id	sid	tid	token	lemma	pos
work_ynnlban46ndsvo6vb56iybocpu	1	1	Is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	1	2	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	1	3	Activation	Activation	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	4	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	5	Closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	1	6	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	1	7	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	8	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	9	Closed	Closed	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	10	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	1	11	State	state	NN
work_ynnlban46ndsvo6vb56iybocpu	1	12	Inactivation	Inactivation	NNP
work_ynnlban46ndsvo6vb56iybocpu	1	13	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	2	1	Sunday	Sunday	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	2	3	February	February	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	4	3	3	CD
work_ynnlban46ndsvo6vb56iybocpu	2	5	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	2	6	2013	2013	CD
work_ynnlban46ndsvo6vb56iybocpu	2	7	127a	127a	NNPS
work_ynnlban46ndsvo6vb56iybocpu	2	8	650-Pos	650-pos	NN
work_ynnlban46ndsvo6vb56iybocpu	2	9	Board	Board	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	10	B419	B419	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	11	Access	Access	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	12	Constraints	Constraints	NNPS
work_ynnlban46ndsvo6vb56iybocpu	2	13	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	2	14	Binding	Binding	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	15	Energetics	Energetics	NNPS
work_ynnlban46ndsvo6vb56iybocpu	2	16	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	2	17	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	2	18	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	19	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	20	Inactivation	Inactivation	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	21	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	22	Gaurav	Gaurav	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	23	Venkataraman	Venkataraman	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	24	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	2	25	Deepa	Deepa	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	26	Srikumar	Srikumar	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	27	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	2	28	Miguel	Miguel	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	29	Holmgren	Holmgren	NNP
work_ynnlban46ndsvo6vb56iybocpu	2	30	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	3	1	NIH	NIH	NNP
work_ynnlban46ndsvo6vb56iybocpu	3	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	3	3	Bethesda	Bethesda	NNP
work_ynnlban46ndsvo6vb56iybocpu	3	4	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	3	5	MD	MD	NNP
work_ynnlban46ndsvo6vb56iybocpu	3	6	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	3	7	USA	USA	NNP
work_ynnlban46ndsvo6vb56iybocpu	3	8	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	4	1	Voltage	voltage	NN
work_ynnlban46ndsvo6vb56iybocpu	4	2	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	4	3	activated	activate	VBN
work_ynnlban46ndsvo6vb56iybocpu	4	4	potassium	potassium	NN
work_ynnlban46ndsvo6vb56iybocpu	4	5	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	4	6	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	4	7	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	4	8	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	4	9	open	open	VBP
work_ynnlban46ndsvo6vb56iybocpu	4	10	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	4	11	intracellular	intracellular	JJ
work_ynnlban46ndsvo6vb56iybocpu	4	12	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	4	13	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	4	14	re-	re-	RB
work_ynnlban46ndsvo6vb56iybocpu	4	15	sponse	sponse	NN
work_ynnlban46ndsvo6vb56iybocpu	4	16	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	4	17	changes	change	NNS
work_ynnlban46ndsvo6vb56iybocpu	4	18	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	4	19	transmembrane	transmembrane	JJ
work_ynnlban46ndsvo6vb56iybocpu	4	20	voltage	voltage	NN
work_ynnlban46ndsvo6vb56iybocpu	4	21	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	4	22	allowing	allow	VBG
work_ynnlban46ndsvo6vb56iybocpu	4	23	K	K	NNP
work_ynnlban46ndsvo6vb56iybocpu	4	24	þ	þ	NNP
work_ynnlban46ndsvo6vb56iybocpu	4	25	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	4	26	permeate	permeate	VB
work_ynnlban46ndsvo6vb56iybocpu	4	27	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	4	28	rates	rate	NNS
work_ynnlban46ndsvo6vb56iybocpu	4	29	near	near	IN
work_ynnlban46ndsvo6vb56iybocpu	4	30	diffusion	diffusion	NN
work_ynnlban46ndsvo6vb56iybocpu	4	31	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	5	1	In	in	IN
work_ynnlban46ndsvo6vb56iybocpu	5	2	some	some	DT
work_ynnlban46ndsvo6vb56iybocpu	5	3	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	5	4	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	5	5	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	5	6	permeation	permeation	NN
work_ynnlban46ndsvo6vb56iybocpu	5	7	can	can	MD
work_ynnlban46ndsvo6vb56iybocpu	5	8	be	be	VB
work_ynnlban46ndsvo6vb56iybocpu	5	9	interrupted	interrupt	VBN
work_ynnlban46ndsvo6vb56iybocpu	5	10	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	5	11	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	5	12	N	n	NN
work_ynnlban46ndsvo6vb56iybocpu	5	13	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	5	14	terminus	terminus	NN
work_ynnlban46ndsvo6vb56iybocpu	5	15	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	5	16	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	5	17	protein	protein	NN
work_ynnlban46ndsvo6vb56iybocpu	5	18	acting	act	VBG
work_ynnlban46ndsvo6vb56iybocpu	5	19	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	5	20	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	5	21	blocking	block	VBG
work_ynnlban46ndsvo6vb56iybocpu	5	22	particle	particle	NN
work_ynnlban46ndsvo6vb56iybocpu	5	23	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	5	24	binding	bind	VBG
work_ynnlban46ndsvo6vb56iybocpu	5	25	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	5	26	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	5	27	intracel-	intracel-	NNP
work_ynnlban46ndsvo6vb56iybocpu	5	28	lular	lular	JJ
work_ynnlban46ndsvo6vb56iybocpu	5	29	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	5	30	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	5	31	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	5	32	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	5	33	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	5	34	physically	physically	RB
work_ynnlban46ndsvo6vb56iybocpu	5	35	obstructing	obstruct	VBG
work_ynnlban46ndsvo6vb56iybocpu	5	36	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	5	37	permeation	permeation	NN
work_ynnlban46ndsvo6vb56iybocpu	5	38	pathway	pathway	NN
work_ynnlban46ndsvo6vb56iybocpu	5	39	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	6	1	Despite	despite	IN
work_ynnlban46ndsvo6vb56iybocpu	6	2	being	be	VBG
work_ynnlban46ndsvo6vb56iybocpu	6	3	tetramers	tetramer	NNS
work_ynnlban46ndsvo6vb56iybocpu	6	4	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	6	5	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	6	6	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	6	7	require	require	VBP
work_ynnlban46ndsvo6vb56iybocpu	6	8	only	only	RB
work_ynnlban46ndsvo6vb56iybocpu	6	9	one	one	CD
work_ynnlban46ndsvo6vb56iybocpu	6	10	bound	bind	VBN
work_ynnlban46ndsvo6vb56iybocpu	6	11	N	n	NN
work_ynnlban46ndsvo6vb56iybocpu	6	12	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	6	13	terminus	terminus	NN
work_ynnlban46ndsvo6vb56iybocpu	6	14	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	6	15	inactivate	inactivate	NN
work_ynnlban46ndsvo6vb56iybocpu	6	16	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	7	1	In	in	IN
work_ynnlban46ndsvo6vb56iybocpu	7	2	nature	nature	NN
work_ynnlban46ndsvo6vb56iybocpu	7	3	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	7	4	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	7	5	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	7	6	targeted	target	VBN
work_ynnlban46ndsvo6vb56iybocpu	7	7	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	7	8	RNA	RNA	NNP
work_ynnlban46ndsvo6vb56iybocpu	7	9	editing	editing	NN
work_ynnlban46ndsvo6vb56iybocpu	7	10	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	7	11	which	which	WDT
work_ynnlban46ndsvo6vb56iybocpu	7	12	converts	convert	VBZ
work_ynnlban46ndsvo6vb56iybocpu	7	13	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	7	14	isoleucine	isoleucine	NN
work_ynnlban46ndsvo6vb56iybocpu	7	15	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	7	16	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	7	17	intracellular	intracellular	JJ
work_ynnlban46ndsvo6vb56iybocpu	7	18	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	7	19	into	into	IN
work_ynnlban46ndsvo6vb56iybocpu	7	20	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	7	21	valine	valine	NN
work_ynnlban46ndsvo6vb56iybocpu	7	22	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	8	1	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	8	2	functional	functional	JJ
work_ynnlban46ndsvo6vb56iybocpu	8	3	conse-	conse-	NN
work_ynnlban46ndsvo6vb56iybocpu	8	4	quence	quence	NN
work_ynnlban46ndsvo6vb56iybocpu	8	5	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	8	6	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	8	7	large	large	JJ
work_ynnlban46ndsvo6vb56iybocpu	8	8	increase	increase	NN
work_ynnlban46ndsvo6vb56iybocpu	8	9	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	8	10	unbinding	unbinding	JJ
work_ynnlban46ndsvo6vb56iybocpu	8	11	kinetics	kinetic	NNS
work_ynnlban46ndsvo6vb56iybocpu	8	12	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	9	1	How	how	WRB
work_ynnlban46ndsvo6vb56iybocpu	9	2	does	do	VBZ
work_ynnlban46ndsvo6vb56iybocpu	9	3	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	9	4	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	9	5	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	9	6	wall	wall	NN
work_ynnlban46ndsvo6vb56iybocpu	9	7	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	9	8	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	9	9	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	9	10	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	9	11	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	9	12	contribute	contribute	VBP
work_ynnlban46ndsvo6vb56iybocpu	9	13	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	9	14	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	9	15	increase	increase	NN
work_ynnlban46ndsvo6vb56iybocpu	9	16	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	9	17	unbinding	unbinding	JJ
work_ynnlban46ndsvo6vb56iybocpu	9	18	kinetics	kinetic	NNS
work_ynnlban46ndsvo6vb56iybocpu	9	19	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	9	20	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	9	21	single	single	JJ
work_ynnlban46ndsvo6vb56iybocpu	9	22	bound	bind	VBN
work_ynnlban46ndsvo6vb56iybocpu	9	23	N	n	NN
work_ynnlban46ndsvo6vb56iybocpu	9	24	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	9	25	terminus	terminus	NN
work_ynnlban46ndsvo6vb56iybocpu	9	26	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	10	1	To	to	TO
work_ynnlban46ndsvo6vb56iybocpu	10	2	address	address	VB
work_ynnlban46ndsvo6vb56iybocpu	10	3	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	10	4	question	question	NN
work_ynnlban46ndsvo6vb56iybocpu	10	5	we	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	10	6	made	make	VBD
work_ynnlban46ndsvo6vb56iybocpu	10	7	con-	con-	NN
work_ynnlban46ndsvo6vb56iybocpu	10	8	catenated	catenate	VBD
work_ynnlban46ndsvo6vb56iybocpu	10	9	Shaker	Shaker	NNP
work_ynnlban46ndsvo6vb56iybocpu	10	10	heterotetramers	heterotetramer	NNS
work_ynnlban46ndsvo6vb56iybocpu	10	11	consisting	consist	VBG
work_ynnlban46ndsvo6vb56iybocpu	10	12	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	10	13	only	only	RB
work_ynnlban46ndsvo6vb56iybocpu	10	14	one	one	CD
work_ynnlban46ndsvo6vb56iybocpu	10	15	free	free	JJ
work_ynnlban46ndsvo6vb56iybocpu	10	16	N	n	NN
work_ynnlban46ndsvo6vb56iybocpu	10	17	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	10	18	terminus	terminus	NN
work_ynnlban46ndsvo6vb56iybocpu	10	19	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	10	20	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	10	21	single	single	JJ
work_ynnlban46ndsvo6vb56iybocpu	10	22	isoleucine	isoleucine	NN
work_ynnlban46ndsvo6vb56iybocpu	10	23	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	10	24	valine	valine	NN
work_ynnlban46ndsvo6vb56iybocpu	10	25	mutation	mutation	NN
work_ynnlban46ndsvo6vb56iybocpu	10	26	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	10	27	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	10	28	470	470	CD
work_ynnlban46ndsvo6vb56iybocpu	10	29	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	10	30	I470V	i470v	CD
work_ynnlban46ndsvo6vb56iybocpu	10	31	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	10	32	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	10	33	mimicking	mimic	VBG
work_ynnlban46ndsvo6vb56iybocpu	10	34	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	10	35	RNA	RNA	NNP
work_ynnlban46ndsvo6vb56iybocpu	10	36	editing	editing	NN
work_ynnlban46ndsvo6vb56iybocpu	10	37	site	site	NN
work_ynnlban46ndsvo6vb56iybocpu	10	38	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	10	39	humans	human	NNS
work_ynnlban46ndsvo6vb56iybocpu	10	40	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	10	41	rodents	rodent	NNS
work_ynnlban46ndsvo6vb56iybocpu	10	42	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	11	1	Surprisingly	surprisingly	RB
work_ynnlban46ndsvo6vb56iybocpu	11	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	11	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	11	4	rate	rate	NN
work_ynnlban46ndsvo6vb56iybocpu	11	5	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	11	6	unbinding	unbinding	JJ
