7 ) ) -RRB- 50458 973 8 . . . 50458 974 1 The the DT 50458 974 2 mallein mallein NN 50458 974 3 may may MD 50458 974 4 be be VB 50458 974 5 precipitated precipitate VBN 50458 974 6 from from IN 50458 974 7 the the DT 50458 974 8 crude crude JJ 50458 974 9 solution solution NN 50458 974 10 by by IN 50458 974 11 the the DT 50458 974 12 addition addition NN 50458 974 13 of of IN 50458 974 14 alcohol alcohol NN 50458 974 15 , , , 50458 974 16 as as IN 50458 974 17 recommended recommend VBN 50458 974 18 by by IN 50458 974 19 Foth Foth NNP 50458 974 20 . . . 50458 975 1 Foth Foth NNP 50458 975 2 's 's POS 50458 975 3 mallein mallein NN 50458 975 4 occurs occur VBZ 50458 975 5 as as IN 50458 975 6 a a DT 50458 975 7 white white JJ 50458 975 8 , , , 50458 975 9 light light JJ 50458 975 10 powder powder NN 50458 975 11 , , , 50458 975 12 very very RB 50458 975 13 easily easily RB 50458 975 14 soluble soluble JJ 50458 975 15 in in IN 50458 975 16 water water NN 50458 975 17 . . . 50458 976 1 Mallein Mallein NNP 50458 976 2 enjoys enjoy VBZ 50458 976 3 a a DT 50458 976 4 very very RB 50458 976 5 important important JJ 50458 976 6 rôle rôle NN 50458 976 7 in in IN 50458 976 8 veterinary veterinary JJ 50458 976 9 therapeutics therapeutic NNS 50458 976 10 , , , 50458 976 11 a a DT 50458 976 12 rôle rôle NN 50458 976 13 analogous analogous JJ 50458 976 14 to to IN 50458 976 15 that that DT 50458 976 16 of of IN 50458 976 17 tuberculin tuberculin NN 50458 976 18 , , , 50458 976 19 permitting permit VBG 50458 976 20 the the DT 50458 976 21 diagnosis diagnosis NN 50458 976 22 of of IN 50458 976 23 incipient incipient JJ 50458 976 24 glanders glander NNS 50458 976 25 . . . 50458 977 1 [ [ -LRB- 50458 977 2 127 127 CD 50458 977 3 ] ] -RRB- 50458 977 4 [ [ -LRB- 50458 977 5 127 127 CD 50458 977 6 ] ] -RRB- 50458 977 7 STRAUSS STRAUSS NNP 50458 977 8 : : : 50458 977 9 _ _ NNP 50458 977 10 Arch Arch NNP 50458 977 11 . . . 50458 978 1 de de NNP 50458 978 2 Médic Médic NNP 50458 978 3 . . . 50458 979 1 expériment expériment NNP 50458 979 2 _ _ NNP 50458 979 3 , , , 50458 979 4 1886 1886 CD 50458 979 5 . . . 50458 980 1 Experience experience NN 50458 980 2 has have VBZ 50458 980 3 shown show VBN 50458 980 4 that that IN 50458 980 5 in in IN 50458 980 6 animals animal NNS 50458 980 7 already already RB 50458 980 8 attacked attack VBN 50458 980 9 by by IN 50458 980 10 glanders glander NNS 50458 980 11 , , , 50458 980 12 even even RB 50458 980 13 if if IN 50458 980 14 ever ever RB 50458 980 15 so so RB 50458 980 16 slightly slightly RB 50458 980 17 , , , 50458 980 18 the the DT 50458 980 19 thermic thermic NN 50458 980 20 reaction reaction NN 50458 980 21 never never RB 50458 980 22 fails fail VBZ 50458 980 23 when when WRB 50458 980 24 0.25 0.25 CD 50458 980 25 Cc Cc NNP 50458 980 26 . . . 50458 981 1 of of IN 50458 981 2 the the DT 50458 981 3 mallein mallein NNP 50458 981 4 solution solution NN 50458 981 5 is be VBZ 50458 981 6 injected inject VBN 50458 981 7 . . . 50458 982 1 In in IN 50458 982 2 healthy healthy JJ 50458 982 3 animals animal NNS 50458 982 4 , , , 50458 982 5 however however RB 50458 982 6 , , , 50458 982 7 the the DT 50458 982 8 injection injection NN 50458 982 9 of of IN 50458 982 10 mallein mallein NNP 50458 982 11 , , , 50458 982 12 even even RB 50458 982 13 in in IN 50458 982 14 much much RB 50458 982 15 larger large JJR 50458 982 16 quantities quantity NNS 50458 982 17 , , , 50458 982 18 causes cause VBZ 50458 982 19 no no DT 50458 982 20 apparent apparent JJ 50458 982 21 effect effect NN 50458 982 22 . . . 50458 983 1 In in IN 50458 983 2 animals animal NNS 50458 983 3 attacked attack VBN 50458 983 4 by by IN 50458 983 5 glanders glander NNS 50458 983 6 the the DT 50458 983 7 reaction reaction NN 50458 983 8 attains attain VBZ 50458 983 9 its -PRON- PRP$ 50458 983 10 maximum maximum NN 50458 983 11 in in IN 50458 983 12 twelve twelve CD 50458 983 13 hours hour NNS 50458 983 14 , , , 50458 983 15 and and CC 50458 983 16 several several JJ 50458 983 17 days day NNS 50458 983 18 are be VBP 50458 983 19 required require VBN 50458 983 20 for for IN 50458 983 21 the the DT 50458 983 22 temperature temperature NN 50458 983 23 to to TO 50458 983 24 return return VB 50458 983 25 to to IN 50458 983 26 normal normal JJ 50458 983 27 . . . 50458 984 1 [ [ -LRB- 50458 984 2 128 128 CD 50458 984 3 ] ] -RRB- 50458 984 4 [ [ -LRB- 50458 984 5 128 128 CD 50458 984 6 ] ] -RRB- 50458 984 7 CADIOT CADIOT NNP 50458 984 8 and and CC 50458 984 9 ROGER ROGER NNP 50458 984 10 : : : 50458 984 11 _ _ NNP 50458 984 12 Compt Compt NNP 50458 984 13 . . . 50458 985 1 rend rend VB 50458 985 2 . . . 50458 986 1 Soc Soc NNP 50458 986 2 . . . 50458 987 1 Biol Biol NNP 50458 987 2 . . . 50458 987 3 _ _ NNP 50458 987 4 , , , 50458 987 5 1895 1895 CD 50458 987 6 , , , 50458 987 7 p. p. NN 50458 987 8 770 770 CD 50458 987 9 ; ; : 50458 987 10 WLADIMIROW WLADIMIROW NNP 50458 987 11 : : : 50458 987 12 _ _ NNP 50458 987 13 Arch Arch NNP 50458 987 14 . . . 50458 988 1 des des NNP 50458 988 2 Sciences Sciences NNPS 50458 988 3 Biol Biol NNP 50458 988 4 . . . 50458 989 1 de de NNP 50458 989 2 St.-Pétersbourg St.-Pétersbourg NNP 50458 989 3 _ _ NNP 50458 989 4 , , , 50458 989 5 IV IV NNP 50458 989 6 , , , 50458 989 7 p. p. NN 50458 989 8 30 30 CD 50458 989 9 ; ; : 50458 989 10 BOURGES bourges NN 50458 989 11 and and CC 50458 989 12 MÉRY MÉRY NNP 50458 989 13 : : : 50458 989 14 _ _ NNP 50458 989 15 Soc Soc NNP 50458 989 16 . . . 50458 990 1 de de NNP 50458 990 2 Biol Biol NNP 50458 990 3 . . . 50458 990 4 _ _ NNP 50458 990 5 , , , 50458 990 6 Feb. February NNP 50458 990 7 5 5 CD 50458 990 8 , , , 50458 990 9 1878 1878 CD 50458 990 10 . . . 50458 991 1 According accord VBG 50458 991 2 to to IN 50458 991 3 Nocard Nocard NNP 50458 991 4 , , , 50458 991 5 mallein mallein NNP 50458 991 6 possesses possess VBZ 50458 991 7 no no DT 50458 991 8 immunizing immunize VBG 50458 991 9 properties property NNS 50458 991 10 whatever whatever WDT 50458 991 11 . . . 50458 992 1 [ [ -LRB- 50458 992 2 129 129 CD 50458 992 3 ] ] -RRB- 50458 992 4 [ [ -LRB- 50458 992 5 129 129 CD 50458 992 6 ] ] -RRB- 50458 992 7 GALTIER GALTIER NNP 50458 992 8 : : : 50458 992 9 _ _ NNP 50458 992 10 Compt Compt NNP 50458 992 11 . . . 50458 993 1 rend rend VB 50458 993 2 . . . 50458 994 1 de de NNP 50458 994 2 l'Acad l'Acad NNP 50458 994 3 . . . 50458 995 1 des des NNP 50458 995 2 Sciences Sciences NNPS 50458 995 3 _ _ NNP 50458 995 4 , , , 50458 995 5 XCII XCII NNP 50458 995 6 , , , 50458 995 7 p. p. NN 50458 995 8 303 303 CD 50458 995 9 ; ; : 50458 995 10 STRAUSS STRAUSS NNP 50458 995 11 : : : 50458 995 12 _ _ NNP 50458 995 13 Arch Arch NNP 50458 995 14 . . . 50458 996 1 de de NNP 50458 996 2 Médic Médic NNP 50458 996 3 . . . 50458 997 1 expériment expériment NNP 50458 997 2 _ _ NNP 50458 997 3 , , , 50458 997 4 I -PRON- PRP 50458 997 5 , , , 50458 997 6 p. p. NN 50458 997 7 489 489 CD 50458 997 8 . . . 50458 998 1 = = NFP 50458 998 2 Typhoid Typhoid NNP 50458 998 3 Toxin.=--This Toxin.=--This NNP 50458 998 4 is be VBZ 50458 998 5 obtained obtain VBN 50458 998 6 , , , 50458 998 7 like like IN 50458 998 8 the the DT 50458 998 9 other other JJ 50458 998 10 microbial microbial JJ 50458 998 11 toxins toxin NNS 50458 998 12 , , , 50458 998 13 from from IN 50458 998 14 a a DT 50458 998 15 culture culture NN 50458 998 16 , , , 50458 998 17 prepared prepare VBN 50458 998 18 with with IN 50458 998 19 more more JJR 50458 998 20 or or CC 50458 998 21 less less JJR 50458 998 22 difficulty difficulty NN 50458 998 23 , , , 50458 998 24 from from IN 50458 998 25 Eberth Eberth NNP 50458 998 26 's 's POS 50458 998 27 typhoid typhoid NN 50458 998 28 bacillus bacillus NN 50458 998 29 . . . 50458 999 1 This this DT 50458 999 2 toxin toxin NN 50458 999 3 , , , 50458 999 4 injected inject VBN 50458 999 5 into into IN 50458 999 6 guinea guinea NN 50458 999 7 - - HYPH 50458 999 8 pigs pig NNS 50458 999 9 , , , 50458 999 10 develops develop VBZ 50458 999 11 in in IN 50458 999 12 them -PRON- PRP 50458 999 13 typhoid typhoid JJ 50458 999 14 fever fever NN 50458 999 15 . . . 50458 1000 1 In in IN 50458 1000 2 the the DT 50458 1000 3 solution solution NN 50458 1000 4 there there EX 50458 1000 5 occurs occur VBZ 50458 1000 6 a a DT 50458 1000 7 ptomaine ptomaine NN 50458 1000 8 , , , 50458 1000 9 which which WDT 50458 1000 10 has have VBZ 50458 1000 11 been be VBN 50458 1000 12 isolated isolate VBN 50458 1000 13 by by IN 50458 1000 14 Brieger Brieger NNP 50458 1000 15 , , , 50458 1000 16 and and CC 50458 1000 17 which which WDT 50458 1000 18 gives give VBZ 50458 1000 19 rise rise NN 50458 1000 20 to to IN 50458 1000 21 almost almost RB 50458 1000 22 all all PDT 50458 1000 23 the the DT 50458 1000 24 phenomena phenomenon NNS 50458 1000 25 of of IN 50458 1000 26 typhoid typhoid NN 50458 1000 27 fever fever NN 50458 1000 28 ; ; : 50458 1000 29 this this DT 50458 1000 30 ptomaine ptomaine NN 50458 1000 31 is be VBZ 50458 1000 32 called call VBN 50458 1000 33 _ _ NNP 50458 1000 34 typhotoxin typhotoxin NN 50458 1000 35 _ _ NNP 50458 1000 36 . . . 50458 1001 1 [ [ -LRB- 50458 1001 2 130 130 CD 50458 1001 3 ] ] -RRB- 50458 1001 4 [ [ -LRB- 50458 1001 5 130 130 CD 50458 1001 6 ] ] -RRB- 50458 1001 7 BRIEGER BRIEGER NNP 50458 1001 8 : : : 50458 1001 9 _ _ NNP 50458 1001 10 Microbes Microbes NNPS 50458 1001 11 , , , 50458 1001 12 Ptomaïnes Ptomaïnes NNPS 50458 1001 13 et et NNP 50458 1001 14 Maladies malady NNS 50458 1001 15 _ _ NNP 50458 1001 16 , , , 50458 1001 17 Doin do NNP 50458 1001 18 , , , 50458 1001 19 publ publ NNS 50458 1001 20 . . . 50458 1001 21 , , , 50458 1001 22 Paris Paris NNP 50458 1001 23 , , , 50458 1001 24 1887 1887 CD 50458 1001 25 ; ; : 50458 1001 26 LUFF LUFF NNP 50458 1001 27 : : : 50458 1001 28 _ _ NNP 50458 1001 29 Brit Brit NNP 50458 1001 30 . . . 50458 1002 1 Med Med NNP 50458 1002 2 . . . 50458 1003 1 Journ Journ NNP 50458 1003 2 . . . 50458 1003 3 _ _ NNP 50458 1003 4 , , , 50458 1003 5 1889 1889 CD 50458 1003 6 . . . 50458 1004 1 The the DT 50458 1004 2 same same JJ 50458 1004 3 author author NN 50458 1004 4 , , , 50458 1004 5 in in IN 50458 1004 6 collaboration collaboration NN 50458 1004 7 with with IN 50458 1004 8 Fraenkel,[131 Fraenkel,[131 NNP 50458 1004 9 ] ] -RRB- 50458 1004 10 later later RB 50458 1004 11 on on IN 50458 1004 12 isolated isolate VBN 50458 1004 13 a a DT 50458 1004 14 toxalbumin toxalbumin NN 50458 1004 15 from from IN 50458 1004 16 the the DT 50458 1004 17 culture culture NN 50458 1004 18 bouillon bouillon NN 50458 1004 19 of of IN 50458 1004 20 the the DT 50458 1004 21 typhoid typhoid NN 50458 1004 22 bacillus bacillus NN 50458 1004 23 . . . 50458 1005 1 Sanarelli[132 sanarelli[132 NN 50458 1005 2 ] ] -RRB- 50458 1005 3 obtained obtain VBD 50458 1005 4 an an DT 50458 1005 5 active active JJ 50458 1005 6 toxin toxin NN 50458 1005 7 by by IN 50458 1005 8 macerating macerate VBG 50458 1005 9 for for IN 50458 1005 10 several several JJ 50458 1005 11 days day NNS 50458 1005 12 at at IN 50458 1005 13 60 60 CD 50458 1005 14 ° ° NNS 50458 1005 15 C. C. NNP 50458 1005 16 a a DT 50458 1005 17 month month NN 50458 1005 18 - - HYPH 50458 1005 19 old old JJ 50458 1005 20 culture culture NN 50458 1005 21 of of IN 50458 1005 22 the the DT 50458 1005 23 typhoid typhoid NN 50458 1005 24 bacillus bacillus NN 50458 1005 25 made make VBN 50458 1005 26 with with IN 50458 1005 27 a a DT 50458 1005 28 2-per 2-per CD 50458 1005 29 cent cent NN 50458 1005 30 . . . 50458 1006 1 glycerin glycerin NNP 50458 1006 2 - - HYPH 50458 1006 3 bouillon bouillon NNP 50458 1006 4 . . . 50458 1007 1 Chantemesse Chantemesse NNP 50458 1007 2 has have VBZ 50458 1007 3 also also RB 50458 1007 4 published publish VBN 50458 1007 5 a a DT 50458 1007 6 process process NN 50458 1007 7 which which WDT 50458 1007 8 yields yield VBZ 50458 1007 9 a a DT 50458 1007 10 highly highly RB 50458 1007 11 virulent virulent JJ 50458 1007 12 toxin toxin NN 50458 1007 13 . . . 50458 1008 1 [ [ -LRB- 50458 1008 2 133 133 CD 50458 1008 3 ] ] -RRB- 50458 1008 4 [ [ -LRB- 50458 1008 5 131 131 CD 50458 1008 6 ] ] -RRB- 50458 1008 7 _ _ NNP 50458 1008 8 Berlin Berlin NNP 50458 1008 9 . . . 50458 1009 1 Klin Klin NNP 50458 1009 2 . . . 50458 1010 1 Wochenschr Wochenschr NNP 50458 1010 2 . . . 50458 1010 3 _ _ NNP 50458 1010 4 , , , 50458 1010 5 1890 1890 CD 50458 1010 6 . . . 50458 1011 1 [ [ -LRB- 50458 1011 2 132 132 CD 50458 1011 3 ] ] -RRB- 50458 1011 4 _ _ NNP 50458 1011 5 Annal Annal NNP 50458 1011 6 . . . 50458 1012 1 de de NNP 50458 1012 2 l'Instit l'Instit NNP 50458 1012 3 . . . 50458 1013 1 Pasteur Pasteur NNP 50458 1013 2 _ _ NNP 50458 1013 3 , , , 50458 1013 4 VIII VIII NNP 50458 1013 5 , , , 50458 1013 6 p. p. NN 50458 1013 7 103 103 CD 50458 1013 8 . . . 50458 1014 1 [ [ -LRB- 50458 1014 2 133 133 CD 50458 1014 3 ] ] -RRB- 50458 1014 4 _ _ NNP 50458 1014 5 Compt Compt NNP 50458 1014 6 . . . 50458 1015 1 rend rend VB 50458 1015 2 . . . 50458 1016 1 Soc Soc NNP 50458 1016 2 . . . 50458 1017 1 de de NNP 50458 1017 2 Biol Biol NNP 50458 1017 3 . . . 50458 1017 4 _ _ NNP 50458 1017 5 , , , 50458 1017 6 p. p. NN 50458 1017 7 232 232 CD 50458 1017 8 , , , 50458 1017 9 Jan. January NNP 50458 1017 10 30 30 CD 50458 1017 11 , , , 50458 1017 12 1897 1897 CD 50458 1017 13 . . . 50458 1018 1 _ _ NNP 50458 1018 2 Congrès Congrès NNP 50458 1018 3 d'Hygiène d'Hygiène NNP 50458 1018 4 de de NNP 50458 1018 5 Madrid Madrid NNP 50458 1018 6 _ _ NNP 50458 1018 7 , , , 50458 1018 8 1898 1898 CD 50458 1018 9 . . . 50458 1019 1 Chantemesse chantemesse NN 50458 1019 2 and and CC 50458 1019 3 Widal[134 Widal[134 NNP 50458 1019 4 ] ] -RRB- 50458 1019 5 have have VBP 50458 1019 6 shown show VBN 50458 1019 7 that that IN 50458 1019 8 on on IN 50458 1019 9 injecting inject VBG 50458 1019 10 into into IN 50458 1019 11 an an DT 50458 1019 12 organism organism NN 50458 1019 13 increasing increase VBG 50458 1019 14 quantities quantity NNS 50458 1019 15 of of IN 50458 1019 16 the the DT 50458 1019 17 sterilized sterilize VBN 50458 1019 18 cultures culture NNS 50458 1019 19 of of IN 50458 1019 20 Eberth Eberth NNP 50458 1019 21 's 's POS 50458 1019 22 Bacillus Bacillus NNP 50458 1019 23 , , , 50458 1019 24 it -PRON- PRP 50458 1019 25 is be VBZ 50458 1019 26 possible possible JJ 50458 1019 27 to to TO 50458 1019 28 fully fully RB 50458 1019 29 immunize immunize VB 50458 1019 30 an an DT 50458 1019 31 animal animal NN 50458 1019 32 against against IN 50458 1019 33 the the DT 50458 1019 34 bacillus bacillus NN 50458 1019 35 itself -PRON- PRP 50458 1019 36 , , , 50458 1019 37 and and CC 50458 1019 38 even even RB 50458 1019 39 also also RB 50458 1019 40 against against IN 50458 1019 41 the the DT 50458 1019 42 Bacillus Bacillus NNP 50458 1019 43 coli coli NNS 50458 1019 44 communis communis NN 50458 1019 45 . . . 50458 1020 1 The the DT 50458 1020 2 operation operation NN 50458 1020 3 , , , 50458 1020 4 however however RB 50458 1020 5 , , , 50458 1020 6 is be VBZ 50458 1020 7 tedious tedious JJ 50458 1020 8 and and CC 50458 1020 9 painful painful JJ 50458 1020 10 . . . 50458 1021 1 The the DT 50458 1021 2 serum serum NN 50458 1021 3 of of IN 50458 1021 4 immunized immunized JJ 50458 1021 5 animals animal NNS 50458 1021 6 possesses possess VBZ 50458 1021 7 preventive preventive JJ 50458 1021 8 and and CC 50458 1021 9 curative curative JJ 50458 1021 10 properties property NNS 50458 1021 11 respecting respect VBG 50458 1021 12 the the DT 50458 1021 13 effects effect NNS 50458 1021 14 of of IN 50458 1021 15 typhoid typhoid NNP 50458 1021 16 bacilli bacilli NNP 50458 1021 17 . . . 50458 1022 1 [ [ -LRB- 50458 1022 2 134 134 CD 50458 1022 3 ] ] -RRB- 50458 1022 4 _ _ NNP 50458 1022 5 Annal Annal NNP 50458 1022 6 . . . 50458 1023 1 l'Instit l'Instit NNP 50458 1023 2 . . . 50458 1024 1 Pasteur Pasteur NNP 50458 1024 2 _ _ NNP 50458 1024 3 , , , 50458 1024 4 VI VI NNP 50458 1024 5 , , , 50458 1024 6 p. p. NN 50458 1024 7 755 755 CD 50458 1024 8 ; ; : 50458 1024 9 SANARELLI sanarelli NN 50458 1024 10 : : : 50458 1024 11 _ _ NNP 50458 1024 12 Ibid Ibid NNP 50458 1024 13 . . . 50458 1024 14 _ _ NNP 50458 1024 15 , , , 50458 1024 16 p. p. NN 50458 1024 17 721 721 CD 50458 1024 18 . . . 50458 1025 1 A a DT 50458 1025 2 dose dose NN 50458 1025 3 of of IN 50458 1025 4 the the DT 50458 1025 5 filtered filter VBN 50458 1025 6 culture culture NN 50458 1025 7 , , , 50458 1025 8 which which WDT 50458 1025 9 is be VBZ 50458 1025 10 fatal fatal JJ 50458 1025 11 to to IN 50458 1025 12 a a DT 50458 1025 13 guinea guinea NN 50458 1025 14 - - HYPH 50458 1025 15 pig pig NN 50458 1025 16 , , , 50458 1025 17 becomes become VBZ 50458 1025 18 innocuous innocuous JJ 50458 1025 19 when when WRB 50458 1025 20 mixed mix VBN 50458 1025 21 with with IN 50458 1025 22 0.5 0.5 CD 50458 1025 23 Cc Cc NNP 50458 1025 24 . . . 50458 1026 1 of of IN 50458 1026 2 the the DT 50458 1026 3 serum serum NN 50458 1026 4 of of IN 50458 1026 5 a a DT 50458 1026 6 vaccinated vaccinated JJ 50458 1026 7 guinea guinea NN 50458 1026 8 - - HYPH 50458 1026 9 pig pig NN 50458 1026 10 ; ; : 50458 1026 11 6 6 CD 50458 1026 12 Cc Cc NNP 50458 1026 13 . . . 50458 1027 1 of of IN 50458 1027 2 the the DT 50458 1027 3 serum serum NN 50458 1027 4 injected inject VBD 50458 1027 5 six six CD 50458 1027 6 hours hour NNS 50458 1027 7 after after IN 50458 1027 8 an an DT 50458 1027 9 injection injection NN 50458 1027 10 of of IN 50458 1027 11 the the DT 50458 1027 12 virulent virulent NN 50458 1027 13 culture culture NN 50458 1027 14 , , , 50458 1027 15 hence hence RB 50458 1027 16 when when WRB 50458 1027 17 this this DT 50458 1027 18 is be VBZ 50458 1027 19 in in IN 50458 1027 20 full full JJ 50458 1027 21 action action NN 50458 1027 22 , , , 50458 1027 23 suffice suffice VBP 50458 1027 24 to to TO 50458 1027 25 save save VB 50458 1027 26 the the DT 50458 1027 27 animal animal NN 50458 1027 28 . . . 50458 1028 1 [ [ -LRB- 50458 1028 2 135 135 CD 50458 1028 3 ] ] -RRB- 50458 1028 4 So so RB 50458 1028 5 far far RB 50458 1028 6 as as IN 50458 1028 7 the the DT 50458 1028 8 human human NN 50458 1028 9 being being NN 50458 1028 10 is be VBZ 50458 1028 11 concerned concern VBN 50458 1028 12 , , , 50458 1028 13 the the DT 50458 1028 14 results result NNS 50458 1028 15 obtained obtain VBD 50458 1028 16 have have VBP 50458 1028 17 not not RB 50458 1028 18 been be VBN 50458 1028 19 sufficiently sufficiently RB 50458 1028 20 satisfactory satisfactory JJ 50458 1028 21 . . . 50458 1029 1 [ [ -LRB- 50458 1029 2 135 135 CD 50458 1029 3 ] ] -RRB- 50458 1029 4 FUNCK FUNCK NNP 50458 1029 5 : : : 50458 1029 6 _ _ NNP 50458 1029 7 La La NNP 50458 1029 8 Sérothérapie Sérothérapie NNP 50458 1029 9 de de NNP 50458 1029 10 la la NNP 50458 1029 11 Fièvre Fièvre NNP 50458 1029 12 Typhoïde Typhoïde NNP 50458 1029 13 _ _ NNP 50458 1029 14 , , , 50458 1029 15 I -PRON- PRP 50458 1029 16 , , , 50458 1029 17 Brussels Brussels NNP 50458 1029 18 , , , 50458 1029 19 1896 1896 CD 50458 1029 20 . . . 50458 1030 1 The the DT 50458 1030 2 culture culture NN 50458 1030 3 bouillon bouillon NN 50458 1030 4 of of IN 50458 1030 5 the the DT 50458 1030 6 Bacillus Bacillus NNP 50458 1030 7 coli coli NNS 50458 1030 8 communis communis NN 50458 1030 9 , , , 50458 1030 10 which which WDT 50458 1030 11 is be VBZ 50458 1030 12 closely closely RB 50458 1030 13 allied ally VBN 50458 1030 14 to to IN 50458 1030 15 Eberth Eberth NNP 50458 1030 16 's 's POS 50458 1030 17 bacillus bacillus NN 50458 1030 18 , , , 50458 1030 19 also also RB 50458 1030 20 contains contain VBZ 50458 1030 21 soluble soluble JJ 50458 1030 22 toxic toxic JJ 50458 1030 23 substances substance NNS 50458 1030 24 which which WDT 50458 1030 25 have have VBP 50458 1030 26 been be VBN 50458 1030 27 named name VBN 50458 1030 28 coli coli NNS 50458 1030 29 - - HYPH 50458 1030 30 bacillus bacillus NN 50458 1030 31 toxin toxin NN 50458 1030 32 . . . 50458 1031 1 This this DT 50458 1031 2 substance substance NN 50458 1031 3 , , , 50458 1031 4 which which WDT 50458 1031 5 is be VBZ 50458 1031 6 produced produce VBN 50458 1031 7 only only RB 50458 1031 8 in in IN 50458 1031 9 small small JJ 50458 1031 10 quantity quantity NN 50458 1031 11 by by IN 50458 1031 12 the the DT 50458 1031 13 microbe microbe NN 50458 1031 14 , , , 50458 1031 15 is be VBZ 50458 1031 16 fatal fatal JJ 50458 1031 17 only only RB 50458 1031 18 in in IN 50458 1031 19 very very RB 50458 1031 20 large large JJ 50458 1031 21 doses dose NNS 50458 1031 22 . . . 50458 1032 1 = = NFP 50458 1032 2 Cholera Cholera NNP 50458 1032 3 Toxin.=--Very toxin.