id	sid	tid	token	lemma	pos
ww72b853q40	1	1	bacterial	bacterial	ADJ
ww72b853q40	1	2	resistance	resistance	NOUN
ww72b853q40	1	3	to	to	ADP
ww72b853q40	1	4	antibiotics	antibiotic	NOUN
ww72b853q40	1	5	is	be	AUX
ww72b853q40	1	6	becoming	become	VERB
ww72b853q40	1	7	increasingly	increasingly	ADV
ww72b853q40	1	8	prevalent	prevalent	ADJ
ww72b853q40	1	9	and	and	CCONJ
ww72b853q40	1	10	dictates	dictate	VERB
ww72b853q40	1	11	a	a	DET
ww72b853q40	1	12	desperate	desperate	ADJ
ww72b853q40	1	13	need	need	NOUN
ww72b853q40	1	14	for	for	ADP
ww72b853q40	1	15	new	new	ADJ
ww72b853q40	1	16	therapies	therapy	NOUN
ww72b853q40	1	17	.	.	PUNCT
ww72b853q40	2	1	a	a	DET
ww72b853q40	2	2	means	means	NOUN
ww72b853q40	2	3	of	of	ADP
ww72b853q40	2	4	fighting	fight	VERB
ww72b853q40	2	5	this	this	DET
ww72b853q40	2	6	resistance	resistance	NOUN
ww72b853q40	2	7	is	be	AUX
ww72b853q40	2	8	through	through	ADP
ww72b853q40	2	9	the	the	DET
ww72b853q40	2	10	exploitation	exploitation	NOUN
ww72b853q40	2	11	of	of	ADP
ww72b853q40	2	12	microbial	microbial	ADJ
ww72b853q40	2	13	iron	iron	NOUN
ww72b853q40	2	14	uptake	uptake	NOUN
ww72b853q40	2	15	.	.	PUNCT
ww72b853q40	3	1	in	in	ADP
ww72b853q40	3	2	order	order	NOUN
ww72b853q40	3	3	to	to	PART
ww72b853q40	3	4	obtain	obtain	VERB
ww72b853q40	3	5	this	this	DET
ww72b853q40	3	6	necessary	necessary	ADJ
ww72b853q40	3	7	nutrient	nutrient	NOUN
ww72b853q40	3	8	,	,	PUNCT
ww72b853q40	3	9	bacteria	bacteria	NOUN
ww72b853q40	3	10	synthesize	synthesize	VERB
ww72b853q40	3	11	a	a	DET
ww72b853q40	3	12	plethora	plethora	NOUN
ww72b853q40	3	13	of	of	ADP
ww72b853q40	3	14	low	low	ADJ
ww72b853q40	3	15	molecular	molecular	ADJ
ww72b853q40	3	16	weight	weight	NOUN
ww72b853q40	3	17	iron	iron	NOUN
ww72b853q40	3	18	chelators	chelator	NOUN
ww72b853q40	3	19	known	know	VERB
ww72b853q40	3	20	as	as	ADP
ww72b853q40	3	21	siderophores	siderophore	NOUN
ww72b853q40	3	22	.	.	PUNCT
ww72b853q40	4	1	while	while	SCONJ
ww72b853q40	4	2	drugs	drug	NOUN
ww72b853q40	4	3	can	can	AUX
ww72b853q40	4	4	be	be	AUX
ww72b853q40	4	5	attached	attach	VERB
ww72b853q40	4	6	to	to	ADP
ww72b853q40	4	7	these	these	DET
ww72b853q40	4	8	molecules	molecule	NOUN
ww72b853q40	4	9	and	and	CCONJ
ww72b853q40	4	10	actively	actively	ADV
ww72b853q40	4	11	transported	transport	VERB
ww72b853q40	4	12	into	into	ADP
ww72b853q40	4	13	cells	cell	NOUN
ww72b853q40	4	14	in	in	ADP
ww72b853q40	4	15	a	a	DET
ww72b853q40	4	16	'	'	PUNCT
ww72b853q40	4	17	trojan	trojan	NOUN
