id	sid	tid	token	lemma	pos
work_icsipe3itza57oc7ahgvt4fxwi	1	1	MICU1-dependent	MICU1-dependent	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	2	Threshold	Threshold	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	3	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	1	4	Cooperativity	Cooperativity	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	1	6	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	7	Ca2	ca2	NN
work_icsipe3itza57oc7ahgvt4fxwi	1	8	+	+	CC
work_icsipe3itza57oc7ahgvt4fxwi	1	9	Uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	1	10	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	1	11	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	1	12	Liver	Liver	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	13	Wednesday	Wednesday	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	14	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	15	February	February	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	16	6	6	CD
work_icsipe3itza57oc7ahgvt4fxwi	1	17	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	18	2013	2013	CD
work_icsipe3itza57oc7ahgvt4fxwi	1	19	655a	655a	IN
work_icsipe3itza57oc7ahgvt4fxwi	1	20	Mitochondria	Mitochondria	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	21	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	1	22	Cell	Cell	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	23	Life	Life	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	24	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	1	25	Death	Death	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	26	3363-Pos	3363-Pos	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	27	Board	Board	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	28	B518	B518	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	29	A	A	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	30	Step	Step	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	31	Forwardin	Forwardin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	32	Understanding	understand	VBG
work_icsipe3itza57oc7ahgvt4fxwi	1	33	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	1	34	Mechanismof	Mechanismof	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	35	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	36	Voltage	Voltage	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	37	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	1	38	Gating	Gating	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	39	Oscar	Oscar	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	40	Teijido	Teijido	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	41	Hermida1	Hermida1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	42	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	43	Shay	Shay	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	44	Rappaport1	Rappaport1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	45	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	46	Rachna	Rachna	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	47	Ujwal2	Ujwal2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	48	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	49	Jeff	Jeff	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	50	Abramson2	Abramson2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	51	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	52	Vicente	Vicente	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	53	M.	M.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	54	Aguilella3	Aguilella3	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	55	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	56	Sergey	Sergey	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	57	M.	M.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	58	Bezrukov1	Bezrukov1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	59	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	1	60	Tatiana	Tatiana	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	61	K.	K.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	62	Rostovtseva1	Rostovtseva1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	1	63	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	2	1	1NICHD	1nichd	CD
work_icsipe3itza57oc7ahgvt4fxwi	2	2	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	3	National	National	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	4	Institutes	Institutes	NNPS
work_icsipe3itza57oc7ahgvt4fxwi	2	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	2	6	Health	Health	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	7	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	2	8	NIH	NIH	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	9	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	2	10	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	11	Bethesda	Bethesda	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	12	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	13	MD	MD	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	14	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	15	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	16	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	17	2David	2david	CD
work_icsipe3itza57oc7ahgvt4fxwi	2	18	Geffen	Geffen	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	19	School	School	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	20	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	2	21	Medicine	Medicine	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	22	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	23	UCLA	UCLA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	24	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	25	Los	Los	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	26	Angeles	Angeles	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	27	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	28	CA	CA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	29	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	30	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	31	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	32	3	3	CD
work_icsipe3itza57oc7ahgvt4fxwi	2	33	Universitat	Universitat	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	34	Jaume	Jaume	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	35	I	I	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	36	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	37	Castello	Castello	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	38	de	de	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	39	la	la	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	40	Plana	Plana	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	41	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	2	42	Spain	Spain	NNP
work_icsipe3itza57oc7ahgvt4fxwi	2	43	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	3	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	3	2	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	3	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	3	4	dependent	dependent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	3	5	anion	anion	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	6	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	7	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	3	8	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	3	9	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	3	10	governs	govern	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	3	11	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	3	12	exchange	exchange	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	13	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	3	14	ions	ion	NNS
work_icsipe3itza57oc7ahgvt4fxwi	3	15	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	3	16	metabolites	metabolite	NNS
work_icsipe3itza57oc7ahgvt4fxwi	3	17	between	between	IN
work_icsipe3itza57oc7ahgvt4fxwi	3	18	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	3	19	mitochondria	mitochondrion	NNS
work_icsipe3itza57oc7ahgvt4fxwi	3	20	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	3	21	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	3	22	rest	rest	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	23	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	3	24	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	3	25	cell	cell	NN
work_icsipe3itza57oc7ahgvt4fxwi	3	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	4	1	In	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	4	2	its	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	4	3	open	open	JJ
work_icsipe3itza57oc7ahgvt4fxwi	4	4	state	state	NN
work_icsipe3itza57oc7ahgvt4fxwi	4	5	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	4	6	exhibits	exhibit	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	4	7	high	high	JJ
work_icsipe3itza57oc7ahgvt4fxwi	4	8	conductance	conductance	NN
work_icsipe3itza57oc7ahgvt4fxwi	4	9	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	4	10	selectivity	selectivity	NN
work_icsipe3itza57oc7ahgvt4fxwi	4	11	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	4	12	anions	anion	NNS
work_icsipe3itza57oc7ahgvt4fxwi	4	13	that	that	WDT
work_icsipe3itza57oc7ahgvt4fxwi	4	14	facilitates	facilitate	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	4	15	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	4	16	passage	passage	NN
work_icsipe3itza57oc7ahgvt4fxwi	4	17	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	4	18	ADP	ADP	NNP
work_icsipe3itza57oc7ahgvt4fxwi	4	19	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	4	20	ATP	ATP	NNP
work_icsipe3itza57oc7ahgvt4fxwi	4	21	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	4	22	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	4	23	other	other	JJ
work_icsipe3itza57oc7ahgvt4fxwi	4	24	metabolites	metabolite	NNS
work_icsipe3itza57oc7ahgvt4fxwi	4	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	5	1	At	at	IN
work_icsipe3itza57oc7ahgvt4fxwi	5	2	increased	increased	JJ
work_icsipe3itza57oc7ahgvt4fxwi	5	3	voltages	voltage	NNS
work_icsipe3itza57oc7ahgvt4fxwi	5	4	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	5	5	>	>	XX
work_icsipe3itza57oc7ahgvt4fxwi	5	6	30mV	30mv	CD
work_icsipe3itza57oc7ahgvt4fxwi	5	7	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	5	8	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	5	9	switches	switch	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	5	10	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	5	11	lower	lower	VB
work_icsipe3itza57oc7ahgvt4fxwi	5	12	conducting	conduct	VBG
work_icsipe3itza57oc7ahgvt4fxwi	5	13	states	state	NNS
work_icsipe3itza57oc7ahgvt4fxwi	5	14	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	5	15	termed	term	VBD
work_icsipe3itza57oc7ahgvt4fxwi	5	16	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	5	17	‘	'	``
work_icsipe3itza57oc7ahgvt4fxwi	5	18	‘	'	``
work_icsipe3itza57oc7ahgvt4fxwi	5	19	closed	close	VBN
work_icsipe3itza57oc7ahgvt4fxwi	5	20	’	'	''
work_icsipe3itza57oc7ahgvt4fxwi	5	21	’	'	''
work_icsipe3itza57oc7ahgvt4fxwi	5	22	states	state	NNS
work_icsipe3itza57oc7ahgvt4fxwi	5	23	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	6	1	Closed	closed	JJ
work_icsipe3itza57oc7ahgvt4fxwi	6	2	states	state	NNS
work_icsipe3itza57oc7ahgvt4fxwi	6	3	are	be	VBP
work_icsipe3itza57oc7ahgvt4fxwi	6	4	cation	cation	NN
work_icsipe3itza57oc7ahgvt4fxwi	6	5	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	6	6	selective	selective	JJ
work_icsipe3itza57oc7ahgvt4fxwi	6	7	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	6	8	impermeable	impermeable	JJ
work_icsipe3itza57oc7ahgvt4fxwi	6	9	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	6	10	ATP	ATP	NNP
work_icsipe3itza57oc7ahgvt4fxwi	6	11	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	7	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	7	2	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	7	3	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	7	4	induced	induce	VBN
work_icsipe3itza57oc7ahgvt4fxwi	7	5	transition	transition	NN
work_icsipe3itza57oc7ahgvt4fxwi	7	6	from	from	IN
work_icsipe3itza57oc7ahgvt4fxwi	7	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	7	8	open	open	JJ
work_icsipe3itza57oc7ahgvt4fxwi	7	9	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	7	10	closed	close	VBN
work_icsipe3itza57oc7ahgvt4fxwi	7	11	states	state	NNS
work_icsipe3itza57oc7ahgvt4fxwi	7	12	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	7	13	referred	refer	VBN
work_icsipe3itza57oc7ahgvt4fxwi	7	14	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	7	15	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	7	16	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	7	17	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	7	18	gating	gating	NN
work_icsipe3itza57oc7ahgvt4fxwi	7	19	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	8	1	Although	although	IN
work_icsipe3itza57oc7ahgvt4fxwi	8	2	it	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	8	3	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	8	4	well	well	RB
work_icsipe3itza57oc7ahgvt4fxwi	8	5	established	establish	VBN
work_icsipe3itza57oc7ahgvt4fxwi	8	6	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	8	7	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	8	8	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	8	9	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	8	10	gating	gate	VBG
work_icsipe3itza57oc7ahgvt4fxwi	8	11	in-	in-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	8	12	volves	volve	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	8	13	large	large	JJ
work_icsipe3itza57oc7ahgvt4fxwi	8	14	structural	structural	JJ
work_icsipe3itza57oc7ahgvt4fxwi	8	15	rearrangements	rearrangement	NNS
work_icsipe3itza57oc7ahgvt4fxwi	8	16	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	8	17	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	8	18	precise	precise	JJ
work_icsipe3itza57oc7ahgvt4fxwi	8	19	molecular	molecular	JJ
work_icsipe3itza57oc7ahgvt4fxwi	8	20	mechanism	mechanism	NN
