id sid tid token lemma pos work_gb5rlsphfjehhkepox5hejbplu 1 1 The the DT work_gb5rlsphfjehhkepox5hejbplu 1 2 Isoform Isoform NNP work_gb5rlsphfjehhkepox5hejbplu 1 3 Specific Specific NNP work_gb5rlsphfjehhkepox5hejbplu 1 4 N N NNP work_gb5rlsphfjehhkepox5hejbplu 1 5 Terminus Terminus NNP work_gb5rlsphfjehhkepox5hejbplu 1 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 1 7 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 1 8 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 1 9 Dispensable dispensable JJ work_gb5rlsphfjehhkepox5hejbplu 1 10 for for IN work_gb5rlsphfjehhkepox5hejbplu 1 11 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 1 12 Induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 1 13 Cytochrome Cytochrome NNP work_gb5rlsphfjehhkepox5hejbplu 1 14 C C NNP work_gb5rlsphfjehhkepox5hejbplu 1 15 Release Release NNP work_gb5rlsphfjehhkepox5hejbplu 1 16 Tuesday Tuesday NNP work_gb5rlsphfjehhkepox5hejbplu 1 17 , , , work_gb5rlsphfjehhkepox5hejbplu 1 18 February February NNP work_gb5rlsphfjehhkepox5hejbplu 1 19 28 28 CD work_gb5rlsphfjehhkepox5hejbplu 1 20 , , , work_gb5rlsphfjehhkepox5hejbplu 1 21 2012 2012 CD work_gb5rlsphfjehhkepox5hejbplu 1 22 437a 437a NNP work_gb5rlsphfjehhkepox5hejbplu 1 23 agent agent NN work_gb5rlsphfjehhkepox5hejbplu 1 24 colchicine colchicine NN work_gb5rlsphfjehhkepox5hejbplu 1 25 that that WDT work_gb5rlsphfjehhkepox5hejbplu 1 26 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 1 27 known know VBN work_gb5rlsphfjehhkepox5hejbplu 1 28 to to TO work_gb5rlsphfjehhkepox5hejbplu 1 29 increase increase VB work_gb5rlsphfjehhkepox5hejbplu 1 30 free free JJ work_gb5rlsphfjehhkepox5hejbplu 1 31 tubulin tubulin NN work_gb5rlsphfjehhkepox5hejbplu 1 32 , , , work_gb5rlsphfjehhkepox5hejbplu 1 33 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 1 34 potential potential NN work_gb5rlsphfjehhkepox5hejbplu 1 35 , , , work_gb5rlsphfjehhkepox5hejbplu 1 36 as as IN work_gb5rlsphfjehhkepox5hejbplu 1 37 measured measure VBN work_gb5rlsphfjehhkepox5hejbplu 1 38 by by IN work_gb5rlsphfjehhkepox5hejbplu 1 39 tetramethylrhodamine tetramethylrhodamine NN work_gb5rlsphfjehhkepox5hejbplu 1 40 methyester methyester NN work_gb5rlsphfjehhkepox5hejbplu 1 41 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 1 42 TMRM TMRM NNP work_gb5rlsphfjehhkepox5hejbplu 1 43 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 1 44 uptake uptake NN work_gb5rlsphfjehhkepox5hejbplu 1 45 , , , work_gb5rlsphfjehhkepox5hejbplu 1 46 decreased decrease VBD work_gb5rlsphfjehhkepox5hejbplu 1 47 . . . work_gb5rlsphfjehhkepox5hejbplu 2 1 Inhibition inhibition NN work_gb5rlsphfjehhkepox5hejbplu 2 2 of of IN work_gb5rlsphfjehhkepox5hejbplu 2 3 PKA PKA NNP work_gb5rlsphfjehhkepox5hejbplu 2 4 activity activity NN work_gb5rlsphfjehhkepox5hejbplu 2 5 with with IN work_gb5rlsphfjehhkepox5hejbplu 2 6 H89 H89 NNP work_gb5rlsphfjehhkepox5hejbplu 2 7 increased increase VBD work_gb5rlsphfjehhkepox5hejbplu 2 8 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 2 9 potential potential NN work_gb5rlsphfjehhkepox5hejbplu 2 10 and and CC work_gb5rlsphfjehhkepox5hejbplu 2 11 , , , work_gb5rlsphfjehhkepox5hejbplu 2 12 fur- fur- DT work_gb5rlsphfjehhkepox5hejbplu 2 13 thermore thermore RB work_gb5rlsphfjehhkepox5hejbplu 2 14 , , , work_gb5rlsphfjehhkepox5hejbplu 2 15 reversed reverse VBD work_gb5rlsphfjehhkepox5hejbplu 2 16 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 2 17 depolarization depolarization NN work_gb5rlsphfjehhkepox5hejbplu 2 18 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 2 19 by by IN work_gb5rlsphfjehhkepox5hejbplu 2 20 colchicine colchicine NN work_gb5rlsphfjehhkepox5hejbplu 2 21 . . . work_gb5rlsphfjehhkepox5hejbplu 3 1 To to TO work_gb5rlsphfjehhkepox5hejbplu 3 2 fur- fur- VB work_gb5rlsphfjehhkepox5hejbplu 3 3 ther ther RB work_gb5rlsphfjehhkepox5hejbplu 3 4 explore explore VB work_gb5rlsphfjehhkepox5hejbplu 3 5 a a DT work_gb5rlsphfjehhkepox5hejbplu 3 6 role role NN work_gb5rlsphfjehhkepox5hejbplu 3 7 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 3 8 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 3 9 tubulin tubulin JJ work_gb5rlsphfjehhkepox5hejbplu 3 10 interaction interaction NN work_gb5rlsphfjehhkepox5hejbplu 3 11 in in IN work_gb5rlsphfjehhkepox5hejbplu 3 12 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 3 13 proliferation proliferation NN work_gb5rlsphfjehhkepox5hejbplu 3 14 and and CC work_gb5rlsphfjehhkepox5hejbplu 3 15 survival survival NN work_gb5rlsphfjehhkepox5hejbplu 3 16 , , , work_gb5rlsphfjehhkepox5hejbplu 3 17 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 3 18 studied study VBD work_gb5rlsphfjehhkepox5hejbplu 3 19 the the DT work_gb5rlsphfjehhkepox5hejbplu 3 20 effect effect NN work_gb5rlsphfjehhkepox5hejbplu 3 21 of of IN work_gb5rlsphfjehhkepox5hejbplu 3 22 erastin erastin NNS work_gb5rlsphfjehhkepox5hejbplu 3 23 , , , work_gb5rlsphfjehhkepox5hejbplu 3 24 the the DT work_gb5rlsphfjehhkepox5hejbplu 3 25 selective selective JJ work_gb5rlsphfjehhkepox5hejbplu 3 26 anti anti JJ work_gb5rlsphfjehhkepox5hejbplu 3 27 - - JJ work_gb5rlsphfjehhkepox5hejbplu 3 28 tumour tumour JJ work_gb5rlsphfjehhkepox5hejbplu 3 29 agent agent NN work_gb5rlsphfjehhkepox5hejbplu 3 30 involved involve VBN work_gb5rlsphfjehhkepox5hejbplu 3 31 in in IN work_gb5rlsphfjehhkepox5hejbplu 3 32 the the DT work_gb5rlsphfjehhkepox5hejbplu 3 33 RAS RAS NNP work_gb5rlsphfjehhkepox5hejbplu 3 34 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 3 35 RAF RAF NNP work_gb5rlsphfjehhkepox5hejbplu 3 36 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 3 37 MEK MEK NNP work_gb5rlsphfjehhkepox5hejbplu 3 38 signalling signalling NN work_gb5rlsphfjehhkepox5hejbplu 3 39 pathway pathway NN work_gb5rlsphfjehhkepox5hejbplu 3 40 , , , work_gb5rlsphfjehhkepox5hejbplu 3 41 on on IN work_gb5rlsphfjehhkepox5hejbplu 3 42 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 3 43 blockage blockage NN work_gb5rlsphfjehhkepox5hejbplu 3 44 by by IN work_gb5rlsphfjehhkepox5hejbplu 3 45 tubulin tubulin NNP work_gb5rlsphfjehhkepox5hejbplu 3 46 . . . work_gb5rlsphfjehhkepox5hejbplu 4 1 We -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 4 2 found find VBD work_gb5rlsphfjehhkepox5hejbplu 4 3 that that IN work_gb5rlsphfjehhkepox5hejbplu 4 4 erastin erastin NNP work_gb5rlsphfjehhkepox5hejbplu 4 5 reverses reverse VBZ work_gb5rlsphfjehhkepox5hejbplu 4 6 tubulin tubulin NN work_gb5rlsphfjehhkepox5hejbplu 4 7 blockage blockage NN work_gb5rlsphfjehhkepox5hejbplu 4 8 of of IN work_gb5rlsphfjehhkepox5hejbplu 4 9 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 4 10 isolated isolate VBN work_gb5rlsphfjehhkepox5hejbplu 4 11 from from IN work_gb5rlsphfjehhkepox5hejbplu 4 12 HepG2 HepG2 NNP work_gb5rlsphfjehhkepox5hejbplu 4 13 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 4 14 , , , work_gb5rlsphfjehhkepox5hejbplu 4 15 pro- pro- NN work_gb5rlsphfjehhkepox5hejbplu 4 16 moting mote VBG work_gb5rlsphfjehhkepox5hejbplu 4 17 the the DT work_gb5rlsphfjehhkepox5hejbplu 4 18 unblocked unblocked JJ work_gb5rlsphfjehhkepox5hejbplu 4 19 state state NN work_gb5rlsphfjehhkepox5hejbplu 4 20 of of IN work_gb5rlsphfjehhkepox5hejbplu 4 21 the the DT work_gb5rlsphfjehhkepox5hejbplu 4 22 channel channel NN work_gb5rlsphfjehhkepox5hejbplu 4 23 . . . work_gb5rlsphfjehhkepox5hejbplu 5 1 Our -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 5 2 findings finding NNS work_gb5rlsphfjehhkepox5hejbplu 5 3 suggest suggest VBP work_gb5rlsphfjehhkepox5hejbplu 5 4 a a DT work_gb5rlsphfjehhkepox5hejbplu 5 5 novel novel JJ work_gb5rlsphfjehhkepox5hejbplu 5 6 func- func- JJ work_gb5rlsphfjehhkepox5hejbplu 5 7 tional tional JJ work_gb5rlsphfjehhkepox5hejbplu 5 8 link link NN work_gb5rlsphfjehhkepox5hejbplu 5 9 between between IN work_gb5rlsphfjehhkepox5hejbplu 5 10 serine serine NNP work_gb5rlsphfjehhkepox5hejbplu 5 11 / / SYM work_gb5rlsphfjehhkepox5hejbplu 5 12 threonine threonine NN work_gb5rlsphfjehhkepox5hejbplu 5 13 kinase kinase NN work_gb5rlsphfjehhkepox5hejbplu 5 14 signalling signal VBG work_gb5rlsphfjehhkepox5hejbplu 5 15 pathways pathway NNS work_gb5rlsphfjehhkepox5hejbplu 5 16 , , , work_gb5rlsphfjehhkepox5hejbplu 5 17 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 5 18 respiration respiration NN work_gb5rlsphfjehhkepox5hejbplu 5 19 , , , work_gb5rlsphfjehhkepox5hejbplu 5 20 and and CC work_gb5rlsphfjehhkepox5hejbplu 5 21 highly highly RB work_gb5rlsphfjehhkepox5hejbplu 5 22 dynamic dynamic JJ work_gb5rlsphfjehhkepox5hejbplu 5 23 microtubule microtubule JJ work_gb5rlsphfjehhkepox5hejbplu 5 24 network network NN work_gb5rlsphfjehhkepox5hejbplu 5 25 which which WDT work_gb5rlsphfjehhkepox5hejbplu 5 26 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 5 27 characteristic characteristic JJ work_gb5rlsphfjehhkepox5hejbplu 5 28 of of IN work_gb5rlsphfjehhkepox5hejbplu 5 29 carcinogenesis carcinogenesis NN work_gb5rlsphfjehhkepox5hejbplu 5 30 and and CC work_gb5rlsphfjehhkepox5hejbplu 5 31 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 5 32 proliferation proliferation NN work_gb5rlsphfjehhkepox5hejbplu 5 33 . . . work_gb5rlsphfjehhkepox5hejbplu 6 1 2216-Plat 2216-plat CD work_gb5rlsphfjehhkepox5hejbplu 6 2 The the DT work_gb5rlsphfjehhkepox5hejbplu 6 3 Isoform Isoform NNP work_gb5rlsphfjehhkepox5hejbplu 6 4 Specific Specific NNP work_gb5rlsphfjehhkepox5hejbplu 6 5 N N NNP work_gb5rlsphfjehhkepox5hejbplu 6 6 Terminus Terminus NNP work_gb5rlsphfjehhkepox5hejbplu 6 7 of of IN work_gb5rlsphfjehhkepox5hejbplu 6 8 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 6 9 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 6 10 Dispensable dispensable JJ work_gb5rlsphfjehhkepox5hejbplu 6 11 for for IN work_gb5rlsphfjehhkepox5hejbplu 6 12 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 6 13 Induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 6 14 Cytochrome Cytochrome NNP work_gb5rlsphfjehhkepox5hejbplu 6 15 C c NN work_gb5rlsphfjehhkepox5hejbplu 6 16 Release Release NNP work_gb5rlsphfjehhkepox5hejbplu 6 17 Shamim Shamim NNP work_gb5rlsphfjehhkepox5hejbplu 6 18 Naghdi1 Naghdi1 NNP work_gb5rlsphfjehhkepox5hejbplu 6 19 , , , work_gb5rlsphfjehhkepox5hejbplu 6 20 Peter Peter NNP work_gb5rlsphfjehhkepox5hejbplu 6 21 Varnai2 Varnai2 NNP work_gb5rlsphfjehhkepox5hejbplu 6 22 , , , work_gb5rlsphfjehhkepox5hejbplu 6 23 Laszlo Laszlo NNP work_gb5rlsphfjehhkepox5hejbplu 6 24 Hunyady2 Hunyady2 NNP work_gb5rlsphfjehhkepox5hejbplu 6 25 , , , work_gb5rlsphfjehhkepox5hejbplu 6 26 Gyorgy Gyorgy NNP work_gb5rlsphfjehhkepox5hejbplu 6 27 Hajnoczky1 Hajnoczky1 NNP work_gb5rlsphfjehhkepox5hejbplu 6 28 . . . work_gb5rlsphfjehhkepox5hejbplu 7 1 1Thomas 1Thomas NNP work_gb5rlsphfjehhkepox5hejbplu 7 2 Jefferson Jefferson NNP work_gb5rlsphfjehhkepox5hejbplu 7 3 University University NNP work_gb5rlsphfjehhkepox5hejbplu 7 4 , , , work_gb5rlsphfjehhkepox5hejbplu 7 5 Department Department NNP work_gb5rlsphfjehhkepox5hejbplu 7 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 7 7 Pathology Pathology NNP work_gb5rlsphfjehhkepox5hejbplu 7 8 Anatomy Anatomy NNP work_gb5rlsphfjehhkepox5hejbplu 7 9 and and CC work_gb5rlsphfjehhkepox5hejbplu 7 10 Cell Cell NNP work_gb5rlsphfjehhkepox5hejbplu 7 11 Biology Biology NNP work_gb5rlsphfjehhkepox5hejbplu 7 12 , , , work_gb5rlsphfjehhkepox5hejbplu 7 13 Philadelphia Philadelphia NNP work_gb5rlsphfjehhkepox5hejbplu 7 14 , , , work_gb5rlsphfjehhkepox5hejbplu 7 15 PA PA NNP work_gb5rlsphfjehhkepox5hejbplu 7 16 , , , work_gb5rlsphfjehhkepox5hejbplu 7 17 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 7 18 , , , work_gb5rlsphfjehhkepox5hejbplu 7 19 2 2 CD work_gb5rlsphfjehhkepox5hejbplu 7 20 Semmelweis Semmelweis NNP work_gb5rlsphfjehhkepox5hejbplu 7 21 University University NNP work_gb5rlsphfjehhkepox5hejbplu 7 22 , , , work_gb5rlsphfjehhkepox5hejbplu 7 23 Faculty Faculty NNP work_gb5rlsphfjehhkepox5hejbplu 7 24 of of IN work_gb5rlsphfjehhkepox5hejbplu 7 25 Medicine Medicine NNP work_gb5rlsphfjehhkepox5hejbplu 7 26 , , , work_gb5rlsphfjehhkepox5hejbplu 7 27 Department Department NNP work_gb5rlsphfjehhkepox5hejbplu 7 28 of of IN