id sid tid token lemma pos hq37vm4346c 1 1 previous previous ADJ hq37vm4346c 1 2 in in ADP hq37vm4346c 1 3 vivo vivo NOUN hq37vm4346c 1 4 and and CCONJ hq37vm4346c 1 5 in in ADP hq37vm4346c 1 6 vitro vitro X hq37vm4346c 1 7 studies study NOUN hq37vm4346c 1 8 have have AUX hq37vm4346c 1 9 suggested suggest VERB hq37vm4346c 1 10 that that SCONJ hq37vm4346c 1 11 vitamin vitamin NOUN hq37vm4346c 1 12 d3 d3 PROPN hq37vm4346c 1 13 may may AUX hq37vm4346c 1 14 have have VERB hq37vm4346c 1 15 chemopreventive chemopreventive ADJ hq37vm4346c 1 16 and and CCONJ hq37vm4346c 1 17 chemotherapeutic chemotherapeutic ADJ hq37vm4346c 1 18 properties property NOUN hq37vm4346c 1 19 in in ADP hq37vm4346c 1 20 the the DET hq37vm4346c 1 21 management management NOUN hq37vm4346c 1 22 and and CCONJ hq37vm4346c 1 23 treatment treatment NOUN hq37vm4346c 1 24 of of ADP hq37vm4346c 1 25 androgen androgen NOUN hq37vm4346c 1 26 - - PUNCT hq37vm4346c 1 27 dependent dependent ADJ hq37vm4346c 1 28 and and CCONJ hq37vm4346c 1 29 androgen androgen NOUN hq37vm4346c 1 30 - - PUNCT hq37vm4346c 1 31 independent independent ADJ hq37vm4346c 1 32 prostate prostate NOUN hq37vm4346c 1 33 cancer cancer NOUN hq37vm4346c 1 34 . . PUNCT hq37vm4346c 2 1 to to PART hq37vm4346c 2 2 investigate investigate VERB hq37vm4346c 2 3 the the DET hq37vm4346c 2 4 therapeutic therapeutic ADJ hq37vm4346c 2 5 potential potential NOUN hq37vm4346c 2 6 of of ADP hq37vm4346c 2 7 vitamin vitamin NOUN hq37vm4346c 2 8 d3 d3 PROPN hq37vm4346c 2 9 for for ADP hq37vm4346c 2 10 prostate prostate NOUN hq37vm4346c 2 11 cancer cancer NOUN hq37vm4346c 2 12 , , PUNCT hq37vm4346c 2 13 we we PRON hq37vm4346c 2 14 have have AUX hq37vm4346c 2 15 utilized utilize VERB hq37vm4346c 2 16 the the DET hq37vm4346c 2 17 lpb lpb PROPN hq37vm4346c 2 18 - - PUNCT hq37vm4346c 2 19 tag tag NOUN hq37vm4346c 2 20 transgenic transgenic NOUN hq37vm4346c 2 21 model model NOUN hq37vm4346c 2 22 of of ADP hq37vm4346c 2 23 prostate prostate NOUN hq37vm4346c 2 24 cancer cancer NOUN hq37vm4346c 2 25 and and CCONJ hq37vm4346c 2 26 a a DET hq37vm4346c 2 27 vitamin vitamin NOUN hq37vm4346c 2 28 d d NOUN hq37vm4346c 2 29 receptor receptor NOUN hq37vm4346c 2 30 - - PUNCT hq37vm4346c 2 31 null null ADJ hq37vm4346c 2 32 ( ( PUNCT hq37vm4346c 2 33 vdrko vdrko PROPN hq37vm4346c 2 34 ) ) PUNCT hq37vm4346c 2 35 mouse mouse NOUN hq37vm4346c 2 36 model model NOUN hq37vm4346c 2 37 to to PART hq37vm4346c 2 38 determine determine VERB hq37vm4346c 2 39 the the DET hq37vm4346c 2 40 effects effect NOUN hq37vm4346c 2 41 of of ADP hq37vm4346c 2 42 high high