id sid tid token lemma pos r781wd4098p 1 1 nowadays nowadays ADV r781wd4098p 1 2 , , PUNCT r781wd4098p 1 3 over over ADP r781wd4098p 1 4 80 80 NUM r781wd4098p 1 5 % % NOUN r781wd4098p 1 6 of of ADP r781wd4098p 1 7 energy energy NOUN r781wd4098p 1 8 supply supply NOUN r781wd4098p 1 9 relies rely VERB r781wd4098p 1 10 on on ADP r781wd4098p 1 11 the the DET r781wd4098p 1 12 nonrenewable nonrenewable ADJ r781wd4098p 1 13 and and CCONJ r781wd4098p 1 14 environmental environmental ADJ r781wd4098p 1 15 unfriendly unfriendly ADJ r781wd4098p 1 16 fossil fossil ADJ r781wd4098p 1 17 fuels fuel NOUN r781wd4098p 1 18 . . PUNCT r781wd4098p 2 1 meanwhile meanwhile ADV r781wd4098p 2 2 , , PUNCT r781wd4098p 2 3 occurrence occurrence NOUN r781wd4098p 2 4 of of ADP r781wd4098p 2 5 pharmaceuticals pharmaceutical NOUN r781wd4098p 2 6 and and CCONJ r781wd4098p 2 7 chemicals chemical NOUN r781wd4098p 2 8 originated originate VERB r781wd4098p 2 9 from from ADP r781wd4098p 2 10 our our PRON r781wd4098p 2 11 daily daily ADJ r781wd4098p 2 12 life life NOUN r781wd4098p 2 13 and and CCONJ r781wd4098p 2 14 industrial industrial ADJ r781wd4098p 2 15 activities activity NOUN r781wd4098p 2 16 but but CCONJ r781wd4098p 2 17 associated associate VERB r781wd4098p 2 18 with with ADP r781wd4098p 2 19 potential potential ADJ r781wd4098p 2 20 environmental environmental ADJ r781wd4098p 2 21 risks risk NOUN r781wd4098p 2 22 in in ADP r781wd4098p 2 23 the the DET r781wd4098p 2 24 aquatic aquatic ADJ r781wd4098p 2 25 environment environment NOUN r781wd4098p 2 26 evokes evoke VERB r781wd4098p 2 27 increasing increase VERB r781wd4098p 2 28 public public ADJ r781wd4098p 2 29 concern concern NOUN r781wd4098p 2 30 about about ADP r781wd4098p 2 31 reclaimed reclaimed ADJ r781wd4098p 2 32 water water NOUN r781wd4098p 2 33 . . PUNCT r781wd4098p 3 1 this this DET r781wd4098p 3 2 research research NOUN r781wd4098p 3 3 stays stay VERB r781wd4098p 3 4 at at ADP r781wd4098p 3 5 the the DET r781wd4098p 3 6 interface interface NOUN r781wd4098p 3 7 of of ADP r781wd4098p 3 8 environmental environmental ADJ r781wd4098p 3 9 engineering engineering NOUN r781wd4098p 3 10 and and CCONJ r781wd4098p 3 11 metabolic metabolic NOUN r781wd4098p 3 12 engineering engineering NOUN r781wd4098p 3 13 , , PUNCT r781wd4098p 3 14 with with ADP r781wd4098p 3 15 the the DET r781wd4098p 3 16 goal goal NOUN r781wd4098p 3 17 of of ADP r781wd4098p 3 18 manipulating manipulate VERB r781wd4098p 3 19 and and CCONJ r781wd4098p 3 20 engineering engineer VERB r781wd4098p 3 21 yeast yeast NOUN r781wd4098p 3 22 to to PART r781wd4098p 3 23 enhance enhance VERB r781wd4098p 3 24 renewable renewable ADJ r781wd4098p 3 25 energy energy NOUN r781wd4098p 3 26 biofuel biofuel NOUN r781wd4098p 3 27 production production NOUN r781wd4098p 3 28 from from ADP r781wd4098p 3 29 lignocellulosic lignocellulosic NOUN r781wd4098p 3 30 residues residue NOUN r781wd4098p 3 31 and and CCONJ r781wd4098p 3 32 to to