id	sid	tid	token	lemma	pos
sq87br88t3x	1	1	tissue	tissue	NOUN
sq87br88t3x	1	2	development	development	NOUN
sq87br88t3x	1	3	and	and	CCONJ
sq87br88t3x	1	4	maintenance	maintenance	NOUN
sq87br88t3x	1	5	rely	rely	VERB
sq87br88t3x	1	6	upon	upon	SCONJ
sq87br88t3x	1	7	choreographed	choreographed	ADJ
sq87br88t3x	1	8	cell	cell	NOUN
sq87br88t3x	1	9	signaling	signaling	NOUN
sq87br88t3x	1	10	,	,	PUNCT
sq87br88t3x	1	11	dynamic	dynamic	ADJ
sq87br88t3x	1	12	cell	cell	NOUN
sq87br88t3x	1	13	-	-	PUNCT
sq87br88t3x	1	14	cell	cell	NOUN
sq87br88t3x	1	15	and	and	CCONJ
sq87br88t3x	1	16	cell	cell	NOUN
sq87br88t3x	1	17	-	-	PUNCT
sq87br88t3x	1	18	matrix	matrix	NOUN
sq87br88t3x	1	19	interactions	interaction	NOUN
sq87br88t3x	1	20	,	,	PUNCT
sq87br88t3x	1	21	and	and	CCONJ
sq87br88t3x	1	22	a	a	DET
sq87br88t3x	1	23	precise	precise	ADJ
sq87br88t3x	1	24	interplay	interplay	NOUN
sq87br88t3x	1	25	between	between	ADP
sq87br88t3x	1	26	the	the	DET
sq87br88t3x	1	27	matrix	matrix	NOUN
sq87br88t3x	1	28	and	and	CCONJ
sq87br88t3x	1	29	the	the	DET
sq87br88t3x	1	30	cells	cell	NOUN
sq87br88t3x	1	31	to	to	PART
sq87br88t3x	1	32	promote	promote	VERB
sq87br88t3x	1	33	intercellular	intercellular	ADJ
sq87br88t3x	1	34	organization	organization	NOUN
sq87br88t3x	1	35	,	,	PUNCT
sq87br88t3x	1	36	differentiation	differentiation	NOUN
sq87br88t3x	1	37	,	,	PUNCT
sq87br88t3x	1	38	and	and	CCONJ
sq87br88t3x	1	39	cell	cell	NOUN
sq87br88t3x	1	40	survival	survival	NOUN
sq87br88t3x	1	41	.	.	PUNCT
sq87br88t3x	2	1	epithelial	epithelial	ADJ
sq87br88t3x	2	2	cancer	cancer	NOUN
sq87br88t3x	2	3	progression	progression	NOUN
sq87br88t3x	2	4	is	be	AUX
sq87br88t3x	2	5	generally	generally	ADV
sq87br88t3x	2	6	the	the	DET
sq87br88t3x	2	7	result	result	NOUN
sq87br88t3x	2	8	of	of	ADP
sq87br88t3x	2	9	the	the	DET
sq87br88t3x	2	10	deregulation	deregulation	NOUN
sq87br88t3x	2	11	of	of	ADP
sq87br88t3x	2	12	these	these	DET
sq87br88t3x	2	13	processes	process	NOUN
sq87br88t3x	2	14	,	,	PUNCT
sq87br88t3x	2	15	and	and	CCONJ
sq87br88t3x	2	16	is	be	AUX
sq87br88t3x	2	17	accompanied	accompany	VERB
sq87br88t3x	2	18	by	by	ADP
sq87br88t3x	2	19	the	the	DET
sq87br88t3x	2	20	disruption	disruption	NOUN
sq87br88t3x	2	21	of	of	ADP
sq87br88t3x	2	22	epithelial	epithelial	ADJ
sq87br88t3x	2	23	architecture	architecture	NOUN
sq87br88t3x	2	24	.	.	PUNCT
sq87br88t3x	3	1	the	the	DET
sq87br88t3x	3	2	emergence	emergence	NOUN
sq87br88t3x	3	3	of	of	ADP
sq87br88t3x	3	4	three	three	NUM
sq87br88t3x	3	5	-	-	PUNCT
sq87br88t3x	3	6	dimensional	dimensional	ADJ
sq87br88t3x	3	7	(	(	PUNCT
sq87br88t3x	3	8	3d	3d	NOUN
sq87br88t3x	3	9	)	)	PUNCT
sq87br88t3x	3	10	cell	cell	NOUN
sq87br88t3x	3	11	models	model	NOUN
sq87br88t3x	3	12	has	have	AUX
sq87br88t3x	3	13	led	lead	VERB
