id author title date pages extension mime words sentence flesch summary cache txt gf06g160j1k Kara Leigh Huegel The Cellular, Molecular, and Developmental Impact of Mutations in NPC1 2011 .txt text/plain 346 18 37 Small molecule inhibitors were utilized to increase the tubulation of NPC1 mutant membranes and improve cholesterol trafficking, indicating the mutant protein is not functionally dead. Proteins identified as absent from NPC1 mutant membranes include cytoplasmic dynein, dynactin, and STARD9, indicating a loss of microtubule based motility. cache/gf06g160j1k.txt txt/gf06g160j1k.txt