work_ynnlban46ndsvo6vb56iybocpu	11	7	was	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	11	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	11	9	same	same	JJ
work_ynnlban46ndsvo6vb56iybocpu	11	10	for	for	IN
work_ynnlban46ndsvo6vb56iybocpu	11	11	individual	individual	JJ
work_ynnlban46ndsvo6vb56iybocpu	11	12	I470V	i470v	CD
work_ynnlban46ndsvo6vb56iybocpu	11	13	mutations	mutation	NNS
work_ynnlban46ndsvo6vb56iybocpu	11	14	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	11	15	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	11	16	wall	wall	NN
work_ynnlban46ndsvo6vb56iybocpu	11	17	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	11	18	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	11	19	corresponded	correspond	VBD
work_ynnlban46ndsvo6vb56iybocpu	11	20	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	11	21	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	11	22	decrease	decrease	NN
work_ynnlban46ndsvo6vb56iybocpu	11	23	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	11	24	binding	bind	VBG
work_ynnlban46ndsvo6vb56iybocpu	11	25	energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	11	26	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	11	27	about	about	RB
work_ynnlban46ndsvo6vb56iybocpu	11	28	0.4	0.4	CD
work_ynnlban46ndsvo6vb56iybocpu	11	29	RT	RT	NNP
work_ynnlban46ndsvo6vb56iybocpu	11	30	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	12	1	In	in	IN
work_ynnlban46ndsvo6vb56iybocpu	12	2	fact	fact	NN
work_ynnlban46ndsvo6vb56iybocpu	12	3	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	12	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	12	5	binding	bind	VBG
work_ynnlban46ndsvo6vb56iybocpu	12	6	energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	12	7	de-	de-	PRP
work_ynnlban46ndsvo6vb56iybocpu	12	8	creased	crease	VBN
work_ynnlban46ndsvo6vb56iybocpu	12	9	linearly	linearly	RB
work_ynnlban46ndsvo6vb56iybocpu	12	10	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	12	11	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	12	12	function	function	NN
work_ynnlban46ndsvo6vb56iybocpu	12	13	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	12	14	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	12	15	number	number	NN
work_ynnlban46ndsvo6vb56iybocpu	12	16	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	12	17	I470V	i470v	CD
work_ynnlban46ndsvo6vb56iybocpu	12	18	mutated	mutate	VBN
work_ynnlban46ndsvo6vb56iybocpu	12	19	subunits	subunit	NNS
work_ynnlban46ndsvo6vb56iybocpu	12	20	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	13	1	These	these	DT
work_ynnlban46ndsvo6vb56iybocpu	13	2	results	result	NNS
work_ynnlban46ndsvo6vb56iybocpu	13	3	suggest	suggest	VBP
work_ynnlban46ndsvo6vb56iybocpu	13	4	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	13	5	despite	despite	IN
work_ynnlban46ndsvo6vb56iybocpu	13	6	being	be	VBG
work_ynnlban46ndsvo6vb56iybocpu	13	7	tethered	tether	VBN
work_ynnlban46ndsvo6vb56iybocpu	13	8	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	13	9	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	13	10	particular	particular	JJ
work_ynnlban46ndsvo6vb56iybocpu	13	11	subunit	subunit	NN
work_ynnlban46ndsvo6vb56iybocpu	13	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	13	13	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	13	14	single	single	JJ
work_ynnlban46ndsvo6vb56iybocpu	13	15	in-	in-	JJ
work_ynnlban46ndsvo6vb56iybocpu	13	16	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	13	17	particle	particle	NN
work_ynnlban46ndsvo6vb56iybocpu	13	18	has	have	VBZ
work_ynnlban46ndsvo6vb56iybocpu	13	19	sufficient	sufficient	JJ
work_ynnlban46ndsvo6vb56iybocpu	13	20	freedom	freedom	NN
work_ynnlban46ndsvo6vb56iybocpu	13	21	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	13	22	interact	interact	VB
work_ynnlban46ndsvo6vb56iybocpu	13	23	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	13	24	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	13	25	470	470	CD
work_ynnlban46ndsvo6vb56iybocpu	13	26	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	13	27	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	13	28	subunit	subunit	NN
work_ynnlban46ndsvo6vb56iybocpu	13	29	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	13	30	roughly	roughly	RB
work_ynnlban46ndsvo6vb56iybocpu	13	31	equal	equal	JJ
work_ynnlban46ndsvo6vb56iybocpu	13	32	probability	probability	NN
work_ynnlban46ndsvo6vb56iybocpu	13	33	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	14	1	Where	where	WRB
work_ynnlban46ndsvo6vb56iybocpu	14	2	does	do	VBZ
work_ynnlban46ndsvo6vb56iybocpu	14	3	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	14	4	freedom	freedom	NN
work_ynnlban46ndsvo6vb56iybocpu	14	5	come	come	VB
work_ynnlban46ndsvo6vb56iybocpu	14	6	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	14	7	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	15	1	It	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	15	2	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	15	3	expected	expect	VBN
work_ynnlban46ndsvo6vb56iybocpu	15	4	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	15	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	15	6	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	15	7	gates	gate	NNS
work_ynnlban46ndsvo6vb56iybocpu	15	8	enter	enter	VBP
work_ynnlban46ndsvo6vb56iybocpu	15	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	15	10	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	15	11	through	through	IN
work_ynnlban46ndsvo6vb56iybocpu	15	12	lateral	lateral	JJ
work_ynnlban46ndsvo6vb56iybocpu	15	13	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	15	14	windows	window	NNS
work_ynnlban46ndsvo6vb56iybocpu	15	15	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	15	16	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	15	17	similarly	similarly	RB
work_ynnlban46ndsvo6vb56iybocpu	15	18	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	15	19	K	K	NNP
work_ynnlban46ndsvo6vb56iybocpu	15	20	þ	þ	NNP
work_ynnlban46ndsvo6vb56iybocpu	15	21	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	16	1	Can	Can	MD
work_ynnlban46ndsvo6vb56iybocpu	16	2	our	-PRON-	PRP$
work_ynnlban46ndsvo6vb56iybocpu	16	3	single	single	JJ
work_ynnlban46ndsvo6vb56iybocpu	16	4	tethered	tethered	JJ
work_ynnlban46ndsvo6vb56iybocpu	16	5	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	16	6	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	16	7	enter	enter	VBP
work_ynnlban46ndsvo6vb56iybocpu	16	8	through	through	IN
work_ynnlban46ndsvo6vb56iybocpu	16	9	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	16	10	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	16	11	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	16	12	four	four	CD
work_ynnlban46ndsvo6vb56iybocpu	16	13	windows	window	NNS
work_ynnlban46ndsvo6vb56iybocpu	16	14	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	16	15	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	16	16	protein	protein	NN
work_ynnlban46ndsvo6vb56iybocpu	16	17	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	17	1	We	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	17	2	will	will	MD
work_ynnlban46ndsvo6vb56iybocpu	17	3	address	address	VB
work_ynnlban46ndsvo6vb56iybocpu	17	4	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	17	5	question	question	NN
work_ynnlban46ndsvo6vb56iybocpu	17	6	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	17	7	making	make	VBG
work_ynnlban46ndsvo6vb56iybocpu	17	8	individual	individual	JJ
work_ynnlban46ndsvo6vb56iybocpu	17	9	cysteine	cysteine	NN
work_ynnlban46ndsvo6vb56iybocpu	17	10	mutations	mutation	NNS
work_ynnlban46ndsvo6vb56iybocpu	17	11	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	17	12	each	each	DT
work_ynnlban46ndsvo6vb56iybocpu	17	13	window	window	NN
work_ynnlban46ndsvo6vb56iybocpu	17	14	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	17	15	testing	test	VBG
work_ynnlban46ndsvo6vb56iybocpu	17	16	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	17	17	inac-	inac-	NNP
work_ynnlban46ndsvo6vb56iybocpu	17	18	tivation	tivation	NN
work_ynnlban46ndsvo6vb56iybocpu	17	19	gate	gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	17	20	’s	’s	POS
work_ynnlban46ndsvo6vb56iybocpu	17	21	binding	bind	VBG
work_ynnlban46ndsvo6vb56iybocpu	17	22	kinetics	kinetic	NNS
work_ynnlban46ndsvo6vb56iybocpu	17	23	after	after	IN
work_ynnlban46ndsvo6vb56iybocpu	17	24	chemical	chemical	JJ
work_ynnlban46ndsvo6vb56iybocpu	17	25	modification	modification	NN
work_ynnlban46ndsvo6vb56iybocpu	17	26	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	18	1	651-Pos	651-Pos	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	2	Board	Board	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	3	B420	B420	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	4	Gating	Gating	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	5	Interactions	Interactions	NNPS
work_ynnlban46ndsvo6vb56iybocpu	18	6	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	18	7	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	18	8	Cytoplasmic	cytoplasmic	JJ
work_ynnlban46ndsvo6vb56iybocpu	18	9	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	10	Domain	Domain	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	11	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	18	12	Pore	Pore	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	13	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	18	14	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	18	15	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	16	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	17	Brian	Brian	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	18	Urbani	Urbani	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	19	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	18	20	Manuel	Manuel	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	21	Covarrubias	Covarrubias	NNP
work_ynnlban46ndsvo6vb56iybocpu	18	22	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	19	1	Jefferson	Jefferson	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	2	Medical	Medical	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	3	College	College	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	4	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	19	5	Thomas	Thomas	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	6	Jefferson	Jefferson	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	7	University	University	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	8	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	19	9	Philadelphia	Philadelphia	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	10	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	19	11	PA	PA	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	19	13	USA	USA	NNP
work_ynnlban46ndsvo6vb56iybocpu	19	14	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	20	1	Whereas	whereas	IN
work_ynnlban46ndsvo6vb56iybocpu	20	2	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	20	3	gating	gate	VBG
work_ynnlban46ndsvo6vb56iybocpu	20	4	roles	role	NNS
work_ynnlban46ndsvo6vb56iybocpu	20	5	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	20	6	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	20	7	voltage	voltage	NN
work_ynnlban46ndsvo6vb56iybocpu	20	8	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	20	9	sensing	sensing	NN
work_ynnlban46ndsvo6vb56iybocpu	20	10	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	20	11	pore	pore	NN
work_ynnlban46ndsvo6vb56iybocpu	20	12	domains	domain	NNS
work_ynnlban46ndsvo6vb56iybocpu	20	13	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	20	14	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	20	15	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	20	16	have	have	VBP
work_ynnlban46ndsvo6vb56iybocpu	20	17	been	be	VBN
work_ynnlban46ndsvo6vb56iybocpu	20	18	extensively	extensively	RB
work_ynnlban46ndsvo6vb56iybocpu	20	19	investigated	investigate	VBN
work_ynnlban46ndsvo6vb56iybocpu	20	20	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	20	21	much	much	RB
work_ynnlban46ndsvo6vb56iybocpu	20	22	less	less	RBR
work_ynnlban46ndsvo6vb56iybocpu	20	23	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	20	24	known	know	VBN
work_ynnlban46ndsvo6vb56iybocpu	20	25	about	about	IN
work_ynnlban46ndsvo6vb56iybocpu	20	26	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	20	27	mechanisms	mechanism	NNS
work_ynnlban46ndsvo6vb56iybocpu	20	28	governing	govern	VBG
work_ynnlban46ndsvo6vb56iybocpu	20	29	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	20	30	regulation	regulation	NN
work_ynnlban46ndsvo6vb56iybocpu	20	31	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	20	32	gating	gate	VBG
work_ynnlban46ndsvo6vb56iybocpu	20	33	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	20	34	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	20	35	cytoplasmic	cytoplasmic	JJ
work_ynnlban46ndsvo6vb56iybocpu	20	36	T1	t1	NN
work_ynnlban46ndsvo6vb56iybocpu	20	37	domain	domain	NN
work_ynnlban46ndsvo6vb56iybocpu	20	38	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	21	1	Previous	previous	JJ
work_ynnlban46ndsvo6vb56iybocpu	21	2	work	work	NN
work_ynnlban46ndsvo6vb56iybocpu	21	3	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	21	4	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	21	5	lab	lab	NN
work_ynnlban46ndsvo6vb56iybocpu	21	6	strongly	strongly	RB
work_ynnlban46ndsvo6vb56iybocpu	21	7	suggests	suggest	VBZ
work_ynnlban46ndsvo6vb56iybocpu	21	8	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	21	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	21	10	Kv4.1	Kv4.1	NNP
work_ynnlban46ndsvo6vb56iybocpu	21	11	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	21	12	domain	domain	NN
work_ynnlban46ndsvo6vb56iybocpu	21	13	un-	un-	JJ
work_ynnlban46ndsvo6vb56iybocpu	21	14	dergoes	dergoe	VBZ
work_ynnlban46ndsvo6vb56iybocpu	21	15	conformational	conformational	JJ
work_ynnlban46ndsvo6vb56iybocpu	21	16	changes	change	NNS
work_ynnlban46ndsvo6vb56iybocpu	21	17	directly	directly	RB
work_ynnlban46ndsvo6vb56iybocpu	21	18	linked	link	VBN
work_ynnlban46ndsvo6vb56iybocpu	21	19	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	21	20	gating	gate	VBG
work_ynnlban46ndsvo6vb56iybocpu	21	21	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	21	22	J.	J.	NNP
