id sid tid token lemma pos tx31qf8849x 1 1 hemostasis hemostasis NOUN tx31qf8849x 1 2 is be AUX tx31qf8849x 1 3 maintained maintain VERB tx31qf8849x 1 4 by by ADP tx31qf8849x 1 5 a a DET tx31qf8849x 1 6 well well ADV tx31qf8849x 1 7 - - PUNCT tx31qf8849x 1 8 coordinated coordinate VERB tx31qf8849x 1 9 series series NOUN tx31qf8849x 1 10 of of ADP tx31qf8849x 1 11 vascular vascular ADJ tx31qf8849x 1 12 and and CCONJ tx31qf8849x 1 13 chemical chemical NOUN tx31qf8849x 1 14 reactions reaction NOUN tx31qf8849x 1 15 that that PRON tx31qf8849x 1 16 regulate regulate VERB tx31qf8849x 1 17 the the DET tx31qf8849x 1 18 balance balance NOUN tx31qf8849x 1 19 between between ADP tx31qf8849x 1 20 coagulation coagulation NOUN tx31qf8849x 1 21 and and CCONJ tx31qf8849x 1 22 fibrinolysis fibrinolysis NOUN tx31qf8849x 1 23 . . PUNCT tx31qf8849x 2 1 under under ADP tx31qf8849x 2 2 certain certain ADJ tx31qf8849x 2 3 pathological pathological ADJ tx31qf8849x 2 4 conditions condition NOUN tx31qf8849x 2 5 an an DET tx31qf8849x 2 6 exaggerated exaggerated ADJ tx31qf8849x 2 7 or or CCONJ tx31qf8849x 2 8 insufficiently insufficiently ADV tx31qf8849x 2 9 haemostatic haemostatic ADJ tx31qf8849x 2 10 response response NOUN tx31qf8849x 2 11 may may AUX tx31qf8849x 2 12 lead lead VERB tx31qf8849x 2 13 to to ADP tx31qf8849x 2 14 a a DET tx31qf8849x 2 15 situation situation NOUN tx31qf8849x 2 16 in in ADP tx31qf8849x 2 17 which which PRON tx31qf8849x 2 18 coagulation coagulation NOUN tx31qf8849x 2 19 / / SYM tx31qf8849x 2 20 fibrinolysis fibrinolysis NOUN tx31qf8849x 2 21 contribute contribute VERB tx31qf8849x 2 22 to to ADP tx31qf8849x 2 23 disease disease NOUN tx31qf8849x 2 24 . . PUNCT tx31qf8849x 3 1 in in ADP tx31qf8849x 3 2 the the DET tx31qf8849x 3 3 first first ADJ tx31qf8849x 3 4 part part NOUN tx31qf8849x 3 5 of of ADP tx31qf8849x 3 6 this this DET tx31qf8849x 3 7 work work NOUN tx31qf8849x 3 8 , , PUNCT tx31qf8849x 3 9 we we PRON tx31qf8849x 3 10 undertook undertake VERB tx31qf8849x 3 11 a a DET tx31qf8849x 3 12 study study NOUN tx31qf8849x 3 13 of of ADP tx31qf8849x 3 14 the the DET tx31qf8849x 3 15 function function NOUN tx31qf8849x 3 16 of of ADP tx31qf8849x 3 17 fibrinogen fibrinogen NOUN tx31qf8849x 3 18 ( ( PUNCT tx31qf8849x 3 19 fg fg PROPN tx31qf8849x 3 20 ) ) PUNCT tx31qf8849x 3 21 in in ADP tx31qf8849x 3 22 a a DET tx31qf8849x 3 23 murine murine NOUN tx31qf8849x 3 24 model model NOUN tx31qf8849x 3 25 of of ADP tx31qf8849x 3 26 acute acute ADJ tx31qf8849x 3 27 inflammation inflammation NOUN tx31qf8849x 3 28 , , PUNCT tx31qf8849x 3 29 viz viz PROPN tx31qf8849x 3 30 . . PROPN tx31qf8849x 3 31 , , PUNCT tx31qf8849x 