work_gb5rlsphfjehhkepox5hejbplu 7 29 Physiology Physiology NNP work_gb5rlsphfjehhkepox5hejbplu 7 30 , , , work_gb5rlsphfjehhkepox5hejbplu 7 31 Budapest Budapest NNP work_gb5rlsphfjehhkepox5hejbplu 7 32 , , , work_gb5rlsphfjehhkepox5hejbplu 7 33 Hungary Hungary NNP work_gb5rlsphfjehhkepox5hejbplu 7 34 . . . work_gb5rlsphfjehhkepox5hejbplu 8 1 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 8 2 proteins protein NNS work_gb5rlsphfjehhkepox5hejbplu 8 3 represent represent VBP work_gb5rlsphfjehhkepox5hejbplu 8 4 a a DT work_gb5rlsphfjehhkepox5hejbplu 8 5 main main JJ work_gb5rlsphfjehhkepox5hejbplu 8 6 component component NN work_gb5rlsphfjehhkepox5hejbplu 8 7 of of IN work_gb5rlsphfjehhkepox5hejbplu 8 8 the the DT work_gb5rlsphfjehhkepox5hejbplu 8 9 outer outer NNP work_gb5rlsphfjehhkepox5hejbplu 8 10 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 8 11 mem- mem- NNP work_gb5rlsphfjehhkepox5hejbplu 8 12 brane brane NNP work_gb5rlsphfjehhkepox5hejbplu 8 13 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 8 14 OMM OMM NNP work_gb5rlsphfjehhkepox5hejbplu 8 15 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 8 16 . . . work_gb5rlsphfjehhkepox5hejbplu 9 1 The the DT work_gb5rlsphfjehhkepox5hejbplu 9 2 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 9 3 family family NN work_gb5rlsphfjehhkepox5hejbplu 9 4 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 9 5 composed compose VBN work_gb5rlsphfjehhkepox5hejbplu 9 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 9 7 3 3 CD work_gb5rlsphfjehhkepox5hejbplu 9 8 isoforms isoform NNS work_gb5rlsphfjehhkepox5hejbplu 9 9 with with IN work_gb5rlsphfjehhkepox5hejbplu 9 10 more more JJR work_gb5rlsphfjehhkepox5hejbplu 9 11 than than IN work_gb5rlsphfjehhkepox5hejbplu 9 12 70 70 CD work_gb5rlsphfjehhkepox5hejbplu 9 13 percent percent NN work_gb5rlsphfjehhkepox5hejbplu 9 14 similarity similarity NN work_gb5rlsphfjehhkepox5hejbplu 9 15 . . . work_gb5rlsphfjehhkepox5hejbplu 10 1 Although although IN work_gb5rlsphfjehhkepox5hejbplu 10 2 their -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 10 3 primary primary JJ work_gb5rlsphfjehhkepox5hejbplu 10 4 role role NN work_gb5rlsphfjehhkepox5hejbplu 10 5 was be VBD work_gb5rlsphfjehhkepox5hejbplu 10 6 known know VBN work_gb5rlsphfjehhkepox5hejbplu 10 7 to to TO work_gb5rlsphfjehhkepox5hejbplu 10 8 be be VB work_gb5rlsphfjehhkepox5hejbplu 10 9 in in IN work_gb5rlsphfjehhkepox5hejbplu 10 10 ion ion NN work_gb5rlsphfjehhkepox5hejbplu 10 11 and and CC work_gb5rlsphfjehhkepox5hejbplu 10 12 me- me- XX work_gb5rlsphfjehhkepox5hejbplu 10 13 tabolite tabolite NN work_gb5rlsphfjehhkepox5hejbplu 10 14 transport transport NN work_gb5rlsphfjehhkepox5hejbplu 10 15 between between IN work_gb5rlsphfjehhkepox5hejbplu 10 16 mitochnodria mitochnodria NNP work_gb5rlsphfjehhkepox5hejbplu 10 17 and and CC work_gb5rlsphfjehhkepox5hejbplu 10 18 cytosol cytosol NNP work_gb5rlsphfjehhkepox5hejbplu 10 19 , , , work_gb5rlsphfjehhkepox5hejbplu 10 20 it -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 10 21 has have VBZ work_gb5rlsphfjehhkepox5hejbplu 10 22 been be VBN work_gb5rlsphfjehhkepox5hejbplu 10 23 discovered discover VBN work_gb5rlsphfjehhkepox5hejbplu 10 24 that that IN work_gb5rlsphfjehhkepox5hejbplu 10 25 VDACs vdac NNS work_gb5rlsphfjehhkepox5hejbplu 10 26 are be VBP work_gb5rlsphfjehhkepox5hejbplu 10 27 involved involve VBN work_gb5rlsphfjehhkepox5hejbplu 10 28 in in IN work_gb5rlsphfjehhkepox5hejbplu 10 29 apoptotic apoptotic JJ work_gb5rlsphfjehhkepox5hejbplu 10 30 pathways pathway NNS work_gb5rlsphfjehhkepox5hejbplu 10 31 . . . work_gb5rlsphfjehhkepox5hejbplu 11 1 We -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 11 2 have have VBP work_gb5rlsphfjehhkepox5hejbplu 11 3 recently recently RB work_gb5rlsphfjehhkepox5hejbplu 11 4 found find VBN work_gb5rlsphfjehhkepox5hejbplu 11 5 that that IN work_gb5rlsphfjehhkepox5hejbplu 11 6 spe- spe- XX work_gb5rlsphfjehhkepox5hejbplu 11 7 cifically cifically RB work_gb5rlsphfjehhkepox5hejbplu 11 8 the the DT work_gb5rlsphfjehhkepox5hejbplu 11 9 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 11 10 isoform isoform NN work_gb5rlsphfjehhkepox5hejbplu 11 11 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 11 12 needed need VBN work_gb5rlsphfjehhkepox5hejbplu 11 13 for for IN work_gb5rlsphfjehhkepox5hejbplu 11 14 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 11 15 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 11 16 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 11 17 cytochrome cytochrome NN work_gb5rlsphfjehhkepox5hejbplu 11 18 c c NN work_gb5rlsphfjehhkepox5hejbplu 11 19 release release NN work_gb5rlsphfjehhkepox5hejbplu 11 20 , , , work_gb5rlsphfjehhkepox5hejbplu 11 21 due due IN work_gb5rlsphfjehhkepox5hejbplu 11 22 to to IN work_gb5rlsphfjehhkepox5hejbplu 11 23 its -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 11 24 role role NN work_gb5rlsphfjehhkepox5hejbplu 11 25 in in IN work_gb5rlsphfjehhkepox5hejbplu 11 26 supporting support VBG work_gb5rlsphfjehhkepox5hejbplu 11 27 Bak bak PRP$ work_gb5rlsphfjehhkepox5hejbplu 11 28 insertion insertion NN work_gb5rlsphfjehhkepox5hejbplu 11 29 to to IN work_gb5rlsphfjehhkepox5hejbplu 11 30 the the DT work_gb5rlsphfjehhkepox5hejbplu 11 31 OMM OMM NNP work_gb5rlsphfjehhkepox5hejbplu 11 32 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 11 33 Roy Roy NNP work_gb5rlsphfjehhkepox5hejbplu 11 34 et et NNP work_gb5rlsphfjehhkepox5hejbplu 11 35 al.2009 al.2009 FW work_gb5rlsphfjehhkepox5hejbplu 11 36 . . . work_gb5rlsphfjehhkepox5hejbplu 12 1 EMBO EMBO NNP work_gb5rlsphfjehhkepox5hejbplu 12 2 Rep.10:1341 Rep.10:1341 NNPS work_gb5rlsphfjehhkepox5hejbplu 12 3 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 12 4 7 7 CD work_gb5rlsphfjehhkepox5hejbplu 12 5 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 12 6 . . . work_gb5rlsphfjehhkepox5hejbplu 13 1 Sequence sequence NN work_gb5rlsphfjehhkepox5hejbplu 13 2 analysis analysis NN work_gb5rlsphfjehhkepox5hejbplu 13 3 of of IN work_gb5rlsphfjehhkepox5hejbplu 13 4 the the DT work_gb5rlsphfjehhkepox5hejbplu 13 5 mammalian mammalian JJ work_gb5rlsphfjehhkepox5hejbplu 13 6 VDAC VDAC NNP work_gb5rlsphfjehhkepox5hejbplu 13 7 isoforms isoform NNS work_gb5rlsphfjehhkepox5hejbplu 13 8 shows show VBZ work_gb5rlsphfjehhkepox5hejbplu 13 9 a a DT work_gb5rlsphfjehhkepox5hejbplu 13 10 unique unique JJ work_gb5rlsphfjehhkepox5hejbplu 13 11 N n NN work_gb5rlsphfjehhkepox5hejbplu 13 12 terminal terminal JJ work_gb5rlsphfjehhkepox5hejbplu 13 13 end end NN work_gb5rlsphfjehhkepox5hejbplu 13 14 in in IN work_gb5rlsphfjehhkepox5hejbplu 13 15 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 13 16 , , , work_gb5rlsphfjehhkepox5hejbplu 13 17 which which WDT work_gb5rlsphfjehhkepox5hejbplu 13 18 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 13 19 likely likely JJ work_gb5rlsphfjehhkepox5hejbplu 13 20 to to TO work_gb5rlsphfjehhkepox5hejbplu 13 21 be be VB work_gb5rlsphfjehhkepox5hejbplu 13 22 exposed expose VBN work_gb5rlsphfjehhkepox5hejbplu 13 23 to to IN work_gb5rlsphfjehhkepox5hejbplu 13 24 the the DT work_gb5rlsphfjehhkepox5hejbplu 13 25 cyto- cyto- JJ work_gb5rlsphfjehhkepox5hejbplu 13 26 plasm plasm NN work_gb5rlsphfjehhkepox5hejbplu 13 27 . . . work_gb5rlsphfjehhkepox5hejbplu 14 1 To to TO work_gb5rlsphfjehhkepox5hejbplu 14 2 test test VB work_gb5rlsphfjehhkepox5hejbplu 14 3 the the DT work_gb5rlsphfjehhkepox5hejbplu 14 4 functional functional JJ work_gb5rlsphfjehhkepox5hejbplu 14 5 significance significance NN work_gb5rlsphfjehhkepox5hejbplu 14 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 14 7 this this DT work_gb5rlsphfjehhkepox5hejbplu 14 8 N n CD work_gb5rlsphfjehhkepox5hejbplu 14 9 terminus terminus NN work_gb5rlsphfjehhkepox5hejbplu 14 10 , , , work_gb5rlsphfjehhkepox5hejbplu 14 11 the the DT work_gb5rlsphfjehhkepox5hejbplu 14 12 first first JJ work_gb5rlsphfjehhkepox5hejbplu 14 13 12 12 CD work_gb5rlsphfjehhkepox5hejbplu 14 14 amino amino JJ work_gb5rlsphfjehhkepox5hejbplu 14 15 acids acid NNS work_gb5rlsphfjehhkepox5hejbplu 14 16 were be VBD work_gb5rlsphfjehhkepox5hejbplu 14 17 removed remove VBN work_gb5rlsphfjehhkepox5hejbplu 14 18 from from IN work_gb5rlsphfjehhkepox5hejbplu 14 19 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 14 20 or or CC work_gb5rlsphfjehhkepox5hejbplu 14 21 were be VBD work_gb5rlsphfjehhkepox5hejbplu 14 22 added add VBN work_gb5rlsphfjehhkepox5hejbplu 14 23 to to IN work_gb5rlsphfjehhkepox5hejbplu 14 24 VDAC1 VDAC1 NNP work_gb5rlsphfjehhkepox5hejbplu 14 25 . . . work_gb5rlsphfjehhkepox5hejbplu 15 1 VDAC2-/- VDAC2-/- NNP work_gb5rlsphfjehhkepox5hejbplu 15 2 MEF MEF NNP work_gb5rlsphfjehhkepox5hejbplu 15 3 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 15 4 that that WDT work_gb5rlsphfjehhkepox5hejbplu 15 5 are be VBP work_gb5rlsphfjehhkepox5hejbplu 15 6 resistant resistant JJ work_gb5rlsphfjehhkepox5hejbplu 15 7 to to IN work_gb5rlsphfjehhkepox5hejbplu 15 8 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 15 9 , , , work_gb5rlsphfjehhkepox5hejbplu 15 10 were be VBD work_gb5rlsphfjehhkepox5hejbplu 15 11 rescued rescue VBN work_gb5rlsphfjehhkepox5hejbplu 15 12 with with IN work_gb5rlsphfjehhkepox5hejbplu 15 13 these these DT work_gb5rlsphfjehhkepox5hejbplu 15 14 constructs construct NNS work_gb5rlsphfjehhkepox5hejbplu 15 15 and and CC work_gb5rlsphfjehhkepox5hejbplu 15 16 cyto- cyto- NNS work_gb5rlsphfjehhkepox5hejbplu 15 17 chrome chrome NNP work_gb5rlsphfjehhkepox5hejbplu 15 18 c c NNP work_gb5rlsphfjehhkepox5hejbplu 15 19 release release NN work_gb5rlsphfjehhkepox5hejbplu 15 20 was be VBD work_gb5rlsphfjehhkepox5hejbplu 15 21 monitored monitor VBN work_gb5rlsphfjehhkepox5hejbplu 15 22 in in IN work_gb5rlsphfjehhkepox5hejbplu 15 23 permeabilized permeabilized JJ work_gb5rlsphfjehhkepox5hejbplu 15 24 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 15 25 by by IN work_gb5rlsphfjehhkepox5hejbplu 15 26 single single JJ work_gb5rlsphfjehhkepox5hejbplu 15 27 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 15 28 imaging imaging NN work_gb5rlsphfjehhkepox5hejbplu 15 29 and and CC work_gb5rlsphfjehhkepox5hejbplu 15 30 immunoblotting immunoblotte VBG work_gb5rlsphfjehhkepox5hejbplu 15 31 . . . work_gb5rlsphfjehhkepox5hejbplu 16 1 These these DT work_gb5rlsphfjehhkepox5hejbplu 16 2 studies study NNS work_gb5rlsphfjehhkepox5hejbplu 16 3 revealed reveal VBD work_gb5rlsphfjehhkepox5hejbplu 16 4 that that IN work_gb5rlsphfjehhkepox5hejbplu 16 5 cytochrome cytochrome NN work_gb5rlsphfjehhkepox5hejbplu 16 6 c c NN work_gb5rlsphfjehhkepox5hejbplu 16 7 release release NN work_gb5rlsphfjehhkepox5hejbplu 16 8 upon upon IN work_gb5rlsphfjehhkepox5hejbplu 16 9 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 16 10 application application NN work_gb5rlsphfjehhkepox5hejbplu 16 11 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 16 12 effectively effectively RB work_gb5rlsphfjehhkepox5hejbplu 16 13 supported support VBN work_gb5rlsphfjehhkepox5hejbplu 16 14 by by IN work_gb5rlsphfjehhkepox5hejbplu 16 15 both both DT work_gb5rlsphfjehhkepox5hejbplu 16 16 full full JJ work_gb5rlsphfjehhkepox5hejbplu 16 17 length length NN work_gb5rlsphfjehhkepox5hejbplu 16 18 VDAC2 vdac2 NN work_gb5rlsphfjehhkepox5hejbplu 16 19 and and CC work_gb5rlsphfjehhkepox5hejbplu 16 20 the the DT work_gb5rlsphfjehhkepox5hejbplu 16 21 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 16 22 N n CD work_gb5rlsphfjehhkepox5hejbplu 16 23 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 16 24 terminal terminal NN work_gb5rlsphfjehhkepox5hejbplu 16 25 deletion deletion NN work_gb5rlsphfjehhkepox5hejbplu 16 26 mutant mutant NN work_gb5rlsphfjehhkepox5hejbplu 16 27 . . . work_gb5rlsphfjehhkepox5hejbplu 17 1 Furthermore furthermore RB work_gb5rlsphfjehhkepox5hejbplu 17 2 , , , work_gb5rlsphfjehhkepox5hejbplu 17 3 VDAC1 VDAC1 NNP work_gb5rlsphfjehhkepox5hejbplu 17 4 extended extend VBN work_gb5rlsphfjehhkepox5hejbplu 17 5 by by IN work_gb5rlsphfjehhkepox5hejbplu 17 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 17 7 N n NN work_gb5rlsphfjehhkepox5hejbplu 17 8 terminus terminus NN