id sid tid token lemma pos n296ww74p23 1 1 despite despite SCONJ n296ww74p23 1 2 the the DET n296ww74p23 1 3 advances advance NOUN n296ww74p23 1 4 made make VERB n296ww74p23 1 5 in in ADP n296ww74p23 1 6 the the DET n296ww74p23 1 7 middle middle NOUN n296ww74p23 1 8 of of ADP n296ww74p23 1 9 the the DET n296ww74p23 1 10 20th 20th ADJ n296ww74p23 1 11 century century NOUN n296ww74p23 1 12 to to PART n296ww74p23 1 13 combat combat VERB n296ww74p23 1 14 tuberculosis tuberculosis NOUN n296ww74p23 1 15 , , PUNCT n296ww74p23 1 16 the the DET n296ww74p23 1 17 current current ADJ n296ww74p23 1 18 short short ADJ n296ww74p23 1 19 - - PUNCT n296ww74p23 1 20 course course NOUN n296ww74p23 1 21 therapy therapy NOUN n296ww74p23 1 22 has have AUX n296ww74p23 1 23 been be AUX n296ww74p23 1 24 met meet VERB n296ww74p23 1 25 with with ADP n296ww74p23 1 26 challenges challenge NOUN n296ww74p23 1 27 from from ADP n296ww74p23 1 28 multi multi ADJ n296ww74p23 1 29 - - ADJ n296ww74p23 1 30 drug drug ADJ n296ww74p23 1 31 resistant resistant ADJ n296ww74p23 1 32 strains strain NOUN n296ww74p23 1 33 of of ADP n296ww74p23 1 34 bacteria bacteria NOUN n296ww74p23 1 35 as as ADV n296ww74p23 1 36 well well ADV n296ww74p23 1 37 as as ADP n296ww74p23 1 38 the the DET n296ww74p23 1 39 inability inability NOUN n296ww74p23 1 40 of of ADP n296ww74p23 1 41 providing provide VERB n296ww74p23 1 42 these these DET n296ww74p23 1 43 drugs drug NOUN n296ww74p23 1 44 to to ADP n296ww74p23 1 45 immunocompromised immunocompromise VERB n296ww74p23 1 46 patients patient NOUN n296ww74p23 1 47 with with ADP n296ww74p23 1 48 hiv hiv PROPN n296ww74p23 1 49 . . PUNCT n296ww74p23 2 1 recent recent ADJ n296ww74p23 2 2 advances advance NOUN n296ww74p23 2 3 have have AUX n296ww74p23 2 4 been be AUX n296ww74p23 2 5 made make VERB n296ww74p23 2 6 to to PART n296ww74p23 2 7 develop develop VERB n296ww74p23 2 8 new new ADJ n296ww74p23 2 9 drugs drug NOUN n296ww74p23 2 10 that that PRON n296ww74p23 2 11 are be AUX n296ww74p23 2 12 faster fast ADV n296ww74p23 2 13 acting act VERB n296ww74p23 2 14 , , PUNCT n296ww74p23 2 15 more more ADV n296ww74p23 2 16 effective effective ADJ n296ww74p23 2 17 against against ADP n296ww74p23 2 18 drug drug NOUN n296ww74p23 2 19 - - PUNCT n296ww74p23 2 20 resistant resistant ADJ n296ww74p23 2 21 strains strain NOUN n296ww74p23 2 22 , , PUNCT n296ww74p23 2 23 and and CCONJ n296ww74p23 2 24 more more ADV n296ww74p23 2 25 compatible compatible ADJ n296ww74p23 2 26 with with ADP n296ww74p23 2 27 treatments treatment NOUN n296ww74p23 2 28 for for ADP n296ww74p23 2 29 other other ADJ n296ww74p23 2 30 diseases disease NOUN n296ww74p23 2 31 . . PUNCT n296ww74p23 3 1 sq109 sq109 VERB n296ww74p23 3 2 ( ( PUNCT n296ww74p23 3 3 1 1 X n296ww74p23 3 4 ) ) PUNCT n296ww74p23 3 5 has have AUX n296ww74p23 3 6 shown show VERB n296ww74p23 3 7 very very ADV n296ww74p23 3 8 promising promising ADJ n296ww74p23 3 9 activity activity NOUN n296ww74p23 3 10 against against ADP n296ww74p23 3 11 mycobacterium mycobacterium NOUN n296ww74p23 3 12 tuberculosis tuberculosis NOUN n296ww74p23 3 13 ( ( PUNCT n296ww74p23 3 14 mtb mtb NOUN n296ww74p23 3 15 ) ) PUNCT n296ww74p23 3 16 , , PUNCT n296ww74p23 3 17 but but CCONJ n296ww74p23 3 18 