work_icsipe3itza57oc7ahgvt4fxwi	8	21	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	8	22	this	this	DT
work_icsipe3itza57oc7ahgvt4fxwi	8	23	process	process	NN
work_icsipe3itza57oc7ahgvt4fxwi	8	24	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	8	25	still	still	RB
work_icsipe3itza57oc7ahgvt4fxwi	8	26	under	under	IN
work_icsipe3itza57oc7ahgvt4fxwi	8	27	debate	debate	NN
work_icsipe3itza57oc7ahgvt4fxwi	8	28	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	9	1	We	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	9	2	investigated	investigate	VBD
work_icsipe3itza57oc7ahgvt4fxwi	9	3	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	9	4	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	9	5	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	9	6	gating	gating	JJ
work_icsipe3itza57oc7ahgvt4fxwi	9	7	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	9	8	sys-	sys-	RB
work_icsipe3itza57oc7ahgvt4fxwi	9	9	tematically	tematically	RB
work_icsipe3itza57oc7ahgvt4fxwi	9	10	titrating	titrate	VBG
work_icsipe3itza57oc7ahgvt4fxwi	9	11	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	9	12	charge	charge	NN
work_icsipe3itza57oc7ahgvt4fxwi	9	13	residues	residue	NNS
work_icsipe3itza57oc7ahgvt4fxwi	9	14	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	9	15	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	9	16	using	use	VBG
work_icsipe3itza57oc7ahgvt4fxwi	9	17	thermodynamic	thermodynamic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	9	18	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	9	19	kinetic	kinetic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	9	20	approaches	approach	NNS
work_icsipe3itza57oc7ahgvt4fxwi	9	21	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	9	22	study	study	VB
work_icsipe3itza57oc7ahgvt4fxwi	9	23	opening	opening	NN
work_icsipe3itza57oc7ahgvt4fxwi	9	24	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	9	25	closing	closing	NN
work_icsipe3itza57oc7ahgvt4fxwi	9	26	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	9	27	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	9	28	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	9	29	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	10	1	All	all	PDT
work_icsipe3itza57oc7ahgvt4fxwi	10	2	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	10	3	models	model	NNS
work_icsipe3itza57oc7ahgvt4fxwi	10	4	proposed	propose	VBN
work_icsipe3itza57oc7ahgvt4fxwi	10	5	so	so	RB
work_icsipe3itza57oc7ahgvt4fxwi	10	6	far	far	RB
work_icsipe3itza57oc7ahgvt4fxwi	10	7	agree	agree	VBP
work_icsipe3itza57oc7ahgvt4fxwi	10	8	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	10	9	N	n	CD
work_icsipe3itza57oc7ahgvt4fxwi	10	10	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	10	11	terminal	terminal	NN
work_icsipe3itza57oc7ahgvt4fxwi	10	12	region	region	NN
work_icsipe3itza57oc7ahgvt4fxwi	10	13	plays	play	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	10	14	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	10	15	key	key	JJ
work_icsipe3itza57oc7ahgvt4fxwi	10	16	role	role	NN
work_icsipe3itza57oc7ahgvt4fxwi	10	17	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	10	18	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	10	19	voltage-	voltage-	NNP
work_icsipe3itza57oc7ahgvt4fxwi	10	20	gating	gating	NN
work_icsipe3itza57oc7ahgvt4fxwi	10	21	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	11	1	According	accord	VBG
work_icsipe3itza57oc7ahgvt4fxwi	11	2	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	3	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	4	original	original	JJ
work_icsipe3itza57oc7ahgvt4fxwi	11	5	idea	idea	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	6	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	11	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	8	N	N	NNP
work_icsipe3itza57oc7ahgvt4fxwi	11	9	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	11	10	terminal	terminal	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	11	region	region	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	12	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	11	13	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	14	part	part	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	15	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	16	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	17	mo-	mo-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	11	18	bile	bile	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	19	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	20	sensor	sensor	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	21	domain	domain	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	22	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	11	23	which	which	WDT
work_icsipe3itza57oc7ahgvt4fxwi	11	24	slides	slide	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	11	25	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	26	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	11	27	out	out	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	28	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	29	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	30	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	31	lumen	luman	NNS
work_icsipe3itza57oc7ahgvt4fxwi	11	32	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	33	re-	re-	RB
work_icsipe3itza57oc7ahgvt4fxwi	11	34	sponse	sponse	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	35	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	11	36	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	11	37	applied	apply	VBN
work_icsipe3itza57oc7ahgvt4fxwi	11	38	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	11	39	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	12	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	12	2	alternative	alternative	JJ
work_icsipe3itza57oc7ahgvt4fxwi	12	3	models	model	NNS
work_icsipe3itza57oc7ahgvt4fxwi	12	4	consider	consider	VBP
work_icsipe3itza57oc7ahgvt4fxwi	12	5	independent	independent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	12	6	movement	movement	NN
work_icsipe3itza57oc7ahgvt4fxwi	12	7	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	12	8	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	12	9	N	N	NNP
work_icsipe3itza57oc7ahgvt4fxwi	12	10	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	12	11	terminal	terminal	NN
work_icsipe3itza57oc7ahgvt4fxwi	12	12	region	region	NN
work_icsipe3itza57oc7ahgvt4fxwi	12	13	upon	upon	IN
work_icsipe3itza57oc7ahgvt4fxwi	12	14	gating	gate	VBG
work_icsipe3itza57oc7ahgvt4fxwi	12	15	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	13	1	In	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	2	order	order	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	3	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	13	4	test	test	VB
work_icsipe3itza57oc7ahgvt4fxwi	13	5	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	6	role	role	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	7	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	8	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	9	N	N	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	10	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	13	11	terminal	terminal	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	12	region	region	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	13	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	14	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	15	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	13	16	gating	gate	VBG
work_icsipe3itza57oc7ahgvt4fxwi	13	17	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	13	18	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	13	19	engineered	engineer	VBD
work_icsipe3itza57oc7ahgvt4fxwi	13	20	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	21	double	double	JJ
work_icsipe3itza57oc7ahgvt4fxwi	13	22	Cys	Cys	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	23	mu-	mu-	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	24	tant	tant	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	25	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	26	murine	murine	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	27	VDAC1	VDAC1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	28	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	29	cross	cross	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	30	-	-	NNS
work_icsipe3itza57oc7ahgvt4fxwi	13	31	links	link	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	13	32	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	33	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	34	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	13	35	helix	helix	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	36	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	37	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	38	b	b	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	39	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	13	40	strand	strand	NNP
work_icsipe3itza57oc7ahgvt4fxwi	13	41	11	11	CD
work_icsipe3itza57oc7ahgvt4fxwi	13	42	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	13	43	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	13	44	pore	pore	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	45	wall	wall	NN
work_icsipe3itza57oc7ahgvt4fxwi	13	46	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	14	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	2	cross	cross	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	3	-	-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	14	4	linked	link	VBN
work_icsipe3itza57oc7ahgvt4fxwi	14	5	VDAC1	vdac1	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	6	reconstituted	reconstitute	VBN
work_icsipe3itza57oc7ahgvt4fxwi	14	7	into	into	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	8	planar	planar	JJ
work_icsipe3itza57oc7ahgvt4fxwi	14	9	lipid	lipid	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	10	membranes	membrane	NNS
work_icsipe3itza57oc7ahgvt4fxwi	14	11	exhibited	exhibit	VBD
work_icsipe3itza57oc7ahgvt4fxwi	14	12	typical	typical	JJ
work_icsipe3itza57oc7ahgvt4fxwi	14	13	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	14	gating	gating	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	15	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	14	16	which	which	WDT
work_icsipe3itza57oc7ahgvt4fxwi	14	17	suggests	suggest	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	14	18	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	19	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	20	N	n	CD
work_icsipe3itza57oc7ahgvt4fxwi	14	21	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	14	22	terminal	terminal	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	23	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	24	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	14	25	helix	helix	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	26	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	14	27	located	locate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	14	28	inside	inside	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	29	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	30	pore	pore	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	31	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	32	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	14	33	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	34	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	35	open	open	JJ
work_icsipe3itza57oc7ahgvt4fxwi	14	36	state	state	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	37	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	14	38	remains	remain	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	14	39	associated	associate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	14	40	with	with	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	41	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	14	42	pore	pore	NNP
work_icsipe3itza57oc7ahgvt4fxwi	14	43	wall	wall	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	44	during	during	IN
work_icsipe3itza57oc7ahgvt4fxwi	14	45	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	46	gating	gating	NN
work_icsipe3itza57oc7ahgvt4fxwi	14	47	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	15	1	Our	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	15	2	findings	finding	NNS
work_icsipe3itza57oc7ahgvt4fxwi	15	3	support	support	VBP
work_icsipe3itza57oc7ahgvt4fxwi	15	4	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	15	5	model	model	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	6	where	where	WRB
work_icsipe3itza57oc7ahgvt4fxwi	15	7	b	b	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	8	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	15	9	bar-	bar-	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	10	rel	rel	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	11	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	15	12	not	not	RB
work_icsipe3itza57oc7ahgvt4fxwi	15	13	rigid	rigid	JJ
work_icsipe3itza57oc7ahgvt4fxwi	15	14	but	but	CC
work_icsipe3itza57oc7ahgvt4fxwi	15	15	undergoes	undergo	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	15	16	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	15	17	conformational	conformational	JJ
work_icsipe3itza57oc7ahgvt4fxwi	15	18	change	change	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	19	that	that	WDT
work_icsipe3itza57oc7ahgvt4fxwi	15	20	leads	lead	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	15	21	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	15	22	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	15	23	partial	partial	JJ
work_icsipe3itza57oc7ahgvt4fxwi	15	24	constriction	constriction	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	25	upon	upon	IN
work_icsipe3itza57oc7ahgvt4fxwi	15	26	transition	transition	NN
work_icsipe3itza57oc7ahgvt4fxwi	15	27	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	15	28	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	15	29	closed	close	VBN
