id	sid	tid	token	lemma	pos
cr56n012p1v	1	1	cancer	cancer	NOUN
cr56n012p1v	1	2	metastasis	metastasis	NOUN
cr56n012p1v	1	3	alters	alter	VERB
cr56n012p1v	1	4	many	many	ADJ
cr56n012p1v	1	5	of	of	ADP
cr56n012p1v	1	6	the	the	DET
cr56n012p1v	1	7	processes	process	NOUN
cr56n012p1v	1	8	that	that	PRON
cr56n012p1v	1	9	are	be	AUX
cr56n012p1v	1	10	necessary	necessary	ADJ
cr56n012p1v	1	11	for	for	SCONJ
cr56n012p1v	1	12	tumorigenesis	tumorigenesis	NOUN
cr56n012p1v	1	13	to	to	PART
cr56n012p1v	1	14	facilitate	facilitate	VERB
cr56n012p1v	1	15	successful	successful	ADJ
cr56n012p1v	1	16	metastases.however	metastases.however	PROPN
cr56n012p1v	1	17	,	,	PUNCT
cr56n012p1v	1	18	a	a	DET
cr56n012p1v	1	19	global	global	ADJ
cr56n012p1v	1	20	analysis	analysis	NOUN
cr56n012p1v	1	21	of	of	ADP
cr56n012p1v	1	22	the	the	DET
cr56n012p1v	1	23	transcriptome	transcriptome	ADJ
cr56n012p1v	1	24	landscape	landscape	NOUN
cr56n012p1v	1	25	of	of	ADP
cr56n012p1v	1	26	the	the	DET
cr56n012p1v	1	27	metastatic	metastatic	ADJ
cr56n012p1v	1	28	tumor	tumor	NOUN
cr56n012p1v	1	29	has	have	AUX
cr56n012p1v	1	30	not	not	PART
cr56n012p1v	1	31	been	be	AUX
cr56n012p1v	1	32	well	well	ADV
cr56n012p1v	1	33	studied.in	studied.in	NUM
cr56n012p1v	1	34	my	my	PRON
cr56n012p1v	1	35	analysis	analysis	NOUN
cr56n012p1v	1	36	,	,	PUNCT
cr56n012p1v	1	37	i	i	PRON
cr56n012p1v	1	38	compared	compare	VERB
cr56n012p1v	1	39	the	the	DET
cr56n012p1v	1	40	primary	primary	ADJ
cr56n012p1v	1	41	tumor	tumor	NOUN
cr56n012p1v	1	42	to	to	ADP
cr56n012p1v	1	43	the	the	DET
cr56n012p1v	1	44	brain	brain	NOUN
cr56n012p1v	1	45	metastatic	metastatic	ADJ
cr56n012p1v	1	46	tumor	tumor	NOUN
cr56n012p1v	1	47	to	to	PART
cr56n012p1v	1	48	identify	identify	VERB
cr56n012p1v	1	49	the	the	DET
cr56n012p1v	1	50	occurring	occur	VERB
cr56n012p1v	1	51	functional	functional	ADJ
cr56n012p1v	1	52	transcriptome	transcriptome	NOUN
cr56n012p1v	1	53	changes.i	changes.i	NOUN
cr56n012p1v	1	54	further	far	ADV
cr56n012p1v	1	55	identified	identify	VERB
cr56n012p1v	1	56	the	the	DET
cr56n012p1v	1	57	changes	change	NOUN
cr56n012p1v	1	58	that	that	PRON
cr56n012p1v	1	59	are	be	AUX
cr56n012p1v	1	60	unique	unique	ADJ
cr56n012p1v	1	61	to	to	ADP
cr56n012p1v	1	62	the	the	DET
cr56n012p1v	1	63	brain	brain	NOUN
cr56n012p1v	1	64	metastatic	metastatic	ADJ
cr56n012p1v	1	65	process	process	NOUN
