id author title date pages extension mime words sentence flesch summary cache txt r781wd40p83 Amanda E Yamasaki Advancing Our Understanding of Normal and Disease-State Hematopoiesis: Leveraging the Unique Advantages of Induced Pluripotent Stem Cells for Therapeutic Development and Disease Modeling 2021 .txt text/plain 370 8 6 In short, these studies have identified novel miRNA-modulated regulatory pathways enriched in genes differentially-expressed between functional human HSCs and their genetically-matched iPSC-derived counterparts, providing previously unreported insights into recapitulating normal hematopoietic development in vitro. Although a comparatively recent discovery, induced pluripotent stem cells (iPSCs) have enabled astonishing advancements in numerous fields of study – particularly in the areas of regenerative medicine and personalized disease therapeutics. cache/r781wd40p83.txt txt/r781wd40p83.txt