id author title date pages extension mime words sentence flesch summary cache txt hq37vm4346c Sarah Elizabeth Mordan-McCombs Role of the Vitamin D Receptor During Prostate Tumor Progression in the LPB-Tag Mouse Model of Prostate Cancer 2010 .txt text/plain 335 10 27 To investigate the therapeutic potential of vitamin D3 for prostate cancer, we have utilized the LPB-Tag transgenic model of prostate cancer and a vitamin D receptor-null (VDRKO) mouse model to determine the effects of high dietary calcium on tumor progression, and the role of the vitamin D receptor (VDR) in prostate tumor progression. VDRKO tumors show increased epithelial proliferation, resulting in a larger epithelial compartment. cache/hq37vm4346c.txt txt/hq37vm4346c.txt