ww72b853q40	4	18	horse	horse	NOUN
ww72b853q40	4	19	'	'	PUNCT
ww72b853q40	4	20	approach	approach	NOUN
ww72b853q40	4	21	,	,	PUNCT
ww72b853q40	4	22	activity	activity	NOUN
ww72b853q40	4	23	is	be	AUX
ww72b853q40	4	24	often	often	ADV
ww72b853q40	4	25	lost	lose	VERB
ww72b853q40	4	26	when	when	SCONJ
ww72b853q40	4	27	the	the	DET
ww72b853q40	4	28	target	target	NOUN
ww72b853q40	4	29	is	be	AUX
ww72b853q40	4	30	present	present	ADJ
ww72b853q40	4	31	in	in	ADP
ww72b853q40	4	32	the	the	DET
ww72b853q40	4	33	cytoplasm	cytoplasm	NOUN
ww72b853q40	4	34	.	.	PUNCT
ww72b853q40	5	1	as	as	SCONJ
ww72b853q40	5	2	these	these	DET
ww72b853q40	5	3	drugs	drug	NOUN
ww72b853q40	5	4	no	no	ADV
ww72b853q40	5	5	longer	long	ADV
ww72b853q40	5	6	reach	reach	VERB
ww72b853q40	5	7	their	their	PRON
ww72b853q40	5	8	target	target	NOUN
ww72b853q40	5	9	or	or	CCONJ
ww72b853q40	5	10	do	do	AUX
ww72b853q40	5	11	not	not	PART
ww72b853q40	5	12	bind	bind	VERB
ww72b853q40	5	13	correctly	correctly	ADV
ww72b853q40	5	14	,	,	PUNCT
ww72b853q40	5	15	the	the	DET
ww72b853q40	5	16	incorporation	incorporation	NOUN
ww72b853q40	5	17	of	of	ADP
ww72b853q40	5	18	a	a	DET
ww72b853q40	5	19	releasable	releasable	NOUN
ww72b853q40	5	20	linker	linker	NOUN
ww72b853q40	5	21	between	between	ADP
ww72b853q40	5	22	the	the	DET
ww72b853q40	5	23	siderophore	siderophore	NOUN
ww72b853q40	5	24	and	and	CCONJ
ww72b853q40	5	25	antibiotic	antibiotic	ADJ
ww72b853q40	5	26	may	may	AUX
ww72b853q40	5	27	restore	restore	VERB
ww72b853q40	5	28	activity	activity	NOUN
ww72b853q40	5	29	and	and	CCONJ
ww72b853q40	5	30	circumvent	circumvent	VERB
ww72b853q40	5	31	resistance	resistance	NOUN
ww72b853q40	5	32	due	due	ADP
ww72b853q40	5	33	to	to	ADP
ww72b853q40	5	34	decreased	decrease	VERB
ww72b853q40	5	35	permeability	permeability	NOUN
ww72b853q40	5	36	of	of	ADP
ww72b853q40	5	37	the	the	DET
ww72b853q40	5	38	bacterial	bacterial	ADJ
ww72b853q40	5	39	outer	outer	ADJ
ww72b853q40	5	40	membrane	membrane	NOUN
ww72b853q40	5	41	.	.	PUNCT
ww72b853q40	6	1	in	in	ADP
ww72b853q40	6	2	this	this	DET
ww72b853q40	6	3	thesis	thesis	NOUN
ww72b853q40	6	4	,	,	PUNCT
ww72b853q40	6	5	work	work	VERB
ww72b853q40	6	6	towards	towards	ADP
ww72b853q40	6	7	the	the	DET
ww72b853q40	6	8	production	production	NOUN
ww72b853q40	6	9	of	of	ADP
ww72b853q40	6	10	siderophore	siderophore	NOUN
ww72b853q40	6	11	-	-	PUNCT
ww72b853q40	6	12	drug	drug	NOUN
ww72b853q40	6	13	-	-	PUNCT
ww72b853q40	6	14	conjugates	conjugate	NOUN
