id sid tid token lemma pos 4x51hh65t3n 1 1 islets islet NOUN 4x51hh65t3n 1 2 of of ADP 4x51hh65t3n 1 3 langerhans langerhans PROPN 4x51hh65t3n 1 4 are be AUX 4x51hh65t3n 1 5 critical critical ADJ 4x51hh65t3n 1 6 for for ADP 4x51hh65t3n 1 7 the the DET 4x51hh65t3n 1 8 homeostasis homeostasis NOUN 4x51hh65t3n 1 9 of of ADP 4x51hh65t3n 1 10 blood blood NOUN 4x51hh65t3n 1 11 glucose glucose NOUN 4x51hh65t3n 1 12 levels level NOUN 4x51hh65t3n 1 13 . . PUNCT 4x51hh65t3n 2 1 islets islet NOUN 4x51hh65t3n 2 2 secrete secrete VERB 4x51hh65t3n 2 3 antagonistic antagonistic ADJ 4x51hh65t3n 2 4 protein protein NOUN 4x51hh65t3n 2 5 hormones hormone NOUN 4x51hh65t3n 2 6 to to PART 4x51hh65t3n 2 7 regulate regulate VERB 4x51hh65t3n 2 8 blood blood NOUN 4x51hh65t3n 2 9 sugar sugar NOUN 4x51hh65t3n 2 10 . . PUNCT 4x51hh65t3n 3 1 dysregulation dysregulation NOUN 4x51hh65t3n 3 2 or or CCONJ 4x51hh65t3n 3 3 damage damage NOUN 4x51hh65t3n 3 4 of of ADP 4x51hh65t3n 3 5 islets islet NOUN 4x51hh65t3n 3 6 can can AUX 4x51hh65t3n 3 7 cause cause VERB 4x51hh65t3n 3 8 diabetes diabetes NOUN 4x51hh65t3n 3 9 , , PUNCT 4x51hh65t3n 3 10 a a DET 4x51hh65t3n 3 11 metabolic metabolic NOUN 4x51hh65t3n 3 12 disease disease NOUN 4x51hh65t3n 3 13 characterized characterize VERB 4x51hh65t3n 3 14 by by ADP 4x51hh65t3n 3 15 persistent persistent ADJ 4x51hh65t3n 3 16 high high ADJ 4x51hh65t3n 3 17 blood blood NOUN 4x51hh65t3n 3 18 glucose glucose NOUN 4x51hh65t3n 3 19 levels level NOUN 4x51hh65t3n 3 20 . . PUNCT 4x51hh65t3n 4 1 as as SCONJ 4x51hh65t3n 4 2 islets islet NOUN 4x51hh65t3n 4 3 are be AUX 4x51hh65t3n 4 4 the the DET 4x51hh65t3n 4 5 primarily primarily ADV 4x51hh65t3n 4 6 responsible responsible ADJ 4x51hh65t3n 4 7 for for ADP 4x51hh65t3n 4 8 blood blood NOUN 4x51hh65t3n 4 9 glucose glucose NOUN 4x51hh65t3n 4 10 interrogating interrogate VERB 4x51hh65t3n 4 11 the the DET 4x51hh65t3n 4 12 fundamental fundamental ADJ 4x51hh65t3n 4 13 alterations alteration NOUN 4x51hh65t3n 4 14 helps helps AUX 4x51hh65t3n 4 15 elucidate elucidate VERB 4x51hh65t3n 4 16 causation causation NOUN 4x51hh65t3n 4 17 and and CCONJ 4x51hh65t3n 4 18 helps help VERB 4x51hh65t3n 4 19 provide provide VERB 4x51hh65t3n 4 20 a a DET 4x51hh65t3n 4 21 holistic holistic ADJ 4x51hh65t3n 4 22 understanding understanding NOUN 4x51hh65t3n 4 23 of of ADP 4x51hh65t3n 4 24 the the DET 4x51hh65t3n 4 25 disease disease NOUN 4x51hh65t3n 4 26 . . PUNCT 