work_ynnlban46ndsvo6vb56iybocpu	21	23	Gen.	Gen.	NNP
work_ynnlban46ndsvo6vb56iybocpu	22	1	Physiol	Physiol	NNP
work_ynnlban46ndsvo6vb56iybocpu	22	2	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	22	3	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	22	4	127:391	127:391	CD
work_ynnlban46ndsvo6vb56iybocpu	22	5	-	-	SYM
work_ynnlban46ndsvo6vb56iybocpu	22	6	400	400	CD
work_ynnlban46ndsvo6vb56iybocpu	22	7	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	22	8	2006	2006	CD
work_ynnlban46ndsvo6vb56iybocpu	22	9	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	22	10	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	22	11	however	however	RB
work_ynnlban46ndsvo6vb56iybocpu	22	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	22	13	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	22	14	structural	structural	JJ
work_ynnlban46ndsvo6vb56iybocpu	22	15	basis	basis	NN
work_ynnlban46ndsvo6vb56iybocpu	22	16	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	22	17	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	22	18	communication	communication	NN
work_ynnlban46ndsvo6vb56iybocpu	22	19	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	22	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	22	21	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	22	22	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	22	23	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	22	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	22	25	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	22	26	domain	domain	NN
work_ynnlban46ndsvo6vb56iybocpu	22	27	has	have	VBZ
work_ynnlban46ndsvo6vb56iybocpu	22	28	remained	remain	VBN
work_ynnlban46ndsvo6vb56iybocpu	22	29	elusive	elusive	JJ
work_ynnlban46ndsvo6vb56iybocpu	22	30	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	23	1	To	to	TO
work_ynnlban46ndsvo6vb56iybocpu	23	2	tackle	tackle	VB
work_ynnlban46ndsvo6vb56iybocpu	23	3	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	23	4	problem	problem	NN
work_ynnlban46ndsvo6vb56iybocpu	23	5	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	23	6	we	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	23	7	applied	apply	VBD
work_ynnlban46ndsvo6vb56iybocpu	23	8	cysteine	cysteine	JJ
work_ynnlban46ndsvo6vb56iybocpu	23	9	scanning	scanning	NN
work_ynnlban46ndsvo6vb56iybocpu	23	10	mutagenesis	mutagenesis	NN
work_ynnlban46ndsvo6vb56iybocpu	23	11	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	23	12	voltage-	voltage-	NN
work_ynnlban46ndsvo6vb56iybocpu	23	13	clamp	clamp	NN
work_ynnlban46ndsvo6vb56iybocpu	23	14	electrophysiology	electrophysiology	NN
work_ynnlban46ndsvo6vb56iybocpu	23	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	23	16	double	double	JJ
work_ynnlban46ndsvo6vb56iybocpu	23	17	mutant	mutant	JJ
work_ynnlban46ndsvo6vb56iybocpu	23	18	cycle	cycle	NN
work_ynnlban46ndsvo6vb56iybocpu	23	19	analysis	analysis	NN
work_ynnlban46ndsvo6vb56iybocpu	23	20	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	23	21	DMCA	DMCA	NNP
work_ynnlban46ndsvo6vb56iybocpu	23	22	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	23	23	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	23	24	oxidizing	oxidize	VBG
work_ynnlban46ndsvo6vb56iybocpu	23	25	reagents	reagent	NNS
work_ynnlban46ndsvo6vb56iybocpu	23	26	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	23	27	probe	probe	VB
work_ynnlban46ndsvo6vb56iybocpu	23	28	specific	specific	JJ
work_ynnlban46ndsvo6vb56iybocpu	23	29	interactions	interaction	NNS
work_ynnlban46ndsvo6vb56iybocpu	23	30	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	23	31	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	23	32	cytoplasmic	cytoplasmic	JJ
work_ynnlban46ndsvo6vb56iybocpu	23	33	T1	t1	NN
work_ynnlban46ndsvo6vb56iybocpu	23	34	domain	domain	NN
work_ynnlban46ndsvo6vb56iybocpu	23	35	L4	L4	NNP
work_ynnlban46ndsvo6vb56iybocpu	23	36	helix	helix	NN
work_ynnlban46ndsvo6vb56iybocpu	23	37	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	23	38	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	23	39	S4-S5	S4-S5	NNP
work_ynnlban46ndsvo6vb56iybocpu	23	40	linker	linker	NN
work_ynnlban46ndsvo6vb56iybocpu	23	41	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	23	42	S6	s6	NN
work_ynnlban46ndsvo6vb56iybocpu	23	43	tail	tail	NN
work_ynnlban46ndsvo6vb56iybocpu	23	44	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	24	1	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	24	2	energetic	energetic	JJ
work_ynnlban46ndsvo6vb56iybocpu	24	3	impact	impact	NN
work_ynnlban46ndsvo6vb56iybocpu	24	4	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	24	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	24	6	mutations	mutation	NNS
work_ynnlban46ndsvo6vb56iybocpu	24	7	on	on	IN
work_ynnlban46ndsvo6vb56iybocpu	24	8	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	24	9	gating	gating	NN
work_ynnlban46ndsvo6vb56iybocpu	24	10	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	24	11	apparently	apparently	RB
work_ynnlban46ndsvo6vb56iybocpu	24	12	small	small	JJ
work_ynnlban46ndsvo6vb56iybocpu	24	13	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	25	1	By	by	IN
work_ynnlban46ndsvo6vb56iybocpu	25	2	comparison	comparison	NN
work_ynnlban46ndsvo6vb56iybocpu	25	3	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	25	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	25	5	energetic	energetic	JJ
work_ynnlban46ndsvo6vb56iybocpu	25	6	impact	impact	NN
work_ynnlban46ndsvo6vb56iybocpu	25	7	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	25	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	25	9	mutations	mutation	NNS
work_ynnlban46ndsvo6vb56iybocpu	25	10	on	on	IN
work_ynnlban46ndsvo6vb56iybocpu	25	11	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	25	12	gating	gating	NN
work_ynnlban46ndsvo6vb56iybocpu	25	13	was	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	25	14	significantly	significantly	RB
work_ynnlban46ndsvo6vb56iybocpu	25	15	greater	great	JJR
work_ynnlban46ndsvo6vb56iybocpu	25	16	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	26	1	DMCA	DMCA	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	2	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	26	3	K141C(L4)þA422C(S6	K141C(L4)þA422C(S6	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	4	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	26	5	revealed	reveal	VBD
work_ynnlban46ndsvo6vb56iybocpu	26	6	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	26	7	significant	significant	JJ
work_ynnlban46ndsvo6vb56iybocpu	26	8	interaction	interaction	NN
work_ynnlban46ndsvo6vb56iybocpu	26	9	energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	26	10	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	26	11	4	4	CD
work_ynnlban46ndsvo6vb56iybocpu	26	12	kcal/	kcal/	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	13	mol	mol	NN
work_ynnlban46ndsvo6vb56iybocpu	26	14	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	26	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	26	16	which	which	WDT
work_ynnlban46ndsvo6vb56iybocpu	26	17	suggests	suggest	VBZ
work_ynnlban46ndsvo6vb56iybocpu	26	18	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	26	19	interaction	interaction	NN
work_ynnlban46ndsvo6vb56iybocpu	26	20	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	26	21	K141	K141	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	22	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	26	23	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	26	24	L4	L4	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	25	helix	helix	NN
work_ynnlban46ndsvo6vb56iybocpu	26	26	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	26	27	A422	a422	NN
work_ynnlban46ndsvo6vb56iybocpu	26	28	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	26	29	S6	S6	NNP
work_ynnlban46ndsvo6vb56iybocpu	26	30	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	27	1	Supporting	support	VBG
work_ynnlban46ndsvo6vb56iybocpu	27	2	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	27	3	possibility	possibility	NN
work_ynnlban46ndsvo6vb56iybocpu	27	4	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	27	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	27	6	currents	current	NNS
work_ynnlban46ndsvo6vb56iybocpu	27	7	induced	induce	VBN
work_ynnlban46ndsvo6vb56iybocpu	27	8	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	27	9	K141C(L4)þ	K141C(L4)þ	NNP
work_ynnlban46ndsvo6vb56iybocpu	27	10	A422C(S6	A422C(S6	NNP
work_ynnlban46ndsvo6vb56iybocpu	27	11	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	27	12	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	27	13	inhibited	inhibit	VBN
work_ynnlban46ndsvo6vb56iybocpu	27	14	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	27	15	~65	~65	NFP
work_ynnlban46ndsvo6vb56iybocpu	27	16	%	%	NN
work_ynnlban46ndsvo6vb56iybocpu	27	17	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	27	18	control	control	NN
work_ynnlban46ndsvo6vb56iybocpu	27	19	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	27	20	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	27	21	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	27	22	oxidizing	oxidizing	JJ
work_ynnlban46ndsvo6vb56iybocpu	27	23	agent	agent	NN
work_ynnlban46ndsvo6vb56iybocpu	27	24	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	27	25	tBuHO2	tBuHO2	NNP
work_ynnlban46ndsvo6vb56iybocpu	27	26	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	27	27	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	27	28	whereas	whereas	IN
work_ynnlban46ndsvo6vb56iybocpu	27	29	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	27	30	single	single	JJ
work_ynnlban46ndsvo6vb56iybocpu	27	31	mutants	mutant	NNS
work_ynnlban46ndsvo6vb56iybocpu	27	32	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	27	33	not	not	RB
work_ynnlban46ndsvo6vb56iybocpu	27	34	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	27	35	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	27	36	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	27	37	effect	effect	NN
work_ynnlban46ndsvo6vb56iybocpu	27	38	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	27	39	reversed	reverse	VBN
work_ynnlban46ndsvo6vb56iybocpu	27	40	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	27	41	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	27	42	reducing	reduce	VBG
work_ynnlban46ndsvo6vb56iybocpu	27	43	agent	agent	NN
work_ynnlban46ndsvo6vb56iybocpu	27	44	DTT	DTT	NNP
work_ynnlban46ndsvo6vb56iybocpu	27	45	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	28	1	These	these	DT
work_ynnlban46ndsvo6vb56iybocpu	28	2	results	result	NNS
work_ynnlban46ndsvo6vb56iybocpu	28	3	indicate	indicate	VBP
work_ynnlban46ndsvo6vb56iybocpu	28	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	28	5	formation	formation	NN
work_ynnlban46ndsvo6vb56iybocpu	28	6	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	28	7	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	28	8	disulfide	disulfide	JJ
work_ynnlban46ndsvo6vb56iybocpu	28	9	bond	bond	NN
work_ynnlban46ndsvo6vb56iybocpu	28	10	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	28	11	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	28	12	interacting	interact	VBG
work_ynnlban46ndsvo6vb56iybocpu	28	13	side	side	NN
work_ynnlban46ndsvo6vb56iybocpu	28	14	chains	chain	NNS
work_ynnlban46ndsvo6vb56iybocpu	28	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	28	16	which	which	WDT
work_ynnlban46ndsvo6vb56iybocpu	28	17	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	28	18	consistent	consistent	JJ
work_ynnlban46ndsvo6vb56iybocpu	28	19	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	28	20	physical	physical	JJ
work_ynnlban46ndsvo6vb56iybocpu	28	21	interaction	interaction	NN
work_ynnlban46ndsvo6vb56iybocpu	28	22	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	28	23	K141(L4	K141(L4	NNP
work_ynnlban46ndsvo6vb56iybocpu	28	24	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	28	25	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	28	26	A422(S6	A422(S6	NNP
work_ynnlban46ndsvo6vb56iybocpu	28	27	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	28	28	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	29	1	Overall	overall	RB
work_ynnlban46ndsvo6vb56iybocpu	29	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	29	3	we	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	29	4	conclude	conclude	VBP
work_ynnlban46ndsvo6vb56iybocpu	29	5	that	that	DT
work_ynnlban46ndsvo6vb56iybocpu	29	6	regulation	regulation	NN
work_ynnlban46ndsvo6vb56iybocpu	29	7	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	29	8	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	29	9	gating	gate	VBG
work_ynnlban46ndsvo6vb56iybocpu	29	10	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	29	11	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	29	12	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	29	13	domain	domain	NN
work_ynnlban46ndsvo6vb56iybocpu	29	14	involves	involve	VBZ
work_ynnlban46ndsvo6vb56iybocpu	29	15	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	29	16	physical	physical	JJ
work_ynnlban46ndsvo6vb56iybocpu	29	17	interaction	interaction	NN
work_ynnlban46ndsvo6vb56iybocpu	29	18	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	29	19	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	29	20	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	29	21	L4	L4	NNP
work_ynnlban46ndsvo6vb56iybocpu	29	22	helix	helix	NN
work_ynnlban46ndsvo6vb56iybocpu	29	23	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	29	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	29	25	distal	distal	JJ
work_ynnlban46ndsvo6vb56iybocpu	29	26	segment	segment	NN
work_ynnlban46ndsvo6vb56iybocpu	29	27	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	29	28	S6	s6	NN
work_ynnlban46ndsvo6vb56iybocpu	29	29	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	30	1	Supported	support	VBN
work_ynnlban46ndsvo6vb56iybocpu	30	2	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	30	3	NIH	NIH	NNP
work_ynnlban46ndsvo6vb56iybocpu	30	4	grant	grant	NN
work_ynnlban46ndsvo6vb56iybocpu	30	5	R01	R01	NNP
work_ynnlban46ndsvo6vb56iybocpu	30	6	NS032337	NS032337	NNP
work_ynnlban46ndsvo6vb56iybocpu	30	7	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	30	8	MC	MC	NNP
