id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_7t6wuhvmvnee3nndlesmclytvq	Konrad Sarosiek	Hypothyroidism in Pancreatic Cancer: Role of Exogenous Thyroid Hormone in Tumor Invasion—Preliminary Observations	2016	7	.pdf	application/pdf	4496	520	61	Hypothyroidism in Pancreatic Cancer: Role of Exogenous Thyroid Hormone in Tumor Invasion—Preliminary Observations The prevalence of hypothyroidism in our patients with pancreatic cancer was To further understand how thyroid hormone affects pancreatic cancer behavior, functional studies including wound-induced cell migration, proliferation, and invasion were performed on pancreatic cancer cell lines, MiaPaCa-2 and AsPC-1. hypothyroid patients taking exogenous thyroid hormone were more than three times likely to have perineural invasion, and about studies demonstrated that exogenous thyroid hormone treatment increased cell proliferation, migration, and invasion (𝑃 < 0.05). We conclude that exogenous thyroid hormone may contribute to the progression of pancreatic cancer. argue that high levels of thyroid hormones induce cancer cell cancer, hypothyroid patients on thyroid hormone supplementation were found to have significantly (𝑃< 0.05) higher Figure 2: Effects of exogenous thyroid hormone treatment on PDAC cells proliferation, migration, and invasion (𝑃< 0.05). hormones and cancer: clinical studies of hypothyroidism in	./cache/work_7t6wuhvmvnee3nndlesmclytvq.pdf	./txt/work_7t6wuhvmvnee3nndlesmclytvq.txt