sq87br88t3x	3	14	to	to	ADP
sq87br88t3x	3	15	a	a	DET
sq87br88t3x	3	16	deeper	deep	ADJ
sq87br88t3x	3	17	understanding	understanding	NOUN
sq87br88t3x	3	18	of	of	ADP
sq87br88t3x	3	19	tissue	tissue	NOUN
sq87br88t3x	3	20	-	-	PUNCT
sq87br88t3x	3	21	specific	specific	ADJ
sq87br88t3x	3	22	behaviors	behavior	NOUN
sq87br88t3x	3	23	by	by	ADP
sq87br88t3x	3	24	modeling	model	VERB
sq87br88t3x	3	25	both	both	DET
sq87br88t3x	3	26	physiological	physiological	ADJ
sq87br88t3x	3	27	events	event	NOUN
sq87br88t3x	3	28	as	as	ADV
sq87br88t3x	3	29	well	well	ADV
sq87br88t3x	3	30	as	as	ADP
sq87br88t3x	3	31	the	the	DET
sq87br88t3x	3	32	progression	progression	NOUN
sq87br88t3x	3	33	of	of	ADP
sq87br88t3x	3	34	disease	disease	NOUN
sq87br88t3x	3	35	states	state	NOUN
sq87br88t3x	3	36	.	.	PUNCT
sq87br88t3x	4	1	here	here	ADV
sq87br88t3x	4	2	,	,	PUNCT
sq87br88t3x	4	3	we	we	PRON
sq87br88t3x	4	4	contribute	contribute	VERB
sq87br88t3x	4	5	to	to	ADP
sq87br88t3x	4	6	the	the	DET
sq87br88t3x	4	7	understanding	understanding	NOUN
sq87br88t3x	4	8	of	of	ADP
sq87br88t3x	4	9	the	the	DET
sq87br88t3x	4	10	role	role	NOUN
sq87br88t3x	4	11	of	of	ADP
sq87br88t3x	4	12	arf6	arf6	NOUN
sq87br88t3x	4	13	in	in	ADP
sq87br88t3x	4	14	epithelial	epithelial	ADJ
sq87br88t3x	4	15	tissue	tissue	NOUN
sq87br88t3x	4	16	morphogenesis	morphogenesis	NOUN
sq87br88t3x	4	17	by	by	ADP
sq87br88t3x	4	18	utilizing	utilize	VERB
sq87br88t3x	4	19	3d	3d	PRON
sq87br88t3x	4	20	basement	basement	NOUN
sq87br88t3x	4	21	membrane	membrane	NOUN
sq87br88t3x	4	22	cultures	culture	NOUN
sq87br88t3x	4	23	that	that	PRON
sq87br88t3x	4	24	model	model	VERB
sq87br88t3x	4	25	glandular	glandular	ADJ
sq87br88t3x	4	26	architecture	architecture	NOUN
sq87br88t3x	4	27	and	and	CCONJ
sq87br88t3x	4	28	its	its	PRON
sq87br88t3x	4	29	microenvironment	microenvironment	NOUN
sq87br88t3x	4	30	.	.	PUNCT
sq87br88t3x	5	1	we	we	PRON
sq87br88t3x	5	2	demonstrate	demonstrate	VERB
sq87br88t3x	5	3	that	that	SCONJ
sq87br88t3x	5	4	renal	renal	ADJ
sq87br88t3x	5	5	epithelial	epithelial	ADJ
sq87br88t3x	5	6	cysts	cyst	NOUN
sq87br88t3x	5	7	require	require	VERB
sq87br88t3x	5	8	arf6	arf6	PROPN
sq87br88t3x	5	9	to	to	ADP
sq87br88t3x	5	10	orient	orient	ADJ
sq87br88t3x	5	11	cellular	cellular	ADJ
sq87br88t3x	5	12	polarity	polarity	NOUN
sq87br88t3x	5	13	and	and	CCONJ
sq87br88t3x	5	14	to	to	PART
sq87br88t3x	5	15	deliver	deliver	VERB
sq87br88t3x	5	16	and	and	CCONJ
sq87br88t3x	5	17	assemble	assemble	VERB
sq87br88t3x	5	18	laminin	laminin	NOUN
sq87br88t3x	5	19	into	into	ADP
sq87br88t3x	5	20	a	a	DET
sq87br88t3x	5	21	supportive	supportive	ADJ
sq87br88t3x	5	22	basement	basement	NOUN
sq87br88t3x	5	23	membrane	membrane	NOUN
sq87br88t3x	5	24	network	network	NOUN
sq87br88t3x	5	25	.	.	PUNCT
sq87br88t3x	6	1	cellular	cellular	ADJ
