id sid tid token lemma pos f7623b61542 1 1 hydrogen hydrogen PROPN f7623b61542 1 2 sulfide sulfide PROPN f7623b61542 1 3 has have AUX f7623b61542 1 4 in in ADP f7623b61542 1 5 the the DET f7623b61542 1 6 last last ADJ f7623b61542 1 7 15 15 NUM f7623b61542 1 8 years year NOUN f7623b61542 1 9 been be AUX f7623b61542 1 10 elevated elevate VERB f7623b61542 1 11 from from ADP f7623b61542 1 12 its its PRON f7623b61542 1 13 previous previous ADJ f7623b61542 1 14 place place NOUN f7623b61542 1 15 as as ADP f7623b61542 1 16 nothing nothing PRON f7623b61542 1 17 more more ADJ f7623b61542 1 18 than than ADP f7623b61542 1 19 a a DET f7623b61542 1 20 toxic toxic ADJ f7623b61542 1 21 gas gas NOUN f7623b61542 1 22 to to ADP f7623b61542 1 23 the the DET f7623b61542 1 24 status status NOUN f7623b61542 1 25 of of ADP f7623b61542 1 26 ubiquitous ubiquitous ADJ f7623b61542 1 27 gasotransmitter gasotransmitter NOUN f7623b61542 1 28 with with ADP f7623b61542 1 29 numerous numerous ADJ f7623b61542 1 30 physiologic physiologic ADJ f7623b61542 1 31 functions function NOUN f7623b61542 1 32 . . PUNCT f7623b61542 2 1 in in ADP f7623b61542 2 2 this this DET f7623b61542 2 3 thesis thesis NOUN f7623b61542 2 4 the the DET f7623b61542 2 5 focus focus NOUN f7623b61542 2 6 is be AUX f7623b61542 2 7 two two NUM f7623b61542 2 8 - - ADJ f7623b61542 2 9 fold fold ADJ f7623b61542 2 10 : : PUNCT f7623b61542 2 11 whether whether SCONJ f7623b61542 2 12 h2s h2s ADJ f7623b61542 2 13 functions function NOUN f7623b61542 2 14 as as ADP f7623b61542 2 15 a a DET f7623b61542 2 16 gasotransmitter gasotransmitter NOUN f7623b61542 2 17 in in ADP f7623b61542 2 18 blood blood NOUN f7623b61542 2 19 and and CCONJ f7623b61542 2 20 whether whether SCONJ f7623b61542 2 21 h2s h2s NOUN f7623b61542 2 22 could could AUX f7623b61542 2 23 act act VERB f7623b61542 2 24 more more ADV f7623b61542 2 25 locally locally ADV f7623b61542 2 26 as as ADP f7623b61542 2 27 an an DET f7623b61542 2 28 endogenous endogenous ADJ f7623b61542 2 29 oxygen oxygen NOUN f7623b61542 2 30 sensor sensor NOUN f7623b61542 2 31 . . PUNCT f7623b61542 3 1 the the DET f7623b61542 3 2 initial initial ADJ f7623b61542 3 3 research research NOUN f7623b61542 3 4 presented present VERB f7623b61542 3 5 here here ADV f7623b61542 3 6 examines examine VERB f7623b61542 3 7 sulfide sulfide NOUN f7623b61542 3 8 measurement measurement NOUN f7623b61542 3 9 techniques technique NOUN f7623b61542 3 10 for for ADP f7623b61542 3 11 biologic biologic ADJ f7623b61542 3 12 samples sample NOUN f7623b61542 3 13 , , PUNCT f7623b61542 3 14 and and CCONJ f7623b61542 3 15 assessed assess VERB f7623b61542 3 16 their their PRON f7623b61542 3 17 applicability applicability NOUN f7623b61542 3 18 for for ADP f7623b61542 3 19 use use NOUN f7623b61542 3 20 in in ADP f7623b61542 3 21 blood blood NOUN f7623b61542 3 22 and and CCONJ f7623b61542 3 23 plasma plasma NOUN f7623b61542 3 24 . . PUNCT f7623b61542 4 1 it it PRON f7623b61542 4 2 also also ADV f7623b61542 4 3 shows show VERB f7623b61542 4 4 the the DET f7623b61542 4 5 development development NOUN f7623b61542 4 6 of of ADP f7623b61542 4 7 an an DET f7623b61542 4 8 amperometric amperometric NOUN f7623b61542 4 9 means mean NOUN f7623b61542 4 10 of of ADP f7623b61542 4 11 conducting conduct VERB f7623b61542 4 