ADJ hq37vm4346c 2 43 dietary dietary ADJ hq37vm4346c 2 44 calcium calcium NOUN hq37vm4346c 2 45 on on ADP hq37vm4346c 2 46 tumor tumor NOUN hq37vm4346c 2 47 progression progression NOUN hq37vm4346c 2 48 , , PUNCT hq37vm4346c 2 49 and and CCONJ hq37vm4346c 2 50 the the DET hq37vm4346c 2 51 role role NOUN hq37vm4346c 2 52 of of ADP hq37vm4346c 2 53 the the DET hq37vm4346c 2 54 vitamin vitamin NOUN hq37vm4346c 2 55 d d NOUN hq37vm4346c 2 56 receptor receptor NOUN hq37vm4346c 2 57 ( ( PUNCT hq37vm4346c 2 58 vdr vdr NOUN hq37vm4346c 2 59 ) ) PUNCT hq37vm4346c 2 60 in in ADP hq37vm4346c 2 61 prostate prostate NOUN hq37vm4346c 2 62 tumor tumor NOUN hq37vm4346c 2 63 progression progression NOUN hq37vm4346c 2 64 . . PUNCT hq37vm4346c 3 1 altered altered ADJ hq37vm4346c 3 2 levels level NOUN hq37vm4346c 3 3 of of ADP hq37vm4346c 3 4 dietary dietary ADJ hq37vm4346c 3 5 calcium calcium NOUN hq37vm4346c 3 6 did do AUX hq37vm4346c 3 7 not not PART hq37vm4346c 3 8 change change VERB hq37vm4346c 3 9 tumor tumor NOUN hq37vm4346c 3 10 progression progression NOUN hq37vm4346c 3 11 in in ADP hq37vm4346c 3 12 the the DET hq37vm4346c 3 13 lpb lpb PROPN hq37vm4346c 3 14 - - PUNCT hq37vm4346c 3 15 tag tag NOUN hq37vm4346c 3 16 mouse mouse NOUN hq37vm4346c 3 17 model model NOUN hq37vm4346c 3 18 , , PUNCT hq37vm4346c 3 19 refuting refute VERB hq37vm4346c 3 20 many many ADJ hq37vm4346c 3 21 epidemiological epidemiological ADJ hq37vm4346c 3 22 studies study NOUN hq37vm4346c 3 23 , , PUNCT hq37vm4346c 3 24 and and CCONJ hq37vm4346c 3 25 providing provide VERB hq37vm4346c 3 26 the the DET hq37vm4346c 3 27 groundwork groundwork NOUN hq37vm4346c 3 28 for for ADP hq37vm4346c 3 29 the the DET hq37vm4346c 3 30 use use NOUN hq37vm4346c 3 31 of of ADP hq37vm4346c 3 32 a a DET hq37vm4346c 3 33 high high ADJ hq37vm4346c 3 34 calcium calcium NOUN hq37vm4346c 3 35 rescue rescue NOUN hq37vm4346c 3 36 diet diet NOUN hq37vm4346c 3 37 in in ADP hq37vm4346c 3 38 later later ADJ hq37vm4346c 3 39 studies study NOUN hq37vm4346c 3 40 of of ADP hq37vm4346c 3 41 vdrko vdrko PROPN hq37vm4346c 3 42 mice mouse NOUN hq37vm4346c 3 43 . . PUNCT hq37vm4346c 4 1 in in ADP hq37vm4346c 4 2 animals animal NOUN hq37vm4346c 4 3 with with ADP hq37vm4346c 4 4 low low ADJ hq37vm4346c 4 5 levels level NOUN hq37vm4346c 4 6 of of ADP hq37vm4346c 4 7 circulating circulate VERB hq37vm4346c 4 8 testosterone testosterone NOUN hq37vm4346c 4 9 and and CCONJ hq37vm4346c 4 10 in in ADP hq37vm4346c 4 11 the the DET hq37vm4346c 4 12 absence absence NOUN hq37vm4346c 4 13 of of ADP hq37vm4346c 4 14 exogenouse