work_icsipe3itza57oc7ahgvt4fxwi	15	30	states	state	NNS
work_icsipe3itza57oc7ahgvt4fxwi	15	31	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	16	1	3364-Pos	3364-Pos	NFP
work_icsipe3itza57oc7ahgvt4fxwi	16	2	Board	board	NN
work_icsipe3itza57oc7ahgvt4fxwi	16	3	B519	B519	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	4	Novel	Novel	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	5	Mechanism	Mechanism	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	6	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	16	7	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	8	Respiration	Respiration	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	9	Control	Control	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	10	through	through	IN
work_icsipe3itza57oc7ahgvt4fxwi	16	11	Competition	Competition	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	12	between	between	IN
work_icsipe3itza57oc7ahgvt4fxwi	16	13	Hexokinase-2	Hexokinase-2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	14	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	16	15	Tubulin	Tubulin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	16	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	16	17	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	18	Binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	16	19	Kely	Kely	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	20	L.	L.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	21	Sheldon1	Sheldon1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	22	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	16	23	Coert	Coert	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	24	J.	J.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	25	Zuurbier2	Zuurbier2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	26	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	16	27	Sergey	Sergey	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	28	M.	M.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	29	Bezrukov1	Bezrukov1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	30	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	16	31	Tatiana	Tatiana	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	32	K.	K.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	33	Rostovtseva1	Rostovtseva1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	16	34	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	17	1	1The	1the	CD
work_icsipe3itza57oc7ahgvt4fxwi	17	2	Natl	Natl	NNP
work_icsipe3itza57oc7ahgvt4fxwi	17	3	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	18	1	Institutes	Institutes	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	2	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	18	3	Health	Health	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	4	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	5	Bethesda	Bethesda	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	6	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	7	MD	MD	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	8	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	9	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	10	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	11	2University	2University	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	12	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	18	13	Amsterdam	Amsterdam	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	14	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	15	Amsterdam	Amsterdam	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	16	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	18	17	Netherlands	Netherlands	NNP
work_icsipe3itza57oc7ahgvt4fxwi	18	18	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	19	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	19	2	voltage	voltage	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	3	dependent	dependent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	19	4	anion	anion	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	5	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	6	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	19	7	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	19	8	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	19	9	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	19	10	involved	involve	VBN
work_icsipe3itza57oc7ahgvt4fxwi	19	11	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	19	12	regulation	regulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	13	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	19	14	me-	me-	CD
work_icsipe3itza57oc7ahgvt4fxwi	19	15	tabolite	tabolite	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	16	flux	flux	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	17	across	across	IN
work_icsipe3itza57oc7ahgvt4fxwi	19	18	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	19	19	mitochondrial	mitochondrial	JJ
work_icsipe3itza57oc7ahgvt4fxwi	19	20	outer	outer	JJ
work_icsipe3itza57oc7ahgvt4fxwi	19	21	membrane	membrane	NN
work_icsipe3itza57oc7ahgvt4fxwi	19	22	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	19	23	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	19	24	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	19	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	20	1	Hexokinse	Hexokinse	NNP
work_icsipe3itza57oc7ahgvt4fxwi	20	2	II	II	NNP
work_icsipe3itza57oc7ahgvt4fxwi	20	3	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	20	4	HK2	HK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	20	5	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	20	6	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	20	7	known	know	VBN
work_icsipe3itza57oc7ahgvt4fxwi	20	8	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	20	9	bind	bind	VB
work_icsipe3itza57oc7ahgvt4fxwi	20	10	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	20	11	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	20	12	where	where	WRB
work_icsipe3itza57oc7ahgvt4fxwi	20	13	it	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	20	14	phosphorylates	phosphorylate	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	20	15	glucose	glucose	NN
work_icsipe3itza57oc7ahgvt4fxwi	20	16	into	into	IN
work_icsipe3itza57oc7ahgvt4fxwi	20	17	glucose-6-phosphate	glucose-6-phosphate	NNP
work_icsipe3itza57oc7ahgvt4fxwi	20	18	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	20	19	G6P	g6p	NN
work_icsipe3itza57oc7ahgvt4fxwi	20	20	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	20	21	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	21	1	High	high	JJ
work_icsipe3itza57oc7ahgvt4fxwi	21	2	expression	expression	NN
work_icsipe3itza57oc7ahgvt4fxwi	21	3	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	21	4	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	21	5	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	21	6	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	21	7	common	common	JJ
work_icsipe3itza57oc7ahgvt4fxwi	21	8	phenotype	phenotype	NN
work_icsipe3itza57oc7ahgvt4fxwi	21	9	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	21	10	many	many	JJ
work_icsipe3itza57oc7ahgvt4fxwi	21	11	cancers	cancer	NNS
work_icsipe3itza57oc7ahgvt4fxwi	21	12	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	21	13	where	where	WRB
work_icsipe3itza57oc7ahgvt4fxwi	21	14	its	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	21	15	concentration	concentration	NN
work_icsipe3itza57oc7ahgvt4fxwi	21	16	can	can	MD
work_icsipe3itza57oc7ahgvt4fxwi	21	17	be	be	VB
work_icsipe3itza57oc7ahgvt4fxwi	21	18	200	200	CD
work_icsipe3itza57oc7ahgvt4fxwi	21	19	times	time	NNS
work_icsipe3itza57oc7ahgvt4fxwi	21	20	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	21	21	that	that	DT
work_icsipe3itza57oc7ahgvt4fxwi	21	22	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	21	23	noncan-	noncan-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	21	24	cerous	cerous	JJ
work_icsipe3itza57oc7ahgvt4fxwi	21	25	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	21	26	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	21	27	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	21	28	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	21	29	implicated	implicate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	21	30	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	21	31	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	21	32	Warburg	Warburg	NNP
work_icsipe3itza57oc7ahgvt4fxwi	21	33	effect	effect	NN
work_icsipe3itza57oc7ahgvt4fxwi	21	34	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	22	1	It	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	22	2	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	22	3	believed	believe	VBN
work_icsipe3itza57oc7ahgvt4fxwi	22	4	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	22	5	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	22	6	serves	serve	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	22	7	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	22	8	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	22	9	HXK2	hxk2	NN
work_icsipe3itza57oc7ahgvt4fxwi	22	10	binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	22	11	site	site	NN
work_icsipe3itza57oc7ahgvt4fxwi	22	12	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	22	13	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	22	14	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	22	15	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	23	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	23	2	15	15	CD
work_icsipe3itza57oc7ahgvt4fxwi	23	3	amino	amino	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	4	acid	acid	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	5	N	N	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	6	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	23	7	ter-	ter-	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	8	minal	minal	JJ
work_icsipe3itza57oc7ahgvt4fxwi	23	9	sequence	sequence	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	10	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	11	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	12	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	23	13	responsible	responsible	JJ
work_icsipe3itza57oc7ahgvt4fxwi	23	14	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	15	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	16	binding	binding	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	17	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	23	18	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	23	19	when	when	WRB
work_icsipe3itza57oc7ahgvt4fxwi	23	20	conjugated	conjugate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	23	21	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	22	TAT	TAT	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	23	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	23	24	TAT	TAT	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	25	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	23	26	HK2	HK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	27	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	23	28	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	23	29	binds	bind	NNS
work_icsipe3itza57oc7ahgvt4fxwi	23	30	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	31	mitochondria	mitochondria	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	32	with	with	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	33	higher	high	JJR
work_icsipe3itza57oc7ahgvt4fxwi	23	34	affinity	affinity	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	35	than	than	IN
work_icsipe3itza57oc7ahgvt4fxwi	23	36	native	native	JJ
work_icsipe3itza57oc7ahgvt4fxwi	23	37	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	38	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	23	39	causing	cause	VBG
work_icsipe3itza57oc7ahgvt4fxwi	23	40	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	23	41	detachment	detachment	NN
work_icsipe3itza57oc7ahgvt4fxwi	23	42	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	24	1	We	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	24	2	have	have	VBP
work_icsipe3itza57oc7ahgvt4fxwi	24	3	previously	previously	RB
work_icsipe3itza57oc7ahgvt4fxwi	24	4	found	find	VBN
work_icsipe3itza57oc7ahgvt4fxwi	24	5	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	24	6	dimeric	dimeric	JJ
work_icsipe3itza57oc7ahgvt4fxwi	24	7	tubulin	tubulin	NN
work_icsipe3itza57oc7ahgvt4fxwi	24	8	reversibly	reversibly	RB
work_icsipe3itza57oc7ahgvt4fxwi	24	9	binds	bind	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	24	10	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	24	11	partially	partially	RB
work_icsipe3itza57oc7ahgvt4fxwi	24	12	blocks	block	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	24	13	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	24	14	inhibiting	inhibit	VBG
work_icsipe3itza57oc7ahgvt4fxwi	24	15	me-	me-	XX
work_icsipe3itza57oc7ahgvt4fxwi	24	16	tabolite	tabolite	NN
work_icsipe3itza57oc7ahgvt4fxwi	24	17	flux	flux	NN
work_icsipe3itza57oc7ahgvt4fxwi	24	18	across	across	IN
work_icsipe3itza57oc7ahgvt4fxwi	24	19	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	24	20	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	24	21	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	25	1	Now	now	RB
work_icsipe3itza57oc7ahgvt4fxwi	25	2	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	25	3	show	show	VBP
work_icsipe3itza57oc7ahgvt4fxwi	25	4	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	25	5	this	this	DT
work_icsipe3itza57oc7ahgvt4fxwi	25	6	binding	binding	NN
work_icsipe3itza57oc7ahgvt4fxwi	25	7	can	can	MD
work_icsipe3itza57oc7ahgvt4fxwi	25	8	be	be	VB
work_icsipe3itza57oc7ahgvt4fxwi	25	9	attenuated	attenuate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	25	10	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	25	11	TAT	TAT	NNP
work_icsipe3itza57oc7ahgvt4fxwi	25	12	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	25	13	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	25	14	peptide	peptide	NN