work_ynnlban46ndsvo6vb56iybocpu	30	9	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	30	10	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	31	1	652-Pos	652-Pos	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	2	Board	Board	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	3	B421	B421	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	4	Is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	31	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	31	6	Activation	Activation	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	7	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	8	Closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	31	9	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	31	10	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	11	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	12	Closed	Closed	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	13	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	31	14	State	state	NN
work_ynnlban46ndsvo6vb56iybocpu	31	15	Inactivation	Inactivation	NNP
work_ynnlban46ndsvo6vb56iybocpu	31	16	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	32	1	Jeffrey	Jeffrey	NNP
work_ynnlban46ndsvo6vb56iybocpu	32	2	D.	D.	NNP
work_ynnlban46ndsvo6vb56iybocpu	32	3	Fineberg	Fineberg	NNP
work_ynnlban46ndsvo6vb56iybocpu	32	4	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	32	5	Manuel	Manuel	NNP
work_ynnlban46ndsvo6vb56iybocpu	32	6	Covarrubias	Covarrubias	NNP
work_ynnlban46ndsvo6vb56iybocpu	32	7	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	33	1	Thomas	Thomas	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	2	Jefferson	Jefferson	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	3	University	University	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	4	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	33	5	Philadelphia	Philadelphia	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	6	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	33	7	PA	PA	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	8	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	33	9	USA	USA	NNP
work_ynnlban46ndsvo6vb56iybocpu	33	10	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	34	1	Kv4.x	Kv4.x	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	2	channel	channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	3	complexes	complex	NNS
work_ynnlban46ndsvo6vb56iybocpu	34	4	including	include	VBG
work_ynnlban46ndsvo6vb56iybocpu	34	5	auxiliary	auxiliary	JJ
work_ynnlban46ndsvo6vb56iybocpu	34	6	subunits	subunit	NNS
work_ynnlban46ndsvo6vb56iybocpu	34	7	such	such	JJ
work_ynnlban46ndsvo6vb56iybocpu	34	8	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	34	9	DPP6-S	DPP6-S	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	10	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	34	11	KChIP1	KChIP1	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	12	undergo	undergo	VBP
work_ynnlban46ndsvo6vb56iybocpu	34	13	preferential	preferential	JJ
work_ynnlban46ndsvo6vb56iybocpu	34	14	closed	closed	JJ
work_ynnlban46ndsvo6vb56iybocpu	34	15	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	34	16	state	state	NN
work_ynnlban46ndsvo6vb56iybocpu	34	17	inactivation	inactivation	NN
work_ynnlban46ndsvo6vb56iybocpu	34	18	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	34	19	CSI	CSI	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	20	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	34	21	Baehring	baehring	NN
work_ynnlban46ndsvo6vb56iybocpu	34	22	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	34	23	Covarrubias	Covarrubias	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	24	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	25	2011	2011	CD
work_ynnlban46ndsvo6vb56iybocpu	34	26	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	27	J	J	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	28	Physiol	Physiol	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	29	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	30	589.3:461	589.3:461	CD
work_ynnlban46ndsvo6vb56iybocpu	34	31	-	-	SYM
work_ynnlban46ndsvo6vb56iybocpu	34	32	479	479	CD
work_ynnlban46ndsvo6vb56iybocpu	34	33	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	34	34	Fineberg	Fineberg	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	35	et	et	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	36	al	al	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	37	.	.	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	38	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	39	2012	2012	CD
work_ynnlban46ndsvo6vb56iybocpu	34	40	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	41	J	J	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	42	Gen	Gen	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	43	Physiol	Physiol	NNP
work_ynnlban46ndsvo6vb56iybocpu	34	44	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	34	45	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	34	46	press	press	NN
work_ynnlban46ndsvo6vb56iybocpu	34	47	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	34	48	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	35	1	However	however	RB
work_ynnlban46ndsvo6vb56iybocpu	35	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	35	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	35	4	molecular	molecular	JJ
work_ynnlban46ndsvo6vb56iybocpu	35	5	basis	basis	NN
work_ynnlban46ndsvo6vb56iybocpu	35	6	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	35	7	CSI	CSI	NNP
work_ynnlban46ndsvo6vb56iybocpu	35	8	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	35	9	Kv4.x	Kv4.x	NNP
work_ynnlban46ndsvo6vb56iybocpu	35	10	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	35	11	remains	remain	VBZ
work_ynnlban46ndsvo6vb56iybocpu	35	12	poorly	poorly	RB
work_ynnlban46ndsvo6vb56iybocpu	35	13	understood	understand	VBN
work_ynnlban46ndsvo6vb56iybocpu	35	14	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	36	1	A	a	DT
work_ynnlban46ndsvo6vb56iybocpu	36	2	key	key	JJ
work_ynnlban46ndsvo6vb56iybocpu	36	3	unanswered	unanswered	JJ
work_ynnlban46ndsvo6vb56iybocpu	36	4	question	question	NN
work_ynnlban46ndsvo6vb56iybocpu	36	5	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	36	6	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	36	7	problem	problem	NN
work_ynnlban46ndsvo6vb56iybocpu	36	8	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	36	9	whether	whether	IN
work_ynnlban46ndsvo6vb56iybocpu	36	10	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	36	11	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	36	12	’s	’s	POS
work_ynnlban46ndsvo6vb56iybocpu	36	13	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	36	14	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	36	15	actually	actually	RB
work_ynnlban46ndsvo6vb56iybocpu	36	16	closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	36	17	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	36	18	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	36	19	CSI	CSI	NNP
work_ynnlban46ndsvo6vb56iybocpu	36	20	implies	imply	VBZ
work_ynnlban46ndsvo6vb56iybocpu	36	21	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	37	1	We	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	37	2	have	have	VBP
work_ynnlban46ndsvo6vb56iybocpu	37	3	previously	previously	RB
work_ynnlban46ndsvo6vb56iybocpu	37	4	proposed	propose	VBN
work_ynnlban46ndsvo6vb56iybocpu	37	5	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	37	6	CSI	CSI	NNP
work_ynnlban46ndsvo6vb56iybocpu	37	7	results	result	NNS
work_ynnlban46ndsvo6vb56iybocpu	37	8	when	when	WRB
work_ynnlban46ndsvo6vb56iybocpu	37	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	37	10	activated	activate	VBN
work_ynnlban46ndsvo6vb56iybocpu	37	11	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	37	12	fails	fail	VBZ
work_ynnlban46ndsvo6vb56iybocpu	37	13	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	37	14	open	open	VB
work_ynnlban46ndsvo6vb56iybocpu	37	15	or	or	CC
work_ynnlban46ndsvo6vb56iybocpu	37	16	simply	simply	RB
work_ynnlban46ndsvo6vb56iybocpu	37	17	prefers	prefer	NNS
work_ynnlban46ndsvo6vb56iybocpu	37	18	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	37	19	close	close	VB
work_ynnlban46ndsvo6vb56iybocpu	37	20	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	38	1	This	this	DT
work_ynnlban46ndsvo6vb56iybocpu	38	2	hypothesis	hypothesis	NN
work_ynnlban46ndsvo6vb56iybocpu	38	3	specifically	specifically	RB
work_ynnlban46ndsvo6vb56iybocpu	38	4	suggests	suggest	VBZ
work_ynnlban46ndsvo6vb56iybocpu	38	5	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	38	6	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	38	7	intra-	intra-	NNP
work_ynnlban46ndsvo6vb56iybocpu	38	8	cellular	cellular	JJ
work_ynnlban46ndsvo6vb56iybocpu	38	9	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	38	10	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	38	11	may	may	MD
work_ynnlban46ndsvo6vb56iybocpu	38	12	adopt	adopt	VB
work_ynnlban46ndsvo6vb56iybocpu	38	13	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	38	14	stable	stable	JJ
work_ynnlban46ndsvo6vb56iybocpu	38	15	closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	38	16	conformation	conformation	NN
work_ynnlban46ndsvo6vb56iybocpu	38	17	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	38	18	even	even	RB
work_ynnlban46ndsvo6vb56iybocpu	38	19	under	under	IN
work_ynnlban46ndsvo6vb56iybocpu	38	20	depolarized	depolarize	VBN
work_ynnlban46ndsvo6vb56iybocpu	38	21	conditions	condition	NNS
work_ynnlban46ndsvo6vb56iybocpu	38	22	that	that	WDT
work_ynnlban46ndsvo6vb56iybocpu	38	23	would	would	MD
work_ynnlban46ndsvo6vb56iybocpu	38	24	initially	initially	RB
work_ynnlban46ndsvo6vb56iybocpu	38	25	favor	favor	VB
work_ynnlban46ndsvo6vb56iybocpu	38	26	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	38	27	activated	activate	VBN
work_ynnlban46ndsvo6vb56iybocpu	38	28	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	38	29	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	38	30	up	up	RP
work_ynnlban46ndsvo6vb56iybocpu	38	31	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	38	32	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	38	33	state	state	NN
work_ynnlban46ndsvo6vb56iybocpu	38	34	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	38	35	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	38	36	voltage	voltage	NN
work_ynnlban46ndsvo6vb56iybocpu	38	37	sensors	sensor	NNS
work_ynnlban46ndsvo6vb56iybocpu	38	38	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	39	1	To	to	TO
work_ynnlban46ndsvo6vb56iybocpu	39	2	test	test	VB
work_ynnlban46ndsvo6vb56iybocpu	39	3	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	39	4	hypothesis	hypothesis	NN
work_ynnlban46ndsvo6vb56iybocpu	39	5	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	39	6	we	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	39	7	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	39	8	exploiting	exploit	VBG
work_ynnlban46ndsvo6vb56iybocpu	39	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	39	10	trapping	trap	VBG
work_ynnlban46ndsvo6vb56iybocpu	39	11	paradigm	paradigm	NN
work_ynnlban46ndsvo6vb56iybocpu	39	12	previously	previously	RB
work_ynnlban46ndsvo6vb56iybocpu	39	13	investigated	investigate	VBN
work_ynnlban46ndsvo6vb56iybocpu	39	14	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	39	15	Holmgren	Holmgren	NNP
work_ynnlban46ndsvo6vb56iybocpu	39	16	et	et	NNP
work_ynnlban46ndsvo6vb56iybocpu	39	17	al	al	NNP
work_ynnlban46ndsvo6vb56iybocpu	39	18	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	40	1	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	40	2	test	test	VB
work_ynnlban46ndsvo6vb56iybocpu	40	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	40	4	state	state	NN
work_ynnlban46ndsvo6vb56iybocpu	40	5	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	40	6	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	40	7	intracellular	intracellular	JJ
work_ynnlban46ndsvo6vb56iybocpu	40	8	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	40	9	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	40	10	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	40	11	1997	1997	CD
work_ynnlban46ndsvo6vb56iybocpu	40	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	40	13	J	J	NNP
work_ynnlban46ndsvo6vb56iybocpu	40	14	Gen	Gen	NNP
work_ynnlban46ndsvo6vb56iybocpu	40	15	Physiol	Physiol	NNP
work_ynnlban46ndsvo6vb56iybocpu	40	16	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	40	17	109:527	109:527	CD
work_ynnlban46ndsvo6vb56iybocpu	40	18	-	-	SYM
work_ynnlban46ndsvo6vb56iybocpu	40	19	535	535	CD
work_ynnlban46ndsvo6vb56iybocpu	40	20	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	40	21	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	41	1	Essentially	essentially	RB
work_ynnlban46ndsvo6vb56iybocpu	41	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	41	3	if	if	IN
work_ynnlban46ndsvo6vb56iybocpu	41	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	41	5	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	41	6	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	41	7	closes	close	VBZ
work_ynnlban46ndsvo6vb56iybocpu	41	8	behind	behind	IN
work_ynnlban46ndsvo6vb56iybocpu	41	9	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	41	10	quaternary	quaternary	NN
work_ynnlban46ndsvo6vb56iybocpu	41	11	ammonium	ammonium	NN
work_ynnlban46ndsvo6vb56iybocpu	41	12	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	41	13	QA	qa	NN
work_ynnlban46ndsvo6vb56iybocpu	41	14	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	41	15	blocker	blocker	NN
work_ynnlban46ndsvo6vb56iybocpu	41	16	inside	inside	IN
work_ynnlban46ndsvo6vb56iybocpu	41	17	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	41	18	pore	pore	NN
work_ynnlban46ndsvo6vb56iybocpu	41	19	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	41	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	41	21	blocker	blocker	NN
work_ynnlban46ndsvo6vb56iybocpu	41	22	can	can	MD
work_ynnlban46ndsvo6vb56iybocpu	41	23	not	not	RB
work_ynnlban46ndsvo6vb56iybocpu	41	24	exit	exit	VB
work_ynnlban46ndsvo6vb56iybocpu	41	25	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	41	26	pore	pore	NN
work_ynnlban46ndsvo6vb56iybocpu	41	27	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	41	28	effectively	effectively	RB