sq87br88t3x	6	2	depletion	depletion	NOUN
sq87br88t3x	6	3	of	of	ADP
sq87br88t3x	6	4	arf6	arf6	PROPN
sq87br88t3x	6	5	expression	expression	NOUN
sq87br88t3x	6	6	results	result	VERB
sq87br88t3x	6	7	in	in	ADP
sq87br88t3x	6	8	the	the	DET
sq87br88t3x	6	9	formation	formation	NOUN
sq87br88t3x	6	10	of	of	ADP
sq87br88t3x	6	11	inverted	invert	VERB
sq87br88t3x	6	12	glandular	glandular	ADJ
sq87br88t3x	6	13	units	unit	NOUN
sq87br88t3x	6	14	,	,	PUNCT
sq87br88t3x	6	15	although	although	SCONJ
sq87br88t3x	6	16	individual	individual	ADJ
sq87br88t3x	6	17	cell	cell	NOUN
sq87br88t3x	6	18	polarity	polarity	NOUN
sq87br88t3x	6	19	remains	remain	VERB
sq87br88t3x	6	20	unperturbed	unperturbed	ADJ
sq87br88t3x	6	21	.	.	PUNCT
sq87br88t3x	7	1	this	this	DET
sq87br88t3x	7	2	inversion	inversion	NOUN
sq87br88t3x	7	3	is	be	AUX
sq87br88t3x	7	4	accompanied	accompany	VERB
sq87br88t3x	7	5	by	by	ADP
sq87br88t3x	7	6	an	an	DET
sq87br88t3x	7	7	inability	inability	NOUN
sq87br88t3x	7	8	to	to	PART
sq87br88t3x	7	9	activate	activate	VERB
sq87br88t3x	7	10	rac1	rac1	PROPN
sq87br88t3x	7	11	at	at	ADP
sq87br88t3x	7	12	critical	critical	ADJ
sq87br88t3x	7	13	time	time	NOUN
sq87br88t3x	7	14	points	point	NOUN
sq87br88t3x	7	15	in	in	ADP
sq87br88t3x	7	16	cystogenesis	cystogenesis	NOUN
sq87br88t3x	7	17	and	and	CCONJ
sq87br88t3x	7	18	a	a	DET
sq87br88t3x	7	19	failure	failure	NOUN
sq87br88t3x	7	20	to	to	PART
sq87br88t3x	7	21	deposit	deposit	VERB
sq87br88t3x	7	22	laminin	laminin	PROPN
sq87br88t3x	7	23	.	.	PUNCT
sq87br88t3x	8	1	the	the	DET
sq87br88t3x	8	2	activation	activation	NOUN
sq87br88t3x	8	3	of	of	ADP
sq87br88t3x	8	4	rac1	rac1	PROPN
sq87br88t3x	8	5	,	,	PUNCT
sq87br88t3x	8	6	in	in	ADP
sq87br88t3x	8	7	a	a	DET
sq87br88t3x	8	8	time	time	NOUN
sq87br88t3x	8	9	dependent	dependent	ADJ
sq87br88t3x	8	10	manner	manner	NOUN
sq87br88t3x	8	11	,	,	PUNCT
sq87br88t3x	8	12	is	be	AUX
sq87br88t3x	8	13	sufficient	sufficient	ADJ
sq87br88t3x	8	14	to	to	PART
sq87br88t3x	8	15	recover	recover	VERB
sq87br88t3x	8	16	a	a	DET
sq87br88t3x	8	17	normal	normal	ADJ
sq87br88t3x	8	18	cyst	cyst	NOUN
sq87br88t3x	8	19	phenotype	phenotype	NOUN
sq87br88t3x	8	20	,	,	PUNCT
sq87br88t3x	8	21	as	as	ADV
sq87br88t3x	8	22	well	well	ADV
sq87br88t3x	8	23	as	as	ADP
sq87br88t3x	8	24	a	a	DET
sq87br88t3x	8	25	proper	proper	ADJ
sq87br88t3x	8	26	distribution	distribution	NOUN
sq87br88t3x	8	27	of	of	ADP
sq87br88t3x	8	28	laminin	laminin	NOUN
sq87br88t3x	8	29	to	to	PART
sq87br88t3x	8	30	support	support	VERB
sq87br88t3x	8	31	cyst	cyst	NOUN
sq87br88t3x	8	32	development	development	NOUN
sq87br88t3x	8	33	.	.	PUNCT
sq87br88t3x	9	1	both	both	PRON
sq87br88t3x	9	2	,	,	PUNCT
sq87br88t3x	9	3	rac1	rac1	PROPN
sq87br88t3x	9	4	-	-	PUNCT
sq87br88t3x	9	5	activation	activation	NOUN
