id sid tid token lemma pos kd17cr5903n 1 1 the the DET kd17cr5903n 1 2 kidneys kidney NOUN kd17cr5903n 1 3 perform perform VERB kd17cr5903n 1 4 vital vital ADJ kd17cr5903n 1 5 homeostatic homeostatic ADJ kd17cr5903n 1 6 functions function NOUN kd17cr5903n 1 7 including include VERB kd17cr5903n 1 8 osmoregulation osmoregulation NOUN kd17cr5903n 1 9 , , PUNCT kd17cr5903n 1 10 nutrient nutrient NOUN kd17cr5903n 1 11 reabsorption reabsorption NOUN kd17cr5903n 1 12 , , PUNCT kd17cr5903n 1 13 and and CCONJ kd17cr5903n 1 14 the the DET kd17cr5903n 1 15 excretion excretion NOUN kd17cr5903n 1 16 of of ADP kd17cr5903n 1 17 concentrated concentrated ADJ kd17cr5903n 1 18 nitrogenous nitrogenous ADJ kd17cr5903n 1 19 waste waste NOUN kd17cr5903n 1 20 . . PUNCT kd17cr5903n 2 1 they they PRON kd17cr5903n 2 2 are be AUX kd17cr5903n 2 3 able able ADJ kd17cr5903n 2 4 to to PART kd17cr5903n 2 5 perform perform VERB kd17cr5903n 2 6 these these DET kd17cr5903n 2 7 tasks task NOUN kd17cr5903n 2 8 through through ADP kd17cr5903n 2 9 the the DET kd17cr5903n 2 10 coordinated coordinated ADJ kd17cr5903n 2 11 activities activity NOUN kd17cr5903n 2 12 of of ADP kd17cr5903n 2 13 nephrons nephron NOUN kd17cr5903n 2 14 , , PUNCT kd17cr5903n 2 15 which which PRON kd17cr5903n 2 16 are be AUX kd17cr5903n 2 17 their their PRON kd17cr5903n 2 18 basic basic ADJ kd17cr5903n 2 19 functioning function VERB kd17cr5903n 2 20 unit unit NOUN kd17cr5903n 2 21 . . PUNCT kd17cr5903n 3 1 each each DET kd17cr5903n 3 2 nephron nephron NOUN kd17cr5903n 3 3 contains contain VERB kd17cr5903n 3 4 a a DET kd17cr5903n 3 5 proximally proximally ADV kd17cr5903n 3 6 located locate VERB kd17cr5903n 3 7 glomerulus glomerulus NOUN kd17cr5903n 3 8 that that PRON kd17cr5903n 3 9 filters filter VERB kd17cr5903n 3 10 the the DET kd17cr5903n 3 11 blood blood NOUN kd17cr5903n 3 12 as as ADV kd17cr5903n 3 13 well well ADV kd17cr5903n 3 14 as as ADP kd17cr5903n 3 15 a a DET kd17cr5903n 3 16 segmented segmented ADJ kd17cr5903n 3 17 epithelial epithelial ADJ kd17cr5903n 3 18 tubule tubule NOUN kd17cr5903n 3 19 that that PRON kd17cr5903n 3 20 drains drain VERB kd17cr5903n 3 21 into into ADP kd17cr5903n 3 22 a a DET kd17cr5903n 3 23 central central ADJ kd17cr5903n 3 24 collecting collect VERB kd17cr5903n 3 25 duct duct NOUN kd17cr5903n 3 26 system system NOUN kd17cr5903n 3 27 . . PUNCT kd17cr5903n 4 1 during during ADP kd17cr5903n 4 2 the the DET kd17cr5903n 4 3 course course NOUN kd17cr5903n 4 4 of of ADP kd17cr5903n 4 5 their their PRON kd17cr5903n 4 6 everyday everyday ADJ kd17cr5903n 4 7 function function NOUN kd17cr5903n 4 8 the the DET kd17cr5903n 4 9 nephrons nephron NOUN kd17cr5903n 4 10 encounter encounter VERB kd17cr5903n 4 11 toxins toxin NOUN