id sid tid token lemma pos 3f462517k95 1 1 this this DET 3f462517k95 1 2 dissertation dissertation NOUN 3f462517k95 1 3 describes describe VERB 3f462517k95 1 4 two two NUM 3f462517k95 1 5 main main ADJ 3f462517k95 1 6 research research NOUN 3f462517k95 1 7 topics topic NOUN 3f462517k95 1 8 that that PRON 3f462517k95 1 9 are be AUX 3f462517k95 1 10 associated associate VERB 3f462517k95 1 11 with with ADP 3f462517k95 1 12 the the DET 3f462517k95 1 13 development development NOUN 3f462517k95 1 14 of of ADP 3f462517k95 1 15 effective effective ADJ 3f462517k95 1 16 treatments treatment NOUN 3f462517k95 1 17 for for ADP 3f462517k95 1 18 the the DET 3f462517k95 1 19 common common ADJ 3f462517k95 1 20 diseases disease NOUN 3f462517k95 1 21 , , PUNCT 3f462517k95 1 22 cancer cancer NOUN 3f462517k95 1 23 and and CCONJ 3f462517k95 1 24 allergy allergy NOUN 3f462517k95 1 25 . . PUNCT 3f462517k95 2 1 the the DET 3f462517k95 2 2 1st 1st ADJ 3f462517k95 2 3 part part NOUN 3f462517k95 2 4 of of ADP 3f462517k95 2 5 this this DET 3f462517k95 2 6 dissertation dissertation NOUN 3f462517k95 2 7 will will AUX 3f462517k95 2 8 describe describe VERB 3f462517k95 2 9 the the DET 3f462517k95 2 10 design design NOUN 3f462517k95 2 11 , , PUNCT 3f462517k95 2 12 synthesis synthesis NOUN 3f462517k95 2 13 , , PUNCT 3f462517k95 2 14 characterization characterization NOUN 3f462517k95 2 15 , , PUNCT 3f462517k95 2 16 and and CCONJ 3f462517k95 2 17 optimization optimization NOUN 3f462517k95 2 18 of of ADP 3f462517k95 2 19 peptide peptide NOUN 3f462517k95 2 20 - - PUNCT 3f462517k95 2 21 targeted target VERB 3f462517k95 2 22 liposomal liposomal ADJ 3f462517k95 2 23 nanoparticles nanoparticle NOUN 3f462517k95 2 24 that that PRON 3f462517k95 2 25 show show VERB 3f462517k95 2 26 enhanced enhance VERB 3f462517k95 2 27 selectivity selectivity NOUN 3f462517k95 2 28 to to ADP 3f462517k95 2 29 cancer cancer NOUN 3f462517k95 2 30 cells cell NOUN 3f462517k95 2 31 including include VERB 3f462517k95 2 32 her2 her2 PROPN 3f462517k95 2 33 + + CCONJ 3f462517k95 2 34 breast breast NOUN 3f462517k95 2 35 cancer cancer NOUN 3f462517k95 2 36 , , PUNCT 3f462517k95 2 37 cd22 cd22 PROPN 3f462517k95 2 38 + + SYM 3f462517k95 2 39 blood blood NOUN 3f462517k95 2 40 cancer cancer NOUN 3f462517k95 2 41 , , PUNCT 3f462517k95 2 42 grp78 grp78 PROPN 3f462517k95 2 43 + + CCONJ 3f462517k95 2 44 metastatic metastatic ADJ 3f462517k95 2 45 breast breast NOUN 3f462517k95 2 46 cancer cancer NOUN 3f462517k95 2 47 , , PUNCT 3f462517k95 2 48 and and CCONJ 3f462517k95 2 49 multiple multiple ADJ 3f462517k95 2 50 myeloma myeloma NOUN 3f462517k95 2 51 . . PUNCT 3f462517k95 3 1 targeted targeted ADJ 3f462517k95 3 2 nanoparticle nanoparticle NOUN 3f462517k95 3 3 drug drug NOUN 3f462517k95 3 4 delivery delivery NOUN 3f462517k95 3 5 