12 this this DET f7623b61542 4 13 research research NOUN f7623b61542 4 14 . . PUNCT f7623b61542 5 1 it it PRON f7623b61542 5 2 was be AUX f7623b61542 5 3 found find VERB f7623b61542 5 4 that that SCONJ f7623b61542 5 5 the the DET f7623b61542 5 6 standard standard ADJ f7623b61542 5 7 protocol protocol NOUN f7623b61542 5 8 for for ADP f7623b61542 5 9 potentiometric potentiometric ADJ f7623b61542 5 10 measurement measurement NOUN f7623b61542 5 11 of of ADP f7623b61542 5 12 sulfide sulfide NOUN f7623b61542 5 13 in in ADP f7623b61542 5 14 plasma plasma NOUN f7623b61542 5 15 is be AUX f7623b61542 5 16 unsuitable unsuitable ADJ f7623b61542 5 17 for for ADP f7623b61542 5 18 such such ADJ f7623b61542 5 19 use use NOUN f7623b61542 5 20 . . PUNCT f7623b61542 6 1 the the DET f7623b61542 6 2 experimental experimental ADJ f7623b61542 6 3 conditions condition NOUN f7623b61542 6 4 liberate liberate VERB f7623b61542 6 5 sulfide sulfide NOUN f7623b61542 6 6 from from ADP f7623b61542 6 7 cysteines cysteine NOUN f7623b61542 6 8 in in ADP f7623b61542 6 9 plasma plasma NOUN f7623b61542 6 10 proteins protein NOUN f7623b61542 6 11 , , PUNCT f7623b61542 6 12 creating create VERB f7623b61542 6 13 artificially artificially ADV f7623b61542 6 14 high high ADJ f7623b61542 6 15 sulfide sulfide NOUN f7623b61542 6 16 measurements measurement NOUN f7623b61542 6 17 . . PUNCT f7623b61542 7 1 using use VERB f7623b61542 7 2 the the DET f7623b61542 7 3 methylene methylene NOUN f7623b61542 7 4 blue blue ADJ f7623b61542 7 5 method method NOUN f7623b61542 7 6 we we PRON f7623b61542 7 7 were be AUX f7623b61542 7 8 unable unable ADJ f7623b61542 7 9 to to PART f7623b61542 7 10 replicate replicate VERB f7623b61542 7 11 blood blood NOUN f7623b61542 7 12 sulfide sulfide NOUN f7623b61542 7 13 measurements measurement NOUN f7623b61542 7 14 found find VERB f7623b61542 7 15 in in ADP f7623b61542 7 16 other other ADJ f7623b61542 7 17 studies study NOUN f7623b61542 7 18 , , PUNCT f7623b61542 7 19 while while SCONJ f7623b61542 7 20 showing show VERB f7623b61542 7 21 unequivocally unequivocally ADV f7623b61542 7 22 that that SCONJ f7623b61542 7 23 this this DET f7623b61542 7 24 method method NOUN f7623b61542 7 25 should should AUX f7623b61542 7 26 work work VERB f7623b61542 7 27 in in ADP f7623b61542 7 28 plasma plasma NOUN f7623b61542 7 29 if if SCONJ f7623b61542 7 30 sulfide sulfide NOUN f7623b61542 7 31 is be AUX f7623b61542 7 32 present present ADJ f7623b61542 7 33 . . PUNCT f7623b61542 8 1 the the DET f7623b61542 8 2 amperometric amperometric ADJ f7623b61542 8 3 sensor sensor NOUN f7623b61542 8 4 developed develop VERB f7623b61542 8 5 here here ADV f7623b61542 8 6 may may AUX f7623b61542 8 7 be be AUX f7623b61542 8 8 used use VERB f7623b61542 8 9 in in ADP f7623b61542 8 10 real real ADJ f7623b61542 8 11 time time NOUN f7623b61542 8 12 without without ADP f7623b61542 8 13 altering alter VERB f7623b61542 8 14 the the DET f7623b61542 8 15 sample sample NOUN f7623b61542 8 16 . . PUNCT f7623b61542 9 1 using use VERB f7623b61542 9 2 this this DET f7623b61542 9 3 method method NOUN f7623b61542 9 4 we we PRON f7623b61542 9 5 showed show VERB f7623b61542 9 6 in in ADP f7623b61542 9 7 blood blood NOUN f7623b61542 9 8 from from ADP f7623b61542 9 9 numerous numerous ADJ f7623b61542 9 10 animals