kd17cr5903n 4 12 that that PRON kd17cr5903n 4 13 in in ADP kd17cr5903n 4 14 high high ADJ kd17cr5903n 4 15 concentrations concentration NOUN kd17cr5903n 4 16 can can AUX kd17cr5903n 4 17 lead lead VERB kd17cr5903n 4 18 to to ADP kd17cr5903n 4 19 an an DET kd17cr5903n 4 20 episode episode NOUN kd17cr5903n 4 21 of of ADP kd17cr5903n 4 22 acute acute ADJ kd17cr5903n 4 23 kidney kidney NOUN kd17cr5903n 4 24 injury injury NOUN kd17cr5903n 4 25 ( ( PUNCT kd17cr5903n 4 26 aki aki PROPN kd17cr5903n 4 27 ) ) PUNCT kd17cr5903n 4 28 , , PUNCT kd17cr5903n 4 29 characterized characterize VERB kd17cr5903n 4 30 by by ADP kd17cr5903n 4 31 a a DET kd17cr5903n 4 32 rapid rapid ADJ kd17cr5903n 4 33 loss loss NOUN kd17cr5903n 4 34 of of ADP kd17cr5903n 4 35 renal renal ADJ kd17cr5903n 4 36 function function NOUN kd17cr5903n 4 37 . . PUNCT kd17cr5903n 5 1 aki aki PROPN kd17cr5903n 5 2 can can AUX kd17cr5903n 5 3 progress progress VERB kd17cr5903n 5 4 to to PART kd17cr5903n 5 5 end end VERB kd17cr5903n 5 6 stage stage NOUN kd17cr5903n 5 7 renal renal ADJ kd17cr5903n 5 8 disease disease NOUN kd17cr5903n 5 9 , , PUNCT kd17cr5903n 5 10 a a DET kd17cr5903n 5 11 condition condition NOUN kd17cr5903n 5 12 in in ADP kd17cr5903n 5 13 which which PRON kd17cr5903n 5 14 the the DET kd17cr5903n 5 15 kidneys kidney NOUN kd17cr5903n 5 16 are be AUX kd17cr5903n 5 17 no no ADV kd17cr5903n 5 18 longer long ADV kd17cr5903n 5 19 functional functional ADJ kd17cr5903n 5 20 and and CCONJ kd17cr5903n 5 21 dialysis dialysis NOUN kd17cr5903n 5 22 or or CCONJ kd17cr5903n 5 23 transplantation transplantation NOUN kd17cr5903n 5 24 are be AUX kd17cr5903n 5 25 required require VERB kd17cr5903n 5 26 to to PART kd17cr5903n 5 27 sustain sustain VERB kd17cr5903n 5 28 life life NOUN kd17cr5903n 5 29 . . PUNCT kd17cr5903n 6 1 zebrafish zebrafish NOUN kd17cr5903n 6 2 , , PUNCT kd17cr5903n 6 3 unlike unlike ADP kd17cr5903n 6 4 mammals mammal NOUN kd17cr5903n 6 5 , , PUNCT kd17cr5903n 6 6 are be AUX kd17cr5903n 6 7 known know VERB kd17cr5903n 6 8 to to PART kd17cr5903n 6 9 undergo undergo VERB kd17cr5903n 6 10 robust robust ADJ kd17cr5903n 6 11 renal renal ADJ kd17cr5903n 6 12 regeneration regeneration NOUN kd17cr5903n 6 13 after after SCONJ kd17cr5903n 6 14 gentamicin gentamicin PROPN kd17cr5903n 6 15 inducted induct VERB kd17cr5903n 6 16 aki aki PROPN kd17cr5903n 6 17 . . PUNCT kd17cr5903n 7 1 to to ADP kd17cr5903n 7 2 date date NOUN kd17cr5903n 7 3 , , PUNCT kd17cr5903n 7 4 the the DET kd17cr5903n 7 5 study study NOUN kd17cr5903n 7 6 of of ADP kd17cr5903n 7 7 nephron nephron NOUN kd17cr5903n 7 8 formation formation NOUN kd17cr5903n 7 9 and and CCONJ kd17cr5903n 7 10 regeneration regeneration NOUN kd17cr5903n 7 11 in in ADP kd17cr5903n 7 12 zebrafish