=--very NN 50458 1032 4 little little JJ 50458 1032 5 is be VBZ 50458 1032 6 known know VBN 50458 1032 7 regarding regard VBG 50458 1032 8 the the DT 50458 1032 9 toxic toxic JJ 50458 1032 10 products product NNS 50458 1032 11 of of IN 50458 1032 12 the the DT 50458 1032 13 spirillium spirillium NN 50458 1032 14 choleræ choleræ JJ 50458 1032 15 ; ; : 50458 1032 16 nevertheless nevertheless RB 50458 1032 17 , , , 50458 1032 18 the the DT 50458 1032 19 fact fact NN 50458 1032 20 that that IN 50458 1032 21 typical typical JJ 50458 1032 22 cholera cholera NN 50458 1032 23 exhibits exhibit VBZ 50458 1032 24 every every DT 50458 1032 25 symptom symptom NN 50458 1032 26 of of IN 50458 1032 27 the the DT 50458 1032 28 action action NN 50458 1032 29 of of IN 50458 1032 30 a a DT 50458 1032 31 toxic toxic JJ 50458 1032 32 agent agent NN 50458 1032 33 demonstrates demonstrate VBZ 50458 1032 34 quite quite RB 50458 1032 35 clearly clearly RB 50458 1032 36 the the DT 50458 1032 37 elaboration elaboration NN 50458 1032 38 of of IN 50458 1032 39 some some DT 50458 1032 40 toxic toxic JJ 50458 1032 41 substance substance NN 50458 1032 42 within within IN 50458 1032 43 the the DT 50458 1032 44 cultures culture NNS 50458 1032 45 of of IN 50458 1032 46 this this DT 50458 1032 47 microbe microbe NN 50458 1032 48 . . . 50458 1033 1 Villiers[136 Villiers[136 NNP 50458 1033 2 ] ] -RRB- 50458 1033 3 found find VBN 50458 1033 4 in in IN 50458 1033 5 it -PRON- PRP 50458 1033 6 a a DT 50458 1033 7 liquid liquid JJ 50458 1033 8 ptomaine ptomaine NN 50458 1033 9 ; ; : 50458 1033 10 Klebs[137 Klebs[137 NNP 50458 1033 11 ] ] -RRB- 50458 1033 12 found find VBD 50458 1033 13 another another DT 50458 1033 14 and and CC 50458 1033 15 crystallizable crystallizable JJ 50458 1033 16 ptomaine ptomaine NN 50458 1033 17 ; ; : 50458 1033 18 while while IN 50458 1033 19 Pitai Pitai NNP 50458 1033 20 discovered discover VBD 50458 1033 21 in in IN 50458 1033 22 it -PRON- PRP 50458 1033 23 a a DT 50458 1033 24 toxin toxin NN 50458 1033 25 unalterable unalterable JJ 50458 1033 26 by by IN 50458 1033 27 heat heat NN 50458 1033 28 , , , 50458 1033 29 and and CC 50458 1033 30 which which WDT 50458 1033 31 he -PRON- PRP 50458 1033 32 considered consider VBD 50458 1033 33 as as IN 50458 1033 34 a a DT 50458 1033 35 toxopeptone toxopeptone NN 50458 1033 36 . . . 50458 1034 1 According accord VBG 50458 1034 2 to to IN 50458 1034 3 Gamaleia[138 gamaleia[138 CD 50458 1034 4 ] ] -RRB- 50458 1034 5 there there EX 50458 1034 6 is be VBZ 50458 1034 7 present present JJ 50458 1034 8 a a DT 50458 1034 9 true true JJ 50458 1034 10 toxin toxin NN 50458 1034 11 , , , 50458 1034 12 alterable alterable JJ 50458 1034 13 by by IN 50458 1034 14 heat heat NN 50458 1034 15 , , , 50458 1034 16 and and CC 50458 1034 17 the the DT 50458 1034 18 reactions reaction NNS 50458 1034 19 of of IN 50458 1034 20 which which WDT 50458 1034 21 entitle entitle VBP 50458 1034 22 it -PRON- PRP 50458 1034 23 to to TO 50458 1034 24 be be VB 50458 1034 25 considered consider VBN 50458 1034 26 as as IN 50458 1034 27 a a DT 50458 1034 28 nucleo nucleo NN 50458 1034 29 - - HYPH 50458 1034 30 albumin albumin NN 50458 1034 31 ; ; : 50458 1034 32 he -PRON- PRP 50458 1034 33 has have VBZ 50458 1034 34 also also RB 50458 1034 35 found find VBN 50458 1034 36 in in IN 50458 1034 37 it -PRON- PRP 50458 1034 38 a a DT 50458 1034 39 toxic toxic JJ 50458 1034 40 nuclein nuclein NN 50458 1034 41 . . . 50458 1035 1 [ [ -LRB- 50458 1035 2 136 136 CD 50458 1035 3 ] ] -RRB- 50458 1035 4 _ _ NNP 50458 1035 5 Compt Compt NNP 50458 1035 6 . . . 50458 1036 1 rend rend VB 50458 1036 2 . . . 50458 1037 1 de de NNP 50458 1037 2 l'Acad l'Acad NNP 50458 1037 3 . . . 50458 1038 1 des des NNP 50458 1038 2 Sciences Sciences NNPS 50458 1038 3 _ _ NNP 50458 1038 4 , , , 50458 1038 5 Jan. January NNP 50458 1038 6 12 12 CD 50458 1038 7 , , , 50458 1038 8 1885 1885 CD 50458 1038 9 . . . 50458 1039 1 [ [ -LRB- 50458 1039 2 137 137 CD 50458 1039 3 ] ] -RRB- 50458 1039 4 KLEBS KLEBS NNP 50458 1039 5 : : : 50458 1039 6 _ _ NNP 50458 1039 7 Allgem Allgem NNP 50458 1039 8 . . . 50458 1040 1 Wien Wien NNP 50458 1040 2 . . . 50458 1041 1 Med Med NNP 50458 1041 2 . . . 50458 1042 1 Zeit Zeit NNP 50458 1042 2 . . . 50458 1042 3 _ _ NNP 50458 1042 4 , , , 50458 1042 5 1887 1887 CD 50458 1042 6 . . . 50458 1043 1 [ [ -LRB- 50458 1043 2 138 138 CD 50458 1043 3 ] ] -RRB- 50458 1043 4 _ _ NNP 50458 1043 5 Arch Arch NNP 50458 1043 6 . . . 50458 1044 1 de de NNP 50458 1044 2 Méd Méd NNP 50458 1044 3 . . . 50458 1045 1 Expérim Expérim NNP 50458 1045 2 . . . 50458 1045 3 _ _ NNP 50458 1045 4 , , , 50458 1045 5 IV IV NNP 50458 1045 6 , , , 50458 1045 7 p. p. NN 50458 1045 8 173 173 CD 50458 1045 9 . . . 50458 1046 1 These these DT 50458 1046 2 toxic toxic JJ 50458 1046 3 substances substance NNS 50458 1046 4 are be VBP 50458 1046 5 found find VBN 50458 1046 6 , , , 50458 1046 7 according accord VBG 50458 1046 8 to to IN 50458 1046 9 Gamaleia Gamaleia NNP 50458 1046 10 , , , 50458 1046 11 Pfeiffer Pfeiffer NNP 50458 1046 12 , , , 50458 1046 13 and and CC 50458 1046 14 Sanarelli,[139 Sanarelli,[139 NNP 50458 1046 15 ] ] -RRB- 50458 1046 16 confined confine VBN 50458 1046 17 during during IN 50458 1046 18 the the DT 50458 1046 19 life life NN 50458 1046 20 of of IN 50458 1046 21 the the DT 50458 1046 22 microbe microbe NN 50458 1046 23 within within IN 50458 1046 24 its -PRON- PRP$ 50458 1046 25 cellular cellular JJ 50458 1046 26 envelope envelope NN 50458 1046 27 , , , 50458 1046 28 and and CC 50458 1046 29 does do VBZ 50458 1046 30 not not RB 50458 1046 31 diffuse diffuse VB 50458 1046 32 through through IN 50458 1046 33 this this DT 50458 1046 34 . . . 50458 1047 1 Metchnikoff Metchnikoff NNP 50458 1047 2 and and CC 50458 1047 3 Roux Roux NNP 50458 1047 4 are be VBP 50458 1047 5 of of IN 50458 1047 6 the the DT 50458 1047 7 contrary contrary JJ 50458 1047 8 opinion,[140 opinion,[140 NN 50458 1047 9 ] ] -RRB- 50458 1047 10 however however RB 50458 1047 11 , , , 50458 1047 12 and and CC 50458 1047 13 they -PRON- PRP 50458 1047 14 have have VBP 50458 1047 15 prepared prepare VBN 50458 1047 16 a a DT 50458 1047 17 toxin toxin NN 50458 1047 18 almost almost RB 50458 1047 19 insensitive insensitive JJ 50458 1047 20 to to IN 50458 1047 21 a a DT 50458 1047 22 temperature temperature NN 50458 1047 23 of of IN 50458 1047 24 100 100 CD 50458 1047 25 ° ° NNS 50458 1047 26 C. C. NNP 50458 1047 27 , , , 50458 1047 28 and and CC 50458 1047 29 precipitable precipitable JJ 50458 1047 30 from from IN 50458 1047 31 its -PRON- PRP$ 50458 1047 32 solutions solution NNS 50458 1047 33 by by IN 50458 1047 34 ammonium ammonium NN 50458 1047 35 sulphate sulphate NN 50458 1047 36 or or CC 50458 1047 37 strong strong JJ 50458 1047 38 alcohol alcohol NN 50458 1047 39 ; ; : 50458 1047 40 the the DT 50458 1047 41 toxin toxin NN 50458 1047 42 is be VBZ 50458 1047 43 a a DT 50458 1047 44 toxalbumin toxalbumin NN 50458 1047 45 . . . 50458 1048 1 This this DT 50458 1048 2 toxin toxin NN 50458 1048 3 is be VBZ 50458 1048 4 quite quite RB 50458 1048 5 toxic toxic JJ 50458 1048 6 ; ; : 50458 1048 7 one one CD 50458 1048 8 - - HYPH 50458 1048 9 third third NN 50458 1048 10 of of IN 50458 1048 11 a a DT 50458 1048 12 cubic cubic JJ 50458 1048 13 centimeter centimeter NN 50458 1048 14 suffices suffice VBZ 50458 1048 15 to to TO 50458 1048 16 kill kill VB 50458 1048 17 100 100 CD 50458 1048 18 Gm Gm NNP 50458 1048 19 . . . 50458 1049 1 of of IN 50458 1049 2 guinea guinea NN 50458 1049 3 - - HYPH 50458 1049 4 pig pig NN 50458 1049 5 in in IN 50458 1049 6 18 18 CD 50458 1049 7 hours hour NNS 50458 1049 8 ; ; , 50458 1049 9 with with IN 50458 1049 10 larger large JJR 50458 1049 11 doses dose NNS 50458 1049 12 , , , 50458 1049 13 death death NN 50458 1049 14 is be VBZ 50458 1049 15 almost almost RB 50458 1049 16 immediate immediate JJ 50458 1049 17 . . . 50458 1050 1 [ [ -LRB- 50458 1050 2 139 139 CD 50458 1050 3 ] ] -RRB- 50458 1050 4 _ _ NNP 50458 1050 5 Annal Annal NNP 50458 1050 6 . . . 50458 1051 1 de de NNP 50458 1051 2 l'Instit l'Instit NNP 50458 1051 3 . . . 50458 1052 1 Pasteur Pasteur NNP 50458 1052 2 _ _ NNP 50458 1052 3 , , , 50458 1052 4 IX IX NNP 50458 1052 5 , , , 50458 1052 6 p. p. NN 50458 1052 7 129 129 CD 50458 1052 8 . . . 50458 1053 1 [ [ -LRB- 50458 1053 2 140 140 CD 50458 1053 3 ] ] -RRB- 50458 1053 4 _ _ NNP 50458 1053 5 Ibid Ibid NNP 50458 1053 6 . . . 50458 1053 7 _ _ NNP 50458 1053 8 , , , 50458 1053 9 X X NNP 50458 1053 10 , , , 50458 1053 11 p. p. NN 50458 1053 12 257 257 CD 50458 1053 13 . . . 50458 1054 1 By by IN 50458 1054 2 immunizing immunize VBG 50458 1054 3 guinea guinea NN 50458 1054 4 - - HYPH 50458 1054 5 pigs pig NNS 50458 1054 6 , , , 50458 1054 7 rabbits rabbit NNS 50458 1054 8 , , , 50458 1054 9 and and CC 50458 1054 10 horses horse NNS 50458 1054 11 with with IN 50458 1054 12 this this DT 50458 1054 13 cholera cholera NN 50458 1054 14 toxin toxin NN 50458 1054 15 , , , 50458 1054 16 Metchnikoff Metchnikoff NNP 50458 1054 17 and and CC 50458 1054 18 Roux Roux NNP 50458 1054 19 obtained obtain VBD 50458 1054 20 a a DT 50458 1054 21 serum serum NN 50458 1054 22 which which WDT 50458 1054 23 is be VBZ 50458 1054 24 distinctly distinctly RB 50458 1054 25 antitoxic antitoxic JJ 50458 1054 26 for for IN 50458 1054 27 rabbits rabbit NNS 50458 1054 28 . . . 50458 1055 1 Nothing nothing NN 50458 1055 2 absolutely absolutely RB 50458 1055 3 certain certain JJ 50458 1055 4 has have VBZ 50458 1055 5 been be VBN 50458 1055 6 found find VBN 50458 1055 7 as as IN 50458 1055 8 to to IN 50458 1055 9 its -PRON- PRP$ 50458 1055 10 action action NN 50458 1055 11 on on IN 50458 1055 12 man man NN 50458 1055 13 . . . 50458 1056 1 [ [ -LRB- 50458 1056 2 141 141 CD 50458 1056 3 ] ] -RRB- 50458 1056 4 [ [ -LRB- 50458 1056 5 141 141 CD 50458 1056 6 ] ] -RRB- 50458 1056 7 HAFFKINE haffkine NN 50458 1056 8 : : : 50458 1056 9 _ _ NNP 50458 1056 10 Compt Compt NNP 50458 1056 11 . . . 50458 1057 1 rend rend VB 50458 1057 2 . . . 50458 1058 1 de de NNP 50458 1058 2 l'Acad l'Acad NNP 50458 1058 3 . . . 50458 1059 1 des des NNP 50458 1059 2 Sciences Sciences NNPS 50458 1059 3 _ _ NNP 50458 1059 4 , , , 50458 1059 5 1892 1892 CD 50458 1059 6 ; ; : 50458 1059 7 METCHNIKOFF METCHNIKOFF NNP 50458 1059 8 : : : 50458 1059 9 _ _ NNP 50458 1059 10 Annal Annal NNP 50458 1059 11 . . . 50458 1060 1 de de NNP 50458 1060 2 l'Instit l'Instit NNP 50458 1060 3 . . . 50458 1061 1 Pasteur Pasteur NNP 50458 1061 2 _ _ NNP 50458 1061 3 , , , 50458 1061 4 VII VII NNP 50458 1061 5 , , , 50458 1061 6 p. p. NN 50458 1061 7 403 403 CD 50458 1061 8 ; ; : 50458 1061 9 and and CC 50458 1061 10 ROUX roux VB 50458 1061 11 : : : 50458 1061 12 _ _ NNP 50458 1061 13 Ibid Ibid NNP 50458 1061 14 . . . 50458 1061 15 _ _ NNP 50458 1061 16 , , , 50458 1061 17 X X NNP 50458 1061 18 , , , 50458 1061 19 p. p. NN 50458 1061 20 253 253 CD 50458 1061 21 . . . 50458 1062 1 * * NFP 50458 1062 2 * * NFP 50458 1062 3 * * NFP 50458 1062 4 * * NFP 50458 1062 5 * * NFP 50458 1062 6 We -PRON- PRP 50458 1062 7 will will MD 50458 1062 8 not not RB 50458 1062 9 dwell dwell VB 50458 1062 10 longer long RBR 50458 1062 11 here here RB 50458 1062 12 on on IN 50458 1062 13 the the DT 50458 1062 14 toxins toxin NNS 50458 1062 15 of of IN 50458 1062 16 microbial microbial JJ 50458 1062 17 origin origin NN 50458 1062 18 . . . 50458 1063 1 It -PRON- PRP 50458 1063 2 appears appear VBZ 50458 1063 3 evident evident JJ 50458 1063 4 , , , 50458 1063 5 however however RB 50458 1063 6 , , , 50458 1063 7 from from IN 50458 1063 8 what what WP 50458 1063 9 has have VBZ 50458 1063 10 been be VBN 50458 1063 11 stated state VBN 50458 1063 12 above above RB 50458 1063 13 , , , 50458 1063 14 that that IN 50458 1063 15 the the DT 50458 1063 16 great great JJ 50458 1063 17 majority majority NN 50458 1063 18 , , , 50458 1063 19 if if IN 50458 1063 20 not not RB 50458 1063 21 all all DT 50458 1063 22 , , , 50458 1063 23 of of IN 50458 1063 24 the the DT 50458 1063 25 virulent virulent NN 50458 1063 26 microbes microbe NNS 50458 1063 27 manifest manifest VBP 50458 1063 28 their -PRON- PRP$ 50458 1063 29 virulence virulence NN 50458 1063 30 by by IN 50458 1063 31 means mean NNS 50458 1063 32 of of IN 50458 1063 33 toxic toxic JJ 50458 1063 34 secretions secretion NNS 50458 1063 35 . . . 50458 1064 1 Almost almost RB 50458 1064 2 every every DT 50458 1064 3 one one CD 50458 1064 4 of of IN 50458 1064 5 these these DT 50458 1064 6 toxins toxin NNS 50458 1064 7 has have VBZ 50458 1064 8 been be VBN 50458 1064 9 the the DT 50458 1064 10 subject subject NN 50458 1064 11 of of IN 50458 1064 12 study study NN 50458 1064 13 . . . 50458 1065 1 They -PRON- PRP 50458 1065 2 would would MD 50458 1065 3 otherwise otherwise RB 50458 1065 4 not not RB 50458 1065 5 have have VB 50458 1065 6 interested interest VBN 50458 1065 7 us -PRON- PRP 50458 1065 8 here here RB 50458 1065 9 , , , 50458 1065 10 where where WRB 50458 1065 11 our -PRON- PRP$ 50458 1065 12 main main JJ 50458 1065 13 object object NN 50458 1065 14 was be VBD 50458 1065 15 but but CC 50458 1065 16 to to TO 50458 1065 17 dwell dwell VB 50458 1065 18 upon upon IN 50458 1065 19 the the DT 50458 1065 20 general general JJ 50458 1065 21 properties property NNS 50458 1065 22 . . . 50458 1066 1 CHAPTER CHAPTER NNP 50458 1066 2 V. V. NNP 50458 1066 3 THE the DT 50458 1066 4 VENOMS VENOMS NNP 50458 1066 5 . . . 50458 1067 1 = = NFP 50458 1067 2 General General NNP 50458 1067 3 Nature Nature NNP 50458 1067 4 of of IN 50458 1067 5 Venoms.=--The Venoms.=--The NNP 50458 1067 6 venoms venom NNS 50458 1067 7 are be VBP 50458 1067 8 more more RBR 50458 1067 9 or or CC 50458 1067 10 less less JJR 50458 1067 11 toxic toxic JJ 50458 1067 12 products product NNS 50458 1067 13 secreted secrete VBN 50458 1067 14 by by IN 50458 1067 15 certain certain JJ 50458 1067 16 reptiles reptile NNS 50458 1067 17 , , , 50458 1067 18 batrachians batrachian NNS 50458 1067 19 , , , 50458 1067 20 and and CC 50458 1067 21 fish fish NN 50458 1067 22 ; ; : 50458 1067 23 by by IN 50458 1067 24 a a DT 50458 1067 25 large large JJ 50458 1067 26 number number NN 50458 1067 27 of of IN 50458 1067 28 invertebrates invertebrate NNS 50458 1067 29 ; ; : 50458 1067 30 by by IN 50458 1067 31 arachnids arachnid NNS 50458 1067 32 , , , 50458 1067 33 apids apid NNS 50458 1067 34 , , , 50458 1067 35 scorpionids scorpionid NNS 50458 1067 36 , , , 50458 1067 37 araneids araneid NNS 50458 1067 38 , , , 50458 1067 39 and and CC 50458 1067 40 a a DT 50458 1067 41 large large JJ 50458 1067 42 number number NN 50458 1067 43 of of IN 50458 1067 44 other other JJ 50458 1067 45 insects insect NNS 50458 1067 46 . . . 50458 1068 1 The the DT 50458 1068 2 venoms venom NNS 50458 1068 3 are be VBP 50458 1068 4 toxic toxic JJ 50458 1068 5 principles principle NNS 50458 1068 6 very very RB 50458 1068 7 closely closely RB 50458 1068 8 allied allied JJ 50458 1068 9 to to IN 50458 1068 10 the the DT 50458 1068 11 microbial microbial JJ 50458 1068 12 toxins toxin NNS 50458 1068 13 ; ; : 50458 1068 14 like like IN 50458 1068 15 the the DT 50458 1068 16 latter latter JJ 50458 1068 17 , , , 50458 1068 18 they -PRON- PRP 50458 1068 19 form form VBP 50458 1068 20 two two CD 50458 1068 21 classes class NNS 50458 1068 22 , , , 50458 1068 23 the the DT 50458 1068 24 one one CD 50458 1068 25 alkaloidal alkaloidal NN 50458 1068 26 , , , 50458 1068 27 the the DT 50458 1068 28 other other JJ 50458 1068 29 proteid proteid NN 50458 1068 30 , , , 50458 1068 31 possessing possess VBG 50458 1068 32 a a DT 50458 1068 33 true true JJ 50458 1068 34 diastatic diastatic JJ 50458 1068 35 character character NN 50458 1068 36 . . . 50458 1069 1 They -PRON- PRP 50458 1069 2 closely closely RB 50458 1069 3 resemble resemble VBP 50458 1069 4 the the DT 50458 1069 5 microbial microbial NN 50458 1069 6 toxins toxin NNS 50458 1069 7 , , , 50458 1069 8 moreover moreover RB 50458 1069 9 , , , 50458 1069 10 by by IN 50458 1069 11 the the DT 50458 1069 12 fact fact NN 50458 1069 13 that that IN 50458 1069 14 they -PRON- PRP 50458 1069 15 are be VBP 50458 1069 16 capable capable JJ 50458 1069 17 of of IN 50458 1069 18 being be VBG 50458 1069 19 transformed transform VBN 50458 1069 20 into into IN 50458 1069 21 vaccins vaccin NNS 50458 1069 22 by by IN 50458 1069 23 attenuation attenuation NN 50458 1069 24 of of IN 50458 1069 25 their -PRON- PRP$ 50458 1069 26 virulence virulence NN 50458 1069 27 , , , 50458 1069 28 by by IN 50458 1069 29 the the DT 50458 1069 30 action action NN 50458 1069 31 of of IN 50458 1069 32 heat heat NN 50458 1069 33 or or CC 50458 1069 34 chemical chemical NN 50458 1069 35 reagents reagent NNS 50458 1069 36 , , , 50458 1069 37 and and CC 50458 1069 38 of of IN 50458 1069 39 leading lead VBG 50458 1069 40 to to IN 50458 1069 41 habituation habituation NN 50458 1069 42 of of IN 50458 1069 43 use use NN 50458 1069 44 and and CC 50458 1069 45 the the DT 50458 1069 46 conference conference NN 50458 1069 47 of of IN 50458 1069 48 immunity immunity NN 50458 1069 49 . . . 50458 1070 1 [ [ -LRB- 50458 1070 2 142 142 CD 50458 1070 3 ] ] -RRB- 50458 1070 4 Moreover moreover RB 50458 1070 5 , , , 50458 1070 6 like like IN 50458 1070 7 the the DT 50458 1070 8 various various JJ 50458 1070 9 viruses virus NNS 50458 1070 10 , , , 50458 1070 11 the the DT 50458 1070 12 serum serum NN 50458 1070 13 of of IN 50458 1070 14 immunized immunized JJ 50458 1070 15 animals animal NNS 50458 1070 16 is be VBZ 50458 1070 17 antivenomous antivenomous JJ 50458 1070 18 , , , 50458 1070 19 so so IN 50458 1070 20 that that IN 50458 1070 21 if if IN 50458 1070 22 injected inject VBN 50458 1070 23 into into IN 50458 1070 24 the the DT 50458 1070 25 veins vein NNS 50458 1070 26 or or CC 50458 1070 27 beneath beneath IN 50458 1070 28 the the DT 50458 1070 29 skin skin NN 50458 1070 30 of of IN 50458 1070 31 non non JJ 50458 1070 32 - - JJ 50458 1070 33 immunized immunized JJ 50458 1070 34 animals animal NNS 50458 1070 35 , , , 50458 1070 36 the the DT 50458 1070 37 serum serum NN 50458 1070 38 confers confer VBZ 50458 1070 39 upon upon IN 50458 1070 40 them -PRON- PRP 50458 1070 41 an an DT 50458 1070 42 immunity immunity NN 50458 1070 43 against against IN 50458 1070 44 venom venom NN 50458 1070 45 which which WDT 50458 1070 46 lasts last VBZ 50458 1070 47 for for IN 50458 1070 48 some some DT 50458 1070 49 time time NN 50458 1070 50 . . . 50458 1071 1 [ [ -LRB- 50458 1071 2 142 142 CD 50458 1071 3 ] ] -RRB- 50458 1071 4 _ _ NNP 50458 1071 5 Annal Annal NNP 50458 1071 6 . . . 50458 1072 1 de de NNP 50458 1072 2 l'Instit l'Instit NNP 50458 1072 3 . . . 50458 1073 1 Pasteur Pasteur NNP 50458 1073 2 _ _ NNP 50458 1073 3 , , , 50458 1073 4 VIII VIII NNP 50458 1073 5 , , , 50458 1073 6 p. p. NN 50458 1073 7 281 281 CD 50458 1073 8 ; ; : 50458 1073 9 _ _ NNP 50458 1073 10 Journ Journ NNP 50458 1073 11 . . . 50458 1074 1 of of IN 50458 1074 2 Physiol Physiol NNP 50458 1074 3 . . . 50458 1074 4 _ _ NNP 50458 1074 5 , , , 50458 1074 6 VIII VIII NNP 50458 1074 7 , , , 50458 1074 8 p. p. NN 50458 1074 9 203 203 CD 50458 1074 10 ; ; : 50458 1074 11 and and CC 50458 1074 12 _ _ NNP 50458 1074 13 Soc Soc NNP 50458 1074 14 . . . 50458 1075 1 de de NNP 50458 1075 2 Biol Biol NNP 50458 1075 3 . . . 50458 1075 4 _ _ NNP 50458 1075 5 , , , 50458 1075 6 1894 1894 CD 50458 1075 7 , , , 50458 1075 8 p. p. NN 50458 1075 9 111 111 CD 50458 1075 10 . . . 50458 1076 1 These these DT 50458 1076 2 venoms venom NNS 50458 1076 3 , , , 50458 1076 4 like like IN 50458 1076 5 the the DT 50458 1076 6 microbial microbial JJ 50458 1076 7 toxins toxin NNS 50458 1076 8 , , , 50458 1076 9 possess possess NN 50458 1076 10 but but CC 50458 1076 11 slight slight JJ 50458 1076 12 toxicity toxicity NN 50458 1076 13 when when WRB 50458 1076 14 absorbed absorb VBN 50458 1076 15 via via IN 50458 1076 16 the the DT 50458 1076 17 stomach stomach NN 50458 1076 18 . . . 50458 1077 1 Fraser Fraser NNP 50458 1077 2 , , , 50458 1077 3 utilizing utilize VBG 50458 1077 4 a a DT 50458 1077 5 method method NN 50458 1077 6 previously previously RB 50458 1077 7 advocated advocate VBN 50458 1077 8 , , , 50458 1077 9 succeeded succeed VBD 50458 1077 10 , , , 50458 1077 11 by by IN 50458 1077 12 following follow VBG 50458 1077 13 this this DT 50458 1077 14 method method NN 50458 1077 15 , , , 50458 1077 16 in in IN 50458 1077 17 vaccinating vaccinate VBG 50458 1077 18 against against IN 50458 1077 19 serpent serpent NN 50458 1077 20 - - HYPH 50458 1077 21 venom venom NN 50458 1077 22 by by IN 50458 1077 23 causing cause VBG 50458 1077 24 the the DT 50458 1077 25 absorption absorption NN 50458 1077 26 by by IN 50458 1077 27 animals animal NNS 50458 1077 28 of of IN 50458 1077 29 constantly constantly RB 50458 1077 30 increasing increase VBG 50458 1077 31 doses dose NNS 50458 1077 32 of of IN 50458 1077 33 venom venom NN 50458 1077 34 . . . 