id	sid	tid	token	lemma	pos
8623hx14s61	1	1	the	the	DET
8623hx14s61	1	2	discovery	discovery	NOUN
8623hx14s61	1	3	of	of	ADP
8623hx14s61	1	4	antibiotics	antibiotic	NOUN
8623hx14s61	1	5	was	be	AUX
8623hx14s61	1	6	one	one	NUM
8623hx14s61	1	7	of	of	ADP
8623hx14s61	1	8	the	the	DET
8623hx14s61	1	9	greatest	great	ADJ
8623hx14s61	1	10	medical	medical	ADJ
8623hx14s61	1	11	discoveries	discovery	NOUN
8623hx14s61	1	12	of	of	ADP
8623hx14s61	1	13	the	the	DET
8623hx14s61	1	14	20th	20th	ADJ
8623hx14s61	1	15	century	century	NOUN
8623hx14s61	1	16	.	.	PUNCT
8623hx14s61	2	1	infectious	infectious	ADJ
8623hx14s61	2	2	diseases	disease	NOUN
8623hx14s61	2	3	were	be	AUX
8623hx14s61	2	4	rampant	rampant	ADJ
8623hx14s61	2	5	prior	prior	ADV
8623hx14s61	2	6	to	to	ADP
8623hx14s61	2	7	the	the	DET
8623hx14s61	2	8	discovery	discovery	NOUN
8623hx14s61	2	9	of	of	ADP
8623hx14s61	2	10	antibiotics	antibiotic	NOUN
8623hx14s61	2	11	,	,	PUNCT
8623hx14s61	2	12	which	which	PRON
8623hx14s61	2	13	resulted	result	VERB
8623hx14s61	2	14	in	in	ADP
8623hx14s61	2	15	high	high	ADJ
8623hx14s61	2	16	morbidity	morbidity	NOUN
8623hx14s61	2	17	and	and	CCONJ
8623hx14s61	2	18	mortality	mortality	NOUN
8623hx14s61	2	19	rates	rate	NOUN
8623hx14s61	2	20	.	.	PUNCT
8623hx14s61	3	1	in	in	ADP
8623hx14s61	3	2	fact	fact	NOUN
8623hx14s61	3	3	,	,	PUNCT
8623hx14s61	3	4	prior	prior	ADV
8623hx14s61	3	5	to	to	ADP
8623hx14s61	3	6	the	the	DET
8623hx14s61	3	7	antibiotic	antibiotic	ADJ
8623hx14s61	3	8	revolution	revolution	NOUN
8623hx14s61	3	9	,	,	PUNCT
8623hx14s61	3	10	the	the	DET
8623hx14s61	3	11	average	average	ADJ
8623hx14s61	3	12	life	life	NOUN
8623hx14s61	3	13	expectancy	expectancy	NOUN
8623hx14s61	3	14	at	at	ADP
8623hx14s61	3	15	birth	birth	NOUN
8623hx14s61	3	16	in	in	ADP
8623hx14s61	3	17	the	the	DET
8623hx14s61	3	18	united	united	PROPN
8623hx14s61	3	19	states	states	PROPN
8623hx14s61	3	20	was	be	AUX
8623hx14s61	3	21	a	a	DET
8623hx14s61	3	22	mere	mere	ADJ
8623hx14s61	3	23	47	47	NUM
8623hx14s61	3	24	years	year	NOUN
8623hx14s61	3	25	.	.	PUNCT
8623hx14s61	4	1	in	in	ADP
8623hx14s61	4	2	comparison	comparison	NOUN
8623hx14s61	4	3	,	,	PUNCT
8623hx14s61	4	4	today	today	NOUN
8623hx14s61	4	5	the	the	DET
8623hx14s61	4	6	average	average	ADJ
8623hx14s61	4	7	life	life	NOUN
8623hx14s61	4	8	expectancy	expectancy	NOUN
8623hx14s61	4	9	at	at	ADP
8623hx14s61	4	10	birth	birth	NOUN