3 32 lipopolysaccharide lipopolysaccharide PROPN tx31qf8849x 3 33 ( ( PUNCT tx31qf8849x 3 34 lps)-induced lps)-induce VERB tx31qf8849x 3 35 lethal lethal ADJ tx31qf8849x 3 36 endotoxemia endotoxemia NOUN tx31qf8849x 3 37 . . PUNCT tx31qf8849x 4 1 this this DET tx31qf8849x 4 2 study study NOUN tx31qf8849x 4 3 demonstrated demonstrate VERB tx31qf8849x 4 4 that that SCONJ tx31qf8849x 4 5 mice mouse NOUN tx31qf8849x 4 6 with with ADP tx31qf8849x 4 7 a a DET tx31qf8849x 4 8 total total ADJ tx31qf8849x 4 9 deficiency deficiency NOUN tx31qf8849x 4 10 of of ADP tx31qf8849x 4 11 fibrinogen fibrinogen NOUN tx31qf8849x 4 12 ( ( PUNCT tx31qf8849x 4 13 fg-/- fg-/- PROPN tx31qf8849x 4 14 ) ) PUNCT tx31qf8849x 4 15 presented present VERB tx31qf8849x 4 16 with with ADP tx31qf8849x 4 17 reduced reduce VERB tx31qf8849x 4 18 mortality mortality NOUN tx31qf8849x 4 19 , , PUNCT tx31qf8849x 4 20 coagulation coagulation NOUN tx31qf8849x 4 21 , , PUNCT tx31qf8849x 4 22 and and CCONJ tx31qf8849x 4 23 inflammatory inflammatory ADJ tx31qf8849x 4 24 responses response NOUN tx31qf8849x 4 25 when when SCONJ tx31qf8849x 4 26 compared compare VERB tx31qf8849x 4 27 to to ADP tx31qf8849x 4 28 their their PRON tx31qf8849x 4 29 wild wild ADJ tx31qf8849x 4 30 - - PUNCT tx31qf8849x 4 31 type type NOUN tx31qf8849x 4 32 ( ( PUNCT tx31qf8849x 4 33 wt wt PROPN tx31qf8849x 4 34 ) ) PUNCT tx31qf8849x 4 35 counterpart counterpart NOUN tx31qf8849x 4 36 . . PUNCT tx31qf8849x 5 1 the the DET tx31qf8849x 5 2 attenuated attenuated ADJ tx31qf8849x 5 3 inflammatory inflammatory ADJ tx31qf8849x 5 4 responses response NOUN tx31qf8849x 5 5 in in ADP tx31qf8849x 5 6 fg-/mice fg-/mice NOUN tx31qf8849x 5 7 correlated correlate VERB tx31qf8849x 5 8 with with ADP tx31qf8849x 5 9 a a DET tx31qf8849x 5 10 lack lack NOUN tx31qf8849x 5 11 of of ADP tx31qf8849x 5 12 fibrin fibrin NOUN tx31qf8849x 5 13 deposition deposition NOUN tx31qf8849x 5 14 in in ADP tx31qf8849x 5 15 organs organ NOUN tx31qf8849x 5 16 . . PUNCT tx31qf8849x 6 1 inflammatory inflammatory ADJ tx31qf8849x 6 2 cells cell NOUN tx31qf8849x 6 3 appeared appear VERB tx31qf8849x 6 4 early early ADV tx31qf8849x 6 5 in in ADP tx31qf8849x 6 6 the the DET tx31qf8849x 6 7 tissues tissue NOUN tx31qf8849x 6 8 of of ADP tx31qf8849x 6 9 challenged challenge VERB tx31qf8849x 6 10 wt wt PROPN tx31qf8849x 6 11 mice mouse NOUN tx31qf8849x 6 12 , , PUNCT tx31qf8849x 6 13 but but CCONJ tx31qf8849x 6 14 occurred occur VERB tx31qf8849x 6 15 at at ADP tx31qf8849x 6 16 later later ADJ tx31qf8849x 6 17 times time NOUN tx31qf8849x 6 18 in in ADP tx31qf8849x 6 19 fg-/mice fg-/mice SPACE tx31qf8849x 6 20 . . PUNCT tx31qf8849x 