zebrafish NOUN kd17cr5903n 7 13 has have VERB kd17cr5903n 7 14 several several ADJ kd17cr5903n 7 15 limitations limitation NOUN kd17cr5903n 7 16 , , PUNCT kd17cr5903n 7 17 including include VERB kd17cr5903n 7 18 a a DET kd17cr5903n 7 19 relatively relatively ADV kd17cr5903n 7 20 small small ADJ kd17cr5903n 7 21 cohort cohort NOUN kd17cr5903n 7 22 of of ADP kd17cr5903n 7 23 reliable reliable ADJ kd17cr5903n 7 24 markers marker NOUN kd17cr5903n 7 25 for for ADP kd17cr5903n 7 26 distinct distinct ADJ kd17cr5903n 7 27 cell cell NOUN kd17cr5903n 7 28 types type NOUN kd17cr5903n 7 29 within within ADP kd17cr5903n 7 30 the the DET kd17cr5903n 7 31 nephron nephron NOUN kd17cr5903n 7 32 tubule tubule NOUN kd17cr5903n 7 33 . . PUNCT kd17cr5903n 8 1 in in ADP kd17cr5903n 8 2 this this DET kd17cr5903n 8 3 thesis thesis NOUN kd17cr5903n 8 4 , , PUNCT kd17cr5903n 8 5 the the DET kd17cr5903n 8 6 first first ADJ kd17cr5903n 8 7 goal goal NOUN kd17cr5903n 8 8 was be AUX kd17cr5903n 8 9 to to PART kd17cr5903n 8 10 identify identify VERB kd17cr5903n 8 11 and and CCONJ kd17cr5903n 8 12 characterize characterize VERB kd17cr5903n 8 13 a a DET kd17cr5903n 8 14 suite suite NOUN kd17cr5903n 8 15 of of ADP kd17cr5903n 8 16 useful useful ADJ kd17cr5903n 8 17 epithelial epithelial ADJ kd17cr5903n 8 18 cell cell NOUN kd17cr5903n 8 19 markers marker NOUN kd17cr5903n 8 20 . . PUNCT kd17cr5903n 9 1 my my PRON kd17cr5903n 9 2 project project NOUN kd17cr5903n 9 3 specifically specifically ADV kd17cr5903n 9 4 focused focus VERB kd17cr5903n 9 5 on on ADP kd17cr5903n 9 6 the the DET kd17cr5903n 9 7 collection collection NOUN kd17cr5903n 9 8 and and CCONJ kd17cr5903n 9 9 characterization characterization NOUN kd17cr5903n 9 10 of of ADP kd17cr5903n 9 11 tight tight ADJ kd17cr5903n 9 12 junction junction NOUN kd17cr5903n 9 13 genes gene NOUN kd17cr5903n 9 14 that that PRON kd17cr5903n 9 15 were be AUX kd17cr5903n 9 16 expressed express VERB kd17cr5903n 9 17 during during ADP kd17cr5903n 9 18 nephrogenesis nephrogenesis NOUN kd17cr5903n 9 19 . . PUNCT kd17cr5903n 10 1 a a DET kd17cr5903n 10 2 detailed detailed ADJ kd17cr5903n 10 3 spatiotemporal spatiotemporal ADJ kd17cr5903n 10 4 expression expression NOUN kd17cr5903n 10 5 study study NOUN kd17cr5903n 10 6 was be AUX kd17cr5903n 10 7 completed complete VERB kd17cr5903n 10 8 that that PRON kd17cr5903n 10 9 revealed reveal VERB kd17cr5903n 10 10 several several ADJ kd17cr5903n 10 11 aspects aspect NOUN kd17cr5903n 10 12 of of ADP kd17cr5903n 10 13 conservation conservation NOUN kd17cr5903n 10 14 between between ADP kd17cr5903n 10 15 zebrafish zebrafish NOUN kd17cr5903n 10 16 and and CCONJ kd17cr5903n 10 17 mammals mammal NOUN kd17cr5903n 10 18 , , PUNCT kd17cr5903n 10 19 including