8623hx14s61	4	11	is	be	AUX
8623hx14s61	4	12	78	78	NUM
8623hx14s61	4	13	years	year	NOUN
8623hx14s61	4	14	,	,	PUNCT
8623hx14s61	4	15	and	and	CCONJ
8623hx14s61	4	16	the	the	DET
8623hx14s61	4	17	leading	lead	VERB
8623hx14s61	4	18	causes	cause	NOUN
8623hx14s61	4	19	of	of	ADP
8623hx14s61	4	20	death	death	NOUN
8623hx14s61	4	21	are	be	AUX
8623hx14s61	4	22	no	no	ADV
8623hx14s61	4	23	longer	long	ADV
8623hx14s61	4	24	infectious	infectious	ADJ
8623hx14s61	4	25	diseases	disease	NOUN
8623hx14s61	4	26	,	,	PUNCT
8623hx14s61	4	27	but	but	CCONJ
8623hx14s61	4	28	rather	rather	ADV
8623hx14s61	4	29	are	be	AUX
8623hx14s61	4	30	due	due	ADJ
8623hx14s61	4	31	to	to	ADP
8623hx14s61	4	32	non	non	ADJ
8623hx14s61	4	33	-	-	ADJ
8623hx14s61	4	34	communicable	communicable	ADJ
8623hx14s61	4	35	diseases	disease	NOUN
8623hx14s61	4	36	such	such	ADJ
8623hx14s61	4	37	as	as	ADP
8623hx14s61	4	38	cardiovascular	cardiovascular	ADJ
8623hx14s61	4	39	disease	disease	NOUN
8623hx14s61	4	40	and	and	CCONJ
8623hx14s61	4	41	cancer	cancer	NOUN
8623hx14s61	4	42	.	.	PUNCT
8623hx14s61	5	1	antibiotics	antibiotic	NOUN
8623hx14s61	5	2	have	have	AUX
8623hx14s61	5	3	been	be	AUX
8623hx14s61	5	4	tremendously	tremendously	ADV
8623hx14s61	5	5	successful	successful	ADJ
8623hx14s61	5	6	in	in	ADP
8623hx14s61	5	7	increasing	increase	VERB
8623hx14s61	5	8	the	the	DET
8623hx14s61	5	9	quality	quality	NOUN
8623hx14s61	5	10	and	and	CCONJ
8623hx14s61	5	11	duration	duration	NOUN
8623hx14s61	5	12	of	of	ADP
8623hx14s61	5	13	human	human	ADJ
8623hx14s61	5	14	life	life	NOUN
8623hx14s61	5	15	,	,	PUNCT
8623hx14s61	5	16	but	but	CCONJ
8623hx14s61	5	17	we	we	PRON
8623hx14s61	5	18	are	be	AUX
8623hx14s61	5	19	currently	currently	ADV
8623hx14s61	5	20	in	in	ADP
8623hx14s61	5	21	the	the	DET
8623hx14s61	5	22	midst	midst	NOUN
8623hx14s61	5	23	of	of	ADP
8623hx14s61	5	24	a	a	DET
8623hx14s61	5	25	health	health	NOUN
8623hx14s61	5	26	crisis	crisis	NOUN
8623hx14s61	5	27	threatening	threaten	VERB
8623hx14s61	5	28	to	to	PART
8623hx14s61	5	29	take	take	VERB
8623hx14s61	5	30	us	we	PRON
8623hx14s61	5	31	back	back	ADV
8623hx14s61	5	32	to	to	ADP
8623hx14s61	5	33	the	the	DET
8623hx14s61	5	34	pre	pre	ADJ
8623hx14s61	5	35	-	-	ADJ
8623hx14s61	5	36	antibiotic	antibiotic	ADJ
8623hx14s61	5	37	days	day	NOUN
8623hx14s61	5	38	.	.	PUNCT
8623hx14s61	6	1	the	the	DET
8623hx14s61	6	2	rapid	rapid	ADJ