50458 1078 1 It -PRON- PRP 50458 1078 2 was be VBD 50458 1078 3 thus thus RB 50458 1078 4 possible possible JJ 50458 1078 5 to to TO 50458 1078 6 make make VB 50458 1078 7 the the DT 50458 1078 8 animals animal NNS 50458 1078 9 withstand withstand VB 50458 1078 10 doses dose NNS 50458 1078 11 a a DT 50458 1078 12 thousand thousand CD 50458 1078 13 times time NNS 50458 1078 14 greater great JJR 50458 1078 15 than than IN 50458 1078 16 the the DT 50458 1078 17 ordinary ordinary JJ 50458 1078 18 lethal lethal JJ 50458 1078 19 dose dose NN 50458 1078 20 ; ; : 50458 1078 21 the the DT 50458 1078 22 blood blood NN 50458 1078 23 and and CC 50458 1078 24 serums serum NNS 50458 1078 25 of of IN 50458 1078 26 these these DT 50458 1078 27 animals animal NNS 50458 1078 28 at at IN 50458 1078 29 this this DT 50458 1078 30 point point NN 50458 1078 31 possessed possess VBD 50458 1078 32 immunizing immunize VBG 50458 1078 33 properties property NNS 50458 1078 34 , , , 50458 1078 35 and and CC 50458 1078 36 this this DT 50458 1078 37 property property NN 50458 1078 38 passed pass VBN 50458 1078 39 by by IN 50458 1078 40 heredity heredity NN 50458 1078 41 to to IN 50458 1078 42 the the DT 50458 1078 43 offspring offspring NN 50458 1078 44 , , , 50458 1078 45 to to TO 50458 1078 46 which which WDT 50458 1078 47 it -PRON- PRP 50458 1078 48 is be VBZ 50458 1078 49 transmitted transmit VBN 50458 1078 50 by by IN 50458 1078 51 the the DT 50458 1078 52 blood blood NN 50458 1078 53 itself -PRON- PRP 50458 1078 54 , , , 50458 1078 55 and and CC 50458 1078 56 by by IN 50458 1078 57 the the DT 50458 1078 58 milk milk NN 50458 1078 59 during during IN 50458 1078 60 feeding feed VBG 50458 1078 61 . . . 50458 1079 1 Along along IN 50458 1079 2 with with IN 50458 1079 3 these these DT 50458 1079 4 resemblances resemblance NNS 50458 1079 5 between between IN 50458 1079 6 the the DT 50458 1079 7 venoms venom NNS 50458 1079 8 and and CC 50458 1079 9 toxins toxin NNS 50458 1079 10 , , , 50458 1079 11 attention attention NN 50458 1079 12 must must MD 50458 1079 13 be be VB 50458 1079 14 called call VBN 50458 1079 15 to to IN 50458 1079 16 a a DT 50458 1079 17 very very RB 50458 1079 18 important important JJ 50458 1079 19 difference difference NN 50458 1079 20 . . . 50458 1080 1 As as IN 50458 1080 2 we -PRON- PRP 50458 1080 3 have have VBP 50458 1080 4 already already RB 50458 1080 5 seen see VBN 50458 1080 6 , , , 50458 1080 7 the the DT 50458 1080 8 action action NN 50458 1080 9 of of IN 50458 1080 10 the the DT 50458 1080 11 toxins toxin NNS 50458 1080 12 on on IN 50458 1080 13 the the DT 50458 1080 14 organism organism NN 50458 1080 15 is be VBZ 50458 1080 16 always always RB 50458 1080 17 preceded precede VBN 50458 1080 18 by by IN 50458 1080 19 a a DT 50458 1080 20 certain certain JJ 50458 1080 21 period period NN 50458 1080 22 of of IN 50458 1080 23 incubation incubation NN 50458 1080 24 ; ; , 50458 1080 25 the the DT 50458 1080 26 action action NN 50458 1080 27 of of IN 50458 1080 28 the the DT 50458 1080 29 venoms venom NNS 50458 1080 30 , , , 50458 1080 31 on on IN 50458 1080 32 the the DT 50458 1080 33 contrary contrary NN 50458 1080 34 , , , 50458 1080 35 is be VBZ 50458 1080 36 almost almost RB 50458 1080 37 instantaneous instantaneous JJ 50458 1080 38 , , , 50458 1080 39 and and CC 50458 1080 40 in in IN 50458 1080 41 this this DT 50458 1080 42 respect respect NN 50458 1080 43 they -PRON- PRP 50458 1080 44 behave behave VBP 50458 1080 45 like like UH 50458 1080 46 chemical chemical JJ 50458 1080 47 agents agent NNS 50458 1080 48 and and CC 50458 1080 49 alkaloidal alkaloidal NN 50458 1080 50 toxins toxin NNS 50458 1080 51 . . . 50458 1081 1 If if IN 50458 1081 2 the the DT 50458 1081 3 venoms venom NNS 50458 1081 4 are be VBP 50458 1081 5 preserved preserve VBN 50458 1081 6 in in IN 50458 1081 7 a a DT 50458 1081 8 moist moist JJ 50458 1081 9 condition condition NN 50458 1081 10 , , , 50458 1081 11 they -PRON- PRP 50458 1081 12 change change VBP 50458 1081 13 because because IN 50458 1081 14 they -PRON- PRP 50458 1081 15 undergo undergo VBP 50458 1081 16 putrefaction putrefaction NN 50458 1081 17 , , , 50458 1081 18 which which WDT 50458 1081 19 is be VBZ 50458 1081 20 generally generally RB 50458 1081 21 the the DT 50458 1081 22 case case NN 50458 1081 23 with with IN 50458 1081 24 all all DT 50458 1081 25 diastatic diastatic JJ 50458 1081 26 substances substance NNS 50458 1081 27 , , , 50458 1081 28 and and CC 50458 1081 29 particularly particularly RB 50458 1081 30 the the DT 50458 1081 31 toxins toxin NNS 50458 1081 32 . . . 50458 1082 1 It -PRON- PRP 50458 1082 2 is be VBZ 50458 1082 3 interesting interesting JJ 50458 1082 4 to to TO 50458 1082 5 note note VB 50458 1082 6 that that IN 50458 1082 7 animals animal NNS 50458 1082 8 which which WDT 50458 1082 9 have have VBP 50458 1082 10 been be VBN 50458 1082 11 bitten bite VBN 50458 1082 12 by by IN 50458 1082 13 a a DT 50458 1082 14 venomous venomous JJ 50458 1082 15 serpent serpent NN 50458 1082 16 , , , 50458 1082 17 but but CC 50458 1082 18 which which WDT 50458 1082 19 , , , 50458 1082 20 for for IN 50458 1082 21 some some DT 50458 1082 22 reason reason NN 50458 1082 23 or or CC 50458 1082 24 other other JJ 50458 1082 25 , , , 50458 1082 26 have have VBP 50458 1082 27 not not RB 50458 1082 28 succumbed succumb VBN 50458 1082 29 to to IN 50458 1082 30 the the DT 50458 1082 31 venom venom NN 50458 1082 32 , , , 50458 1082 33 never never RB 50458 1082 34 recover recover VBP 50458 1082 35 their -PRON- PRP$ 50458 1082 36 former former JJ 50458 1082 37 condition condition NN 50458 1082 38 ; ; : 50458 1082 39 if if IN 50458 1082 40 they -PRON- PRP 50458 1082 41 were be VBD 50458 1082 42 young young JJ 50458 1082 43 , , , 50458 1082 44 their -PRON- PRP$ 50458 1082 45 functions function NNS 50458 1082 46 cease cease VBP 50458 1082 47 to to TO 50458 1082 48 develop develop VB 50458 1082 49 , , , 50458 1082 50 and and CC 50458 1082 51 they -PRON- PRP 50458 1082 52 droop droop VBP 50458 1082 53 ; ; : 50458 1082 54 if if IN 50458 1082 55 they -PRON- PRP 50458 1082 56 are be VBP 50458 1082 57 adults adult NNS 50458 1082 58 , , , 50458 1082 59 their -PRON- PRP$ 50458 1082 60 general general JJ 50458 1082 61 condition condition NN 50458 1082 62 remains remain VBZ 50458 1082 63 that that DT 50458 1082 64 of of IN 50458 1082 65 stupefaction stupefaction NN 50458 1082 66 . . . 50458 1083 1 = = NFP 50458 1083 2 Venomous venomous JJ 50458 1083 3 Serpents.=--Among Serpents.=--Among . 50458 1083 4 the the DT 50458 1083 5 venomous venomous JJ 50458 1083 6 serpents,[143 serpents,[143 NNP 50458 1083 7 ] ] -RRB- 50458 1083 8 the the DT 50458 1083 9 most most RBS 50458 1083 10 important important JJ 50458 1083 11 as as RB 50458 1083 12 well well RB 50458 1083 13 as as IN 50458 1083 14 the the DT 50458 1083 15 most most RBS 50458 1083 16 dangerous dangerous JJ 50458 1083 17 are be VBP 50458 1083 18 the the DT 50458 1083 19 following follow VBG 50458 1083 20 : : : 50458 1083 21 Cobra cobra VB 50458 1083 22 di di FW 50458 1083 23 capello capello NN 50458 1083 24 ( ( -LRB- 50458 1083 25 Naja Naja NNP 50458 1083 26 tripudians tripudian NNS 50458 1083 27 , , , 50458 1083 28 the the DT 50458 1083 29 hooded hood VBN 50458 1083 30 cobra cobra NN 50458 1083 31 ) ) -RRB- 50458 1083 32 and and CC 50458 1083 33 its -PRON- PRP$ 50458 1083 34 analogues analogue NNS 50458 1083 35 , , , 50458 1083 36 the the DT 50458 1083 37 black black JJ 50458 1083 38 Naja Naja NNP 50458 1083 39 , , , 50458 1083 40 Naja Naja NNP 50458 1083 41 hagé hagé NN 50458 1083 42 , , , 50458 1083 43 etc etc FW 50458 1083 44 . . . 50458 1084 1 ; ; : 50458 1084 2 the the DT 50458 1084 3 elops elop NNS 50458 1084 4 ( ( -LRB- 50458 1084 5 coral coral JJ 50458 1084 6 serpent serpent NN 50458 1084 7 ) ) -RRB- 50458 1084 8 ; ; : 50458 1084 9 the the DT 50458 1084 10 bungurus bungurus NN 50458 1084 11 of of IN 50458 1084 12 Bengal Bengal NNP 50458 1084 13 and and CC 50458 1084 14 Burmah Burmah NNP 50458 1084 15 ; ; : 50458 1084 16 the the DT 50458 1084 17 Platycercus platycercus JJ 50458 1084 18 proteroglyphia proteroglyphia NN 50458 1084 19 , , , 50458 1084 20 which which WDT 50458 1084 21 is be VBZ 50458 1084 22 found find VBN 50458 1084 23 chiefly chiefly RB 50458 1084 24 in in IN 50458 1084 25 the the DT 50458 1084 26 waters water NNS 50458 1084 27 of of IN 50458 1084 28 the the DT 50458 1084 29 Indian Indian NNP 50458 1084 30 Ocean Ocean NNP 50458 1084 31 ; ; : 50458 1084 32 the the DT 50458 1084 33 crotalian crotalian JJ 50458 1084 34 solenoglyphs solenoglyphs NN 50458 1084 35 of of IN 50458 1084 36 the the DT 50458 1084 37 two two CD 50458 1084 38 Americas Americas NNPS 50458 1084 39 , , , 50458 1084 40 and and CC 50458 1084 41 among among IN 50458 1084 42 which which WDT 50458 1084 43 in in IN 50458 1084 44 particular particular JJ 50458 1084 45 are be VBP 50458 1084 46 the the DT 50458 1084 47 rattlesnake rattlesnake NN 50458 1084 48 , , , 50458 1084 49 the the DT 50458 1084 50 fer fer JJ 50458 1084 51 - - HYPH 50458 1084 52 de de NN 50458 1084 53 - - HYPH 50458 1084 54 lance lance NNP 50458 1084 55 ( ( -LRB- 50458 1084 56 the the DT 50458 1084 57 yellow yellow JJ 50458 1084 58 viper viper NN 50458 1084 59 ) ) -RRB- 50458 1084 60 of of IN 50458 1084 61 Martinique Martinique NNP 50458 1084 62 ; ; : 50458 1084 63 the the DT 50458 1084 64 surucucu surucucu NN 50458 1084 65 of of IN 50458 1084 66 Guiana Guiana NNP 50458 1084 67 ; ; : 50458 1084 68 and and CC 50458 1084 69 the the DT 50458 1084 70 moccasins moccasin NNS 50458 1084 71 and and CC 50458 1084 72 copperheads copperhead NNS 50458 1084 73 of of IN 50458 1084 74 Texas Texas NNP 50458 1084 75 and and CC 50458 1084 76 Florida Florida NNP 50458 1084 77 . . . 50458 1085 1 Lastly lastly RB 50458 1085 2 , , , 50458 1085 3 the the DT 50458 1085 4 entire entire JJ 50458 1085 5 group group NN 50458 1085 6 of of IN 50458 1085 7 viperian viperian JJ 50458 1085 8 solenoglyphs solenoglyph NNS 50458 1085 9 , , , 50458 1085 10 among among IN 50458 1085 11 which which WDT 50458 1085 12 are be VBP 50458 1085 13 the the DT 50458 1085 14 Echidnæ Echidnæ NNP 50458 1085 15 , , , 50458 1085 16 the the DT 50458 1085 17 bite bite NN 50458 1085 18 of of IN 50458 1085 19 some some DT 50458 1085 20 of of IN 50458 1085 21 which which WDT 50458 1085 22 , , , 50458 1085 23 for for IN 50458 1085 24 instance instance NN 50458 1085 25 the the DT 50458 1085 26 daboia daboia NN 50458 1085 27 or or CC 50458 1085 28 echidna echidna NN 50458 1085 29 , , , 50458 1085 30 is be VBZ 50458 1085 31 dreadful dreadful JJ 50458 1085 32 ; ; : 50458 1085 33 the the DT 50458 1085 34 African african JJ 50458 1085 35 vipers viper NNS 50458 1085 36 , , , 50458 1085 37 among among IN 50458 1085 38 which which WDT 50458 1085 39 may may MD 50458 1085 40 be be VB 50458 1085 41 mentioned mention VBN 50458 1085 42 the the DT 50458 1085 43 horned horned JJ 50458 1085 44 viper viper NN 50458 1085 45 , , , 50458 1085 46 the the DT 50458 1085 47 bite bite NN 50458 1085 48 of of IN 50458 1085 49 which which WDT 50458 1085 50 will will MD 50458 1085 51 kill kill VB 50458 1085 52 a a DT 50458 1085 53 camel camel NN 50458 1085 54 ; ; : 50458 1085 55 the the DT 50458 1085 56 springing springing NN 50458 1085 57 viper viper NN 50458 1085 58 of of IN 50458 1085 59 Congo Congo NNP 50458 1085 60 , , , 50458 1085 61 and and CC 50458 1085 62 the the DT 50458 1085 63 rhinoceros rhinoceros NN 50458 1085 64 - - HYPH 50458 1085 65 viper viper NN 50458 1085 66 of of IN 50458 1085 67 Gabun Gabun NNP 50458 1085 68 ; ; : 50458 1085 69 the the DT 50458 1085 70 European european JJ 50458 1085 71 vipers viper NNS 50458 1085 72 , , , 50458 1085 73 the the DT 50458 1085 74 most most RBS 50458 1085 75 dangerous dangerous JJ 50458 1085 76 of of IN 50458 1085 77 which which WDT 50458 1085 78 is be VBZ 50458 1085 79 certainly certainly RB 50458 1085 80 the the DT 50458 1085 81 asp asp NN 50458 1085 82 of of IN 50458 1085 83 France France NNP 50458 1085 84 , , , 50458 1085 85 which which WDT 50458 1085 86 is be VBZ 50458 1085 87 exceedingly exceedingly RB 50458 1085 88 numerous numerous JJ 50458 1085 89 in in IN 50458 1085 90 certain certain JJ 50458 1085 91 regions region NNS 50458 1085 92 . . . 50458 1086 1 [ [ -LRB- 50458 1086 2 143 143 CD 50458 1086 3 ] ] -RRB- 50458 1086 4 CALMETTE calmette NN 50458 1086 5 : : : 50458 1086 6 _ _ NNP 50458 1086 7 Le Le NNP 50458 1086 8 Venin Venin NNP 50458 1086 9 des des NNP 50458 1086 10 Serpents Serpents NNP 50458 1086 11 _ _ NNP 50458 1086 12 , , , 50458 1086 13 Paris Paris NNP 50458 1086 14 , , , 50458 1086 15 1896 1896 CD 50458 1086 16 . . . 50458 1087 1 The the DT 50458 1087 2 effects effect NNS 50458 1087 3 of of IN 50458 1087 4 the the DT 50458 1087 5 bites bite NNS 50458 1087 6 of of IN 50458 1087 7 venomous venomous JJ 50458 1087 8 serpents serpent NNS 50458 1087 9 on on IN 50458 1087 10 man man NN 50458 1087 11 and and CC 50458 1087 12 animals animal NNS 50458 1087 13 are be VBP 50458 1087 14 generally generally RB 50458 1087 15 well well RB 50458 1087 16 known known JJ 50458 1087 17 to to IN 50458 1087 18 the the DT 50458 1087 19 public public NN 50458 1087 20 ; ; : 50458 1087 21 it -PRON- PRP 50458 1087 22 is be VBZ 50458 1087 23 well well JJ 50458 1087 24 to to TO 50458 1087 25 recall recall VB 50458 1087 26 them -PRON- PRP 50458 1087 27 , , , 50458 1087 28 nevertheless nevertheless RB 50458 1087 29 . . . 50458 1088 1 From from IN 50458 1088 2 the the DT 50458 1088 3 moment moment NN 50458 1088 4 the the DT 50458 1088 5 bite bite NN 50458 1088 6 has have VBZ 50458 1088 7 been be VBN 50458 1088 8 inflicted inflict VBN 50458 1088 9 , , , 50458 1088 10 complete complete JJ 50458 1088 11 symptoms symptom NNS 50458 1088 12 of of IN 50458 1088 13 poisoning poisoning NN 50458 1088 14 develop develop NN 50458 1088 15 , , , 50458 1088 16 attended attend VBN 50458 1088 17 by by IN 50458 1088 18 a a DT 50458 1088 19 condition condition NN 50458 1088 20 of of IN 50458 1088 21 extreme extreme JJ 50458 1088 22 and and CC 50458 1088 23 increasing increase VBG 50458 1088 24 weakness weakness NN 50458 1088 25 , , , 50458 1088 26 with with IN 50458 1088 27 vomiting vomiting NN 50458 1088 28 , , , 50458 1088 29 hemorrhage hemorrhage NN 50458 1088 30 , , , 50458 1088 31 and and CC 50458 1088 32 decomposition decomposition NN 50458 1088 33 of of IN 50458 1088 34 the the DT 50458 1088 35 blood blood NN 50458 1088 36 . . . 50458 1089 1 There there EX 50458 1089 2 are be VBP 50458 1089 3 , , , 50458 1089 4 besides besides RB 50458 1089 5 , , , 50458 1089 6 particular particular JJ 50458 1089 7 effects effect NNS 50458 1089 8 which which WDT 50458 1089 9 vary vary VBP 50458 1089 10 with with IN 50458 1089 11 every every DT 50458 1089 12 venom venom NN 50458 1089 13 . . . 50458 1090 1 The the DT 50458 1090 2 following follow VBG 50458 1090 3 table table NN 50458 1090 4 by by IN 50458 1090 5 Calmette[144 Calmette[144 NNP 50458 1090 6 ] ] -RRB- 50458 1090 7 gives give VBZ 50458 1090 8 the the DT 50458 1090 9 comparative comparative JJ 50458 1090 10 toxicity toxicity NN 50458 1090 11 of of IN 50458 1090 12 various various JJ 50458 1090 13 venoms venom NNS 50458 1090 14 , , , 50458 1090 15 taking take VBG 50458 1090 16 as as IN 50458 1090 17 the the DT 50458 1090 18 standard standard NN 50458 1090 19 of of IN 50458 1090 20 comparison comparison NN 50458 1090 21 the the DT 50458 1090 22 quantity quantity NN 50458 1090 23 sufficient sufficient JJ 50458 1090 24 to to TO 50458 1090 25 kill kill VB 50458 1090 26 a a DT 50458 1090 27 rabbit rabbit NN 50458 1090 28 in in IN 50458 1090 29 three three CD 50458 1090 30 or or CC 50458 1090 31 four four CD 50458 1090 32 hours hour NNS 50458 1090 33 : : : 50458 1090 34 Naja Naja NNP 50458 1090 35 tripudians tripudian VBZ 50458 1090 36 0.00047 0.00047 CD 50458 1090 37 Naja Naja NNP 50458 1090 38 hagé hagé NN 50458 1090 39 0.0003 0.0003 CD 50458 1090 40 - - : 50458 1090 41 0.0007 0.0007 CD 50458 1090 42 Acanthophis Acanthophis NNP 50458 1090 43 antarctica antarctica NN 50458 1090 44 0.001 0.001 CD 50458 1090 45 Ceraste Ceraste NNP 50458 1090 46 0.0017 0.0017 CD 50458 1090 47 - - HYPH 50458 1090 48 0.0021 0.0021 CD 50458 1090 49 Haplocephalus haplocephalus JJ 50458 1090 50 variegatus variegatus NN 50458 1090 51 0.0025 0.0025 CD 50458 1090 52 Trigonocephalus trigonocephalus JJ 50458 1090 53 0.0025 0.0025 NNS 50458 1090 54 [ [ -LRB- 50458 1090 55 144 144 CD 50458 1090 56 ] ] -RRB- 50458 1090 57 CALMETTE CALMETTE NNP 50458 1090 58 : : : 50458 1090 59 _ _ NNP 50458 1090 60 Annal Annal NNP 50458 1090 61 . . . 50458 1091 1 Instit Instit NNP 50458 1091 2 . . . 50458 1092 1 Pasteur Pasteur NNP 50458 1092 2 _ _ NNP 50458 1092 3 , , , 50458 1092 4 VIII VIII NNP 50458 1092 5 , , , 50458 1092 6 p. p. NN 50458 1092 7 276 276 CD 50458 1092 8 ; ; : 50458 1092 9 IX IX NNP 50458 1092 10 , , , 50458 1092 11 p. p. NN 50458 1092 12 229 229 CD 50458 1092 13 . . . 50458 1093 1 = = NFP 50458 1093 2 Nature nature NN 50458 1093 3 of of IN 50458 1093 4 Serpent Serpent NNP 50458 1093 5 - - HYPH 50458 1093 6 venoms.=--These venoms.=--These NNS 50458 1093 7 venoms venom NNS 50458 1093 8 are be VBP 50458 1093 9 homogeneous homogeneous JJ 50458 1093 10 liquids liquid NNS 50458 1093 11 , , , 50458 1093 12 somewhat somewhat RB 50458 1093 13 more more RBR 50458 1093 14 dense dense JJ 50458 1093 15 than than IN 50458 1093 16 water water NN 50458 1093 17 , , , 50458 1093 18 in in IN 50458 1093 19 which which WDT 50458 1093 20 they -PRON- PRP 50458 1093 21 are be VBP 50458 1093 22 soluble soluble JJ 50458 1093 23 , , , 50458 1093 24 slightly slightly RB 50458 1093 25 colored color VBN 50458 1093 26 green green JJ 50458 1093 27 or or CC 50458 1093 28 yellow yellow JJ 50458 1093 29 , , , 50458 1093 30 transparent transparent JJ 50458 1093 31 , , , 50458 1093 32 and and CC 50458 1093 33 insoluble insoluble JJ 50458 1093 34 in in IN 50458 1093 35 alcohol alcohol NN 50458 1093 36 ; ; : 50458 1093 37 they -PRON- PRP 50458 1093 38 contain contain VBP 50458 1093 39 from from IN 50458 1093 40 30 30 CD 50458 1093 41 to to TO 50458 1093 42 35 35 CD 50458 1093 43 per per NN 50458 1093 44 cent cent NN 50458 1093 45 . . . 50458 1094 1 of of IN 50458 1094 2 solid solid JJ 50458 1094 3 matter matter NN 50458 1094 4 . . . 50458 1095 1 When when WRB 50458 1095 2 fresh fresh JJ 50458 1095 3 , , , 50458 1095 4 they -PRON- PRP 50458 1095 5 have have VBP 50458 1095 6 a a DT 50458 1095 7 slightly slightly RB 50458 1095 8 acid acid JJ 50458 1095 9 reaction reaction NN 50458 1095 10 . . . 50458 1096 1 Towards towards IN 50458 1096 2 chemical chemical NN 50458 1096 3 reagents reagent NNS 50458 1096 4 , , , 50458 1096 5 and and CC 50458 1096 6 particularly particularly RB 50458 1096 7 acids acid NNS 50458 1096 8 , , , 50458 1096 9 they -PRON- PRP 50458 1096 10 behave behave VBP 50458 1096 11 like like IN 50458 1096 12 albuminoids albuminoid NNS 50458 1096 13 ; ; , 50458 1096 14 almost almost RB 50458 1096 15 all all PDT 50458 1096 16 the the DT 50458 1096 17 combinations combination NNS 50458 1096 18 they -PRON- PRP 50458 1096 19 afford afford VBP 50458 1096 20 with with IN 50458 1096 21 the the DT 50458 1096 22 various various JJ 50458 1096 23 albuminoid albuminoid NN 50458 1096 24 reagents reagent NNS 50458 1096 25 are be VBP 50458 1096 26 active active JJ 50458 1096 27 , , , 50458 1096 28 despite despite IN 50458 1096 29 their -PRON- PRP$ 50458 1096 30 insolubility insolubility NN 50458 1096 31 . . . 50458 1097 1 According accord VBG 50458 1097 2 to to IN 50458 1097 3 Gautier Gautier NNP 50458 1097 4 , , , 50458 1097 5 they -PRON- PRP 50458 1097 6 are be VBP 50458 1097 7 decomposed decompose VBN 50458 1097 8 by by IN 50458 1097 9 caustic caustic JJ 50458 1097 10 potash potash NN 50458 1097 11 . . . 50458 1098 1 According accord VBG 50458 1098 2 to to IN 50458 1098 3 numerous numerous JJ 50458 1098 4 researches research NNS 50458 1098 5 , , , 50458 1098 6 oxidizers oxidizer VBZ 50458 1098 7 like like IN 50458 1098 8 potassium potassium NN 50458 1098 9 permanganate permanganate NNP 50458 1098 10 , , , 50458 1098 11 the the DT 50458 1098 12 hypochlorites hypochlorite NNS 50458 1098 13 , , , 50458 1098 14 hydrogen hydrogen NN 50458 1098 15 peroxide peroxide NN 50458 1098 16 , , , 50458 1098 17 and and CC 50458 1098 18 gold gold NN 50458 1098 19 chloride chloride NN 50458 1098 20 ( ( -LRB- 50458 1098 21 in in IN 50458 1098 22 1 1 CD 50458 1098 23 % % NN 50458 1098 24 solution solution NN 50458 1098 25 ) ) -RRB- 50458 1098 26 destroy destroy VB 50458 1098 27 the the DT 50458 1098 28 venoms venom NNS 50458 1098 29 ; ; : 50458 1098 30 in in IN 50458 1098 31 certain certain JJ 50458 1098 32 cases case NNS 50458 1098 33 when when WRB 50458 1098 34 immediately immediately RB 50458 1098 35 injected inject VBD 50458 1098 36 hypodermically hypodermically RB 50458 1098 37 in in IN 50458 1098 38 the the DT 50458 1098 39 poisoned poison VBN 50458 1098 40 region region NN 50458 1098 41 , , , 50458 1098 42 these these DT 50458 1098 43 substances substance NNS 50458 1098 44 are be VBP 50458 1098 45 excellent excellent JJ 50458 1098 46 antidotes antidote NNS 50458 1098 47 _ _ NNP 50458 1098 48 in in IN 50458 1098 49 vivo vivo NNP 50458 1098 50 _ _ NNP 50458 1098 51 . . . 50458 1099 1 [ [ -LRB- 50458 1099 2 145 145 CD 50458 1099 3 ] ] -RRB- 50458 1099 4 [ [ -LRB- 50458 1099 5 145 145 CD 50458 1099 6 ] ] -RRB- 50458 1099 7 WINTER WINTER NNP 50458 1099 8 and and CC 50458 1099 9 BLYTH BLYTH NNP 50458 1099 10 : : : 50458 1099 11 _ _ NNP 50458 1099 12 The the DT 50458 1099 13 Analyst Analyst NNP 50458 1099 14 _ _ NNP 50458 1099 15 , , , 50458 1099 16 1877 1877 CD 50458 1099 17 , , , 50458 1099 18 p. p. NN 50458 1099 19 204 204 CD 50458 1099 20 ; ; : 50458 1099 21 LACERDA lacerda NN 50458 1099 22 : : : 50458 1099 23 _ _ NNP 50458 1099 24 Compt Compt NNP 50458 1099 25 . . . 