id author title date pages extension mime words sentence flesch summary cache txt kw52j67591c Anna Louise Heckmann Targeting the Dengue Genome with a Hepatitis Delta Virus Ribozyme 2010 .txt text/plain 254 11 52 Our analyses provide validation of this ribozyme as a candidate effector gene for Dengue virus refractivity in mosquito cells, although future work is necessary to determine the extent of target cleavage. The ability of the ribozyme to cleave this conserved sequence was examined in cell culture using a 5' DENV/firefly luciferase fusion target and luciferase assays, RT-PCR, western dot-blot, and in-vitro cleavage assays. cache/kw52j67591c.txt txt/kw52j67591c.txt