work_gb5rlsphfjehhkepox5hejbplu 17 9 of of IN work_gb5rlsphfjehhkepox5hejbplu 17 10 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 17 11 failed fail VBD work_gb5rlsphfjehhkepox5hejbplu 17 12 to to TO work_gb5rlsphfjehhkepox5hejbplu 17 13 restore restore VB work_gb5rlsphfjehhkepox5hejbplu 17 14 cytochrome cytochrome DT work_gb5rlsphfjehhkepox5hejbplu 17 15 c c NN work_gb5rlsphfjehhkepox5hejbplu 17 16 release release NN work_gb5rlsphfjehhkepox5hejbplu 17 17 in in IN work_gb5rlsphfjehhkepox5hejbplu 17 18 VDAC2-/- VDAC2-/- NNP work_gb5rlsphfjehhkepox5hejbplu 17 19 MEFs MEFs NNPS work_gb5rlsphfjehhkepox5hejbplu 17 20 . . . work_gb5rlsphfjehhkepox5hejbplu 18 1 Thus thus RB work_gb5rlsphfjehhkepox5hejbplu 18 2 the the DT work_gb5rlsphfjehhkepox5hejbplu 18 3 N n CD work_gb5rlsphfjehhkepox5hejbplu 18 4 terminus terminus NN work_gb5rlsphfjehhkepox5hejbplu 18 5 of of IN work_gb5rlsphfjehhkepox5hejbplu 18 6 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 18 7 seems seem VBZ work_gb5rlsphfjehhkepox5hejbplu 18 8 to to TO work_gb5rlsphfjehhkepox5hejbplu 18 9 be be VB work_gb5rlsphfjehhkepox5hejbplu 18 10 dispensible dispensible JJ work_gb5rlsphfjehhkepox5hejbplu 18 11 for for IN work_gb5rlsphfjehhkepox5hejbplu 18 12 tBid- tbid- CD work_gb5rlsphfjehhkepox5hejbplu 18 13 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 18 14 OMM OMM NNP work_gb5rlsphfjehhkepox5hejbplu 18 15 permeabilization permeabilization NN work_gb5rlsphfjehhkepox5hejbplu 18 16 . . . work_gb5rlsphfjehhkepox5hejbplu 19 1 Currently currently RB work_gb5rlsphfjehhkepox5hejbplu 19 2 , , , work_gb5rlsphfjehhkepox5hejbplu 19 3 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 19 4 are be VBP work_gb5rlsphfjehhkepox5hejbplu 19 5 designing design VBG work_gb5rlsphfjehhkepox5hejbplu 19 6 different different JJ work_gb5rlsphfjehhkepox5hejbplu 19 7 muta- muta- JJ work_gb5rlsphfjehhkepox5hejbplu 19 8 tions tion NNS work_gb5rlsphfjehhkepox5hejbplu 19 9 which which WDT work_gb5rlsphfjehhkepox5hejbplu 19 10 target target VBP work_gb5rlsphfjehhkepox5hejbplu 19 11 some some DT work_gb5rlsphfjehhkepox5hejbplu 19 12 addititional addititional JJ work_gb5rlsphfjehhkepox5hejbplu 19 13 unique unique JJ work_gb5rlsphfjehhkepox5hejbplu 19 14 sequences sequence NNS work_gb5rlsphfjehhkepox5hejbplu 19 15 in in IN work_gb5rlsphfjehhkepox5hejbplu 19 16 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 19 17 to to TO work_gb5rlsphfjehhkepox5hejbplu 19 18 find find VB work_gb5rlsphfjehhkepox5hejbplu 19 19 the the DT work_gb5rlsphfjehhkepox5hejbplu 19 20 specific specific JJ work_gb5rlsphfjehhkepox5hejbplu 19 21 domain domain NN work_gb5rlsphfjehhkepox5hejbplu 19 22 that that WDT work_gb5rlsphfjehhkepox5hejbplu 19 23 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 19 24 essential essential JJ work_gb5rlsphfjehhkepox5hejbplu 19 25 for for IN work_gb5rlsphfjehhkepox5hejbplu 19 26 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 19 27 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 19 28 cytochrome cytochrome DT work_gb5rlsphfjehhkepox5hejbplu 19 29 c c NN work_gb5rlsphfjehhkepox5hejbplu 19 30 release release NN work_gb5rlsphfjehhkepox5hejbplu 19 31 . . . work_gb5rlsphfjehhkepox5hejbplu 20 1 2217-Plat 2217-plat CD work_gb5rlsphfjehhkepox5hejbplu 20 2 Patch Patch NNP work_gb5rlsphfjehhkepox5hejbplu 20 3 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 20 4 Clamp Clamp NNP work_gb5rlsphfjehhkepox5hejbplu 20 5 Analysis Analysis NNP work_gb5rlsphfjehhkepox5hejbplu 20 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 20 7 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 20 8 Ca2D Ca2D NNP work_gb5rlsphfjehhkepox5hejbplu 20 9 Uniporter Uniporter NNP work_gb5rlsphfjehhkepox5hejbplu 20 10 in in IN work_gb5rlsphfjehhkepox5hejbplu 20 11 Different Different NNP work_gb5rlsphfjehhkepox5hejbplu 20 12 Tissues Tissues NNP work_gb5rlsphfjehhkepox5hejbplu 20 13 Francesca Francesca NNP work_gb5rlsphfjehhkepox5hejbplu 20 14 Fieni Fieni NNP work_gb5rlsphfjehhkepox5hejbplu 20 15 , , , work_gb5rlsphfjehhkepox5hejbplu 20 16 Yuriy Yuriy NNP work_gb5rlsphfjehhkepox5hejbplu 20 17 Kirichok Kirichok NNP work_gb5rlsphfjehhkepox5hejbplu 20 18 . . . work_gb5rlsphfjehhkepox5hejbplu 21 1 UCSF UCSF NNP work_gb5rlsphfjehhkepox5hejbplu 21 2 , , , work_gb5rlsphfjehhkepox5hejbplu 21 3 San San NNP work_gb5rlsphfjehhkepox5hejbplu 21 4 Francisco Francisco NNP work_gb5rlsphfjehhkepox5hejbplu 21 5 , , , work_gb5rlsphfjehhkepox5hejbplu 21 6 CA CA NNP work_gb5rlsphfjehhkepox5hejbplu 21 7 , , , work_gb5rlsphfjehhkepox5hejbplu 21 8 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 21 9 . . . work_gb5rlsphfjehhkepox5hejbplu 22 1 The the DT work_gb5rlsphfjehhkepox5hejbplu 22 2 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 22 3 Ca2þ ca2þ NN work_gb5rlsphfjehhkepox5hejbplu 22 4 uptake uptake NN work_gb5rlsphfjehhkepox5hejbplu 22 5 has have VBZ work_gb5rlsphfjehhkepox5hejbplu 22 6 been be VBN work_gb5rlsphfjehhkepox5hejbplu 22 7 recognized recognize VBN work_gb5rlsphfjehhkepox5hejbplu 22 8 as as IN work_gb5rlsphfjehhkepox5hejbplu 22 9 a a DT work_gb5rlsphfjehhkepox5hejbplu 22 10 central central JJ work_gb5rlsphfjehhkepox5hejbplu 22 11 player player NN work_gb5rlsphfjehhkepox5hejbplu 22 12 in in IN work_gb5rlsphfjehhkepox5hejbplu 22 13 cel- cel- NNP work_gb5rlsphfjehhkepox5hejbplu 22 14 lular lular NNP work_gb5rlsphfjehhkepox5hejbplu 22 15 pathophysiology pathophysiology NN work_gb5rlsphfjehhkepox5hejbplu 22 16 for for IN work_gb5rlsphfjehhkepox5hejbplu 22 17 decades decade NNS work_gb5rlsphfjehhkepox5hejbplu 22 18 . . . work_gb5rlsphfjehhkepox5hejbplu 23 1 Pathways pathway NNS work_gb5rlsphfjehhkepox5hejbplu 23 2 of of IN work_gb5rlsphfjehhkepox5hejbplu 23 3 Ca2þ ca2þ NN work_gb5rlsphfjehhkepox5hejbplu 23 4 transport transport NN work_gb5rlsphfjehhkepox5hejbplu 23 5 across across IN work_gb5rlsphfjehhkepox5hejbplu 23 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 23 7 inner inner JJ work_gb5rlsphfjehhkepox5hejbplu 23 8 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 23 9 membrane membrane NN work_gb5rlsphfjehhkepox5hejbplu 23 10 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 23 11 IMM IMM NNP work_gb5rlsphfjehhkepox5hejbplu 23 12 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 23 13 were be VBD work_gb5rlsphfjehhkepox5hejbplu 23 14 investigated investigate VBN work_gb5rlsphfjehhkepox5hejbplu 23 15 indirectly indirectly RB work_gb5rlsphfjehhkepox5hejbplu 23 16 with with IN work_gb5rlsphfjehhkepox5hejbplu 23 17 biochemical biochemical JJ work_gb5rlsphfjehhkepox5hejbplu 23 18 techniques technique NNS work_gb5rlsphfjehhkepox5hejbplu 23 19 and and CC work_gb5rlsphfjehhkepox5hejbplu 23 20 most most RBS work_gb5rlsphfjehhkepox5hejbplu 23 21 recently recently RB work_gb5rlsphfjehhkepox5hejbplu 23 22 by by IN work_gb5rlsphfjehhkepox5hejbplu 23 23 applying apply VBG work_gb5rlsphfjehhkepox5hejbplu 23 24 the the DT work_gb5rlsphfjehhkepox5hejbplu 23 25 patch patch NN work_gb5rlsphfjehhkepox5hejbplu 23 26 clamp clamp NN work_gb5rlsphfjehhkepox5hejbplu 23 27 technique technique NN work_gb5rlsphfjehhkepox5hejbplu 23 28 to to TO work_gb5rlsphfjehhkepox5hejbplu 23 29 mito- mito- VB work_gb5rlsphfjehhkepox5hejbplu 23 30 plasts plast NNS work_gb5rlsphfjehhkepox5hejbplu 23 31 isolated isolate VBN work_gb5rlsphfjehhkepox5hejbplu 23 32 from from IN work_gb5rlsphfjehhkepox5hejbplu 23 33 mammalian mammalian JJ work_gb5rlsphfjehhkepox5hejbplu 23 34 systems system NNS work_gb5rlsphfjehhkepox5hejbplu 23 35 . . . work_gb5rlsphfjehhkepox5hejbplu 24 1 Patch patch JJ work_gb5rlsphfjehhkepox5hejbplu 24 2 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 24 3 clamp clamp NN work_gb5rlsphfjehhkepox5hejbplu 24 4 recording recording NN work_gb5rlsphfjehhkepox5hejbplu 24 5 of of IN work_gb5rlsphfjehhkepox5hejbplu 24 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 24 7 IMM IMM NNP work_gb5rlsphfjehhkepox5hejbplu 24 8 have have VBP work_gb5rlsphfjehhkepox5hejbplu 24 9 proved prove VBN work_gb5rlsphfjehhkepox5hejbplu 24 10 to to TO work_gb5rlsphfjehhkepox5hejbplu 24 11 provide provide VB work_gb5rlsphfjehhkepox5hejbplu 24 12 an an DT work_gb5rlsphfjehhkepox5hejbplu 24 13 unambiguous unambiguous JJ work_gb5rlsphfjehhkepox5hejbplu 24 14 picture picture NN work_gb5rlsphfjehhkepox5hejbplu 24 15 of of IN work_gb5rlsphfjehhkepox5hejbplu 24 16 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 24 17 Ca2þ ca2þ NN work_gb5rlsphfjehhkepox5hejbplu 24 18 uptake uptake NN work_gb5rlsphfjehhkepox5hejbplu 24 19 under under IN work_gb5rlsphfjehhkepox5hejbplu 24 20 strictly strictly RB work_gb5rlsphfjehhkepox5hejbplu 24 21 controlled control VBN work_gb5rlsphfjehhkepox5hejbplu 24 22 conditions condition NNS work_gb5rlsphfjehhkepox5hejbplu 24 23 . . . work_gb5rlsphfjehhkepox5hejbplu 25 1 In in IN work_gb5rlsphfjehhkepox5hejbplu 25 2 this this DT work_gb5rlsphfjehhkepox5hejbplu 25 3 study study NN work_gb5rlsphfjehhkepox5hejbplu 25 4 , , , work_gb5rlsphfjehhkepox5hejbplu 25 5 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 25 6 evaluated evaluate VBD work_gb5rlsphfjehhkepox5hejbplu 25 7 and and CC work_gb5rlsphfjehhkepox5hejbplu 25 8 compared compare VBD work_gb5rlsphfjehhkepox5hejbplu 25 9 the the DT work_gb5rlsphfjehhkepox5hejbplu 25 10 biophysical biophysical JJ work_gb5rlsphfjehhkepox5hejbplu 25 11 properties property NNS work_gb5rlsphfjehhkepox5hejbplu 25 12 of of IN work_gb5rlsphfjehhkepox5hejbplu 25 13 mito- mito- NNP work_gb5rlsphfjehhkepox5hejbplu 25 14 chondrial chondrial NNP work_gb5rlsphfjehhkepox5hejbplu 25 15 Ca2þ Ca2þ NNP work_gb5rlsphfjehhkepox5hejbplu 25 16 uptake uptake NN work_gb5rlsphfjehhkepox5hejbplu 25 17 in in IN work_gb5rlsphfjehhkepox5hejbplu 25 18 different different JJ work_gb5rlsphfjehhkepox5hejbplu 25 19 mouse mouse NN work_gb5rlsphfjehhkepox5hejbplu 25 20 tissues tissue NNS work_gb5rlsphfjehhkepox5hejbplu 25 21 . . . work_gb5rlsphfjehhkepox5hejbplu 26 1 Freshly freshly RB work_gb5rlsphfjehhkepox5hejbplu 26 2 isolated isolated JJ work_gb5rlsphfjehhkepox5hejbplu 26 3 mitoplasts mitoplast NNS work_gb5rlsphfjehhkepox5hejbplu 26 4 from from IN work_gb5rlsphfjehhkepox5hejbplu 26 5 mouse mouse NN work_gb5rlsphfjehhkepox5hejbplu 26 6 heart heart NN work_gb5rlsphfjehhkepox5hejbplu 26 7 , , , work_gb5rlsphfjehhkepox5hejbplu 26 8 skeletal skeletal JJ work_gb5rlsphfjehhkepox5hejbplu 26 9 muscle muscle NN work_gb5rlsphfjehhkepox5hejbplu 26 10 , , , work_gb5rlsphfjehhkepox5hejbplu 26 11 liver liver NN work_gb5rlsphfjehhkepox5hejbplu 26 12 , , , work_gb5rlsphfjehhkepox5hejbplu 26 13 kidney kidney NN work_gb5rlsphfjehhkepox5hejbplu 26 14 , , , work_gb5rlsphfjehhkepox5hejbplu 26 15 spleen spleen NN work_gb5rlsphfjehhkepox5hejbplu 26 16 and and CC work_gb5rlsphfjehhkepox5hejbplu 26 17 brown brown JJ work_gb5rlsphfjehhkepox5hejbplu 26 18 adipose adipose NN work_gb5rlsphfjehhkepox5hejbplu 26 19 tis- tis- DT work_gb5rlsphfjehhkepox5hejbplu 26 20 sue sue NNP work_gb5rlsphfjehhkepox5hejbplu 26 21 were be VBD work_gb5rlsphfjehhkepox5hejbplu 26 22 patch patch NN work_gb5rlsphfjehhkepox5hejbplu 26 23 clamped clamp VBN work_gb5rlsphfjehhkepox5hejbplu 26 24 in in IN work_gb5rlsphfjehhkepox5hejbplu 26 25 the the DT work_gb5rlsphfjehhkepox5hejbplu 26 26 whole whole JJ work_gb5rlsphfjehhkepox5hejbplu 26 27 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 26 28 mitoplast mitoplast JJ work_gb5rlsphfjehhkepox5hejbplu 26 29 configuration configuration NN work_gb5rlsphfjehhkepox5hejbplu 26 30 . . . work_gb5rlsphfjehhkepox5hejbplu 27 1 Voltage voltage NN work_gb5rlsphfjehhkepox5hejbplu 27 2 step step NN work_gb5rlsphfjehhkepox5hejbplu 27 3 and and CC work_gb5rlsphfjehhkepox5hejbplu 27 4 ramp ramp NN work_gb5rlsphfjehhkepox5hejbplu 27 5 protocols protocol NNS work_gb5rlsphfjehhkepox5hejbplu 27 6 covering cover VBG work_gb5rlsphfjehhkepox5hejbplu 27 7 the the DT work_gb5rlsphfjehhkepox5hejbplu 27 8 whole whole JJ work_gb5rlsphfjehhkepox5hejbplu 27 9 range range NN work_gb5rlsphfjehhkepox5hejbplu 27 10 of of IN work_gb5rlsphfjehhkepox5hejbplu 27 11 physiological physiological JJ work_gb5rlsphfjehhkepox5hejbplu 27 12 potentials potential NNS work_gb5rlsphfjehhkepox5hejbplu 