7 1 this this DET tx31qf8849x 7 2 delayed delay VERB tx31qf8849x 7 3 response response NOUN tx31qf8849x 7 4 in in ADP tx31qf8849x 7 5 fg-/mice fg-/mice NOUN tx31qf8849x 7 6 was be AUX tx31qf8849x 7 7 confirmed confirm VERB tx31qf8849x 7 8 by by ADP tx31qf8849x 7 9 studies study NOUN tx31qf8849x 7 10 that that PRON tx31qf8849x 7 11 showed show VERB tx31qf8849x 7 12 a a DET tx31qf8849x 7 13 strong strong ADJ tx31qf8849x 7 14 dependence dependence NOUN tx31qf8849x 7 15 on on ADP tx31qf8849x 7 16 fg fg PROPN tx31qf8849x 7 17 for for ADP tx31qf8849x 7 18 binding bind VERB tx31qf8849x 7 19 of of ADP tx31qf8849x 7 20 neutrophils neutrophil NOUN tx31qf8849x 7 21 to to ADP tx31qf8849x 7 22 endothelial endothelial ADJ tx31qf8849x 7 23 cells cell NOUN tx31qf8849x 7 24 in in ADP tx31qf8849x 7 25 the the DET tx31qf8849x 7 26 presence presence NOUN tx31qf8849x 7 27 of of ADP tx31qf8849x 7 28 lps lps PROPN tx31qf8849x 7 29 . . PUNCT tx31qf8849x 8 1 inflammatory inflammatory ADJ tx31qf8849x 8 2 cytokines cytokine NOUN tx31qf8849x 8 3 were be AUX tx31qf8849x 8 4 elevated elevate VERB tx31qf8849x 8 5 in in ADP tx31qf8849x 8 6 both both DET tx31qf8849x 8 7 genotypes genotype NOUN tx31qf8849x 8 8 , , PUNCT tx31qf8849x 8 9 however however ADV tx31qf8849x 8 10 their their PRON tx31qf8849x 8 11 levels level NOUN tx31qf8849x 8 12 were be AUX tx31qf8849x 8 13 generally generally ADV tx31qf8849x 8 14 lower low ADJ tx31qf8849x 8 15 at at ADP tx31qf8849x 8 16 early early ADJ tx31qf8849x 8 17 times time NOUN tx31qf8849x 8 18 in in ADP tx31qf8849x 8 19 fg-/- fg-/- NOUN tx31qf8849x 8 20 . . PUNCT tx31qf8849x 9 1 therefore therefore ADV tx31qf8849x 9 2 , , PUNCT tx31qf8849x 9 3 a a DET tx31qf8849x 9 4 fg fg PROPN tx31qf8849x 9 5 deficiency deficiency NOUN tx31qf8849x 9 6 enhances enhance VERB tx31qf8849x 9 7 survival survival NOUN tx31qf8849x 9 8 from from ADP tx31qf8849x 9 9 lethal lethal ADJ tx31qf8849x 9 10 endotoxemia endotoxemia NOUN tx31qf8849x 9 11 through through ADP tx31qf8849x 9 12 attenuation attenuation NOUN tx31qf8849x 9 13 of of ADP tx31qf8849x 9 14 inflammatory inflammatory ADJ tx31qf8849x 9 15 responses response NOUN tx31qf8849x 9 16 that that PRON tx31qf8849x 9 17 result result VERB tx31qf8849x 9 18 from from ADP tx31qf8849x 9 19 reduced reduced ADJ tx31qf8849x 9 20 leukocyte leukocyte NOUN tx31qf8849x 9 21 infiltration infiltration NOUN tx31qf8849x 9 22 to to ADP tx31qf8849x 9 23 the the DET tx31qf8849x 9 24 inflammatory inflammatory ADJ tx31qf8849x 9 25 foci focus NOUN tx31qf8849x 9 26 , , PUNCT tx31qf8849x 9 27 and and CCONJ tx31qf8849x 9 28 , , PUNCT tx31qf8849x 9 29 from from ADP tx31qf8849x 9 30 downregulation