8623hx14s61	6	3	rise	rise	NOUN
8623hx14s61	6	4	of	of	ADP
8623hx14s61	6	5	antibiotic	antibiotic	ADJ
8623hx14s61	6	6	resistance	resistance	NOUN
8623hx14s61	6	7	coupled	couple	VERB
8623hx14s61	6	8	with	with	ADP
8623hx14s61	6	9	the	the	DET
8623hx14s61	6	10	lack	lack	NOUN
8623hx14s61	6	11	of	of	ADP
8623hx14s61	6	12	novel	novel	ADJ
8623hx14s61	6	13	antibiotics	antibiotic	NOUN
8623hx14s61	6	14	is	be	AUX
8623hx14s61	6	15	therefore	therefore	ADV
8623hx14s61	6	16	an	an	DET
8623hx14s61	6	17	immediate	immediate	ADJ
8623hx14s61	6	18	health	health	NOUN
8623hx14s61	6	19	concern	concern	NOUN
8623hx14s61	6	20	.	.	PUNCT
8623hx14s61	7	1	β	β	X
8623hx14s61	7	2	-	-	PUNCT
8623hx14s61	7	3	lactams	lactam	NOUN
8623hx14s61	7	4	are	be	AUX
8623hx14s61	7	5	a	a	DET
8623hx14s61	7	6	class	class	NOUN
8623hx14s61	7	7	of	of	ADP
8623hx14s61	7	8	antibiotics	antibiotic	NOUN
8623hx14s61	7	9	often	often	ADV
8623hx14s61	7	10	referred	refer	VERB
8623hx14s61	7	11	to	to	ADP
8623hx14s61	7	12	as	as	ADV
8623hx14s61	7	13	broad	broad	ADJ
8623hx14s61	7	14	-	-	PUNCT
8623hx14s61	7	15	spectrum	spectrum	NOUN
8623hx14s61	7	16	drugs	drug	NOUN
8623hx14s61	7	17	because	because	SCONJ
8623hx14s61	7	18	of	of	ADP
8623hx14s61	7	19	their	their	PRON
8623hx14s61	7	20	effectiveness	effectiveness	NOUN
8623hx14s61	7	21	in	in	ADP
8623hx14s61	7	22	treating	treat	VERB
8623hx14s61	7	23	infections	infection	NOUN
8623hx14s61	7	24	from	from	ADP
8623hx14s61	7	25	multiple	multiple	ADJ
8623hx14s61	7	26	pathogens	pathogen	NOUN
8623hx14s61	7	27	.	.	PUNCT
8623hx14s61	8	1	the	the	DET
8623hx14s61	8	2	mechanism	mechanism	NOUN
8623hx14s61	8	3	of	of	ADP
8623hx14s61	8	4	action	action	NOUN
8623hx14s61	8	5	of	of	ADP
8623hx14s61	8	6	these	these	DET
8623hx14s61	8	7	drugs	drug	NOUN
8623hx14s61	8	8	is	be	AUX
8623hx14s61	8	9	to	to	PART
8623hx14s61	8	10	inhibit	inhibit	VERB
8623hx14s61	8	11	penicillin	penicillin	NOUN
8623hx14s61	8	12	binding	bind	VERB
8623hx14s61	8	13	proteins	protein	NOUN
8623hx14s61	8	14	(	(	PUNCT
8623hx14s61	8	15	pbps	pbps	X
8623hx14s61	8	16	)	)	PUNCT
8623hx14s61	8	17	,	,	PUNCT
8623hx14s61	8	18	which	which	PRON
8623hx14s61	8	19	are	be	AUX
8623hx14s61	8	20	necessary	necessary	ADJ
8623hx14s61	8	21	for	for	ADP
8623hx14s61	8	22	bacterial	bacterial	ADJ
8623hx14s61	8	23	cell	cell	NOUN
8623hx14s61	8	24	wall	wall	PROPN
8623hx14s61	8	25	synthesis	synthesis	PROPN
