id author title date pages extension mime words sentence flesch summary cache txt h415p843g3v Jianfeng Zhu Application of discontinuous Galerkin finite element methods for vertebrate limb pattern formation 2010 .txt text/plain 208 5 -2 Major outstanding questions regarding vertebrate limb development are how the numbers of skeletal elements along the proximodistal (P-D) and anteroposterior (A-P) axes are determined and how the shape of a growing limb affects skeletalelement formation. A mechanism based on local autoregulation of a molecular activator of cell aggregation coupled to a laterally acting inhibitor (a LALI system), is consistent with in vivo and in vitro experimental results and provides qualitative interpretations of several genetic anomalies affecting limb development. cache/h415p843g3v.txt txt/h415p843g3v.txt