sq87br88t3x	9	6	and	and	CCONJ
sq87br88t3x	9	7	laminin	laminin	NOUN
sq87br88t3x	9	8	-	-	PUNCT
sq87br88t3x	9	9	deposition	deposition	NOUN
sq87br88t3x	9	10	occur	occur	VERB
sq87br88t3x	9	11	in	in	ADP
sq87br88t3x	9	12	concert	concert	NOUN
sq87br88t3x	9	13	with	with	ADP
sq87br88t3x	9	14	matrix	matrix	NOUN
sq87br88t3x	9	15	remodeling	remodeling	NOUN
sq87br88t3x	9	16	induced	induce	VERB
sq87br88t3x	9	17	by	by	ADP
sq87br88t3x	9	18	matrix	matrix	NOUN
sq87br88t3x	9	19	metalloproteinases	metalloproteinase	NOUN
sq87br88t3x	9	20	.	.	PUNCT
sq87br88t3x	10	1	when	when	SCONJ
sq87br88t3x	10	2	arf6	arf6	PROPN
sq87br88t3x	10	3	expression	expression	NOUN
sq87br88t3x	10	4	is	be	AUX
sq87br88t3x	10	5	knocked	knock	VERB
sq87br88t3x	10	6	down	down	ADP
sq87br88t3x	10	7	in	in	ADP
sq87br88t3x	10	8	unnatural	unnatural	ADJ
sq87br88t3x	10	9	environments	environment	NOUN
sq87br88t3x	10	10	,	,	PUNCT
sq87br88t3x	10	11	such	such	ADJ
sq87br88t3x	10	12	as	as	ADP
sq87br88t3x	10	13	collagen	collagen	PROPN
sq87br88t3x	10	14	i	i	PRON
sq87br88t3x	10	15	matrix	matrix	NOUN
sq87br88t3x	10	16	,	,	PUNCT
sq87br88t3x	10	17	the	the	DET
sq87br88t3x	10	18	resulting	result	VERB
sq87br88t3x	10	19	cysts	cyst	NOUN
sq87br88t3x	10	20	exhibit	exhibit	VERB
sq87br88t3x	10	21	an	an	DET
sq87br88t3x	10	22	altered	altered	ADJ
sq87br88t3x	10	23	polarity	polarity	NOUN
sq87br88t3x	10	24	coupled	couple	VERB
sq87br88t3x	10	25	with	with	ADP
sq87br88t3x	10	26	an	an	DET
sq87br88t3x	10	27	enhanced	enhanced	ADJ
sq87br88t3x	10	28	capacity	capacity	NOUN
sq87br88t3x	10	29	to	to	PART
sq87br88t3x	10	30	adhere	adhere	VERB
sq87br88t3x	10	31	to	to	ADP
sq87br88t3x	10	32	and	and	CCONJ
sq87br88t3x	10	33	constrict	constrict	VERB
sq87br88t3x	10	34	the	the	DET
sq87br88t3x	10	35	non	non	ADJ
sq87br88t3x	10	36	-	-	ADJ
sq87br88t3x	10	37	native	native	ADJ
sq87br88t3x	10	38	matrix	matrix	NOUN
sq87br88t3x	10	39	microenvironment	microenvironment	NOUN
sq87br88t3x	10	40	.	.	PUNCT
sq87br88t3x	11	1	thus	thus	ADV
sq87br88t3x	11	2	,	,	PUNCT
sq87br88t3x	11	3	the	the	DET
sq87br88t3x	11	4	cellular	cellular	ADJ
sq87br88t3x	11	5	microenvironment	microenvironment	NOUN
sq87br88t3x	11	6	appears	appear	VERB
sq87br88t3x	11	7	to	to	PART
sq87br88t3x	11	8	markedly	markedly	ADV
sq87br88t3x	11	9	influence	influence	VERB
sq87br88t3x	11	10	the	the	DET
sq87br88t3x	11	11	glandular	glandular	ADJ
sq87br88t3x	11	12	phenotype	phenotype	NOUN
sq87br88t3x	11	13	induced	induce	VERB
sq87br88t3x	11	14	upon	upon	SCONJ
sq87br88t3x	11	15	arf6	arf6	PROPN
sq87br88t3x	11	16	depletion	depletion	NOUN
sq87br88t3x	11	17	.	.	PUNCT
sq87br88t3x	12	1	finally	finally	ADV
sq87br88t3x	12	2	,	,	PUNCT
sq87br88t3x	12	3	arf6	arf6	PROPN
sq87br88t3x	12	4	depletion	depletion	NOUN
