id	sid	tid	token	lemma	pos
0g354f18w6x	1	1	antigen	antigen	NOUN
0g354f18w6x	1	2	specificity	specificity	NOUN
0g354f18w6x	1	3	is	be	AUX
0g354f18w6x	1	4	a	a	DET
0g354f18w6x	1	5	hallmark	hallmark	NOUN
0g354f18w6x	1	6	of	of	ADP
0g354f18w6x	1	7	t	t	PROPN
0g354f18w6x	1	8	cell	cell	NOUN
0g354f18w6x	1	9	immunity	immunity	NOUN
0g354f18w6x	1	10	.	.	PUNCT
0g354f18w6x	2	1	this	this	DET
0g354f18w6x	2	2	specificity	specificity	NOUN
0g354f18w6x	2	3	is	be	AUX
0g354f18w6x	2	4	dictated	dictate	VERB
0g354f18w6x	2	5	by	by	ADP
0g354f18w6x	2	6	the	the	DET
0g354f18w6x	2	7	t	t	PROPN
0g354f18w6x	2	8	cell	cell	NOUN
0g354f18w6x	2	9	receptor	receptor	NOUN
0g354f18w6x	2	10	(	(	PUNCT
0g354f18w6x	2	11	tcr	tcr	PROPN
0g354f18w6x	2	12	)	)	PUNCT
0g354f18w6x	2	13	,	,	PUNCT
0g354f18w6x	2	14	which	which	PRON
0g354f18w6x	2	15	recognizes	recognize	VERB
0g354f18w6x	2	16	peptide	peptide	NOUN
0g354f18w6x	2	17	antigens	antigen	NOUN
0g354f18w6x	2	18	bound	bind	VERB
0g354f18w6x	2	19	and	and	CCONJ
0g354f18w6x	2	20	presented	present	VERB
0g354f18w6x	2	21	by	by	ADP
0g354f18w6x	2	22	major	major	ADJ
0g354f18w6x	2	23	histocompatibility	histocompatibility	NOUN
0g354f18w6x	2	24	complex	complex	NOUN
0g354f18w6x	2	25	(	(	PUNCT
0g354f18w6x	2	26	mhc	mhc	NOUN
0g354f18w6x	2	27	)	)	PUNCT
0g354f18w6x	2	28	proteins	protein	NOUN
0g354f18w6x	2	29	using	use	VERB
0g354f18w6x	2	30	six	six	NUM
0g354f18w6x	2	31	complementarity	complementarity	NOUN
0g354f18w6x	2	32	determining	determining	NOUN
0g354f18w6x	2	33	region	region	NOUN
0g354f18w6x	2	34	(	(	PUNCT
0g354f18w6x	2	35	cdr	cdr	PROPN
0g354f18w6x	2	36	)	)	PUNCT
0g354f18w6x	2	37	loops	loop	NOUN
0g354f18w6x	2	38	.	.	PUNCT
0g354f18w6x	3	1	to	to	PART
0g354f18w6x	3	2	understand	understand	VERB
0g354f18w6x	3	3	the	the	DET
0g354f18w6x	3	4	molecular	molecular	ADJ
0g354f18w6x	3	5	basis	basis	NOUN
0g354f18w6x	3	6	of	of	ADP
0g354f18w6x	3	7	specificity	specificity	NOUN
0g354f18w6x	3	8	,	,	PUNCT
0g354f18w6x	3	9	i	i	PRON
0g354f18w6x	3	10	studied	study	VERB
0g354f18w6x	3	11	parental	parental	ADJ
0g354f18w6x	3	12	and	and	CCONJ
0g354f18w6x	3	13	engineered	engineered	ADJ
0g354f18w6x	3	14	tcrs	tcrs	NOUN
0g354f18w6x	3	15	whose	whose	DET
0g354f18w6x	3	16	specificity	specificity	NOUN
0g354f18w6x	3	17	had	have	AUX
0g354f18w6x	3	18	been	be	AUX
0g354f18w6x	3	19	switched	switch	VERB
0g354f18w6x	3	20	via	via	ADP
0g354f18w6x	3	21	molecular	molecular	ADJ
0g354f18w6x	3	22	evolution	evolution	NOUN
0g354f18w6x	3	23	along	along	ADP
0g354f18w6x	3	24	with	with	ADP
0g354f18w6x	3	25	a	a	DET
0g354f18w6x	3	26	clinically	clinically	ADV
0g354f18w6x	3	27	relevant	relevant	ADJ
0g354f18w6x	3	28	tcr	tcr	NOUN
0g354f18w6x	3	29	that	that	PRON
0g354f18w6x	3	30	recognizes	recognize	VERB
0g354f18w6x	3	31	a	a	DET
0g354f18w6x	3	32	non	non	ADJ
0g354f18w6x	3	33	-	-	ADJ
0g354f18w6x	3	34	cognate	cognate	ADJ
0g354f18w6x	3	35	mhc	mhc	NOUN
0g354f18w6x	3	36	.	.	PUNCT
0g354f18w6x	4	1	i	i	PRON
0g354f18w6x	4	2	,	,	PUNCT
0g354f18w6x	4	3	in	in	ADP
0g354f18w6x	4	4	conjunction	conjunction	NOUN
0g354f18w6x	4	5	with	with	ADP
0g354f18w6x	4	6	our	our	PRON
0g354f18w6x	4	7	collaborators	collaborator	NOUN
0g354f18w6x	4	8	at	at	ADP
0g354f18w6x	4	9	university	university	PROPN
0g354f18w6x	4	10	of	of	ADP
0g354f18w6x	4	11	illinois	illinois	PROPN
0g354f18w6x	4	12	and	and	CCONJ
0g354f18w6x	4	13	loyola	loyola	PROPN
0g354f18w6x	4	14	university	university	PROPN