systems system NOUN 3f462517k95 3 6 have have AUX 3f462517k95 3 7 widely widely ADV 3f462517k95 3 8 been be AUX 3f462517k95 3 9 investigated investigate VERB 3f462517k95 3 10 to to PART 3f462517k95 3 11 combat combat VERB 3f462517k95 3 12 a a DET 3f462517k95 3 13 variety variety NOUN 3f462517k95 3 14 of of ADP 3f462517k95 3 15 cancers cancer NOUN 3f462517k95 3 16 , , PUNCT 3f462517k95 3 17 however however ADV 3f462517k95 3 18 , , PUNCT 3f462517k95 3 19 have have AUX 3f462517k95 3 20 not not PART 3f462517k95 3 21 yet yet ADV 3f462517k95 3 22 successfully successfully ADV 3f462517k95 3 23 translated translate VERB 3f462517k95 3 24 into into ADP 3f462517k95 3 25 the the DET 3f462517k95 3 26 clinic clinic NOUN 3f462517k95 3 27 . . PUNCT 3f462517k95 4 1 for for ADP 3f462517k95 4 2 successful successful ADJ 3f462517k95 4 3 clinical clinical ADJ 3f462517k95 4 4 translation translation NOUN 3f462517k95 4 5 , , PUNCT 3f462517k95 4 6 we we PRON 3f462517k95 4 7 employed employ VERB 3f462517k95 4 8 our our PRON 3f462517k95 4 9 synthetic synthetic ADJ 3f462517k95 4 10 strategy strategy NOUN 3f462517k95 4 11 that that PRON 3f462517k95 4 12 enables enable VERB 3f462517k95 4 13 reproducible reproducible VERB 3f462517k95 4 14 and and CCONJ 3f462517k95 4 15 reliable reliable ADJ 3f462517k95 4 16 nanoparticle nanoparticle NOUN 3f462517k95 4 17 production production NOUN 3f462517k95 4 18 with with ADP 3f462517k95 4 19 high high ADJ 3f462517k95 4 20 precision precision NOUN 3f462517k95 4 21 in in ADP 3f462517k95 4 22 targeting target VERB 3f462517k95 4 23 functionalities functionality NOUN 3f462517k95 4 24 . . PUNCT 3f462517k95 5 1 additionally additionally ADV 3f462517k95 5 2 , , PUNCT 3f462517k95 5 3 we we PRON 3f462517k95 5 4 exploited exploit VERB 3f462517k95 5 5 multivalency multivalency NOUN 3f462517k95 5 6 with with ADP 3f462517k95 5 7 moderate moderate ADJ 3f462517k95 5 8 affinity affinity NOUN 3f462517k95 5 9 receptor receptor NOUN 3f462517k95 5 10 - - PUNCT 3f462517k95 5 11 binding bind VERB 3f462517k95 5 12 peptides peptide NOUN 3f462517k95 5 13 as as ADP 3f462517k95 5 14 targeting target VERB 3f462517k95 5 15 moieties moiety NOUN 3f462517k95 5 16 of of ADP 3f462517k95 5 17 nanoparticles nanoparticle NOUN 3f462517k95 5 18 . . PUNCT 3f462517k95 6 1 multiple multiple ADJ 3f462517k95 6 2 nanoparticle nanoparticle NOUN 3f462517k95 6 3 design design NOUN 3f462517k95 6 4 parameters parameter NOUN 3f462517k95 6 5 were be AUX 3f462517k95 6 6 both both PRON 3f462517k95 6 7 in in ADP 3f462517k95 6 8 vitro vitro X 3f462517k95 6 9 and and CCONJ 3f462517k95 6 10 in in ADP 3f462517k95 6 11 vivo vivo NOUN 3f462517k95 6 12 optimized optimize VERB 3f462517k95 6 13 to to PART 3f462517k95 6 14 accomplish accomplish VERB 3f462517k95 6 15 enhanced enhanced ADJ 3f462517k95 