exogenouse PROPN hq37vm4346c 4 15 testosterone testosterone NOUN hq37vm4346c 4 16 supplementation supplementation NOUN hq37vm4346c 4 17 , , PUNCT hq37vm4346c 4 18 the the DET hq37vm4346c 4 19 vdr vdr NOUN hq37vm4346c 4 20 confers confer VERB hq37vm4346c 4 21 protection protection NOUN hq37vm4346c 4 22 against against ADP hq37vm4346c 4 23 tumor tumor NOUN hq37vm4346c 4 24 progression progression NOUN hq37vm4346c 4 25 . . PUNCT hq37vm4346c 5 1 in in ADP hq37vm4346c 5 2 the the DET hq37vm4346c 5 3 presence presence NOUN hq37vm4346c 5 4 of of ADP hq37vm4346c 5 5 exogenous exogenous ADJ hq37vm4346c 5 6 testosterone testosterone NOUN hq37vm4346c 5 7 , , PUNCT hq37vm4346c 5 8 tumor tumor NOUN hq37vm4346c 5 9 morphology morphology NOUN hq37vm4346c 5 10 is be AUX hq37vm4346c 5 11 not not PART hq37vm4346c 5 12 different different ADJ hq37vm4346c 5 13 in in ADP hq37vm4346c 5 14 vdr vdr NOUN hq37vm4346c 5 15 wild wild ADJ hq37vm4346c 5 16 - - PUNCT hq37vm4346c 5 17 type type NOUN hq37vm4346c 5 18 ( ( PUNCT hq37vm4346c 5 19 vdrwt vdrwt NOUN hq37vm4346c 5 20 ) ) PUNCT hq37vm4346c 5 21 or or CCONJ hq37vm4346c 5 22 vdr vdr NOUN hq37vm4346c 5 23 knock knock VERB hq37vm4346c 5 24 - - PUNCT hq37vm4346c 5 25 out out ADP hq37vm4346c 5 26 ( ( PUNCT hq37vm4346c 5 27 vdrko vdrko PROPN hq37vm4346c 5 28 ) ) PUNCT hq37vm4346c 5 29 tumors tumor NOUN hq37vm4346c 5 30 , , PUNCT hq37vm4346c 5 31 suggesting suggest VERB hq37vm4346c 5 32 a a DET hq37vm4346c 5 33 loss loss NOUN hq37vm4346c 5 34 of of ADP hq37vm4346c 5 35 the the DET hq37vm4346c 5 36 protective protective ADJ hq37vm4346c 5 37 effects effect NOUN hq37vm4346c 5 38 against against ADP hq37vm4346c 5 39 tumor tumor NOUN hq37vm4346c 5 40 progression progression NOUN hq37vm4346c 5 41 . . PUNCT hq37vm4346c 6 1 vdrko vdrko PROPN hq37vm4346c 6 2 tumors tumor NOUN hq37vm4346c 6 3 show show VERB hq37vm4346c 6 4 increased increase VERB hq37vm4346c 6 5 epithelial epithelial ADJ hq37vm4346c 6 6 proliferation proliferation NOUN hq37vm4346c 6 7 , , PUNCT hq37vm4346c 6 8 resulting result VERB hq37vm4346c 6 9 in in ADP hq37vm4346c 6 10 a a DET hq37vm4346c 6 11 larger large ADJ hq37vm4346c 6 12 epithelial epithelial ADJ hq37vm4346c 6 13 compartment compartment NOUN hq37vm4346c 6 14 . . PUNCT hq37vm4346c 7 1 conversely conversely ADV hq37vm4346c 7 2 , , PUNCT hq37vm4346c 7 3 vdrwt vdrwt NOUN hq37vm4346c 7 4 tumors tumor NOUN hq37vm4346c 7 5 have have VERB hq37vm4346c 7 6 a a DET hq37vm4346c 7 7 higher high ADJ hq37vm4346c 7 8 level level NOUN hq37vm4346c 7 9 of of ADP hq37vm4346c 7 10 epithelial epithelial ADJ hq37vm4346c 