downregulation NOUN tx31qf8849x 9 31 of of ADP tx31qf8849x 9 32 chemokine chemokine NOUN tx31qf8849x 9 33 / / SYM tx31qf8849x 9 34 cytokine cytokine NOUN tx31qf8849x 9 35 expression expression NOUN tx31qf8849x 9 36 . . PUNCT tx31qf8849x 10 1 our our PRON tx31qf8849x 10 2 results result NOUN tx31qf8849x 10 3 suggest suggest VERB tx31qf8849x 10 4 that that SCONJ tx31qf8849x 10 5 fibrin(ogen fibrin(ogen PROPN tx31qf8849x 10 6 ) ) PUNCT tx31qf8849x 10 7 plays play VERB tx31qf8849x 10 8 an an DET tx31qf8849x 10 9 important important ADJ tx31qf8849x 10 10 role role NOUN tx31qf8849x 10 11 as as ADP tx31qf8849x 10 12 an an DET tx31qf8849x 10 13 early early ADJ tx31qf8849x 10 14 mediator mediator NOUN tx31qf8849x 10 15 in in ADP tx31qf8849x 10 16 the the DET tx31qf8849x 10 17 cross cross NOUN tx31qf8849x 10 18 - - NOUN tx31qf8849x 10 19 talk talk NOUN tx31qf8849x 10 20 between between ADP tx31qf8849x 10 21 coagulation coagulation NOUN tx31qf8849x 10 22 and and CCONJ tx31qf8849x 10 23 inflammation inflammation NOUN tx31qf8849x 10 24 . . PUNCT tx31qf8849x 11 1 in in ADP tx31qf8849x 11 2 the the DET tx31qf8849x 11 3 second second ADJ tx31qf8849x 11 4 part part NOUN tx31qf8849x 11 5 of of ADP tx31qf8849x 11 6 this this DET tx31qf8849x 11 7 dissertation dissertation NOUN tx31qf8849x 11 8 , , PUNCT tx31qf8849x 11 9 we we PRON tx31qf8849x 11 10 utilized utilize VERB tx31qf8849x 11 11 a a DET tx31qf8849x 11 12 biochemical biochemical ADJ tx31qf8849x 11 13 approach approach NOUN tx31qf8849x 11 14 to to PART tx31qf8849x 11 15 study study VERB tx31qf8849x 11 16 the the DET tx31qf8849x 11 17 role role NOUN tx31qf8849x 11 18 of of ADP tx31qf8849x 11 19 plasminogen plasminogen NOUN tx31qf8849x 11 20 ( ( PUNCT tx31qf8849x 11 21 pg pg PROPN tx31qf8849x 11 22 ) ) PUNCT tx31qf8849x 11 23 in in ADP tx31qf8849x 11 24 the the DET tx31qf8849x 11 25 pathogenic pathogenic ADJ tx31qf8849x 11 26 mechanisms mechanism NOUN tx31qf8849x 11 27 of of ADP tx31qf8849x 11 28 group group NOUN tx31qf8849x 11 29 a a DET tx31qf8849x 11 30 streptreptococcus streptreptococcus PROPN tx31qf8849x 11 31 ( ( PUNCT tx31qf8849x 11 32 gas gas NOUN tx31qf8849x 11 33 ) ) PUNCT tx31qf8849x 11 34 . . PUNCT tx31qf8849x 12 1 gas gas NOUN tx31qf8849x 12 2 is be AUX tx31qf8849x 12 3 the the DET tx31qf8849x 12 4 etiologic etiologic ADJ tx31qf8849x 12 5 agent agent NOUN tx31qf8849x 12 6 responsible responsible ADJ tx31qf8849x 12 7 for for ADP tx31qf8849x 12 8 a a DET tx31qf8849x 12 9 number number NOUN tx31qf8849x 12 10 of of ADP tx31qf8849x 12 11 human human ADJ tx31qf8849x 12 12 diseases disease NOUN tx31qf8849x 12 13 that that PRON tx31qf8849x 12 14 range