id	sid	tid	token	lemma	pos
xs55m903742	1	1	loss	loss	NOUN
xs55m903742	1	2	of	of	ADP
xs55m903742	1	3	heterozygosity	heterozygosity	NOUN
xs55m903742	1	4	at	at	ADP
xs55m903742	1	5	human	human	ADJ
xs55m903742	1	6	chromosome	chromosome	NOUN
xs55m903742	1	7	18q	18q	PROPN
xs55m903742	1	8	,	,	PUNCT
xs55m903742	1	9	the	the	DET
xs55m903742	1	10	region	region	NOUN
xs55m903742	1	11	containing	contain	VERB
xs55m903742	1	12	deleted	delete	VERB
xs55m903742	1	13	in	in	ADP
xs55m903742	1	14	colorectal	colorectal	ADJ
xs55m903742	1	15	cancer	cancer	NOUN
xs55m903742	1	16	(	(	PUNCT
xs55m903742	1	17	dcc	dcc	PROPN
xs55m903742	1	18	)	)	PUNCT
xs55m903742	1	19	,	,	PUNCT
xs55m903742	1	20	has	have	AUX
xs55m903742	1	21	been	be	AUX
xs55m903742	1	22	linked	link	VERB
xs55m903742	1	23	to	to	ADP
xs55m903742	1	24	a	a	DET
xs55m903742	1	25	number	number	NOUN
xs55m903742	1	26	of	of	ADP
xs55m903742	1	27	human	human	ADJ
xs55m903742	1	28	cancers	cancer	NOUN
xs55m903742	1	29	including	include	VERB
xs55m903742	1	30	colorectal	colorectal	ADJ
xs55m903742	1	31	cancer	cancer	NOUN
xs55m903742	1	32	.	.	PUNCT
xs55m903742	2	1	presently	presently	ADV
xs55m903742	2	2	no	no	DET
xs55m903742	2	3	definitive	definitive	ADJ
xs55m903742	2	4	evidence	evidence	NOUN
xs55m903742	2	5	has	have	AUX
xs55m903742	2	6	been	be	AUX
xs55m903742	2	7	detected	detect	VERB
xs55m903742	2	8	that	that	SCONJ
xs55m903742	2	9	pinpoints	pinpoint	NOUN
xs55m903742	2	10	dcc	dcc	VERB
xs55m903742	2	11	as	as	ADP
xs55m903742	2	12	being	be	AUX
xs55m903742	2	13	a	a	DET
xs55m903742	2	14	tumor	tumor	NOUN
xs55m903742	2	15	suppressor	suppressor	NOUN
xs55m903742	2	16	.	.	PUNCT
xs55m903742	3	1	here	here	ADV
xs55m903742	3	2	we	we	PRON
xs55m903742	3	3	present	present	VERB
xs55m903742	3	4	research	research	NOUN
xs55m903742	3	5	on	on	ADP
xs55m903742	3	6	frazzled	frazzle	VERB
xs55m903742	3	7	(	(	PUNCT
xs55m903742	3	8	fra	fra	X
xs55m903742	3	9	)	)	PUNCT
xs55m903742	3	10	,	,	PUNCT
xs55m903742	3	11	the	the	DET
xs55m903742	3	12	drosophila	drosophila	NOUN
xs55m903742	3	13	homolog	homolog	NOUN
xs55m903742	3	14	of	of	ADP
xs55m903742	3	15	dcc	dcc	PROPN
xs55m903742	3	16	,	,	PUNCT
xs55m903742	3	17	taking	take	VERB
xs55m903742	3	18	advantage	advantage	NOUN
xs55m903742	3	19	of	of	ADP
xs55m903742	3	20	the	the	DET
xs55m903742	3	21	powerful	powerful	ADJ
xs55m903742	3	22	genetic	genetic	ADJ
xs55m903742	3	23	tools	tool	NOUN
xs55m903742	3	24	this	this	DET
xs55m903742	3	25	model	model	NOUN
xs55m903742	3	26	organism	organism	NOUN
xs55m903742	3	27	presents	present	VERB
xs55m903742	3	28	.	.	PUNCT
xs55m903742	4	1	in	in	ADP
xs55m903742	4	2	order	order	NOUN
xs55m903742	4	3	to	to	PART
xs55m903742	4	4	determine	determine	VERB
xs55m903742	4	5	whether	whether	SCONJ
xs55m903742	4	6	fra	fra	NOUN
xs55m903742	4	7	/	/	SYM
xs55m903742	4	8	dcc	dcc	NOUN
xs55m903742	4	9	is	be	AUX
xs55m903742	4	10	a	a	DET
xs55m903742	4	11	tumor	tumor	NOUN
xs55m903742	4	12	suppressor	suppressor	NOUN
xs55m903742	4	13	we	we	PRON
xs55m903742	4	14	generated	generate	VERB