work_ynnlban46ndsvo6vb56iybocpu	41	29	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	41	30	it	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	41	31	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	41	32	trapped	trap	VBN
work_ynnlban46ndsvo6vb56iybocpu	41	33	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	42	1	We	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	42	2	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	42	3	expressing	express	VBG
work_ynnlban46ndsvo6vb56iybocpu	42	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	42	5	ternary	ternary	JJ
work_ynnlban46ndsvo6vb56iybocpu	42	6	Kv4.1	Kv4.1	NNP
work_ynnlban46ndsvo6vb56iybocpu	42	7	/	/	SYM
work_ynnlban46ndsvo6vb56iybocpu	42	8	I400C	I400C	NNP
work_ynnlban46ndsvo6vb56iybocpu	42	9	channels	channel	NNS
work_ynnlban46ndsvo6vb56iybocpu	42	10	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	42	11	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	42	12	mutation	mutation	NN
work_ynnlban46ndsvo6vb56iybocpu	42	13	favors	favor	VBZ
work_ynnlban46ndsvo6vb56iybocpu	42	14	trap-	trap-	JJ
work_ynnlban46ndsvo6vb56iybocpu	42	15	ping	ping	NN
work_ynnlban46ndsvo6vb56iybocpu	42	16	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	42	17	including	include	VBG
work_ynnlban46ndsvo6vb56iybocpu	42	18	DPP6-S	DPP6-S	NNP
work_ynnlban46ndsvo6vb56iybocpu	42	19	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	42	20	KChIP1	KChIP1	NNP
work_ynnlban46ndsvo6vb56iybocpu	42	21	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	42	22	Xenopus	Xenopus	NNP
work_ynnlban46ndsvo6vb56iybocpu	42	23	oocytes	oocyte	NNS
work_ynnlban46ndsvo6vb56iybocpu	42	24	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	43	1	Then	then	RB
work_ynnlban46ndsvo6vb56iybocpu	43	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	43	3	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	43	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	5	inside-	inside-	NN
work_ynnlban46ndsvo6vb56iybocpu	43	6	out	out	IN
work_ynnlban46ndsvo6vb56iybocpu	43	7	patch	patch	NN
work_ynnlban46ndsvo6vb56iybocpu	43	8	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	43	9	clamp	clamp	NN
work_ynnlban46ndsvo6vb56iybocpu	43	10	configuration	configuration	NN
work_ynnlban46ndsvo6vb56iybocpu	43	11	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	43	12	we	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	43	13	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	43	14	using	use	VBG
work_ynnlban46ndsvo6vb56iybocpu	43	15	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	43	16	computer	computer	NN
work_ynnlban46ndsvo6vb56iybocpu	43	17	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	43	18	controlled	control	VBN
work_ynnlban46ndsvo6vb56iybocpu	43	19	perfusion	perfusion	NN
work_ynnlban46ndsvo6vb56iybocpu	43	20	system	system	NN
work_ynnlban46ndsvo6vb56iybocpu	43	21	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	43	22	deliver	deliver	VB
work_ynnlban46ndsvo6vb56iybocpu	43	23	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	24	QA	qa	NN
work_ynnlban46ndsvo6vb56iybocpu	43	25	derivative	derivative	JJ
work_ynnlban46ndsvo6vb56iybocpu	43	26	decyltrimethylammonium	decyltrimethylammonium	NN
work_ynnlban46ndsvo6vb56iybocpu	43	27	bromide	bromide	NN
work_ynnlban46ndsvo6vb56iybocpu	43	28	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	43	29	C10	C10	NNP
work_ynnlban46ndsvo6vb56iybocpu	43	30	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	43	31	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	43	32	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	33	bath	bath	NN
work_ynnlban46ndsvo6vb56iybocpu	43	34	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	43	35	probe	probe	VB
work_ynnlban46ndsvo6vb56iybocpu	43	36	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	37	ability	ability	NN
work_ynnlban46ndsvo6vb56iybocpu	43	38	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	43	39	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	40	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	43	41	’s	’s	POS
work_ynnlban46ndsvo6vb56iybocpu	43	42	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	43	43	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	43	44	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	43	45	trap	trap	VB
work_ynnlban46ndsvo6vb56iybocpu	43	46	C10	C10	NNP
work_ynnlban46ndsvo6vb56iybocpu	43	47	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	43	48	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	43	49	closed	closed	JJ
work_ynnlban46ndsvo6vb56iybocpu	43	50	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	43	51	open	open	JJ
work_ynnlban46ndsvo6vb56iybocpu	43	52	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	43	53	inactivated	inactivated	JJ
work_ynnlban46ndsvo6vb56iybocpu	43	54	states	state	NNS
work_ynnlban46ndsvo6vb56iybocpu	43	55	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	44	1	Preliminary	preliminary	JJ
work_ynnlban46ndsvo6vb56iybocpu	44	2	results	result	NNS
work_ynnlban46ndsvo6vb56iybocpu	44	3	show	show	VBP
work_ynnlban46ndsvo6vb56iybocpu	44	4	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	44	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	44	6	trapping	trap	VBG
work_ynnlban46ndsvo6vb56iybocpu	44	7	paradigm	paradigm	NN
work_ynnlban46ndsvo6vb56iybocpu	44	8	may	may	MD
work_ynnlban46ndsvo6vb56iybocpu	44	9	yield	yield	VB
work_ynnlban46ndsvo6vb56iybocpu	44	10	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	44	11	answer	answer	NN
work_ynnlban46ndsvo6vb56iybocpu	44	12	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	44	13	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	44	14	central	central	JJ
work_ynnlban46ndsvo6vb56iybocpu	44	15	question	question	NN
work_ynnlban46ndsvo6vb56iybocpu	44	16	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	44	17	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	44	18	study	study	NN
work_ynnlban46ndsvo6vb56iybocpu	44	19	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	45	1	If	if	IN
work_ynnlban46ndsvo6vb56iybocpu	45	2	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	45	3	activation	activation	NN
work_ynnlban46ndsvo6vb56iybocpu	45	4	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	45	5	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	45	6	indeed	indeed	RB
work_ynnlban46ndsvo6vb56iybocpu	45	7	closed	closed	JJ
work_ynnlban46ndsvo6vb56iybocpu	45	8	during	during	IN
work_ynnlban46ndsvo6vb56iybocpu	45	9	CSI	CSI	NNP
work_ynnlban46ndsvo6vb56iybocpu	45	10	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	45	11	C10	C10	NNP
work_ynnlban46ndsvo6vb56iybocpu	45	12	trapping	trapping	NN
work_ynnlban46ndsvo6vb56iybocpu	45	13	will	will	MD
work_ynnlban46ndsvo6vb56iybocpu	45	14	only	only	RB
work_ynnlban46ndsvo6vb56iybocpu	45	15	occur	occur	VB
work_ynnlban46ndsvo6vb56iybocpu	45	16	when	when	WRB
work_ynnlban46ndsvo6vb56iybocpu	45	17	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	45	18	drug	drug	NN
work_ynnlban46ndsvo6vb56iybocpu	45	19	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	45	20	applied	apply	VBN
work_ynnlban46ndsvo6vb56iybocpu	45	21	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	45	22	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	45	23	conducting	conduct	VBG
work_ynnlban46ndsvo6vb56iybocpu	45	24	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	45	25	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	45	26	but	but	CC
work_ynnlban46ndsvo6vb56iybocpu	45	27	no	no	DT
work_ynnlban46ndsvo6vb56iybocpu	45	28	trapping	trapping	NN
work_ynnlban46ndsvo6vb56iybocpu	45	29	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	45	30	C10	C10	NNP
work_ynnlban46ndsvo6vb56iybocpu	45	31	will	will	MD
work_ynnlban46ndsvo6vb56iybocpu	45	32	be	be	VB
work_ynnlban46ndsvo6vb56iybocpu	45	33	observed	observe	VBN
work_ynnlban46ndsvo6vb56iybocpu	45	34	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	45	35	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	45	36	closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	45	37	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	45	38	inactivated	inactivated	JJ
work_ynnlban46ndsvo6vb56iybocpu	45	39	states	state	NNS
work_ynnlban46ndsvo6vb56iybocpu	45	40	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	46	1	Supported	support	VBN
work_ynnlban46ndsvo6vb56iybocpu	46	2	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	46	3	NIH	NIH	NNP
work_ynnlban46ndsvo6vb56iybocpu	46	4	grant	grant	NN
work_ynnlban46ndsvo6vb56iybocpu	46	5	R01	R01	NNP
work_ynnlban46ndsvo6vb56iybocpu	46	6	NS032337	NS032337	NNP
work_ynnlban46ndsvo6vb56iybocpu	46	7	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	46	8	MC	MC	NNP
work_ynnlban46ndsvo6vb56iybocpu	46	9	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	46	10	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	47	1	653-Pos	653-Pos	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	2	Board	Board	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	3	B422	B422	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	4	Water	Water	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	5	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	47	6	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	47	7	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	8	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	9	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	10	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	47	11	Quantum	Quantum	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	12	Calculations	Calculations	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	13	Show	show	VBP
work_ynnlban46ndsvo6vb56iybocpu	47	14	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	47	15	Oscillation	Oscillation	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	16	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	47	17	Water	Water	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	18	Structure	Structure	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	19	Alisher	Alisher	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	20	M.	M.	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	21	Kariev	Kariev	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	22	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	47	23	Michael	Michael	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	24	E.	E.	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	25	Green	Green	NNP
work_ynnlban46ndsvo6vb56iybocpu	47	26	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	48	1	City	City	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	2	College	College	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	3	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	48	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	48	5	City	City	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	6	University	University	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	7	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	48	8	NY	NY	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	9	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	48	10	New	New	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	11	York	York	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	48	13	NY	NY	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	14	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	48	15	USA	USA	NNP
work_ynnlban46ndsvo6vb56iybocpu	48	16	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	49	1	Quantum	Quantum	NNP
work_ynnlban46ndsvo6vb56iybocpu	49	2	calculations	calculation	NNS
work_ynnlban46ndsvo6vb56iybocpu	49	3	on	on	IN
work_ynnlban46ndsvo6vb56iybocpu	49	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	49	5	open	open	JJ
work_ynnlban46ndsvo6vb56iybocpu	49	6	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	49	7	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	49	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	49	9	immediately	immediately	RB
work_ynnlban46ndsvo6vb56iybocpu	49	10	surrounding	surround	VBG
work_ynnlban46ndsvo6vb56iybocpu	49	11	re-	re-	JJ
work_ynnlban46ndsvo6vb56iybocpu	49	12	gion	gion	NN
work_ynnlban46ndsvo6vb56iybocpu	49	13	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	49	14	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	49	15	Kv1.2	Kv1.2	NNP
work_ynnlban46ndsvo6vb56iybocpu	49	16	voltage	voltage	NN
work_ynnlban46ndsvo6vb56iybocpu	49	17	gated	gated	NNP
work_ynnlban46ndsvo6vb56iybocpu	49	18	potassium	potassium	NN
work_ynnlban46ndsvo6vb56iybocpu	49	19	channel	channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	49	20	show	show	VBP
work_ynnlban46ndsvo6vb56iybocpu	49	21	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	49	22	water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	49	23	adopts	adopt	VBZ
work_ynnlban46ndsvo6vb56iybocpu	49	24	two	two	CD
work_ynnlban46ndsvo6vb56iybocpu	49	25	conformations	conformation	NNS
work_ynnlban46ndsvo6vb56iybocpu	49	26	there	there	RB
work_ynnlban46ndsvo6vb56iybocpu	49	27	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	49	28	one	one	CD
work_ynnlban46ndsvo6vb56iybocpu	49	29	when	when	WRB
work_ynnlban46ndsvo6vb56iybocpu	49	30	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	49	31	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	49	32	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	49	33	present	present	JJ
work_ynnlban46ndsvo6vb56iybocpu	49	34	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	49	35	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	49	36	another	another	DT
work_ynnlban46ndsvo6vb56iybocpu	49	37	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	49	38	no	no	DT
work_ynnlban46ndsvo6vb56iybocpu	49	39	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	49	40	present	present	NN
work_ynnlban46ndsvo6vb56iybocpu	49	41	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	50	1	An	an	DT
work_ynnlban46ndsvo6vb56iybocpu	50	2	energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	50	3	minimum	minimum	NN
work_ynnlban46ndsvo6vb56iybocpu	50	4	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	50	5	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	6	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	50	7	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	50	8	no	no	DT