range VERB tx31qf8849x 12 15 from from ADP tx31qf8849x 12 16 common common ADJ tx31qf8849x 12 17 pharyngitis pharyngitis NOUN tx31qf8849x 12 18 to to ADP tx31qf8849x 12 19 severe severe ADJ tx31qf8849x 12 20 infections infection NOUN tx31qf8849x 12 21 . . PUNCT tx31qf8849x 13 1 streptokinase streptokinase PROPN tx31qf8849x 13 2 ( ( PUNCT tx31qf8849x 13 3 sk sk PROPN tx31qf8849x 13 4 ) ) PUNCT tx31qf8849x 13 5 is be AUX tx31qf8849x 13 6 a a DET tx31qf8849x 13 7 414 414 NUM tx31qf8849x 13 8 amino amino NOUN tx31qf8849x 13 9 acid acid NOUN tx31qf8849x 13 10 protein protein NOUN tx31qf8849x 13 11 secreted secrete VERB tx31qf8849x 13 12 by by ADP tx31qf8849x 13 13 several several ADJ tx31qf8849x 13 14 streptococcal streptococcal ADJ tx31qf8849x 13 15 species specie NOUN tx31qf8849x 13 16 , , PUNCT tx31qf8849x 13 17 and and CCONJ tx31qf8849x 13 18 an an DET tx31qf8849x 13 19 efficient efficient ADJ tx31qf8849x 13 20 activator activator NOUN tx31qf8849x 13 21 of of ADP tx31qf8849x 13 22 pg pg PROPN tx31qf8849x 13 23 . . PUNCT tx31qf8849x 14 1 interestingly interestingly ADV tx31qf8849x 14 2 , , PUNCT tx31qf8849x 14 3 sk sk INTJ tx31qf8849x 14 4 is be AUX tx31qf8849x 14 5 not not PART tx31qf8849x 14 6 an an DET tx31qf8849x 14 7 enzyme enzyme NOUN tx31qf8849x 14 8 ; ; PUNCT tx31qf8849x 14 9 it it PRON tx31qf8849x 14 10 activates activate VERB tx31qf8849x 14 11 pg pg PROPN tx31qf8849x 14 12 indirectly indirectly ADV tx31qf8849x 14 13 by by ADP tx31qf8849x 14 14 the the DET tx31qf8849x 14 15 formation formation NOUN tx31qf8849x 14 16 of of ADP tx31qf8849x 14 17 a a DET tx31qf8849x 14 18 1:1 1:1 NUM tx31qf8849x 14 19 complex complex NOUN tx31qf8849x 14 20 with with ADP tx31qf8849x 14 21 pg pg PROPN tx31qf8849x 14 22 . . PUNCT tx31qf8849x 15 1 furthermore furthermore ADV tx31qf8849x 15 2 , , PUNCT tx31qf8849x 15 3 pg pg PROPN tx31qf8849x 15 4 activation activation NOUN tx31qf8849x 15 5 by by ADP tx31qf8849x 15 6 sk sk NOUN tx31qf8849x 15 7 is be AUX tx31qf8849x 15 8 highly highly ADV tx31qf8849x 15 9 species specie NOUN tx31qf8849x 15 10 specific specific ADJ tx31qf8849x 15 11 with with ADP tx31qf8849x 15 12 activity activity NOUN tx31qf8849x 15 13 towards towards ADP tx31qf8849x 15 14 human human ADJ tx31qf8849x 15 15 pg pg PROPN tx31qf8849x 15 16 ( ( PUNCT tx31qf8849x 15 17 hpg hpg PROPN tx31qf8849x 15 18 ) ) PUNCT tx31qf8849x 15 19 , , PUNCT tx31qf8849x 15 20 but but CCONJ tx31qf8849x 15 21 exhibiting exhibit VERB tx31qf8849x 15 22 no no DET tx31qf8849x 15 23 activity activity NOUN tx31qf8849x 15 24 against against ADP tx31qf8849x 15 25 mouse mouse NOUN tx31qf8849x 15 26 plasminogen plasminogen NOUN tx31qf8849x 