id author title date pages extension mime words sentences flesch summary cache txt work_b7h2klfpdjgxrnshzwcumdcsme Koree W. Ahn Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors 2017 .pdf text/html 1138 206 60 [PDF] Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors | Semantic Scholar Corpus ID: 22558737Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors title={Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors}, The homotrimeric HIV-1 envelope glycoprotein (Env) undergoes receptor-triggered structural changes that mediate viral entry through membrane fusion. This process is inhibited by chemokine receptor antagonists (CoRAs) that block Env–receptor interactions and by fusion inhibitors (FIs) that disrupt Env conformational transitions. Sort by Most Influenced Papers Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics View 3 excerpts, references background and methods View 3 excerpts, references background and methods View 3 excerpts, references background and methods By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License ./cache/work_b7h2klfpdjgxrnshzwcumdcsme.pdf ./txt/work_b7h2klfpdjgxrnshzwcumdcsme.txt