work_icsipe3itza57oc7ahgvt4fxwi	25	15	as	as	RB
work_icsipe3itza57oc7ahgvt4fxwi	25	16	well	well	RB
work_icsipe3itza57oc7ahgvt4fxwi	25	17	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	25	18	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	25	19	full	full	JJ
work_icsipe3itza57oc7ahgvt4fxwi	25	20	length	length	NN
work_icsipe3itza57oc7ahgvt4fxwi	25	21	HXK2	hxk2	CD
work_icsipe3itza57oc7ahgvt4fxwi	25	22	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	26	1	We	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	26	2	have	have	VBP
work_icsipe3itza57oc7ahgvt4fxwi	26	3	found	find	VBN
work_icsipe3itza57oc7ahgvt4fxwi	26	4	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	26	5	TAT	TAT	NNP
work_icsipe3itza57oc7ahgvt4fxwi	26	6	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	26	7	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	26	8	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	26	9	recombinant	recombinant	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	10	full	full	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	11	length	length	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	12	HXK2	HXK2	NNS
work_icsipe3itza57oc7ahgvt4fxwi	26	13	inhibit	inhibit	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	14	tubulin	tubulin	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	15	blockage	blockage	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	16	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	26	17	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	26	18	reconstituted	reconstitute	VBN
work_icsipe3itza57oc7ahgvt4fxwi	26	19	into	into	IN
work_icsipe3itza57oc7ahgvt4fxwi	26	20	planar	planar	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	21	lipid	lipid	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	22	bilayers	bilayer	NNS
work_icsipe3itza57oc7ahgvt4fxwi	26	23	without	without	IN
work_icsipe3itza57oc7ahgvt4fxwi	26	24	altering	alter	VBG
work_icsipe3itza57oc7ahgvt4fxwi	26	25	characteristic	characteristic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	26	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	27	properties	property	NNS
work_icsipe3itza57oc7ahgvt4fxwi	26	28	such	such	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	29	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	26	30	single	single	JJ
work_icsipe3itza57oc7ahgvt4fxwi	26	31	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	32	conductance	conductance	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	33	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	26	34	selectivity	selectivity	NN
work_icsipe3itza57oc7ahgvt4fxwi	26	35	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	27	1	Binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	27	2	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	27	3	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	27	4	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	27	5	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	27	6	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	27	7	verified	verify	VBN
work_icsipe3itza57oc7ahgvt4fxwi	27	8	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	27	9	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	27	10	generation	generation	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	11	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	27	12	high	high	JJ
work_icsipe3itza57oc7ahgvt4fxwi	27	13	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	27	14	frequency	frequency	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	15	excess	excess	JJ
work_icsipe3itza57oc7ahgvt4fxwi	27	16	cur-	cur-	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	17	rent	rent	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	18	noise	noise	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	19	without	without	IN
work_icsipe3itza57oc7ahgvt4fxwi	27	20	channel	channel	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	21	closure	closure	NN
work_icsipe3itza57oc7ahgvt4fxwi	27	22	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	28	1	HXK2	hxk2	CD
work_icsipe3itza57oc7ahgvt4fxwi	28	2	bound	bind	VBN
work_icsipe3itza57oc7ahgvt4fxwi	28	3	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	28	4	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	28	5	prevents	prevent	NNS
work_icsipe3itza57oc7ahgvt4fxwi	28	6	subse-	subse-	VBP
work_icsipe3itza57oc7ahgvt4fxwi	28	7	quent	quent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	28	8	tubulin	tubulin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	28	9	binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	28	10	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	28	11	but	but	CC
work_icsipe3itza57oc7ahgvt4fxwi	28	12	only	only	RB
work_icsipe3itza57oc7ahgvt4fxwi	28	13	when	when	WRB
work_icsipe3itza57oc7ahgvt4fxwi	28	14	added	add	VBN
work_icsipe3itza57oc7ahgvt4fxwi	28	15	before	before	IN
work_icsipe3itza57oc7ahgvt4fxwi	28	16	tubulin	tubulin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	28	17	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	28	18	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	28	19	inhibits	inhibit	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	28	20	tubulin	tubulin	NN
work_icsipe3itza57oc7ahgvt4fxwi	28	21	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	28	22	induced	induce	VBN
work_icsipe3itza57oc7ahgvt4fxwi	28	23	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	28	24	blockage	blockage	NN
work_icsipe3itza57oc7ahgvt4fxwi	28	25	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	28	26	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	28	27	dose	dose	JJ
work_icsipe3itza57oc7ahgvt4fxwi	28	28	dependent	dependent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	28	29	manner	manner	NN
work_icsipe3itza57oc7ahgvt4fxwi	28	30	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	29	1	Moreover	moreover	RB
work_icsipe3itza57oc7ahgvt4fxwi	29	2	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	29	3	G6P	g6p	CD
work_icsipe3itza57oc7ahgvt4fxwi	29	4	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	29	5	which	which	WDT
work_icsipe3itza57oc7ahgvt4fxwi	29	6	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	29	7	known	know	VBN
work_icsipe3itza57oc7ahgvt4fxwi	29	8	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	29	9	cause	cause	VB
work_icsipe3itza57oc7ahgvt4fxwi	29	10	HXK2	hxk2	CD
work_icsipe3itza57oc7ahgvt4fxwi	29	11	detachment	detachment	NN
work_icsipe3itza57oc7ahgvt4fxwi	29	12	from	from	IN
work_icsipe3itza57oc7ahgvt4fxwi	29	13	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	29	14	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	29	15	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	29	16	fully	fully	RB
work_icsipe3itza57oc7ahgvt4fxwi	29	17	re-	re-	VBP
work_icsipe3itza57oc7ahgvt4fxwi	29	18	verses	verses	IN
work_icsipe3itza57oc7ahgvt4fxwi	29	19	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	29	20	inhibition	inhibition	NN
work_icsipe3itza57oc7ahgvt4fxwi	29	21	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	29	22	tubulin	tubulin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	29	23	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	29	24	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	29	25	binding	binding	JJ
work_icsipe3itza57oc7ahgvt4fxwi	29	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	30	1	This	this	DT
work_icsipe3itza57oc7ahgvt4fxwi	30	2	suggests	suggest	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	30	3	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	30	4	HXK2	hxk2	PRP
work_icsipe3itza57oc7ahgvt4fxwi	30	5	de-	de-	RB
work_icsipe3itza57oc7ahgvt4fxwi	30	6	tachment	tachment	NN
work_icsipe3itza57oc7ahgvt4fxwi	30	7	from	from	IN
work_icsipe3itza57oc7ahgvt4fxwi	30	8	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	30	9	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	30	10	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	30	11	hence	hence	RB
work_icsipe3itza57oc7ahgvt4fxwi	30	12	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	30	13	MOM	MOM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	30	14	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	30	15	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	30	16	caused	cause	VBN
work_icsipe3itza57oc7ahgvt4fxwi	30	17	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	30	18	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	30	19	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	30	20	conformational	conformational	JJ
work_icsipe3itza57oc7ahgvt4fxwi	30	21	change	change	NN
work_icsipe3itza57oc7ahgvt4fxwi	30	22	upon	upon	IN
work_icsipe3itza57oc7ahgvt4fxwi	30	23	G6P	g6p	JJ
work_icsipe3itza57oc7ahgvt4fxwi	30	24	binding	binding	NN
work_icsipe3itza57oc7ahgvt4fxwi	30	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	31	1	Thus	thus	RB
work_icsipe3itza57oc7ahgvt4fxwi	31	2	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	31	3	propose	propose	VBP
work_icsipe3itza57oc7ahgvt4fxwi	31	4	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	31	5	novel	novel	JJ
work_icsipe3itza57oc7ahgvt4fxwi	31	6	mecha-	mecha-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	31	7	nism	nism	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	8	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	31	9	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	10	respiration	respiration	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	11	control	control	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	12	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	31	13	cancer	cancer	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	14	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	31	15	through	through	IN
work_icsipe3itza57oc7ahgvt4fxwi	31	16	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	31	17	competi-	competi-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	31	18	tion	tion	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	19	between	between	IN
work_icsipe3itza57oc7ahgvt4fxwi	31	20	HXK2	HXK2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	31	21	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	31	22	tubulin	tubulin	NN
work_icsipe3itza57oc7ahgvt4fxwi	31	23	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	31	24	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	31	25	binding	binding	JJ
work_icsipe3itza57oc7ahgvt4fxwi	31	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	32	1	3365-Pos	3365-Pos	NFP
work_icsipe3itza57oc7ahgvt4fxwi	32	2	Board	board	NN
work_icsipe3itza57oc7ahgvt4fxwi	32	3	B520	B520	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	4	Reprogramming	Reprogramming	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	32	6	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	7	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	8	2D	2d	VB
work_icsipe3itza57oc7ahgvt4fxwi	32	9	Handling	handle	VBG
work_icsipe3itza57oc7ahgvt4fxwi	32	10	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	32	11	MICU1-Deficient	MICU1-Deficient	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	12	HeLa	HeLa	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	13	Cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	32	14	Tünde	Tünde	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	15	Golenár1	golenár1	NN
work_icsipe3itza57oc7ahgvt4fxwi	32	16	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	17	György	György	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	18	Csordás1	csordás1	ADD
work_icsipe3itza57oc7ahgvt4fxwi	32	19	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	20	Erin	Erin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	21	L.	L.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	22	Seifert1	Seifert1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	23	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	24	Cynthia	Cynthia	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	25	Moffat1	Moffat1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	26	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	27	Fabiana	Fabiana	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	28	Perocchi2	Perocchi2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	29	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	30	Yasemin	Yasemin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	31	Sancak2	Sancak2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	32	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	33	David	David	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	34	Weaver1	Weaver1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	35	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	36	Vamsi	Vamsi	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	37	K.	K.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	38	Mootha2	Mootha2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	39	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	32	40	György	György	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	41	Hajnóczky1	Hajnóczky1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	32	42	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	33	1	1	1	CD
work_icsipe3itza57oc7ahgvt4fxwi	33	2	Thomas	Thomas	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	3	Jefferson	Jefferson	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	4	University	University	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	5	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	6	Philadelphia	Philadelphia	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	7	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	8	PA	PA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	9	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	10	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	11	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	12	2	2	CD