15 27 ( ( PUNCT tx31qf8849x 15 28 mpg mpg NOUN tx31qf8849x 15 29 ) ) PUNCT tx31qf8849x 15 30 . . PUNCT tx31qf8849x 16 1 in in ADP tx31qf8849x 16 2 an an DET tx31qf8849x 16 3 attempt attempt NOUN tx31qf8849x 16 4 to to PART tx31qf8849x 16 5 define define VERB tx31qf8849x 16 6 which which DET tx31qf8849x 16 7 amino amino NOUN tx31qf8849x 16 8 acid acid NOUN tx31qf8849x 16 9 regions region NOUN tx31qf8849x 16 10 within within ADP tx31qf8849x 16 11 pg pg PROPN tx31qf8849x 16 12 may may AUX tx31qf8849x 16 13 account account VERB tx31qf8849x 16 14 for for ADP tx31qf8849x 16 15 the the DET tx31qf8849x 16 16 species specie NOUN tx31qf8849x 16 17 specificity specificity NOUN tx31qf8849x 16 18 of of ADP tx31qf8849x 16 19 sk sk PROPN tx31qf8849x 16 20 , , PUNCT tx31qf8849x 16 21 several several ADJ tx31qf8849x 16 22 mutants mutant NOUN tx31qf8849x 16 23 , , PUNCT tx31qf8849x 16 24 and and CCONJ tx31qf8849x 16 25 chimeric chimeric ADJ tx31qf8849x 16 26 mouse mouse NOUN tx31qf8849x 16 27 - - PUNCT tx31qf8849x 16 28 human human ADJ tx31qf8849x 16 29 pg pg PROPN tx31qf8849x 16 30 constructs construct NOUN tx31qf8849x 16 31 were be AUX tx31qf8849x 16 32 generated generate VERB tx31qf8849x 16 33 . . PUNCT tx31qf8849x 17 1 the the DET tx31qf8849x 17 2 hpg hpg PROPN tx31qf8849x 17 3 light light PROPN tx31qf8849x 17 4 chain chain NOUN tx31qf8849x 17 5 ( ( PUNCT tx31qf8849x 17 6 hl hl INTJ tx31qf8849x 17 7 ) ) PUNCT tx31qf8849x 17 8 was be AUX tx31qf8849x 17 9 identified identify VERB tx31qf8849x 17 10 as as ADP tx31qf8849x 17 11 the the DET tx31qf8849x 17 12 region region NOUN tx31qf8849x 17 13 responsible responsible ADJ tx31qf8849x 17 14 for for ADP tx31qf8849x 17 15 sk sk X tx31qf8849x 17 16 sensitivity sensitivity NOUN tx31qf8849x 17 17 , , PUNCT tx31qf8849x 17 18 specifically specifically ADV tx31qf8849x 17 19 the the DET tx31qf8849x 17 20 amino amino NOUN tx31qf8849x 17 21 acid acid NOUN tx31qf8849x 17 22 sequences sequence NOUN tx31qf8849x 17 23 encoded encode VERB tx31qf8849x 17 24 by by ADP tx31qf8849x 17 25 exons exon NOUN tx31qf8849x 17 26 16 16 NUM tx31qf8849x 17 27 and and CCONJ tx31qf8849x 17 28 18 18 NUM tx31qf8849x 17 29 . . PUNCT tx31qf8849x 18 1 in in ADP tx31qf8849x 18 2 addition addition NOUN tx31qf8849x 18 3 , , PUNCT tx31qf8849x 18 4 surface surface PROPN tx31qf8849x 18 5 plasmon plasmon NOUN tx31qf8849x 18 6 resonance resonance NOUN tx31qf8849x 18 7 ( ( PUNCT tx31qf8849x 18 8 spr spr ADJ tx31qf8849x 18 9 ) ) PUNCT tx31qf8849x 18 10 experiments experiment NOUN tx31qf8849x 18 11 demonstrated demonstrate VERB tx31qf8849x 18 12 high high ADJ tx31qf8849x 18 13 affinity affinity NOUN tx31qf8849x 18 14 