ww72b853q40	6	15	containing	contain	VERB
ww72b853q40	6	16	nitroreductase	nitroreductase	ADV
ww72b853q40	6	17	-	-	PUNCT
ww72b853q40	6	18	triggered	trigger	VERB
ww72b853q40	6	19	linkers	linker	NOUN
ww72b853q40	6	20	is	be	AUX
ww72b853q40	6	21	discussed	discuss	VERB
ww72b853q40	6	22	.	.	PUNCT
ww72b853q40	7	1	in	in	ADP
ww72b853q40	7	2	chapter	chapter	NOUN
ww72b853q40	7	3	2	2	NUM
ww72b853q40	7	4	,	,	PUNCT
ww72b853q40	7	5	the	the	DET
ww72b853q40	7	6	design	design	NOUN
ww72b853q40	7	7	and	and	CCONJ
ww72b853q40	7	8	syntheses	synthesis	NOUN
ww72b853q40	7	9	of	of	ADP
ww72b853q40	7	10	linkers	linker	NOUN
ww72b853q40	7	11	hypothesized	hypothesize	VERB
ww72b853q40	7	12	to	to	PART
ww72b853q40	7	13	be	be	AUX
ww72b853q40	7	14	reduced	reduce	VERB
ww72b853q40	7	15	and	and	CCONJ
ww72b853q40	7	16	cyclized	cyclize	VERB
ww72b853q40	7	17	by	by	ADP
ww72b853q40	7	18	bacterial	bacterial	ADJ
ww72b853q40	7	19	nitroreductase	nitroreductase	ADJ
ww72b853q40	7	20	enzymes	enzyme	NOUN
ww72b853q40	7	21	are	be	AUX
ww72b853q40	7	22	described	describe	VERB
ww72b853q40	7	23	.	.	PUNCT
ww72b853q40	8	1	initially	initially	ADV
ww72b853q40	8	2	,	,	PUNCT
ww72b853q40	8	3	test	test	NOUN
ww72b853q40	8	4	molecules	molecule	NOUN
ww72b853q40	8	5	were	be	AUX
ww72b853q40	8	6	synthesized	synthesize	VERB
ww72b853q40	8	7	and	and	CCONJ
ww72b853q40	8	8	reduced	reduce	VERB
ww72b853q40	8	9	to	to	PART
ww72b853q40	8	10	demonstrate	demonstrate	VERB
ww72b853q40	8	11	the	the	DET
ww72b853q40	8	12	feasibility	feasibility	NOUN
ww72b853q40	8	13	of	of	ADP
ww72b853q40	8	14	triggered	trigger	VERB
ww72b853q40	8	15	drug	drug	NOUN
ww72b853q40	8	16	release	release	NOUN
ww72b853q40	8	17	.	.	PUNCT
ww72b853q40	9	1	after	after	ADP
ww72b853q40	9	2	this	this	DET
ww72b853q40	9	3	proof	proof	NOUN
ww72b853q40	9	4	of	of	ADP
ww72b853q40	9	5	principle	principle	NOUN
ww72b853q40	9	6	,	,	PUNCT
ww72b853q40	9	7	a	a	DET
ww72b853q40	9	8	first	first	ADJ
ww72b853q40	9	9	generation	generation	NOUN
ww72b853q40	9	10	linker	linker	NOUN
ww72b853q40	9	11	was	be	AUX
ww72b853q40	9	12	prepared	prepare	VERB
ww72b853q40	9	13	,	,	PUNCT
ww72b853q40	9	14	however	however	ADV
ww72b853q40	9	15	a	a	DET
ww72b853q40	9	16	nitroreductase	nitroreductase	ADJ
ww72b853q40	9	17	assay	assay	NOUN
ww72b853q40	9	18	suggested	suggest	VERB
ww72b853q40	9	19	that	that	SCONJ
ww72b853q40	9	20	linkers	linker	NOUN
ww72b853q40	9	21	with	with	ADP
ww72b853q40	9	22	adjusted	adjusted	ADJ
ww72b853q40	9	23	reduction	reduction	NOUN