PART r781wd4098p 3 33 treat treat VERB r781wd4098p 3 34 contaminants contaminant NOUN r781wd4098p 3 35 of of ADP r781wd4098p 3 36 emerging emerge VERB r781wd4098p 3 37 concerns concern NOUN r781wd4098p 3 38 for for ADP r781wd4098p 3 39 water water NOUN r781wd4098p 3 40 reuse reuse PROPN r781wd4098p 3 41 / / SYM r781wd4098p 3 42 reclamation.the reclamation.the DET r781wd4098p 3 43 development development NOUN r781wd4098p 3 44 of of ADP r781wd4098p 3 45 robust robust ADJ r781wd4098p 3 46 microbial microbial ADJ r781wd4098p 3 47 systems system NOUN r781wd4098p 3 48 to to PART r781wd4098p 3 49 utilize utilize VERB r781wd4098p 3 50 renewable renewable ADJ r781wd4098p 3 51 feedstock feedstock NOUN r781wd4098p 3 52 effectively effectively ADV r781wd4098p 3 53 is be AUX r781wd4098p 3 54 important important ADJ r781wd4098p 3 55 for for ADP r781wd4098p 3 56 high high ADJ r781wd4098p 3 57 - - PUNCT r781wd4098p 3 58 titer titer NOUN r781wd4098p 3 59 biofuels biofuel NOUN r781wd4098p 3 60 production production NOUN r781wd4098p 3 61 . . PUNCT r781wd4098p 4 1 lignocellulosic lignocellulosic PROPN r781wd4098p 4 2 biomass biomass PROPN r781wd4098p 4 3 has have AUX r781wd4098p 4 4 been be AUX r781wd4098p 4 5 identified identify VERB r781wd4098p 4 6 as as ADP r781wd4098p 4 7 a a DET r781wd4098p 4 8 promising promising ADJ r781wd4098p 4 9 source source NOUN r781wd4098p 4 10 to to PART r781wd4098p 4 11 produce produce VERB r781wd4098p 4 12 renewable renewable ADJ r781wd4098p 4 13 biofuels biofuel NOUN r781wd4098p 4 14 but but CCONJ r781wd4098p 4 15 the the DET r781wd4098p 4 16 pretreatment pretreatment NOUN r781wd4098p 4 17 of of ADP r781wd4098p 4 18 lignocellulosic lignocellulosic PROPN r781wd4098p 4 19 biomass biomass PROPN r781wd4098p 4 20 generates generate VERB r781wd4098p 4 21 lignocellulosic lignocellulosic PROPN r781wd4098p 4 22 hydrolysate hydrolysate NOUN r781wd4098p 4 23 that that PRON r781wd4098p 4 24 contains contain VERB r781wd4098p 4 25 fermentation fermentation NOUN r781wd4098p 4 26 inhibitors inhibitor NOUN r781wd4098p 4 27 . . PUNCT r781wd4098p 5 1 the the DET r781wd4098p 5 2 fermentation fermentation NOUN r781wd4098p 5 3 inhibitors inhibitor NOUN r781wd4098p 5 4 will will AUX r781wd4098p 5 5 adversely adversely ADV r781wd4098p 5 6 affect affect VERB r781wd4098p 5 7 the the DET r781wd4098p 5 8 growth growth NOUN r781wd4098p 5 9 of of ADP r781wd4098p 5 10 industrial industrial ADJ r781wd4098p 5 11 microorganisms microorganism NOUN r781wd4098p 5 12 such such ADJ r781wd4098p 5 13 as as ADP r781wd4098p 5 14 saccharomyces saccharomyce NOUN r781wd4098p 5 15 cerevisiae cerevisiae NOUN r781wd4098p 5 16 and and CCONJ r781wd4098p 5 17 prevent prevent VERB r781wd4098p 5 18 economic economic ADJ r781wd4098p 5 19 production production NOUN r781wd4098p 5 20 of of ADP r781wd4098p 5 21 lignocellulosic lignocellulosic PROPN r781wd4098p 5 22 biofuels biofuel NOUN r781wd4098p 5 23 . . PUNCT r781wd4098p 6 1 therefore