50458 1100 1 rend rend VB 50458 1100 2 . . . 50458 1101 1 de de NNP 50458 1101 2 l'Acad l'Acad NNP 50458 1101 3 . . . 50458 1102 1 des des NNP 50458 1102 2 Sciences Sciences NNPS 50458 1102 3 _ _ NNP 50458 1102 4 , , , 50458 1102 5 XCIII xciii NN 50458 1102 6 , , , 50458 1102 7 p. p. NN 50458 1102 8 466 466 CD 50458 1102 9 ; ; : 50458 1102 10 CALMETTE calmette NN 50458 1102 11 : : : 50458 1102 12 _ _ NNP 50458 1102 13 Annal Annal NNP 50458 1102 14 . . . 50458 1103 1 Instit Instit NNP 50458 1103 2 . . . 50458 1104 1 Pasteur Pasteur NNP 50458 1104 2 _ _ NNP 50458 1104 3 , , , 50458 1104 4 VI VI NNP 50458 1104 5 , , , 50458 1104 6 p. p. NN 50458 1104 7 175 175 CD 50458 1104 8 , , , 50458 1104 9 and and CC 50458 1104 10 VIII VIII NNP 50458 1104 11 , , , 50458 1104 12 p. p. NN 50458 1104 13 278 278 CD 50458 1104 14 . . . 50458 1105 1 We -PRON- PRP 50458 1105 2 shall shall MD 50458 1105 3 not not RB 50458 1105 4 here here RB 50458 1105 5 enter enter VB 50458 1105 6 upon upon IN 50458 1105 7 a a DT 50458 1105 8 detailed detailed JJ 50458 1105 9 study study NN 50458 1105 10 of of IN 50458 1105 11 the the DT 50458 1105 12 toxic toxic JJ 50458 1105 13 albuminoid albuminoid NN 50458 1105 14 principles principle NNS 50458 1105 15 of of IN 50458 1105 16 serpent serpent NN 50458 1105 17 - - HYPH 50458 1105 18 venoms venom NNS 50458 1105 19 ; ; : 50458 1105 20 moreover moreover RB 50458 1105 21 , , , 50458 1105 22 our -PRON- PRP$ 50458 1105 23 knowledge knowledge NN 50458 1105 24 is be VBZ 50458 1105 25 rather rather RB 50458 1105 26 vague vague JJ 50458 1105 27 , , , 50458 1105 28 as as IN 50458 1105 29 it -PRON- PRP 50458 1105 30 is be VBZ 50458 1105 31 , , , 50458 1105 32 on on IN 50458 1105 33 a a DT 50458 1105 34 number number NN 50458 1105 35 of of IN 50458 1105 36 points point NNS 50458 1105 37 . . . 50458 1106 1 It -PRON- PRP 50458 1106 2 will will MD 50458 1106 3 suffice suffice VB 50458 1106 4 us -PRON- PRP 50458 1106 5 to to TO 50458 1106 6 know know VB 50458 1106 7 that that IN 50458 1106 8 , , , 50458 1106 9 taken take VBN 50458 1106 10 altogether altogether RB 50458 1106 11 , , , 50458 1106 12 the the DT 50458 1106 13 active active JJ 50458 1106 14 albuminoids albuminoid NNS 50458 1106 15 of of IN 50458 1106 16 these these DT 50458 1106 17 venoms venom NNS 50458 1106 18 are be VBP 50458 1106 19 numerous numerous JJ 50458 1106 20 , , , 50458 1106 21 and and CC 50458 1106 22 that that IN 50458 1106 23 each each DT 50458 1106 24 venom venom NN 50458 1106 25 has have VBZ 50458 1106 26 its -PRON- PRP$ 50458 1106 27 own own JJ 50458 1106 28 particular particular JJ 50458 1106 29 active active JJ 50458 1106 30 constituents constituent NNS 50458 1106 31 , , , 50458 1106 32 differing differ VBG 50458 1106 33 according accord VBG 50458 1106 34 to to IN 50458 1106 35 the the DT 50458 1106 36 species species NN 50458 1106 37 and and CC 50458 1106 38 variety variety NN 50458 1106 39 of of IN 50458 1106 40 the the DT 50458 1106 41 snake snake NN 50458 1106 42 . . . 50458 1107 1 Each each DT 50458 1107 2 one one NN 50458 1107 3 of of IN 50458 1107 4 these these DT 50458 1107 5 substances substance NNS 50458 1107 6 acts act VBZ 50458 1107 7 more more RBR 50458 1107 8 or or CC 50458 1107 9 less less RBR 50458 1107 10 rapidly rapidly RB 50458 1107 11 , , , 50458 1107 12 and and CC 50458 1107 13 may may MD 50458 1107 14 be be VB 50458 1107 15 associated associate VBN 50458 1107 16 with with IN 50458 1107 17 different different JJ 50458 1107 18 principles principle NNS 50458 1107 19 which which WDT 50458 1107 20 give give VBP 50458 1107 21 rise rise NN 50458 1107 22 to to IN 50458 1107 23 the the DT 50458 1107 24 variability variability NN 50458 1107 25 of of IN 50458 1107 26 the the DT 50458 1107 27 action action NN 50458 1107 28 of of IN 50458 1107 29 these these DT 50458 1107 30 toxic toxic JJ 50458 1107 31 agents agent NNS 50458 1107 32 . . . 50458 1108 1 Among among IN 50458 1108 2 these these DT 50458 1108 3 toxic toxic JJ 50458 1108 4 albuminoids albuminoid NNS 50458 1108 5 , , , 50458 1108 6 the the DT 50458 1108 7 most most RBS 50458 1108 8 virulent virulent NN 50458 1108 9 appear appear VBP 50458 1108 10 to to TO 50458 1108 11 be be VB 50458 1108 12 true true JJ 50458 1108 13 albumins albumin NNS 50458 1108 14 and and CC 50458 1108 15 globulins globulin NNS 50458 1108 16 , , , 50458 1108 17 followed follow VBN 50458 1108 18 by by IN 50458 1108 19 the the DT 50458 1108 20 nucleo nucleo NNP 50458 1108 21 - - HYPH 50458 1108 22 albumins albumin NNS 50458 1108 23 , , , 50458 1108 24 as as IN 50458 1108 25 we -PRON- PRP 50458 1108 26 have have VBP 50458 1108 27 already already RB 50458 1108 28 stated state VBN 50458 1108 29 ; ; : 50458 1108 30 there there EX 50458 1108 31 are be VBP 50458 1108 32 also also RB 50458 1108 33 found find VBN 50458 1108 34 in in IN 50458 1108 35 venoms venom NNS 50458 1108 36 alkaloidal alkaloidal NN 50458 1108 37 bases basis NNS 50458 1108 38 , , , 50458 1108 39 but but CC 50458 1108 40 these these DT 50458 1108 41 principles principle NNS 50458 1108 42 are be VBP 50458 1108 43 present present JJ 50458 1108 44 only only RB 50458 1108 45 in in IN 50458 1108 46 very very RB 50458 1108 47 slight slight JJ 50458 1108 48 quantity quantity NN 50458 1108 49 . . . 50458 1109 1 These these DT 50458 1109 2 bases basis NNS 50458 1109 3 are be VBP 50458 1109 4 but but CC 50458 1109 5 very very RB 50458 1109 6 slightly slightly RB 50458 1109 7 toxic toxic JJ 50458 1109 8 compared compare VBN 50458 1109 9 with with IN 50458 1109 10 the the DT 50458 1109 11 toxins toxin NNS 50458 1109 12 that that WDT 50458 1109 13 accompany accompany VBP 50458 1109 14 them -PRON- PRP 50458 1109 15 . . . 50458 1110 1 = = NFP 50458 1110 2 Natural natural JJ 50458 1110 3 Immunity Immunity NNP 50458 1110 4 towards towards IN 50458 1110 5 Serpent Serpent NNP 50458 1110 6 - - HYPH 50458 1110 7 venoms.=--Certain venoms.=--Certain `` 50458 1110 8 animals animal NNS 50458 1110 9 exhibit exhibit VBP 50458 1110 10 a a DT 50458 1110 11 natural natural JJ 50458 1110 12 immunity immunity NN 50458 1110 13 toward toward IN 50458 1110 14 snake snake NN 50458 1110 15 - - HYPH 50458 1110 16 bites bite NNS 50458 1110 17 ; ; : 50458 1110 18 among among IN 50458 1110 19 them -PRON- PRP 50458 1110 20 are be VBP 50458 1110 21 the the DT 50458 1110 22 snakes snake NNS 50458 1110 23 themselves -PRON- PRP 50458 1110 24 , , , 50458 1110 25 the the DT 50458 1110 26 hog hog NN 50458 1110 27 , , , 50458 1110 28 the the DT 50458 1110 29 hedgehog hedgehog NN 50458 1110 30 , , , 50458 1110 31 and and CC 50458 1110 32 the the DT 50458 1110 33 mongoos mongoo NNS 50458 1110 34 ( ( -LRB- 50458 1110 35 an an DT 50458 1110 36 Egyptian egyptian JJ 50458 1110 37 rat rat NN 50458 1110 38 ) ) -RRB- 50458 1110 39 ; ; : 50458 1110 40 the the DT 50458 1110 41 blood blood NN 50458 1110 42 of of IN 50458 1110 43 these these DT 50458 1110 44 animals animal NNS 50458 1110 45 contains contain VBZ 50458 1110 46 apparently apparently RB 50458 1110 47 an an DT 50458 1110 48 antitoxin antitoxin NN 50458 1110 49 . . . 50458 1111 1 [ [ -LRB- 50458 1111 2 146 146 CD 50458 1111 3 ] ] -RRB- 50458 1111 4 [ [ -LRB- 50458 1111 5 146 146 CD 50458 1111 6 ] ] -RRB- 50458 1111 7 _ _ NNP 50458 1111 8 Compt Compt NNP 50458 1111 9 . . . 50458 1112 1 rend rend VB 50458 1112 2 . . . 50458 1113 1 de de NNP 50458 1113 2 l'Acad l'Acad NNP 50458 1113 3 . . . 50458 1114 1 des des NNP 50458 1114 2 Sciences Sciences NNPS 50458 1114 3 _ _ NNP 50458 1114 4 , , , 50458 1114 5 CXXI CXXI NNP 50458 1114 6 , , , 50458 1114 7 p. p. NN 50458 1114 8 745 745 CD 50458 1114 9 ; ; : 50458 1114 10 JACODOT JACODOT NNP 50458 1114 11 : : : 50458 1114 12 _ _ NNP 50458 1114 13 Arch Arch NNP 50458 1114 14 . . . 50458 1115 1 de de NNP 50458 1115 2 Médecine Médecine NNP 50458 1115 3 Navale Navale NNP 50458 1115 4 _ _ NNP 50458 1115 5 , , , 50458 1115 6 VII VII NNP 50458 1115 7 , , , 50458 1115 8 p. p. NN 50458 1115 9 390 390 CD 50458 1115 10 . . . 50458 1116 1 Fontana[147 fontana[147 CD 50458 1116 2 ] ] -RRB- 50458 1116 3 had have VBD 50458 1116 4 remarked remark VBN 50458 1116 5 that that IN 50458 1116 6 snakes snake NNS 50458 1116 7 were be VBD 50458 1116 8 quite quite RB 50458 1116 9 unaffected unaffected JJ 50458 1116 10 by by IN 50458 1116 11 the the DT 50458 1116 12 bite bite NN 50458 1116 13 of of IN 50458 1116 14 the the DT 50458 1116 15 viper viper NN 50458 1116 16 , , , 50458 1116 17 even even RB 50458 1116 18 when when WRB 50458 1116 19 inoculated inoculate VBN 50458 1116 20 with with IN 50458 1116 21 the the DT 50458 1116 22 venom venom NN 50458 1116 23 hypodermically hypodermically RB 50458 1116 24 . . . 50458 1117 1 Physalix physalix NN 50458 1117 2 and and CC 50458 1117 3 Bertrand[148 Bertrand[148 NNP 50458 1117 4 ] ] -RRB- 50458 1117 5 confirmed confirm VBD 50458 1117 6 these these DT 50458 1117 7 statements statement NNS 50458 1117 8 , , , 50458 1117 9 and and CC 50458 1117 10 showed show VBD 50458 1117 11 that that IN 50458 1117 12 the the DT 50458 1117 13 snake snake NN 50458 1117 14 perfectly perfectly RB 50458 1117 15 resisted resist VBD 50458 1117 16 quantities quantity NNS 50458 1117 17 of of IN 50458 1117 18 viper viper NN 50458 1117 19 - - HYPH 50458 1117 20 venom venom NN 50458 1117 21 capable capable JJ 50458 1117 22 of of IN 50458 1117 23 killing kill VBG 50458 1117 24 at at RB 50458 1117 25 least least RBS 50458 1117 26 20 20 CD 50458 1117 27 guinea guinea NN 50458 1117 28 - - HYPH 50458 1117 29 pigs pig NNS 50458 1117 30 . . . 50458 1118 1 According accord VBG 50458 1118 2 to to IN 50458 1118 3 these these DT 50458 1118 4 scientists scientist NNS 50458 1118 5 , , , 50458 1118 6 this this DT 50458 1118 7 natural natural JJ 50458 1118 8 immunity immunity NN 50458 1118 9 is be VBZ 50458 1118 10 due due JJ 50458 1118 11 to to IN 50458 1118 12 the the DT 50458 1118 13 existence existence NN 50458 1118 14 in in IN 50458 1118 15 the the DT 50458 1118 16 blood blood NN 50458 1118 17 of of IN 50458 1118 18 toxic toxic JJ 50458 1118 19 principles principle NNS 50458 1118 20 analogous analogous JJ 50458 1118 21 to to IN 50458 1118 22 those those DT 50458 1118 23 of of IN 50458 1118 24 viper viper NN 50458 1118 25 's 's POS 50458 1118 26 venom venom NN 50458 1118 27 -- -- : 50458 1118 28 principles principle NNS 50458 1118 29 that that WDT 50458 1118 30 exist exist VBP 50458 1118 31 in in IN 50458 1118 32 the the DT 50458 1118 33 labial labial JJ 50458 1118 34 glands gland NNS 50458 1118 35 of of IN 50458 1118 36 the the DT 50458 1118 37 snake snake NN 50458 1118 38 , , , 50458 1118 39 and and CC 50458 1118 40 pass pass VB 50458 1118 41 into into IN 50458 1118 42 the the DT 50458 1118 43 blood blood NN 50458 1118 44 and and CC 50458 1118 45 the the DT 50458 1118 46 fluids fluid NNS 50458 1118 47 via via IN 50458 1118 48 the the DT 50458 1118 49 internal internal JJ 50458 1118 50 secretions secretion NNS 50458 1118 51 . . . 50458 1119 1 These these DT 50458 1119 2 writers writer NNS 50458 1119 3 , , , 50458 1119 4 and and CC 50458 1119 5 also also RB 50458 1119 6 Calmette Calmette NNP 50458 1119 7 , , , 50458 1119 8 have have VBP 50458 1119 9 shown show VBN 50458 1119 10 that that IN 50458 1119 11 the the DT 50458 1119 12 blood blood NN 50458 1119 13 of of IN 50458 1119 14 venomous venomous JJ 50458 1119 15 serpents serpent NNS 50458 1119 16 becomes become VBZ 50458 1119 17 antitoxic antitoxic NN 50458 1119 18 when when WRB 50458 1119 19 heated heat VBN 50458 1119 20 . . . 50458 1120 1 [ [ -LRB- 50458 1120 2 147 147 CD 50458 1120 3 ] ] -RRB- 50458 1120 4 _ _ NNP 50458 1120 5 Traité Traité NNP 50458 1120 6 sur sur FW 50458 1120 7 le le NNP 50458 1120 8 Venin Venin NNP 50458 1120 9 de de NNP 50458 1120 10 la la NNP 50458 1120 11 Vipère Vipère NNP 50458 1120 12 _ _ NNP 50458 1120 13 , , , 50458 1120 14 Florence Florence NNP 50458 1120 15 , , , 50458 1120 16 1781 1781 CD 50458 1120 17 . . . 50458 1121 1 [ [ -LRB- 50458 1121 2 148 148 CD 50458 1121 3 ] ] -RRB- 50458 1121 4 _ _ NNP 50458 1121 5 Archives Archives NNP 50458 1121 6 de de IN 50458 1121 7 Physiologie Physiologie NNP 50458 1121 8 _ _ NNP 50458 1121 9 , , , 50458 1121 10 1894 1894 CD 50458 1121 11 , , , 50458 1121 12 p. p. NN 50458 1121 13 423 423 CD 50458 1121 14 . . . 50458 1122 1 It -PRON- PRP 50458 1122 2 has have VBZ 50458 1122 3 been be VBN 50458 1122 4 known know VBN 50458 1122 5 for for IN 50458 1122 6 a a DT 50458 1122 7 long long JJ 50458 1122 8 time time NN 50458 1122 9 that that WDT 50458 1122 10 the the DT 50458 1122 11 hedgehog hedgehog NN 50458 1122 12 and and CC 50458 1122 13 the the DT 50458 1122 14 mongoos mongoo NNS 50458 1122 15 eat eat VBP 50458 1122 16 certain certain JJ 50458 1122 17 venomous venomous JJ 50458 1122 18 reptiles reptile NNS 50458 1122 19 , , , 50458 1122 20 and and CC 50458 1122 21 eagerly eagerly RB 50458 1122 22 hunt hunt VB 50458 1122 23 for for IN 50458 1122 24 the the DT 50458 1122 25 vipers viper NNS 50458 1122 26 in in IN 50458 1122 27 particular particular JJ 50458 1122 28 . . . 50458 1123 1 When when WRB 50458 1123 2 the the DT 50458 1123 3 hedgehog hedgehog NN 50458 1123 4 is be VBZ 50458 1123 5 bitten bite VBN 50458 1123 6 , , , 50458 1123 7 which which WDT 50458 1123 8 happens happen VBZ 50458 1123 9 quite quite RB 50458 1123 10 often often RB 50458 1123 11 despite despite IN 50458 1123 12 its -PRON- PRP$ 50458 1123 13 dexterity dexterity NN 50458 1123 14 , , , 50458 1123 15 it -PRON- PRP 50458 1123 16 resists resist VBZ 50458 1123 17 the the DT 50458 1123 18 viper viper NN 50458 1123 19 - - HYPH 50458 1123 20 venom venom NN 50458 1123 21 quite quite RB 50458 1123 22 well well RB 50458 1123 23 . . . 50458 1124 1 Physalix physalix NN 50458 1124 2 and and CC 50458 1124 3 Bertrand[149 bertrand[149 IN 50458 1124 4 ] ] -RRB- 50458 1124 5 have have VBP 50458 1124 6 experimentally experimentally RB 50458 1124 7 demonstrated demonstrate VBN 50458 1124 8 that that IN 50458 1124 9 the the DT 50458 1124 10 hedgehog hedgehog NN 50458 1124 11 withstands withstand VBZ 50458 1124 12 a a DT 50458 1124 13 dose dose NN 50458 1124 14 of of IN 50458 1124 15 viper viper NN 50458 1124 16 - - HYPH 50458 1124 17 venom venom NN 50458 1124 18 capable capable JJ 50458 1124 19 of of IN 50458 1124 20 killing kill VBG 50458 1124 21 at at RB 50458 1124 22 least least RBS 50458 1124 23 40 40 CD 50458 1124 24 guinea guinea NN 50458 1124 25 - - HYPH 50458 1124 26 pigs pig NNS 50458 1124 27 . . . 50458 1125 1 Levin[150 Levin[150 NNP 50458 1125 2 ] ] -RRB- 50458 1125 3 has have VBZ 50458 1125 4 shown show VBN 50458 1125 5 that that IN 50458 1125 6 young young JJ 50458 1125 7 individuals individual NNS 50458 1125 8 are be VBP 50458 1125 9 less less RBR 50458 1125 10 resistant resistant JJ 50458 1125 11 , , , 50458 1125 12 and and CC 50458 1125 13 it -PRON- PRP 50458 1125 14 is be VBZ 50458 1125 15 concluded conclude VBN 50458 1125 16 from from IN 50458 1125 17 this this DT 50458 1125 18 , , , 50458 1125 19 and and CC 50458 1125 20 perhaps perhaps RB 50458 1125 21 incorrectly incorrectly RB 50458 1125 22 so so RB 50458 1125 23 , , , 50458 1125 24 that that IN 50458 1125 25 the the DT 50458 1125 26 immunity immunity NN 50458 1125 27 of of IN 50458 1125 28 the the DT 50458 1125 29 hedgehog hedgehog NN 50458 1125 30 is be VBZ 50458 1125 31 naturally naturally RB 50458 1125 32 acquired acquire VBN 50458 1125 33 , , , 50458 1125 34 rather rather RB 50458 1125 35 than than IN 50458 1125 36 inherent inherent JJ 50458 1125 37 . . . 50458 1126 1 Bertrand Bertrand NNP 50458 1126 2 and and CC 50458 1126 3 Physalix Physalix NNP 50458 1126 4 have have VBP 50458 1126 5 nevertheless nevertheless RB 50458 1126 6 shown show VBN 50458 1126 7 that that IN 50458 1126 8 on on IN 50458 1126 9 heating heat VBG 50458 1126 10 the the DT 50458 1126 11 blood blood NN 50458 1126 12 of of IN 50458 1126 13 the the DT 50458 1126 14 hedgehog hedgehog NN 50458 1126 15 to to IN 50458 1126 16 88 88 CD 50458 1126 17 ° ° , 50458 1126 18 C. C. NNP 50458 1126 19 it -PRON- PRP 50458 1126 20 manifests manifest VBZ 50458 1126 21 an an DT 50458 1126 22 antitoxic antitoxic JJ 50458 1126 23 power power NN 50458 1126 24 toward toward IN 50458 1126 25 serpent serpent NN 50458 1126 26 - - HYPH 50458 1126 27 venom venom NN 50458 1126 28 _ _ NNP 50458 1126 29 in in IN 50458 1126 30 vitro vitro FW 50458 1126 31 _ _ NNP 50458 1126 32 . . . 50458 1127 1 [ [ -LRB- 50458 1127 2 149 149 CD 50458 1127 3 ] ] -RRB- 50458 1127 4 _ _ NNP 50458 1127 5 Bull Bull NNP 50458 1127 6 . . . 50458 1128 1 Muséum Muséum NNP 50458 1128 2 Histoire Histoire NNP 50458 1128 3 Naturelle Naturelle NNP 50458 1128 4 _ _ NNP 50458 1128 5 , , , 50458 1128 6 I -PRON- PRP 50458 1128 7 , , , 50458 1128 8 p. p. NN 50458 1128 9 294 294 CD 50458 1128 10 ; ; : 50458 1128 11 _ _ NNP 50458 1128 12 Compt Compt NNP 50458 1128 13 . . . 50458 1129 1 rend rend VB 50458 1129 2 . . . 50458 1130 1 Soc Soc NNP 50458 1130 2 . . . 50458 1131 1 de de NNP 50458 1131 2 Biol Biol NNP 50458 1131 3 . . . 50458 1131 4 _ _ NNP 50458 1131 5 , , , 50458 1131 6 1899 1899 CD 50458 1131 7 . . . 50458 1131 8 p. p. NN 50458 1131 9 77 77 CD 50458 1131 10 . . . 50458 1132 1 [ [ -LRB- 50458 1132 2 150 150 CD 50458 1132 3 ] ] -RRB- 50458 1132 4 _ _ NNP 50458 1132 5 Deutsche Deutsche NNP 50458 1132 6 med med NNP 50458 1132 7 . . . 50458 1133 1 Woch Woch NNP 50458 1133 2 . . . 50458 1133 3 _ _ NNP 50458 1133 4 , , , 50458 1133 5 1898 1898 CD 50458 1133 6 , , , 50458 1133 7 p. p. NN 50458 1133 8 629 629 CD 50458 1133 9 . . . 50458 1134 1 = = NFP 50458 1134 2 Artificial Artificial NNP 50458 1134 3 Immunity immunity NN 50458 1134 4 toward toward IN 50458 1134 5 Serpent Serpent NNP 50458 1134 6 - - HYPH 50458 1134 7 venom.=--Immunity venom.=--immunity NN 50458 1134 8 may may MD 50458 1134 9 be be VB 50458 1134 10 conferred confer VBN 50458 1134 11 upon upon IN 50458 1134 12 every every DT 50458 1134 13 individual individual NN 50458 1134 14 by by IN 50458 1134 15 utilizing utilize VBG 50458 1134 16 the the DT 50458 1134 17 method method NN 50458 1134 18 of of IN 50458 1134 19 habituation habituation NN 50458 1134 20 . . . 50458 1135 1 This this DT 50458 1135 2 fact fact NN 50458 1135 3 was be VBD 50458 1135 4 simultaneously simultaneously RB 50458 1135 5 elicited elicit VBN 50458 1135 6 by by IN 50458 1135 7 Calmette Calmette NNP 50458 1135 8 , , , 50458 1135 9 Bertrand Bertrand NNP 50458 1135 10 , , , 50458 1135 11 and and CC 50458 1135 12 Physalix Physalix NNP 50458 1135 13 . . . 50458 1136 1 To to TO 50458 1136 2 effect effect VB 50458 1136 3 the the DT 50458 1136 4 immunity immunity NN 50458 1136 5 these these DT 50458 1136 6 scientists scientist NNS 50458 1136 7 prepare prepare VBP 50458 1136 8 an an DT 50458 1136 9 antivenomous antivenomous JJ 50458 1136 10 serum serum NN 50458 1136 11 and and CC 50458 1136 12 inject inject VB 50458 1136 13 it -PRON- PRP 50458 1136 14 into into IN 50458 1136 15 animals animal NNS 50458 1136 16 , , , 50458 1136 17 giving give VBG 50458 1136 18 at at IN 50458 1136 19 first first RB 50458 1136 20 very very RB 50458 1136 21 small small JJ 50458 1136 22 quantities quantity NNS 50458 1136 23 of of IN 50458 1136 24 the the DT 50458 1136 25 diluted diluted JJ 50458 1136 26 venom venom NN 50458 1136 27 , , , 50458 1136 28 and and CC 50458 1136 29 gradually gradually RB 50458 1136 30 increasing increase VBG 50458 1136 31 the the DT 50458 1136 32 doses dose NNS 50458 1136 33 , , , 50458 1136 34 and and CC 50458 1136 35 the the DT 50458 1136 36 periods period NNS 50458 1136 37 intervening intervene VBG 50458 1136 38 between between IN 50458 1136 39 the the DT 50458 1136 40 injections injection NNS 50458 1136 41 . . . 50458 1137 1 At at IN 50458 1137 2 the the DT 50458 1137 3 end end NN 50458 1137 4 of of IN 50458 1137 5 about about RB 50458 1137 6 two two CD 50458 1137 7 months month NNS 50458 1137 8 of of IN 50458 1137 9 this this DT 50458 1137 10 treatment treatment NN 50458 1137 11 , , , 50458 1137 12 the the DT 50458 1137 13 immunity immunity NN 50458 1137 14 has have VBZ 50458 1137 15 reached reach VBN 50458 1137 16 its -PRON- PRP$ 50458 1137 17 maximum maximum NN 50458 1137 18 . . . 50458 1138 1 Certain certain JJ 50458 1138 2 rabbits rabbit NNS 50458 1138 3 , , , 50458 1138 4 thus thus RB 50458 1138 5 slowly slowly RB 50458 1138 6 inoculated inoculate VBN 50458 1138 7 , , , 50458 1138 8 have have VBP 50458 1138 9 been be VBN 50458 1138 10 able able JJ 50458 1138 11 to to TO 50458 1138 12 withstand withstand VB 50458 1138 13 0.04 0.04 CD 50458 1138 14 Gm Gm NNP 50458 1138 15 . . . 50458 1139 1 of of IN 50458 1139 2 the the DT 50458 1139 3 venom venom NN 50458 1139 4 of of IN 50458 1139 5 the the DT 50458 1139 6 naja naja NNS 50458 1139 7 at at IN 50458 1139 8 a a DT 50458 1139 9 single single JJ 50458 1139 10 injection injection NN 50458 1139 11 ; ; : 50458 1139 12 such such JJ 50458 1139 13 rabbits rabbit NNS 50458 1139 14 then then RB 50458 1139 15 yield yield VBP 50458 1139 16 a a DT 50458 1139 17 vaccinal vaccinal JJ 50458 1139 18 serum serum NN 50458 1139 19 . . . 