6 16 target target NOUN 3f462517k95 6 17 cancer cancer NOUN 3f462517k95 6 18 cell cell NOUN 3f462517k95 6 19 selectivity selectivity ADJ 3f462517k95 6 20 in in ADP 3f462517k95 6 21 order order NOUN 3f462517k95 6 22 to to PART 3f462517k95 6 23 improve improve VERB 3f462517k95 6 24 tumor tumor NOUN 3f462517k95 6 25 growth growth NOUN 3f462517k95 6 26 inhibition inhibition NOUN 3f462517k95 6 27 efficacy efficacy NOUN 3f462517k95 6 28 of of ADP 3f462517k95 6 29 chemotherapeutic chemotherapeutic ADJ 3f462517k95 6 30 agents agent NOUN 3f462517k95 6 31 with with ADP 3f462517k95 6 32 minimal minimal ADJ 3f462517k95 6 33 toxicity toxicity NOUN 3f462517k95 6 34 . . PUNCT 3f462517k95 7 1 we we PRON 3f462517k95 7 2 demonstrated demonstrate VERB 3f462517k95 7 3 that that SCONJ 3f462517k95 7 4 the the DET 3f462517k95 7 5 targeted target VERB 3f462517k95 7 6 nanoparticle nanoparticle NOUN 3f462517k95 7 7 formulations formulation NOUN 3f462517k95 7 8 outperformed outperform VERB 3f462517k95 7 9 non non ADJ 3f462517k95 7 10 - - ADJ 3f462517k95 7 11 targeted targeted ADJ 3f462517k95 7 12 counterparts counterpart NOUN 3f462517k95 7 13 given give VERB 3f462517k95 7 14 enhanced enhance VERB 3f462517k95 7 15 anti anti ADJ 3f462517k95 7 16 - - ADJ 3f462517k95 7 17 tumor tumor ADJ 3f462517k95 7 18 efficacy efficacy NOUN 3f462517k95 7 19 via via ADP 3f462517k95 7 20 tumor tumor NOUN 3f462517k95 7 21 cell cell NOUN 3f462517k95 7 22 - - PUNCT 3f462517k95 7 23 selective selective ADJ 3f462517k95 7 24 uptake uptake NOUN 3f462517k95 7 25 with with ADP 3f462517k95 7 26 high high ADJ 3f462517k95 7 27 therapeutic therapeutic ADJ 3f462517k95 7 28 indices index NOUN 3f462517k95 7 29 . . PUNCT 3f462517k95 8 1 this this PRON 3f462517k95 8 2 suggests suggest VERB 3f462517k95 8 3 a a DET 3f462517k95 8 4 high high ADJ 3f462517k95 8 5 therapeutic therapeutic ADJ 3f462517k95 8 6 potential potential NOUN 3f462517k95 8 7 of of ADP 3f462517k95 8 8 the the DET 3f462517k95 8 9 peptide peptide NOUN 3f462517k95 8 10 - - PUNCT 3f462517k95 8 11 targeted target VERB 3f462517k95 8 12 nanoparticles nanoparticle NOUN 3f462517k95 8 13 to to PART 3f462517k95 8 14 improve improve VERB 3f462517k95 8 15 patient patient ADJ 3f462517k95 8 16 outcomes outcome NOUN 3f462517k95 8 17 in in ADP 3f462517k95 8 18 the the DET 3f462517k95 8 19 clinic.the clinic.the DET 3f462517k95 8 20 2nd 2nd ADJ 3f462517k95 8 21 part part NOUN 3f462517k95 8 22 of of ADP 3f462517k95 8 23 this this DET 3f462517k95 8 24 dissertation dissertation NOUN 3f462517k95 8 25 will will AUX 3f462517k95 8 26 describe describe VERB 3f462517k95 8 27 the the DET 3f462517k95 8 28 development development NOUN 3f462517k95 8 29 of of ADP 3f462517k95 8 30 inhibitors inhibitor NOUN 3f462517k95 8 31 for for ADP 3f462517k95 8 32 food food NOUN 3f462517k95 