therefore ADV r781wd4098p 6 2 , , PUNCT r781wd4098p 6 3 it it PRON r781wd4098p 6 4 is be AUX r781wd4098p 6 5 critical critical ADJ r781wd4098p 6 6 to to PART r781wd4098p 6 7 engineer engineer VERB r781wd4098p 6 8 microbial microbial ADJ r781wd4098p 6 9 cell cell NOUN r781wd4098p 6 10 systems system NOUN r781wd4098p 6 11 with with ADP r781wd4098p 6 12 enhanced enhanced ADJ r781wd4098p 6 13 resistance resistance NOUN r781wd4098p 6 14 to to ADP r781wd4098p 6 15 fermentation fermentation NOUN r781wd4098p 6 16 inhibitors inhibitor NOUN r781wd4098p 6 17 . . PUNCT r781wd4098p 7 1 this this DET r781wd4098p 7 2 study study NOUN r781wd4098p 7 3 employed employ VERB r781wd4098p 7 4 a a DET r781wd4098p 7 5 genomic genomic NOUN r781wd4098p 7 6 library library NOUN r781wd4098p 7 7 based base VERB r781wd4098p 7 8 inverse inverse ADJ r781wd4098p 7 9 metabolic metabolic NOUN r781wd4098p 7 10 engineering engineering NOUN r781wd4098p 7 11 approach approach NOUN r781wd4098p 7 12 to to PART r781wd4098p 7 13 successfully successfully ADV r781wd4098p 7 14 identify identify VERB r781wd4098p 7 15 a a DET r781wd4098p 7 16 novel novel ADJ r781wd4098p 7 17 gene gene NOUN r781wd4098p 7 18 target target NOUN r781wd4098p 7 19 whi2 whi2 PROPN r781wd4098p 7 20 which which PRON r781wd4098p 7 21 elicited elicit VERB r781wd4098p 7 22 improved improve VERB r781wd4098p 7 23 acetic acetic ADJ r781wd4098p 7 24 acid acid NOUN r781wd4098p 7 25 resistance resistance NOUN r781wd4098p 7 26 in in ADP r781wd4098p 7 27 s. s. PROPN r781wd4098p 7 28 cerevisiae cerevisiae NOUN r781wd4098p 7 29 . . PUNCT r781wd4098p 8 1 based base VERB r781wd4098p 8 2 on on ADP r781wd4098p 8 3 this this DET r781wd4098p 8 4 study study NOUN r781wd4098p 8 5 , , PUNCT r781wd4098p 8 6 we we PRON r781wd4098p 8 7 developed develop VERB r781wd4098p 8 8 an an DET r781wd4098p 8 9 engineered engineer VERB r781wd4098p 8 10 yeast yeast NOUN r781wd4098p 8 11 strain strain NOUN r781wd4098p 8 12 yc1 yc1 NUM r781wd4098p 8 13 with with ADP r781wd4098p 8 14 superior superior ADJ r781wd4098p 8 15 resistance resistance NOUN r781wd4098p 8 16 to to ADP r781wd4098p 8 17 acetic acetic ADJ r781wd4098p 8 18 acid acid NOUN r781wd4098p 8 19 , , PUNCT r781wd4098p 8 20 furfural furfural ADJ r781wd4098p 8 21 and and CCONJ r781wd4098p 8 22 their their PRON r781wd4098p 8 23 mixture mixture NOUN r781wd4098p 8 24 . . PUNCT r781wd4098p 9 1 the the DET r781wd4098p 9 2 transcriptional transcriptional ADJ r781wd4098p 9 3 changes change NOUN r781wd4098p 9 4 in in ADP r781wd4098p 9 5 yc1 yc1 NUM r781wd4098p 9 6 versus versus ADP r781wd4098p 9 7 the the DET r781wd4098p 9 8 wild wild ADJ r781wd4098p 9 9 - - PUNCT r781wd4098p 9 10 type type NOUN r781wd4098p 9 11 strain strain NOUN r781wd4098p 9 12 s s NOUN r781wd4098p 9 13 - - NOUN r781wd4098p 9 14 c1 c1 NOUN r781wd4098p 9 15 under under ADP r781wd4098p 9 16 three three NUM r781wd4098p 9 17 different different ADJ r781wd4098p 9 18 inhibitor inhibitor NOUN r781wd4098p 