50458 1140 1 [ [ -LRB- 50458 1140 2 151 151 CD 50458 1140 3 ] ] -RRB- 50458 1140 4 [ [ -LRB- 50458 1140 5 151 151 CD 50458 1140 6 ] ] -RRB- 50458 1140 7 _ _ NNP 50458 1140 8 Annal Annal NNP 50458 1140 9 . . . 50458 1141 1 de de NNP 50458 1141 2 l'Instit l'Instit NNP 50458 1141 3 . . . 50458 1142 1 Pasteur Pasteur NNP 50458 1142 2 _ _ NNP 50458 1142 3 , , , 50458 1142 4 1895 1895 CD 50458 1142 5 , , , 50458 1142 6 p. p. NN 50458 1142 7 229 229 CD 50458 1142 8 ; ; : 50458 1142 9 _ _ NNP 50458 1142 10 Compt Compt NNP 50458 1142 11 . . . 50458 1143 1 rend rend VB 50458 1143 2 . . . 50458 1144 1 de de NNP 50458 1144 2 l'Acad l'Acad NNP 50458 1144 3 . . . 50458 1145 1 des des NNP 50458 1145 2 Sciences Sciences NNPS 50458 1145 3 _ _ NNP 50458 1145 4 , , , 50458 1145 5 CXXII CXXII NNP 50458 1145 6 , , , 50458 1145 7 p. p. NN 50458 1145 8 203 203 CD 50458 1145 9 . . . 50458 1146 1 At at IN 50458 1146 2 the the DT 50458 1146 3 Institut Institut NNP 50458 1146 4 Pasteur Pasteur NNP 50458 1146 5 at at IN 50458 1146 6 Lille Lille NNP 50458 1146 7 there there EX 50458 1146 8 is be VBZ 50458 1146 9 prepared prepare VBN 50458 1146 10 in in IN 50458 1146 11 this this DT 50458 1146 12 manner manner NN 50458 1146 13 an an DT 50458 1146 14 antivenomous antivenomous JJ 50458 1146 15 serum serum NN 50458 1146 16 from from IN 50458 1146 17 the the DT 50458 1146 18 horse horse NN 50458 1146 19 ; ; : 50458 1146 20 it -PRON- PRP 50458 1146 21 is be VBZ 50458 1146 22 capable capable JJ 50458 1146 23 of of IN 50458 1146 24 acting act VBG 50458 1146 25 upon upon IN 50458 1146 26 20 20 CD 50458 1146 27 000 000 CD 50458 1146 28 times time NNS 50458 1146 29 its -PRON- PRP$ 50458 1146 30 own own JJ 50458 1146 31 weight weight NN 50458 1146 32 . . . 50458 1147 1 This this DT 50458 1147 2 has have VBZ 50458 1147 3 rendered render VBN 50458 1147 4 great great JJ 50458 1147 5 service service NN 50458 1147 6 in in IN 50458 1147 7 the the DT 50458 1147 8 treatment treatment NN 50458 1147 9 of of IN 50458 1147 10 snake snake NN 50458 1147 11 - - HYPH 50458 1147 12 bites bite NNS 50458 1147 13 , , , 50458 1147 14 particularly particularly RB 50458 1147 15 in in IN 50458 1147 16 hot hot JJ 50458 1147 17 countries country NNS 50458 1147 18 , , , 50458 1147 19 where where WRB 50458 1147 20 the the DT 50458 1147 21 accidents accident NNS 50458 1147 22 are be VBP 50458 1147 23 of of IN 50458 1147 24 daily daily JJ 50458 1147 25 occurrence occurrence NN 50458 1147 26 . . . 50458 1148 1 _ _ NNP 50458 1148 2 In in IN 50458 1148 3 vitro vitro FW 50458 1148 4 _ _ NNP 50458 1148 5 it -PRON- PRP 50458 1148 6 acts act VBZ 50458 1148 7 quite quite RB 50458 1148 8 as as RB 50458 1148 9 well well RB 50458 1148 10 preventively preventively RB 50458 1148 11 as as RB 50458 1148 12 therapeutically therapeutically RB 50458 1148 13 . . . 50458 1149 1 It -PRON- PRP 50458 1149 2 arrests arrest VBZ 50458 1149 3 the the DT 50458 1149 4 effects effect NNS 50458 1149 5 of of IN 50458 1149 6 the the DT 50458 1149 7 naja naja NNP 50458 1149 8 , , , 50458 1149 9 the the DT 50458 1149 10 horned horned JJ 50458 1149 11 ceraste ceraste NN 50458 1149 12 , , , 50458 1149 13 the the DT 50458 1149 14 trigonocephalus trigonocephalus NN 50458 1149 15 , , , 50458 1149 16 the the DT 50458 1149 17 rattlesnake rattlesnake NN 50458 1149 18 , , , 50458 1149 19 and and CC 50458 1149 20 of of IN 50458 1149 21 almost almost RB 50458 1149 22 every every DT 50458 1149 23 one one CD 50458 1149 24 of of IN 50458 1149 25 the the DT 50458 1149 26 venomous venomous JJ 50458 1149 27 serpents serpent NNS 50458 1149 28 known know VBN 50458 1149 29 . . . 50458 1150 1 The the DT 50458 1150 2 relatively relatively RB 50458 1150 3 considerable considerable JJ 50458 1150 4 immunity immunity NN 50458 1150 5 possessed possess VBN 50458 1150 6 by by IN 50458 1150 7 certain certain JJ 50458 1150 8 snake snake NN 50458 1150 9 - - HYPH 50458 1150 10 charmers charmer NNS 50458 1150 11 , , , 50458 1150 12 and and CC 50458 1150 13 which which WDT 50458 1150 14 passes pass VBZ 50458 1150 15 for for IN 50458 1150 16 a a DT 50458 1150 17 magical magical JJ 50458 1150 18 gift gift NN 50458 1150 19 , , , 50458 1150 20 is be VBZ 50458 1150 21 due due JJ 50458 1150 22 to to IN 50458 1150 23 nothing nothing NN 50458 1150 24 else else RB 50458 1150 25 but but CC 50458 1150 26 a a DT 50458 1150 27 natural natural JJ 50458 1150 28 immunity immunity NN 50458 1150 29 , , , 50458 1150 30 acquired acquire VBN 50458 1150 31 perhaps perhaps RB 50458 1150 32 by by IN 50458 1150 33 heredity heredity NN 50458 1150 34 , , , 50458 1150 35 and and CC 50458 1150 36 it -PRON- PRP 50458 1150 37 always always RB 50458 1150 38 appears appear VBZ 50458 1150 39 to to TO 50458 1150 40 follow follow VB 50458 1150 41 as as IN 50458 1150 42 a a DT 50458 1150 43 result result NN 50458 1150 44 of of IN 50458 1150 45 a a DT 50458 1150 46 nonfatal nonfatal JJ 50458 1150 47 snake snake NN 50458 1150 48 - - HYPH 50458 1150 49 bite bite NN 50458 1150 50 . . . 50458 1151 1 = = NFP 50458 1151 2 Venoms Venoms NNP 50458 1151 3 of of IN 50458 1151 4 Batrachians Batrachians NNPS 50458 1151 5 and and CC 50458 1151 6 Saurians.=--We Saurians.=--We NNP 50458 1151 7 observe observe VBP 50458 1151 8 here here RB 50458 1151 9 a a DT 50458 1151 10 fundamental fundamental JJ 50458 1151 11 difference difference NN 50458 1151 12 between between IN 50458 1151 13 these these DT 50458 1151 14 poisons poison NNS 50458 1151 15 and and CC 50458 1151 16 those those DT 50458 1151 17 of of IN 50458 1151 18 snakes snake NNS 50458 1151 19 , , , 50458 1151 20 as as IN 50458 1151 21 we -PRON- PRP 50458 1151 22 shall shall MD 50458 1151 23 see see VB 50458 1151 24 . . . 50458 1152 1 These these DT 50458 1152 2 latter latter JJ 50458 1152 3 , , , 50458 1152 4 in in IN 50458 1152 5 fact fact NN 50458 1152 6 , , , 50458 1152 7 appear appear VB 50458 1152 8 to to TO 50458 1152 9 owe owe VB 50458 1152 10 all all DT 50458 1152 11 their -PRON- PRP$ 50458 1152 12 toxicity toxicity NN 50458 1152 13 to to IN 50458 1152 14 true true JJ 50458 1152 15 toxins toxin NNS 50458 1152 16 which which WDT 50458 1152 17 they -PRON- PRP 50458 1152 18 contain contain VBP 50458 1152 19 , , , 50458 1152 20 while while IN 50458 1152 21 the the DT 50458 1152 22 poisons poison NNS 50458 1152 23 of of IN 50458 1152 24 batrachians batrachian NNS 50458 1152 25 and and CC 50458 1152 26 saurians saurians NNPS 50458 1152 27 are be VBP 50458 1152 28 chiefly chiefly RB 50458 1152 29 composed compose VBN 50458 1152 30 of of IN 50458 1152 31 alkaloidal alkaloidal NN 50458 1152 32 bases basis NNS 50458 1152 33 . . . 50458 1153 1 [ [ -LRB- 50458 1153 2 152 152 CD 50458 1153 3 ] ] -RRB- 50458 1153 4 [ [ -LRB- 50458 1153 5 152 152 CD 50458 1153 6 ] ] -RRB- 50458 1153 7 CLOEZ CLOEZ NNP 50458 1153 8 : : : 50458 1153 9 _ _ NNP 50458 1153 10 Compt Compt NNP 50458 1153 11 . . . 50458 1154 1 rend rend VB 50458 1154 2 . . . 50458 1155 1 de de NNP 50458 1155 2 l'Acad l'Acad NNP 50458 1155 3 . . . 50458 1156 1 des des NNP 50458 1156 2 Sciences Sciences NNPS 50458 1156 3 _ _ NNP 50458 1156 4 , , , 50458 1156 5 XXXIV XXXIV NNP 50458 1156 6 , , , 50458 1156 7 p. p. NN 50458 1156 8 592 592 CD 50458 1156 9 . . . 50458 1157 1 The the DT 50458 1157 2 poison poison NN 50458 1157 3 of of IN 50458 1157 4 toads toad NNS 50458 1157 5 and and CC 50458 1157 6 frogs frog NNS 50458 1157 7 ( ( -LRB- 50458 1157 8 studied study VBN 50458 1157 9 by by IN 50458 1157 10 Faust Faust NNP 50458 1157 11 , , , 50458 1157 12 Bertrand Bertrand NNP 50458 1157 13 , , , 50458 1157 14 and and CC 50458 1157 15 Physalix Physalix NNP 50458 1157 16 ) ) -RRB- 50458 1157 17 is be VBZ 50458 1157 18 chiefly chiefly RB 50458 1157 19 secreted secrete VBN 50458 1157 20 by by IN 50458 1157 21 the the DT 50458 1157 22 glands gland NNS 50458 1157 23 of of IN 50458 1157 24 the the DT 50458 1157 25 subcutaneous subcutaneous JJ 50458 1157 26 tissues tissue NNS 50458 1157 27 of of IN 50458 1157 28 these these DT 50458 1157 29 animals animal NNS 50458 1157 30 ; ; : 50458 1157 31 it -PRON- PRP 50458 1157 32 has have VBZ 50458 1157 33 but but CC 50458 1157 34 a a DT 50458 1157 35 very very RB 50458 1157 36 slight slight JJ 50458 1157 37 action action NN 50458 1157 38 on on IN 50458 1157 39 the the DT 50458 1157 40 unbroken unbroken JJ 50458 1157 41 skin skin NN 50458 1157 42 , , , 50458 1157 43 but but CC 50458 1157 44 it -PRON- PRP 50458 1157 45 rapidly rapidly RB 50458 1157 46 inflames inflame VBZ 50458 1157 47 the the DT 50458 1157 48 nasal nasal NN 50458 1157 49 and and CC 50458 1157 50 buccal buccal JJ 50458 1157 51 conjunctival conjunctival NN 50458 1157 52 mucosa mucosa NNS 50458 1157 53 . . . 50458 1158 1 The the DT 50458 1158 2 poison poison NN 50458 1158 3 is be VBZ 50458 1158 4 a a DT 50458 1158 5 yellowish yellowish JJ 50458 1158 6 liquid liquid NN 50458 1158 7 , , , 50458 1158 8 milky milky NNP 50458 1158 9 and and CC 50458 1158 10 viscid viscid NNP 50458 1158 11 , , , 50458 1158 12 with with IN 50458 1158 13 a a DT 50458 1158 14 waxy waxy NN 50458 1158 15 odor odor NN 50458 1158 16 and and CC 50458 1158 17 an an DT 50458 1158 18 insupportably insupportably RB 50458 1158 19 bitter bitter JJ 50458 1158 20 taste taste NN 50458 1158 21 . . . 50458 1159 1 It -PRON- PRP 50458 1159 2 is be VBZ 50458 1159 3 strongly strongly RB 50458 1159 4 acid acid JJ 50458 1159 5 and and CC 50458 1159 6 caustic caustic JJ 50458 1159 7 . . . 50458 1160 1 When when WRB 50458 1160 2 dried dry VBN 50458 1160 3 , , , 50458 1160 4 the the DT 50458 1160 5 poison poison NN 50458 1160 6 yields yield NNS 50458 1160 7 to to TO 50458 1160 8 ether ether VB 50458 1160 9 a a DT 50458 1160 10 fatty fatty NN 50458 1160 11 matter matter NN 50458 1160 12 which which WDT 50458 1160 13 , , , 50458 1160 14 when when WRB 50458 1160 15 absorbed absorb VBN 50458 1160 16 by by IN 50458 1160 17 an an DT 50458 1160 18 animal animal NN 50458 1160 19 , , , 50458 1160 20 plunges plunge VBZ 50458 1160 21 the the DT 50458 1160 22 latter latter JJ 50458 1160 23 into into IN 50458 1160 24 a a DT 50458 1160 25 coma coma NN 50458 1160 26 that that WDT 50458 1160 27 may may MD 50458 1160 28 end end VB 50458 1160 29 in in IN 50458 1160 30 death death NN 50458 1160 31 . . . 50458 1161 1 The the DT 50458 1161 2 residue residue NN 50458 1161 3 insoluble insoluble JJ 50458 1161 4 in in IN 50458 1161 5 ether ether NN 50458 1161 6 contains contain VBZ 50458 1161 7 the the DT 50458 1161 8 non non JJ 50458 1161 9 - - JJ 50458 1161 10 toxic toxic JJ 50458 1161 11 albuminoids albuminoid NNS 50458 1161 12 , , , 50458 1161 13 and and CC 50458 1161 14 ptomaines ptomaine NNS 50458 1161 15 , , , 50458 1161 16 such such JJ 50458 1161 17 as as IN 50458 1161 18 methylcarbylamine,[153 methylcarbylamine,[153 NNP 50458 1161 19 ] ] -RRB- 50458 1161 20 and and CC 50458 1161 21 isocyanacetic isocyanacetic JJ 50458 1161 22 acid acid NN 50458 1161 23 , , , 50458 1161 24 resulting result VBG 50458 1161 25 from from IN 50458 1161 26 the the DT 50458 1161 27 decomposition decomposition NN 50458 1161 28 of of IN 50458 1161 29 a a DT 50458 1161 30 lecithin lecithin NN 50458 1161 31 that that WDT 50458 1161 32 appears appear VBZ 50458 1161 33 to to TO 50458 1161 34 be be VB 50458 1161 35 soluble soluble JJ 50458 1161 36 in in IN 50458 1161 37 ether ether NN 50458 1161 38 . . . 50458 1162 1 [ [ -LRB- 50458 1162 2 153 153 CD 50458 1162 3 ] ] -RRB- 50458 1162 4 _ _ NNP 50458 1162 5 Ibid Ibid NNP 50458 1162 6 . . . 50458 1162 7 _ _ NNP 50458 1162 8 , , , 50458 1162 9 XCVIII XCVIII NNP 50458 1162 10 , , , 50458 1162 11 p. p. NN 50458 1162 12 538 538 CD 50458 1162 13 . . . 50458 1163 1 To to TO 50458 1163 2 obtain obtain VB 50458 1163 3 this this DT 50458 1163 4 venom venom NN 50458 1163 5 , , , 50458 1163 6 Physalix Physalix NNP 50458 1163 7 and and CC 50458 1163 8 Bertrand[154 Bertrand[154 NNP 50458 1163 9 ] ] -RRB- 50458 1163 10 skin skin NN 50458 1163 11 the the DT 50458 1163 12 toads toad NNS 50458 1163 13 , , , 50458 1163 14 first first RB 50458 1163 15 chloroformed chloroform VBN 50458 1163 16 , , , 50458 1163 17 and and CC 50458 1163 18 dry dry VB 50458 1163 19 the the DT 50458 1163 20 skins skin NNS 50458 1163 21 in in IN 50458 1163 22 a a DT 50458 1163 23 vacuum vacuum NN 50458 1163 24 over over IN 50458 1163 25 sulphuric sulphuric JJ 50458 1163 26 acid acid NN 50458 1163 27 ; ; : 50458 1163 28 the the DT 50458 1163 29 skins skin NNS 50458 1163 30 are be VBP 50458 1163 31 then then RB 50458 1163 32 cleaned clean VBN 50458 1163 33 by by IN 50458 1163 34 treating treat VBG 50458 1163 35 with with IN 50458 1163 36 carbon carbon NN 50458 1163 37 disulphide disulphide NN 50458 1163 38 to to TO 50458 1163 39 remove remove VB 50458 1163 40 fatty fatty NN 50458 1163 41 matters matter NNS 50458 1163 42 , , , 50458 1163 43 and and CC 50458 1163 44 the the DT 50458 1163 45 toxic toxic JJ 50458 1163 46 principles principle NNS 50458 1163 47 removed remove VBN 50458 1163 48 by by IN 50458 1163 49 means mean NNS 50458 1163 50 of of IN 50458 1163 51 95-per 95-per CD 50458 1163 52 cent cent NN 50458 1163 53 . . . 50458 1164 1 alcohol alcohol NN 50458 1164 2 ; ; : 50458 1164 3 the the DT 50458 1164 4 poison poison NN 50458 1164 5 so so RB 50458 1164 6 obtained obtain VBN 50458 1164 7 , , , 50458 1164 8 however however RB 50458 1164 9 , , , 50458 1164 10 is be VBZ 50458 1164 11 impure impure NN 50458 1164 12 . . . 50458 1165 1 A a DT 50458 1165 2 better well JJR 50458 1165 3 procedure procedure NN 50458 1165 4 is be VBZ 50458 1165 5 to to TO 50458 1165 6 express express VB 50458 1165 7 the the DT 50458 1165 8 parotid parotid NN 50458 1165 9 glands gland NNS 50458 1165 10 which which WDT 50458 1165 11 have have VBP 50458 1165 12 been be VBN 50458 1165 13 placed place VBN 50458 1165 14 in in IN 50458 1165 15 distilled distilled JJ 50458 1165 16 water water NN 50458 1165 17 . . . 50458 1166 1 Faust Faust NNP 50458 1166 2 found find VBN 50458 1166 3 in in IN 50458 1166 4 this this DT 50458 1166 5 venom venom NN 50458 1166 6 a a DT 50458 1166 7 principle principle NN 50458 1166 8 which which WDT 50458 1166 9 he -PRON- PRP 50458 1166 10 named name VBD 50458 1166 11 _ _ NNP 50458 1166 12 bufonin bufonin VBD 50458 1166 13 _ _ NNP 50458 1166 14 . . . 50458 1167 1 Physalix Physalix NNP 50458 1167 2 and and CC 50458 1167 3 Bertrand Bertrand NNP 50458 1167 4 isolated isolate VBD 50458 1167 5 from from IN 50458 1167 6 it -PRON- PRP 50458 1167 7 also also RB 50458 1167 8 a a DT 50458 1167 9 resinoid resinoid JJ 50458 1167 10 substance substance NN 50458 1167 11 soluble soluble JJ 50458 1167 12 in in IN 50458 1167 13 alcohol alcohol NN 50458 1167 14 and and CC 50458 1167 15 in in IN 50458 1167 16 a a DT 50458 1167 17 large large JJ 50458 1167 18 excess excess NN 50458 1167 19 of of IN 50458 1167 20 water water NN 50458 1167 21 ; ; : 50458 1167 22 this this DT 50458 1167 23 substance substance NN 50458 1167 24 , , , 50458 1167 25 which which WDT 50458 1167 26 they -PRON- PRP 50458 1167 27 named name VBD 50458 1167 28 _ _ NNP 50458 1167 29 bufotaline bufotaline NN 50458 1167 30 _ _ NNP 50458 1167 31 , , , 50458 1167 32 acts act VBZ 50458 1167 33 upon upon IN 50458 1167 34 the the DT 50458 1167 35 heart heart NN 50458 1167 36 . . . 50458 1168 1 These these DT 50458 1168 2 authors author NNS 50458 1168 3 have have VBP 50458 1168 4 also also RB 50458 1168 5 obtained obtain VBN 50458 1168 6 another another DT 50458 1168 7 substance substance NN 50458 1168 8 which which WDT 50458 1168 9 has have VBZ 50458 1168 10 a a DT 50458 1168 11 paralyzing paralyzing NN 50458 1168 12 action action NN 50458 1168 13 , , , 50458 1168 14 and and CC 50458 1168 15 which which WDT 50458 1168 16 they -PRON- PRP 50458 1168 17 have have VBP 50458 1168 18 named name VBN 50458 1168 19 _ _ NNP 50458 1168 20 bufotenin bufotenin VBN 50458 1168 21 _ _ NNP 50458 1168 22 . . . 50458 1169 1 [ [ -LRB- 50458 1169 2 154 154 CD 50458 1169 3 ] ] -RRB- 50458 1169 4 _ _ NNP 50458 1169 5 Ibid Ibid NNP 50458 1169 6 . . . 50458 1169 7 _ _ NNP 50458 1169 8 , , , 50458 1169 9 CXXVIII CXXVIII NNP 50458 1169 10 , , , 50458 1169 11 pp pp NNP 50458 1169 12 . . . 50458 1170 1 45 45 CD 50458 1170 2 - - SYM 50458 1170 3 48 48 CD 50458 1170 4 . . . 50458 1171 1 The the DT 50458 1171 2 poison poison NN 50458 1171 3 of of IN 50458 1171 4 the the DT 50458 1171 5 common common JJ 50458 1171 6 toad toad NN 50458 1171 7 acts act VBZ 50458 1171 8 as as IN 50458 1171 9 a a DT 50458 1171 10 paralyzant paralyzant NN 50458 1171 11 upon upon IN 50458 1171 12 the the DT 50458 1171 13 heart heart NN 50458 1171 14 and and CC 50458 1171 15 on on IN 50458 1171 16 the the DT 50458 1171 17 spinal spinal JJ 50458 1171 18 marrow[155 marrow[155 NN 50458 1171 19 ] ] -RRB- 50458 1171 20 ; ; : 50458 1171 21 that that DT 50458 1171 22 of of IN 50458 1171 23 the the DT 50458 1171 24 common common JJ 50458 1171 25 frog frog NN 50458 1171 26 possesses possess VBZ 50458 1171 27 similar similar JJ 50458 1171 28 properties property NNS 50458 1171 29 . . . 50458 1172 1 The the DT 50458 1172 2 poison poison NN 50458 1172 3 of of IN 50458 1172 4 the the DT 50458 1172 5 tritons triton NNS 50458 1172 6 is be VBZ 50458 1172 7 quite quite RB 50458 1172 8 analogous analogous JJ 50458 1172 9 to to IN 50458 1172 10 that that DT 50458 1172 11 of of IN 50458 1172 12 the the DT 50458 1172 13 toads toad NNS 50458 1172 14 ; ; : 50458 1172 15 it -PRON- PRP 50458 1172 16 contains contain VBZ 50458 1172 17 a a DT 50458 1172 18 lecithin lecithin JJ 50458 1172 19 hydrolyzable hydrolyzable JJ 50458 1172 20 by by IN 50458 1172 21 water water NN 50458 1172 22 with with IN 50458 1172 23 the the DT 50458 1172 24 formation formation NN 50458 1172 25 of of IN 50458 1172 26 alanin alanin NN 50458 1172 27 , , , 50458 1172 28 formic formic NN 50458 1172 29 acid acid NN 50458 1172 30 , , , 50458 1172 31 and and CC 50458 1172 32 alpha alpha NN 50458 1172 33 - - HYPH 50458 1172 34 isocyanopropionic isocyanopropionic JJ 50458 1172 35 acid acid NN 50458 1172 36 . . . 50458 1173 1 [ [ -LRB- 50458 1173 2 155 155 CD 50458 1173 3 ] ] -RRB- 50458 1173 4 P. P. NNP 50458 1173 5 BERT BERT NNP 50458 1173 6 : : : 50458 1173 7 _ _ NNP 50458 1173 8 Compt Compt NNP 50458 1173 9 . . . 50458 1174 1 rend rend VB 50458 1174 2 . . . 50458 1175 1 de de NNP 50458 1175 2 la la NNP 50458 1175 3 Soc Soc NNP 50458 1175 4 . . . 50458 1176 1 de de NNP 50458 1176 2 Biologie Biologie NNP 50458 1176 3 _ _ NNP 50458 1176 4 , , , 50458 1176 5 1885 1885 CD 50458 1176 6 , , , 50458 1176 7 p. p. NN 50458 1176 8 524 524 CD 50458 1176 9 . . . 50458 1177 1 Zalnosky[156 Zalnosky[156 NNP 50458 1177 2 ] ] -RRB- 50458 1177 3 isolated isolate VBN 50458 1177 4 from from IN 50458 1177 5 the the DT 50458 1177 6 glands gland NNS 50458 1177 7 of of IN 50458 1177 8 the the DT 50458 1177 9 skin skin NN 50458 1177 10 of of IN 50458 1177 11 the the DT 50458 1177 12 salamander salamander JJ 50458 1177 13 a a DT 50458 1177 14 white white JJ 50458 1177 15 , , , 50458 1177 16 thick thick JJ 50458 1177 17 , , , 50458 1177 18 bitter bitter JJ 50458 1177 19 and and CC 50458 1177 20 alkaline alkaline JJ 50458 1177 21 liquid liquid JJ 50458 1177 22 poison poison NN 50458 1177 23 , , , 50458 1177 24 containing contain VBG 50458 1177 25 a a DT 50458 1177 26 highly highly RB 50458 1177 27 poisonous poisonous JJ 50458 1177 28 alkaloid alkaloid NN 50458 1177 29 , , , 50458 1177 30 _ _ NNP 50458 1177 31 salamandrine salamandrine NNP 50458 1177 32 _ _ NNP 50458 1177 33 , , , 50458 1177 34 or or CC 50458 1177 35 _ _ NNP 50458 1177 36 samandarine samandarine NN 50458 1177 37 _ _ NNP 50458 1177 38 , , , 50458 1177 39 which which WDT 50458 1177 40 acts act VBZ 50458 1177 41 on on IN 50458 1177 42 the the DT 50458 1177 43 brain brain NN 50458 1177 44 , , , 50458 1177 45 the the DT 50458 1177 46 medulla medulla NN 50458 1177 47 , , , 50458 1177 48 and and CC 50458 1177 49 the the DT 50458 1177 50 spinal spinal JJ 50458 1177 51 cord cord NN 50458 1177 52 , , , 50458 1177 53 and and CC 50458 1177 54 which which WDT 50458 1177 55 has have VBZ 50458 1177 56 the the DT 50458 1177 57 formula formula NN 50458 1177 58 C{54}H{60}N{2}O{5 c{54}h{60}n{2}o{5 NN 50458 1177 59 } } -RRB- 50458 1177 60 ; ; : 50458 1177 61 it -PRON- PRP 50458 1177 62 is be VBZ 50458 1177 63 a a DT 50458 1177 64 strong strong JJ 50458 1177 65 base base NN 50458 1177 66 and and CC 50458 1177 67 yields yield NNS 50458 1177 68 crystallizable crystallizable JJ 50458 1177 69 salts salt NNS 50458 1177 70 . . . 50458 1178 1 [ [ -LRB- 50458 1178 2 156 156 CD 50458 1178 3 ] ] -RRB- 50458 1178 4 _ _ NNP 50458 1178 5 Bull Bull NNP 50458 1178 6 . . . 50458 1179 1 Soc Soc NNP 50458 1179 2 . . . 50458 1180 1 Chim Chim NNP 50458 1180 2 . . . 50458 1180 3 _ _ NNP 50458 1180 4 [ [ -LRB- 50458 1180 5 2 2 CD 50458 1180 6 ] ] -RRB- 50458 1180 7 , , , 50458 1180 8 VI VI NNP 50458 1180 9 , , , 50458 1180 10 p. p. NN 50458 1180 11 344 344 CD 50458 1180 12 . . . 