cr56n012p1v	1	66	.	.	PUNCT
cr56n012p1v	2	1	i	i	PRON
cr56n012p1v	2	2	finally	finally	ADV
cr56n012p1v	2	3	analyzed	analyze	VERB
cr56n012p1v	2	4	the	the	DET
cr56n012p1v	2	5	gene	gene	NOUN
cr56n012p1v	2	6	expression	expression	NOUN
cr56n012p1v	2	7	pattern	pattern	NOUN
cr56n012p1v	2	8	that	that	PRON
cr56n012p1v	2	9	occurs	occur	VERB
cr56n012p1v	2	10	between	between	ADP
cr56n012p1v	2	11	the	the	DET
cr56n012p1v	2	12	colonization	colonization	NOUN
cr56n012p1v	2	13	stage	stage	NOUN
cr56n012p1v	2	14	and	and	CCONJ
cr56n012p1v	2	15	outgrowth	outgrowth	NOUN
cr56n012p1v	2	16	metastatic	metastatic	ADJ
cr56n012p1v	2	17	stage.this	stage.thi	NOUN
cr56n012p1v	2	18	analysis	analysis	NOUN
cr56n012p1v	2	19	provides	provide	VERB
cr56n012p1v	2	20	a	a	DET
cr56n012p1v	2	21	global	global	ADJ
cr56n012p1v	2	22	view	view	NOUN
cr56n012p1v	2	23	of	of	ADP
cr56n012p1v	2	24	the	the	DET
cr56n012p1v	2	25	brain	brain	NOUN
cr56n012p1v	2	26	metastatic	metastatic	ADJ
cr56n012p1v	2	27	process	process	NOUN
cr56n012p1v	2	28	starting	start	VERB
cr56n012p1v	2	29	from	from	ADP
cr56n012p1v	2	30	the	the	DET
cr56n012p1v	2	31	primary	primary	ADJ
cr56n012p1v	2	32	tumor	tumor	NOUN
cr56n012p1v	2	33	to	to	ADP
cr56n012p1v	2	34	early	early	ADJ
cr56n012p1v	2	35	colonization	colonization	NOUN
cr56n012p1v	2	36	stage	stage	NOUN
cr56n012p1v	2	37	and	and	CCONJ
cr56n012p1v	2	38	finally	finally	ADV
cr56n012p1v	2	39	to	to	ADP
cr56n012p1v	2	40	the	the	DET
cr56n012p1v	2	41	overt	overt	ADJ
cr56n012p1v	2	42	late	late	ADJ
cr56n012p1v	2	43	stage	stage	NOUN
cr56n012p1v	2	44	brain	brain	NOUN
cr56n012p1v	2	45	metastatic	metastatic	NOUN
cr56n012p1v	2	46	tumor.in	tumor.in	NUM
cr56n012p1v	2	47	conjunction	conjunction	NOUN
cr56n012p1v	2	48	with	with	ADP
cr56n012p1v	2	49	the	the	DET
cr56n012p1v	2	50	analysis	analysis	NOUN
cr56n012p1v	2	51	of	of	ADP
cr56n012p1v	2	52	the	the	DET
cr56n012p1v	2	53	metastatic	metastatic	ADJ
cr56n012p1v	2	54	tumor	tumor	NOUN
cr56n012p1v	2	55	,	,	PUNCT
cr56n012p1v	2	56	i	i	PRON
cr56n012p1v	2	57	also	also	ADV
cr56n012p1v	2	58	conducted	conduct	VERB
cr56n012p1v	2	59	a	a	DET
cr56n012p1v	2	60	global	global	ADJ
cr56n012p1v	2	61	analysis	analysis	NOUN
cr56n012p1v	2	62	of	of	ADP
cr56n012p1v	2	63	the	the	DET
cr56n012p1v	2	64	surrounding	surround	VERB
cr56n012p1v	2	65	microenvironment.i	microenvironment.i	PROPN
cr56n012p1v	2	66	first	first	ADV