xs55m903742	4	15	fra	fra	PROPN
xs55m903742	4	16	loss	loss	NOUN
xs55m903742	4	17	of	of	ADP
xs55m903742	4	18	function	function	NOUN
xs55m903742	4	19	clones	clone	NOUN
xs55m903742	4	20	in	in	ADP
xs55m903742	4	21	drosophila	drosophila	NOUN
xs55m903742	4	22	eye	eye	NOUN
xs55m903742	4	23	discs	disc	NOUN
xs55m903742	4	24	.	.	PUNCT
xs55m903742	5	1	while	while	SCONJ
xs55m903742	5	2	these	these	DET
xs55m903742	5	3	clones	clone	NOUN
xs55m903742	5	4	had	have	VERB
xs55m903742	5	5	a	a	DET
xs55m903742	5	6	low	low	ADJ
xs55m903742	5	7	survival	survival	NOUN
xs55m903742	5	8	rate	rate	NOUN
xs55m903742	5	9	,	,	PUNCT
xs55m903742	5	10	we	we	PRON
xs55m903742	5	11	were	be	AUX
xs55m903742	5	12	able	able	ADJ
xs55m903742	5	13	to	to	PART
xs55m903742	5	14	observe	observe	VERB
xs55m903742	5	15	an	an	DET
xs55m903742	5	16	invasive	invasive	ADJ
xs55m903742	5	17	phenotype	phenotype	NOUN
xs55m903742	5	18	when	when	SCONJ
xs55m903742	5	19	we	we	PRON
xs55m903742	5	20	rescued	rescue	VERB
xs55m903742	5	21	cells	cell	NOUN
xs55m903742	5	22	from	from	ADP
xs55m903742	5	23	death	death	NOUN
xs55m903742	5	24	with	with	ADP
xs55m903742	5	25	a	a	DET
xs55m903742	5	26	secondary	secondary	ADJ
xs55m903742	5	27	genetic	genetic	ADJ
xs55m903742	5	28	modification	modification	NOUN
xs55m903742	5	29	(	(	PUNCT
xs55m903742	5	30	chapter	chapter	NOUN
xs55m903742	5	31	2	2	NUM
xs55m903742	5	32	)	)	PUNCT
xs55m903742	5	33	.	.	PUNCT
xs55m903742	6	1	from	from	ADP
xs55m903742	6	2	this	this	PRON
xs55m903742	6	3	we	we	PRON
xs55m903742	6	4	determined	determine	VERB
xs55m903742	6	5	that	that	SCONJ
xs55m903742	6	6	fra	fra	PROPN
xs55m903742	6	7	is	be	AUX
xs55m903742	6	8	a	a	DET
xs55m903742	6	9	tumor	tumor	NOUN
xs55m903742	6	10	suppressor	suppressor	NOUN
xs55m903742	6	11	and	and	CCONJ
xs55m903742	6	12	that	that	DET
xs55m903742	6	13	second	second	ADJ
xs55m903742	6	14	site	site	NOUN
xs55m903742	6	15	mutations	mutation	NOUN
xs55m903742	6	16	in	in	ADP
xs55m903742	6	17	addition	addition	NOUN
xs55m903742	6	18	to	to	ADP
xs55m903742	6	19	loss	loss	NOUN
xs55m903742	6	20	of	of	ADP
xs55m903742	6	21	fra	fra	PROPN
xs55m903742	6	22	/	/	SYM
xs55m903742	6	23	dcc	dcc	NOUN
xs55m903742	6	24	,	,	PUNCT
xs55m903742	6	25	result	result	VERB
xs55m903742	6	26	in	in	ADP
xs55m903742	6	27	highly	highly	ADV
xs55m903742	6	28	invasive	invasive	ADJ
xs55m903742	6	29	carcinomas	carcinoma	NOUN
xs55m903742	6	30	.	.	PUNCT
xs55m903742	7	1	two	two	NUM
xs55m903742	7	2	subsequent	subsequent	ADJ
xs55m903742	7	3	microarray	microarray	PROPN
xs55m903742	7	4	studies	study	NOUN
xs55m903742	7	5	were	be	AUX
xs55m903742	7	6	completed	complete	VERB
xs55m903742	7	7	to	to	PART
xs55m903742	7	8	determine	determine	VERB
xs55m903742	7	9	the	the	DET
xs55m903742	7	10	global	global	ADJ
xs55m903742	7	11	effects	effect	NOUN
xs55m903742	7	12	of	of	ADP
xs55m903742	7	13	either	either	CCONJ
xs55m903742	7	14	loss	loss	NOUN
xs55m903742	7	15	or	or	CCONJ
xs55m903742	7	16	gain	gain	NOUN
xs55m903742	7	17	of	of	ADP
xs55m903742	7	18	fra	fra	X