50458 1181 1 = = NFP 50458 1181 2 Fish fish NN 50458 1181 3 - - HYPH 50458 1181 4 poisons.=[157]--Very poisons.=[157]--very NN 50458 1181 5 little little JJ 50458 1181 6 accurate accurate JJ 50458 1181 7 knowledge knowledge NN 50458 1181 8 is be VBZ 50458 1181 9 extant extant JJ 50458 1181 10 regarding regard VBG 50458 1181 11 these these DT 50458 1181 12 . . . 50458 1182 1 Many many JJ 50458 1182 2 fish fish NN 50458 1182 3 are be VBP 50458 1182 4 poisonous poisonous JJ 50458 1182 5 , , , 50458 1182 6 and and CC 50458 1182 7 among among IN 50458 1182 8 them -PRON- PRP 50458 1182 9 are be VBP 50458 1182 10 the the DT 50458 1182 11 synanceia synanceia NNS 50458 1182 12 , , , 50458 1182 13 found find VBN 50458 1182 14 in in IN 50458 1182 15 the the DT 50458 1182 16 Indian Indian NNP 50458 1182 17 Ocean Ocean NNP 50458 1182 18 between between IN 50458 1182 19 the the DT 50458 1182 20 Netherland Netherland NNP 50458 1182 21 Isles Isles NNPS 50458 1182 22 and and CC 50458 1182 23 New New NNP 50458 1182 24 Caledonia Caledonia NNP 50458 1182 25 ; ; : 50458 1182 26 considerable considerable JJ 50458 1182 27 numbers number NNS 50458 1182 28 are be VBP 50458 1182 29 found find VBN 50458 1182 30 in in IN 50458 1182 31 the the DT 50458 1182 32 neighborhood neighborhood NN 50458 1182 33 of of IN 50458 1182 34 the the DT 50458 1182 35 latter latter JJ 50458 1182 36 locality locality NN 50458 1182 37 . . . 50458 1183 1 These these DT 50458 1183 2 fish fish NNS 50458 1183 3 are be VBP 50458 1183 4 provided provide VBN 50458 1183 5 with with IN 50458 1183 6 spiny spiny JJ 50458 1183 7 rays ray NNS 50458 1183 8 which which WDT 50458 1183 9 are be VBP 50458 1183 10 in in IN 50458 1183 11 direct direct JJ 50458 1183 12 communication communication NN 50458 1183 13 with with IN 50458 1183 14 a a DT 50458 1183 15 poisonous poisonous JJ 50458 1183 16 system system NN 50458 1183 17 having have VBG 50458 1183 18 its -PRON- PRP$ 50458 1183 19 seat seat NN 50458 1183 20 in in IN 50458 1183 21 the the DT 50458 1183 22 dorsal dorsal NN 50458 1183 23 fin fin NN 50458 1183 24 . . . 50458 1184 1 The the DT 50458 1184 2 prick prick NN 50458 1184 3 of of IN 50458 1184 4 one one CD 50458 1184 5 of of IN 50458 1184 6 the the DT 50458 1184 7 spiny spiny JJ 50458 1184 8 rays ray NNS 50458 1184 9 of of IN 50458 1184 10 this this DT 50458 1184 11 fish fish NN 50458 1184 12 may may MD 50458 1184 13 under under IN 50458 1184 14 certain certain JJ 50458 1184 15 circumstances circumstance NNS 50458 1184 16 result result VBP 50458 1184 17 fatally fatally RB 50458 1184 18 , , , 50458 1184 19 and and CC 50458 1184 20 in in IN 50458 1184 21 every every DT 50458 1184 22 case case NN 50458 1184 23 it -PRON- PRP 50458 1184 24 causes cause VBZ 50458 1184 25 a a DT 50458 1184 26 rapid rapid JJ 50458 1184 27 and and CC 50458 1184 28 painful painful JJ 50458 1184 29 gangrene gangrene NN 50458 1184 30 . . . 50458 1185 1 [ [ -LRB- 50458 1185 2 157 157 CD 50458 1185 3 ] ] -RRB- 50458 1185 4 BOFFORD BOFFORD NNP 50458 1185 5 : : : 50458 1185 6 _ _ NNP 50458 1185 7 Thèse Thèse NNP 50458 1185 8 de de NNP 50458 1185 9 doctorat doctorat FW 50458 1185 10 en en FW 50458 1185 11 Médecine Médecine NNP 50458 1185 12 -- -- : 50458 1185 13 Les Les NNP 50458 1185 14 Poissons Poissons NNPS 50458 1185 15 venimeux venimeux JJ 50458 1185 16 _ _ NNP 50458 1185 17 , , , 50458 1185 18 Paris Paris NNP 50458 1185 19 , , , 50458 1185 20 1889 1889 CD 50458 1185 21 ; ; : 50458 1185 22 O. O. NNP 50458 1185 23 ARCOS ARCOS NNP 50458 1185 24 : : : 50458 1185 25 _ _ NNP 50458 1185 26 Thèse Thèse NNP 50458 1185 27 de de NNP 50458 1185 28 doctorat doctorat NN 50458 1185 29 -- -- . 50458 1185 30 Essais essais JJ 50458 1185 31 sur sur FW 50458 1185 32 les les NNP 50458 1185 33 accidents accident NNS 50458 1185 34 causés causé VBZ 50458 1185 35 par par NNP 50458 1185 36 les les NNP 50458 1185 37 poissons poisson NNS 50458 1185 38 venimeux venimeux JJ 50458 1185 39 _ _ NNP 50458 1185 40 , , , 50458 1185 41 Paris Paris NNP 50458 1185 42 , , , 50458 1185 43 1887 1887 CD 50458 1185 44 . . . 50458 1186 1 From from IN 50458 1186 2 the the DT 50458 1186 3 reservoir reservoir NN 50458 1186 4 the the DT 50458 1186 5 poison poison NN 50458 1186 6 is be VBZ 50458 1186 7 conducted conduct VBN 50458 1186 8 to to IN 50458 1186 9 the the DT 50458 1186 10 sharp sharp JJ 50458 1186 11 extremity extremity NN 50458 1186 12 of of IN 50458 1186 13 the the DT 50458 1186 14 spines spine NNS 50458 1186 15 by by IN 50458 1186 16 a a DT 50458 1186 17 deep deep JJ 50458 1186 18 channel channel NN 50458 1186 19 with with IN 50458 1186 20 which which WDT 50458 1186 21 each each DT 50458 1186 22 spiny spiny NNP 50458 1186 23 ray ray NNP 50458 1186 24 is be VBZ 50458 1186 25 provided provide VBN 50458 1186 26 ; ; : 50458 1186 27 the the DT 50458 1186 28 animal animal NN 50458 1186 29 has have VBZ 50458 1186 30 26 26 CD 50458 1186 31 poison poison NN 50458 1186 32 - - HYPH 50458 1186 33 sacs sacs NN 50458 1186 34 , , , 50458 1186 35 two two CD 50458 1186 36 for for IN 50458 1186 37 each each DT 50458 1186 38 ray ray NN 50458 1186 39 , , , 50458 1186 40 and and CC 50458 1186 41 the the DT 50458 1186 42 sacs sac NNS 50458 1186 43 burst burst VBD 50458 1186 44 when when WRB 50458 1186 45 the the DT 50458 1186 46 corresponding corresponding JJ 50458 1186 47 sting sting NN 50458 1186 48 is be VBZ 50458 1186 49 in in IN 50458 1186 50 any any DT 50458 1186 51 manner manner NN 50458 1186 52 compressed compress VBN 50458 1186 53 . . . 50458 1187 1 The the DT 50458 1187 2 poison poison NN 50458 1187 3 is be VBZ 50458 1187 4 an an DT 50458 1187 5 odorless odorless JJ 50458 1187 6 liquid liquid NN 50458 1187 7 having have VBG 50458 1187 8 a a DT 50458 1187 9 slight slight JJ 50458 1187 10 styptic styptic JJ 50458 1187 11 or or CC 50458 1187 12 acidulous acidulous JJ 50458 1187 13 taste taste NN 50458 1187 14 , , , 50458 1187 15 and and CC 50458 1187 16 exhibiting exhibit VBG 50458 1187 17 a a DT 50458 1187 18 bluish bluish JJ 50458 1187 19 fluorescence fluorescence NN 50458 1187 20 ; ; : 50458 1187 21 it -PRON- PRP 50458 1187 22 rapidly rapidly RB 50458 1187 23 becomes become VBZ 50458 1187 24 turbid turbid RB 50458 1187 25 . . . 50458 1188 1 The the DT 50458 1188 2 weevers weever NNS 50458 1188 3 , , , 50458 1188 4 which which WDT 50458 1188 5 are be VBP 50458 1188 6 numerous numerous JJ 50458 1188 7 on on IN 50458 1188 8 the the DT 50458 1188 9 shores shore NNS 50458 1188 10 of of IN 50458 1188 11 the the DT 50458 1188 12 Mediterranean Mediterranean NNP 50458 1188 13 Sea Sea NNP 50458 1188 14 , , , 50458 1188 15 and and CC 50458 1188 16 which which WDT 50458 1188 17 are be VBP 50458 1188 18 also also RB 50458 1188 19 met meet VBN 50458 1188 20 with with IN 50458 1188 21 in in IN 50458 1188 22 the the DT 50458 1188 23 northeastern northeastern JJ 50458 1188 24 portion portion NN 50458 1188 25 of of IN 50458 1188 26 the the DT 50458 1188 27 Atlantic Atlantic NNP 50458 1188 28 Ocean Ocean NNP 50458 1188 29 , , , 50458 1188 30 are be VBP 50458 1188 31 likewise likewise RB 50458 1188 32 very very RB 50458 1188 33 dangerous dangerous JJ 50458 1188 34 , , , 50458 1188 35 which which WDT 50458 1188 36 explains explain VBZ 50458 1188 37 their -PRON- PRP$ 50458 1188 38 popular popular JJ 50458 1188 39 names name NNS 50458 1188 40 " " '' 50458 1188 41 viper viper NN 50458 1188 42 - - HYPH 50458 1188 43 weever weever NN 50458 1188 44 , , , 50458 1188 45 " " '' 50458 1188 46 " " `` 50458 1188 47 spiderweever spiderweever NNP 50458 1188 48 , , , 50458 1188 49 " " '' 50458 1188 50 etc etc FW 50458 1188 51 . . . 50458 1189 1 These these DT 50458 1189 2 fish fish NNS 50458 1189 3 are be VBP 50458 1189 4 provided provide VBN 50458 1189 5 with with IN 50458 1189 6 a a DT 50458 1189 7 double double JJ 50458 1189 8 set set NN 50458 1189 9 of of IN 50458 1189 10 poisonous poisonous JJ 50458 1189 11 apparatus apparatus NN 50458 1189 12 , , , 50458 1189 13 the the DT 50458 1189 14 one one CD 50458 1189 15 opercular opercular JJ 50458 1189 16 , , , 50458 1189 17 which which WDT 50458 1189 18 is be VBZ 50458 1189 19 the the DT 50458 1189 20 more more RBR 50458 1189 21 dangerous dangerous JJ 50458 1189 22 , , , 50458 1189 23 and and CC 50458 1189 24 the the DT 50458 1189 25 other other JJ 50458 1189 26 dorsal dorsal NN 50458 1189 27 . . . 50458 1190 1 The the DT 50458 1190 2 opercular opercular JJ 50458 1190 3 spine spine NN 50458 1190 4 has have VBZ 50458 1190 5 a a DT 50458 1190 6 double double JJ 50458 1190 7 channel channel NN 50458 1190 8 in in IN 50458 1190 9 connection connection NN 50458 1190 10 with with IN 50458 1190 11 a a DT 50458 1190 12 conical conical JJ 50458 1190 13 cavity cavity NN 50458 1190 14 hollowed hollow VBD 50458 1190 15 out out RP 50458 1190 16 in in IN 50458 1190 17 the the DT 50458 1190 18 base base NN 50458 1190 19 of of IN 50458 1190 20 the the DT 50458 1190 21 opercular opercular JJ 50458 1190 22 bone bone NN 50458 1190 23 . . . 50458 1191 1 The the DT 50458 1191 2 bottom bottom NN 50458 1191 3 of of IN 50458 1191 4 this this DT 50458 1191 5 cavity cavity NN 50458 1191 6 is be VBZ 50458 1191 7 provided provide VBN 50458 1191 8 with with IN 50458 1191 9 special special JJ 50458 1191 10 cells cell NNS 50458 1191 11 which which WDT 50458 1191 12 secrete secrete VBP 50458 1191 13 the the DT 50458 1191 14 poison poison NN 50458 1191 15 . . . 50458 1192 1 The the DT 50458 1192 2 dorsal dorsal NN 50458 1192 3 glands gland NNS 50458 1192 4 have have VBP 50458 1192 5 a a DT 50458 1192 6 similar similar JJ 50458 1192 7 structure structure NN 50458 1192 8 . . . 50458 1193 1 The the DT 50458 1193 2 poison poison NN 50458 1193 3 of of IN 50458 1193 4 the the DT 50458 1193 5 weever weever NN 50458 1193 6 is be VBZ 50458 1193 7 a a DT 50458 1193 8 liquid liquid JJ 50458 1193 9 , , , 50458 1193 10 limpid limpid JJ 50458 1193 11 when when WRB 50458 1193 12 the the DT 50458 1193 13 fish fish NN 50458 1193 14 is be VBZ 50458 1193 15 alive alive JJ 50458 1193 16 , , , 50458 1193 17 and and CC 50458 1193 18 turbid turbid RB 50458 1193 19 when when WRB 50458 1193 20 dead dead JJ 50458 1193 21 ; ; : 50458 1193 22 it -PRON- PRP 50458 1193 23 has have VBZ 50458 1193 24 a a DT 50458 1193 25 slight slight JJ 50458 1193 26 bluish bluish JJ 50458 1193 27 fluorescence fluorescence NN 50458 1193 28 , , , 50458 1193 29 is be VBZ 50458 1193 30 neutral neutral JJ 50458 1193 31 in in IN 50458 1193 32 reaction reaction NN 50458 1193 33 , , , 50458 1193 34 and and CC 50458 1193 35 is be VBZ 50458 1193 36 coagulated coagulate VBN 50458 1193 37 by by IN 50458 1193 38 acids acid NNS 50458 1193 39 and and CC 50458 1193 40 bases basis NNS 50458 1193 41 . . . 50458 1194 1 It -PRON- PRP 50458 1194 2 acts act VBZ 50458 1194 3 as as IN 50458 1194 4 a a DT 50458 1194 5 paralyzant paralyzant NN 50458 1194 6 , , , 50458 1194 7 its -PRON- PRP$ 50458 1194 8 action action NN 50458 1194 9 being be VBG 50458 1194 10 exerted exert VBN 50458 1194 11 on on IN 50458 1194 12 the the DT 50458 1194 13 medulla medulla NN 50458 1194 14 and and CC 50458 1194 15 spinal spinal JJ 50458 1194 16 cord cord NN 50458 1194 17 ; ; : 50458 1194 18 it -PRON- PRP 50458 1194 19 retards retard VBZ 50458 1194 20 the the DT 50458 1194 21 heart heart NN 50458 1194 22 's 's POS 50458 1194 23 action action NN 50458 1194 24 . . . 50458 1195 1 These these DT 50458 1195 2 examples example NNS 50458 1195 3 will will MD 50458 1195 4 suffice suffice VB 50458 1195 5 ; ; : 50458 1195 6 and and CC 50458 1195 7 we -PRON- PRP 50458 1195 8 will will MD 50458 1195 9 not not RB 50458 1195 10 dilate dilate VB 50458 1195 11 further far RBR 50458 1195 12 on on IN 50458 1195 13 this this DT 50458 1195 14 subject subject NN 50458 1195 15 , , , 50458 1195 16 because because IN 50458 1195 17 , , , 50458 1195 18 as as IN 50458 1195 19 already already RB 50458 1195 20 stated state VBN 50458 1195 21 , , , 50458 1195 22 but but CC 50458 1195 23 little little JJ 50458 1195 24 is be VBZ 50458 1195 25 accurately accurately RB 50458 1195 26 known know VBN 50458 1195 27 regarding regard VBG 50458 1195 28 the the DT 50458 1195 29 subject subject NN 50458 1195 30 , , , 50458 1195 31 and and CC 50458 1195 32 what what WP 50458 1195 33 is be VBZ 50458 1195 34 known know VBN 50458 1195 35 may may MD 50458 1195 36 be be VB 50458 1195 37 summed sum VBN 50458 1195 38 up up RP 50458 1195 39 as as IN 50458 1195 40 follows follow VBZ 50458 1195 41 : : : 50458 1195 42 Fish fish NN 50458 1195 43 - - HYPH 50458 1195 44 poisons poison NNS 50458 1195 45 always always RB 50458 1195 46 give give VBP 50458 1195 47 rise rise NN 50458 1195 48 to to IN 50458 1195 49 an an DT 50458 1195 50 intense intense JJ 50458 1195 51 pain pain NN 50458 1195 52 , , , 50458 1195 53 frequently frequently RB 50458 1195 54 with with IN 50458 1195 55 motor motor NN 50458 1195 56 paralysis paralysis NN 50458 1195 57 , , , 50458 1195 58 followed follow VBN 50458 1195 59 by by IN 50458 1195 60 paralysis paralysis NN 50458 1195 61 of of IN 50458 1195 62 sensation sensation NN 50458 1195 63 ; ; : 50458 1195 64 they -PRON- PRP 50458 1195 65 affect affect VBP 50458 1195 66 the the DT 50458 1195 67 heart heart NN 50458 1195 68 , , , 50458 1195 69 arresting arrest VBG 50458 1195 70 it -PRON- PRP 50458 1195 71 in in IN 50458 1195 72 diastole diastole NNP 50458 1195 73 ; ; : 50458 1195 74 and and CC 50458 1195 75 they -PRON- PRP 50458 1195 76 are be VBP 50458 1195 77 more more RBR 50458 1195 78 dangerous dangerous JJ 50458 1195 79 to to TO 50458 1195 80 fish fish VB 50458 1195 81 and and CC 50458 1195 82 cold cold JJ 50458 1195 83 - - HYPH 50458 1195 84 blooded blooded JJ 50458 1195 85 animals animal NNS 50458 1195 86 than than IN 50458 1195 87 to to IN 50458 1195 88 mammifers mammifer NNS 50458 1195 89 . . . 50458 1196 1 = = NFP 50458 1196 2 Poisons poison NNS 50458 1196 3 of of IN 50458 1196 4 the the DT 50458 1196 5 Hymenoptera.=[158]--The Hymenoptera.=[158]--The NNP 50458 1196 6 poison poison NN 50458 1196 7 system system NN 50458 1196 8 of of IN 50458 1196 9 the the DT 50458 1196 10 bee bee NN 50458 1196 11 , , , 50458 1196 12 and and CC 50458 1196 13 of of IN 50458 1196 14 such such JJ 50458 1196 15 insects insect NNS 50458 1196 16 as as IN 50458 1196 17 the the DT 50458 1196 18 wasps wasp NNS 50458 1196 19 , , , 50458 1196 20 bumblebees bumblebee NNS 50458 1196 21 , , , 50458 1196 22 etc etc FW 50458 1196 23 . . . 50458 1196 24 , , , 50458 1196 25 is be VBZ 50458 1196 26 known know VBN 50458 1196 27 to to TO 50458 1196 28 consist consist VB 50458 1196 29 of of IN 50458 1196 30 a a DT 50458 1196 31 hollow hollow JJ 50458 1196 32 sting ste VBG 50458 1196 33 consisting consist VBG 50458 1196 34 of of IN 50458 1196 35 two two CD 50458 1196 36 sharp sharp JJ 50458 1196 37 needles needle NNS 50458 1196 38 communicating communicate VBG 50458 1196 39 with with IN 50458 1196 40 two two CD 50458 1196 41 poison poison NN 50458 1196 42 - - HYPH 50458 1196 43 bearing bear VBG 50458 1196 44 glands gland NNS 50458 1196 45 , , , 50458 1196 46 and and CC 50458 1196 47 forming form VBG 50458 1196 48 a a DT 50458 1196 49 flexible flexible JJ 50458 1196 50 tube tube NN 50458 1196 51 . . . 50458 1197 1 One one CD 50458 1197 2 of of IN 50458 1197 3 these these DT 50458 1197 4 glands gland NNS 50458 1197 5 secretes secrete VBZ 50458 1197 6 an an DT 50458 1197 7 acid acid JJ 50458 1197 8 liquid liquid NN 50458 1197 9 ( ( -LRB- 50458 1197 10 formic formic JJ 50458 1197 11 acid acid NN 50458 1197 12 ) ) -RRB- 50458 1197 13 ; ; : 50458 1197 14 the the DT 50458 1197 15 other other JJ 50458 1197 16 secretes secrete VBZ 50458 1197 17 an an DT 50458 1197 18 alkaline alkaline NN 50458 1197 19 fluid fluid NN 50458 1197 20 . . . 50458 1198 1 [ [ -LRB- 50458 1198 2 158 158 CD 50458 1198 3 ] ] -RRB- 50458 1198 4 PHILOUZE PHILOUZE NNP 50458 1198 5 : : : 50458 1198 6 Venin Venin NNP 50458 1198 7 des des NNP 50458 1198 8 Abeilles Abeilles NNP 50458 1198 9 . . . 50458 1199 1 _ _ NNP 50458 1199 2 Annales Annales NNP 50458 1199 3 de de IN 50458 1199 4 la la NNP 50458 1199 5 Société Société NNP 50458 1199 6 Linn Linn NNP 50458 1199 7 . . . 50458 1200 1 du du NNP 50458 1200 2 Maine Maine NNP 50458 1200 3 - - HYPH 50458 1200 4 et et FW 50458 1200 5 - - HYPH 50458 1200 6 Loire Loire NNP 50458 1200 7 _ _ NNP 50458 1200 8 , , , 50458 1200 9 IV IV NNP 50458 1200 10 . . . 50458 1201 1 The the DT 50458 1201 2 action action NN 50458 1201 3 of of IN 50458 1201 4 the the DT 50458 1201 5 bee bee NNP 50458 1201 6 - - HYPH 50458 1201 7 poison poison NN 50458 1201 8 is be VBZ 50458 1201 9 very very RB 50458 1201 10 often often RB 50458 1201 11 benign benign JJ 50458 1201 12 , , , 50458 1201 13 but but CC 50458 1201 14 there there EX 50458 1201 15 have have VBP 50458 1201 16 been be VBN 50458 1201 17 cases case NNS 50458 1201 18 where where WRB 50458 1201 19 death death NN 50458 1201 20 followed follow VBD 50458 1201 21 the the DT 50458 1201 22 infliction infliction NN 50458 1201 23 of of IN 50458 1201 24 numerous numerous JJ 50458 1201 25 stings sting NNS 50458 1201 26 . . . 50458 1202 1 Our -PRON- PRP$ 50458 1202 2 information information NN 50458 1202 3 regarding regard VBG 50458 1202 4 the the DT 50458 1202 5 poison poison NN 50458 1202 6 of of IN 50458 1202 7 the the DT 50458 1202 8 cantharides cantharide NNS 50458 1202 9 and and CC 50458 1202 10 flies fly NNS 50458 1202 11 is be VBZ 50458 1202 12 very very RB 50458 1202 13 vague[159 vague[159 JJ 50458 1202 14 ] ] -RRB- 50458 1202 15 ; ; : 50458 1202 16 the the DT 50458 1202 17 same same JJ 50458 1202 18 is be VBZ 50458 1202 19 true true JJ 50458 1202 20 of of IN 50458 1202 21 the the DT 50458 1202 22 poisons poison NNS 50458 1202 23 of of IN 50458 1202 24 various various JJ 50458 1202 25 arachnids arachnid NNS 50458 1202 26 , , , 50458 1202 27 acarides acaride NNS 50458 1202 28 , , , 50458 1202 29 and and CC 50458 1202 30 myriapoda myriapoda NNP 50458 1202 31 . . . 50458 1203 1 So so RB 50458 1203 2 far far RB 50458 1203 3 as as IN 50458 1203 4 spiders spider NNS 50458 1203 5 are be VBP 50458 1203 6 concerned concern VBN 50458 1203 7 , , , 50458 1203 8 it -PRON- PRP 50458 1203 9 is be VBZ 50458 1203 10 known know VBN 50458 1203 11 that that IN 50458 1203 12 their -PRON- PRP$ 50458 1203 13 poison poison NN 50458 1203 14 is be VBZ 50458 1203 15 an an DT 50458 1203 16 oily oily JJ 50458 1203 17 liquid liquid NN 50458 1203 18 having have VBG 50458 1203 19 an an DT 50458 1203 20 acid acid JJ 50458 1203 21 and and CC 50458 1203 22 bitter bitter JJ 50458 1203 23 taste taste NN 50458 1203 24 , , , 50458 1203 25 and and CC 50458 1203 26 containing contain VBG 50458 1203 27 a a DT 50458 1203 28 toxalbumin toxalbumin NN 50458 1203 29 derived derive VBN 50458 1203 30 from from IN 50458 1203 31 the the DT 50458 1203 32 skin skin NN 50458 1203 33 of of IN 50458 1203 34 the the DT 50458 1203 35 insect insect NN 50458 1203 36 . . . 50458 1204 1 The the DT 50458 1204 2 bite bite NN 50458 1204 3 of of IN 50458 1204 4 the the DT 50458 1204 5 ordinary ordinary JJ 50458 1204 6 spider spider NN 50458 1204 7 occasions occasion NNS 50458 1204 8 simply simply RB 50458 1204 9 a a DT 50458 1204 10 slight slight JJ 50458 1204 11 local local JJ 50458 1204 12 pain pain NN 50458 1204 13 , , , 50458 1204 14 with with IN 50458 1204 15 redness redness NN 50458 1204 16 ; ; : 50458 1204 17 that that DT 50458 1204 18 of of IN 50458 1204 19 the the DT 50458 1204 20 large large JJ 50458 1204 21 poisonous poisonous JJ 50458 1204 22 spider spider NN 50458 1204 23 , , , 50458 1204 24 however however RB 50458 1204 25 , , , 50458 1204 26 may may MD 50458 1204 27 kill kill VB 50458 1204 28 the the DT 50458 1204 29 larger large JJR 50458 1204 30 animals animal NNS 50458 1204 31 , , , 50458 1204 32 and and CC 50458 1204 33 even even RB 50458 1204 34 man man NN 50458 1204 35 . . . 50458 1205 1 [ [ -LRB- 50458 1205 2 159 159 CD 50458 1205 3 ] ] -RRB- 50458 1205 4 JOYEUX JOYEUX NNP 50458 1205 5 - - HYPH 50458 1205 6 LAFFRIÉE LAFFRIÉE NNP 50458 1205 7 : : : 50458 1205 8 _ _ NNP 50458 1205 9 Thèse Thèse NNP 50458 1205 10 de de NNP 50458 1205 11 doctorat doctorat FW 50458 1205 12 en en FW 50458 1205 13 Médecine Médecine NNP 50458 1205 14 _ _ NNP 50458 1205 15 , , , 50458 1205 16 Paris Paris NNP 50458 1205 17 , , , 50458 1205 18 1883 1883 CD 50458 1205 19 ; ; : 50458 1205 20 P. P. NNP 50458 1205 21 BERT BERT NNP 50458 1205 22 : : : 50458 1205 23 _ _ NNP 50458 1205 24 Compt Compt NNP 50458 1205 25 . . . 50458 1206 1 rend rend VB 50458 1206 2 . . . 50458 1207 1 de de NNP 50458 1207 2 la la NNP 50458 1207 3 Soc Soc NNP 50458 1207 4 . . . 50458 1208 1 de de NNP 50458 1208 2 Biol Biol NNP 50458 1208 3 . . . 50458 1208 4 _ _ NNP 50458 1208 5 , , , 50458 1208 6 II II NNP 50458 1208 7 [ [ -LRB- 50458 1208 8 4 4 CD 50458 1208 9 ] ] -RRB- 50458 1208 10 , , , 50458 1208 11 p. p. NN 50458 1208 12 136 136 CD 50458 1208 13 . . . 50458 1209 1 = = NFP 50458 1209 2 Poison poison NN 50458 1209 3 of of IN 50458 1209 4 Scorpions.=[160]--This scorpions.