include VERB kd17cr5903n 10 20 but but CCONJ kd17cr5903n 10 21 not not PART kd17cr5903n 10 22 limited limit VERB kd17cr5903n 10 23 to to ADP kd17cr5903n 10 24 , , PUNCT kd17cr5903n 10 25 the the DET kd17cr5903n 10 26 gradient gradient NOUN kd17cr5903n 10 27 of of ADP kd17cr5903n 10 28 tight tight ADJ kd17cr5903n 10 29 junction junction NOUN kd17cr5903n 10 30 transcript transcript NOUN kd17cr5903n 10 31 expression expression NOUN kd17cr5903n 10 32 across across ADP kd17cr5903n 10 33 the the DET kd17cr5903n 10 34 proximo proximo ADJ kd17cr5903n 10 35 - - PUNCT kd17cr5903n 10 36 distal distal NOUN kd17cr5903n 10 37 length length NOUN kd17cr5903n 10 38 of of ADP kd17cr5903n 10 39 the the DET kd17cr5903n 10 40 nephron nephron NOUN kd17cr5903n 10 41 , , PUNCT kd17cr5903n 10 42 such such ADJ kd17cr5903n 10 43 that that SCONJ kd17cr5903n 10 44 distal distal ADJ kd17cr5903n 10 45 segments segment NOUN kd17cr5903n 10 46 were be AUX kd17cr5903n 10 47 found find VERB kd17cr5903n 10 48 to to PART kd17cr5903n 10 49 express express VERB kd17cr5903n 10 50 the the DET kd17cr5903n 10 51 greatest great ADJ kd17cr5903n 10 52 number number NOUN kd17cr5903n 10 53 of of ADP kd17cr5903n 10 54 factors factor NOUN kd17cr5903n 10 55 . . PUNCT kd17cr5903n 11 1 the the DET kd17cr5903n 11 2 second second ADJ kd17cr5903n 11 3 goal goal NOUN kd17cr5903n 11 4 of of ADP kd17cr5903n 11 5 this this DET kd17cr5903n 11 6 thesis thesis NOUN kd17cr5903n 11 7 was be AUX kd17cr5903n 11 8 to to PART kd17cr5903n 11 9 further far ADV kd17cr5903n 11 10 interrogate interrogate VERB kd17cr5903n 11 11 the the DET kd17cr5903n 11 12 ability ability NOUN kd17cr5903n 11 13 of of ADP kd17cr5903n 11 14 the the DET kd17cr5903n 11 15 zebrafish zebrafish NOUN kd17cr5903n 11 16 kidney kidney NOUN kd17cr5903n 11 17 to to PART kd17cr5903n 11 18 regenerate regenerate VERB kd17cr5903n 11 19 following follow VERB kd17cr5903n 11 20 injury injury NOUN kd17cr5903n 11 21 in in ADP kd17cr5903n 11 22 the the DET kd17cr5903n 11 23 embryonic embryonic NOUN kd17cr5903n 11 24 and and CCONJ kd17cr5903n 11 25 adult adult NOUN kd17cr5903n 11 26 setting setting NOUN kd17cr5903n 11 27 . . PUNCT kd17cr5903n 12 1 to to ADP kd17cr5903n 12 2 date date NOUN kd17cr5903n 12 3 , , PUNCT kd17cr5903n 12 4 the the DET kd17cr5903n 12 5 bulk bulk NOUN kd17cr5903n 12 6 of of ADP kd17cr5903n 12 7 studies study NOUN kd17cr5903n 12 8 assessing assess VERB kd17cr5903n 12 9 how how SCONJ kd17cr5903n 12 10 zebrafish zebrafish NOUN kd17cr5903n 12 11 undergo undergo VERB kd17cr5903n 12 12 renal renal ADJ kd17cr5903n 12 13 repair repair NOUN kd17cr5903n 12 14 after after ADP kd17cr5903n 12 15 injury injury NOUN kd17cr5903n 12 16 have have AUX kd17cr5903n 12 17 employed employ VERB