27 13 were be VBD work_gb5rlsphfjehhkepox5hejbplu 27 14 ap- ap- RB work_gb5rlsphfjehhkepox5hejbplu 27 15 plied ply VBN work_gb5rlsphfjehhkepox5hejbplu 27 16 to to TO work_gb5rlsphfjehhkepox5hejbplu 27 17 elicit elicit VB work_gb5rlsphfjehhkepox5hejbplu 27 18 the the DT work_gb5rlsphfjehhkepox5hejbplu 27 19 inwardly inwardly RB work_gb5rlsphfjehhkepox5hejbplu 27 20 rectifying rectify VBG work_gb5rlsphfjehhkepox5hejbplu 27 21 Ca2þcurrent ca2þcurrent NN work_gb5rlsphfjehhkepox5hejbplu 27 22 sensitive sensitive JJ work_gb5rlsphfjehhkepox5hejbplu 27 23 to to IN work_gb5rlsphfjehhkepox5hejbplu 27 24 RuR rur NN work_gb5rlsphfjehhkepox5hejbplu 27 25 known know VBN work_gb5rlsphfjehhkepox5hejbplu 27 26 as as IN work_gb5rlsphfjehhkepox5hejbplu 27 27 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 27 28 . . . work_gb5rlsphfjehhkepox5hejbplu 28 1 The the DT work_gb5rlsphfjehhkepox5hejbplu 28 2 distribution distribution NN work_gb5rlsphfjehhkepox5hejbplu 28 3 of of IN work_gb5rlsphfjehhkepox5hejbplu 28 4 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 28 5 current current JJ work_gb5rlsphfjehhkepox5hejbplu 28 6 densities density NNS work_gb5rlsphfjehhkepox5hejbplu 28 7 between between IN work_gb5rlsphfjehhkepox5hejbplu 28 8 tissues tissue NNS work_gb5rlsphfjehhkepox5hejbplu 28 9 was be VBD work_gb5rlsphfjehhkepox5hejbplu 28 10 as as IN work_gb5rlsphfjehhkepox5hejbplu 28 11 fol- fol- NN work_gb5rlsphfjehhkepox5hejbplu 28 12 lows low NNS work_gb5rlsphfjehhkepox5hejbplu 28 13 : : : work_gb5rlsphfjehhkepox5hejbplu 28 14 spleen spleen NNP work_gb5rlsphfjehhkepox5hejbplu 28 15 > > XX work_gb5rlsphfjehhkepox5hejbplu 28 16 brown brown NNP work_gb5rlsphfjehhkepox5hejbplu 28 17 adipose adipose NNP work_gb5rlsphfjehhkepox5hejbplu 28 18 tissue tissue NNP work_gb5rlsphfjehhkepox5hejbplu 28 19 z z NN work_gb5rlsphfjehhkepox5hejbplu 28 20 skeletal skeletal JJ work_gb5rlsphfjehhkepox5hejbplu 28 21 muscle muscle NN work_gb5rlsphfjehhkepox5hejbplu 28 22 > > XX work_gb5rlsphfjehhkepox5hejbplu 28 23 kidney kidney NNP work_gb5rlsphfjehhkepox5hejbplu 28 24 > > XX work_gb5rlsphfjehhkepox5hejbplu 28 25 liver liver NNP work_gb5rlsphfjehhkepox5hejbplu 28 26 > > XX work_gb5rlsphfjehhkepox5hejbplu 28 27 > > XX work_gb5rlsphfjehhkepox5hejbplu 28 28 heart heart NN work_gb5rlsphfjehhkepox5hejbplu 28 29 . . . work_gb5rlsphfjehhkepox5hejbplu 29 1 Interestingly interestingly RB work_gb5rlsphfjehhkepox5hejbplu 29 2 , , , work_gb5rlsphfjehhkepox5hejbplu 29 3 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 29 4 current current JJ work_gb5rlsphfjehhkepox5hejbplu 29 5 density density NN work_gb5rlsphfjehhkepox5hejbplu 29 6 in in IN work_gb5rlsphfjehhkepox5hejbplu 29 7 heart heart NN work_gb5rlsphfjehhkepox5hejbplu 29 8 was be VBD work_gb5rlsphfjehhkepox5hejbplu 29 9 about about RB work_gb5rlsphfjehhkepox5hejbplu 29 10 10 10 CD work_gb5rlsphfjehhkepox5hejbplu 29 11 times time NNS work_gb5rlsphfjehhkepox5hejbplu 29 12 smaller small JJR work_gb5rlsphfjehhkepox5hejbplu 29 13 than than IN work_gb5rlsphfjehhkepox5hejbplu 29 14 in in IN work_gb5rlsphfjehhkepox5hejbplu 29 15 skeletal skeletal JJ work_gb5rlsphfjehhkepox5hejbplu 29 16 muscle muscle NN work_gb5rlsphfjehhkepox5hejbplu 29 17 . . . work_gb5rlsphfjehhkepox5hejbplu 30 1 Our -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 30 2 results result NNS work_gb5rlsphfjehhkepox5hejbplu 30 3 support support VBP work_gb5rlsphfjehhkepox5hejbplu 30 4 the the DT work_gb5rlsphfjehhkepox5hejbplu 30 5 view view NN work_gb5rlsphfjehhkepox5hejbplu 30 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 30 7 a a DT work_gb5rlsphfjehhkepox5hejbplu 30 8 differential differential JJ work_gb5rlsphfjehhkepox5hejbplu 30 9 tissue tissue NN work_gb5rlsphfjehhkepox5hejbplu 30 10 activity activity NN work_gb5rlsphfjehhkepox5hejbplu 30 11 of of IN work_gb5rlsphfjehhkepox5hejbplu 30 12 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 30 13 , , , work_gb5rlsphfjehhkepox5hejbplu 30 14 which which WDT work_gb5rlsphfjehhkepox5hejbplu 30 15 can can MD work_gb5rlsphfjehhkepox5hejbplu 30 16 be be VB work_gb5rlsphfjehhkepox5hejbplu 30 17 explained explain VBN work_gb5rlsphfjehhkepox5hejbplu 30 18 by by IN work_gb5rlsphfjehhkepox5hejbplu 30 19 either either CC work_gb5rlsphfjehhkepox5hejbplu 30 20 a a DT work_gb5rlsphfjehhkepox5hejbplu 30 21 different different JJ work_gb5rlsphfjehhkepox5hejbplu 30 22 distribution distribution NN work_gb5rlsphfjehhkepox5hejbplu 30 23 of of IN work_gb5rlsphfjehhkepox5hejbplu 30 24 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 30 25 channel channel NN work_gb5rlsphfjehhkepox5hejbplu 30 26 and/or and/or CC work_gb5rlsphfjehhkepox5hejbplu 30 27 by by IN work_gb5rlsphfjehhkepox5hejbplu 30 28 a a DT work_gb5rlsphfjehhkepox5hejbplu 30 29 different different JJ work_gb5rlsphfjehhkepox5hejbplu 30 30 expression expression NN work_gb5rlsphfjehhkepox5hejbplu 30 31 of of IN work_gb5rlsphfjehhkepox5hejbplu 30 32 its -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 30 33 regulatory regulatory JJ work_gb5rlsphfjehhkepox5hejbplu 30 34 subunits subunit NNS work_gb5rlsphfjehhkepox5hejbplu 30 35 confer- confer- VBG work_gb5rlsphfjehhkepox5hejbplu 30 36 ing e VBG work_gb5rlsphfjehhkepox5hejbplu 30 37 various various JJ work_gb5rlsphfjehhkepox5hejbplu 30 38 modes mode NNS work_gb5rlsphfjehhkepox5hejbplu 30 39 of of IN work_gb5rlsphfjehhkepox5hejbplu 30 40 physiological physiological JJ work_gb5rlsphfjehhkepox5hejbplu 30 41 regulation regulation NN work_gb5rlsphfjehhkepox5hejbplu 30 42 . . . work_gb5rlsphfjehhkepox5hejbplu 31 1 Further further RB work_gb5rlsphfjehhkepox5hejbplu 31 2 on on RB work_gb5rlsphfjehhkepox5hejbplu 31 3 , , , work_gb5rlsphfjehhkepox5hejbplu 31 4 in in IN work_gb5rlsphfjehhkepox5hejbplu 31 5 order order NN work_gb5rlsphfjehhkepox5hejbplu 31 6 to to TO work_gb5rlsphfjehhkepox5hejbplu 31 7 investigate investigate VB work_gb5rlsphfjehhkepox5hejbplu 31 8 the the DT work_gb5rlsphfjehhkepox5hejbplu 31 9 putative putative JJ work_gb5rlsphfjehhkepox5hejbplu 31 10 direct direct JJ work_gb5rlsphfjehhkepox5hejbplu 31 11 contribution contribution NN work_gb5rlsphfjehhkepox5hejbplu 31 12 of of IN work_gb5rlsphfjehhkepox5hejbplu 31 13 Uncou- Uncou- NNP work_gb5rlsphfjehhkepox5hejbplu 31 14 pling ple VBG work_gb5rlsphfjehhkepox5hejbplu 31 15 Protein Protein NNP work_gb5rlsphfjehhkepox5hejbplu 31 16 Isoform Isoform NNP work_gb5rlsphfjehhkepox5hejbplu 31 17 2 2 CD work_gb5rlsphfjehhkepox5hejbplu 31 18 and and CC work_gb5rlsphfjehhkepox5hejbplu 31 19 3 3 CD work_gb5rlsphfjehhkepox5hejbplu 31 20 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 31 21 UCP2/3 UCP2/3 NNP work_gb5rlsphfjehhkepox5hejbplu 31 22 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 31 23 to to IN work_gb5rlsphfjehhkepox5hejbplu 31 24 the the DT work_gb5rlsphfjehhkepox5hejbplu 31 25 uniporter uniporter NN work_gb5rlsphfjehhkepox5hejbplu 31 26 , , , work_gb5rlsphfjehhkepox5hejbplu 31 27 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 31 28 investigated investigate VBD work_gb5rlsphfjehhkepox5hejbplu 31 29 MCU MCU NNP work_gb5rlsphfjehhkepox5hejbplu 31 30 properties property NNS work_gb5rlsphfjehhkepox5hejbplu 31 31 in in IN work_gb5rlsphfjehhkepox5hejbplu 31 32 wild wild JJ work_gb5rlsphfjehhkepox5hejbplu 31 33 type type NN work_gb5rlsphfjehhkepox5hejbplu 31 34 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 31 35 WT WT NNP work_gb5rlsphfjehhkepox5hejbplu 31 36 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 31 37 mouse mouse NN work_gb5rlsphfjehhkepox5hejbplu 31 38 tissues tissue NNS work_gb5rlsphfjehhkepox5hejbplu 31 39 where where WRB work_gb5rlsphfjehhkepox5hejbplu 31 40 these these DT work_gb5rlsphfjehhkepox5hejbplu 31 41 two two CD work_gb5rlsphfjehhkepox5hejbplu 31 42 proteins protein NNS work_gb5rlsphfjehhkepox5hejbplu 31 43 have have VBP work_gb5rlsphfjehhkepox5hejbplu 31 44 been be VBN work_gb5rlsphfjehhkepox5hejbplu 31 45 found find VBN work_gb5rlsphfjehhkepox5hejbplu 31 46 to to TO work_gb5rlsphfjehhkepox5hejbplu 31 47 have have VB work_gb5rlsphfjehhkepox5hejbplu 31 48 a a DT work_gb5rlsphfjehhkepox5hejbplu 31 49 major major JJ work_gb5rlsphfjehhkepox5hejbplu 31 50 role role NN work_gb5rlsphfjehhkepox5hejbplu 31 51 and and CC work_gb5rlsphfjehhkepox5hejbplu 31 52 compared compare VBD work_gb5rlsphfjehhkepox5hejbplu 31 53 its -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 31 54 properties property NNS work_gb5rlsphfjehhkepox5hejbplu 31 55 in in IN work_gb5rlsphfjehhkepox5hejbplu 31 56 the the DT work_gb5rlsphfjehhkepox5hejbplu 31 57 corre- corre- JJ work_gb5rlsphfjehhkepox5hejbplu 31 58 spondent spondent JJ work_gb5rlsphfjehhkepox5hejbplu 31 59 tissues tissue NNS work_gb5rlsphfjehhkepox5hejbplu 31 60 of of IN work_gb5rlsphfjehhkepox5hejbplu 31 61 UCP2 UCP2 NNP work_gb5rlsphfjehhkepox5hejbplu 31 62 and and CC work_gb5rlsphfjehhkepox5hejbplu 31 63 UCP3 UCP3 NNP work_gb5rlsphfjehhkepox5hejbplu 31 64 KO KO NNP work_gb5rlsphfjehhkepox5hejbplu 31 65 mice mouse NNS work_gb5rlsphfjehhkepox5hejbplu 31 66 . . . work_gb5rlsphfjehhkepox5hejbplu 32 1 We -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 32 2 found find VBD work_gb5rlsphfjehhkepox5hejbplu 32 3 no no DT work_gb5rlsphfjehhkepox5hejbplu 32 4 significant significant JJ work_gb5rlsphfjehhkepox5hejbplu 32 5 differ- differ- JJ work_gb5rlsphfjehhkepox5hejbplu 32 6 ences ence NNS work_gb5rlsphfjehhkepox5hejbplu 32 7 in in IN work_gb5rlsphfjehhkepox5hejbplu 32 8 calcium calcium NN work_gb5rlsphfjehhkepox5hejbplu 32 9 currents current NNS work_gb5rlsphfjehhkepox5hejbplu 32 10 of of IN work_gb5rlsphfjehhkepox5hejbplu 32 11 any any DT work_gb5rlsphfjehhkepox5hejbplu 32 12 of of IN work_gb5rlsphfjehhkepox5hejbplu 32 13 the the DT work_gb5rlsphfjehhkepox5hejbplu 32 14 WT WT NNP work_gb5rlsphfjehhkepox5hejbplu 32 15 tissues tissue NNS work_gb5rlsphfjehhkepox5hejbplu 32 16 studied study VBD work_gb5rlsphfjehhkepox5hejbplu 32 17 compared compare VBN work_gb5rlsphfjehhkepox5hejbplu 32 18 to to IN work_gb5rlsphfjehhkepox5hejbplu 32 19 their -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 32 20 UCP2/3 UCP2/3 NNP work_gb5rlsphfjehhkepox5hejbplu 32 21 KO KO NNP work_gb5rlsphfjehhkepox5hejbplu 32 22 counterparts counterpart NNS work_gb5rlsphfjehhkepox5hejbplu 32 23 . . . work_gb5rlsphfjehhkepox5hejbplu 33 1 2218-Plat 2218-plat CD work_gb5rlsphfjehhkepox5hejbplu 33 2 SR SR NNP work_gb5rlsphfjehhkepox5hejbplu 33 3 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 33 4 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 33 5 Ultrastructure Ultrastructure NNP work_gb5rlsphfjehhkepox5hejbplu 33 6 in in IN work_gb5rlsphfjehhkepox5hejbplu 33 7 the the DT work_gb5rlsphfjehhkepox5hejbplu 33 8 Heart heart NN work_gb5rlsphfjehhkepox5hejbplu 33 9 of of IN work_gb5rlsphfjehhkepox5hejbplu 33 10 Normal Normal NNP work_gb5rlsphfjehhkepox5hejbplu 33 11 and and CC work_gb5rlsphfjehhkepox5hejbplu 33 12 Ethanol Ethanol NNP work_gb5rlsphfjehhkepox5hejbplu 33 13 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 33 14 Fed Fed NNP work_gb5rlsphfjehhkepox5hejbplu 33 15 Rats Rats NNP work_gb5rlsphfjehhkepox5hejbplu 33 16 Gyorgy Gyorgy NNP work_gb5rlsphfjehhkepox5hejbplu 33 17 Csordas1 Csordas1 NNP work_gb5rlsphfjehhkepox5hejbplu 33 18 , , , work_gb5rlsphfjehhkepox5hejbplu 33 19 David David NNP work_gb5rlsphfjehhkepox5hejbplu 33 20 Mankus2 Mankus2 NNP work_gb5rlsphfjehhkepox5hejbplu 33 21 , , , work_gb5rlsphfjehhkepox5hejbplu 33 22 Tanvir Tanvir NNP work_gb5rlsphfjehhkepox5hejbplu 33 23 Shaikh2 Shaikh2 NNP work_gb5rlsphfjehhkepox5hejbplu 33 24 , , , work_gb5rlsphfjehhkepox5hejbplu 33 25 Xing Xing NNP work_gb5rlsphfjehhkepox5hejbplu 33 26 Meng2 meng2 NN work_gb5rlsphfjehhkepox5hejbplu 33 27 , , , work_gb5rlsphfjehhkepox5hejbplu 33 28 Jan Jan NNP work_gb5rlsphfjehhkepox5hejbplu 33 29 Hoek1 hoek1 NN work_gb5rlsphfjehhkepox5hejbplu 33 30 , , , work_gb5rlsphfjehhkepox5hejbplu 33 31 Carmen Carmen NNP work_gb5rlsphfjehhkepox5hejbplu 33 32 Mannella2 Mannella2 NNP work_gb5rlsphfjehhkepox5hejbplu 33 33 , , , work_gb5rlsphfjehhkepox5hejbplu 33 34 Gyorgy Gyorgy NNP work_gb5rlsphfjehhkepox5hejbplu 33 35 Hajnoczky1 Hajnoczky1 NNP