8 33 allergic allergic ADJ 3f462517k95 8 34 reactions reaction NOUN 3f462517k95 8 35 . . PUNCT 3f462517k95 9 1 currently currently ADV 3f462517k95 9 2 , , PUNCT 3f462517k95 9 3 there there PRON 3f462517k95 9 4 are be VERB 3f462517k95 9 5 no no DET 3f462517k95 9 6 treatments treatment NOUN 3f462517k95 9 7 that that PRON 3f462517k95 9 8 effectively effectively ADV 3f462517k95 9 9 prevent prevent VERB 3f462517k95 9 10 allergic allergic ADJ 3f462517k95 9 11 reactions reaction NOUN 3f462517k95 9 12 . . PUNCT 3f462517k95 10 1 allergic allergic ADJ 3f462517k95 10 2 reactions reaction NOUN 3f462517k95 10 3 are be AUX 3f462517k95 10 4 triggered trigger VERB 3f462517k95 10 5 by by ADP 3f462517k95 10 6 crosslinking crosslinke VERB 3f462517k95 10 7 of of ADP 3f462517k95 10 8 several several ADJ 3f462517k95 10 9 immunoglobulin immunoglobulin NOUN 3f462517k95 10 10 e e NOUN 3f462517k95 10 11 ( ( PUNCT 3f462517k95 10 12 ige ige PROPN 3f462517k95 10 13 ) ) PUNCT 3f462517k95 10 14 antibodies antibody NOUN 3f462517k95 10 15 on on ADP 3f462517k95 10 16 immune immune ADJ 3f462517k95 10 17 cells cell NOUN 3f462517k95 10 18 with with ADP 3f462517k95 10 19 multiple multiple ADJ 3f462517k95 10 20 epitopes epitope NOUN 3f462517k95 10 21 on on ADP 3f462517k95 10 22 an an DET 3f462517k95 10 23 allergen allergen NOUN 3f462517k95 10 24 . . PUNCT 3f462517k95 11 1 in in ADP 3f462517k95 11 2 light light NOUN 3f462517k95 11 3 of of ADP 3f462517k95 11 4 this this PRON 3f462517k95 11 5 , , PUNCT 3f462517k95 11 6 a a DET 3f462517k95 11 7 key key ADJ 3f462517k95 11 8 point point NOUN 3f462517k95 11 9 in in ADP 3f462517k95 11 10 developing develop VERB 3f462517k95 11 11 preventative preventative ADJ 3f462517k95 11 12 allergy allergy NOUN 3f462517k95 11 13 medicine medicine NOUN 3f462517k95 11 14 is be AUX 3f462517k95 11 15 to to PART 3f462517k95 11 16 inhibit inhibit VERB 3f462517k95 11 17 epitope epitope ADJ 3f462517k95 11 18 - - PUNCT 3f462517k95 11 19 ige ige NOUN 3f462517k95 11 20 interactions interaction NOUN 3f462517k95 11 21 . . PUNCT 3f462517k95 12 1 by by ADP 3f462517k95 12 2 using use VERB 3f462517k95 12 3 nanoallergen nanoallergen PROPN 3f462517k95 12 4 platform platform NOUN 3f462517k95 12 5 displaying display VERB 3f462517k95 12 6 epitope epitope NOUN 3f462517k95 12 7 alone alone ADV 3f462517k95 12 8 or or CCONJ 3f462517k95 12 9 in in ADP 3f462517k95 12 10 combination combination NOUN 3f462517k95 12 11 , , PUNCT 3f462517k95 12 12 we we PRON 3f462517k95 12 13 determined determine VERB 3f462517k95 12 14 and and CCONJ 3f462517k95 12 15 ranked rank VERB 3f462517k95 12 16 epitope epitope NOUN 3f462517k95 12 17 of of ADP 3f462517k95 12 18 importance importance NOUN 3f462517k95 12 19 according accord VERB 3f462517k95 12 20 to to ADP 3f462517k95 12 21 epitope epitope NOUN 