kd17cr5903n 12 18 the the DET kd17cr5903n 12 19 antibiotic antibiotic ADJ kd17cr5903n 12 20 gentamicin gentamicin NOUN kd17cr5903n 12 21 to to PART kd17cr5903n 12 22 induce induce VERB kd17cr5903n 12 23 damage damage NOUN kd17cr5903n 12 24 and and CCONJ kd17cr5903n 12 25 therefore therefore ADV kd17cr5903n 12 26 , , PUNCT kd17cr5903n 12 27 the the DET kd17cr5903n 12 28 extent extent NOUN kd17cr5903n 12 29 to to PART kd17cr5903n 12 30 which which PRON kd17cr5903n 12 31 the the DET kd17cr5903n 12 32 kidney kidney NOUN kd17cr5903n 12 33 can can AUX kd17cr5903n 12 34 respond respond VERB kd17cr5903n 12 35 to to ADP kd17cr5903n 12 36 different different ADJ kd17cr5903n 12 37 types type NOUN kd17cr5903n 12 38 of of ADP kd17cr5903n 12 39 injury injury NOUN kd17cr5903n 12 40 remains remain VERB kd17cr5903n 12 41 unknown unknown ADJ kd17cr5903n 12 42 . . PUNCT kd17cr5903n 13 1 for for ADP kd17cr5903n 13 2 this this DET kd17cr5903n 13 3 project project NOUN kd17cr5903n 13 4 , , PUNCT kd17cr5903n 13 5 i i PRON kd17cr5903n 13 6 both both PRON kd17cr5903n 13 7 developed develop VERB kd17cr5903n 13 8 and and CCONJ kd17cr5903n 13 9 further further ADJ kd17cr5903n 13 10 refined refined ADJ kd17cr5903n 13 11 aspects aspect NOUN kd17cr5903n 13 12 of of ADP kd17cr5903n 13 13 two two NUM kd17cr5903n 13 14 parallel parallel ADJ kd17cr5903n 13 15 methodologies methodology NOUN kd17cr5903n 13 16 for for ADP kd17cr5903n 13 17 the the DET kd17cr5903n 13 18 delivery delivery NOUN kd17cr5903n 13 19 of of ADP kd17cr5903n 13 20 small small ADJ kd17cr5903n 13 21 molecules molecule NOUN kd17cr5903n 13 22 to to ADP kd17cr5903n 13 23 the the DET kd17cr5903n 13 24 zebrafish zebrafish NOUN kd17cr5903n 13 25 : : PUNCT kd17cr5903n 13 26 microinjection microinjection NOUN kd17cr5903n 13 27 in in ADP kd17cr5903n 13 28 the the DET kd17cr5903n 13 29 embryo embryo NOUN kd17cr5903n 13 30 and and CCONJ kd17cr5903n 13 31 intraperitoneal intraperitoneal ADJ kd17cr5903n 13 32 injection injection NOUN kd17cr5903n 13 33 in in ADP kd17cr5903n 13 34 the the DET kd17cr5903n 13 35 adult adult NOUN kd17cr5903n 13 36 . . PUNCT kd17cr5903n 14 1 using use VERB kd17cr5903n 14 2 the the DET kd17cr5903n 14 3 latter latter ADJ kd17cr5903n 14 4 , , PUNCT kd17cr5903n 14 5 i i PRON kd17cr5903n 14 6 established establish VERB kd17cr5903n 14 7 for for ADP kd17cr5903n 14 8 the the DET kd17cr5903n 14 9 first first ADJ kd17cr5903n 14 10 time time NOUN kd17cr5903n 14 11 that that SCONJ kd17cr5903n 14 12 the the DET kd17cr5903n 14 13 zebrafish zebrafish NOUN kd17cr5903n 14 14 kidney kidney NOUN kd17cr5903n 14 15 can can AUX kd17cr5903n 14 16 regenerate regenerate VERB kd17cr5903n 14 17 after after ADP kd17cr5903n 14 18 catastrophic catastrophic ADJ kd17cr5903n 