work_gb5rlsphfjehhkepox5hejbplu 33 36 . . . work_gb5rlsphfjehhkepox5hejbplu 34 1 1 1 CD work_gb5rlsphfjehhkepox5hejbplu 34 2 Thomas Thomas NNP work_gb5rlsphfjehhkepox5hejbplu 34 3 Jefferson Jefferson NNP work_gb5rlsphfjehhkepox5hejbplu 34 4 University University NNP work_gb5rlsphfjehhkepox5hejbplu 34 5 , , , work_gb5rlsphfjehhkepox5hejbplu 34 6 Philadelphia Philadelphia NNP work_gb5rlsphfjehhkepox5hejbplu 34 7 , , , work_gb5rlsphfjehhkepox5hejbplu 34 8 PA PA NNP work_gb5rlsphfjehhkepox5hejbplu 34 9 , , , work_gb5rlsphfjehhkepox5hejbplu 34 10 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 34 11 , , , work_gb5rlsphfjehhkepox5hejbplu 34 12 2 2 CD work_gb5rlsphfjehhkepox5hejbplu 34 13 Wadsworth Wadsworth NNP work_gb5rlsphfjehhkepox5hejbplu 34 14 Center Center NNP work_gb5rlsphfjehhkepox5hejbplu 34 15 , , , work_gb5rlsphfjehhkepox5hejbplu 34 16 Albany Albany NNP work_gb5rlsphfjehhkepox5hejbplu 34 17 , , , work_gb5rlsphfjehhkepox5hejbplu 34 18 NY NY NNP work_gb5rlsphfjehhkepox5hejbplu 34 19 , , , work_gb5rlsphfjehhkepox5hejbplu 34 20 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 34 21 . . . work_gb5rlsphfjehhkepox5hejbplu 35 1 Chronic chronic JJ work_gb5rlsphfjehhkepox5hejbplu 35 2 alcoholism alcoholism NN work_gb5rlsphfjehhkepox5hejbplu 35 3 causes cause VBZ work_gb5rlsphfjehhkepox5hejbplu 35 4 various various JJ work_gb5rlsphfjehhkepox5hejbplu 35 5 forms form NNS work_gb5rlsphfjehhkepox5hejbplu 35 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 35 7 stress stress NN work_gb5rlsphfjehhkepox5hejbplu 35 8 in in IN work_gb5rlsphfjehhkepox5hejbplu 35 9 the the DT work_gb5rlsphfjehhkepox5hejbplu 35 10 heart heart NN work_gb5rlsphfjehhkepox5hejbplu 35 11 , , , work_gb5rlsphfjehhkepox5hejbplu 35 12 and and CC work_gb5rlsphfjehhkepox5hejbplu 35 13 this this DT work_gb5rlsphfjehhkepox5hejbplu 35 14 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 35 15 often often RB work_gb5rlsphfjehhkepox5hejbplu 35 16 accompanied accompany VBN work_gb5rlsphfjehhkepox5hejbplu 35 17 by by IN work_gb5rlsphfjehhkepox5hejbplu 35 18 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 35 19 dysfunction dysfunction NN work_gb5rlsphfjehhkepox5hejbplu 35 20 . . . work_gb5rlsphfjehhkepox5hejbplu 36 1 A a DT work_gb5rlsphfjehhkepox5hejbplu 36 2 putative putative JJ work_gb5rlsphfjehhkepox5hejbplu 36 3 source source NN work_gb5rlsphfjehhkepox5hejbplu 36 4 of of IN work_gb5rlsphfjehhkepox5hejbplu 36 5 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 36 6 dysfunction dysfunction NN work_gb5rlsphfjehhkepox5hejbplu 36 7 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 36 8 SR sr JJ work_gb5rlsphfjehhkepox5hejbplu 36 9 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 36 10 mitochondrial mitochondrial JJ work_gb5rlsphfjehhkepox5hejbplu 36 11 stress stress NN work_gb5rlsphfjehhkepox5hejbplu 36 12 and and CC work_gb5rlsphfjehhkepox5hejbplu 36 13 the the DT work_gb5rlsphfjehhkepox5hejbplu 36 14 ensuing ensue VBG work_gb5rlsphfjehhkepox5hejbplu 36 15 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 36 16 Ca2þ ca2þ NN work_gb5rlsphfjehhkepox5hejbplu 36 17 overload overload NN work_gb5rlsphfjehhkepox5hejbplu 36 18 . . . work_gb5rlsphfjehhkepox5hejbplu 37 1 To to TO work_gb5rlsphfjehhkepox5hejbplu 37 2 test test VB work_gb5rlsphfjehhkepox5hejbplu 37 3 this this DT work_gb5rlsphfjehhkepox5hejbplu 37 4 possibility possibility NN work_gb5rlsphfjehhkepox5hejbplu 37 5 , , , work_gb5rlsphfjehhkepox5hejbplu 37 6 first first RB work_gb5rlsphfjehhkepox5hejbplu 37 7 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 37 8 isolated isolate VBD work_gb5rlsphfjehhkepox5hejbplu 37 9 mitochondria mitochondrion NNS work_gb5rlsphfjehhkepox5hejbplu 37 10 from from IN work_gb5rlsphfjehhkepox5hejbplu 37 11 chronic chronic JJ work_gb5rlsphfjehhkepox5hejbplu 37 12 ethanol ethanol NN work_gb5rlsphfjehhkepox5hejbplu 37 13 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 37 14 fed fed NNP work_gb5rlsphfjehhkepox5hejbplu 37 15 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 37 16 6 6 CD work_gb5rlsphfjehhkepox5hejbplu 37 17 months month NNS work_gb5rlsphfjehhkepox5hejbplu 37 18 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 37 19 and and CC work_gb5rlsphfjehhkepox5hejbplu 37 20 paired pair VBD work_gb5rlsphfjehhkepox5hejbplu 37 21 control control NN work_gb5rlsphfjehhkepox5hejbplu 37 22 rats rat NNS work_gb5rlsphfjehhkepox5hejbplu 37 23 , , , work_gb5rlsphfjehhkepox5hejbplu 37 24 and and CC work_gb5rlsphfjehhkepox5hejbplu 37 25 documented document VBN work_gb5rlsphfjehhkepox5hejbplu 37 26 ethanol- ethanol- JJ work_gb5rlsphfjehhkepox5hejbplu 37 27 dependent dependent JJ work_gb5rlsphfjehhkepox5hejbplu 37 28 sensitization sensitization NN work_gb5rlsphfjehhkepox5hejbplu 37 29 to to IN work_gb5rlsphfjehhkepox5hejbplu 37 30 Ca Ca NNP work_gb5rlsphfjehhkepox5hejbplu 37 31 2þ 2þ CD work_gb5rlsphfjehhkepox5hejbplu 37 32 and and CC work_gb5rlsphfjehhkepox5hejbplu 37 33 ROS ROS NNP work_gb5rlsphfjehhkepox5hejbplu 37 34 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 37 35 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 37 36 permeabilization permeabilization NN work_gb5rlsphfjehhkepox5hejbplu 37 37 . . . work_gb5rlsphfjehhkepox5hejbplu 38 1 To to IN work_gb5rlsphfjehhkepox5hejbplu 38 2 evalu- evalu- NNS work_gb5rlsphfjehhkepox5hejbplu 38 3 ate eat VBD work_gb5rlsphfjehhkepox5hejbplu 38 4 the the DT work_gb5rlsphfjehhkepox5hejbplu 38 5 ultrastructural ultrastructural JJ work_gb5rlsphfjehhkepox5hejbplu 38 6 basis basis NN work_gb5rlsphfjehhkepox5hejbplu 38 7 of of IN work_gb5rlsphfjehhkepox5hejbplu 38 8 the the DT work_gb5rlsphfjehhkepox5hejbplu 38 9 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 38 10 impairments impairment NNS work_gb5rlsphfjehhkepox5hejbplu 38 11 , , , work_gb5rlsphfjehhkepox5hejbplu 38 12 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 38 13 performed perform VBD work_gb5rlsphfjehhkepox5hejbplu 38 14 transmission transmission NN work_gb5rlsphfjehhkepox5hejbplu 38 15 electron electron NNP work_gb5rlsphfjehhkepox5hejbplu 38 16 microscopy microscopy JJ work_gb5rlsphfjehhkepox5hejbplu 38 17 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 38 18 TEM TEM NNP work_gb5rlsphfjehhkepox5hejbplu 38 19 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 38 20 and and CC work_gb5rlsphfjehhkepox5hejbplu 38 21 electron electron NNP work_gb5rlsphfjehhkepox5hejbplu 38 22 tomography tomography NN work_gb5rlsphfjehhkepox5hejbplu 38 23 studies study NNS work_gb5rlsphfjehhkepox5hejbplu 38 24 of of IN work_gb5rlsphfjehhkepox5hejbplu 38 25 left left JJ work_gb5rlsphfjehhkepox5hejbplu 38 26 ventricular ventricular JJ work_gb5rlsphfjehhkepox5hejbplu 38 27 muscle muscle NN work_gb5rlsphfjehhkepox5hejbplu 38 28 . . . work_gb5rlsphfjehhkepox5hejbplu 39 1 The the DT work_gb5rlsphfjehhkepox5hejbplu 39 2 overall overall JJ work_gb5rlsphfjehhkepox5hejbplu 39 3 ultrastructure ultrastructure NN work_gb5rlsphfjehhkepox5hejbplu 39 4 of of IN work_gb5rlsphfjehhkepox5hejbplu 39 5 the the DT work_gb5rlsphfjehhkepox5hejbplu 39 6 myocytes myocytes NNPS work_gb5rlsphfjehhkepox5hejbplu 39 7 became become VBD work_gb5rlsphfjehhkepox5hejbplu 39 8 less less RBR work_gb5rlsphfjehhkepox5hejbplu 39 9 organized organized JJ work_gb5rlsphfjehhkepox5hejbplu 39 10 in in IN work_gb5rlsphfjehhkepox5hejbplu 39 11 the the DT work_gb5rlsphfjehhkepox5hejbplu 39 12 ethanol ethanol NN work_gb5rlsphfjehhkepox5hejbplu 39 13 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 39 14 fed feed VBN work_gb5rlsphfjehhkepox5hejbplu 39 15 condition condition NN work_gb5rlsphfjehhkepox5hejbplu 39 16 . . . work_gb5rlsphfjehhkepox5hejbplu 40 1 Also also RB work_gb5rlsphfjehhkepox5hejbplu 40 2 , , , work_gb5rlsphfjehhkepox5hejbplu 40 3 a a DT work_gb5rlsphfjehhkepox5hejbplu 40 4 considerable considerable JJ work_gb5rlsphfjehhkepox5hejbplu 40 5 fraction fraction NN work_gb5rlsphfjehhkepox5hejbplu 40 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 40 7 the the DT work_gb5rlsphfjehhkepox5hejbplu 40 8 mitochondria mitochondria NN work_gb5rlsphfjehhkepox5hejbplu 40 9 lost lose VBD work_gb5rlsphfjehhkepox5hejbplu 40 10 the the DT work_gb5rlsphfjehhkepox5hejbplu 40 11 highly highly RB work_gb5rlsphfjehhkepox5hejbplu 40 12 ordered order VBN work_gb5rlsphfjehhkepox5hejbplu 40 13 structure structure NN work_gb5rlsphfjehhkepox5hejbplu 40 14 of of IN work_gb5rlsphfjehhkepox5hejbplu 40 15 the the DT work_gb5rlsphfjehhkepox5hejbplu 40 16 cristae cristae NN work_gb5rlsphfjehhkepox5hejbplu 40 17 and and CC work_gb5rlsphfjehhkepox5hejbplu 40 18 showed show VBD work_gb5rlsphfjehhkepox5hejbplu 40 19 an an DT work_gb5rlsphfjehhkepox5hejbplu 40 20 increase increase NN work_gb5rlsphfjehhkepox5hejbplu 40 21 in in IN work_gb5rlsphfjehhkepox5hejbplu 40 22 the the DT work_gb5rlsphfjehhkepox5hejbplu 40 23 cross cross JJ work_gb5rlsphfjehhkepox5hejbplu 40 24 - - JJ work_gb5rlsphfjehhkepox5hejbplu 40 25 sectional sectional JJ work_gb5rlsphfjehhkepox5hejbplu 40 26 area area NN work_gb5rlsphfjehhkepox5hejbplu 40 27 . . . work_gb5rlsphfjehhkepox5hejbplu 41 1 However however RB work_gb5rlsphfjehhkepox5hejbplu 41 2 , , , work_gb5rlsphfjehhkepox5hejbplu 41 3 the the DT work_gb5rlsphfjehhkepox5hejbplu 41 4 size size NN work_gb5rlsphfjehhkepox5hejbplu 41 5 of of IN work_gb5rlsphfjehhkepox5hejbplu 41 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 41 7 SR- SR- NNP work_gb5rlsphfjehhkepox5hejbplu 41 8 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 41 9 associations association NNS work_gb5rlsphfjehhkepox5hejbplu 41 10 and and CC work_gb5rlsphfjehhkepox5hejbplu 41 11 the the DT work_gb5rlsphfjehhkepox5hejbplu 41 12 gap gap NN work_gb5rlsphfjehhkepox5hejbplu 41 13 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 41 14 width width NN work_gb5rlsphfjehhkepox5hejbplu 41 15 at at IN work_gb5rlsphfjehhkepox5hejbplu 41 16 the the DT work_gb5rlsphfjehhkepox5hejbplu 41 17 interface interface NN work_gb5rlsphfjehhkepox5hejbplu 41 18 was be VBD work_gb5rlsphfjehhkepox5hejbplu 41 19 unchanged unchanged JJ work_gb5rlsphfjehhkepox5hejbplu 41 20 . . . work_gb5rlsphfjehhkepox5hejbplu 42 1 Evaluation evaluation NN work_gb5rlsphfjehhkepox5hejbplu 42 2 of of IN work_gb5rlsphfjehhkepox5hejbplu 42 3 the the DT work_gb5rlsphfjehhkepox5hejbplu 42 4 SR sr JJ work_gb5rlsphfjehhkepox5hejbplu 42 5 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 42 6 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 42 7 tethers tether NNS work_gb5rlsphfjehhkepox5hejbplu 42 8 by by IN work_gb5rlsphfjehhkepox5hejbplu 42 9 electron electron NNP work_gb5rlsphfjehhkepox5hejbplu 42 10 tomography tomography NNP work_gb5rlsphfjehhkepox5hejbplu 42 11 indicates indicate VBZ work_gb5rlsphfjehhkepox5hejbplu 42 12 that that IN work_gb5rlsphfjehhkepox5hejbplu 42 13 they -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 42 14 occur occur VBP work_gb5rlsphfjehhkepox5hejbplu 42 15 in in IN work_gb5rlsphfjehhkepox5hejbplu 42 16 clusters cluster NNS work_gb5rlsphfjehhkepox5hejbplu 42 17 and and CC work_gb5rlsphfjehhkepox5hejbplu 42 18 display display VB work_gb5rlsphfjehhkepox5hejbplu 42 19 heterogeneity heterogeneity NN work_gb5rlsphfjehhkepox5hejbplu 42 20 in in IN work_gb5rlsphfjehhkepox5hejbplu 42 21 length length NN work_gb5rlsphfjehhkepox5hejbplu 42 22 , , , work_gb5rlsphfjehhkepox5hejbplu 42 23 as as RB work_gb5rlsphfjehhkepox5hejbplu 42 24 previously previously RB work_gb5rlsphfjehhkepox5hejbplu 42 25 re- re- RB work_gb5rlsphfjehhkepox5hejbplu 42 26 ported port VBN work_gb5rlsphfjehhkepox5hejbplu 42 27 for for IN work_gb5rlsphfjehhkepox5hejbplu 42 28 ER ER NNP work_gb5rlsphfjehhkepox5hejbplu 42 29 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 42 30 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 42 31 tethers tether NNS work_gb5rlsphfjehhkepox5hejbplu 42 32 in in IN work_gb5rlsphfjehhkepox5hejbplu 42 33 normal normal JJ work_gb5rlsphfjehhkepox5hejbplu 42 34 rat rat NN work_gb5rlsphfjehhkepox5hejbplu 42 35 liver liver NN work_gb5rlsphfjehhkepox5hejbplu 42 36 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 42 37 Csordas Csordas NNP work_gb5rlsphfjehhkepox5hejbplu 42 38 