cr56n012p1v	2	67	compared	compare	VERB
cr56n012p1v	2	68	the	the	DET
cr56n012p1v	2	69	primary	primary	ADJ
cr56n012p1v	2	70	tumor	tumor	NOUN
cr56n012p1v	2	71	and	and	CCONJ
cr56n012p1v	2	72	brain	brain	NOUN
cr56n012p1v	2	73	metastatic	metastatic	ADJ
cr56n012p1v	2	74	microenvironments	microenvironment	NOUN
cr56n012p1v	2	75	for	for	ADP
cr56n012p1v	2	76	their	their	PRON
cr56n012p1v	2	77	respective	respective	ADJ
cr56n012p1v	2	78	gene	gene	NOUN
cr56n012p1v	2	79	expression	expression	NOUN
cr56n012p1v	2	80	changes.furthermore	changes.furthermore	ADV
cr56n012p1v	2	81	,	,	PUNCT
cr56n012p1v	2	82	i	i	PRON
cr56n012p1v	2	83	compared	compare	VERB
cr56n012p1v	2	84	the	the	DET
cr56n012p1v	2	85	surrounding	surround	VERB
cr56n012p1v	2	86	microenvironment	microenvironment	NOUN
cr56n012p1v	2	87	during	during	ADP
cr56n012p1v	2	88	the	the	DET
cr56n012p1v	2	89	early	early	ADJ
cr56n012p1v	2	90	and	and	CCONJ
cr56n012p1v	2	91	late	late	ADJ
cr56n012p1v	2	92	stages	stage	NOUN
cr56n012p1v	2	93	of	of	ADP
cr56n012p1v	2	94	brain	brain	NOUN
cr56n012p1v	2	95	metastases.this	metastases.this	PRON
cr56n012p1v	2	96	global	global	ADJ
cr56n012p1v	2	97	analysis	analysis	NOUN
cr56n012p1v	2	98	provides	provide	VERB
cr56n012p1v	2	99	one	one	NUM
cr56n012p1v	2	100	of	of	ADP
cr56n012p1v	2	101	the	the	DET
cr56n012p1v	2	102	first	first	ADJ
cr56n012p1v	2	103	global	global	ADJ
cr56n012p1v	2	104	views	view	NOUN
cr56n012p1v	2	105	of	of	ADP
cr56n012p1v	2	106	the	the	DET
cr56n012p1v	2	107	transcriptome	transcriptome	ADJ
cr56n012p1v	2	108	landscape	landscape	NOUN
cr56n012p1v	2	109	of	of	ADP
cr56n012p1v	2	110	the	the	DET
cr56n012p1v	2	111	brain	brain	NOUN
cr56n012p1v	2	112	microenvironment	microenvironment	NOUN
cr56n012p1v	2	113	during	during	ADP
cr56n012p1v	2	114	the	the	DET
cr56n012p1v	2	115	entire	entire	ADJ
cr56n012p1v	2	116	metastatic	metastatic	ADJ
cr56n012p1v	2	117	process.my	process.my	X
cr56n012p1v	2	118	global	global	ADJ
cr56n012p1v	2	119	analysis	analysis	NOUN
cr56n012p1v	2	120	of	of	ADP
cr56n012p1v	2	121	both	both	CCONJ
cr56n012p1v	2	122	the	the	DET
cr56n012p1v	2	123	tumor	tumor	NOUN
cr56n012p1v	2	124	and	and	CCONJ
cr56n012p1v	2	125	stroma	stroma	NOUN
cr56n012p1v	2	126	provide	provide	VERB
cr56n012p1v	2	127	insights	insight	NOUN
cr56n012p1v	2	128	into	into	ADP
cr56n012p1v	2	129	many	many	ADJ