3f462517k95 12 22 immunogenicity immunogenicity NOUN 3f462517k95 12 23 . . PUNCT 3f462517k95 13 1 this this DET 3f462517k95 13 2 information information NOUN 3f462517k95 13 3 was be AUX 3f462517k95 13 4 implemented implement VERB 3f462517k95 13 5 to to PART 3f462517k95 13 6 generate generate VERB 3f462517k95 13 7 various various ADJ 3f462517k95 13 8 covalent covalent NOUN 3f462517k95 13 9 heterobivalent heterobivalent ADJ 3f462517k95 13 10 inhibitor inhibitor NOUN 3f462517k95 13 11 ( ( PUNCT 3f462517k95 13 12 chbi chbi PROPN 3f462517k95 13 13 ) ) PUNCT 3f462517k95 13 14 mixtures mixture NOUN 3f462517k95 13 15 to to PART 3f462517k95 13 16 test test VERB 3f462517k95 13 17 their their PRON 3f462517k95 13 18 inhibition inhibition NOUN 3f462517k95 13 19 efficacy efficacy NOUN 3f462517k95 13 20 for for ADP 3f462517k95 13 21 allergic allergic ADJ 3f462517k95 13 22 response response NOUN 3f462517k95 13 23 . . PUNCT 3f462517k95 14 1 the the DET 3f462517k95 14 2 results result NOUN 3f462517k95 14 3 demonstrated demonstrate VERB 3f462517k95 14 4 & & CCONJ 3f462517k95 14 5 gt gt PROPN 3f462517k95 14 6 ; ; PUNCT 3f462517k95 14 7 90 90 NUM 3f462517k95 14 8 % % NOUN 3f462517k95 14 9 of of ADP 3f462517k95 14 10 inhibition inhibition NOUN 3f462517k95 14 11 of of ADP 3f462517k95 14 12 allergic allergic ADJ 3f462517k95 14 13 response response NOUN 3f462517k95 14 14 mediated mediate VERB 3f462517k95 14 15 by by ADP 3f462517k95 14 16 crude crude ADJ 3f462517k95 14 17 peanut peanut NOUN 3f462517k95 14 18 extract extract NOUN 3f462517k95 14 19 and and CCONJ 3f462517k95 14 20 a a DET 3f462517k95 14 21 major major ADJ 3f462517k95 14 22 shrimp shrimp NOUN 3f462517k95 14 23 allergen allergen NOUN 3f462517k95 14 24 , , PUNCT 3f462517k95 14 25 pen pen VERB 3f462517k95 14 26 a a DET 3f462517k95 14 27 1 1 NUM 3f462517k95 14 28 . . PUNCT 3f462517k95 15 1 although although SCONJ 3f462517k95 15 2 further further ADJ 3f462517k95 15 3 studies study NOUN 3f462517k95 15 4 are be AUX 3f462517k95 15 5 necessary necessary ADJ 3f462517k95 15 6 , , PUNCT 3f462517k95 15 7 these these DET 3f462517k95 15 8 promising promising ADJ 3f462517k95 15 9 results result NOUN 3f462517k95 15 10 provide provide VERB 3f462517k95 15 11 evidence evidence NOUN 3f462517k95 15 12 for for ADP 3f462517k95 15 13 the the DET 3f462517k95 15 14 potential potential NOUN 3f462517k95 15 15 of of ADP 3f462517k95 15 16 nanoallergens nanoallergen NOUN 3f462517k95 15 17 and and CCONJ 3f462517k95 15 18 chbis chbi NOUN 3f462517k95 15 19 for for ADP 3f462517k95 15 20 the the DET 3f462517k95 15 21 diagnosis diagnosis NOUN 3f462517k95 15 22 and and CCONJ 3f462517k95 15 23 treatment treatment NOUN 3f462517k95 15 24 of of ADP 3f462517k95 15 25 food food NOUN 3f462517k95 15 26 allergies allergy NOUN 3f462517k95 15 27 . . PUNCT