et et NNP work_gb5rlsphfjehhkepox5hejbplu 42 39 al al NNP work_gb5rlsphfjehhkepox5hejbplu 42 40 , , , work_gb5rlsphfjehhkepox5hejbplu 42 41 2006 2006 CD work_gb5rlsphfjehhkepox5hejbplu 42 42 , , , work_gb5rlsphfjehhkepox5hejbplu 42 43 J J NNP work_gb5rlsphfjehhkepox5hejbplu 42 44 Cell Cell NNP work_gb5rlsphfjehhkepox5hejbplu 42 45 Biol Biol NNP work_gb5rlsphfjehhkepox5hejbplu 42 46 , , , work_gb5rlsphfjehhkepox5hejbplu 42 47 174:915 174:915 CD work_gb5rlsphfjehhkepox5hejbplu 42 48 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 42 49 . . . work_gb5rlsphfjehhkepox5hejbplu 43 1 Overall overall JJ work_gb5rlsphfjehhkepox5hejbplu 43 2 tether tether NN work_gb5rlsphfjehhkepox5hejbplu 43 3 length length NN work_gb5rlsphfjehhkepox5hejbplu 43 4 distribution distribution NN work_gb5rlsphfjehhkepox5hejbplu 43 5 appears appear VBZ work_gb5rlsphfjehhkepox5hejbplu 43 6 to to TO work_gb5rlsphfjehhkepox5hejbplu 43 7 be be VB work_gb5rlsphfjehhkepox5hejbplu 43 8 unaltered unaltere VBN work_gb5rlsphfjehhkepox5hejbplu 43 9 by by IN work_gb5rlsphfjehhkepox5hejbplu 43 10 alcohol alcohol NN work_gb5rlsphfjehhkepox5hejbplu 43 11 ingestion ingestion NN work_gb5rlsphfjehhkepox5hejbplu 43 12 . . . work_gb5rlsphfjehhkepox5hejbplu 44 1 Analyses analysis NNS work_gb5rlsphfjehhkepox5hejbplu 44 2 of of IN work_gb5rlsphfjehhkepox5hejbplu 44 3 effects effect NNS work_gb5rlsphfjehhkepox5hejbplu 44 4 of of IN work_gb5rlsphfjehhkepox5hejbplu 44 5 alcohol alcohol NN work_gb5rlsphfjehhkepox5hejbplu 44 6 ingestion ingestion NN work_gb5rlsphfjehhkepox5hejbplu 44 7 on on IN work_gb5rlsphfjehhkepox5hejbplu 44 8 tether tether NN work_gb5rlsphfjehhkepox5hejbplu 44 9 membrane membrane NN work_gb5rlsphfjehhkepox5hejbplu 44 10 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 44 11 surface surface NN work_gb5rlsphfjehhkepox5hejbplu 44 12 density density NN work_gb5rlsphfjehhkepox5hejbplu 44 13 and and CC work_gb5rlsphfjehhkepox5hejbplu 44 14 structural structural JJ work_gb5rlsphfjehhkepox5hejbplu 44 15 classes class NNS work_gb5rlsphfjehhkepox5hejbplu 44 16 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 44 17 linear linear JJ work_gb5rlsphfjehhkepox5hejbplu 44 18 , , , work_gb5rlsphfjehhkepox5hejbplu 44 19 V v NN work_gb5rlsphfjehhkepox5hejbplu 44 20 , , , work_gb5rlsphfjehhkepox5hejbplu 44 21 Y Y NNP work_gb5rlsphfjehhkepox5hejbplu 44 22 and and CC work_gb5rlsphfjehhkepox5hejbplu 44 23 more more JJR work_gb5rlsphfjehhkepox5hejbplu 44 24 com- com- NN work_gb5rlsphfjehhkepox5hejbplu 44 25 plex plex NN work_gb5rlsphfjehhkepox5hejbplu 44 26 shapes shape NNS work_gb5rlsphfjehhkepox5hejbplu 44 27 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 44 28 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 44 29 in in IN work_gb5rlsphfjehhkepox5hejbplu 44 30 progress progress NN work_gb5rlsphfjehhkepox5hejbplu 44 31 , , , work_gb5rlsphfjehhkepox5hejbplu 44 32 as as IN work_gb5rlsphfjehhkepox5hejbplu 44 33 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 44 34 3D 3d JJ work_gb5rlsphfjehhkepox5hejbplu 44 35 analysis analysis NN work_gb5rlsphfjehhkepox5hejbplu 44 36 of of IN work_gb5rlsphfjehhkepox5hejbplu 44 37 SER SER NNP work_gb5rlsphfjehhkepox5hejbplu 44 38 and and CC work_gb5rlsphfjehhkepox5hejbplu 44 39 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 44 40 inner- inner- NN work_gb5rlsphfjehhkepox5hejbplu 44 41 and and CC work_gb5rlsphfjehhkepox5hejbplu 44 42 outer outer JJ work_gb5rlsphfjehhkepox5hejbplu 44 43 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 44 44 membrane membrane NN work_gb5rlsphfjehhkepox5hejbplu 44 45 topologies topology NNS work_gb5rlsphfjehhkepox5hejbplu 44 46 . . . work_gb5rlsphfjehhkepox5hejbplu 45 1 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 45 2 Supported support VBN work_gb5rlsphfjehhkepox5hejbplu 45 3 by by IN work_gb5rlsphfjehhkepox5hejbplu 45 4 NIH NIH NNP work_gb5rlsphfjehhkepox5hejbplu 45 5 grant grant NN work_gb5rlsphfjehhkepox5hejbplu 45 6 1RC2AA019416 1rc2aa019416 CD work_gb5rlsphfjehhkepox5hejbplu 45 7 . . . work_gb5rlsphfjehhkepox5hejbplu 45 8 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 46 1 2219-Plat 2219-plat CD work_gb5rlsphfjehhkepox5hejbplu 46 2 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 46 3 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 46 4 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 46 5 Increases Increases NNPS work_gb5rlsphfjehhkepox5hejbplu 46 6 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 46 7 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 46 8 Localization Localization NNP work_gb5rlsphfjehhkepox5hejbplu 46 9 and and CC work_gb5rlsphfjehhkepox5hejbplu 46 10 Activation Activation NNP work_gb5rlsphfjehhkepox5hejbplu 46 11 in in IN work_gb5rlsphfjehhkepox5hejbplu 46 12 Non- Non- NNP work_gb5rlsphfjehhkepox5hejbplu 46 13 Apoptotic Apoptotic NNP work_gb5rlsphfjehhkepox5hejbplu 46 14 Cells Cells NNPS work_gb5rlsphfjehhkepox5hejbplu 46 15 Laurent Laurent NNP work_gb5rlsphfjehhkepox5hejbplu 46 16 M. M. NNP work_gb5rlsphfjehhkepox5hejbplu 46 17 Dejean1 Dejean1 NNP work_gb5rlsphfjehhkepox5hejbplu 46 18 , , , work_gb5rlsphfjehhkepox5hejbplu 46 19 Thibaud Thibaud NNP work_gb5rlsphfjehhkepox5hejbplu 46 20 T. T. NNP work_gb5rlsphfjehhkepox5hejbplu 46 21 Renault2 Renault2 NNP work_gb5rlsphfjehhkepox5hejbplu 46 22 , , , work_gb5rlsphfjehhkepox5hejbplu 46 23 Oscar Oscar NNP work_gb5rlsphfjehhkepox5hejbplu 46 24 Teijido3 Teijido3 NNP work_gb5rlsphfjehhkepox5hejbplu 46 25 , , , work_gb5rlsphfjehhkepox5hejbplu 46 26 Gisele Gisele NNP work_gb5rlsphfjehhkepox5hejbplu 46 27 Velours2 Velours2 NNP work_gb5rlsphfjehhkepox5hejbplu 46 28 , , , work_gb5rlsphfjehhkepox5hejbplu 46 29 Yogesh Yogesh NNP work_gb5rlsphfjehhkepox5hejbplu 46 30 Tengarai Tengarai NNP work_gb5rlsphfjehhkepox5hejbplu 46 31 Ganesan4 Ganesan4 NNP work_gb5rlsphfjehhkepox5hejbplu 46 32 , , , work_gb5rlsphfjehhkepox5hejbplu 46 33 Nadine Nadine NNP work_gb5rlsphfjehhkepox5hejbplu 46 34 Camougrand2 Camougrand2 NNP work_gb5rlsphfjehhkepox5hejbplu 46 35 , , , work_gb5rlsphfjehhkepox5hejbplu 46 36 Bruno Bruno NNP work_gb5rlsphfjehhkepox5hejbplu 46 37 Antonsson5 Antonsson5 NNP work_gb5rlsphfjehhkepox5hejbplu 46 38 , , , work_gb5rlsphfjehhkepox5hejbplu 46 39 Stephen Stephen NNP work_gb5rlsphfjehhkepox5hejbplu 46 40 Manon2 Manon2 NNP work_gb5rlsphfjehhkepox5hejbplu 46 41 . . . work_gb5rlsphfjehhkepox5hejbplu 47 1 1California 1California NNP work_gb5rlsphfjehhkepox5hejbplu 47 2 State State NNP work_gb5rlsphfjehhkepox5hejbplu 47 3 University University NNP work_gb5rlsphfjehhkepox5hejbplu 47 4 of of IN work_gb5rlsphfjehhkepox5hejbplu 47 5 Fresno Fresno NNP work_gb5rlsphfjehhkepox5hejbplu 47 6 , , , work_gb5rlsphfjehhkepox5hejbplu 47 7 Fresno Fresno NNP work_gb5rlsphfjehhkepox5hejbplu 47 8 , , , work_gb5rlsphfjehhkepox5hejbplu 47 9 CA CA NNP work_gb5rlsphfjehhkepox5hejbplu 47 10 , , , work_gb5rlsphfjehhkepox5hejbplu 47 11 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 47 12 , , , work_gb5rlsphfjehhkepox5hejbplu 47 13 2CNRS 2CNRS NNP work_gb5rlsphfjehhkepox5hejbplu 47 14 , , , work_gb5rlsphfjehhkepox5hejbplu 47 15 Institut Institut NNP work_gb5rlsphfjehhkepox5hejbplu 47 16 de de IN work_gb5rlsphfjehhkepox5hejbplu 47 17 Biochimie Biochimie NNP work_gb5rlsphfjehhkepox5hejbplu 47 18 et et NNP work_gb5rlsphfjehhkepox5hejbplu 47 19 de de NN work_gb5rlsphfjehhkepox5hejbplu 47 20 Génétique Génétique NNP work_gb5rlsphfjehhkepox5hejbplu 47 21 Cellulaires Cellulaires NNP work_gb5rlsphfjehhkepox5hejbplu 47 22 , , , work_gb5rlsphfjehhkepox5hejbplu 47 23 Bordeaux Bordeaux NNP work_gb5rlsphfjehhkepox5hejbplu 47 24 , , , work_gb5rlsphfjehhkepox5hejbplu 47 25 France France NNP work_gb5rlsphfjehhkepox5hejbplu 47 26 , , , work_gb5rlsphfjehhkepox5hejbplu 47 27 3NIH 3NIH NNP work_gb5rlsphfjehhkepox5hejbplu 47 28 , , , work_gb5rlsphfjehhkepox5hejbplu 47 29 NICHD NICHD NNP work_gb5rlsphfjehhkepox5hejbplu 47 30 , , , work_gb5rlsphfjehhkepox5hejbplu 47 31 Bethesda Bethesda NNP work_gb5rlsphfjehhkepox5hejbplu 47 32 , , , work_gb5rlsphfjehhkepox5hejbplu 47 33 MD MD NNP work_gb5rlsphfjehhkepox5hejbplu 47 34 , , , work_gb5rlsphfjehhkepox5hejbplu 47 35 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 47 36 , , , work_gb5rlsphfjehhkepox5hejbplu 47 37 4 4 CD work_gb5rlsphfjehhkepox5hejbplu 47 38 Memorial Memorial NNP work_gb5rlsphfjehhkepox5hejbplu 47 39 Sloan Sloan NNP work_gb5rlsphfjehhkepox5hejbplu 47 40 Kettering Kettering NNP work_gb5rlsphfjehhkepox5hejbplu 47 41 Cancer Cancer NNP work_gb5rlsphfjehhkepox5hejbplu 47 42 Center Center NNP work_gb5rlsphfjehhkepox5hejbplu 47 43 , , , work_gb5rlsphfjehhkepox5hejbplu 47 44 New New NNP work_gb5rlsphfjehhkepox5hejbplu 47 45 York York NNP work_gb5rlsphfjehhkepox5hejbplu 47 46 , , , work_gb5rlsphfjehhkepox5hejbplu 47 47 NY NY NNP work_gb5rlsphfjehhkepox5hejbplu 47 48 , , , work_gb5rlsphfjehhkepox5hejbplu 47 49 USA USA NNP work_gb5rlsphfjehhkepox5hejbplu 47 50 , , , work_gb5rlsphfjehhkepox5hejbplu 47 51 5 5 CD work_gb5rlsphfjehhkepox5hejbplu 47 52 Merck Merck NNP work_gb5rlsphfjehhkepox5hejbplu 47 53 Serrono Serrono NNP work_gb5rlsphfjehhkepox5hejbplu 47 54 S.A. S.A. NNP work_gb5rlsphfjehhkepox5hejbplu 47 55 , , , work_gb5rlsphfjehhkepox5hejbplu 47 56 Geneva Geneva NNP work_gb5rlsphfjehhkepox5hejbplu 47 57 Research Research NNP work_gb5rlsphfjehhkepox5hejbplu 47 58 Center Center NNP work_gb5rlsphfjehhkepox5hejbplu 47 59 , , , work_gb5rlsphfjehhkepox5hejbplu 47 60 Geneva Geneva NNP work_gb5rlsphfjehhkepox5hejbplu 47 61 , , , work_gb5rlsphfjehhkepox5hejbplu 47 62 Switzerland Switzerland NNP work_gb5rlsphfjehhkepox5hejbplu 47 63 . . . work_gb5rlsphfjehhkepox5hejbplu 48 1 We -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 48 2 report report VBP work_gb5rlsphfjehhkepox5hejbplu 48 3 that that IN work_gb5rlsphfjehhkepox5hejbplu 48 4 , , , work_gb5rlsphfjehhkepox5hejbplu 48 5 in in IN work_gb5rlsphfjehhkepox5hejbplu 48 6 non non JJ work_gb5rlsphfjehhkepox5hejbplu 48 7 - - JJ work_gb5rlsphfjehhkepox5hejbplu 48 8 apoptotic apoptotic JJ work_gb5rlsphfjehhkepox5hejbplu 48 9 pro pro JJ work_gb5rlsphfjehhkepox5hejbplu 48 10 - - JJ work_gb5rlsphfjehhkepox5hejbplu 48 11 lymphocyte lymphocyte JJ work_gb5rlsphfjehhkepox5hejbplu 48 12 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 48 13 , , , work_gb5rlsphfjehhkepox5hejbplu 48 14 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 48 15 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 48 16 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 48 17 induced induce VBD work_gb5rlsphfjehhkepox5hejbplu 48 18 an an DT work_gb5rlsphfjehhkepox5hejbplu 48 19 in- in- JJ work_gb5rlsphfjehhkepox5hejbplu 48 20 crease crease NN work_gb5rlsphfjehhkepox5hejbplu 48 21 of of IN work_gb5rlsphfjehhkepox5hejbplu 48 22 the the DT work_gb5rlsphfjehhkepox5hejbplu 48 23 mitochondrial mitochondrial JJ work_gb5rlsphfjehhkepox5hejbplu 48 24 localization localization NN work_gb5rlsphfjehhkepox5hejbplu 48 25 of of IN work_gb5rlsphfjehhkepox5hejbplu 48 26 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 48 27 up up IN work_gb5rlsphfjehhkepox5hejbplu 48 28 to to IN work_gb5rlsphfjehhkepox5hejbplu 48 29 the the DT work_gb5rlsphfjehhkepox5hejbplu 48 30 level level NN work_gb5rlsphfjehhkepox5hejbplu 48 31 found find VBN work_gb5rlsphfjehhkepox5hejbplu 48 32 in in IN work_gb5rlsphfjehhkepox5hejbplu 48 33 apopto- apopto- PRP$ work_gb5rlsphfjehhkepox5hejbplu 48 34 tic tic JJ work_gb5rlsphfjehhkepox5hejbplu 48 35 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 48 36 . . . work_gb5rlsphfjehhkepox5hejbplu 49 1 Furthermore Furthermore NNP work_gb5rlsphfjehhkepox5hejbplu 49 2 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 49 3 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 49 4 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 49 5 stimulated stimulate VBD work_gb5rlsphfjehhkepox5hejbplu 49 6 both both CC work_gb5rlsphfjehhkepox5hejbplu 49 7 the the DT work_gb5rlsphfjehhkepox5hejbplu 49 8 active active JJ work_gb5rlsphfjehhkepox5hejbplu 49 9 conformation conformation NN work_gb5rlsphfjehhkepox5hejbplu 49 10 of of IN work_gb5rlsphfjehhkepox5hejbplu 49 11 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 