8623hx14s61	8	26	.	.	PUNCT
8623hx14s61	9	1	antibiotic	antibiotic	ADJ
8623hx14s61	9	2	resistance	resistance	NOUN
8623hx14s61	9	3	towards	towards	ADP
8623hx14s61	9	4	β	β	PROPN
8623hx14s61	9	5	-	-	PUNCT
8623hx14s61	9	6	lactams	lactam	NOUN
8623hx14s61	9	7	is	be	AUX
8623hx14s61	9	8	often	often	ADV
8623hx14s61	9	9	promoted	promote	VERB
8623hx14s61	9	10	via	via	ADP
8623hx14s61	9	11	the	the	DET
8623hx14s61	9	12	production	production	NOUN
8623hx14s61	9	13	of	of	ADP
8623hx14s61	9	14	β	β	NOUN
8623hx14s61	9	15	-	-	PUNCT
8623hx14s61	9	16	lactamases	lactamases	PROPN
8623hx14s61	9	17	that	that	PRON
8623hx14s61	9	18	have	have	VERB
8623hx14s61	9	19	the	the	DET
8623hx14s61	9	20	capability	capability	NOUN
8623hx14s61	9	21	to	to	PART
8623hx14s61	9	22	hydrolyze	hydrolyze	VERB
8623hx14s61	9	23	the	the	DET
8623hx14s61	9	24	β	β	PROPN
8623hx14s61	9	25	-	-	PUNCT
8623hx14s61	9	26	lactams	lactams	NOUN
8623hx14s61	9	27	,	,	PUNCT
8623hx14s61	9	28	rendering	render	VERB
8623hx14s61	9	29	them	they	PRON
8623hx14s61	9	30	ineffective	ineffective	ADJ
8623hx14s61	9	31	against	against	ADP
8623hx14s61	9	32	their	their	PRON
8623hx14s61	9	33	drug	drug	NOUN
8623hx14s61	9	34	targets	target	NOUN
8623hx14s61	9	35	.	.	PUNCT
8623hx14s61	10	1	the	the	DET
8623hx14s61	10	2	focus	focus	NOUN
8623hx14s61	10	3	of	of	ADP
8623hx14s61	10	4	the	the	DET
8623hx14s61	10	5	research	research	NOUN
8623hx14s61	10	6	in	in	ADP
8623hx14s61	10	7	this	this	DET
8623hx14s61	10	8	thesis	thesis	NOUN
8623hx14s61	10	9	is	be	AUX
8623hx14s61	10	10	to	to	PART
8623hx14s61	10	11	further	further	VERB
8623hx14s61	10	12	our	our	PRON
8623hx14s61	10	13	understanding	understanding	NOUN
8623hx14s61	10	14	of	of	ADP
8623hx14s61	10	15	how	how	SCONJ
8623hx14s61	10	16	β	β	NOUN
8623hx14s61	10	17	-	-	PUNCT
8623hx14s61	10	18	lactamases	lactamases	PROPN
8623hx14s61	10	19	are	be	AUX
8623hx14s61	10	20	evolving	evolve	VERB
8623hx14s61	10	21	to	to	PART
8623hx14s61	10	22	provide	provide	VERB
8623hx14s61	10	23	resistance	resistance	NOUN
8623hx14s61	10	24	to	to	ADP
8623hx14s61	10	25	β	β	PROPN
8623hx14s61	10	26	-	-	NOUN
8623hx14s61	10	27	lactams	lactams	NOUN
8623hx14s61	10	28	,	,	PUNCT
8623hx14s61	10	29	with	with	ADP
8623hx14s61	10	30	a	a	DET
8623hx14s61	10	31	specific	specific	ADJ
8623hx14s61	10	32	focus	focus	NOUN
8623hx14s61	10	33	on	on	ADP
8623hx14s61	10	34	resistance	resistance	NOUN