work_ynnlban46ndsvo6vb56iybocpu	50	9	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	50	10	allows	allow	VBZ
work_ynnlban46ndsvo6vb56iybocpu	50	11	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	50	12	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	50	13	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	50	14	enter	enter	VB
work_ynnlban46ndsvo6vb56iybocpu	50	15	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	50	16	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	17	solution	solution	NN
work_ynnlban46ndsvo6vb56iybocpu	50	18	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	50	19	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	50	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	21	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	50	22	it	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	50	23	repels	repel	VBZ
work_ynnlban46ndsvo6vb56iybocpu	50	24	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	50	25	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	50	26	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	50	27	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	28	channel	channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	50	29	pore	pore	NNP
work_ynnlban46ndsvo6vb56iybocpu	50	30	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	50	31	into	into	IN
work_ynnlban46ndsvo6vb56iybocpu	50	32	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	33	selectivity	selectivity	NN
work_ynnlban46ndsvo6vb56iybocpu	50	34	filter	filter	NN
work_ynnlban46ndsvo6vb56iybocpu	50	35	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	50	36	essentially	essentially	RB
work_ynnlban46ndsvo6vb56iybocpu	50	37	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	50	38	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	50	39	‘	'	``
work_ynnlban46ndsvo6vb56iybocpu	50	40	knock	knock	VB
work_ynnlban46ndsvo6vb56iybocpu	50	41	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	50	42	on	on	RP
work_ynnlban46ndsvo6vb56iybocpu	50	43	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	50	44	’	'	''
work_ynnlban46ndsvo6vb56iybocpu	50	45	mechanism	mechanism	NN
work_ynnlban46ndsvo6vb56iybocpu	50	46	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	50	47	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	51	1	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	51	2	pore	pore	NN
work_ynnlban46ndsvo6vb56iybocpu	51	3	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	51	4	minimum	minimum	NN
work_ynnlban46ndsvo6vb56iybocpu	51	5	can	can	MD
work_ynnlban46ndsvo6vb56iybocpu	51	6	then	then	RB
work_ynnlban46ndsvo6vb56iybocpu	51	7	be	be	VB
work_ynnlban46ndsvo6vb56iybocpu	51	8	occupied	occupy	VBN
work_ynnlban46ndsvo6vb56iybocpu	51	9	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	51	10	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	51	11	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	51	12	moving	move	VBG
work_ynnlban46ndsvo6vb56iybocpu	51	13	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	51	14	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	51	15	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	51	16	minimum	minimum	NN
work_ynnlban46ndsvo6vb56iybocpu	51	17	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	51	18	leaving	leave	VBG
work_ynnlban46ndsvo6vb56iybocpu	51	19	it	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	51	20	available	available	JJ
work_ynnlban46ndsvo6vb56iybocpu	51	21	for	for	IN
work_ynnlban46ndsvo6vb56iybocpu	51	22	anion	anion	NN
work_ynnlban46ndsvo6vb56iybocpu	51	23	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	51	24	bulk	bulk	NN
work_ynnlban46ndsvo6vb56iybocpu	51	25	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	51	26	so	so	RB
work_ynnlban46ndsvo6vb56iybocpu	51	27	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	51	28	cycle	cycle	NN
work_ynnlban46ndsvo6vb56iybocpu	51	29	continues	continue	VBZ
work_ynnlban46ndsvo6vb56iybocpu	51	30	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	52	1	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	2	arrange-	arrange-	JJ
work_ynnlban46ndsvo6vb56iybocpu	52	3	ment	ment	NN
work_ynnlban46ndsvo6vb56iybocpu	52	4	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	52	5	water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	52	6	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	52	7	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	52	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	9	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	52	10	hydration	hydration	NN
work_ynnlban46ndsvo6vb56iybocpu	52	11	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	52	12	defines	define	VBZ
work_ynnlban46ndsvo6vb56iybocpu	52	13	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	14	gate	gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	52	15	energy	energy	NNP
work_ynnlban46ndsvo6vb56iybocpu	52	16	minimum	minimum	NNP
work_ynnlban46ndsvo6vb56iybocpu	52	17	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	52	18	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	52	19	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	52	20	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	52	21	turn	turn	NN
work_ynnlban46ndsvo6vb56iybocpu	52	22	depends	depend	VBZ
work_ynnlban46ndsvo6vb56iybocpu	52	23	on	on	IN
work_ynnlban46ndsvo6vb56iybocpu	52	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	25	highly	highly	RB
work_ynnlban46ndsvo6vb56iybocpu	52	26	conserved	conserve	VBN
work_ynnlban46ndsvo6vb56iybocpu	52	27	prolines	proline	NNS
work_ynnlban46ndsvo6vb56iybocpu	52	28	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	52	29	especially	especially	RB
work_ynnlban46ndsvo6vb56iybocpu	52	30	P407	P407	NNP
work_ynnlban46ndsvo6vb56iybocpu	52	31	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	52	32	2A79	2a79	CD
work_ynnlban46ndsvo6vb56iybocpu	52	33	pdb	pdb	NN
work_ynnlban46ndsvo6vb56iybocpu	52	34	numbering	numbering	NN
work_ynnlban46ndsvo6vb56iybocpu	52	35	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	52	36	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	52	37	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	52	38	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	39	PVPV	PVPV	NNP
work_ynnlban46ndsvo6vb56iybocpu	52	40	sequence	sequence	NN
work_ynnlban46ndsvo6vb56iybocpu	52	41	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	52	42	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	52	43	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	52	44	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	53	1	Absent	absent	VB
work_ynnlban46ndsvo6vb56iybocpu	53	2	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	53	3	energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	53	4	minimum	minimum	NN
work_ynnlban46ndsvo6vb56iybocpu	53	5	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	53	6	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	53	7	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	53	8	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	53	9	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	53	10	entering	enter	VBG
work_ynnlban46ndsvo6vb56iybocpu	53	11	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	53	12	solution	solution	NN
work_ynnlban46ndsvo6vb56iybocpu	53	13	would	would	MD
work_ynnlban46ndsvo6vb56iybocpu	53	14	be	be	VB
work_ynnlban46ndsvo6vb56iybocpu	53	15	repelled	repel	VBN
work_ynnlban46ndsvo6vb56iybocpu	53	16	back	back	RB
work_ynnlban46ndsvo6vb56iybocpu	53	17	into	into	IN
work_ynnlban46ndsvo6vb56iybocpu	53	18	solution	solution	NN
work_ynnlban46ndsvo6vb56iybocpu	53	19	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	53	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	53	21	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	53	22	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	53	23	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	53	24	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	53	25	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	54	1	Furthermore	furthermore	RB
work_ynnlban46ndsvo6vb56iybocpu	54	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	54	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	54	4	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	54	5	remains	remain	VBZ
work_ynnlban46ndsvo6vb56iybocpu	54	6	hydrated	hydrate	VBN
work_ynnlban46ndsvo6vb56iybocpu	54	7	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	54	8	8	8	CD
work_ynnlban46ndsvo6vb56iybocpu	54	9	water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	54	10	molecules	molecule	NNS
work_ynnlban46ndsvo6vb56iybocpu	54	11	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	54	12	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	54	13	least	least	JJS
work_ynnlban46ndsvo6vb56iybocpu	54	14	1	1	CD
work_ynnlban46ndsvo6vb56iybocpu	54	15	more	more	JJR
work_ynnlban46ndsvo6vb56iybocpu	54	16	than	than	IN
work_ynnlban46ndsvo6vb56iybocpu	54	17	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	54	18	bulk	bulk	NN
work_ynnlban46ndsvo6vb56iybocpu	54	19	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	54	20	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	54	21	it	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	54	22	passes	pass	VBZ
work_ynnlban46ndsvo6vb56iybocpu	54	23	through	through	IN
work_ynnlban46ndsvo6vb56iybocpu	54	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	54	25	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	54	26	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	54	27	based	base	VBN
work_ynnlban46ndsvo6vb56iybocpu	54	28	on	on	IN
work_ynnlban46ndsvo6vb56iybocpu	54	29	optimizations	optimization	NNS
work_ynnlban46ndsvo6vb56iybocpu	54	30	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	54	31	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	54	32	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	54	33	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	54	34	three	three	CD
work_ynnlban46ndsvo6vb56iybocpu	54	35	different	different	JJ
work_ynnlban46ndsvo6vb56iybocpu	54	36	positions	position	NNS
work_ynnlban46ndsvo6vb56iybocpu	54	37	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	54	38	1	1	LS
work_ynnlban46ndsvo6vb56iybocpu	54	39	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	54	40	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	54	41	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	54	42	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	54	43	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	54	44	nearest	nearest	NNP
work_ynnlban46ndsvo6vb56iybocpu	54	45	P407	P407	NNP
work_ynnlban46ndsvo6vb56iybocpu	54	46	2	2	CD
work_ynnlban46ndsvo6vb56iybocpu	54	47	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	54	48	2Å	2å	CD
work_ynnlban46ndsvo6vb56iybocpu	54	49	above	above	IN
work_ynnlban46ndsvo6vb56iybocpu	54	50	3	3	CD
work_ynnlban46ndsvo6vb56iybocpu	54	51	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	54	52	2Å	2å	CD
work_ynnlban46ndsvo6vb56iybocpu	54	53	below	below	IN
work_ynnlban46ndsvo6vb56iybocpu	54	54	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	54	55	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	54	56	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	54	57	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	55	1	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	55	2	open	open	JJ
work_ynnlban46ndsvo6vb56iybocpu	55	3	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	55	4	maintains	maintain	VBZ
work_ynnlban46ndsvo6vb56iybocpu	55	5	very	very	RB
work_ynnlban46ndsvo6vb56iybocpu	55	6	nearly	nearly	RB
work_ynnlban46ndsvo6vb56iybocpu	55	7	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	55	8	same	same	JJ
work_ynnlban46ndsvo6vb56iybocpu	55	9	protein	protein	NN
work_ynnlban46ndsvo6vb56iybocpu	55	10	atom	atom	NN
work_ynnlban46ndsvo6vb56iybocpu	55	11	positions	position	NNS
work_ynnlban46ndsvo6vb56iybocpu	55	12	throughout	throughout	IN
work_ynnlban46ndsvo6vb56iybocpu	55	13	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	56	1	Additional	additional	JJ
work_ynnlban46ndsvo6vb56iybocpu	56	2	calculations	calculation	NNS
work_ynnlban46ndsvo6vb56iybocpu	56	3	will	will	MD
work_ynnlban46ndsvo6vb56iybocpu	56	4	be	be	VB
work_ynnlban46ndsvo6vb56iybocpu	56	5	required	require	VBN
work_ynnlban46ndsvo6vb56iybocpu	56	6	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	56	7	determine	determine	VB
work_ynnlban46ndsvo6vb56iybocpu	56	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	56	9	exact	exact	NNP
work_ynnlban46ndsvo6vb56iybocpu	56	10	interaction	interaction	NN
work_ynnlban46ndsvo6vb56iybocpu	56	11	en-	en-	CC
work_ynnlban46ndsvo6vb56iybocpu	56	12	ergy	ergy	NN
work_ynnlban46ndsvo6vb56iybocpu	56	13	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	56	14	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	56	15	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	56	16	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	56	17	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	56	18	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	56	19	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	56	20	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	56	21	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	56	22	amount	amount	NN
work_ynnlban46ndsvo6vb56iybocpu	56	23	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	56	24	water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	56	25	that	that	WDT
work_ynnlban46ndsvo6vb56iybocpu	56	26	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	56	27	present	present	JJ
work_ynnlban46ndsvo6vb56iybocpu	56	28	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	56	29	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	56	30	cavity	cavity	NN
work_ynnlban46ndsvo6vb56iybocpu	56	31	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	57	1	Optimizations	optimization	NNS
work_ynnlban46ndsvo6vb56iybocpu	57	2	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	57	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	57	4	system	system	NN
work_ynnlban46ndsvo6vb56iybocpu	57	5	configuration	configuration	NN
work_ynnlban46ndsvo6vb56iybocpu	57	6	were	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	57	7	done	do	VBN