binding bind VERB tx31qf8849x 18 15 between between ADP tx31qf8849x 18 16 all all DET tx31qf8849x 18 17 pg pg PROPN tx31qf8849x 18 18 variants variant NOUN tx31qf8849x 18 19 and and CCONJ tx31qf8849x 18 20 sk sk PROPN tx31qf8849x 18 21 , , PUNCT tx31qf8849x 18 22 including include VERB tx31qf8849x 18 23 mpg mpg NOUN tx31qf8849x 18 24 , , PUNCT tx31qf8849x 18 25 indicating indicate VERB tx31qf8849x 18 26 that that SCONJ tx31qf8849x 18 27 sk sk PROPN tx31qf8849x 18 28 has have VERB tx31qf8849x 18 29 the the DET tx31qf8849x 18 30 ability ability NOUN tx31qf8849x 18 31 to to PART tx31qf8849x 18 32 form form VERB tx31qf8849x 18 33 ' ' PUNCT tx31qf8849x 18 34 catalytic catalytic ADJ tx31qf8849x 18 35 complexes complex NOUN tx31qf8849x 18 36 ' ' PUNCT tx31qf8849x 18 37 in in ADP tx31qf8849x 18 38 a a DET tx31qf8849x 18 39 non non ADJ tx31qf8849x 18 40 - - ADJ tx31qf8849x 18 41 species species ADJ tx31qf8849x 18 42 specific specific ADJ tx31qf8849x 18 43 manner manner NOUN tx31qf8849x 18 44 . . PUNCT tx31qf8849x 19 1 however however ADV tx31qf8849x 19 2 , , PUNCT tx31qf8849x 19 3 no no DET tx31qf8849x 19 4 active active ADJ tx31qf8849x 19 5 site site NOUN tx31qf8849x 19 6 is be AUX tx31qf8849x 19 7 formed form VERB tx31qf8849x 19 8 within within ADP tx31qf8849x 19 9 the the DET tx31qf8849x 19 10 moiety moiety NOUN tx31qf8849x 19 11 of of ADP tx31qf8849x 19 12 the the DET tx31qf8849x 19 13 activator activator NOUN tx31qf8849x 19 14 complex complex NOUN tx31qf8849x 19 15 . . PUNCT tx31qf8849x 20 1 in in ADP tx31qf8849x 20 2 summary summary NOUN tx31qf8849x 20 3 , , PUNCT tx31qf8849x 20 4 we we PRON tx31qf8849x 20 5 identified identify VERB tx31qf8849x 20 6 the the DET tx31qf8849x 20 7 loci locus NOUN tx31qf8849x 20 8 within within ADP tx31qf8849x 20 9 hpg hpg NOUN tx31qf8849x 20 10 that that PRON tx31qf8849x 20 11 productively productively ADV tx31qf8849x 20 12 interacts interact VERB tx31qf8849x 20 13 with with ADP tx31qf8849x 20 14 sk sk PROPN tx31qf8849x 20 15 . . PUNCT tx31qf8849x 21 1 the the DET tx31qf8849x 21 2 data datum NOUN tx31qf8849x 21 3 generated generate VERB tx31qf8849x 21 4 herein herein ADV tx31qf8849x 21 5 presents present VERB tx31qf8849x 21 6 novel novel ADJ tx31qf8849x 21 7 insights insight NOUN tx31qf8849x 21 8 for for ADP tx31qf8849x 21 9 the the DET tx31qf8849x 21 10 understanding understanding NOUN tx31qf8849x 21 11 of of ADP tx31qf8849x 21 12 the the DET tx31qf8849x 21 13 activation activation NOUN tx31qf8849x 21 14 mechanism mechanism NOUN tx31qf8849x 21 15 of of ADP tx31qf8849x 21 16 hpg hpg NOUN tx31qf8849x 21 17 by by ADP tx31qf8849x 21 18 sk sk PROPN tx31qf8849x 21 19 . . PUNCT