work_icsipe3itza57oc7ahgvt4fxwi	33	13	Harvard	Harvard	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	14	Medical	Medical	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	15	School	School	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	16	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	33	17	Massachusetts	Massachusetts	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	18	General	General	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	19	Hospital	Hospital	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	20	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	21	Boston	Boston	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	22	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	23	MA	MA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	24	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	33	25	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	33	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	34	1	Recent	recent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	34	2	studies	study	NNS
work_icsipe3itza57oc7ahgvt4fxwi	34	3	have	have	VBP
work_icsipe3itza57oc7ahgvt4fxwi	34	4	revealed	reveal	VBN
work_icsipe3itza57oc7ahgvt4fxwi	34	5	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	34	6	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	34	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	34	8	pore	pore	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	9	forming	form	VBG
work_icsipe3itza57oc7ahgvt4fxwi	34	10	domain	domain	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	11	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	34	12	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	13	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	34	14	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	34	15	critical	critical	JJ
work_icsipe3itza57oc7ahgvt4fxwi	34	16	Ca2þ	ca2þ	JJ
work_icsipe3itza57oc7ahgvt4fxwi	34	17	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	34	18	sensitive	sensitive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	34	19	regulator	regulator	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	20	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	34	21	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	34	22	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	23	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	24	uniporter	uniporter	NN
work_icsipe3itza57oc7ahgvt4fxwi	34	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	35	1	How-	How-	NNP
work_icsipe3itza57oc7ahgvt4fxwi	35	2	ever	ever	RB
work_icsipe3itza57oc7ahgvt4fxwi	35	3	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	35	4	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	35	5	exact	exact	JJ
work_icsipe3itza57oc7ahgvt4fxwi	35	6	role	role	NN
work_icsipe3itza57oc7ahgvt4fxwi	35	7	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	35	8	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	35	9	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	35	10	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	35	11	transport	transport	NN
work_icsipe3itza57oc7ahgvt4fxwi	35	12	remains	remain	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	35	13	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	35	14	be	be	VB
work_icsipe3itza57oc7ahgvt4fxwi	35	15	addressed	address	VBN
work_icsipe3itza57oc7ahgvt4fxwi	35	16	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	36	1	Our	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	36	2	previous	previous	JJ
work_icsipe3itza57oc7ahgvt4fxwi	36	3	studies	study	NNS
work_icsipe3itza57oc7ahgvt4fxwi	36	4	showed	show	VBD
work_icsipe3itza57oc7ahgvt4fxwi	36	5	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	36	6	prolonged	prolong	VBD
work_icsipe3itza57oc7ahgvt4fxwi	36	7	down	down	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	8	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	36	9	regulation	regulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	10	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	36	11	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	12	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	36	13	HeLa	HeLa	NNP
work_icsipe3itza57oc7ahgvt4fxwi	36	14	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	36	15	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	16	shMICU1	shmicu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	17	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	18	promotes	promote	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	36	19	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	20	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	36	21	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	36	22	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	23	at	at	IN
work_icsipe3itza57oc7ahgvt4fxwi	36	24	low	low	JJ
work_icsipe3itza57oc7ahgvt4fxwi	36	25	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	26	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	36	27	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	36	28	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	29	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	36	30	which	which	WDT
work_icsipe3itza57oc7ahgvt4fxwi	36	31	unexpectedly	unexpectedly	RB
work_icsipe3itza57oc7ahgvt4fxwi	36	32	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	36	33	fails	fail	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	36	34	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	36	35	effectively	effectively	RB
work_icsipe3itza57oc7ahgvt4fxwi	36	36	increase	increase	VB
work_icsipe3itza57oc7ahgvt4fxwi	36	37	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	36	38	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	39	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	36	40	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	36	41	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	36	42	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	37	1	To	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	37	2	determine	determine	VB
work_icsipe3itza57oc7ahgvt4fxwi	37	3	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	37	4	source	source	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	37	6	discrepancy	discrepancy	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	7	between	between	IN
work_icsipe3itza57oc7ahgvt4fxwi	37	8	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	37	9	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	10	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	37	11	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	37	12	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	13	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	37	14	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	37	15	ma-	ma-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	37	16	trix	trix	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	17	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	37	18	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	19	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	37	20	phenotypes	phenotype	NNS
work_icsipe3itza57oc7ahgvt4fxwi	37	21	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	37	22	first	first	RB
work_icsipe3itza57oc7ahgvt4fxwi	37	23	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	37	24	simultaneously	simultaneously	RB
work_icsipe3itza57oc7ahgvt4fxwi	37	25	monitored	monitor	VBD
work_icsipe3itza57oc7ahgvt4fxwi	37	26	ruthenium	ruthenium	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	27	red-	red-	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	28	sensitive	sensitive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	37	29	clearance	clearance	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	30	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	37	31	added	add	VBN
work_icsipe3itza57oc7ahgvt4fxwi	37	32	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	33	from	from	IN
work_icsipe3itza57oc7ahgvt4fxwi	37	34	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	37	35	cytoplasm	cytoplasm	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	36	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	37	37	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	37	38	corresponding	corresponding	JJ
work_icsipe3itza57oc7ahgvt4fxwi	37	39	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	40	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	37	41	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	42	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	37	43	response	response	NN
work_icsipe3itza57oc7ahgvt4fxwi	37	44	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	37	45	permeabilized	permeabilized	JJ
work_icsipe3itza57oc7ahgvt4fxwi	37	46	shMICU1	shmicu1	CD
work_icsipe3itza57oc7ahgvt4fxwi	37	47	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	37	48	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	38	1	Under	under	IN
work_icsipe3itza57oc7ahgvt4fxwi	38	2	conditions	condition	NNS
work_icsipe3itza57oc7ahgvt4fxwi	38	3	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	38	4	similar	similar	JJ
work_icsipe3itza57oc7ahgvt4fxwi	38	5	cytoplasmic	cytoplasmic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	38	6	Ca	ca	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	7	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	38	8	clearance	clearance	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	9	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	38	10	shMICU1	shmicu1	CD
work_icsipe3itza57oc7ahgvt4fxwi	38	11	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	38	12	showed	show	VBD
work_icsipe3itza57oc7ahgvt4fxwi	38	13	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	38	14	smaller	small	JJR
work_icsipe3itza57oc7ahgvt4fxwi	38	15	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	16	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	38	17	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	38	18	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	38	19	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	38	20	increase	increase	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	21	than	than	IN
work_icsipe3itza57oc7ahgvt4fxwi	38	22	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	38	23	control	control	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	24	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	38	25	indicating	indicate	VBG
work_icsipe3itza57oc7ahgvt4fxwi	38	26	enhanced	enhance	VBN
work_icsipe3itza57oc7ahgvt4fxwi	38	27	buffering	buffering	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	28	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	38	29	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	38	30	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	38	31	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	38	32	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	38	33	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	38	34	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	39	1	Enhanced	Enhanced	NNP
work_icsipe3itza57oc7ahgvt4fxwi	39	2	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	39	3	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	39	4	binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	39	5	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	39	6	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	39	7	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	39	8	likely	likely	RB
work_icsipe3itza57oc7ahgvt4fxwi	39	9	reflects	reflect	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	39	10	alkalinization	alkalinization	NN
work_icsipe3itza57oc7ahgvt4fxwi	39	11	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	39	12	enhanced	enhanced	JJ
work_icsipe3itza57oc7ahgvt4fxwi	39	13	phosphate	phosphate	NN
work_icsipe3itza57oc7ahgvt4fxwi	39	14	transport	transport	NN
work_icsipe3itza57oc7ahgvt4fxwi	39	15	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	40	1	To	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	40	2	test	test	VB
work_icsipe3itza57oc7ahgvt4fxwi	40	3	if	if	IN
work_icsipe3itza57oc7ahgvt4fxwi	40	4	upregulation	upregulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	40	6	Ca2þ	Ca2þ	NNP
work_icsipe3itza57oc7ahgvt4fxwi	40	7	buffering	buffering	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	8	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	40	9	di-	di-	RB
work_icsipe3itza57oc7ahgvt4fxwi	40	10	rectly	rectly	RB
work_icsipe3itza57oc7ahgvt4fxwi	40	11	linked	link	VBN
work_icsipe3itza57oc7ahgvt4fxwi	40	12	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	40	13	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	14	depletion	depletion	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	15	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	40	16	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	40	17	also	also	RB
work_icsipe3itza57oc7ahgvt4fxwi	40	18	assessed	assess	VBD
work_icsipe3itza57oc7ahgvt4fxwi	40	19	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	20	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	21	han-	han-	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	22	dling	dle	VBG
work_icsipe3itza57oc7ahgvt4fxwi	40	23	after	after	IN
work_icsipe3itza57oc7ahgvt4fxwi	40	24	72hr	72hr	JJ
work_icsipe3itza57oc7ahgvt4fxwi	40	25	silencing	silencing	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	26	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	40	27	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	40	28	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	40	29	siMICU1	siMICU1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	40	30	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	40	31	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	41	1	In	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	41	2	siMICU1cells	siMICU1cells	NNP
work_icsipe3itza57oc7ahgvt4fxwi	41	3	both	both	DT