14 19 nephron nephron NOUN kd17cr5903n 14 20 damage damage NOUN kd17cr5903n 14 21 from from ADP kd17cr5903n 14 22 the the DET kd17cr5903n 14 23 chemotherapeutic chemotherapeutic ADJ kd17cr5903n 14 24 , , PUNCT kd17cr5903n 14 25 cisplatin cisplatin NOUN kd17cr5903n 14 26 . . PUNCT kd17cr5903n 15 1 hallmarks hallmark NOUN kd17cr5903n 15 2 of of ADP kd17cr5903n 15 3 this this DET kd17cr5903n 15 4 process process NOUN kd17cr5903n 15 5 include include VERB kd17cr5903n 15 6 intratubular intratubular ADJ kd17cr5903n 15 7 repair repair NOUN kd17cr5903n 15 8 as as ADV kd17cr5903n 15 9 well well ADV kd17cr5903n 15 10 as as ADP kd17cr5903n 15 11 de de X kd17cr5903n 15 12 novo novo X kd17cr5903n 15 13 nephrogenesis nephrogenesis NOUN kd17cr5903n 15 14 , , PUNCT kd17cr5903n 15 15 which which PRON kd17cr5903n 15 16 can can AUX kd17cr5903n 15 17 be be AUX kd17cr5903n 15 18 visualized visualize VERB kd17cr5903n 15 19 with with ADP kd17cr5903n 15 20 histological histological ADJ kd17cr5903n 15 21 staining staining NOUN kd17cr5903n 15 22 . . PUNCT kd17cr5903n 16 1 i i PRON kd17cr5903n 16 2 observed observe VERB kd17cr5903n 16 3 regeneration regeneration NOUN kd17cr5903n 16 4 of of ADP kd17cr5903n 16 5 epithelial epithelial ADJ kd17cr5903n 16 6 tubules tubule NOUN kd17cr5903n 16 7 in in ADP kd17cr5903n 16 8 recovering recover VERB kd17cr5903n 16 9 fish fish NOUN kd17cr5903n 16 10 via via ADP kd17cr5903n 16 11 in in ADP kd17cr5903n 16 12 situ situ ADJ kd17cr5903n 16 13 hybridization hybridization NOUN kd17cr5903n 16 14 and and CCONJ kd17cr5903n 16 15 through through ADP kd17cr5903n 16 16 histological histological ADJ kd17cr5903n 16 17 analysis analysis NOUN kd17cr5903n 16 18 with with ADP kd17cr5903n 16 19 periodic periodic ADJ kd17cr5903n 16 20 acid acid NOUN kd17cr5903n 16 21 - - PUNCT kd17cr5903n 16 22 schiff schiff NOUN kd17cr5903n 16 23 staining staining NOUN kd17cr5903n 16 24 , , PUNCT kd17cr5903n 16 25 thereby thereby ADV kd17cr5903n 16 26 establishing establish VERB kd17cr5903n 16 27 the the DET kd17cr5903n 16 28 time time NOUN kd17cr5903n 16 29 course course NOUN kd17cr5903n 16 30 of of ADP kd17cr5903n 16 31 cellular cellular ADJ kd17cr5903n 16 32 events event NOUN kd17cr5903n 16 33 that that PRON kd17cr5903n 16 34 will will AUX kd17cr5903n 16 35 enable enable VERB kd17cr5903n 16 36 future future ADJ kd17cr5903n 16 37 studies study NOUN kd17cr5903n 16 38 to to PART kd17cr5903n 16 39 assay assay VERB kd17cr5903n 16 40 cell cell NOUN kd17cr5903n 16 41 proliferation proliferation NOUN kd17cr5903n 16 42 and and CCONJ kd17cr5903n 16 43 death death NOUN kd17cr5903n 16 44 during during ADP kd17cr5903n 16 45 the the DET kd17cr5903n 16 46 regeneration regeneration NOUN kd17cr5903n 16 47 process process NOUN