exhibits exhibit VERB n296ww74p23 3 19 low low ADJ n296ww74p23 3 20 oral oral ADJ n296ww74p23 3 21 bioavailability bioavailability NOUN n296ww74p23 3 22 . . PUNCT n296ww74p23 4 1 this this DET n296ww74p23 4 2 project project NOUN n296ww74p23 4 3 was be AUX n296ww74p23 4 4 begun begin VERB n296ww74p23 4 5 to to PART n296ww74p23 4 6 develop develop VERB n296ww74p23 4 7 stronger strong ADJ n296ww74p23 4 8 and and CCONJ n296ww74p23 4 9 more more ADV n296ww74p23 4 10 potent potent ADJ n296ww74p23 4 11 analogs analog NOUN n296ww74p23 4 12 of of ADP n296ww74p23 4 13 sq109 sq109 VERB n296ww74p23 4 14 by by ADP n296ww74p23 4 15 using use VERB n296ww74p23 4 16 nitroso nitroso NOUN n296ww74p23 4 17 ene ene ADJ n296ww74p23 4 18 chemistry chemistry NOUN n296ww74p23 4 19 and and CCONJ n296ww74p23 4 20 testing test VERB n296ww74p23 4 21 them they PRON n296ww74p23 4 22 against against ADP n296ww74p23 4 23 various various ADJ n296ww74p23 4 24 strains strain NOUN n296ww74p23 4 25 of of ADP n296ww74p23 4 26 bacteria bacteria NOUN n296ww74p23 4 27 , , PUNCT n296ww74p23 4 28 including include VERB n296ww74p23 4 29 mtb mtb NOUN n296ww74p23 4 30 . . PUNCT n296ww74p23 5 1 the the DET n296ww74p23 5 2 synthesis synthesis NOUN n296ww74p23 5 3 of of ADP n296ww74p23 5 4 sq109 sq109 PROPN n296ww74p23 5 5 was be AUX n296ww74p23 5 6 improved improve VERB n296ww74p23 5 7 from from ADP n296ww74p23 5 8 original original ADJ n296ww74p23 5 9 reports report NOUN n296ww74p23 5 10 to to PART n296ww74p23 5 11 allow allow VERB n296ww74p23 5 12 for for ADP n296ww74p23 5 13 a a DET n296ww74p23 5 14 more more ADV n296ww74p23 5 15 scalable scalable ADJ n296ww74p23 5 16 synthesis synthesis NOUN n296ww74p23 5 17 . . PUNCT n296ww74p23 6 1 also also ADV n296ww74p23 6 2 , , PUNCT n296ww74p23 6 3 two two NUM n296ww74p23 6 4 precursor precursor NOUN n296ww74p23 6 5 analogs analog NOUN n296ww74p23 6 6 of of ADP n296ww74p23 6 7 the the DET n296ww74p23 6 8 compound compound NOUN n296ww74p23 6 9 in in ADP n296ww74p23 6 10 the the DET n296ww74p23 6 11 attempted attempt VERB n296ww74p23 6 12 syntheses synthesis NOUN n296ww74p23 6 13 were be AUX n296ww74p23 6 14 found find VERB n296ww74p23 6 15 to to PART n296ww74p23 6 16 be be AUX n296ww74p23 6 17 surprisingly surprisingly ADV n296ww74p23 6 18 biologically biologically ADV n296ww74p23 6 19 active active ADJ n296ww74p23 6 20 . . PUNCT n296ww74p23 7 1 nitroso nitroso PROPN n296ww74p23 7 2 - - PUNCT n296ww74p23 7 3 ene ene PROPN n296ww74p23 7 4 chemistry chemistry NOUN n296ww74p23 7 5 was be AUX n296ww74p23 7 6 performed perform VERB n296ww74p23 7 7 on on ADP n296ww74p23 7 8 these these PRON n296ww74p23 7 9 as as ADV n296ww74p23 7 10 well well ADV n296ww74p23 7 11 as as ADP n296ww74p23 7 12 some some DET n296ww74p23 7 13 other other ADJ n296ww74p23 7 14 simple simple ADJ n296ww74p23 7 15 isoprenoids isoprenoid NOUN n296ww74p23 7 16 in in ADP n296ww74p23 7 17 order order NOUN n296ww74p23 7 18 to to PART n296ww74p23 7 19 discover discover VERB n296ww74p23 7 20 even even ADV n296ww74p23 7 21 more more ADJ n296ww74p23 7 22 compounds compound NOUN n296ww74p23 7 23 with with ADP n296ww74p23 7 24 antibacterial antibacterial ADJ n296ww74p23 7 25 activity activity NOUN n296ww74p23 7 26 . . PUNCT