=[160]--this JJ 50458 1209 5 poison poison NN 50458 1209 6 is be VBZ 50458 1209 7 a a DT 50458 1209 8 colorless colorless JJ 50458 1209 9 , , , 50458 1209 10 acid acid JJ 50458 1209 11 liquid liquid NN 50458 1209 12 , , , 50458 1209 13 having have VBG 50458 1209 14 a a DT 50458 1209 15 higher high JJR 50458 1209 16 specific specific JJ 50458 1209 17 gravity gravity NN 50458 1209 18 than than IN 50458 1209 19 water water NN 50458 1209 20 , , , 50458 1209 21 in in IN 50458 1209 22 which which WDT 50458 1209 23 liquid liquid NN 50458 1209 24 it -PRON- PRP 50458 1209 25 is be VBZ 50458 1209 26 soluble soluble JJ 50458 1209 27 . . . 50458 1210 1 The the DT 50458 1210 2 famed famed JJ 50458 1210 3 legend legend NN 50458 1210 4 of of IN 50458 1210 5 the the DT 50458 1210 6 suicide suicide NN 50458 1210 7 of of IN 50458 1210 8 scorpions scorpion NNS 50458 1210 9 is be VBZ 50458 1210 10 well well RB 50458 1210 11 known known JJ 50458 1210 12 to to IN 50458 1210 13 all all DT 50458 1210 14 . . . 50458 1211 1 It -PRON- PRP 50458 1211 2 is be VBZ 50458 1211 3 stated state VBN 50458 1211 4 that that IN 50458 1211 5 when when WRB 50458 1211 6 the the DT 50458 1211 7 insect insect NN 50458 1211 8 finds find VBZ 50458 1211 9 itself -PRON- PRP 50458 1211 10 in in IN 50458 1211 11 a a DT 50458 1211 12 position position NN 50458 1211 13 where where WRB 50458 1211 14 its -PRON- PRP$ 50458 1211 15 death death NN 50458 1211 16 is be VBZ 50458 1211 17 inevitable inevitable JJ 50458 1211 18 , , , 50458 1211 19 it -PRON- PRP 50458 1211 20 stings sting VBZ 50458 1211 21 itself -PRON- PRP 50458 1211 22 , , , 50458 1211 23 and and CC 50458 1211 24 dies die VBZ 50458 1211 25 from from IN 50458 1211 26 the the DT 50458 1211 27 effects effect NNS 50458 1211 28 of of IN 50458 1211 29 its -PRON- PRP$ 50458 1211 30 own own JJ 50458 1211 31 poison poison NN 50458 1211 32 . . . 50458 1212 1 A a DT 50458 1212 2 simple simple JJ 50458 1212 3 method method NN 50458 1212 4 has have VBZ 50458 1212 5 even even RB 50458 1212 6 been be VBN 50458 1212 7 described describe VBN 50458 1212 8 of of IN 50458 1212 9 bringing bring VBG 50458 1212 10 this this DT 50458 1212 11 result result NN 50458 1212 12 about about IN 50458 1212 13 experimentally experimentally RB 50458 1212 14 by by IN 50458 1212 15 surrounding surround VBG 50458 1212 16 the the DT 50458 1212 17 insect insect NN 50458 1212 18 with with IN 50458 1212 19 a a DT 50458 1212 20 circle circle NN 50458 1212 21 of of IN 50458 1212 22 fire fire NN 50458 1212 23 . . . 50458 1213 1 Bounne Bounne NNP 50458 1213 2 , , , 50458 1213 3 of of IN 50458 1213 4 Madras,[161 Madras,[161 NNP 50458 1213 5 ] ] -RRB- 50458 1213 6 who who WP 50458 1213 7 has have VBZ 50458 1213 8 studied study VBN 50458 1213 9 the the DT 50458 1213 10 procedure procedure NN 50458 1213 11 , , , 50458 1213 12 has have VBZ 50458 1213 13 demonstrated demonstrate VBN 50458 1213 14 its -PRON- PRP$ 50458 1213 15 entire entire JJ 50458 1213 16 falsity falsity NN 50458 1213 17 by by IN 50458 1213 18 showing show VBG 50458 1213 19 , , , 50458 1213 20 first first RB 50458 1213 21 of of IN 50458 1213 22 all all DT 50458 1213 23 , , , 50458 1213 24 that that IN 50458 1213 25 the the DT 50458 1213 26 insect insect NN 50458 1213 27 dies die VBZ 50458 1213 28 from from IN 50458 1213 29 the the DT 50458 1213 30 effects effect NNS 50458 1213 31 of of IN 50458 1213 32 the the DT 50458 1213 33 excessive excessive JJ 50458 1213 34 heat heat NN 50458 1213 35 , , , 50458 1213 36 and and CC 50458 1213 37 further far RBR 50458 1213 38 , , , 50458 1213 39 that that IN 50458 1213 40 the the DT 50458 1213 41 poison poison NN 50458 1213 42 of of IN 50458 1213 43 the the DT 50458 1213 44 scorpion scorpion NN 50458 1213 45 is be VBZ 50458 1213 46 harmless harmless JJ 50458 1213 47 to to IN 50458 1213 48 individuals individual NNS 50458 1213 49 of of IN 50458 1213 50 the the DT 50458 1213 51 species specie NNS 50458 1213 52 that that WDT 50458 1213 53 furnish furnish VBP 50458 1213 54 it -PRON- PRP 50458 1213 55 . . . 50458 1214 1 [ [ -LRB- 50458 1214 2 160 160 CD 50458 1214 3 ] ] -RRB- 50458 1214 4 CALMETTE CALMETTE NNP 50458 1214 5 : : : 50458 1214 6 _ _ NNP 50458 1214 7 Annales Annales NNP 50458 1214 8 de de NNP 50458 1214 9 l'Instit l'Instit NNP 50458 1214 10 . . . 50458 1215 1 Pasteur Pasteur NNP 50458 1215 2 _ _ NNP 50458 1215 3 , , , 50458 1215 4 X X NNP 50458 1215 5 , , , 50458 1215 6 p. p. NN 50458 1215 7 232 232 CD 50458 1215 8 . . . 50458 1216 1 [ [ -LRB- 50458 1216 2 161 161 CD 50458 1216 3 ] ] -RRB- 50458 1216 4 _ _ NNP 50458 1216 5 Proceedings Proceedings NNP 50458 1216 6 of of IN 50458 1216 7 the the DT 50458 1216 8 Royal Royal NNP 50458 1216 9 Society Society NNP 50458 1216 10 _ _ NNP 50458 1216 11 , , , 50458 1216 12 XLII XLII NNP 50458 1216 13 , , , 50458 1216 14 p. p. NN 50458 1216 15 17 17 CD 50458 1216 16 . . . 50458 1217 1 Metchinkoff[162 metchinkoff[162 NN 50458 1217 2 ] ] -RRB- 50458 1217 3 has have VBZ 50458 1217 4 confirmed confirm VBN 50458 1217 5 these these DT 50458 1217 6 facts fact NNS 50458 1217 7 , , , 50458 1217 8 and and CC 50458 1217 9 has have VBZ 50458 1217 10 moreover moreover RB 50458 1217 11 demonstrated demonstrate VBN 50458 1217 12 that that IN 50458 1217 13 the the DT 50458 1217 14 blood blood NN 50458 1217 15 of of IN 50458 1217 16 the the DT 50458 1217 17 scorpion scorpion NN 50458 1217 18 possesses possess VBZ 50458 1217 19 an an DT 50458 1217 20 undoubted undoubted JJ 50458 1217 21 antitoxic antitoxic NN 50458 1217 22 power power NN 50458 1217 23 against against IN 50458 1217 24 the the DT 50458 1217 25 poison poison NN 50458 1217 26 of of IN 50458 1217 27 the the DT 50458 1217 28 insect insect NN 50458 1217 29 . . . 50458 1218 1 [ [ -LRB- 50458 1218 2 162 162 CD 50458 1218 3 ] ] -RRB- 50458 1218 4 METCHNIKOFF METCHNIKOFF NNP 50458 1218 5 : : : 50458 1218 6 _ _ NNP 50458 1218 7 L'Immunité L'Immunité NNP 50458 1218 8 _ _ NNP 50458 1218 9 , , , 50458 1218 10 p. p. NN 50458 1218 11 344 344 CD 50458 1218 12 . . . 50458 1219 1 The the DT 50458 1219 2 poison poison NN 50458 1219 3 of of IN 50458 1219 4 the the DT 50458 1219 5 scorpion scorpion NN 50458 1219 6 serves serve VBZ 50458 1219 7 it -PRON- PRP 50458 1219 8 to to TO 50458 1219 9 kill kill VB 50458 1219 10 the the DT 50458 1219 11 insects insect NNS 50458 1219 12 which which WDT 50458 1219 13 are be VBP 50458 1219 14 its -PRON- PRP$ 50458 1219 15 prey prey NN 50458 1219 16 . . . 50458 1220 1 Frogs frog NNS 50458 1220 2 and and CC 50458 1220 3 birds bird NNS 50458 1220 4 stung sting VBN 50458 1220 5 by by IN 50458 1220 6 the the DT 50458 1220 7 scorpion scorpion NN 50458 1220 8 also also RB 50458 1220 9 generally generally RB 50458 1220 10 die die VBP 50458 1220 11 . . . 50458 1221 1 A a DT 50458 1221 2 dose dose NN 50458 1221 3 of of IN 50458 1221 4 0.0005 0.0005 NNP 50458 1221 5 Gm Gm NNP 50458 1221 6 . . . 50458 1222 1 kills kill VBZ 50458 1222 2 a a DT 50458 1222 3 guinea guinea NN 50458 1222 4 - - HYPH 50458 1222 5 pig pig NN 50458 1222 6 in in IN 50458 1222 7 less less JJR 50458 1222 8 than than IN 50458 1222 9 one one CD 50458 1222 10 hour hour NN 50458 1222 11 ; ; : 50458 1222 12 and and CC 50458 1222 13 according accord VBG 50458 1222 14 to to IN 50458 1222 15 Calmette[163 Calmette[163 NNP 50458 1222 16 ] ] -RRB- 50458 1222 17 less less JJR 50458 1222 18 than than IN 50458 1222 19 0.0005 0.0005 NNP 50458 1222 20 will will MD 50458 1222 21 kill kill VB 50458 1222 22 a a DT 50458 1222 23 white white JJ 50458 1222 24 mouse mouse NN 50458 1222 25 in in IN 50458 1222 26 two two CD 50458 1222 27 hours hour NNS 50458 1222 28 . . . 50458 1223 1 Oxidizers oxidizer NNS 50458 1223 2 destroy destroy VBP 50458 1223 3 the the DT 50458 1223 4 toxicity toxicity NN 50458 1223 5 of of IN 50458 1223 6 the the DT 50458 1223 7 poison poison NN 50458 1223 8 . . . 50458 1224 1 Guinea guinea NN 50458 1224 2 - - HYPH 50458 1224 3 pigs pig NNS 50458 1224 4 immunized immunize VBN 50458 1224 5 against against IN 50458 1224 6 the the DT 50458 1224 7 poison poison NN 50458 1224 8 of of IN 50458 1224 9 the the DT 50458 1224 10 scorpion scorpion NN 50458 1224 11 resist resist VBP 50458 1224 12 perfectly perfectly RB 50458 1224 13 very very RB 50458 1224 14 large large JJ 50458 1224 15 doses dose NNS 50458 1224 16 of of IN 50458 1224 17 the the DT 50458 1224 18 poison poison NN 50458 1224 19 . . . 50458 1225 1 [ [ -LRB- 50458 1225 2 163 163 CD 50458 1225 3 ] ] -RRB- 50458 1225 4 CALMETTE CALMETTE NNP 50458 1225 5 : : : 50458 1225 6 _ _ NNP 50458 1225 7 Annal Annal NNP 50458 1225 8 . . . 50458 1226 1 de de NNP 50458 1226 2 l'Instit l'Instit NNP 50458 1226 3 . . . 50458 1227 1 Pasteur Pasteur NNP 50458 1227 2 _ _ NNP 50458 1227 3 , , , 50458 1227 4 X X NNP 50458 1227 5 , , , 50458 1227 6 p. p. NN 50458 1227 7 232 232 CD 50458 1227 8 . . . 50458 1228 1 = = NFP 50458 1228 2 Poisonous Poisonous NNP 50458 1228 3 Blood Blood NNP 50458 1228 4 and and CC 50458 1228 5 Serums.=--It Serums.=--It NNP 50458 1228 6 is be VBZ 50458 1228 7 an an DT 50458 1228 8 almost almost RB 50458 1228 9 general general JJ 50458 1228 10 fact fact NN 50458 1228 11 that that IN 50458 1228 12 the the DT 50458 1228 13 blood blood NN 50458 1228 14 and and CC 50458 1228 15 blood blood NN 50458 1228 16 serum serum NN 50458 1228 17 of of IN 50458 1228 18 batrachians batrachian NNS 50458 1228 19 , , , 50458 1228 20 eels eel NNS 50458 1228 21 , , , 50458 1228 22 lampreys lamprey NNS 50458 1228 23 , , , 50458 1228 24 snakes snake NNS 50458 1228 25 ( ( -LRB- 50458 1228 26 even even RB 50458 1228 27 non non JJ 50458 1228 28 - - JJ 50458 1228 29 poisonous poisonous JJ 50458 1228 30 ones one NNS 50458 1228 31 ) ) -RRB- 50458 1228 32 , , , 50458 1228 33 and and CC 50458 1228 34 hedgehogs hedgehog NNS 50458 1228 35 are be VBP 50458 1228 36 very very RB 50458 1228 37 poisonous poisonous JJ 50458 1228 38 . . . 50458 1229 1 Mosso Mosso NNP 50458 1229 2 has have VBZ 50458 1229 3 found find VBN 50458 1229 4 in in IN 50458 1229 5 the the DT 50458 1229 6 blood blood NN 50458 1229 7 serum serum NN 50458 1229 8 of of IN 50458 1229 9 the the DT 50458 1229 10 lamprey lamprey NNP 50458 1229 11 a a DT 50458 1229 12 toxin toxin NN 50458 1229 13 possessing possess VBG 50458 1229 14 a a DT 50458 1229 15 strong strong JJ 50458 1229 16 hemolytic hemolytic JJ 50458 1229 17 power power NN 50458 1229 18 , , , 50458 1229 19 and and CC 50458 1229 20 which which WDT 50458 1229 21 he -PRON- PRP 50458 1229 22 has have VBZ 50458 1229 23 named name VBN 50458 1229 24 _ _ NNP 50458 1229 25 ichthyotoxin ichthyotoxin NN 50458 1229 26 _ _ NNP 50458 1229 27 . . . 50458 1230 1 O.5 O.5 NNP 50458 1230 2 Cc Cc NNP 50458 1230 3 . . . 50458 1231 1 of of IN 50458 1231 2 this this DT 50458 1231 3 serum serum NN 50458 1231 4 injected inject VBN 50458 1231 5 into into IN 50458 1231 6 a a DT 50458 1231 7 dog dog NN 50458 1231 8 kills kill VBZ 50458 1231 9 it -PRON- PRP 50458 1231 10 in in IN 50458 1231 11 a a DT 50458 1231 12 few few JJ 50458 1231 13 minutes minute NNS 50458 1231 14 . . . 50458 1232 1 He -PRON- PRP 50458 1232 2 also also RB 50458 1232 3 observed observe VBD 50458 1232 4 , , , 50458 1232 5 in in IN 50458 1232 6 1888 1888 CD 50458 1232 7 , , , 50458 1232 8 that that IN 50458 1232 9 the the DT 50458 1232 10 blood blood NN 50458 1232 11 of of IN 50458 1232 12 the the DT 50458 1232 13 eel eel NN 50458 1232 14 , , , 50458 1232 15 in in IN 50458 1232 16 like like UH 50458 1232 17 dose dose NN 50458 1232 18 , , , 50458 1232 19 kills kill VBZ 50458 1232 20 a a DT 50458 1232 21 dog dog NN 50458 1232 22 almost almost RB 50458 1232 23 immediately immediately RB 50458 1232 24 , , , 50458 1232 25 and and CC 50458 1232 26 that that IN 50458 1232 27 the the DT 50458 1232 28 blood blood NN 50458 1232 29 contains contain VBZ 50458 1232 30 an an DT 50458 1232 31 ichthyotoxin ichthyotoxin NN 50458 1232 32 analogous analogous JJ 50458 1232 33 to to IN 50458 1232 34 that that DT 50458 1232 35 of of IN 50458 1232 36 the the DT 50458 1232 37 lamprey lamprey NN 50458 1232 38 . . . 50458 1233 1 This this DT 50458 1233 2 substance substance NN 50458 1233 3 , , , 50458 1233 4 which which WDT 50458 1233 5 appears appear VBZ 50458 1233 6 to to TO 50458 1233 7 be be VB 50458 1233 8 closely closely RB 50458 1233 9 allied ally VBN 50458 1233 10 to to IN 50458 1233 11 the the DT 50458 1233 12 sero sero NN 50458 1233 13 - - : 50458 1233 14 albumin albumin NN 50458 1233 15 of of IN 50458 1233 16 the the DT 50458 1233 17 blood blood NN 50458 1233 18 , , , 50458 1233 19 has have VBZ 50458 1233 20 a a DT 50458 1233 21 phosphorus phosphorus NN 50458 1233 22 - - HYPH 50458 1233 23 like like JJ 50458 1233 24 , , , 50458 1233 25 sharp sharp JJ 50458 1233 26 , , , 50458 1233 27 and and CC 50458 1233 28 burning burn VBG 50458 1233 29 taste taste NN 50458 1233 30 . . . 50458 1234 1 By by IN 50458 1234 2 digestion digestion NN 50458 1234 3 it -PRON- PRP 50458 1234 4 loses lose VBZ 50458 1234 5 its -PRON- PRP$ 50458 1234 6 toxicity toxicity NN 50458 1234 7 , , , 50458 1234 8 as as RB 50458 1234 9 well well RB 50458 1234 10 as as IN 50458 1234 11 by by IN 50458 1234 12 heating heating NN 50458 1234 13 at at IN 50458 1234 14 68 68 CD 50458 1234 15 ° ° NNS 50458 1234 16 to to IN 50458 1234 17 70 70 CD 50458 1234 18 ° ° , 50458 1234 19 C. C. NNP 50458 1234 20 It -PRON- PRP 50458 1234 21 is be VBZ 50458 1234 22 easily easily RB 50458 1234 23 obtained obtain VBN 50458 1234 24 by by IN 50458 1234 25 precipitating precipitate VBG 50458 1234 26 with with IN 50458 1234 27 ammonium ammonium NN 50458 1234 28 sulphate sulphate VBP 50458 1234 29 the the DT 50458 1234 30 serum serum NN 50458 1234 31 of of IN 50458 1234 32 eels eel NNS 50458 1234 33 , , , 50458 1234 34 and and CC 50458 1234 35 dialyzing dialyze VBG 50458 1234 36 the the DT 50458 1234 37 precipitate precipitate NN 50458 1234 38 dissolved dissolve VBN 50458 1234 39 in in IN 50458 1234 40 water water NN 50458 1234 41 . . . 50458 1235 1 The the DT 50458 1235 2 power power NN 50458 1235 3 of of IN 50458 1235 4 this this DT 50458 1235 5 substance substance NN 50458 1235 6 is be VBZ 50458 1235 7 almost almost RB 50458 1235 8 as as RB 50458 1235 9 great great JJ 50458 1235 10 as as IN 50458 1235 11 that that DT 50458 1235 12 of of IN 50458 1235 13 the the DT 50458 1235 14 cobra cobra NN 50458 1235 15 poison poison NN 50458 1235 16 , , , 50458 1235 17 0.002 0.002 CD 50458 1235 18 Gm Gm NNP 50458 1235 19 . . . 50458 1236 1 being be VBG 50458 1236 2 instantly instantly RB 50458 1236 3 fatal fatal JJ 50458 1236 4 per per IN 50458 1236 5 kilo kilo NN 50458 1236 6 of of IN 50458 1236 7 dog dog NN 50458 1236 8 . . . 50458 1237 1 The the DT 50458 1237 2 blood blood NN 50458 1237 3 of of IN 50458 1237 4 snakes snake NNS 50458 1237 5 is be VBZ 50458 1237 6 likewise likewise RB 50458 1237 7 very very RB 50458 1237 8 toxic toxic JJ 50458 1237 9 ; ; : 50458 1237 10 the the DT 50458 1237 11 same same JJ 50458 1237 12 is be VBZ 50458 1237 13 true true JJ 50458 1237 14 of of IN 50458 1237 15 the the DT 50458 1237 16 blood blood NN 50458 1237 17 of of IN 50458 1237 18 the the DT 50458 1237 19 viper viper NN 50458 1237 20 , , , 50458 1237 21 as as IN 50458 1237 22 0.02 0.02 CD 50458 1237 23 Cc Cc NNP 50458 1237 24 . . . 50458 1238 1 will will MD 50458 1238 2 kill kill VB 50458 1238 3 a a DT 50458 1238 4 guinea guinea NN 50458 1238 5 - - HYPH 50458 1238 6 pig pig NN 50458 1238 7 in in IN 50458 1238 8 two two CD 50458 1238 9 hours hour NNS 50458 1238 10 . . . 50458 1239 1 All all PDT 50458 1239 2 these these DT 50458 1239 3 bloods blood NNS 50458 1239 4 lose lose VBP 50458 1239 5 their -PRON- PRP$ 50458 1239 6 toxicity toxicity NN 50458 1239 7 when when WRB 50458 1239 8 heated heat VBN 50458 1239 9 above above IN 50458 1239 10 70 70 CD 50458 1239 11 ° ° , 50458 1239 12 C. C. NNP 50458 1239 13 The the DT 50458 1239 14 serum serum NN 50458 1239 15 of of IN 50458 1239 16 the the DT 50458 1239 17 hedgehog hedgehog NN 50458 1239 18 is be VBZ 50458 1239 19 peculiar peculiar JJ 50458 1239 20 in in IN 50458 1239 21 this this DT 50458 1239 22 respect respect NN 50458 1239 23 ; ; : 50458 1239 24 when when WRB 50458 1239 25 heated heat VBN 50458 1239 26 at at IN 50458 1239 27 38 38 CD 50458 1239 28 ° ° , 50458 1239 29 C. C. NNP 50458 1239 30 for for IN 50458 1239 31 fifteen fifteen CD 50458 1239 32 minutes minute NNS 50458 1239 33 it -PRON- PRP 50458 1239 34 loses lose VBZ 50458 1239 35 its -PRON- PRP$ 50458 1239 36 toxicity toxicity NN 50458 1239 37 , , , 50458 1239 38 but but CC 50458 1239 39 it -PRON- PRP 50458 1239 40 then then RB 50458 1239 41 possesses possess VBZ 50458 1239 42 an an DT 50458 1239 43 immunizing immunize VBG 50458 1239 44 power power NN 50458 1239 45 against against IN 50458 1239 46 the the DT 50458 1239 47 poisons poison NNS 50458 1239 48 . . . 50458 1240 1 The the DT 50458 1240 2 subject subject JJ 50458 1240 3 possesses possess VBZ 50458 1240 4 great great JJ 50458 1240 5 interest interest NN 50458 1240 6 , , , 50458 1240 7 because because IN 50458 1240 8 it -PRON- PRP 50458 1240 9 was be VBD 50458 1240 10 in in IN 50458 1240 11 studying study VBG 50458 1240 12 these these DT 50458 1240 13 immunizing immunize VBG 50458 1240 14 properties property NNS 50458 1240 15 that that WDT 50458 1240 16 Camus Camus NNP 50458 1240 17 and and CC 50458 1240 18 Gley,[164 Gley,[164 NNP 50458 1240 19 ] ] -RRB- 50458 1240 20 and and CC 50458 1240 21 later later RB 50458 1240 22 on on IN 50458 1240 23 Kossel[165 Kossel[165 NNP 50458 1240 24 ] ] -RRB- 50458 1240 25 and and CC 50458 1240 26 Tchistowitch,[166 tchistowitch,[166 CD 50458 1240 27 ] ] -RRB- 50458 1240 28 discovered discover VBD 50458 1240 29 the the DT 50458 1240 30 first first JJ 50458 1240 31 anticytotoxin,[167 anticytotoxin,[167 NN 50458 1240 32 ] ] -RRB- 50458 1240 33 which which WDT 50458 1240 34 they -PRON- PRP 50458 1240 35 obtained obtain VBD 50458 1240 36 by by IN 50458 1240 37 treating treat VBG 50458 1240 38 the the DT 50458 1240 39 animals animal NNS 50458 1240 40 with with IN 50458 1240 41 increasing increase VBG 50458 1240 42 quantities quantity NNS 50458 1240 43 of of IN 50458 1240 44 the the DT 50458 1240 45 serum serum NN 50458 1240 46 of of IN 50458 1240 47 eels eel NNS 50458 1240 48 . . . 50458 1241 1 On on IN 50458 1241 2 mixing mix VBG 50458 1241 3 the the DT 50458 1241 4 antitoxic antitoxic NN 50458 1241 5 serum serum NN 50458 1241 6 of of IN 50458 1241 7 these these DT 50458 1241 8 animals animal NNS 50458 1241 9 _ _ NNP 50458 1241 10 in in IN 50458 1241 11 vitro vitro FW 50458 1241 12 _ _ NNP 50458 1241 13 with with IN 50458 1241 14 the the DT 50458 1241 15 red red JJ 50458 1241 16 blood blood NN 50458 1241 17 - - HYPH 50458 1241 18 corpuscles corpuscle NNS 50458 1241 19 of of IN 50458 1241 20 the the DT 50458 1241 21 species specie NNS 50458 1241 22 furnishing furnish VBG 50458 1241 23 the the DT 50458 1241 24 serum serum NN 50458 1241 25 and and CC 50458 1241 26 of of IN 50458 1241 27 the the DT 50458 1241 28 hemolytic hemolytic JJ 50458 1241 29 serum serum NN 50458 1241 30 of of IN 50458 1241 31 eels eel NNS 50458 1241 32 , , , 50458 1241 33 it -PRON- PRP 50458 1241 34 is be VBZ 50458 1241 35 found find VBN 50458 1241 36 that that IN 50458 1241 37 the the DT 50458 1241 38 blood blood NN 50458 1241 39 - - HYPH 50458 1241 40 corpuscles corpuscle NNS 50458 1241 41 kept keep VBD 50458 1241 42 quite quite RB 50458 1241 43 well well RB 50458 1241 44 . . . 50458 1242 1 [ [ -LRB- 50458 1242 2 164 164 CD 50458 1242 3 ] ] -RRB- 50458 1242 4 _ _ NNP 50458 1242 5 Archives Archives NNP 50458 1242 6 internat internat NN 50458 1242 7 . . . 50458 1243 1 de de NNP 50458 1243 2 Pharmacodynamie Pharmacodynamie NNP 50458 1243 3 _ _ NNP 50458 1243 4 , , , 50458 1243 5 III III NNP 50458 1243 6 and and CC 50458 1243 7 IV IV NNP 50458 1243 8 . . . 50458 1244 1 [ [ -LRB- 50458 1244 2 165 165 CD 50458 1244 3 ] ] -RRB- 50458 1244 4 _ _ NNP 50458 1244 5 Berliner Berliner NNP 50458 1244 6 Klin Klin NNP 50458 1244 7 . . . 50458 1245 1 Wochenschr Wochenschr NNP 50458 1245 2 . . . 50458 1245 3 _ _ NNP 50458 1245 4 , , , 50458 1245 5 1895 1895 CD 50458 1245 6 , , , 50458 1245 7 No no UH 50458 1245 8 . . . 50458 1246 1 7 7 LS 50458 1246 2 . . . 50458 1247 1 [ [ -LRB- 50458 1247 2 166 166 CD 50458 1247 3 ] ] -RRB- 50458 1247 4 _ _ NNP 50458 1247 5 Annal Annal NNP 50458 1247 6 . . . 50458 1248 1 de de NNP 50458 1248 2 l'Instit l'Instit NNP 50458 1248 3 . . . 50458 1249 1 Pasteur Pasteur NNP 50458 1249 2 _ _ NNP 50458 1249 3 , , , 50458 1249 4 XIII XIII NNP 50458 1249 5 , , , 50458 1249 6 p. p. NN 50458 1249 7 406 406 CD 50458 1249 8 . . . 50458 1250 1 [ [ -LRB- 50458 1250 2 167 167 CD 50458 1250 3 ] ] -RRB- 50458 1250 4 The the DT 50458 1250 5 name name NN 50458 1250 6 " " `` 50458 1250 7 cytases cytase VBZ 50458 1250 8 " " '' 50458 1250 9 or or CC 50458 1250 10 " " `` 50458 1250 11 alexins alexin NNS 50458 1250 12 " " '' 50458 1250 13 has have VBZ 50458 1250 14 been be VBN 50458 1250 15 given give VBN 50458 1250 16 to to IN 50458 1250 17 hemolyzing hemolyzing JJ 50458 1250 18 diastatic diastatic JJ 50458 1250 19 substances substance NNS 50458 1250 20 which which WDT 50458 1250 21 are be VBP 50458 1250 22 found find VBN 50458 1250 23 in in IN 50458 1250 24 certain certain JJ 50458 1250 25 serums serum NNS 50458 1250 26 . . . 