0g354f18w6x	4	15	,	,	PUNCT
0g354f18w6x	4	16	combined	combine	VERB
0g354f18w6x	4	17	structural	structural	ADJ
0g354f18w6x	4	18	and	and	CCONJ
0g354f18w6x	4	19	functional	functional	ADJ
0g354f18w6x	4	20	analysis	analysis	NOUN
0g354f18w6x	4	21	with	with	ADP
0g354f18w6x	4	22	deep	deep	ADJ
0g354f18w6x	4	23	mutational	mutational	ADJ
0g354f18w6x	4	24	scanning	scanning	NOUN
0g354f18w6x	4	25	to	to	PART
0g354f18w6x	4	26	gain	gain	VERB
0g354f18w6x	4	27	insight	insight	NOUN
0g354f18w6x	4	28	into	into	ADP
0g354f18w6x	4	29	the	the	DET
0g354f18w6x	4	30	encoding	encoding	NOUN
0g354f18w6x	4	31	of	of	ADP
0g354f18w6x	4	32	tcr	tcr	NOUN
0g354f18w6x	4	33	specificity	specificity	NOUN
0g354f18w6x	4	34	.	.	PUNCT
0g354f18w6x	5	1	our	our	PRON
0g354f18w6x	5	2	findings	finding	NOUN
0g354f18w6x	5	3	showed	show	VERB
0g354f18w6x	5	4	that	that	SCONJ
0g354f18w6x	5	5	for	for	ADP
0g354f18w6x	5	6	tcrs	tcr	NOUN
0g354f18w6x	5	7	with	with	ADP
0g354f18w6x	5	8	engineered	engineer	VERB
0g354f18w6x	5	9	antigen	antigen	NOUN
0g354f18w6x	5	10	specificity	specificity	NOUN
0g354f18w6x	5	11	,	,	PUNCT
0g354f18w6x	5	12	the	the	DET
0g354f18w6x	5	13	amino	amino	ADJ
0g354f18w6x	5	14	acid	acid	NOUN
0g354f18w6x	5	15	substitutions	substitution	NOUN
0g354f18w6x	5	16	controlled	control	VERB
0g354f18w6x	5	17	the	the	DET
0g354f18w6x	5	18	tcr	tcr	PROPN
0g354f18w6x	5	19	binding	bind	VERB
0g354f18w6x	5	20	mode	mode	NOUN
0g354f18w6x	5	21	and	and	CCONJ
0g354f18w6x	5	22	thus	thus	ADV
0g354f18w6x	5	23	the	the	DET
0g354f18w6x	5	24	interactions	interaction	NOUN
0g354f18w6x	5	25	throughout	throughout	ADP
0g354f18w6x	5	26	the	the	DET
0g354f18w6x	5	27	interface	interface	NOUN
0g354f18w6x	5	28	.	.	PUNCT
0g354f18w6x	6	1	overall	overall	ADV
0g354f18w6x	6	2	,	,	PUNCT
0g354f18w6x	6	3	our	our	PRON
0g354f18w6x	6	4	results	result	NOUN
0g354f18w6x	6	5	show	show	VERB
0g354f18w6x	6	6	that	that	SCONJ
0g354f18w6x	6	7	the	the	DET
0g354f18w6x	6	8	positions	position	NOUN
0g354f18w6x	6	9	on	on	ADP
0g354f18w6x	6	10	the	the	DET
0g354f18w6x	6	11	cdr	cdr	PROPN
0g354f18w6x	6	12	loops	loop	NOUN
0g354f18w6x	6	13	associated	associate	VERB
0g354f18w6x	6	14	with	with	ADP
0g354f18w6x	6	15	antigen	antigen	NOUN
0g354f18w6x	6	16	specificity	specificity	NOUN
0g354f18w6x	6	17	are	be	AUX
0g354f18w6x	6	18	broadly	broadly	ADV
0g354f18w6x	6	19	distributed	distribute	VERB
0g354f18w6x	6	20	among	among	ADP
0g354f18w6x	6	21	the	the	DET
0g354f18w6x	6	22	germline	germline	NOUN
0g354f18w6x	6	23	and	and	CCONJ
0g354f18w6x	6	24	hypervariable	hypervariable	ADJ
0g354f18w6x	6	25	loops	loop	NOUN
0g354f18w6x	6	26	,	,	PUNCT
0g354f18w6x	6	27	and	and	CCONJ
0g354f18w6x	6	28	include	include	VERB
0g354f18w6x	6	29	interactions	interaction	NOUN
0g354f18w6x	6	30	with	with	ADP
0g354f18w6x	6	31	both	both	CCONJ
0g354f18w6x	6	32	the	the	DET
0g354f18w6x	6	33	peptide	peptide	NOUN
0g354f18w6x	6	34	and	and	CCONJ
0g354f18w6x	6	35	mhc	mhc	ADJ
0g354f18w6x	6	36	protein	protein	NOUN
0g354f18w6x	6	37	,	,	PUNCT
0g354f18w6x	6	38	with	with	ADP
0g354f18w6x	6	39	significant	significant	ADJ
0g354f18w6x	6	40	implication	implication	NOUN
0g354f18w6x	6	41	for	for	ADP
0g354f18w6x	6	42	engineering	engineering	NOUN
0g354f18w6x	6	43	tcrs	tcr	NOUN
0g354f18w6x	6	44	with	with	ADP
0g354f18w6x	6	45	novel	novel	ADJ
0g354f18w6x	6	46	binding	bind	VERB
0g354f18w6x	6	47	properties	property	NOUN
0g354f18w6x	6	48	.	.	PUNCT