8623hx14s61	10	35	towards	towards	ADP
8623hx14s61	10	36	carbapenems	carbapenem	NOUN
8623hx14s61	10	37	or	or	CCONJ
8623hx14s61	10	38	"	"	PUNCT
8623hx14s61	10	39	drugs	drug	NOUN
8623hx14s61	10	40	of	of	ADP
8623hx14s61	10	41	last	last	ADJ
8623hx14s61	10	42	resort".x	resort".x	SPACE
8623hx14s61	10	43	-	-	PUNCT
8623hx14s61	10	44	ray	ray	NOUN
8623hx14s61	10	45	crystallography	crystallography	NOUN
8623hx14s61	10	46	studies	study	NOUN
8623hx14s61	10	47	have	have	AUX
8623hx14s61	10	48	been	be	AUX
8623hx14s61	10	49	of	of	ADP
8623hx14s61	10	50	utmost	utmost	ADJ
8623hx14s61	10	51	importance	importance	NOUN
8623hx14s61	10	52	in	in	ADP
8623hx14s61	10	53	unraveling	unravel	VERB
8623hx14s61	10	54	how	how	SCONJ
8623hx14s61	10	55	β	β	NOUN
8623hx14s61	10	56	-	-	PUNCT
8623hx14s61	10	57	lactamases	lactamases	PROPN
8623hx14s61	10	58	hydrolyze	hydrolyze	VERB
8623hx14s61	10	59	β	β	PROPN
8623hx14s61	10	60	-	-	PUNCT
8623hx14s61	10	61	lactam	lactam	NOUN
8623hx14s61	10	62	substrates	substrate	NOUN
8623hx14s61	10	63	.	.	PUNCT
8623hx14s61	11	1	the	the	DET
8623hx14s61	11	2	work	work	NOUN
8623hx14s61	11	3	in	in	ADP
8623hx14s61	11	4	this	this	DET
8623hx14s61	11	5	thesis	thesis	NOUN
8623hx14s61	11	6	compliments	compliment	VERB
8623hx14s61	11	7	the	the	DET
8623hx14s61	11	8	static	static	ADJ
8623hx14s61	11	9	view	view	NOUN
8623hx14s61	11	10	of	of	ADP
8623hx14s61	11	11	β	β	NOUN
8623hx14s61	11	12	-	-	PUNCT
8623hx14s61	11	13	lactamases	lactamases	PROPN
8623hx14s61	11	14	given	give	VERB
8623hx14s61	11	15	by	by	ADP
8623hx14s61	11	16	x	x	NOUN
8623hx14s61	11	17	-	-	NOUN
8623hx14s61	11	18	ray	ray	NOUN
8623hx14s61	11	19	crystallography	crystallography	NOUN
8623hx14s61	11	20	with	with	ADP
8623hx14s61	11	21	a	a	DET
8623hx14s61	11	22	dynamic	dynamic	ADJ
8623hx14s61	11	23	perspective	perspective	NOUN
8623hx14s61	11	24	of	of	ADP
8623hx14s61	11	25	β	β	PROPN
8623hx14s61	11	26	-	-	PUNCT
8623hx14s61	11	27	lactamase	lactamase	NOUN
8623hx14s61	11	28	activity	activity	NOUN
8623hx14s61	11	29	given	give	VERB
8623hx14s61	11	30	by	by	ADP
8623hx14s61	11	31	the	the	DET
8623hx14s61	11	32	nuclear	nuclear	ADJ
8623hx14s61	11	33	magnetic	magnetic	ADJ
8623hx14s61	11	34	resonance	resonance	NOUN
8623hx14s61	11	35	(	(	PUNCT
8623hx14s61	11	36	nmr	nmr	NOUN
8623hx14s61	11	37	)	)	PUNCT
8623hx14s61	11	38	studies	study	NOUN
8623hx14s61	11	39	presented	present	VERB