animal NOUN f7623b61542 9 11 that that PRON f7623b61542 9 12 free free ADJ f7623b61542 9 13 h2s h2s NOUN f7623b61542 9 14 is be AUX f7623b61542 9 15 undetectable undetectable ADJ f7623b61542 9 16 in in ADP f7623b61542 9 17 blood blood NOUN f7623b61542 9 18 and and CCONJ f7623b61542 9 19 that that SCONJ f7623b61542 9 20 blood blood NOUN f7623b61542 9 21 consumes consume VERB f7623b61542 9 22 sulfide sulfide NOUN f7623b61542 9 23 quite quite ADV f7623b61542 9 24 rapidly rapidly ADV f7623b61542 9 25 . . PUNCT f7623b61542 10 1 the the DET f7623b61542 10 2 second second ADJ f7623b61542 10 3 portion portion NOUN f7623b61542 10 4 of of ADP f7623b61542 10 5 this this DET f7623b61542 10 6 research research NOUN f7623b61542 10 7 showed show VERB f7623b61542 10 8 that that SCONJ f7623b61542 10 9 tissues tissue NOUN f7623b61542 10 10 consume consume VERB f7623b61542 10 11 endogenously endogenously ADV f7623b61542 10 12 - - PUNCT f7623b61542 10 13 produced produce VERB f7623b61542 10 14 h2s h2s NOUN f7623b61542 10 15 oxygen oxygen NOUN f7623b61542 10 16 - - PUNCT f7623b61542 10 17 dependently dependently ADV f7623b61542 10 18 and and CCONJ f7623b61542 10 19 that that SCONJ f7623b61542 10 20 the the DET f7623b61542 10 21 likely likely ADJ f7623b61542 10 22 location location NOUN f7623b61542 10 23 of of ADP f7623b61542 10 24 this this DET f7623b61542 10 25 consumption consumption NOUN f7623b61542 10 26 is be AUX f7623b61542 10 27 in in ADP f7623b61542 10 28 the the DET f7623b61542 10 29 mitochondria mitochondria PROPN f7623b61542 10 30 . . PUNCT f7623b61542 11 1 the the DET f7623b61542 11 2 inhibitory inhibitory ADJ f7623b61542 11 3 level level NOUN f7623b61542 11 4 of of ADP f7623b61542 11 5 oxygen oxygen NOUN f7623b61542 11 6 was be AUX f7623b61542 11 7 quite quite ADV f7623b61542 11 8 low low ADJ f7623b61542 11 9 , , PUNCT f7623b61542 11 10 and and CCONJ f7623b61542 11 11 the the DET f7623b61542 11 12 levels level NOUN f7623b61542 11 13 of of ADP f7623b61542 11 14 cysteine cysteine NOUN f7623b61542 11 15 required require VERB f7623b61542 11 16 to to PART f7623b61542 11 17 stimulate stimulate VERB f7623b61542 11 18 measurable measurable ADJ f7623b61542 11 19 production production NOUN f7623b61542 11 20 were be AUX f7623b61542 11 21 supraphysiologic supraphysiologic ADJ f7623b61542 11 22 , , PUNCT f7623b61542 11 23 thus thus ADV f7623b61542 11 24 an an DET f7623b61542 11 25 attempt attempt NOUN f7623b61542 11 26 was be AUX f7623b61542 11 27 made make VERB f7623b61542 11 28 to to PART f7623b61542 11 29 develop develop VERB f7623b61542 11 30 a a DET f7623b61542 11 31 means means NOUN f7623b61542 11 32 of of ADP f7623b61542 11 33 measuring measure VERB f7623b61542 11 34 intracellular intracellular ADJ f7623b61542 11 35 sulfide sulfide NOUN f7623b61542 11 36 . . PUNCT f7623b61542 12 1 this this PRON f7623b61542 12 2 was be AUX f7623b61542 12 3 done do VERB f7623b61542 12 4 through through ADP f7623b61542 12 5 sulfide sulfide NOUN f7623b61542 12 6 - - PUNCT f7623b61542 12 7 sensitive sensitive ADJ f7623b61542 12 8 photonic photonic ADJ f7623b61542 12 9 explorers explorer NOUN f7623b61542 12 10 for for ADP f7623b61542 12 11 bioanalysis bioanalysis NOUN f7623b61542 12 12 with with ADP f7623b61542 12 13 biologically biologically ADV f7623b61542 12 14 