cr56n012p1v	2	130	aspects	aspect	NOUN
cr56n012p1v	2	131	of	of	ADP
cr56n012p1v	2	132	the	the	DET
cr56n012p1v	2	133	metastatic	metastatic	NOUN
cr56n012p1v	2	134	process.to	process.to	X
cr56n012p1v	2	135	further	far	ADV
cr56n012p1v	2	136	investigate	investigate	VERB
cr56n012p1v	2	137	these	these	DET
cr56n012p1v	2	138	insights	insight	NOUN
cr56n012p1v	2	139	,	,	PUNCT
cr56n012p1v	2	140	i	i	PRON
cr56n012p1v	2	141	focused	focus	VERB
cr56n012p1v	2	142	on	on	ADP
cr56n012p1v	2	143	the	the	DET
cr56n012p1v	2	144	role	role	NOUN
cr56n012p1v	2	145	of	of	ADP
cr56n012p1v	2	146	metabolism	metabolism	NOUN
cr56n012p1v	2	147	in	in	ADP
cr56n012p1v	2	148	the	the	DET
cr56n012p1v	2	149	brain	brain	NOUN
cr56n012p1v	2	150	metastatic	metastatic	NOUN
cr56n012p1v	2	151	process.based	process.base	VERB
cr56n012p1v	2	152	on	on	ADP
cr56n012p1v	2	153	a	a	DET
cr56n012p1v	2	154	distinct	distinct	ADJ
cr56n012p1v	2	155	metabolic	metabolic	NOUN
cr56n012p1v	2	156	transcriptome	transcriptome	NOUN
cr56n012p1v	2	157	profile	profile	NOUN
cr56n012p1v	2	158	in	in	ADP
cr56n012p1v	2	159	brain	brain	NOUN
cr56n012p1v	2	160	metastases	metastasis	NOUN
cr56n012p1v	2	161	compared	compare	VERB
cr56n012p1v	2	162	to	to	ADP
cr56n012p1v	2	163	their	their	PRON
cr56n012p1v	2	164	primary	primary	ADJ
cr56n012p1v	2	165	tumor	tumor	NOUN
cr56n012p1v	2	166	counterparts	counterpart	NOUN
cr56n012p1v	2	167	,	,	PUNCT
cr56n012p1v	2	168	i	i	PRON
cr56n012p1v	2	169	hypothesized	hypothesize	VERB
cr56n012p1v	2	170	that	that	SCONJ
cr56n012p1v	2	171	metabolic	metabolic	NOUN
cr56n012p1v	2	172	transcriptome	transcriptome	NOUN
cr56n012p1v	2	173	shifting	shift	VERB
cr56n012p1v	2	174	during	during	ADP
cr56n012p1v	2	175	metastatic	metastatic	ADJ
cr56n012p1v	2	176	evolution	evolution	NOUN
cr56n012p1v	2	177	is	be	AUX
cr56n012p1v	2	178	crucial	crucial	ADJ
cr56n012p1v	2	179	for	for	ADP
cr56n012p1v	2	180	metastatic	metastatic	ADJ
cr56n012p1v	2	181	success	success	NOUN
cr56n012p1v	2	182	to	to	ADP
cr56n012p1v	2	183	the	the	DET
cr56n012p1v	2	184	brain	brain	NOUN
cr56n012p1v	2	185	.	.	PUNCT
cr56n012p1v	3	1	here	here	ADV
cr56n012p1v	3	2	i	i	PRON
cr56n012p1v	3	3	show	show	VERB
cr56n012p1v	3	4	that	that	SCONJ
cr56n012p1v	3	5	the	the	DET
cr56n012p1v	3	6	expression	expression	NOUN
cr56n012p1v	3	7	of	of	ADP
cr56n012p1v	3	8	the	the	DET
cr56n012p1v	3	9	gaba	gaba	NOUN