4x51hh65t3n 5 1 in in ADP 4x51hh65t3n 5 2 this this DET 4x51hh65t3n 5 3 work work NOUN 4x51hh65t3n 5 4 , , PUNCT 4x51hh65t3n 5 5 i i PRON 4x51hh65t3n 5 6 present present VERB 4x51hh65t3n 5 7 a a DET 4x51hh65t3n 5 8 systematic systematic ADJ 4x51hh65t3n 5 9 study study NOUN 4x51hh65t3n 5 10 of of ADP 4x51hh65t3n 5 11 the the DET 4x51hh65t3n 5 12 secretome secretome NOUN 4x51hh65t3n 5 13 , , PUNCT 4x51hh65t3n 5 14 or or CCONJ 4x51hh65t3n 5 15 secreted secrete VERB 4x51hh65t3n 5 16 protein protein NOUN 4x51hh65t3n 5 17 content content NOUN 4x51hh65t3n 5 18 , , PUNCT 4x51hh65t3n 5 19 of of ADP 4x51hh65t3n 5 20 murine murine NOUN 4x51hh65t3n 5 21 islets islet NOUN 4x51hh65t3n 5 22 of of ADP 4x51hh65t3n 5 23 langerhans langerhan NOUN 4x51hh65t3n 5 24 . . PUNCT 4x51hh65t3n 6 1 in in ADP 4x51hh65t3n 6 2 particular particular ADJ 4x51hh65t3n 6 3 , , PUNCT 4x51hh65t3n 6 4 i i PRON 4x51hh65t3n 6 5 focused focus VERB 4x51hh65t3n 6 6 on on ADP 4x51hh65t3n 6 7 optimizing optimize VERB 4x51hh65t3n 6 8 a a DET 4x51hh65t3n 6 9 bottom bottom ADJ 4x51hh65t3n 6 10 - - PUNCT 4x51hh65t3n 6 11 up up ADP 4x51hh65t3n 6 12 proteomic proteomic ADJ 4x51hh65t3n 6 13 approach approach NOUN 4x51hh65t3n 6 14 for for ADP 4x51hh65t3n 6 15 analysis analysis NOUN 4x51hh65t3n 6 16 with with ADP 4x51hh65t3n 6 17 liquid liquid ADJ 4x51hh65t3n 6 18 chromatography chromatography NOUN 4x51hh65t3n 6 19 - - PUNCT 4x51hh65t3n 6 20 tandem tandem NOUN 4x51hh65t3n 6 21 mass mass NOUN 4x51hh65t3n 6 22 spectrometry spectrometry NOUN 4x51hh65t3n 6 23 ( ( PUNCT 4x51hh65t3n 6 24 lc lc PROPN 4x51hh65t3n 6 25 - - PUNCT 4x51hh65t3n 6 26 ms ms PROPN 4x51hh65t3n 6 27 / / SYM 4x51hh65t3n 6 28 ms ms PROPN 4x51hh65t3n 6 29 ) ) PUNCT 4x51hh65t3n 6 30 . . PUNCT 4x51hh65t3n 7 1 additionally additionally ADV 4x51hh65t3n 7 2 , , PUNCT 4x51hh65t3n 7 3 the the DET 4x51hh65t3n 7 4 effects effect NOUN 4x51hh65t3n 7 5 of of ADP 4x51hh65t3n 7 6 elevated elevated ADJ 4x51hh65t3n 7 7 glucose glucose NOUN 4x51hh65t3n 7 8 levels level NOUN 4x51hh65t3n 7 9 on on ADP 4x51hh65t3n 7 10 the the DET 4x51hh65t3n 7 11 secretome secretome NOUN 4x51hh65t3n 7 12 were be AUX 4x51hh65t3n 7 13 studied study VERB 4x51hh65t3n 7 14 to to PART 4x51hh65t3n 7 15 better well ADV 4x51hh65t3n 7 16 understand understand VERB 4x51hh65t3n 7 17 the the DET 4x51hh65t3n 7 18 effects effect NOUN 4x51hh65t3n 7 19 of of ADP 4x51hh65t3n 7 20 diabetes diabetes NOUN 4x51hh65t3n 7 21 . . PUNCT