work_icsipe3itza57oc7ahgvt4fxwi	41	4	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	5	Ca	ca	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	6	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	41	7	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	8	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	41	9	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	41	10	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	11	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	41	12	Ca	ca	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	13	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	41	14	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	41	15	rise	rise	NN
work_icsipe3itza57oc7ahgvt4fxwi	41	16	were	be	VBD
work_icsipe3itza57oc7ahgvt4fxwi	41	17	effectively	effectively	RB
work_icsipe3itza57oc7ahgvt4fxwi	41	18	stimu-	stimu-	VBN
work_icsipe3itza57oc7ahgvt4fxwi	41	19	lated	late	VBN
work_icsipe3itza57oc7ahgvt4fxwi	41	20	at	at	IN
work_icsipe3itza57oc7ahgvt4fxwi	41	21	low	low	JJ
work_icsipe3itza57oc7ahgvt4fxwi	41	22	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	41	23	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	41	24	levels	level	NNS
work_icsipe3itza57oc7ahgvt4fxwi	41	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	42	1	Thus	thus	RB
work_icsipe3itza57oc7ahgvt4fxwi	42	2	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	42	3	upregulation	upregulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	4	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	42	5	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	6	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	42	7	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	42	8	buffering	buffering	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	9	seems	seem	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	42	10	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	42	11	be	be	VB
work_icsipe3itza57oc7ahgvt4fxwi	42	12	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	42	13	component	component	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	14	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	42	15	an	an	DT
work_icsipe3itza57oc7ahgvt4fxwi	42	16	adaptive	adaptive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	42	17	response	response	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	18	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	42	19	sensitization	sensitization	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	20	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	42	21	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	22	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	42	23	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	42	24	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	42	25	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	42	26	shMICU1	shMICU1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	42	27	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	43	1	The	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	43	2	adaptive	adaptive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	43	3	response	response	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	4	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	43	5	likely	likely	JJ
work_icsipe3itza57oc7ahgvt4fxwi	43	6	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	43	7	be	be	VB
work_icsipe3itza57oc7ahgvt4fxwi	43	8	important	important	JJ
work_icsipe3itza57oc7ahgvt4fxwi	43	9	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	43	10	attenuate	attenuate	VB
work_icsipe3itza57oc7ahgvt4fxwi	43	11	some	some	DT
work_icsipe3itza57oc7ahgvt4fxwi	43	12	MICU1-depletion	MICU1-depletion	NNP
work_icsipe3itza57oc7ahgvt4fxwi	43	13	induced	induce	VBD
work_icsipe3itza57oc7ahgvt4fxwi	43	14	cellular	cellular	JJ
work_icsipe3itza57oc7ahgvt4fxwi	43	15	impairments	impairment	NNS
work_icsipe3itza57oc7ahgvt4fxwi	43	16	that	that	WDT
work_icsipe3itza57oc7ahgvt4fxwi	43	17	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	43	18	found	find	VBD
work_icsipe3itza57oc7ahgvt4fxwi	43	19	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	43	20	manifest	manifest	VB
work_icsipe3itza57oc7ahgvt4fxwi	43	21	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	43	22	attenuated	attenuate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	43	23	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	24	ATP	atp	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	25	production	production	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	26	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	43	27	cell	cell	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	28	proliferation	proliferation	NN
work_icsipe3itza57oc7ahgvt4fxwi	43	29	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	44	1	3366-Pos	3366-Pos	NFP
work_icsipe3itza57oc7ahgvt4fxwi	44	2	Board	board	NN
work_icsipe3itza57oc7ahgvt4fxwi	44	3	B521	B521	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	4	MICU1-dependent	MICU1-dependent	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	5	Threshold	Threshold	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	6	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	44	7	Cooperativity	Cooperativity	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	8	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	44	9	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	10	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	11	2D	2D	VBD
work_icsipe3itza57oc7ahgvt4fxwi	44	12	Uptake	Uptake	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	13	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	44	14	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	44	15	Liver	Liver	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	16	György	György	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	17	Csordás1	csordás1	ADD
work_icsipe3itza57oc7ahgvt4fxwi	44	18	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	19	Erin	Erin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	20	L.	L.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	21	Seifert1	Seifert1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	22	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	23	Tünde	Tünde	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	24	Golenár1	golenár1	NN
work_icsipe3itza57oc7ahgvt4fxwi	44	25	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	26	Cynthia	Cynthia	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	27	Moffat1	Moffat1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	28	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	29	Sergio	Sergio	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	30	de	de	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	31	la	la	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	32	Fuente	Fuente	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	33	Perez1	Perez1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	34	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	35	David	David	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	36	Weaver1	Weaver1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	37	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	38	Roman	Roman	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	39	Bogorad2	Bogorad2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	40	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	41	Victor	Victor	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	42	Koteliansky2	Koteliansky2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	43	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	44	Vamsi	Vamsi	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	45	K.	K.	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	46	Mootha3	Mootha3	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	47	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	44	48	György	György	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	49	Hajnóczky1	Hajnóczky1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	44	50	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	45	1	1Thomas	1Thomas	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	2	Jefferson	Jefferson	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	3	University	University	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	4	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	5	Philadelphia	Philadelphia	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	6	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	7	PA	PA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	8	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	9	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	10	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	11	2Koch	2Koch	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	12	Institute	Institute	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	13	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	45	14	Integrative	Integrative	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	15	Cancer	Cancer	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	16	Research	Research	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	17	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	18	MIT	MIT	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	19	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	20	Cambridge	Cambridge	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	21	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	22	MA	MA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	23	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	24	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	25	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	26	3	3	CD
work_icsipe3itza57oc7ahgvt4fxwi	45	27	Harvard	Harvard	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	28	Medical	Medical	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	29	School	School	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	30	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	45	31	Massachusetts	Massachusetts	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	32	General	General	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	33	Hospital	Hospital	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	34	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	35	Boston	Boston	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	36	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	37	MA	MA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	38	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	45	39	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	45	40	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	46	1	Recent	recent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	46	2	studies	study	NNS
work_icsipe3itza57oc7ahgvt4fxwi	46	3	have	have	VBP
work_icsipe3itza57oc7ahgvt4fxwi	46	4	revealed	reveal	VBN
work_icsipe3itza57oc7ahgvt4fxwi	46	5	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	46	6	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	46	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	46	8	pore	pore	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	9	forming	form	VBG
work_icsipe3itza57oc7ahgvt4fxwi	46	10	domain	domain	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	11	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	46	12	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	13	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	46	14	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	46	15	critical	critical	JJ
work_icsipe3itza57oc7ahgvt4fxwi	46	16	Ca2þ	ca2þ	JJ
work_icsipe3itza57oc7ahgvt4fxwi	46	17	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	46	18	sensitive	sensitive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	46	19	regulator	regulator	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	20	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	46	21	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	46	22	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	23	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	24	uniporter	uniporter	NN
work_icsipe3itza57oc7ahgvt4fxwi	46	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	47	1	How-	How-	NNP
work_icsipe3itza57oc7ahgvt4fxwi	47	2	ever	ever	RB
work_icsipe3itza57oc7ahgvt4fxwi	47	3	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	47	4	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	47	5	mechanism	mechanism	NN
work_icsipe3itza57oc7ahgvt4fxwi	47	6	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	47	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	47	8	complex	complex	JJ
work_icsipe3itza57oc7ahgvt4fxwi	47	9	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	47	10	dependence	dependence	NN
work_icsipe3itza57oc7ahgvt4fxwi	47	11	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	47	12	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	47	13	uniporter	uniporter	JJ
work_icsipe3itza57oc7ahgvt4fxwi	47	14	activity	activity	NN
work_icsipe3itza57oc7ahgvt4fxwi	47	15	remains	remain	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	47	16	elusive	elusive	JJ
work_icsipe3itza57oc7ahgvt4fxwi	47	17	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	48	1	Our	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	48	2	previous	previous	JJ
work_icsipe3itza57oc7ahgvt4fxwi	48	3	studies	study	NNS
work_icsipe3itza57oc7ahgvt4fxwi	48	4	showed	show	VBD
work_icsipe3itza57oc7ahgvt4fxwi	48	5	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	48	6	prolonged	prolong	VBD
work_icsipe3itza57oc7ahgvt4fxwi	48	7	down	down	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	8	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	48	9	regulation	regulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	10	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	48	11	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	12	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	48	13	HeLa	HeLa	NNP
work_icsipe3itza57oc7ahgvt4fxwi	48	14	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	48	15	causes	cause	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	48	16	lower	low	JJR