work_ynnlban46ndsvo6vb56iybocpu	57	8	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	57	9	HF/4	HF/4	NNP
work_ynnlban46ndsvo6vb56iybocpu	57	10	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	57	11	22GSP	22gsp	CD
work_ynnlban46ndsvo6vb56iybocpu	57	12	level	level	NN
work_ynnlban46ndsvo6vb56iybocpu	57	13	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	57	14	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	57	15	692	692	CD
work_ynnlban46ndsvo6vb56iybocpu	57	16	atoms	atom	NNS
work_ynnlban46ndsvo6vb56iybocpu	57	17	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	57	18	693	693	CD
work_ynnlban46ndsvo6vb56iybocpu	57	19	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	57	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	57	21	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	57	22	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	57	23	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	58	1	Energy	energy	NN
work_ynnlban46ndsvo6vb56iybocpu	58	2	was	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	58	3	determined	determine	VBN
work_ynnlban46ndsvo6vb56iybocpu	58	4	using	use	VBG
work_ynnlban46ndsvo6vb56iybocpu	58	5	both	both	DT
work_ynnlban46ndsvo6vb56iybocpu	58	6	B3LYP/6	B3LYP/6	NNP
work_ynnlban46ndsvo6vb56iybocpu	58	7	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	58	8	31	31	CD
work_ynnlban46ndsvo6vb56iybocpu	58	9	G	g	NN
work_ynnlban46ndsvo6vb56iybocpu	58	10	*	*	NFP
work_ynnlban46ndsvo6vb56iybocpu	58	11	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	58	12	bvp86/6	bvp86/6	NN
work_ynnlban46ndsvo6vb56iybocpu	58	13	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	58	14	31	31	CD
work_ynnlban46ndsvo6vb56iybocpu	58	15	G	g	NN
work_ynnlban46ndsvo6vb56iybocpu	58	16	*	*	NFP
work_ynnlban46ndsvo6vb56iybocpu	58	17	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	58	18	but	but	CC
work_ynnlban46ndsvo6vb56iybocpu	58	19	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	58	20	system	system	NN
work_ynnlban46ndsvo6vb56iybocpu	58	21	was	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	58	22	too	too	RB
work_ynnlban46ndsvo6vb56iybocpu	58	23	large	large	JJ
work_ynnlban46ndsvo6vb56iybocpu	58	24	for	for	IN
work_ynnlban46ndsvo6vb56iybocpu	58	25	free	free	JJ
work_ynnlban46ndsvo6vb56iybocpu	58	26	en-	en-	NN
work_ynnlban46ndsvo6vb56iybocpu	58	27	ergy	ergy	NN
work_ynnlban46ndsvo6vb56iybocpu	58	28	determination	determination	NN
work_ynnlban46ndsvo6vb56iybocpu	58	29	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	59	1	654-Pos	654-Pos	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	2	Board	Board	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	3	B423	B423	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	4	Water	Water	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	5	Structure	Structure	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	6	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	59	7	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	59	8	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	9	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	10	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	11	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	59	12	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	59	13	Importance	importance	NN
work_ynnlban46ndsvo6vb56iybocpu	59	14	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	59	15	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	59	16	Prolines	Prolines	NNPS
work_ynnlban46ndsvo6vb56iybocpu	59	17	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	59	18	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	59	19	PVPV	PVPV	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	20	Sequence	Sequence	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	21	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	59	22	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	59	23	Shown	show	VBN
work_ynnlban46ndsvo6vb56iybocpu	59	24	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	59	25	Computational	Computational	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	26	Mutations	Mutations	NNPS
work_ynnlban46ndsvo6vb56iybocpu	59	27	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	59	28	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	59	29	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	59	30	Role	role	NN
work_ynnlban46ndsvo6vb56iybocpu	59	31	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	59	32	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	59	33	Histidine	Histidine	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	34	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	59	35	Gating	Gating	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	36	Alisher	Alisher	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	37	M.	M.	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	38	Kariev	Kariev	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	39	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	59	40	Michael	Michael	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	41	E.	E.	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	42	Green	Green	NNP
work_ynnlban46ndsvo6vb56iybocpu	59	43	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	60	1	City	City	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	2	College	College	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	3	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	60	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	60	5	City	City	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	6	University	University	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	7	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	60	8	NY	NY	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	9	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	60	10	New	New	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	11	York	York	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	12	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	60	13	NY	NY	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	14	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	60	15	USA	USA	NNP
work_ynnlban46ndsvo6vb56iybocpu	60	16	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	61	1	Conservation	conservation	NN
work_ynnlban46ndsvo6vb56iybocpu	61	2	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	61	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	61	4	PVPV	PVPV	NNP
work_ynnlban46ndsvo6vb56iybocpu	61	5	sequence	sequence	NN
work_ynnlban46ndsvo6vb56iybocpu	61	6	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	61	7	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	61	8	potassium	potassium	NN
work_ynnlban46ndsvo6vb56iybocpu	61	9	channel	channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	61	10	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	61	11	has	have	VBZ
work_ynnlban46ndsvo6vb56iybocpu	61	12	not	not	RB
work_ynnlban46ndsvo6vb56iybocpu	61	13	been	be	VBN
work_ynnlban46ndsvo6vb56iybocpu	61	14	well	well	RB
work_ynnlban46ndsvo6vb56iybocpu	61	15	understood	understand	VBN
work_ynnlban46ndsvo6vb56iybocpu	61	16	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	62	1	Quantum	Quantum	NNP
work_ynnlban46ndsvo6vb56iybocpu	62	2	computations	computation	NNS
work_ynnlban46ndsvo6vb56iybocpu	62	3	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	62	4	optimization	optimization	NN
work_ynnlban46ndsvo6vb56iybocpu	62	5	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	62	6	HF/4	HF/4	NNP
work_ynnlban46ndsvo6vb56iybocpu	62	7	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	62	8	22GSP	22gsp	CD
work_ynnlban46ndsvo6vb56iybocpu	62	9	level	level	NN
work_ynnlban46ndsvo6vb56iybocpu	62	10	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	62	11	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	62	12	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	62	13	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	62	14	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	62	15	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	62	16	Kv1.2	Kv1.2	NNP
work_ynnlban46ndsvo6vb56iybocpu	62	17	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	62	18	that	that	WDT
work_ynnlban46ndsvo6vb56iybocpu	62	19	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	62	20	presented	present	VBN
work_ynnlban46ndsvo6vb56iybocpu	62	21	here	here	RB
work_ynnlban46ndsvo6vb56iybocpu	62	22	show	show	VBP
work_ynnlban46ndsvo6vb56iybocpu	62	23	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	62	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	62	25	proline	proline	JJ
work_ynnlban46ndsvo6vb56iybocpu	62	26	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	62	27	proline	proline	NN
work_ynnlban46ndsvo6vb56iybocpu	62	28	distances	distance	NNS
work_ynnlban46ndsvo6vb56iybocpu	62	29	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	62	30	ring	ring	NN
work_ynnlban46ndsvo6vb56iybocpu	62	31	atoms	atom	NNS
work_ynnlban46ndsvo6vb56iybocpu	62	32	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	62	33	are	be	VBP
work_ynnlban46ndsvo6vb56iybocpu	62	34	preserved	preserve	VBN
work_ynnlban46ndsvo6vb56iybocpu	62	35	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	62	36	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	62	37	ion	ion	NN
work_ynnlban46ndsvo6vb56iybocpu	62	38	moves	move	VBZ
work_ynnlban46ndsvo6vb56iybocpu	62	39	through	through	IN
work_ynnlban46ndsvo6vb56iybocpu	62	40	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	62	41	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	62	42	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	63	1	This	this	DT
work_ynnlban46ndsvo6vb56iybocpu	63	2	calculation	calculation	NN
work_ynnlban46ndsvo6vb56iybocpu	63	3	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	63	4	supplemented	supplement	VBN
work_ynnlban46ndsvo6vb56iybocpu	63	5	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	63	6	mutating	mutate	VBG
work_ynnlban46ndsvo6vb56iybocpu	63	7	one	one	CD
work_ynnlban46ndsvo6vb56iybocpu	63	8	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	63	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	63	10	prolines	proline	NNS
work_ynnlban46ndsvo6vb56iybocpu	63	11	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	63	12	valine	valine	NN
work_ynnlban46ndsvo6vb56iybocpu	63	13	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	63	14	P407V	p407v	CD
work_ynnlban46ndsvo6vb56iybocpu	63	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	63	16	2A79	2a79	CD
work_ynnlban46ndsvo6vb56iybocpu	63	17	pdb	pdb	NN
work_ynnlban46ndsvo6vb56iybocpu	63	18	numbering	numbering	NN
work_ynnlban46ndsvo6vb56iybocpu	63	19	for	for	IN
work_ynnlban46ndsvo6vb56iybocpu	63	20	all	all	DT
work_ynnlban46ndsvo6vb56iybocpu	63	21	residues	residue	NNS
work_ynnlban46ndsvo6vb56iybocpu	63	22	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	63	23	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	63	24	abstract	abstract	NN
work_ynnlban46ndsvo6vb56iybocpu	63	25	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	63	26	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	63	27	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	63	28	computation	computation	NN
work_ynnlban46ndsvo6vb56iybocpu	63	29	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	63	30	producing	produce	VBG
work_ynnlban46ndsvo6vb56iybocpu	63	31	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	63	32	PVVV	pvvv	NN
work_ynnlban46ndsvo6vb56iybocpu	63	33	sequence	sequence	NN
work_ynnlban46ndsvo6vb56iybocpu	63	34	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	64	1	Water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	64	2	structure	structure	NN
work_ynnlban46ndsvo6vb56iybocpu	64	3	changed	change	VBN
work_ynnlban46ndsvo6vb56iybocpu	64	4	dramati-	dramati-	NN
work_ynnlban46ndsvo6vb56iybocpu	64	5	cally	cally	RB
work_ynnlban46ndsvo6vb56iybocpu	64	6	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	64	7	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	64	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	64	9	protein	protein	NN
work_ynnlban46ndsvo6vb56iybocpu	64	10	backbone	backbone	NN
work_ynnlban46ndsvo6vb56iybocpu	64	11	moved	move	VBD
work_ynnlban46ndsvo6vb56iybocpu	64	12	inward	inward	RB
work_ynnlban46ndsvo6vb56iybocpu	64	13	nearly	nearly	RB
work_ynnlban46ndsvo6vb56iybocpu	64	14	3Å	3å	CD
work_ynnlban46ndsvo6vb56iybocpu	64	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	64	16	effectively	effectively	RB
work_ynnlban46ndsvo6vb56iybocpu	64	17	closing	close	VBG
work_ynnlban46ndsvo6vb56iybocpu	64	18	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	64	19	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	64	20	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	64	21	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	64	22	proline	proline	NN
work_ynnlban46ndsvo6vb56iybocpu	64	23	ring	re	VBG
work_ynnlban46ndsvo6vb56iybocpu	64	24	N	N	NNP
work_ynnlban46ndsvo6vb56iybocpu	64	25	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	64	26	N	n	CD
work_ynnlban46ndsvo6vb56iybocpu	64	27	distance	distance	NN
work_ynnlban46ndsvo6vb56iybocpu	64	28	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	64	29	diagonally	diagonally	RB
work_ynnlban46ndsvo6vb56iybocpu	64	30	opposite	opposite	JJ
work_ynnlban46ndsvo6vb56iybocpu	64	31	pro-	pro-	NN
work_ynnlban46ndsvo6vb56iybocpu	64	32	lines	line	NNS
work_ynnlban46ndsvo6vb56iybocpu	64	33	dropped	drop	VBD
work_ynnlban46ndsvo6vb56iybocpu	64	34	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	64	35	14.3	14.3	CD
work_ynnlban46ndsvo6vb56iybocpu	64	36	Å	Å	NNS
work_ynnlban46ndsvo6vb56iybocpu	64	37	(	(	-LRB-
work_ynnlban46ndsvo6vb56iybocpu	64	38	distance	distance	NN
work_ynnlban46ndsvo6vb56iybocpu	64	39	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	64	40	optimization	optimization	NN
work_ynnlban46ndsvo6vb56iybocpu	64	41	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	64	42	X	x	NN
work_ynnlban46ndsvo6vb56iybocpu	64	43	-	-	NN
work_ynnlban46ndsvo6vb56iybocpu	64	44	ray	ray	NN
work_ynnlban46ndsvo6vb56iybocpu	64	45	distance	distance	NN
work_ynnlban46ndsvo6vb56iybocpu	64	46	=	=	SYM
work_ynnlban46ndsvo6vb56iybocpu	64	47	15.6Å	15.6å	CD