49 12 and and CC work_gb5rlsphfjehhkepox5hejbplu 49 13 increased increase VBD work_gb5rlsphfjehhkepox5hejbplu 49 14 the the DT work_gb5rlsphfjehhkepox5hejbplu 49 15 total total JJ work_gb5rlsphfjehhkepox5hejbplu 49 16 amount amount NN work_gb5rlsphfjehhkepox5hejbplu 49 17 of of IN work_gb5rlsphfjehhkepox5hejbplu 49 18 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 49 19 inserted insert VBN work_gb5rlsphfjehhkepox5hejbplu 49 20 in in IN work_gb5rlsphfjehhkepox5hejbplu 49 21 the the DT work_gb5rlsphfjehhkepox5hejbplu 49 22 outer outer JJ work_gb5rlsphfjehhkepox5hejbplu 49 23 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 49 24 mem- mem- NNP work_gb5rlsphfjehhkepox5hejbplu 49 25 brane brane NNP work_gb5rlsphfjehhkepox5hejbplu 49 26 . . . work_gb5rlsphfjehhkepox5hejbplu 50 1 In in IN work_gb5rlsphfjehhkepox5hejbplu 50 2 order order NN work_gb5rlsphfjehhkepox5hejbplu 50 3 to to TO work_gb5rlsphfjehhkepox5hejbplu 50 4 further further RB work_gb5rlsphfjehhkepox5hejbplu 50 5 investigate investigate VB work_gb5rlsphfjehhkepox5hejbplu 50 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 50 7 molecular molecular JJ work_gb5rlsphfjehhkepox5hejbplu 50 8 mechanisms mechanism NNS work_gb5rlsphfjehhkepox5hejbplu 50 9 involved involve VBN work_gb5rlsphfjehhkepox5hejbplu 50 10 in in IN work_gb5rlsphfjehhkepox5hejbplu 50 11 this this DT work_gb5rlsphfjehhkepox5hejbplu 50 12 effect effect NN work_gb5rlsphfjehhkepox5hejbplu 50 13 , , , work_gb5rlsphfjehhkepox5hejbplu 50 14 different different JJ work_gb5rlsphfjehhkepox5hejbplu 50 15 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 50 16 and and CC work_gb5rlsphfjehhkepox5hejbplu 50 17 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 50 18 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 50 19 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 50 20 mutants mutant NNS work_gb5rlsphfjehhkepox5hejbplu 50 21 were be VBD work_gb5rlsphfjehhkepox5hejbplu 50 22 co co VBN work_gb5rlsphfjehhkepox5hejbplu 50 23 - - VBN work_gb5rlsphfjehhkepox5hejbplu 50 24 expressed express VBN work_gb5rlsphfjehhkepox5hejbplu 50 25 in in IN work_gb5rlsphfjehhkepox5hejbplu 50 26 yeast yeast NN work_gb5rlsphfjehhkepox5hejbplu 50 27 . . . work_gb5rlsphfjehhkepox5hejbplu 51 1 We -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 51 2 found find VBD work_gb5rlsphfjehhkepox5hejbplu 51 3 that that IN work_gb5rlsphfjehhkepox5hejbplu 51 4 wild wild JJ work_gb5rlsphfjehhkepox5hejbplu 51 5 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 51 6 type type NN work_gb5rlsphfjehhkepox5hejbplu 51 7 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 51 8 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 51 9 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 51 10 increased increase VBD work_gb5rlsphfjehhkepox5hejbplu 51 11 the the DT work_gb5rlsphfjehhkepox5hejbplu 51 12 mitochondrial mitochondrial JJ work_gb5rlsphfjehhkepox5hejbplu 51 13 localization localization NN work_gb5rlsphfjehhkepox5hejbplu 51 14 of of IN work_gb5rlsphfjehhkepox5hejbplu 51 15 both both CC work_gb5rlsphfjehhkepox5hejbplu 51 16 wild- wild- NN work_gb5rlsphfjehhkepox5hejbplu 51 17 type type NN work_gb5rlsphfjehhkepox5hejbplu 51 18 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 51 19 and and CC work_gb5rlsphfjehhkepox5hejbplu 51 20 of of IN work_gb5rlsphfjehhkepox5hejbplu 51 21 an an DT work_gb5rlsphfjehhkepox5hejbplu 51 22 active active JJ work_gb5rlsphfjehhkepox5hejbplu 51 23 mutant mutant JJ work_gb5rlsphfjehhkepox5hejbplu 51 24 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 51 25 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 51 26 S184D S184D NNP work_gb5rlsphfjehhkepox5hejbplu 51 27 , , , work_gb5rlsphfjehhkepox5hejbplu 51 28 while while IN work_gb5rlsphfjehhkepox5hejbplu 51 29 mutant mutant JJ work_gb5rlsphfjehhkepox5hejbplu 51 30 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 51 31 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 51 32 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 51 33 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 51 34 G138A G138A NNP work_gb5rlsphfjehhkepox5hejbplu 51 35 did do VBD work_gb5rlsphfjehhkepox5hejbplu 51 36 not not RB work_gb5rlsphfjehhkepox5hejbplu 51 37 have have VB work_gb5rlsphfjehhkepox5hejbplu 51 38 this this DT work_gb5rlsphfjehhkepox5hejbplu 51 39 effect effect NN work_gb5rlsphfjehhkepox5hejbplu 51 40 . . . work_gb5rlsphfjehhkepox5hejbplu 52 1 Further further RB work_gb5rlsphfjehhkepox5hejbplu 52 2 , , , work_gb5rlsphfjehhkepox5hejbplu 52 3 wild wild JJ work_gb5rlsphfjehhkepox5hejbplu 52 4 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 52 5 type type NN work_gb5rlsphfjehhkepox5hejbplu 52 6 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 52 7 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 52 8 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 52 9 protected protect VBD work_gb5rlsphfjehhkepox5hejbplu 52 10 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 52 11 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 52 12 S184D S184D NNP work_gb5rlsphfjehhkepox5hejbplu 52 13 against against IN work_gb5rlsphfjehhkepox5hejbplu 52 14 proteolytic proteolytic JJ work_gb5rlsphfjehhkepox5hejbplu 52 15 degradation degradation NN work_gb5rlsphfjehhkepox5hejbplu 52 16 . . . work_gb5rlsphfjehhkepox5hejbplu 53 1 Finally finally RB work_gb5rlsphfjehhkepox5hejbplu 53 2 , , , work_gb5rlsphfjehhkepox5hejbplu 53 3 we -PRON- PRP work_gb5rlsphfjehhkepox5hejbplu 53 4 found find VBD work_gb5rlsphfjehhkepox5hejbplu 53 5 that that IN work_gb5rlsphfjehhkepox5hejbplu 53 6 a a DT work_gb5rlsphfjehhkepox5hejbplu 53 7 C c NN work_gb5rlsphfjehhkepox5hejbplu 53 8 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 53 9 terminally terminally RB work_gb5rlsphfjehhkepox5hejbplu 53 10 truncated truncate VBN work_gb5rlsphfjehhkepox5hejbplu 53 11 mutant mutant NN work_gb5rlsphfjehhkepox5hejbplu 53 12 of of IN work_gb5rlsphfjehhkepox5hejbplu 53 13 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 53 14 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 53 15 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 53 16 , , , work_gb5rlsphfjehhkepox5hejbplu 53 17 that that WDT work_gb5rlsphfjehhkepox5hejbplu 53 18 lost lose VBD work_gb5rlsphfjehhkepox5hejbplu 53 19 its -PRON- PRP$ work_gb5rlsphfjehhkepox5hejbplu 53 20 capacity capacity NN work_gb5rlsphfjehhkepox5hejbplu 53 21 to to TO work_gb5rlsphfjehhkepox5hejbplu 53 22 inhibit inhibit VB work_gb5rlsphfjehhkepox5hejbplu 53 23 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 53 24 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 53 25 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 53 26 release release NN work_gb5rlsphfjehhkepox5hejbplu 53 27 of of IN work_gb5rlsphfjehhkepox5hejbplu 53 28 cyto- cyto- NNS work_gb5rlsphfjehhkepox5hejbplu 53 29 chrome chrome NNP work_gb5rlsphfjehhkepox5hejbplu 53 30 c c NNP work_gb5rlsphfjehhkepox5hejbplu 53 31 , , , work_gb5rlsphfjehhkepox5hejbplu 53 32 still still RB work_gb5rlsphfjehhkepox5hejbplu 53 33 increased increase VBD work_gb5rlsphfjehhkepox5hejbplu 53 34 the the DT work_gb5rlsphfjehhkepox5hejbplu 53 35 mitochondrial mitochondrial JJ work_gb5rlsphfjehhkepox5hejbplu 53 36 localization localization NN work_gb5rlsphfjehhkepox5hejbplu 53 37 of of IN work_gb5rlsphfjehhkepox5hejbplu 53 38 wild wild JJ work_gb5rlsphfjehhkepox5hejbplu 53 39 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 53 40 type type NN work_gb5rlsphfjehhkepox5hejbplu 53 41 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 53 42 , , , work_gb5rlsphfjehhkepox5hejbplu 53 43 thus thus RB work_gb5rlsphfjehhkepox5hejbplu 53 44 promoting promote VBG work_gb5rlsphfjehhkepox5hejbplu 53 45 the the DT work_gb5rlsphfjehhkepox5hejbplu 53 46 release release NN work_gb5rlsphfjehhkepox5hejbplu 53 47 of of IN work_gb5rlsphfjehhkepox5hejbplu 53 48 cytochrome cytochrome DT work_gb5rlsphfjehhkepox5hejbplu 53 49 c. c. NN work_gb5rlsphfjehhkepox5hejbplu 53 50 These these DT work_gb5rlsphfjehhkepox5hejbplu 53 51 data datum NNS work_gb5rlsphfjehhkepox5hejbplu 53 52 suggest suggest VBP work_gb5rlsphfjehhkepox5hejbplu 53 53 that that IN work_gb5rlsphfjehhkepox5hejbplu 53 54 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 53 55 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 53 56 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 53 57 , , , work_gb5rlsphfjehhkepox5hejbplu 53 58 by by IN work_gb5rlsphfjehhkepox5hejbplu 53 59 act- act- NN work_gb5rlsphfjehhkepox5hejbplu 53 60 ing ing NNP work_gb5rlsphfjehhkepox5hejbplu 53 61 as as IN work_gb5rlsphfjehhkepox5hejbplu 53 62 a a DT work_gb5rlsphfjehhkepox5hejbplu 53 63 modulator modulator NN work_gb5rlsphfjehhkepox5hejbplu 53 64 of of IN work_gb5rlsphfjehhkepox5hejbplu 53 65 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 53 66 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 53 67 localization localization NN work_gb5rlsphfjehhkepox5hejbplu 53 68 , , , work_gb5rlsphfjehhkepox5hejbplu 53 69 may may MD work_gb5rlsphfjehhkepox5hejbplu 53 70 play play VB work_gb5rlsphfjehhkepox5hejbplu 53 71 an an DT work_gb5rlsphfjehhkepox5hejbplu 53 72 active active JJ work_gb5rlsphfjehhkepox5hejbplu 53 73 role role NN work_gb5rlsphfjehhkepox5hejbplu 53 74 along along IN work_gb5rlsphfjehhkepox5hejbplu 53 75 the the DT work_gb5rlsphfjehhkepox5hejbplu 53 76 pathway pathway NN work_gb5rlsphfjehhkepox5hejbplu 53 77 leading lead VBG work_gb5rlsphfjehhkepox5hejbplu 53 78 to to IN work_gb5rlsphfjehhkepox5hejbplu 53 79 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 53 80 activation activation NN work_gb5rlsphfjehhkepox5hejbplu 53 81 . . . work_gb5rlsphfjehhkepox5hejbplu 54 1 2220-Plat 2220-plat CD work_gb5rlsphfjehhkepox5hejbplu 54 2 The the DT work_gb5rlsphfjehhkepox5hejbplu 54 3 Physiological physiological JJ work_gb5rlsphfjehhkepox5hejbplu 54 4 Response response NN work_gb5rlsphfjehhkepox5hejbplu 54 5 of of IN work_gb5rlsphfjehhkepox5hejbplu 54 6 Intact intact JJ work_gb5rlsphfjehhkepox5hejbplu 54 7 Ex Ex NNP work_gb5rlsphfjehhkepox5hejbplu 54 8 Vivo Vivo NNP work_gb5rlsphfjehhkepox5hejbplu 54 9 Mitochondria Mitochondria NNP work_gb5rlsphfjehhkepox5hejbplu 54 10 upon upon IN work_gb5rlsphfjehhkepox5hejbplu 54 11 Apopto- Apopto- NNP work_gb5rlsphfjehhkepox5hejbplu 54 12 tic tic JJ work_gb5rlsphfjehhkepox5hejbplu 54 13 Stress stress NN work_gb5rlsphfjehhkepox5hejbplu 54 14 : : : work_gb5rlsphfjehhkepox5hejbplu 54 15 Insight insight NN work_gb5rlsphfjehhkepox5hejbplu 54 16 into into IN work_gb5rlsphfjehhkepox5hejbplu 54 17 the the DT work_gb5rlsphfjehhkepox5hejbplu 54 18 Regulation regulation NN work_gb5rlsphfjehhkepox5hejbplu 54 19 of of IN work_gb5rlsphfjehhkepox5hejbplu 54 20 Apoptosis Apoptosis NNP work_gb5rlsphfjehhkepox5hejbplu 54 21 at at IN work_gb5rlsphfjehhkepox5hejbplu 54 22 a a DT work_gb5rlsphfjehhkepox5hejbplu 54 23 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 54 24 Level Level NNP work_gb5rlsphfjehhkepox5hejbplu 54 25 Martin Martin NNP work_gb5rlsphfjehhkepox5hejbplu 54 26 N. N. NNP work_gb5rlsphfjehhkepox5hejbplu 54 27 Lidman1 Lidman1 NNP work_gb5rlsphfjehhkepox5hejbplu 54 28 , , , work_gb5rlsphfjehhkepox5hejbplu 54 29 Marcus Marcus NNP work_gb5rlsphfjehhkepox5hejbplu 54 30 Wallgren1 Wallgren1 NNP work_gb5rlsphfjehhkepox5hejbplu 54 31 , , , work_gb5rlsphfjehhkepox5hejbplu 54 32 Olivier Olivier NNP work_gb5rlsphfjehhkepox5hejbplu 54 33 Keech2 Keech2 NNP work_gb5rlsphfjehhkepox5hejbplu 54 34 , , , work_gb5rlsphfjehhkepox5hejbplu 54 35 Yong Yong NNP work_gb5rlsphfjehhkepox5hejbplu 54 36 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 54 37 Zhi Zhi NNP work_gb5rlsphfjehhkepox5hejbplu 54 38 Guo3 Guo3 NNP work_gb5rlsphfjehhkepox5hejbplu 54 39 , , , work_gb5rlsphfjehhkepox5hejbplu 54 40 Tor tor NN work_gb5rlsphfjehhkepox5hejbplu 54 41 Ny3 ny3 NN work_gb5rlsphfjehhkepox5hejbplu 54 42 , , , work_gb5rlsphfjehhkepox5hejbplu 54 43 Gerhard Gerhard NNP work_gb5rlsphfjehhkepox5hejbplu 54 44 Gröbner1 Gröbner1 NNS work_gb5rlsphfjehhkepox5hejbplu 54 45 . . . work_gb5rlsphfjehhkepox5hejbplu 55 1 1Chemistry 1Chemistry NNP work_gb5rlsphfjehhkepox5hejbplu 