8623hx14s61	11	40	here	here	ADV
8623hx14s61	11	41	.	.	PUNCT
8623hx14s61	12	1	nmr	nmr	PROPN
8623hx14s61	12	2	is	be	AUX
8623hx14s61	12	3	well	well	ADV
8623hx14s61	12	4	-	-	PUNCT
8623hx14s61	12	5	suited	suited	ADJ
8623hx14s61	12	6	for	for	ADP
8623hx14s61	12	7	the	the	DET
8623hx14s61	12	8	study	study	NOUN
8623hx14s61	12	9	of	of	ADP
8623hx14s61	12	10	β	β	PROPN
8623hx14s61	12	11	-	-	PUNCT
8623hx14s61	12	12	lactamase	lactamase	NOUN
8623hx14s61	12	13	activity	activity	NOUN
8623hx14s61	12	14	because	because	SCONJ
8623hx14s61	12	15	it	it	PRON
8623hx14s61	12	16	is	be	AUX
8623hx14s61	12	17	a	a	DET
8623hx14s61	12	18	non	non	ADJ
8623hx14s61	12	19	-	-	ADJ
8623hx14s61	12	20	invasive	invasive	ADJ
8623hx14s61	12	21	technique	technique	NOUN
8623hx14s61	12	22	,	,	PUNCT
8623hx14s61	12	23	reveals	reveal	VERB
8623hx14s61	12	24	site	site	NOUN
8623hx14s61	12	25	-	-	PUNCT
8623hx14s61	12	26	specific	specific	ADJ
8623hx14s61	12	27	structural	structural	ADJ
8623hx14s61	12	28	and	and	CCONJ
8623hx14s61	12	29	dynamics	dynamic	NOUN
8623hx14s61	12	30	information	information	NOUN
8623hx14s61	12	31	,	,	PUNCT
8623hx14s61	12	32	and	and	CCONJ
8623hx14s61	12	33	it	it	PRON
8623hx14s61	12	34	can	can	AUX
8623hx14s61	12	35	be	be	AUX
8623hx14s61	12	36	utilized	utilize	VERB
8623hx14s61	12	37	to	to	PART
8623hx14s61	12	38	study	study	VERB
8623hx14s61	12	39	both	both	CCONJ
8623hx14s61	12	40	the	the	DET
8623hx14s61	12	41	enzyme	enzyme	NOUN
8623hx14s61	12	42	and	and	CCONJ
8623hx14s61	12	43	substrate	substrate	NOUN
8623hx14s61	12	44	.	.	PUNCT
8623hx14s61	13	1	by	by	ADP
8623hx14s61	13	2	understanding	understand	VERB
8623hx14s61	13	3	the	the	DET
8623hx14s61	13	4	conformational	conformational	ADJ
8623hx14s61	13	5	dynamics	dynamic	NOUN
8623hx14s61	13	6	of	of	ADP
8623hx14s61	13	7	β	β	NOUN
8623hx14s61	13	8	-	-	PUNCT
8623hx14s61	13	9	lactamases	lactamases	PROPN
8623hx14s61	13	10	,	,	PUNCT
8623hx14s61	13	11	we	we	PRON
8623hx14s61	13	12	can	can	AUX
8623hx14s61	13	13	potentially	potentially	ADV
8623hx14s61	13	14	design	design	VERB
8623hx14s61	13	15	novel	novel	NOUN
8623hx14s61	13	16	,	,	PUNCT
8623hx14s61	13	17	potent	potent	ADJ
8623hx14s61	13	18	inhibitors	inhibitor	NOUN
8623hx14s61	13	19	to	to	PART
8623hx14s61	13	20	combat	combat	VERB
8623hx14s61	13	21	antibiotic	antibiotic	ADJ
8623hx14s61	13	22	resistance	resistance	NOUN
8623hx14s61	13	23	.	.	PUNCT