9 19 conditions condition NOUN r781wd4098p 9 20 , , PUNCT r781wd4098p 9 21 including include VERB r781wd4098p 9 22 acetic acetic ADJ r781wd4098p 9 23 acid acid NOUN r781wd4098p 9 24 alone alone ADV r781wd4098p 9 25 , , PUNCT r781wd4098p 9 26 furfural furfural ADJ r781wd4098p 9 27 alone alone ADV r781wd4098p 9 28 and and CCONJ r781wd4098p 9 29 mixture mixture NOUN r781wd4098p 9 30 of of ADP r781wd4098p 9 31 acetic acetic ADJ r781wd4098p 9 32 acid acid NOUN r781wd4098p 9 33 and and CCONJ r781wd4098p 9 34 furfural furfural ADJ r781wd4098p 9 35 were be AUX r781wd4098p 9 36 determined determine VERB r781wd4098p 9 37 through through ADP r781wd4098p 9 38 rna rna NOUN r781wd4098p 9 39 sequencing sequencing NOUN r781wd4098p 9 40 . . PUNCT r781wd4098p 10 1 the the DET r781wd4098p 10 2 establishment establishment NOUN r781wd4098p 10 3 of of ADP r781wd4098p 10 4 green green ADJ r781wd4098p 10 5 and and CCONJ r781wd4098p 10 6 cost cost NOUN r781wd4098p 10 7 - - PUNCT r781wd4098p 10 8 effective effective ADJ r781wd4098p 10 9 biotechnology biotechnology NOUN r781wd4098p 10 10 to to PART r781wd4098p 10 11 treat treat VERB r781wd4098p 10 12 emerging emerge VERB r781wd4098p 10 13 contaminants contaminant NOUN r781wd4098p 10 14 is be AUX r781wd4098p 10 15 also also ADV r781wd4098p 10 16 important important ADJ r781wd4098p 10 17 for for ADP r781wd4098p 10 18 advancing advance VERB r781wd4098p 10 19 water water NOUN r781wd4098p 10 20 reuse reuse NOUN r781wd4098p 10 21 / / SYM r781wd4098p 10 22 reclamation reclamation NOUN r781wd4098p 10 23 . . PUNCT r781wd4098p 11 1 we we PRON r781wd4098p 11 2 developed develop VERB r781wd4098p 11 3 a a DET r781wd4098p 11 4 new new ADJ r781wd4098p 11 5 type type NOUN r781wd4098p 11 6 of of ADP r781wd4098p 11 7 biocatalyst biocatalyst NOUN r781wd4098p 11 8 by by ADP r781wd4098p 11 9 immobilizing immobilize VERB r781wd4098p 11 10 fungal fungal ADJ r781wd4098p 11 11 laccase laccase NOUN r781wd4098p 11 12 on on ADP r781wd4098p 11 13 the the DET r781wd4098p 11 14 surface surface NOUN r781wd4098p 11 15 of of ADP r781wd4098p 11 16 yeast yeast NOUN r781wd4098p 11 17 cells cell NOUN r781wd4098p 11 18 using use VERB r781wd4098p 11 19 synthetic synthetic ADJ r781wd4098p 11 20 biology biology NOUN r781wd4098p 11 21 techniques technique NOUN r781wd4098p 11 22 . . PUNCT r781wd4098p 12 1 followed follow VERB r781wd4098p 12 2 by by ADP r781wd4098p 12 3 sdl sdl PROPN r781wd4098p 12 4 study study NOUN r781wd4098p 12 5 , , PUNCT r781wd4098p 12 6 we we PRON r781wd4098p 12 7 fabricated fabricate VERB r781wd4098p 12 8 biocatalytic biocatalytic ADJ r781wd4098p 12 9 membranes membrane NOUN r781wd4098p 12 10 ( ( PUNCT r781wd4098p 12 11 bcms bcms NOUN r781wd4098p 12 12 ) ) PUNCT r781wd4098p 12 13 by by ADP r781wd4098p 12 14 immobilizing immobilize VERB r781wd4098p 12 15 sdl sdl NOUN r781wd4098p 12 16 on on ADP r781wd4098p 12 17 microporous microporous ADJ r781wd4098p 12 18 membranes membrane NOUN r781wd4098p 