xs55m903742	7	19	signaling	signal	VERB
xs55m903742	7	20	.	.	PUNCT
xs55m903742	8	1	many	many	ADJ
xs55m903742	8	2	cancer	cancer	NOUN
xs55m903742	8	3	-	-	PUNCT
xs55m903742	8	4	related	relate	VERB
xs55m903742	8	5	genes	gene	NOUN
xs55m903742	8	6	were	be	AUX
xs55m903742	8	7	revealed	reveal	VERB
xs55m903742	8	8	by	by	ADP
xs55m903742	8	9	these	these	DET
xs55m903742	8	10	analyses	analysis	NOUN
xs55m903742	8	11	(	(	PUNCT
xs55m903742	8	12	chapter	chapter	NOUN
xs55m903742	8	13	3	3	NUM
xs55m903742	8	14	)	)	PUNCT
xs55m903742	8	15	.	.	PUNCT
xs55m903742	9	1	in	in	ADP
xs55m903742	9	2	order	order	NOUN
xs55m903742	9	3	to	to	PART
xs55m903742	9	4	both	both	PRON
xs55m903742	9	5	validate	validate	VERB
xs55m903742	9	6	the	the	DET
xs55m903742	9	7	microarray	microarray	PROPN
xs55m903742	9	8	results	result	NOUN
xs55m903742	9	9	and	and	CCONJ
xs55m903742	9	10	identify	identify	VERB
xs55m903742	9	11	loci	locus	NOUN
xs55m903742	9	12	that	that	PRON
xs55m903742	9	13	genetically	genetically	ADV
xs55m903742	9	14	interact	interact	VERB
xs55m903742	9	15	with	with	ADP
xs55m903742	9	16	fra	fra	NOUN
xs55m903742	9	17	,	,	PUNCT
xs55m903742	9	18	we	we	PRON
xs55m903742	9	19	proceeded	proceed	VERB
xs55m903742	9	20	with	with	ADP
xs55m903742	9	21	a	a	DET
xs55m903742	9	22	genetic	genetic	ADJ
xs55m903742	9	23	interaction	interaction	NOUN
xs55m903742	9	24	screen	screen	NOUN
xs55m903742	9	25	.	.	PUNCT
xs55m903742	10	1	results	result	NOUN
xs55m903742	10	2	of	of	ADP
xs55m903742	10	3	this	this	DET
xs55m903742	10	4	screen	screen	NOUN
xs55m903742	10	5	allowed	allow	VERB
xs55m903742	10	6	us	we	PRON
xs55m903742	10	7	to	to	PART
xs55m903742	10	8	observe	observe	VERB
xs55m903742	10	9	phenotypes	phenotype	NOUN
xs55m903742	10	10	resulting	result	VERB
xs55m903742	10	11	from	from	ADP
xs55m903742	10	12	gene	gene	NOUN
xs55m903742	10	13	mutations	mutation	NOUN
xs55m903742	10	14	in	in	ADP
xs55m903742	10	15	conjunction	conjunction	NOUN
xs55m903742	10	16	with	with	ADP
xs55m903742	10	17	loss	loss	NOUN
xs55m903742	10	18	of	of	ADP
xs55m903742	10	19	fra	fra	NOUN
xs55m903742	10	20	.	.	PUNCT
xs55m903742	11	1	many	many	ADJ
xs55m903742	11	2	interesting	interesting	ADJ
xs55m903742	11	3	genes	gene	NOUN
xs55m903742	11	4	resulted	result	VERB
xs55m903742	11	5	from	from	ADP
xs55m903742	11	6	this	this	DET
xs55m903742	11	7	screen	screen	NOUN
xs55m903742	11	8	including	include	VERB
xs55m903742	11	9	the	the	DET
xs55m903742	11	10	hedgehog	hedgehog	PROPN
xs55m903742	11	11	cascade	cascade	NOUN
xs55m903742	11	12	member	member	NOUN
xs55m903742	11	13	camp	camp	NOUN
xs55m903742	11	14	-	-	PUNCT
xs55m903742	11	15	dependent	dependent	ADJ
xs55m903742	11	16	protein	protein	NOUN
xs55m903742	11	17	kinase	kinase	NOUN
xs55m903742	11	18	1	1	NUM
xs55m903742	11	19	(	(	PUNCT
xs55m903742	11	20	pka	pka	PROPN
xs55m903742	11	21	)	)	PUNCT
xs55m903742	11	22	(	(	PUNCT
xs55m903742	11	23	chapter	chapter	NOUN
xs55m903742	11	24	4	4	NUM
xs55m903742	11	25	)	)	PUNCT
xs55m903742	11	26	.	.	PUNCT
xs55m903742	12	1	assays	assay	NOUN