cr56n012p1v	3	10	metabolic	metabolic	NOUN
cr56n012p1v	3	11	pathway	pathway	NOUN
cr56n012p1v	3	12	mediator	mediator	NOUN
cr56n012p1v	3	13	glutamate	glutamate	NOUN
cr56n012p1v	3	14	decarboxylase	decarboxylase	NOUN
cr56n012p1v	3	15	1	1	NUM
cr56n012p1v	3	16	(	(	PUNCT
cr56n012p1v	3	17	gad1	gad1	NOUN
cr56n012p1v	3	18	)	)	PUNCT
cr56n012p1v	3	19	is	be	AUX
cr56n012p1v	3	20	significantly	significantly	ADV
cr56n012p1v	3	21	up	up	ADV
cr56n012p1v	3	22	-	-	PUNCT
cr56n012p1v	3	23	regulated	regulate	VERB
cr56n012p1v	3	24	.	.	PUNCT
cr56n012p1v	4	1	down	down	ADP
cr56n012p1v	4	2	-	-	PUNCT
cr56n012p1v	4	3	regulation	regulation	NOUN
cr56n012p1v	4	4	of	of	ADP
cr56n012p1v	4	5	dna	dna	PROPN
cr56n012p1v	4	6	methyltransferase	methyltransferase	NOUN
cr56n012p1v	4	7	1	1	NUM
cr56n012p1v	4	8	(	(	PUNCT
cr56n012p1v	4	9	dnmt1	dnmt1	PROPN
cr56n012p1v	4	10	)	)	PUNCT
cr56n012p1v	4	11	induced	induce	VERB
cr56n012p1v	4	12	by	by	ADP
cr56n012p1v	4	13	the	the	DET
cr56n012p1v	4	14	brain	brain	NOUN
cr56n012p1v	4	15	microenvironment	microenvironment	NOUN
cr56n012p1v	4	16	results	result	NOUN
cr56n012p1v	4	17	in	in	ADP
cr56n012p1v	4	18	decreased	decrease	VERB
cr56n012p1v	4	19	gad1	gad1	NOUN
cr56n012p1v	4	20	promoter	promoter	NOUN
cr56n012p1v	4	21	methylation	methylation	NOUN
cr56n012p1v	4	22	and	and	CCONJ
cr56n012p1v	4	23	subsequent	subsequent	ADJ
cr56n012p1v	4	24	up	up	NOUN
cr56n012p1v	4	25	-	-	PUNCT
cr56n012p1v	4	26	regulation	regulation	NOUN
cr56n012p1v	4	27	of	of	ADP
cr56n012p1v	4	28	gad1	gad1	ADJ
cr56n012p1v	4	29	expression	expression	NOUN
cr56n012p1v	4	30	.	.	PUNCT
cr56n012p1v	5	1	i	i	PRON
cr56n012p1v	5	2	utilized	utilize	VERB
cr56n012p1v	5	3	the	the	DET
cr56n012p1v	5	4	peredox	peredox	NOUN
cr56n012p1v	5	5	biosensor	biosensor	NOUN
cr56n012p1v	5	6	coupled	couple	VERB
cr56n012p1v	5	7	with	with	ADP
cr56n012p1v	5	8	time	time	NOUN
cr56n012p1v	5	9	-	-	PUNCT
cr56n012p1v	5	10	lapse	lapse	NOUN
cr56n012p1v	5	11	imaging	imaging	NOUN
cr56n012p1v	5	12	to	to	PART
cr56n012p1v	5	13	monitor	monitor	VERB
cr56n012p1v	5	14	the	the	DET
cr56n012p1v	5	15	cytosolic	cytosolic	NOUN
cr56n012p1v	5	16	nadh	nadh	NOUN
cr56n012p1v	5	17	:	:	PUNCT
cr56n012p1v	5	18	nad+	nad+	PROPN
cr56n012p1v	5	19	equilibrium	equilibrium	NOUN
cr56n012p1v	5	20	in	in	ADP
cr56n012p1v	5	21	tumor	tumor	NOUN
cr56n012p1v	5	22	cells	cell	NOUN
cr56n012p1v	5	23	.	.	PUNCT