sq87br88t3x	12	5	inhibits	inhibit	NOUN
sq87br88t3x	12	6	tubule	tubule	NOUN
sq87br88t3x	12	7	initiation	initiation	NOUN
sq87br88t3x	12	8	from	from	ADP
sq87br88t3x	12	9	renal	renal	ADJ
sq87br88t3x	12	10	cysts	cyst	NOUN
sq87br88t3x	12	11	exposed	expose	VERB
sq87br88t3x	12	12	to	to	ADP
sq87br88t3x	12	13	growth	growth	NOUN
sq87br88t3x	12	14	factors	factor	NOUN
sq87br88t3x	12	15	such	such	ADJ
sq87br88t3x	12	16	hgf	hgf	NOUN
sq87br88t3x	12	17	,	,	PUNCT
sq87br88t3x	12	18	confirming	confirm	VERB
sq87br88t3x	12	19	a	a	DET
sq87br88t3x	12	20	role	role	NOUN
sq87br88t3x	12	21	for	for	ADP
sq87br88t3x	12	22	arf6	arf6	PROPN
sq87br88t3x	12	23	in	in	ADP
sq87br88t3x	12	24	the	the	DET
sq87br88t3x	12	25	early	early	ADJ
sq87br88t3x	12	26	stages	stage	NOUN
sq87br88t3x	12	27	of	of	ADP
sq87br88t3x	12	28	tubule	tubule	NOUN
sq87br88t3x	12	29	formation	formation	NOUN
sq87br88t3x	12	30	.	.	PUNCT
sq87br88t3x	13	1	the	the	DET
sq87br88t3x	13	2	arf6	arf6	PROPN
sq87br88t3x	13	3	knockdown	knockdown	NOUN
sq87br88t3x	13	4	phenotypes	phenotype	NOUN
sq87br88t3x	13	5	described	describe	VERB
sq87br88t3x	13	6	here	here	ADV
sq87br88t3x	13	7	,	,	PUNCT
sq87br88t3x	13	8	model	model	ADJ
sq87br88t3x	13	9	histological	histological	ADJ
sq87br88t3x	13	10	phenotypes	phenotype	NOUN
sq87br88t3x	13	11	found	find	VERB
sq87br88t3x	13	12	in	in	ADP
sq87br88t3x	13	13	a	a	DET
sq87br88t3x	13	14	number	number	NOUN
sq87br88t3x	13	15	of	of	ADP
sq87br88t3x	13	16	human	human	ADJ
sq87br88t3x	13	17	diseases	disease	NOUN
sq87br88t3x	13	18	,	,	PUNCT
sq87br88t3x	13	19	particularly	particularly	ADV
sq87br88t3x	13	20	in	in	ADP
sq87br88t3x	13	21	invasive	invasive	ADJ
sq87br88t3x	13	22	cancers	cancer	NOUN
sq87br88t3x	13	23	.	.	PUNCT
sq87br88t3x	14	1	we	we	PRON
sq87br88t3x	14	2	believe	believe	VERB
sq87br88t3x	14	3	that	that	SCONJ
sq87br88t3x	14	4	the	the	DET
sq87br88t3x	14	5	role	role	NOUN
sq87br88t3x	14	6	of	of	ADP
sq87br88t3x	14	7	arf6	arf6	PROPN
sq87br88t3x	14	8	in	in	ADP
sq87br88t3x	14	9	regulating	regulate	VERB
sq87br88t3x	14	10	epithelial	epithelial	ADJ
sq87br88t3x	14	11	morphogenesis	morphogenesis	NOUN
sq87br88t3x	14	12	could	could	AUX
sq87br88t3x	14	13	be	be	AUX
sq87br88t3x	14	14	extrapolated	extrapolate	VERB
sq87br88t3x	14	15	to	to	PART
sq87br88t3x	14	16	investigate	investigate	VERB
sq87br88t3x	14	17	tissue	tissue	NOUN
sq87br88t3x	14	18	events	event	NOUN
sq87br88t3x	14	19	associated	associate	VERB
sq87br88t3x	14	20	with	with	ADP
sq87br88t3x	14	21	epithelial	epithelial	ADJ
sq87br88t3x	14	22	cancer	cancer	NOUN
sq87br88t3x	14	23	progression	progression	NOUN
sq87br88t3x	14	24	from	from	ADP
sq87br88t3x	14	25	invasion	invasion	NOUN
sq87br88t3x	14	26	to	to	ADP
sq87br88t3x	14	27	metastasis	metastasis	NOUN
sq87br88t3x	14	28	.	.	PUNCT