id author title date pages extension mime words sentence flesch summary cache txt gx41mg76z0x Peter Ryan McHenry Elucidating the mechanism of action of the novel marine macrolide iejimalide 2008 .txt text/plain 255 9 43 Iejimalides are a novel family of marine macrolides shown to be active against cancer cells in vitro that inhibit vacuolar H+-ATPase (V-ATPase) activity in osteoclast cells. At least one target of ATM/ATR phosphorylation is de-phosphorylated in PC-3 prostate cancer cells in the presence of Iej B, suggesting a block in cell cycle progression at the intra-S-phase checkpoint. cache/gx41mg76z0x.txt txt/gx41mg76z0x.txt