cr56n012p1v	6	1	knocking	knock	VERB
cr56n012p1v	6	2	down	down	ADP
cr56n012p1v	6	3	of	of	ADP
cr56n012p1v	6	4	gad1	gad1	PROPN
cr56n012p1v	6	5	abolishes	abolish	VERB
cr56n012p1v	6	6	the	the	DET
cr56n012p1v	6	7	capability	capability	NOUN
cr56n012p1v	6	8	of	of	ADP
cr56n012p1v	6	9	tumor	tumor	NOUN
cr56n012p1v	6	10	cells	cell	NOUN
cr56n012p1v	6	11	to	to	PART
cr56n012p1v	6	12	utilize	utilize	VERB
cr56n012p1v	6	13	extracellular	extracellular	ADJ
cr56n012p1v	6	14	glutamine	glutamine	NOUN
cr56n012p1v	6	15	.	.	PUNCT
cr56n012p1v	7	1	repurposing	repurpose	VERB
cr56n012p1v	7	2	of	of	ADP
cr56n012p1v	7	3	a	a	DET
cr56n012p1v	7	4	neurological	neurological	ADJ
cr56n012p1v	7	5	drug	drug	NOUN
cr56n012p1v	7	6	,	,	PUNCT
cr56n012p1v	7	7	vigabatrin	vigabatrin	NOUN
cr56n012p1v	7	8	,	,	PUNCT
cr56n012p1v	7	9	results	result	VERB
cr56n012p1v	7	10	in	in	ADP
cr56n012p1v	7	11	a	a	DET
cr56n012p1v	7	12	significant	significant	ADJ
cr56n012p1v	7	13	decrease	decrease	NOUN
cr56n012p1v	7	14	in	in	ADP
cr56n012p1v	7	15	brain	brain	NOUN
cr56n012p1v	7	16	metastasis	metastasis	NOUN
cr56n012p1v	7	17	incidence	incidence	NOUN
cr56n012p1v	7	18	.	.	PUNCT
cr56n012p1v	8	1	taken	take	VERB
cr56n012p1v	8	2	together	together	ADV
cr56n012p1v	8	3	,	,	PUNCT
cr56n012p1v	8	4	my	my	PRON
cr56n012p1v	8	5	results	result	NOUN
cr56n012p1v	8	6	demonstrated	demonstrate	VERB
cr56n012p1v	8	7	that	that	SCONJ
cr56n012p1v	8	8	brain	brain	NOUN
cr56n012p1v	8	9	microenvironment	microenvironment	NOUN
cr56n012p1v	8	10	-	-	PUNCT
cr56n012p1v	8	11	specific	specific	ADJ
cr56n012p1v	8	12	metabolic	metabolic	NOUN
cr56n012p1v	8	13	shifting	shift	VERB
cr56n012p1v	8	14	through	through	ADP
cr56n012p1v	8	15	gad1	gad1	ADJ
cr56n012p1v	8	16	promoter	promoter	NOUN
cr56n012p1v	8	17	demethylation	demethylation	NOUN
cr56n012p1v	8	18	contributes	contribute	VERB
cr56n012p1v	8	19	to	to	ADP
cr56n012p1v	8	20	the	the	DET
cr56n012p1v	8	21	context	context	NOUN
cr56n012p1v	8	22	-	-	PUNCT
cr56n012p1v	8	23	dependent	dependent	ADJ
cr56n012p1v	8	24	cellular	cellular	ADJ
cr56n012p1v	8	25	metabolic	metabolic	NOUN
cr56n012p1v	8	26	adaption	adaption	NOUN
cr56n012p1v	8	27	and	and	CCONJ
cr56n012p1v	8	28	facilitate	facilitate	VERB
cr56n012p1v	8	29	brain	brain	NOUN
cr56n012p1v	8	30	metastasis	metastasis	NOUN
cr56n012p1v	8	31	outgrowth	outgrowth	NOUN
cr56n012p1v	8	32	.	.	PUNCT