work_ynnlban46ndsvo6vb56iybocpu	64	48	)	)	-RRB-
work_ynnlban46ndsvo6vb56iybocpu	64	49	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	64	50	11.4	11.4	CD
work_ynnlban46ndsvo6vb56iybocpu	64	51	Å	Å	NNS
work_ynnlban46ndsvo6vb56iybocpu	64	52	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	64	53	too	too	RB
work_ynnlban46ndsvo6vb56iybocpu	64	54	small	small	JJ
work_ynnlban46ndsvo6vb56iybocpu	64	55	to	to	TO
work_ynnlban46ndsvo6vb56iybocpu	64	56	allow	allow	VB
work_ynnlban46ndsvo6vb56iybocpu	64	57	passage	passage	NN
work_ynnlban46ndsvo6vb56iybocpu	64	58	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	64	59	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	64	60	hydrated	hydrated	JJ
work_ynnlban46ndsvo6vb56iybocpu	64	61	K	k	NN
work_ynnlban46ndsvo6vb56iybocpu	64	62	þ	þ	NN
work_ynnlban46ndsvo6vb56iybocpu	64	63	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	65	1	This	this	DT
work_ynnlban46ndsvo6vb56iybocpu	65	2	suggests	suggest	VBZ
work_ynnlban46ndsvo6vb56iybocpu	65	3	that	that	IN
work_ynnlban46ndsvo6vb56iybocpu	65	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	65	5	prolines	proline	NNS
work_ynnlban46ndsvo6vb56iybocpu	65	6	play	play	VBP
work_ynnlban46ndsvo6vb56iybocpu	65	7	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	65	8	key	key	JJ
work_ynnlban46ndsvo6vb56iybocpu	65	9	structural	structural	JJ
work_ynnlban46ndsvo6vb56iybocpu	65	10	role	role	NN
work_ynnlban46ndsvo6vb56iybocpu	65	11	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	65	12	modulating	modulate	VBG
work_ynnlban46ndsvo6vb56iybocpu	65	13	both	both	CC
work_ynnlban46ndsvo6vb56iybocpu	65	14	protein	protein	NN
work_ynnlban46ndsvo6vb56iybocpu	65	15	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	65	16	water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	65	17	structure	structure	NN
work_ynnlban46ndsvo6vb56iybocpu	65	18	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	66	1	Furthermore	furthermore	RB
work_ynnlban46ndsvo6vb56iybocpu	66	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	66	3	protonation	protonation	NN
work_ynnlban46ndsvo6vb56iybocpu	66	4	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	66	5	H418	H418	NNP
work_ynnlban46ndsvo6vb56iybocpu	66	6	may	may	MD
work_ynnlban46ndsvo6vb56iybocpu	66	7	close	close	VB
work_ynnlban46ndsvo6vb56iybocpu	66	8	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	66	9	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	66	10	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	67	1	Protonation	protonation	NN
work_ynnlban46ndsvo6vb56iybocpu	67	2	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	67	3	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	67	4	histidine	histidine	NN
work_ynnlban46ndsvo6vb56iybocpu	67	5	shows	show	VBZ
work_ynnlban46ndsvo6vb56iybocpu	67	6	it	-PRON-	PRP
work_ynnlban46ndsvo6vb56iybocpu	67	7	moving	move	VBG
work_ynnlban46ndsvo6vb56iybocpu	67	8	toward	toward	IN
work_ynnlban46ndsvo6vb56iybocpu	67	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	67	10	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	67	11	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	67	12	about	about	RB
work_ynnlban46ndsvo6vb56iybocpu	67	13	3	3	CD
work_ynnlban46ndsvo6vb56iybocpu	67	14	Å	Å	NNS
work_ynnlban46ndsvo6vb56iybocpu	67	15	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	67	16	which	which	WDT
work_ynnlban46ndsvo6vb56iybocpu	67	17	should	should	MD
work_ynnlban46ndsvo6vb56iybocpu	67	18	close	close	VB
work_ynnlban46ndsvo6vb56iybocpu	67	19	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	67	20	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	67	21	electrostatically	electrostatically	RB
work_ynnlban46ndsvo6vb56iybocpu	67	22	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	67	23	while	while	IN
work_ynnlban46ndsvo6vb56iybocpu	67	24	deprotonation	deprotonation	NN
work_ynnlban46ndsvo6vb56iybocpu	67	25	opens	open	VBZ
work_ynnlban46ndsvo6vb56iybocpu	67	26	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	67	27	gate	gate	NN
work_ynnlban46ndsvo6vb56iybocpu	67	28	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	68	1	Protonation	protonation	NN
work_ynnlban46ndsvo6vb56iybocpu	68	2	was	be	VBD
work_ynnlban46ndsvo6vb56iybocpu	68	3	calculated	calculate	VBN
work_ynnlban46ndsvo6vb56iybocpu	68	4	with	with	IN
work_ynnlban46ndsvo6vb56iybocpu	68	5	two	two	CD
work_ynnlban46ndsvo6vb56iybocpu	68	6	added	add	VBN
work_ynnlban46ndsvo6vb56iybocpu	68	7	protons	proton	NNS
work_ynnlban46ndsvo6vb56iybocpu	68	8	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	68	9	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	68	10	other	other	JJ
work_ynnlban46ndsvo6vb56iybocpu	68	11	being	be	VBG
work_ynnlban46ndsvo6vb56iybocpu	68	12	accepted	accept	VBN
work_ynnlban46ndsvo6vb56iybocpu	68	13	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	68	14	E142	E142	NNP
work_ynnlban46ndsvo6vb56iybocpu	68	15	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	68	16	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	68	17	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	68	18	intracellular	intracellular	JJ
work_ynnlban46ndsvo6vb56iybocpu	68	19	moiety	moiety	NN
work_ynnlban46ndsvo6vb56iybocpu	68	20	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	69	1	When	when	WRB
work_ynnlban46ndsvo6vb56iybocpu	69	2	deprotonated	deprotonate	VBN
work_ynnlban46ndsvo6vb56iybocpu	69	3	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	69	4	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	69	5	histidine	histidine	NN
work_ynnlban46ndsvo6vb56iybocpu	69	6	does	do	VBZ
work_ynnlban46ndsvo6vb56iybocpu	69	7	not	not	RB
work_ynnlban46ndsvo6vb56iybocpu	69	8	move	move	VB
work_ynnlban46ndsvo6vb56iybocpu	69	9	as	as	RB
work_ynnlban46ndsvo6vb56iybocpu	69	10	much	much	JJ
work_ynnlban46ndsvo6vb56iybocpu	69	11	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	69	12	1Å	1å	CD
work_ynnlban46ndsvo6vb56iybocpu	69	13	from	from	IN
work_ynnlban46ndsvo6vb56iybocpu	69	14	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	69	15	X	x	NN
work_ynnlban46ndsvo6vb56iybocpu	69	16	-	-	NN
work_ynnlban46ndsvo6vb56iybocpu	69	17	ray	ray	NN
work_ynnlban46ndsvo6vb56iybocpu	69	18	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	69	19	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	69	20	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	69	21	optimization	optimization	NN
work_ynnlban46ndsvo6vb56iybocpu	69	22	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	69	23	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	69	24	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	69	25	linked	link	VBN
work_ynnlban46ndsvo6vb56iybocpu	69	26	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	69	27	E142	E142	NNP
work_ynnlban46ndsvo6vb56iybocpu	69	28	;	;	:
work_ynnlban46ndsvo6vb56iybocpu	69	29	this	this	DT
work_ynnlban46ndsvo6vb56iybocpu	69	30	accounts	account	VBZ
work_ynnlban46ndsvo6vb56iybocpu	69	31	for	for	IN
work_ynnlban46ndsvo6vb56iybocpu	69	32	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	69	33	known	know	VBN
work_ynnlban46ndsvo6vb56iybocpu	69	34	importance	importance	NN
work_ynnlban46ndsvo6vb56iybocpu	69	35	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	69	36	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	69	37	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	69	38	segment	segment	NN
work_ynnlban46ndsvo6vb56iybocpu	69	39	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	69	40	gating	gate	VBG
work_ynnlban46ndsvo6vb56iybocpu	69	41	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	70	1	E136	E136	NNP
work_ynnlban46ndsvo6vb56iybocpu	70	2	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	70	3	also	also	RB
work_ynnlban46ndsvo6vb56iybocpu	70	4	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	70	5	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	70	6	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	70	7	could	could	MD
work_ynnlban46ndsvo6vb56iybocpu	70	8	accept	accept	VB
work_ynnlban46ndsvo6vb56iybocpu	70	9	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	70	10	third	third	JJ
work_ynnlban46ndsvo6vb56iybocpu	70	11	proton	proton	NNP
work_ynnlban46ndsvo6vb56iybocpu	70	12	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	71	1	There	there	EX
work_ynnlban46ndsvo6vb56iybocpu	71	2	is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	71	3	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	71	4	salt	salt	NN
work_ynnlban46ndsvo6vb56iybocpu	71	5	bridge	bridge	NN
work_ynnlban46ndsvo6vb56iybocpu	71	6	structure	structure	NN
work_ynnlban46ndsvo6vb56iybocpu	71	7	including	include	VBG
work_ynnlban46ndsvo6vb56iybocpu	71	8	these	these	DT
work_ynnlban46ndsvo6vb56iybocpu	71	9	residues	residue	NNS
work_ynnlban46ndsvo6vb56iybocpu	71	10	similar	similar	JJ
work_ynnlban46ndsvo6vb56iybocpu	71	11	to	to	IN
work_ynnlban46ndsvo6vb56iybocpu	71	12	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	71	13	one	one	NN
work_ynnlban46ndsvo6vb56iybocpu	71	14	occupying	occupy	VBG
work_ynnlban46ndsvo6vb56iybocpu	71	15	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	71	16	key	key	JJ
work_ynnlban46ndsvo6vb56iybocpu	71	17	position	position	NN
work_ynnlban46ndsvo6vb56iybocpu	71	18	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	71	19	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	71	20	pro-	pro-	NN
work_ynnlban46ndsvo6vb56iybocpu	71	21	ton	ton	NN
work_ynnlban46ndsvo6vb56iybocpu	71	22	pathway	pathway	NN
work_ynnlban46ndsvo6vb56iybocpu	71	23	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	71	24	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	71	25	Hv1	hv1	JJ
work_ynnlban46ndsvo6vb56iybocpu	71	26	channel	channel	NN
work_ynnlban46ndsvo6vb56iybocpu	71	27	.	.	.
work_ynnlban46ndsvo6vb56iybocpu	72	1	Access	Access	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	2	Constraints	Constraints	NNPS
work_ynnlban46ndsvo6vb56iybocpu	72	3	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	72	4	Binding	Binding	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	5	Energetics	Energetics	NNPS
work_ynnlban46ndsvo6vb56iybocpu	72	6	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	72	7	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	72	8	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	9	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	10	Inactivation	Inactivation	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	11	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	12	Gating	Gating	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	13	Interactions	Interactions	NNPS
work_ynnlban46ndsvo6vb56iybocpu	72	14	between	between	IN
work_ynnlban46ndsvo6vb56iybocpu	72	15	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	72	16	Cytoplasmic	cytoplasmic	JJ
work_ynnlban46ndsvo6vb56iybocpu	72	17	T1	T1	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	18	Domain	Domain	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	19	and	and	CC
work_ynnlban46ndsvo6vb56iybocpu	72	20	Pore	Pore	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	21	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	72	22	a	a	DT
work_ynnlban46ndsvo6vb56iybocpu	72	23	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	24	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	25	Is	be	VBZ
work_ynnlban46ndsvo6vb56iybocpu	72	26	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	72	27	Activation	Activation	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	28	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	29	Closed	close	VBN
work_ynnlban46ndsvo6vb56iybocpu	72	30	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	72	31	Kv	Kv	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	32	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	33	Closed	Closed	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	34	-	-	HYPH
work_ynnlban46ndsvo6vb56iybocpu	72	35	State	state	NN
work_ynnlban46ndsvo6vb56iybocpu	72	36	Inactivation	Inactivation	NNP
work_ynnlban46ndsvo6vb56iybocpu	72	37	?	?	.
work_ynnlban46ndsvo6vb56iybocpu	73	1	Water	water	NN
work_ynnlban46ndsvo6vb56iybocpu	73	2	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	73	3	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	73	4	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	5	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	6	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	7	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	73	8	Quantum	Quantum	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	9	Calculations	Calculations	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	10	Show	show	VBP
work_ynnlban46ndsvo6vb56iybocpu	73	11	an	an	DT
work_ynnlban46ndsvo6vb56iybocpu	73	12	Oscillation	Oscillation	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	13	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	73	14	Water	Water	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	15	Structure	Structure	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	16	Water	Water	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	17	Structure	Structure	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	18	at	at	IN
work_ynnlban46ndsvo6vb56iybocpu	73	19	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	73	20	Potassium	Potassium	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	21	Channel	Channel	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	22	Gate	Gate	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	23	:	:	:
work_ynnlban46ndsvo6vb56iybocpu	73	24	The	the	DT
work_ynnlban46ndsvo6vb56iybocpu	73	25	Importance	importance	NN
work_ynnlban46ndsvo6vb56iybocpu	73	26	of	of	IN
work_ynnlban46ndsvo6vb56iybocpu	73	27	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	73	28	Prolines	Prolines	NNPS
work_ynnlban46ndsvo6vb56iybocpu	73	29	in	in	IN
work_ynnlban46ndsvo6vb56iybocpu	73	30	the	the	DT
work_ynnlban46ndsvo6vb56iybocpu	73	31	PVPV	PVPV	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	32	Sequence	Sequence	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	33	,	,	,
work_ynnlban46ndsvo6vb56iybocpu	73	34	as	as	IN
work_ynnlban46ndsvo6vb56iybocpu	73	35	Shown	show	VBN
work_ynnlban46ndsvo6vb56iybocpu	73	36	by	by	IN
work_ynnlban46ndsvo6vb56iybocpu	73	37	Computation	Computation	NNP
work_ynnlban46ndsvo6vb56iybocpu	73	38	...	...	.