work_icsipe3itza57oc7ahgvt4fxwi	48	17	threshold	threshold	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	18	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	48	19	decreased	decrease	VBD
work_icsipe3itza57oc7ahgvt4fxwi	48	20	cooperativity	cooperativity	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	21	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	48	22	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	48	23	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	48	24	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	48	25	uptake	uptake	VB
work_icsipe3itza57oc7ahgvt4fxwi	48	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	49	1	To	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	49	2	study	study	VB
work_icsipe3itza57oc7ahgvt4fxwi	49	3	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	49	4	functional	functional	JJ
work_icsipe3itza57oc7ahgvt4fxwi	49	5	significance	significance	NN
work_icsipe3itza57oc7ahgvt4fxwi	49	6	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	7	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	49	8	effects	effect	NNS
work_icsipe3itza57oc7ahgvt4fxwi	49	9	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	10	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	49	11	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	49	12	used	use	VBD
work_icsipe3itza57oc7ahgvt4fxwi	49	13	hepatocytes	hepatocyte	NNS
work_icsipe3itza57oc7ahgvt4fxwi	49	14	harvested	harvest	VBN
work_icsipe3itza57oc7ahgvt4fxwi	49	15	from	from	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	16	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	49	17	liver	liver	NN
work_icsipe3itza57oc7ahgvt4fxwi	49	18	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	19	mice	mouse	NNS
work_icsipe3itza57oc7ahgvt4fxwi	49	20	exposed	expose	VBN
work_icsipe3itza57oc7ahgvt4fxwi	49	21	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	22	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	49	23	vivo	vivo	NNP
work_icsipe3itza57oc7ahgvt4fxwi	49	24	silencing	silencing	NNP
work_icsipe3itza57oc7ahgvt4fxwi	49	25	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	49	26	4	4	CD
work_icsipe3itza57oc7ahgvt4fxwi	49	27	weeks	week	NNS
work_icsipe3itza57oc7ahgvt4fxwi	49	28	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	49	29	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	50	1	Silencing	silencing	NN
work_icsipe3itza57oc7ahgvt4fxwi	50	2	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	50	3	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	50	4	or	or	CC
work_icsipe3itza57oc7ahgvt4fxwi	50	5	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	50	6	resulted	result	VBD
work_icsipe3itza57oc7ahgvt4fxwi	50	7	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	50	8	>	>	NNP
work_icsipe3itza57oc7ahgvt4fxwi	50	9	80	80	CD
work_icsipe3itza57oc7ahgvt4fxwi	50	10	%	%	NN
work_icsipe3itza57oc7ahgvt4fxwi	50	11	decrease	decrease	NN
work_icsipe3itza57oc7ahgvt4fxwi	50	12	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	50	13	their	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	50	14	respective	respective	JJ
work_icsipe3itza57oc7ahgvt4fxwi	50	15	mRNA	mrna	NN
work_icsipe3itza57oc7ahgvt4fxwi	50	16	levels	level	NNS
work_icsipe3itza57oc7ahgvt4fxwi	50	17	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	51	1	Silencing	silencing	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	2	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	51	3	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	4	caused	cause	VBD
work_icsipe3itza57oc7ahgvt4fxwi	51	5	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	51	6	left-	left-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	51	7	ward	ward	NNP
work_icsipe3itza57oc7ahgvt4fxwi	51	8	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	51	9	shifted	shift	VBN
work_icsipe3itza57oc7ahgvt4fxwi	51	10	dose	dose	VBD
work_icsipe3itza57oc7ahgvt4fxwi	51	11	response	response	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	12	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	51	13	decreased	decrease	VBD
work_icsipe3itza57oc7ahgvt4fxwi	51	14	cooperativity	cooperativity	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	15	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	51	16	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	17	Ca2þ	Ca2þ	NNP
work_icsipe3itza57oc7ahgvt4fxwi	51	18	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	51	19	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	51	20	both	both	CC
work_icsipe3itza57oc7ahgvt4fxwi	51	21	permeabilized	permeabilized	JJ
work_icsipe3itza57oc7ahgvt4fxwi	51	22	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	51	23	intact	intact	JJ
work_icsipe3itza57oc7ahgvt4fxwi	51	24	hepatocytes	hepatocyte	NNS
work_icsipe3itza57oc7ahgvt4fxwi	51	25	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	52	1	By	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	2	contrast	contrast	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	3	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	52	4	silenc-	silenc-	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	5	ing	ing	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	6	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	7	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	52	8	resulted	result	VBD
work_icsipe3itza57oc7ahgvt4fxwi	52	9	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	10	slower	slow	JJR
work_icsipe3itza57oc7ahgvt4fxwi	52	11	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	52	12	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	52	13	uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	14	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	15	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	52	16	entire	entire	JJ
work_icsipe3itza57oc7ahgvt4fxwi	52	17	range	range	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	18	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	19	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	52	20	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	52	21	concen-	concen-	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	22	trations	tration	NNS
work_icsipe3itza57oc7ahgvt4fxwi	52	23	without	without	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	24	change	change	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	25	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	52	26	threshold	threshold	NN
work_icsipe3itza57oc7ahgvt4fxwi	52	27	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	53	1	Mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	2	respiration	respiration	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	3	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	53	4	cellular	cellular	JJ
work_icsipe3itza57oc7ahgvt4fxwi	53	5	ATP	atp	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	6	content	content	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	7	were	be	VBD
work_icsipe3itza57oc7ahgvt4fxwi	53	8	unaffected	unaffected	JJ
work_icsipe3itza57oc7ahgvt4fxwi	53	9	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	53	10	media	medium	NNS
work_icsipe3itza57oc7ahgvt4fxwi	53	11	containing	contain	VBG
work_icsipe3itza57oc7ahgvt4fxwi	53	12	both	both	CC
work_icsipe3itza57oc7ahgvt4fxwi	53	13	glycolytic	glycolytic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	53	14	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	53	15	mito-	mito-	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	16	chondrial	chondrial	JJ
work_icsipe3itza57oc7ahgvt4fxwi	53	17	fuels	fuel	NNS
work_icsipe3itza57oc7ahgvt4fxwi	53	18	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	53	19	either	either	DT
work_icsipe3itza57oc7ahgvt4fxwi	53	20	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	21	or	or	CC
work_icsipe3itza57oc7ahgvt4fxwi	53	22	MCU	mcu	NN
work_icsipe3itza57oc7ahgvt4fxwi	53	23	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	53	24	deficient	deficient	JJ
work_icsipe3itza57oc7ahgvt4fxwi	53	25	hepatocytes	hepatocyte	NNS
work_icsipe3itza57oc7ahgvt4fxwi	53	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	54	1	However	however	RB
work_icsipe3itza57oc7ahgvt4fxwi	54	2	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	54	3	si-	si-	CD
work_icsipe3itza57oc7ahgvt4fxwi	54	4	lencing	lencing	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	5	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	54	6	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	7	caused	cause	VBD
work_icsipe3itza57oc7ahgvt4fxwi	54	8	an	an	DT
work_icsipe3itza57oc7ahgvt4fxwi	54	9	augmented	augment	VBN
work_icsipe3itza57oc7ahgvt4fxwi	54	10	loss	loss	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	11	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	54	12	ATP	atp	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	13	when	when	WRB
work_icsipe3itza57oc7ahgvt4fxwi	54	14	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	54	15	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	54	16	were	be	VBD
work_icsipe3itza57oc7ahgvt4fxwi	54	17	confined	confine	VBN
work_icsipe3itza57oc7ahgvt4fxwi	54	18	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	54	19	oxidative	oxidative	JJ
work_icsipe3itza57oc7ahgvt4fxwi	54	20	metabolism	metabolism	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	21	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	54	22	an	an	DT
work_icsipe3itza57oc7ahgvt4fxwi	54	23	enhanced	enhance	VBN
work_icsipe3itza57oc7ahgvt4fxwi	54	24	sensitivity	sensitivity	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	25	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	54	26	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	27	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	54	28	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	54	29	overload	overload	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	30	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	54	31	permeabilization	permeabilization	NN
work_icsipe3itza57oc7ahgvt4fxwi	54	32	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	55	1	During	during	IN
work_icsipe3itza57oc7ahgvt4fxwi	55	2	stimulation	stimulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	3	with	with	IN
work_icsipe3itza57oc7ahgvt4fxwi	55	4	vasopressin	vasopressin	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	5	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	55	6	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	55	7	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	55	8	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	55	9	mobilizing	mobilize	VBG
work_icsipe3itza57oc7ahgvt4fxwi	55	10	hormone	hormone	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	11	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	55	12	both	both	DT
work_icsipe3itza57oc7ahgvt4fxwi	55	13	MICU1	micu1	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	14	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	55	15	MCU	mcu	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	16	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	55	17	deficient	deficient	JJ
work_icsipe3itza57oc7ahgvt4fxwi	55	18	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	55	19	displayed	display	VBD
work_icsipe3itza57oc7ahgvt4fxwi	55	20	an	an	DT
work_icsipe3itza57oc7ahgvt4fxwi	55	21	attenuated	attenuate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	55	22	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	23	matrix	matrix	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	24	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	55	25	Ca	Ca	NNP
work_icsipe3itza57oc7ahgvt4fxwi	55	26	2þ	2þ	CD
work_icsipe3itza57oc7ahgvt4fxwi	55	27	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	55	28	increase	increase	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	29	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	55	30	stimulation	stimulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	31	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	55	32	respira-	respira-	NNP
work_icsipe3itza57oc7ahgvt4fxwi	55	33	tion	tion	NN
work_icsipe3itza57oc7ahgvt4fxwi	55	34	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	56	1	Collectively	collectively	RB
work_icsipe3itza57oc7ahgvt4fxwi	56	2	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	56	3	these	these	DT
work_icsipe3itza57oc7ahgvt4fxwi	56	4	results	result	NNS
work_icsipe3itza57oc7ahgvt4fxwi	56	5	show	show	VBP
work_icsipe3itza57oc7ahgvt4fxwi	56	6	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	56	7	keeping	keep	VBG
work_icsipe3itza57oc7ahgvt4fxwi	56	8	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	56	9	gate	gate	NN
work_icsipe3itza57oc7ahgvt4fxwi	56	10	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	56	11	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	56	12	closed	close	VBN
work_icsipe3itza57oc7ahgvt4fxwi	56	13	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	56	14	MICU1	MICU1	NNS
work_icsipe3itza57oc7ahgvt4fxwi	56	15	at	at	IN
work_icsipe3itza57oc7ahgvt4fxwi	56	16	low	low	JJ
work_icsipe3itza57oc7ahgvt4fxwi	56	17	[	[	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	56	18	Ca2þ	ca2þ	NN
work_icsipe3itza57oc7ahgvt4fxwi	56	19	]	]	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	56	20	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	56	21	required	require	VBN
work_icsipe3itza57oc7ahgvt4fxwi	56	22	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	56	23	maintain	maintain	VB
work_icsipe3itza57oc7ahgvt4fxwi	56	24	healthy	healthy	JJ
work_icsipe3itza57oc7ahgvt4fxwi	56	25	mitochondria	mitochondrion	NNS
work_icsipe3itza57oc7ahgvt4fxwi	56	26	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	56	27	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	56	28	MICU1-mediated	MICU1-mediated	NNP
work_icsipe3itza57oc7ahgvt4fxwi	56	29	control	control	NN
work_icsipe3itza57oc7ahgvt4fxwi	56	30	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	56	31	MCU	MCU	NNP
work_icsipe3itza57oc7ahgvt4fxwi	56	32	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	56	33	cooperativity	cooperativity	NN
work_icsipe3itza57oc7ahgvt4fxwi	56	34	?	?	.