50458 1251 1 It -PRON- PRP 50458 1251 2 has have VBZ 50458 1251 3 been be VBN 50458 1251 4 known know VBN 50458 1251 5 for for IN 50458 1251 6 a a DT 50458 1251 7 long long JJ 50458 1251 8 time time NN 50458 1251 9 that that IN 50458 1251 10 the the DT 50458 1251 11 serum serum NN 50458 1251 12 of of IN 50458 1251 13 the the DT 50458 1251 14 blood blood NN 50458 1251 15 of of IN 50458 1251 16 many many JJ 50458 1251 17 animals animal NNS 50458 1251 18 destroys destroy VBZ 50458 1251 19 the the DT 50458 1251 20 red red JJ 50458 1251 21 blood blood NN 50458 1251 22 - - HYPH 50458 1251 23 corpuscles corpuscle NNS 50458 1251 24 of of IN 50458 1251 25 other other JJ 50458 1251 26 and and CC 50458 1251 27 different different JJ 50458 1251 28 species specie NNS 50458 1251 29 . . . 50458 1252 1 The the DT 50458 1252 2 chemical chemical JJ 50458 1252 3 composition composition NN 50458 1252 4 of of IN 50458 1252 5 these these DT 50458 1252 6 cytases cytase NNS 50458 1252 7 or or CC 50458 1252 8 alexins alexin NNS 50458 1252 9 is be VBZ 50458 1252 10 not not RB 50458 1252 11 yet yet RB 50458 1252 12 definitely definitely RB 50458 1252 13 known know VBN 50458 1252 14 , , , 50458 1252 15 but but CC 50458 1252 16 the the DT 50458 1252 17 substances substance NNS 50458 1252 18 rank rank VBP 50458 1252 19 among among IN 50458 1252 20 the the DT 50458 1252 21 albuminoids albuminoid NNS 50458 1252 22 ; ; : 50458 1252 23 they -PRON- PRP 50458 1252 24 are be VBP 50458 1252 25 destroyed destroy VBN 50458 1252 26 by by IN 50458 1252 27 a a DT 50458 1252 28 temperature temperature NN 50458 1252 29 of of IN 50458 1252 30 55 55 CD 50458 1252 31 ° ° NNS 50458 1252 32 to to IN 50458 1252 33 56 56 CD 50458 1252 34 ° ° NNS 50458 1252 35 C. C. NNP 50458 1252 36 , , , 50458 1252 37 and and CC 50458 1252 38 act act VB 50458 1252 39 only only RB 50458 1252 40 in in IN 50458 1252 41 saline saline JJ 50458 1252 42 solutions solution NNS 50458 1252 43 ( ( -LRB- 50458 1252 44 Ehrlich Ehrlich NNP 50458 1252 45 and and CC 50458 1252 46 Morgenroth Morgenroth NNP 50458 1252 47 , , , 50458 1252 48 _ _ NNP 50458 1252 49 Berlin Berlin NNP 50458 1252 50 . . . 50458 1253 1 Klin Klin NNP 50458 1253 2 . . . 50458 1254 1 Woch Woch NNP 50458 1254 2 . . . 50458 1254 3 _ _ NNP 50458 1254 4 , , , 50458 1254 5 pp pp NNP 50458 1254 6 . . . 50458 1255 1 6 6 CD 50458 1255 2 and and CC 50458 1255 3 481 481 CD 50458 1255 4 ) ) -RRB- 50458 1255 5 . . . 50458 1256 1 The the DT 50458 1256 2 cytases cytase NNS 50458 1256 3 or or CC 50458 1256 4 alexins alexin NNS 50458 1256 5 , , , 50458 1256 6 which which WDT 50458 1256 7 will will MD 50458 1256 8 be be VB 50458 1256 9 studied study VBN 50458 1256 10 in in IN 50458 1256 11 another another DT 50458 1256 12 volume volume NN 50458 1256 13 of of IN 50458 1256 14 this this DT 50458 1256 15 collection collection NN 50458 1256 16 , , , 50458 1256 17 and and CC 50458 1256 18 which which WDT 50458 1256 19 will will MD 50458 1256 20 discuss discuss VB 50458 1256 21 the the DT 50458 1256 22 active active JJ 50458 1256 23 principles principle NNS 50458 1256 24 of of IN 50458 1256 25 the the DT 50458 1256 26 immunizing immunize VBG 50458 1256 27 serums serum NNS 50458 1256 28 , , , 50458 1256 29 constitute constitute VBP 50458 1256 30 one one CD 50458 1256 31 of of IN 50458 1256 32 the the DT 50458 1256 33 numerous numerous JJ 50458 1256 34 soluble soluble JJ 50458 1256 35 intraleucocytary intraleucocytary JJ 50458 1256 36 ferments ferment NNS 50458 1256 37 , , , 50458 1256 38 and and CC 50458 1256 39 they -PRON- PRP 50458 1256 40 pass pass VBP 50458 1256 41 into into IN 50458 1256 42 the the DT 50458 1256 43 serous serous JJ 50458 1256 44 liquids liquid NNS 50458 1256 45 of of IN 50458 1256 46 the the DT 50458 1256 47 organism organism NN 50458 1256 48 only only RB 50458 1256 49 as as IN 50458 1256 50 the the DT 50458 1256 51 result result NN 50458 1256 52 of of IN 50458 1256 53 a a DT 50458 1256 54 rupture rupture NN 50458 1256 55 of of IN 50458 1256 56 or or CC 50458 1256 57 injury injury NN 50458 1256 58 to to IN 50458 1256 59 the the DT 50458 1256 60 phagocytes phagocyte NNS 50458 1256 61 . . . 50458 1257 1 As as IN 50458 1257 2 to to IN 50458 1257 3 the the DT 50458 1257 4 blood blood NN 50458 1257 5 of of IN 50458 1257 6 the the DT 50458 1257 7 hedgehog hedgehog NN 50458 1257 8 , , , 50458 1257 9 we -PRON- PRP 50458 1257 10 have have VBP 50458 1257 11 already already RB 50458 1257 12 seen see VBN 50458 1257 13 that that IN 50458 1257 14 Physalix Physalix NNP 50458 1257 15 and and CC 50458 1257 16 Bertrand Bertrand NNP 50458 1257 17 have have VBP 50458 1257 18 shown show VBN 50458 1257 19 that that IN 50458 1257 20 it -PRON- PRP 50458 1257 21 may may MD 50458 1257 22 be be VB 50458 1257 23 a a DT 50458 1257 24 counter counter NN 50458 1257 25 - - NN 50458 1257 26 poison poison NN 50458 1257 27 towards towards IN 50458 1257 28 serpent serpent NN 50458 1257 29 - - HYPH 50458 1257 30 venom venom NN 50458 1257 31 under under IN 50458 1257 32 certain certain JJ 50458 1257 33 conditions condition NNS 50458 1257 34 . . . 50458 1258 1 In in IN 50458 1258 2 its -PRON- PRP$ 50458 1258 3 normal normal JJ 50458 1258 4 condition condition NN 50458 1258 5 it -PRON- PRP 50458 1258 6 is be VBZ 50458 1258 7 highly highly RB 50458 1258 8 toxic toxic JJ 50458 1258 9 . . . 50458 1259 1 = = NFP 50458 1259 2 Poisonous poisonous JJ 50458 1259 3 Meats.=--It Meats.=--It NNP 50458 1259 4 is be VBZ 50458 1259 5 particularly particularly RB 50458 1259 6 among among IN 50458 1259 7 the the DT 50458 1259 8 fish fish NN 50458 1259 9 that that WDT 50458 1259 10 we -PRON- PRP 50458 1259 11 find find VBP 50458 1259 12 these these DT 50458 1259 13 normally normally RB 50458 1259 14 present present JJ 50458 1259 15 , , , 50458 1259 16 and and CC 50458 1259 17 it -PRON- PRP 50458 1259 18 is be VBZ 50458 1259 19 a a DT 50458 1259 20 singular singular JJ 50458 1259 21 fact fact NN 50458 1259 22 that that IN 50458 1259 23 , , , 50458 1259 24 for for IN 50458 1259 25 a a DT 50458 1259 26 given give VBN 50458 1259 27 species species NN 50458 1259 28 , , , 50458 1259 29 the the DT 50458 1259 30 toxicity toxicity NN 50458 1259 31 frequently frequently RB 50458 1259 32 depends depend VBZ 50458 1259 33 upon upon IN 50458 1259 34 the the DT 50458 1259 35 period period NN 50458 1259 36 of of IN 50458 1259 37 the the DT 50458 1259 38 year year NN 50458 1259 39 . . . 50458 1260 1 Thus thus RB 50458 1260 2 , , , 50458 1260 3 at at IN 50458 1260 4 the the DT 50458 1260 5 period period NN 50458 1260 6 of of IN 50458 1260 7 spawning spawning NN 50458 1260 8 , , , 50458 1260 9 certain certain JJ 50458 1260 10 fish fish NN 50458 1260 11 may may MD 50458 1260 12 be be VB 50458 1260 13 extremely extremely RB 50458 1260 14 poisonous poisonous JJ 50458 1260 15 , , , 50458 1260 16 or or CC 50458 1260 17 , , , 50458 1260 18 on on IN 50458 1260 19 the the DT 50458 1260 20 contrary contrary NN 50458 1260 21 , , , 50458 1260 22 may may MD 50458 1260 23 entirely entirely RB 50458 1260 24 cease cease VB 50458 1260 25 to to TO 50458 1260 26 be be VB 50458 1260 27 so so RB 50458 1260 28 . . . 50458 1261 1 The the DT 50458 1261 2 anchovy anchovy JJ 50458 1261 3 ballassa ballassa NN 50458 1261 4 from from IN 50458 1261 5 the the DT 50458 1261 6 shores shore NNS 50458 1261 7 of of IN 50458 1261 8 India India NNP 50458 1261 9 occasions occasion NNS 50458 1261 10 death death NN 50458 1261 11 even even RB 50458 1261 12 in in IN 50458 1261 13 very very RB 50458 1261 14 small small JJ 50458 1261 15 quantity quantity NN 50458 1261 16 ; ; : 50458 1261 17 the the DT 50458 1261 18 poisonous poisonous JJ 50458 1261 19 meltite meltite NN 50458 1261 20 of of IN 50458 1261 21 the the DT 50458 1261 22 same same JJ 50458 1261 23 seas sea NNS 50458 1261 24 causes cause VBZ 50458 1261 25 violent violent JJ 50458 1261 26 vomiting vomiting NN 50458 1261 27 ; ; : 50458 1261 28 the the DT 50458 1261 29 fugu fugu NNS 50458 1261 30 of of IN 50458 1261 31 the the DT 50458 1261 32 Japanese japanese JJ 50458 1261 33 seas sea NNS 50458 1261 34 possesses possess VBZ 50458 1261 35 an an DT 50458 1261 36 extreme extreme JJ 50458 1261 37 poisonousness poisonousness NN 50458 1261 38 at at IN 50458 1261 39 the the DT 50458 1261 40 spawning spawning NN 50458 1261 41 period period NN 50458 1261 42 , , , 50458 1261 43 while while IN 50458 1261 44 , , , 50458 1261 45 on on IN 50458 1261 46 the the DT 50458 1261 47 contrary contrary NN 50458 1261 48 , , , 50458 1261 49 it -PRON- PRP 50458 1261 50 is be VBZ 50458 1261 51 perfectly perfectly RB 50458 1261 52 innocuous innocuous JJ 50458 1261 53 at at IN 50458 1261 54 all all DT 50458 1261 55 other other JJ 50458 1261 56 periods period NNS 50458 1261 57 . . . 50458 1262 1 Numerous numerous JJ 50458 1262 2 cases case NNS 50458 1262 3 of of IN 50458 1262 4 poisoning poisoning NN 50458 1262 5 have have VBP 50458 1262 6 been be VBN 50458 1262 7 chronicled chronicle VBN 50458 1262 8 every every DT 50458 1262 9 year year NN 50458 1262 10 by by IN 50458 1262 11 the the DT 50458 1262 12 journals journal NNS 50458 1262 13 , , , 50458 1262 14 due due IN 50458 1262 15 to to IN 50458 1262 16 the the DT 50458 1262 17 ingestion ingestion NN 50458 1262 18 of of IN 50458 1262 19 mussels mussel NNS 50458 1262 20 ; ; : 50458 1262 21 in in IN 50458 1262 22 the the DT 50458 1262 23 flesh flesh NN 50458 1262 24 of of IN 50458 1262 25 these these DT 50458 1262 26 crustaceæ crustaceæ NN 50458 1262 27 is be VBZ 50458 1262 28 found find VBN 50458 1262 29 a a DT 50458 1262 30 dangerous dangerous JJ 50458 1262 31 toxin toxin NN 50458 1262 32 , , , 50458 1262 33 _ _ NNP 50458 1262 34 methylotoxin methylotoxin NNP 50458 1262 35 _ _ NNP 50458 1262 36 . . . 50458 1263 1 The the DT 50458 1263 2 flesh flesh NN 50458 1263 3 of of IN 50458 1263 4 oysters oyster NNS 50458 1263 5 is be VBZ 50458 1263 6 also also RB 50458 1263 7 unwholesome unwholesome JJ 50458 1263 8 at at IN 50458 1263 9 the the DT 50458 1263 10 spawning spawning NN 50458 1263 11 period period NN 50458 1263 12 . . . 50458 1264 1 The the DT 50458 1264 2 toxic toxic JJ 50458 1264 3 symptoms symptom NNS 50458 1264 4 caused cause VBN 50458 1264 5 by by IN 50458 1264 6 these these DT 50458 1264 7 animals animal NNS 50458 1264 8 become become VBP 50458 1264 9 apparent apparent JJ 50458 1264 10 in in IN 50458 1264 11 not not RB 50458 1264 12 less less JJR 50458 1264 13 than than IN 50458 1264 14 twenty twenty CD 50458 1264 15 - - HYPH 50458 1264 16 four four CD 50458 1264 17 hours hour NNS 50458 1264 18 after after IN 50458 1264 19 ingestion ingestion NN 50458 1264 20 . . . 50458 1265 1 The the DT 50458 1265 2 poisoning poisoning NN 50458 1265 3 due due IN 50458 1265 4 to to IN 50458 1265 5 these these DT 50458 1265 6 fresh fresh JJ 50458 1265 7 meats meat NNS 50458 1265 8 must must MD 50458 1265 9 not not RB 50458 1265 10 , , , 50458 1265 11 however however RB 50458 1265 12 , , , 50458 1265 13 be be VB 50458 1265 14 confounded confound VBN 50458 1265 15 with with IN 50458 1265 16 that that DT 50458 1265 17 caused cause VBN 50458 1265 18 by by IN 50458 1265 19 tainted tainted JJ 50458 1265 20 or or CC 50458 1265 21 spoiled spoil VBN 50458 1265 22 meats meat NNS 50458 1265 23 . . . 50458 1266 1 WORKS WORKS NNP 50458 1266 2 OF of IN 50458 1266 3 ALFRED ALFRED NNP 50458 1266 4 I. i. NN 50458 1266 5 COHN cohn NN 50458 1266 6 PUBLISHED publish VBN 50458 1266 7 BY by IN 50458 1266 8 JOHN JOHN NNP 50458 1266 9 WILEY WILEY NNP 50458 1266 10 & & CC 50458 1266 11 SONS SONS NNP 50458 1266 12 . . . 50458 1267 1 = = NFP 50458 1267 2 Indicators Indicators NNP 50458 1267 3 and and CC 50458 1267 4 Test Test NNP 50458 1267 5 - - HYPH 50458 1267 6 papers.= papers.= NNP 50458 1267 7 Their -PRON- PRP$ 50458 1267 8 Source Source NNP 50458 1267 9 , , , 50458 1267 10 Preparation Preparation NNP 50458 1267 11 , , , 50458 1267 12 Application Application NNP 50458 1267 13 , , , 50458 1267 14 and and CC 50458 1267 15 Tests Tests NNPS 50458 1267 16 for for IN 50458 1267 17 Sensitiveness Sensitiveness NNP 50458 1267 18 . . . 50458 1268 1 With with IN 50458 1268 2 Tabular Tabular NNP 50458 1268 3 Summary Summary NNP 50458 1268 4 of of IN 50458 1268 5 the the DT 50458 1268 6 Application Application NNP 50458 1268 7 of of IN 50458 1268 8 Indicators Indicators NNPS 50458 1268 9 . . . 50458 1269 1 Second Second NNP 50458 1269 2 Edition Edition NNP 50458 1269 3 , , , 50458 1269 4 Revised Revised NNP 50458 1269 5 and and CC 50458 1269 6 Enlarged Enlarged NNP 50458 1269 7 . . . 50458 1270 1 12mo 12mo JJ 50458 1270 2 , , , 50458 1270 3 ix ix NN 50458 1270 4 + + CC 50458 1270 5 267 267 CD 50458 1270 6 pages page NNS 50458 1270 7 . . . 50458 1271 1 Cloth cloth NN 50458 1271 2 , , , 50458 1271 3 $ $ $ 50458 1271 4 2.00 2.00 CD 50458 1271 5 . . . 50458 1272 1 = = NFP 50458 1272 2 Tests test NNS 50458 1272 3 and and CC 50458 1272 4 Reagents.= Reagents.= NNP 50458 1272 5 Chemical Chemical NNP 50458 1272 6 and and CC 50458 1272 7 Microscopical Microscopical NNP 50458 1272 8 , , , 50458 1272 9 known know VBN 50458 1272 10 by by IN 50458 1272 11 their -PRON- PRP$ 50458 1272 12 Authors author NNS 50458 1272 13 ' ' POS 50458 1272 14 Names name NNS 50458 1272 15 ; ; : 50458 1272 16 together together RB 50458 1272 17 with with IN 50458 1272 18 an an DT 50458 1272 19 Index Index NNP 50458 1272 20 of of IN 50458 1272 21 Subjects Subjects NNPS 50458 1272 22 . . . 50458 1273 1 8vo 8vo NNP 50458 1273 2 , , , 50458 1273 3 iii iii CD 50458 1273 4 + + SYM 50458 1273 5 383 383 CD 50458 1273 6 pages page NNS 50458 1273 7 . . . 50458 1274 1 Cloth cloth NN 50458 1274 2 , , , 50458 1274 3 $ $ $ 50458 1274 4 3.00 3.00 CD 50458 1274 5 . . . 50458 1275 1 _ _ NNP 50458 1275 2 TRANSLATIONS TRANSLATIONS NNP 50458 1275 3 . . . 50458 1275 4 _ _ NNP 50458 1275 5 = = SYM 50458 1275 6 Fresenius Fresenius NNP 50458 1275 7 's 's POS 50458 1275 8 Quantitative Quantitative NNP 50458 1275 9 Chemical Chemical NNP 50458 1275 10 Analysis.= Analysis.= NNP 50458 1275 11 New New NNP 50458 1275 12 Authorized Authorized NNP 50458 1275 13 Translation Translation NNP 50458 1275 14 of of IN 50458 1275 15 the the DT 50458 1275 16 latest late JJS 50458 1275 17 German German NNP 50458 1275 18 Edition Edition NNP 50458 1275 19 . . . 50458 1276 1 In in IN 50458 1276 2 two two CD 50458 1276 3 volumes volume NNS 50458 1276 4 . . . 50458 1277 1 By by IN 50458 1277 2 Alfred Alfred NNP 50458 1277 3 I. I. NNP 50458 1277 4 Cohn Cohn NNP 50458 1277 5 , , , 50458 1277 6 Phar Phar NNP 50458 1277 7 . . . 50458 1277 8 D. D. NNP 50458 1278 1 Recalculated recalculate VBN 50458 1278 2 on on IN 50458 1278 3 the the DT 50458 1278 4 basis basis NN 50458 1278 5 of of IN 50458 1278 6 the the DT 50458 1278 7 latest late JJS 50458 1278 8 atomic atomic JJ 50458 1278 9 weights weight NNS 50458 1278 10 , , , 50458 1278 11 and and CC 50458 1278 12 also also RB 50458 1278 13 greatly greatly RB 50458 1278 14 amplified amplify VBN 50458 1278 15 by by IN 50458 1278 16 the the DT 50458 1278 17 translator translator NN 50458 1278 18 . . . 50458 1279 1 8vo 8vo JJ 50458 1279 2 , , , 50458 1279 3 2 2 CD 50458 1279 4 vols vol NNS 50458 1279 5 . . . 50458 1279 6 , , , 50458 1279 7 upwards upward NNS 50458 1279 8 of of IN 50458 1279 9 2000 2000 CD 50458 1279 10 pages page NNS 50458 1279 11 , , , 50458 1279 12 280 280 CD 50458 1279 13 figures figure NNS 50458 1279 14 . . . 50458 1280 1 Cloth Cloth NNP 50458 1280 2 , , , 50458 1280 3 $ $ $ 50458 1280 4 12.50 12.50 CD 50458 1280 5 . . . 50458 1281 1 = = NFP 50458 1281 2 Techno Techno NNP 50458 1281 3 - - HYPH 50458 1281 4 Chemical Chemical NNP 50458 1281 5 Analysis.= Analysis.= NNP 50458 1281 6 By by IN 50458 1281 7 Dr. Dr. NNP 50458 1281 8 G. G. NNP 50458 1281 9 LUNGE LUNGE NNP 50458 1281 10 , , , 50458 1281 11 Professor Professor NNP 50458 1281 12 at at IN 50458 1281 13 the the DT 50458 1281 14 Eidgenössische Eidgenössische NNP 50458 1281 15 Polytechnische Polytechnische NNP 50458 1281 16 Schule Schule NNP 50458 1281 17 , , , 50458 1281 18 Zurich Zurich NNP 50458 1281 19 . . . 50458 1282 1 Authorized authorized JJ 50458 1282 2 Translation translation NN 50458 1282 3 by by IN 50458 1282 4 Alfred Alfred NNP 50458 1282 5 I. I. NNP 50458 1282 6 Cohn Cohn NNP 50458 1282 7 , , , 50458 1282 8 Phar Phar NNP 50458 1282 9 . . . 50458 1282 10 D. D. NNP 50458 1283 1 12mo 12mo JJ 50458 1283 2 , , , 50458 1283 3 vii vii NN 50458 1283 4 + + SYM 50458 1283 5 136 136 CD 50458 1283 6 pages page NNS 50458 1283 7 , , , 50458 1283 8 16 16 CD 50458 1283 9 figures figure NNS 50458 1283 10 . . . 50458 1284 1 Cloth cloth NN 50458 1284 2 , , , 50458 1284 3 $ $ $ 50458 1284 4 1.00 1.00 CD 50458 1284 5 . . . 50458 1285 1 = = NFP 50458 1285 2 Toxins Toxins NNP 50458 1285 3 and and CC 50458 1285 4 Venoms venom NNS 50458 1285 5 and and CC 50458 1285 6 Their -PRON- PRP$ 50458 1285 7 Antibodies.= antibodies.= NN 50458 1285 8 By by IN 50458 1285 9 EM em NN 50458 1285 10 . . . 50458 1286 1 POZZI POZZI NNP 50458 1286 2 - - HYPH 50458 1286 3 ESCOT ESCOT NNP 50458 1286 4 . . . 50458 1287 1 Authorized authorized JJ 50458 1287 2 Translation translation NN 50458 1287 3 by by IN 50458 1287 4 Alfred Alfred NNP 50458 1287 5 I. I. NNP 50458 1287 6 Cohn Cohn NNP 50458 1287 7 , , , 50458 1287 8 Phar Phar NNP 50458 1287 9 . . . 50458 1287 10 D. D. NNP 50458 1288 1 12mo 12mo JJ 50458 1288 2 , , , 50458 1288 3 vii vii NN 50458 1288 4 + + SYM 50458 1288 5 101 101 CD 50458 1288 6 pages page NNS 50458 1288 7 . . . 50458 1289 1 Cloth cloth NN 50458 1289 2 , , , 50458 1289 3 $ $ $ 50458 1289 4 1.00 1.00 CD 50458 1289 5 , , , 50458 1289 6 _ _ NNP 50458 1289 7 net net NN 50458 1289 8 _ _ NNP 50458 1289 9 . . . 50458 1290 1 Transcriber Transcriber NNP 50458 1290 2 's 's POS 50458 1290 3 Notes Notes NNP 50458 1290 4 Obvious obvious JJ 50458 1290 5 typographical typographical JJ 50458 1290 6 errors error NNS 50458 1290 7 have have VBP 50458 1290 8 been be VBN 50458 1290 9 silently silently RB 50458 1290 10 corrected correct VBN 50458 1290 11 , , , 50458 1290 12 but but CC 50458 1290 13 all all DT 50458 1290 14 other other JJ 50458 1290 15 variations variation NNS 50458 1290 16 in in IN 50458 1290 17 spelling spelling NN 50458 1290 18 , , , 50458 1290 19 punctuation punctuation NN 50458 1290 20 and and CC 50458 1290 21 accents accent NNS 50458 1290 22 are be VBP 50458 1290 23 as as IN 50458 1290 24 in in IN 50458 1290 25 the the DT 50458 1290 26 original original JJ 50458 1290 27 , , , 50458 1290 28 with with IN 50458 1290 29 the the DT 50458 1290 30 exception exception NN 50458 1290 31 of of IN 50458 1290 32 Symptomatology Symptomatology NNP 50458 1290 33 ( ( -LRB- 50458 1290 34 in in IN 50458 1290 35 the the DT 50458 1290 36 contents content NNS 50458 1290 37 list list NN 50458 1290 38 ) ) -RRB- 50458 1290 39 and and CC 50458 1290 40 symptomology symptomology NN 50458 1290 41 ( ( -LRB- 50458 1290 42 in in IN 50458 1290 43 the the DT 50458 1290 44 text text NN 50458 1290 45 ) ) -RRB- 50458 1290 46 which which WDT 50458 1290 47 has have VBZ 50458 1290 48 been be VBN 50458 1290 49 corrected correct VBN 50458 1290 50 to to IN 50458 1290 51 symptomatology symptomatology NN 50458 1290 52 . . . 50458 1291 1 Variations variation NNS 50458 1291 2 between between IN 50458 1291 3 the the DT 50458 1291 4 treatment treatment NN 50458 1291 5 and and CC 50458 1291 6 phrasing phrasing NN 50458 1291 7 of of IN 50458 1291 8 headings heading NNS 50458 1291 9 in in IN 50458 1291 10 the the DT 50458 1291 11 table table NN 50458 1291 12 of of IN 50458 1291 13 contents content NNS 50458 1291 14 and and CC 50458 1291 15 in in IN 50458 1291 16 the the DT 50458 1291 17 text text NN 50458 1291 18 have have VBP 50458 1291 19 not not RB 50458 1291 20 been be VBN 50458 1291 21 changed change VBN 50458 1291 22 . . . 50458 1292 1 Italics italic NNS 50458 1292 2 are be VBP 50458 1292 3 represent represent NN 50458 1292 4 thus thus RB 50458 1292 5 _ _ NNP 50458 1292 6 italic italic JJ 50458 1292 7 _ _ NNP 50458 1292 8 and and CC 50458 1292 9 bold bold JJ 50458 1292 10 thus thus RB 50458 1292 11 = = VBZ 50458 1292 12 bold=. bold=. . 50458 1293 1 Subscripts subscript NNS 50458 1293 2 are be VBP 50458 1293 3 represented represent VBN 50458 1293 4 thus thus RB 50458 1293 5 { { -LRB- 50458 1293 6 2 2 CD 50458 1293 7 } } -RRB- 50458 1293 8 The the DT 50458 1293 9 book book NN 50458 1293 10 begins begin VBZ 50458 1293 11 with with IN 50458 1293 12 a a DT 50458 1293 13 page page NN 50458 1293 14 of of IN 50458 1293 15 adverts advert NNS 50458 1293 16 for for IN 50458 1293 17 works work NNS 50458 1293 18 by by IN 50458 1293 19 the the DT 50458 1293 20 translator translator NN 50458 1293 21 , , , 50458 1293 22 this this DT 50458 1293 23 has have VBZ 50458 1293 24 been be VBN 50458 1293 25 moved move VBN 50458 1293 26 to to IN 50458 1293 27 the the DT 50458 1293 28 end end NN 50458 1293 29 . . .