ww72b853q40	9	24	potential	potential	NOUN
ww72b853q40	9	25	might	might	AUX
ww72b853q40	9	26	be	be	AUX
ww72b853q40	9	27	necessary	necessary	ADJ
ww72b853q40	9	28	for	for	ADP
ww72b853q40	9	29	drug	drug	NOUN
ww72b853q40	9	30	release	release	NOUN
ww72b853q40	9	31	.	.	PUNCT
ww72b853q40	10	1	therefore	therefore	ADV
ww72b853q40	10	2	,	,	PUNCT
ww72b853q40	10	3	additional	additional	ADJ
ww72b853q40	10	4	molecules	molecule	NOUN
ww72b853q40	10	5	were	be	AUX
ww72b853q40	10	6	synthesized	synthesize	VERB
ww72b853q40	10	7	and	and	CCONJ
ww72b853q40	10	8	the	the	DET
ww72b853q40	10	9	three	three	NUM
ww72b853q40	10	10	prepared	prepared	ADJ
ww72b853q40	10	11	linkers	linker	NOUN
ww72b853q40	10	12	were	be	AUX
ww72b853q40	10	13	coupled	couple	VERB
ww72b853q40	10	14	to	to	ADP
ww72b853q40	10	15	ciprofloxacin	ciprofloxacin	NOUN
ww72b853q40	10	16	to	to	PART
ww72b853q40	10	17	form	form	VERB
ww72b853q40	10	18	linker	linker	NOUN
ww72b853q40	10	19	-	-	PUNCT
ww72b853q40	10	20	drug	drug	NOUN
ww72b853q40	10	21	conjugates	conjugate	NOUN
ww72b853q40	10	22	.	.	PUNCT
ww72b853q40	11	1	biological	biological	ADJ
ww72b853q40	11	2	testing	testing	NOUN
ww72b853q40	11	3	was	be	AUX
ww72b853q40	11	4	completed	complete	VERB
ww72b853q40	11	5	for	for	ADP
ww72b853q40	11	6	several	several	ADJ
ww72b853q40	11	7	synthesized	synthesized	ADJ
ww72b853q40	11	8	molecules	molecule	NOUN
ww72b853q40	11	9	and	and	CCONJ
ww72b853q40	11	10	dinitro	dinitro	ADJ
ww72b853q40	11	11	containing	contain	VERB
ww72b853q40	11	12	compounds	compound	NOUN
ww72b853q40	11	13	showed	show	VERB
ww72b853q40	11	14	moderate	moderate	ADJ
ww72b853q40	11	15	to	to	ADP
ww72b853q40	11	16	strong	strong	ADJ
ww72b853q40	11	17	activity	activity	NOUN
ww72b853q40	11	18	against	against	ADP
ww72b853q40	11	19	m.	m.	PROPN
ww72b853q40	11	20	vaccae	vaccae	PROPN
ww72b853q40	11	21	and	and	CCONJ
ww72b853q40	11	22	m.	m.	NOUN
ww72b853q40	11	23	tuberculosis	tuberculosis	NOUN
ww72b853q40	11	24	.	.	PUNCT
ww72b853q40	12	1	in	in	ADP
ww72b853q40	12	2	chapter	chapter	NOUN
ww72b853q40	12	3	3	3	NUM
ww72b853q40	12	4	the	the	DET
ww72b853q40	12	5	production	production	NOUN
ww72b853q40	12	6	of	of	ADP
ww72b853q40	12	7	a	a	DET
ww72b853q40	12	8	mixed	mixed	ADJ
ww72b853q40	12	9	-	-	PUNCT
ww72b853q40	12	10	ligand	ligand	NOUN
ww72b853q40	12	11	siderophore	siderophore	NOUN
ww72b853q40	12	12	and	and	CCONJ
ww72b853q40	12	13	attempts	attempt	VERB
ww72b853q40	12	14	at	at	ADP
ww72b853q40	12	15	preparing	prepare	VERB
