id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
3484zg66p0s	Brandon Edward Haines	Computational Studies on the Mechanism of HMG-CoA Reductase and the Grignard SRN1 Reaction	2014		.txt	text/plain	377	15	37	The enzyme is of considerable biomedical relevance because of the public health impact of its inhibitors called statins that are prescribed to control cholesterol levels and reduce the risks associated with coronary heart disease. The reaction involves a single electron transfer and was originally classified as a nucleophilic radical substitution (SRN1) reaction until radical clock experiments suggested that there is no radical intermediate.	cache/3484zg66p0s.txt	txt/3484zg66p0s.txt