55 2 Department Department NNP work_gb5rlsphfjehhkepox5hejbplu 55 3 , , , work_gb5rlsphfjehhkepox5hejbplu 55 4 Umeå Umeå NNP work_gb5rlsphfjehhkepox5hejbplu 55 5 University University NNP work_gb5rlsphfjehhkepox5hejbplu 55 6 , , , work_gb5rlsphfjehhkepox5hejbplu 55 7 Umeå Umeå NNP work_gb5rlsphfjehhkepox5hejbplu 55 8 , , , work_gb5rlsphfjehhkepox5hejbplu 55 9 Sweden Sweden NNP work_gb5rlsphfjehhkepox5hejbplu 55 10 , , , work_gb5rlsphfjehhkepox5hejbplu 55 11 2Umeå 2umeå CD work_gb5rlsphfjehhkepox5hejbplu 55 12 Plant Plant NNP work_gb5rlsphfjehhkepox5hejbplu 55 13 Science Science NNP work_gb5rlsphfjehhkepox5hejbplu 55 14 Center Center NNP work_gb5rlsphfjehhkepox5hejbplu 55 15 , , , work_gb5rlsphfjehhkepox5hejbplu 55 16 Umeå umeå UH work_gb5rlsphfjehhkepox5hejbplu 55 17 , , , work_gb5rlsphfjehhkepox5hejbplu 55 18 Sweden Sweden NNP work_gb5rlsphfjehhkepox5hejbplu 55 19 , , , work_gb5rlsphfjehhkepox5hejbplu 55 20 3 3 CD work_gb5rlsphfjehhkepox5hejbplu 55 21 Medical Medical NNP work_gb5rlsphfjehhkepox5hejbplu 55 22 Chemistry Chemistry NNP work_gb5rlsphfjehhkepox5hejbplu 55 23 and and CC work_gb5rlsphfjehhkepox5hejbplu 55 24 Biophysics Biophysics NNPS work_gb5rlsphfjehhkepox5hejbplu 55 25 , , , work_gb5rlsphfjehhkepox5hejbplu 55 26 Umeå Umeå NNP work_gb5rlsphfjehhkepox5hejbplu 55 27 University University NNP work_gb5rlsphfjehhkepox5hejbplu 55 28 , , , work_gb5rlsphfjehhkepox5hejbplu 55 29 Umeå Umeå NNP work_gb5rlsphfjehhkepox5hejbplu 55 30 , , , work_gb5rlsphfjehhkepox5hejbplu 55 31 Sweden Sweden NNP work_gb5rlsphfjehhkepox5hejbplu 55 32 . . . work_gb5rlsphfjehhkepox5hejbplu 56 1 Apoptosis apoptosis NN work_gb5rlsphfjehhkepox5hejbplu 56 2 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 56 3 programmed program VBN work_gb5rlsphfjehhkepox5hejbplu 56 4 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 56 5 death death NN work_gb5rlsphfjehhkepox5hejbplu 56 6 - - : work_gb5rlsphfjehhkepox5hejbplu 56 7 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 56 8 vital vital JJ work_gb5rlsphfjehhkepox5hejbplu 56 9 for for IN work_gb5rlsphfjehhkepox5hejbplu 56 10 multicellular multicellular JJ work_gb5rlsphfjehhkepox5hejbplu 56 11 organisms organism NNS work_gb5rlsphfjehhkepox5hejbplu 56 12 to to TO work_gb5rlsphfjehhkepox5hejbplu 56 13 dis- dis- VB work_gb5rlsphfjehhkepox5hejbplu 56 14 pose pose NN work_gb5rlsphfjehhkepox5hejbplu 56 15 of of IN work_gb5rlsphfjehhkepox5hejbplu 56 16 redundant redundant JJ work_gb5rlsphfjehhkepox5hejbplu 56 17 , , , work_gb5rlsphfjehhkepox5hejbplu 56 18 damaged damage VBN work_gb5rlsphfjehhkepox5hejbplu 56 19 or or CC work_gb5rlsphfjehhkepox5hejbplu 56 20 infected infected JJ work_gb5rlsphfjehhkepox5hejbplu 56 21 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 56 22 . . . work_gb5rlsphfjehhkepox5hejbplu 57 1 This this DT work_gb5rlsphfjehhkepox5hejbplu 57 2 mechanism mechanism NN work_gb5rlsphfjehhkepox5hejbplu 57 3 becomes become VBZ work_gb5rlsphfjehhkepox5hejbplu 57 4 dys- dys- NNP work_gb5rlsphfjehhkepox5hejbplu 57 5 functional functional JJ work_gb5rlsphfjehhkepox5hejbplu 57 6 in in IN work_gb5rlsphfjehhkepox5hejbplu 57 7 cancer cancer NN work_gb5rlsphfjehhkepox5hejbplu 57 8 where where WRB work_gb5rlsphfjehhkepox5hejbplu 57 9 tumor tumor NN work_gb5rlsphfjehhkepox5hejbplu 57 10 cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 57 11 survive survive VBP work_gb5rlsphfjehhkepox5hejbplu 57 12 drug drug NN work_gb5rlsphfjehhkepox5hejbplu 57 13 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 57 14 induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 57 15 death death NN work_gb5rlsphfjehhkepox5hejbplu 57 16 signals signal NNS work_gb5rlsphfjehhkepox5hejbplu 57 17 . . . work_gb5rlsphfjehhkepox5hejbplu 58 1 Reversely reversely RB work_gb5rlsphfjehhkepox5hejbplu 58 2 , , , work_gb5rlsphfjehhkepox5hejbplu 58 3 upregulated upregulated JJ work_gb5rlsphfjehhkepox5hejbplu 58 4 apoptosis apoptosis NN work_gb5rlsphfjehhkepox5hejbplu 58 5 can can MD work_gb5rlsphfjehhkepox5hejbplu 58 6 induce induce VB work_gb5rlsphfjehhkepox5hejbplu 58 7 premature premature JJ work_gb5rlsphfjehhkepox5hejbplu 58 8 neuronal neuronal JJ work_gb5rlsphfjehhkepox5hejbplu 58 9 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 58 10 death death NN work_gb5rlsphfjehhkepox5hejbplu 58 11 in in IN work_gb5rlsphfjehhkepox5hejbplu 58 12 amyloidogenic amyloidogenic JJ work_gb5rlsphfjehhkepox5hejbplu 58 13 diseases disease NNS work_gb5rlsphfjehhkepox5hejbplu 58 14 such such JJ work_gb5rlsphfjehhkepox5hejbplu 58 15 as as IN work_gb5rlsphfjehhkepox5hejbplu 58 16 Alzheimer Alzheimer NNP work_gb5rlsphfjehhkepox5hejbplu 58 17 ’s ’s POS work_gb5rlsphfjehhkepox5hejbplu 58 18 disease disease NN work_gb5rlsphfjehhkepox5hejbplu 58 19 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 58 20 AD ad NN work_gb5rlsphfjehhkepox5hejbplu 58 21 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 58 22 or or CC work_gb5rlsphfjehhkepox5hejbplu 58 23 Amyotrophic Amyotrophic NNP work_gb5rlsphfjehhkepox5hejbplu 58 24 Lateral Lateral NNP work_gb5rlsphfjehhkepox5hejbplu 58 25 Sclerosis Sclerosis NNP work_gb5rlsphfjehhkepox5hejbplu 58 26 ( ( -LRB- work_gb5rlsphfjehhkepox5hejbplu 58 27 ALS ALS NNP work_gb5rlsphfjehhkepox5hejbplu 58 28 ) ) -RRB- work_gb5rlsphfjehhkepox5hejbplu 58 29 . . . work_gb5rlsphfjehhkepox5hejbplu 59 1 Mitochondrion mitochondrion NN work_gb5rlsphfjehhkepox5hejbplu 59 2 , , , work_gb5rlsphfjehhkepox5hejbplu 59 3 the the DT work_gb5rlsphfjehhkepox5hejbplu 59 4 power power NN work_gb5rlsphfjehhkepox5hejbplu 59 5 plant plant NN work_gb5rlsphfjehhkepox5hejbplu 59 6 of of IN work_gb5rlsphfjehhkepox5hejbplu 59 7 the the DT work_gb5rlsphfjehhkepox5hejbplu 59 8 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 59 9 , , , work_gb5rlsphfjehhkepox5hejbplu 59 10 contains contain VBZ work_gb5rlsphfjehhkepox5hejbplu 59 11 an an DT work_gb5rlsphfjehhkepox5hejbplu 59 12 arsenal arsenal NN work_gb5rlsphfjehhkepox5hejbplu 59 13 of of IN work_gb5rlsphfjehhkepox5hejbplu 59 14 proteins protein NNS work_gb5rlsphfjehhkepox5hejbplu 59 15 which which WDT work_gb5rlsphfjehhkepox5hejbplu 59 16 regulate regulate VBP work_gb5rlsphfjehhkepox5hejbplu 59 17 programmed program VBD work_gb5rlsphfjehhkepox5hejbplu 59 18 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 59 19 death death NN work_gb5rlsphfjehhkepox5hejbplu 59 20 . . . work_gb5rlsphfjehhkepox5hejbplu 60 1 There there RB work_gb5rlsphfjehhkepox5hejbplu 60 2 , , , work_gb5rlsphfjehhkepox5hejbplu 60 3 the the DT work_gb5rlsphfjehhkepox5hejbplu 60 4 pro- pro- NN work_gb5rlsphfjehhkepox5hejbplu 60 5 and and CC work_gb5rlsphfjehhkepox5hejbplu 60 6 anti anti JJ work_gb5rlsphfjehhkepox5hejbplu 60 7 - - JJ work_gb5rlsphfjehhkepox5hejbplu 60 8 apoptotic apoptotic JJ work_gb5rlsphfjehhkepox5hejbplu 60 9 Bcl-2 Bcl-2 NNP work_gb5rlsphfjehhkepox5hejbplu 60 10 proteins protein NNS work_gb5rlsphfjehhkepox5hejbplu 60 11 meet meet VBP work_gb5rlsphfjehhkepox5hejbplu 60 12 at at IN work_gb5rlsphfjehhkepox5hejbplu 60 13 the the DT work_gb5rlsphfjehhkepox5hejbplu 60 14 mitochondrial mitochondrial NN work_gb5rlsphfjehhkepox5hejbplu 60 15 membrane membrane NN work_gb5rlsphfjehhkepox5hejbplu 60 16 to to TO work_gb5rlsphfjehhkepox5hejbplu 60 17 decide decide VB work_gb5rlsphfjehhkepox5hejbplu 60 18 the the DT work_gb5rlsphfjehhkepox5hejbplu 60 19 fate fate NN work_gb5rlsphfjehhkepox5hejbplu 60 20 of of IN work_gb5rlsphfjehhkepox5hejbplu 60 21 a a DT work_gb5rlsphfjehhkepox5hejbplu 60 22 cell cell NN work_gb5rlsphfjehhkepox5hejbplu 60 23 . . . work_gb5rlsphfjehhkepox5hejbplu 61 1 How how WRB work_gb5rlsphfjehhkepox5hejbplu 61 2 the the DT work_gb5rlsphfjehhkepox5hejbplu 61 3 molecular molecular JJ work_gb5rlsphfjehhkepox5hejbplu 61 4 activities activity NNS work_gb5rlsphfjehhkepox5hejbplu 61 5 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 6 the the DT work_gb5rlsphfjehhkepox5hejbplu 61 7 anti anti JJ work_gb5rlsphfjehhkepox5hejbplu 61 8 - - JJ work_gb5rlsphfjehhkepox5hejbplu 61 9 apoptotic apoptotic JJ work_gb5rlsphfjehhkepox5hejbplu 61 10 The the DT work_gb5rlsphfjehhkepox5hejbplu 61 11 Isoform Isoform NNP work_gb5rlsphfjehhkepox5hejbplu 61 12 Specific Specific NNP work_gb5rlsphfjehhkepox5hejbplu 61 13 N N NNP work_gb5rlsphfjehhkepox5hejbplu 61 14 Terminus Terminus NNP work_gb5rlsphfjehhkepox5hejbplu 61 15 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 16 VDAC2 VDAC2 NNP work_gb5rlsphfjehhkepox5hejbplu 61 17 is be VBZ work_gb5rlsphfjehhkepox5hejbplu 61 18 Dispensable dispensable JJ work_gb5rlsphfjehhkepox5hejbplu 61 19 for for IN work_gb5rlsphfjehhkepox5hejbplu 61 20 tBid tBid NNP work_gb5rlsphfjehhkepox5hejbplu 61 21 Induced induce VBN work_gb5rlsphfjehhkepox5hejbplu 61 22 Cytochrome Cytochrome NNP work_gb5rlsphfjehhkepox5hejbplu 61 23 C C NNP work_gb5rlsphfjehhkepox5hejbplu 61 24 Release Release NNP work_gb5rlsphfjehhkepox5hejbplu 61 25 Patch Patch NNP work_gb5rlsphfjehhkepox5hejbplu 61 26 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 61 27 Clamp Clamp NNP work_gb5rlsphfjehhkepox5hejbplu 61 28 Analysis Analysis NNP work_gb5rlsphfjehhkepox5hejbplu 61 29 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 30 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 61 31 Ca2 ca2 NN work_gb5rlsphfjehhkepox5hejbplu 61 32 + + SYM work_gb5rlsphfjehhkepox5hejbplu 61 33 Uniporter Uniporter NNP work_gb5rlsphfjehhkepox5hejbplu 61 34 in in IN work_gb5rlsphfjehhkepox5hejbplu 61 35 Different Different NNP work_gb5rlsphfjehhkepox5hejbplu 61 36 Tissues Tissues NNPS work_gb5rlsphfjehhkepox5hejbplu 61 37 SR SR NNP work_gb5rlsphfjehhkepox5hejbplu 61 38 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 61 39 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 61 40 Ultrastructure Ultrastructure NNP work_gb5rlsphfjehhkepox5hejbplu 61 41 in in IN work_gb5rlsphfjehhkepox5hejbplu 61 42 the the DT work_gb5rlsphfjehhkepox5hejbplu 61 43 Heart heart NN work_gb5rlsphfjehhkepox5hejbplu 61 44 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 45 Normal Normal NNP work_gb5rlsphfjehhkepox5hejbplu 61 46 and and CC work_gb5rlsphfjehhkepox5hejbplu 61 47 Ethanol Ethanol NNP work_gb5rlsphfjehhkepox5hejbplu 61 48 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 61 49 Fed Fed NNP work_gb5rlsphfjehhkepox5hejbplu 61 50 Rats Rats NNP work_gb5rlsphfjehhkepox5hejbplu 61 51 Bcl Bcl NNP work_gb5rlsphfjehhkepox5hejbplu 61 52 - - HYPH work_gb5rlsphfjehhkepox5hejbplu 61 53 xL xL NNP work_gb5rlsphfjehhkepox5hejbplu 61 54 Increases Increases NNPS work_gb5rlsphfjehhkepox5hejbplu 61 55 Bax Bax NNP work_gb5rlsphfjehhkepox5hejbplu 61 56 Mitochondrial Mitochondrial NNP work_gb5rlsphfjehhkepox5hejbplu 61 57 Localization Localization NNP work_gb5rlsphfjehhkepox5hejbplu 61 58 and and CC work_gb5rlsphfjehhkepox5hejbplu 61 59 Activation Activation NNP work_gb5rlsphfjehhkepox5hejbplu 61 60 in in IN work_gb5rlsphfjehhkepox5hejbplu 61 61 Non non JJ work_gb5rlsphfjehhkepox5hejbplu 61 62 - - JJ work_gb5rlsphfjehhkepox5hejbplu 61 63 Apoptotic apoptotic JJ work_gb5rlsphfjehhkepox5hejbplu 61 64 Cells cell NNS work_gb5rlsphfjehhkepox5hejbplu 61 65 The the DT work_gb5rlsphfjehhkepox5hejbplu 61 66 Physiological physiological JJ work_gb5rlsphfjehhkepox5hejbplu 61 67 Response response NN work_gb5rlsphfjehhkepox5hejbplu 61 68 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 69 Intact intact JJ work_gb5rlsphfjehhkepox5hejbplu 61 70 Ex Ex NNP work_gb5rlsphfjehhkepox5hejbplu 61 71 Vivo Vivo NNP work_gb5rlsphfjehhkepox5hejbplu 61 72 Mitochondria Mitochondria NNP work_gb5rlsphfjehhkepox5hejbplu 61 73 upon upon IN work_gb5rlsphfjehhkepox5hejbplu 61 74 Apoptotic Apoptotic NNP work_gb5rlsphfjehhkepox5hejbplu 61 75 Stress Stress NNP work_gb5rlsphfjehhkepox5hejbplu 61 76 : : : work_gb5rlsphfjehhkepox5hejbplu 61 77 Insight insight NN work_gb5rlsphfjehhkepox5hejbplu 61 78 into into IN work_gb5rlsphfjehhkepox5hejbplu 61 79 the the DT work_gb5rlsphfjehhkepox5hejbplu 61 80 Regulation Regulation NNP work_gb5rlsphfjehhkepox5hejbplu 61 81 of of IN work_gb5rlsphfjehhkepox5hejbplu 61 82 Apoptosis Apoptosis NNP work_gb5rlsphfjehhkepox5hejbplu 61 83 a a NN work_gb5rlsphfjehhkepox5hejbplu 61 84 ... ... .