ww72b853q40	12	16	siderophore	siderophore	NOUN
ww72b853q40	12	17	-	-	PUNCT
ww72b853q40	12	18	drug	drug	NOUN
ww72b853q40	12	19	conjugates	conjugate	NOUN
ww72b853q40	12	20	are	be	AUX
ww72b853q40	12	21	described	describe	VERB
ww72b853q40	12	22	.	.	PUNCT
ww72b853q40	13	1	many	many	ADJ
ww72b853q40	13	2	conditions	condition	NOUN
ww72b853q40	13	3	were	be	AUX
ww72b853q40	13	4	employed	employ	VERB
ww72b853q40	13	5	unsuccessfully	unsuccessfully	ADV
ww72b853q40	13	6	to	to	PART
ww72b853q40	13	7	couple	couple	VERB
ww72b853q40	13	8	the	the	DET
ww72b853q40	13	9	siderophore	siderophore	NOUN
ww72b853q40	13	10	and	and	CCONJ
ww72b853q40	13	11	the	the	DET
ww72b853q40	13	12	linker	linker	NOUN
ww72b853q40	13	13	-	-	PUNCT
ww72b853q40	13	14	drug	drug	NOUN
ww72b853q40	13	15	conjugates	conjugate	NOUN
ww72b853q40	13	16	.	.	PUNCT
ww72b853q40	14	1	currently	currently	ADV
ww72b853q40	14	2	,	,	PUNCT
ww72b853q40	14	3	a	a	DET
ww72b853q40	14	4	new	new	ADJ
ww72b853q40	14	5	pathway	pathway	NOUN
ww72b853q40	14	6	is	be	AUX
ww72b853q40	14	7	underway	underway	ADJ
ww72b853q40	14	8	with	with	ADP
ww72b853q40	14	9	the	the	DET
ww72b853q40	14	10	hope	hope	NOUN
ww72b853q40	14	11	that	that	SCONJ
ww72b853q40	14	12	it	it	PRON
ww72b853q40	14	13	will	will	AUX
ww72b853q40	14	14	be	be	AUX
ww72b853q40	14	15	successful	successful	ADJ
ww72b853q40	14	16	in	in	ADP
ww72b853q40	14	17	the	the	DET
ww72b853q40	14	18	formation	formation	NOUN
ww72b853q40	14	19	of	of	ADP
ww72b853q40	14	20	siderophore	siderophore	NOUN
ww72b853q40	14	21	-	-	PUNCT
ww72b853q40	14	22	drug	drug	NOUN
ww72b853q40	14	23	conjugates	conjugate	NOUN
ww72b853q40	14	24	.	.	PUNCT
ww72b853q40	15	1	further	further	ADJ
ww72b853q40	15	2	studies	study	NOUN
ww72b853q40	15	3	are	be	AUX
ww72b853q40	15	4	required	require	VERB
ww72b853q40	15	5	to	to	PART
ww72b853q40	15	6	see	see	VERB
ww72b853q40	15	7	if	if	SCONJ
ww72b853q40	15	8	nitroreductase	nitroreductase	ADV
ww72b853q40	15	9	-	-	PUNCT
ww72b853q40	15	10	triggered	trigger	VERB
ww72b853q40	15	11	linkers	linker	NOUN
ww72b853q40	15	12	in	in	ADP
ww72b853q40	15	13	siderophore	siderophore	NOUN
ww72b853q40	15	14	-	-	PUNCT
ww72b853q40	15	15	drug	drug	NOUN
ww72b853q40	15	16	conjugates	conjugate	NOUN
ww72b853q40	15	17	will	will	AUX
ww72b853q40	15	18	create	create	VERB
ww72b853q40	15	19	effective	effective	ADJ
ww72b853q40	15	20	antibacterial	antibacterial	ADJ
ww72b853q40	15	21	agents	agent	NOUN
ww72b853q40	15	22	.	.	PUNCT