7 11 apoptosis apoptosis NOUN hq37vm4346c 7 12 , , PUNCT hq37vm4346c 7 13 and and CCONJ hq37vm4346c 7 14 thus thus ADV hq37vm4346c 7 15 have have VERB hq37vm4346c 7 16 a a DET hq37vm4346c 7 17 more more ADV hq37vm4346c 7 18 pronounced pronounced ADJ hq37vm4346c 7 19 stromal stromal ADJ hq37vm4346c 7 20 compartment compartment NOUN hq37vm4346c 7 21 . . PUNCT hq37vm4346c 8 1 laser laser NOUN hq37vm4346c 8 2 capture capture VERB hq37vm4346c 8 3 microdissection microdissection NOUN hq37vm4346c 8 4 of of ADP hq37vm4346c 8 5 the the DET hq37vm4346c 8 6 epithelial epithelial ADJ hq37vm4346c 8 7 and and CCONJ hq37vm4346c 8 8 stromal stromal ADJ hq37vm4346c 8 9 layers layer NOUN hq37vm4346c 8 10 of of ADP hq37vm4346c 8 11 vdrwt vdrwt NOUN hq37vm4346c 8 12 and and CCONJ hq37vm4346c 8 13 vdrko vdrko PROPN hq37vm4346c 8 14 tumors tumor NOUN hq37vm4346c 8 15 and and CCONJ hq37vm4346c 8 16 subsequent subsequent ADJ hq37vm4346c 8 17 quantitative quantitative ADJ hq37vm4346c 8 18 rt rt NOUN hq37vm4346c 8 19 - - PUNCT hq37vm4346c 8 20 pcr pcr NOUN hq37vm4346c 8 21 shows show VERB hq37vm4346c 8 22 an an DET hq37vm4346c 8 23 overall overall ADJ hq37vm4346c 8 24 increase increase NOUN hq37vm4346c 8 25 in in ADP hq37vm4346c 8 26 genes gene NOUN hq37vm4346c 8 27 promoting promote VERB hq37vm4346c 8 28 cell cell NOUN hq37vm4346c 8 29 cycling cycling NOUN hq37vm4346c 8 30 , , PUNCT hq37vm4346c 8 31 such such ADJ hq37vm4346c 8 32 as as ADP hq37vm4346c 8 33 cyclin cyclin NOUN hq37vm4346c 8 34 - - PUNCT hq37vm4346c 8 35 dependent dependent ADJ hq37vm4346c 8 36 kinase kinase NOUN hq37vm4346c 8 37 2 2 NUM hq37vm4346c 8 38 ( ( PUNCT hq37vm4346c 8 39 cdk2 cdk2 PROPN hq37vm4346c 8 40 ) ) PUNCT hq37vm4346c 8 41 and and CCONJ hq37vm4346c 8 42 survivin survivin PROPN hq37vm4346c 8 43 in in ADP hq37vm4346c 8 44 vdrko vdrko PROPN hq37vm4346c 8 45 epithelium epithelium PROPN hq37vm4346c 8 46 and and CCONJ hq37vm4346c 8 47 stroma stroma NOUN hq37vm4346c 8 48 over over ADP hq37vm4346c 8 49 both both PRON hq37vm4346c 8 50 vdrwt vdrwt NOUN hq37vm4346c 8 51 and and CCONJ hq37vm4346c 8 52 non non ADJ hq37vm4346c 8 53 - - ADJ hq37vm4346c 8 54 transgenic transgenic ADJ hq37vm4346c 8 55 tissues tissue NOUN hq37vm4346c 8 56 . . PUNCT hq37vm4346c 9 1 epithelial epithelial ADJ hq37vm4346c 9 2 - - PUNCT hq37vm4346c 9 3 stromal stromal NOUN hq37vm4346c 9 4 signaling signaling NOUN hq37vm4346c 9 5 also also ADV hq37vm4346c 9 6 appears appear VERB hq37vm4346c 9 7 to to PART hq37vm4346c 9 8 be be AUX hq37vm4346c 9 9 enhanced enhance VERB hq37vm4346c 9 10 in in ADP hq37vm4346c 9 11 