id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
6q182j65f3d	Nur Mustafaoglu	Design of Antibody-Based Diagnostics and Affinity Chromatography Systems Utilizing the Nucleotide Binding Site (NBS)	1904		.txt	text/plain	386	10	8	An underutilized, highly conserved binding domain located on the antibody variable fragment, known as the nucleotide binding site (NBS) was implemented for site-specific functionalization of antibodies and antibody Fab fragments, as well as developing antibody purification systems. A unique small molecule antibody purification was developed by targeting the antibody NBS with surface immobilized NBS analog, and a stable covalent bond between the antibody NBS and the NBS analog was formed through a photo-chemical reaction utilizing UV energy to homogenous site-specific conjugation of target molecules to the light chains of antibodies and antibody Fab fragments.	cache/6q182j65f3d.txt	txt/6q182j65f3d.txt