localized localize VERB f7623b61542 12 15 embedding embed VERB f7623b61542 12 16 ( ( PUNCT f7623b61542 12 17 pebble pebble NOUN f7623b61542 12 18 ) ) PUNCT f7623b61542 12 19 . . PUNCT f7623b61542 13 1 pebbles pebble NOUN f7623b61542 13 2 were be AUX f7623b61542 13 3 produced produce VERB f7623b61542 13 4 in in ADP f7623b61542 13 5 an an DET f7623b61542 13 6 organically organically ADV f7623b61542 13 7 - - PUNCT f7623b61542 13 8 modified modify VERB f7623b61542 13 9 silica silica NOUN f7623b61542 13 10 matrix matrix NOUN f7623b61542 13 11 using use VERB f7623b61542 13 12 the the DET f7623b61542 13 13 sulfide sulfide NOUN f7623b61542 13 14 - - PUNCT f7623b61542 13 15 sensitive sensitive ADJ f7623b61542 13 16 fluorescent fluorescent NOUN f7623b61542 13 17 dye dye NOUN f7623b61542 13 18 fluorescein fluorescein PROPN f7623b61542 13 19 mercuric mercuric PROPN f7623b61542 13 20 acetate acetate PROPN f7623b61542 13 21 . . PUNCT f7623b61542 14 1 while while SCONJ f7623b61542 14 2 the the DET f7623b61542 14 3 pebbles pebble NOUN f7623b61542 14 4 were be AUX f7623b61542 14 5 sensitive sensitive ADJ f7623b61542 14 6 to to PART f7623b61542 14 7 h2s h2s VERB f7623b61542 14 8 and and CCONJ f7623b61542 14 9 insensitive insensitive ADJ f7623b61542 14 10 to to ADP f7623b61542 14 11 cysteine cysteine NOUN f7623b61542 14 12 , , PUNCT f7623b61542 14 13 intracellular intracellular ADJ f7623b61542 14 14 production production NOUN f7623b61542 14 15 of of ADP f7623b61542 14 16 sulfide sulfide NOUN f7623b61542 14 17 was be AUX f7623b61542 14 18 not not PART f7623b61542 14 19 successfully successfully ADV f7623b61542 14 20 demonstrated demonstrate VERB f7623b61542 14 21 . . PUNCT f7623b61542 15 1 h2s h2s NOUN f7623b61542 15 2 may may AUX f7623b61542 15 3 function function VERB f7623b61542 15 4 as as ADP f7623b61542 15 5 an an DET f7623b61542 15 6 oxygen oxygen NOUN f7623b61542 15 7 sensor sensor NOUN f7623b61542 15 8 intracellularly intracellularly ADV f7623b61542 15 9 , , PUNCT f7623b61542 15 10 but but CCONJ f7623b61542 15 11 it it PRON f7623b61542 15 12 does do AUX f7623b61542 15 13 not not PART f7623b61542 15 14 circulate circulate VERB f7623b61542 15 15 in in ADP f7623b61542 15 16 the the DET f7623b61542 15 17 blood blood NOUN f7623b61542 15 18 and and CCONJ f7623b61542 15 19 is be AUX f7623b61542 15 20 unlikely unlikely ADJ f7623b61542 15 21 to to PART f7623b61542 15 22 exist exist VERB f7623b61542 15 23 outside outside ADV f7623b61542 15 24 of of ADP f7623b61542 15 25 localized localize VERB f7623b61542 15 26 pockets pocket NOUN f7623b61542 15 27 within within ADP f7623b61542 15 28 cells cell NOUN f7623b61542 15 29 due due ADJ f7623b61542 15 30 to to ADP f7623b61542 15 31 rapid rapid ADJ f7623b61542 15 32 oxidation oxidation NOUN f7623b61542 15 33 . . PUNCT f7623b61542 16 1 further further ADJ f7623b61542 16 2 work work NOUN f7623b61542 16 3 should should AUX f7623b61542 16 4 be be AUX f7623b61542 16 5 done do VERB f7623b61542 16 6 to to PART f7623b61542 16 7 establish establish VERB f7623b61542 16 8 a a DET f7623b61542 16 9 means means NOUN f7623b61542 16 10 of of ADP f7623b61542 16 11 intracellular intracellular ADJ f7623b61542 16 12 measurement measurement NOUN f7623b61542 16 13 of of ADP f7623b61542 16 14 h2s h2s PROPN f7623b61542 16 15 . . PUNCT