vdrko vdrko PROPN hq37vm4346c 9 12 epithelium epithelium NOUN hq37vm4346c 9 13 through through ADP hq37vm4346c 9 14 upregulation upregulation NOUN hq37vm4346c 9 15 of of ADP hq37vm4346c 9 16 the the DET hq37vm4346c 9 17 growth growth NOUN hq37vm4346c 9 18 factor factor NOUN hq37vm4346c 9 19 receptors receptor NOUN hq37vm4346c 9 20 igfr-1 igfr-1 NOUN hq37vm4346c 9 21 and and CCONJ hq37vm4346c 9 22 igfr-2 igfr-2 PROPN hq37vm4346c 9 23 . . PUNCT hq37vm4346c 9 24 loss loss NOUN hq37vm4346c 9 25 of of ADP hq37vm4346c 9 26 the the DET hq37vm4346c 9 27 vdr vdr NOUN hq37vm4346c 9 28 , , PUNCT hq37vm4346c 9 29 and and CCONJ hq37vm4346c 9 30 thus thus ADV hq37vm4346c 9 31 vitamin vitamin NOUN hq37vm4346c 9 32 d3 d3 PROPN hq37vm4346c 9 33 action action NOUN hq37vm4346c 9 34 correlates correlate VERB hq37vm4346c 9 35 with with ADP hq37vm4346c 9 36 increased increase VERB hq37vm4346c 9 37 cell cell NOUN hq37vm4346c 9 38 proliferation proliferation NOUN hq37vm4346c 9 39 , , PUNCT hq37vm4346c 9 40 decreased decrease VERB hq37vm4346c 9 41 cell cell NOUN hq37vm4346c 9 42 death death NOUN hq37vm4346c 9 43 , , PUNCT hq37vm4346c 9 44 and and CCONJ hq37vm4346c 9 45 a a DET hq37vm4346c 9 46 potential potential ADJ hq37vm4346c 9 47 increase increase NOUN hq37vm4346c 9 48 in in ADP hq37vm4346c 9 49 paracrine paracrine ADJ hq37vm4346c 9 50 growth growth NOUN hq37vm4346c 9 51 factor factor NOUN hq37vm4346c 9 52 signaling signal VERB hq37vm4346c 9 53 ; ; PUNCT hq37vm4346c 9 54 this this DET hq37vm4346c 9 55 correlation correlation NOUN hq37vm4346c 9 56 appears appear VERB hq37vm4346c 9 57 to to PART hq37vm4346c 9 58 be be AUX hq37vm4346c 9 59 affected affect VERB hq37vm4346c 9 60 by by ADP hq37vm4346c 9 61 androgen androgen NOUN hq37vm4346c 9 62 signaling signaling NOUN hq37vm4346c 9 63 , , PUNCT hq37vm4346c 9 64 and and CCONJ hq37vm4346c 9 65 has have VERB hq37vm4346c 9 66 important important ADJ hq37vm4346c 9 67 implications implication NOUN hq37vm4346c 9 68 in in ADP hq37vm4346c 9 69 co co NOUN hq37vm4346c 9 70 - - NOUN hq37vm4346c 9 71 treatment treatment NOUN hq37vm4346c 9 72 administration administration NOUN hq37vm4346c 9 73 of of ADP hq37vm4346c 9 74 anti anti ADJ hq37vm4346c 9 75 - - ADJ hq37vm4346c 9 76 androgens androgens ADJ hq37vm4346c 9 77 and and CCONJ hq37vm4346c 9 78 vitamin vitamin NOUN hq37vm4346c 9 79 d3 d3 PROPN hq37vm4346c 9 80 for for ADP hq37vm4346c 9 81 the the DET hq37vm4346c 9 82 treatment treatment NOUN hq37vm4346c 9 83 of of ADP hq37vm4346c 9 84 prostate prostate NOUN hq37vm4346c 9 85 cancer cancer NOUN hq37vm4346c 9 86 . . PUNCT