work_icsipe3itza57oc7ahgvt4fxwi	56	35	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	57	1	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	57	2	required	require	VBN
work_icsipe3itza57oc7ahgvt4fxwi	57	3	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	57	4	support	support	VB
work_icsipe3itza57oc7ahgvt4fxwi	57	5	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	57	6	propagation	propagation	NN
work_icsipe3itza57oc7ahgvt4fxwi	57	7	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	57	8	short	short	RB
work_icsipe3itza57oc7ahgvt4fxwi	57	9	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	57	10	lasting	last	VBG
work_icsipe3itza57oc7ahgvt4fxwi	57	11	calcium	calcium	NN
work_icsipe3itza57oc7ahgvt4fxwi	57	12	spikes	spike	NNS
work_icsipe3itza57oc7ahgvt4fxwi	57	13	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	57	14	oscillations	oscillation	NNS
work_icsipe3itza57oc7ahgvt4fxwi	57	15	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	57	16	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	57	17	mitochondria	mitochondria	NN
work_icsipe3itza57oc7ahgvt4fxwi	57	18	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	57	19	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	57	20	ensuing	ensue	VBG
work_icsipe3itza57oc7ahgvt4fxwi	57	21	physiological	physiological	JJ
work_icsipe3itza57oc7ahgvt4fxwi	57	22	stimulation	stimulation	NN
work_icsipe3itza57oc7ahgvt4fxwi	57	23	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	57	24	oxidative	oxidative	JJ
work_icsipe3itza57oc7ahgvt4fxwi	57	25	metabolism	metabolism	NN
work_icsipe3itza57oc7ahgvt4fxwi	57	26	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	58	1	3367-Pos	3367-Pos	NFP
work_icsipe3itza57oc7ahgvt4fxwi	58	2	Board	board	NN
work_icsipe3itza57oc7ahgvt4fxwi	58	3	B522	B522	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	4	Targeting	Targeting	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	5	Mcl-1	Mcl-1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	6	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	58	7	Bak	Bak	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	8	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	58	9	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	58	10	Therapeutic	therapeutic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	58	11	Tool	tool	NN
work_icsipe3itza57oc7ahgvt4fxwi	58	12	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	58	13	Selectively	selectively	RB
work_icsipe3itza57oc7ahgvt4fxwi	58	14	Induce	induce	VB
work_icsipe3itza57oc7ahgvt4fxwi	58	15	Apoptosis	Apoptosis	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	16	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	58	17	Hepaptocellualr	Hepaptocellualr	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	18	Carcinoma	Carcinoma	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	19	Nima	Nima	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	20	Niknejad	Niknejad	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	21	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	58	22	Soumya	Soumya	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	23	Sinha	Sinha	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	24	Roy	Roy	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	25	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	58	26	Eric	Eric	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	27	Knudsen	Knudsen	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	28	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	58	29	György	György	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	30	Hajnóczky	Hajnóczky	NNP
work_icsipe3itza57oc7ahgvt4fxwi	58	31	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	59	1	Thomas	Thomas	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	2	Jefferson	Jefferson	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	3	University	University	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	4	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	59	5	Philadelphia	Philadelphia	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	6	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	59	7	PA	PA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	8	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	59	9	USA	USA	NNP
work_icsipe3itza57oc7ahgvt4fxwi	59	10	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	60	1	In	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	60	2	this	this	DT
work_icsipe3itza57oc7ahgvt4fxwi	60	3	study	study	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	4	we	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	60	5	seek	seek	VBP
work_icsipe3itza57oc7ahgvt4fxwi	60	6	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	60	7	identify	identify	VB
work_icsipe3itza57oc7ahgvt4fxwi	60	8	novel	novel	JJ
work_icsipe3itza57oc7ahgvt4fxwi	60	9	drug	drug	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	10	targets	target	NNS
work_icsipe3itza57oc7ahgvt4fxwi	60	11	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	60	12	induce	induce	VB
work_icsipe3itza57oc7ahgvt4fxwi	60	13	apoptosis	apoptosis	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	14	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	60	15	he-	he-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	60	16	patocellular	patocellular	JJ
work_icsipe3itza57oc7ahgvt4fxwi	60	17	carcinoma	carcinoma	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	18	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	60	19	HCC	HCC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	60	20	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	60	21	cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	60	22	thus	thus	RB
work_icsipe3itza57oc7ahgvt4fxwi	60	23	providing	provide	VBG
work_icsipe3itza57oc7ahgvt4fxwi	60	24	opportunities	opportunity	NNS
work_icsipe3itza57oc7ahgvt4fxwi	60	25	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	60	26	develop	develop	VB
work_icsipe3itza57oc7ahgvt4fxwi	60	27	novel	novel	JJ
work_icsipe3itza57oc7ahgvt4fxwi	60	28	treatments	treatment	NNS
work_icsipe3itza57oc7ahgvt4fxwi	60	29	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	60	30	improve	improve	VB
work_icsipe3itza57oc7ahgvt4fxwi	60	31	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	60	32	prognosis	prognosis	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	33	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	60	34	liver	liver	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	35	cancer	cancer	NN
work_icsipe3itza57oc7ahgvt4fxwi	60	36	patients	patient	NNS
work_icsipe3itza57oc7ahgvt4fxwi	60	37	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	61	1	Several	several	JJ
work_icsipe3itza57oc7ahgvt4fxwi	61	2	ap-	ap-	CD
work_icsipe3itza57oc7ahgvt4fxwi	61	3	optotic	optotic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	61	4	pathways	pathway	NNS
work_icsipe3itza57oc7ahgvt4fxwi	61	5	are	be	VBP
work_icsipe3itza57oc7ahgvt4fxwi	61	6	mediated	mediate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	61	7	through	through	IN
work_icsipe3itza57oc7ahgvt4fxwi	61	8	cleavage	cleavage	NN
work_icsipe3itza57oc7ahgvt4fxwi	61	9	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	61	10	Bid	Bid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	61	11	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	61	12	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	61	13	BH3	BH3	NNP
work_icsipe3itza57oc7ahgvt4fxwi	61	14	domain	domain	NN
work_icsipe3itza57oc7ahgvt4fxwi	61	15	-	-	,
work_icsipe3itza57oc7ahgvt4fxwi	61	16	only	only	RB
work_icsipe3itza57oc7ahgvt4fxwi	61	17	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	61	18	pro	pro	JJ
work_icsipe3itza57oc7ahgvt4fxwi	61	19	-	-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	61	20	apoptotic	apoptotic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	61	21	protein	protein	NN
work_icsipe3itza57oc7ahgvt4fxwi	61	22	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	61	23	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	61	24	produce	produce	VB
work_icsipe3itza57oc7ahgvt4fxwi	61	25	truncated	truncate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	61	26	Bid	Bid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	61	27	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	61	28	tBid	tBid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	61	29	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	61	30	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	62	1	tBid	tBid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	62	2	induces	induce	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	62	3	apoptosis	apoptosis	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	4	through	through	IN
work_icsipe3itza57oc7ahgvt4fxwi	62	5	induction	induction	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	6	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	62	7	outer	outer	JJ
work_icsipe3itza57oc7ahgvt4fxwi	62	8	mitochondrial	mitochondrial	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	9	membrane	membrane	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	10	(	(	-LRB-
work_icsipe3itza57oc7ahgvt4fxwi	62	11	OMM	OMM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	62	12	)	)	-RRB-
work_icsipe3itza57oc7ahgvt4fxwi	62	13	permeabilization	permeabilization	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	14	by	by	IN
work_icsipe3itza57oc7ahgvt4fxwi	62	15	activation	activation	NN
work_icsipe3itza57oc7ahgvt4fxwi	62	16	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	62	17	pro	pro	JJ
work_icsipe3itza57oc7ahgvt4fxwi	62	18	-	-	JJ
work_icsipe3itza57oc7ahgvt4fxwi	62	19	apoptotic	apoptotic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	62	20	Bak	Bak	NNP
work_icsipe3itza57oc7ahgvt4fxwi	62	21	that	that	WDT
work_icsipe3itza57oc7ahgvt4fxwi	62	22	resides	reside	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	62	23	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	62	24	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	62	25	OMM	OMM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	62	26	or	or	CC
work_icsipe3itza57oc7ahgvt4fxwi	62	27	cytoplasmic	cytoplasmic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	62	28	Bax	Bax	NNP
work_icsipe3itza57oc7ahgvt4fxwi	62	29	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	63	1	Due	due	IN
work_icsipe3itza57oc7ahgvt4fxwi	63	2	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	63	3	its	-PRON-	PRP$
work_icsipe3itza57oc7ahgvt4fxwi	63	4	localization	localization	NN
work_icsipe3itza57oc7ahgvt4fxwi	63	5	,	,	,
work_icsipe3itza57oc7ahgvt4fxwi	63	6	Bak	Bak	NNP
work_icsipe3itza57oc7ahgvt4fxwi	63	7	can	can	MD
work_icsipe3itza57oc7ahgvt4fxwi	63	8	mediate	mediate	VB
work_icsipe3itza57oc7ahgvt4fxwi	63	9	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	63	10	early	early	JJ
work_icsipe3itza57oc7ahgvt4fxwi	63	11	phase	phase	NN
work_icsipe3itza57oc7ahgvt4fxwi	63	12	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	63	13	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	63	14	response	response	NN
work_icsipe3itza57oc7ahgvt4fxwi	63	15	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	63	16	tBid	tBid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	63	17	.	.	.
work_icsipe3itza57oc7ahgvt4fxwi	64	1	We	-PRON-	PRP
work_icsipe3itza57oc7ahgvt4fxwi	64	2	have	have	VBP
work_icsipe3itza57oc7ahgvt4fxwi	64	3	recently	recently	RB
work_icsipe3itza57oc7ahgvt4fxwi	64	4	demonstrated	demonstrate	VBN
work_icsipe3itza57oc7ahgvt4fxwi	64	5	that	that	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	6	OMM	OMM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	7	targeting	targeting	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	8	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	9	Bak	bak	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	10	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	11	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	12	sensitivity	sensitivity	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	13	to	to	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	14	tBid	tBid	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	15	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	64	16	induced	induce	VBN
work_icsipe3itza57oc7ahgvt4fxwi	64	17	OMM	OMM	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	18	permeabilization	permeabilization	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	19	is	be	VBZ
work_icsipe3itza57oc7ahgvt4fxwi	64	20	dependent	dependent	JJ
work_icsipe3itza57oc7ahgvt4fxwi	64	21	on	on	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	22	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	23	expression	expression	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	24	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	25	A	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	26	Step	step	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	27	Forward	forward	RB
work_icsipe3itza57oc7ahgvt4fxwi	64	28	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	29	Understanding	understand	VBG
work_icsipe3itza57oc7ahgvt4fxwi	64	30	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	31	Mechanism	Mechanism	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	32	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	33	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	34	Voltage	Voltage	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	35	-	-	HYPH
work_icsipe3itza57oc7ahgvt4fxwi	64	36	Gating	Gating	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	37	Novel	Novel	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	38	Mechanism	Mechanism	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	39	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	40	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	41	Respiration	Respiration	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	42	Control	Control	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	43	through	through	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	44	Competition	Competition	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	45	between	between	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	46	Hexokinase-2	Hexokinase-2	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	47	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	48	Tubulin	Tubulin	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	49	for	for	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	50	VDAC	VDAC	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	51	Binding	bind	VBG
work_icsipe3itza57oc7ahgvt4fxwi	64	52	Reprogramming	reprogramming	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	53	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	54	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	55	Ca2	ca2	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	56	+	+	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	57	Handling	handling	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	58	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	59	MICU1-Deficient	MICU1-Deficient	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	60	HeLa	HeLa	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	61	Cells	cell	NNS
work_icsipe3itza57oc7ahgvt4fxwi	64	62	MICU1-dependent	MICU1-dependent	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	63	Threshold	Threshold	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	64	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	65	Cooperativity	Cooperativity	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	66	of	of	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	67	Mitochondrial	Mitochondrial	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	68	Ca2	ca2	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	69	+	+	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	70	Uptake	uptake	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	71	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	72	the	the	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	73	Liver	Liver	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	74	Targeting	Targeting	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	75	Mcl-1	Mcl-1	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	76	and	and	CC
work_icsipe3itza57oc7ahgvt4fxwi	64	77	Bak	Bak	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	78	as	as	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	79	a	a	DT
work_icsipe3itza57oc7ahgvt4fxwi	64	80	Therapeutic	therapeutic	JJ
work_icsipe3itza57oc7ahgvt4fxwi	64	81	Tool	tool	NN
work_icsipe3itza57oc7ahgvt4fxwi	64	82	to	to	TO
work_icsipe3itza57oc7ahgvt4fxwi	64	83	Selectively	selectively	RB
work_icsipe3itza57oc7ahgvt4fxwi	64	84	Induce	induce	VB
work_icsipe3itza57oc7ahgvt4fxwi	64	85	Apoptosis	Apoptosis	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	86	in	in	IN
work_icsipe3itza57oc7ahgvt4fxwi	64	87	Hepaptocellualr	Hepaptocellualr	NNP
work_icsipe3itza57oc7ahgvt4fxwi	64	88	Carcinoma	Carcinoma	NNP