12 19 via via ADP r781wd4098p 12 20 inkjet inkjet NOUN r781wd4098p 12 21 printing printing NOUN r781wd4098p 12 22 and and CCONJ r781wd4098p 12 23 chemical chemical NOUN r781wd4098p 12 24 crosslinking crosslinking NOUN r781wd4098p 12 25 . . PUNCT r781wd4098p 13 1 both both PRON r781wd4098p 13 2 sdl sdl VERB r781wd4098p 13 3 and and CCONJ r781wd4098p 13 4 bcms bcms PROPN r781wd4098p 13 5 could could AUX r781wd4098p 13 6 effectively effectively ADV r781wd4098p 13 7 treat treat VERB r781wd4098p 13 8 emerging emerge VERB r781wd4098p 13 9 contaminants contaminant NOUN r781wd4098p 13 10 . . PUNCT r781wd4098p 14 1 the the DET r781wd4098p 14 2 research research NOUN r781wd4098p 14 3 offers offer VERB r781wd4098p 14 4 a a DET r781wd4098p 14 5 practice practice NOUN r781wd4098p 14 6 to to PART r781wd4098p 14 7 develop develop VERB r781wd4098p 14 8 robust robust ADJ r781wd4098p 14 9 strains strain NOUN r781wd4098p 14 10 for for ADP r781wd4098p 14 11 enhanced enhanced ADJ r781wd4098p 14 12 lignocellulosic lignocellulosic NOUN r781wd4098p 14 13 biofuel biofuel NOUN r781wd4098p 14 14 production production NOUN r781wd4098p 14 15 and and CCONJ r781wd4098p 14 16 a a DET r781wd4098p 14 17 novel novel ADJ r781wd4098p 14 18 category category NOUN r781wd4098p 14 19 of of ADP r781wd4098p 14 20 enzyme enzyme NOUN r781wd4098p 14 21 biocatalysts biocatalyst NOUN r781wd4098p 14 22 for for ADP r781wd4098p 14 23 treating treat VERB r781wd4098p 14 24 emerging emerge VERB r781wd4098p 14 25 contaminants contaminant NOUN r781wd4098p 14 26 for for ADP r781wd4098p 14 27 water water NOUN r781wd4098p 14 28 reuse reuse NOUN r781wd4098p 14 29 . . PUNCT r781wd4098p 15 1 our our PRON r781wd4098p 15 2 data datum NOUN r781wd4098p 15 3 demonstrated demonstrate VERB r781wd4098p 15 4 the the DET r781wd4098p 15 5 effectiveness effectiveness NOUN r781wd4098p 15 6 of of ADP r781wd4098p 15 7 engineered engineer VERB r781wd4098p 15 8 cell cell NOUN r781wd4098p 15 9 systems system NOUN r781wd4098p 15 10 in in ADP r781wd4098p 15 11 advancing advance VERB r781wd4098p 15 12 renewable renewable ADJ r781wd4098p 15 13 energy energy NOUN r781wd4098p 15 14 production production NOUN r781wd4098p 15 15 and and CCONJ r781wd4098p 15 16 water water NOUN r781wd4098p 15 17 treatment treatment NOUN r781wd4098p 15 18 . . PUNCT r781wd4098p 16 1 these these PRON r781wd4098p 16 2 and and CCONJ r781wd4098p 16 3 similar similar ADJ r781wd4098p 16 4 cell cell NOUN r781wd4098p 16 5 systems system NOUN r781wd4098p 16 6 could could AUX r781wd4098p 16 7 have have VERB r781wd4098p 16 8 a a DET r781wd4098p 16 9 critical critical ADJ r781wd4098p 16 10 role role NOUN r781wd4098p 16 11 in in ADP r781wd4098p 16 12 addressing address VERB r781wd4098p 16 13 other other ADJ r781wd4098p 16 14 challenges challenge NOUN r781wd4098p 16 15 towards towards ADP r781wd4098p 16 16 environmental environmental ADJ r781wd4098p 16 17 sustainability sustainability NOUN r781wd4098p 16 18 . . PUNCT