xs55m903742	12	2	were	be	AUX
xs55m903742	12	3	then	then	ADV
xs55m903742	12	4	designed	design	VERB
xs55m903742	12	5	to	to	PART
xs55m903742	12	6	study	study	VERB
xs55m903742	12	7	the	the	DET
xs55m903742	12	8	effects	effect	NOUN
xs55m903742	12	9	of	of	ADP
xs55m903742	12	10	loss	loss	NOUN
xs55m903742	12	11	of	of	ADP
xs55m903742	12	12	both	both	DET
xs55m903742	12	13	fra	fra	NOUN
xs55m903742	12	14	and	and	CCONJ
xs55m903742	12	15	pka	pka	PROPN
xs55m903742	12	16	.	.	PUNCT
xs55m903742	13	1	from	from	ADP
xs55m903742	13	2	these	these	DET
xs55m903742	13	3	analyses	analysis	NOUN
xs55m903742	13	4	we	we	PRON
xs55m903742	13	5	were	be	AUX
xs55m903742	13	6	able	able	ADJ
xs55m903742	13	7	to	to	PART
xs55m903742	13	8	determine	determine	VERB
xs55m903742	13	9	that	that	DET
xs55m903742	13	10	loss	loss	NOUN
xs55m903742	13	11	of	of	ADP
xs55m903742	13	12	both	both	PRON
xs55m903742	13	13	of	of	ADP
xs55m903742	13	14	these	these	DET
xs55m903742	13	15	genes	gene	NOUN
xs55m903742	13	16	results	result	VERB
xs55m903742	13	17	in	in	ADP
xs55m903742	13	18	cells	cell	NOUN
xs55m903742	13	19	that	that	PRON
xs55m903742	13	20	are	be	AUX
xs55m903742	13	21	highly	highly	ADV
xs55m903742	13	22	invasive	invasive	ADJ
xs55m903742	13	23	(	(	PUNCT
xs55m903742	13	24	chapter	chapter	NOUN
xs55m903742	13	25	5	5	NUM
xs55m903742	13	26	)	)	PUNCT
xs55m903742	13	27	.	.	PUNCT
xs55m903742	14	1	the	the	DET
xs55m903742	14	2	work	work	NOUN
xs55m903742	14	3	presented	present	VERB
xs55m903742	14	4	in	in	ADP
xs55m903742	14	5	this	this	DET
xs55m903742	14	6	study	study	NOUN
xs55m903742	14	7	is	be	AUX
xs55m903742	14	8	the	the	DET
xs55m903742	14	9	first	first	ADJ
xs55m903742	14	10	direct	direct	ADJ
xs55m903742	14	11	evidence	evidence	NOUN
xs55m903742	14	12	,	,	PUNCT
xs55m903742	14	13	in	in	ADP
xs55m903742	14	14	any	any	DET
xs55m903742	14	15	animal	animal	NOUN
xs55m903742	14	16	model	model	NOUN
xs55m903742	14	17	,	,	PUNCT
xs55m903742	14	18	that	that	PRON
xs55m903742	14	19	fra	fra	VERB
xs55m903742	14	20	/	/	SYM
xs55m903742	14	21	dcc	dcc	NOUN
xs55m903742	14	22	is	be	AUX
xs55m903742	14	23	a	a	DET
xs55m903742	14	24	tumor	tumor	NOUN
xs55m903742	14	25	suppressor	suppressor	NOUN
xs55m903742	14	26	.	.	PUNCT
xs55m903742	15	1	it	it	PRON
xs55m903742	15	2	has	have	AUX
xs55m903742	15	3	also	also	ADV
xs55m903742	15	4	identified	identify	VERB
xs55m903742	15	5	a	a	DET
xs55m903742	15	6	number	number	NOUN
xs55m903742	15	7	of	of	ADP
xs55m903742	15	8	genes	gene	NOUN
xs55m903742	15	9	that	that	PRON
xs55m903742	15	10	when	when	SCONJ
xs55m903742	15	11	mutated	mutate	VERB
xs55m903742	15	12	in	in	ADP
xs55m903742	15	13	conjunction	conjunction	NOUN
xs55m903742	15	14	with	with	ADP
xs55m903742	15	15	loss	loss	NOUN
xs55m903742	15	16	of	of	ADP
xs55m903742	15	17	fra	fra	NOUN
xs55m903742	15	18	/	/	SYM
xs55m903742	15	19	dcc	dcc	NOUN
xs55m903742	15	20	result	result	NOUN
xs55m903742	15	21	in	in	ADP
xs55m903742	15	22	increased	increase	VERB
xs55m903742	15	23	invasion	invasion	NOUN
xs55m903742	15	24	.	.	PUNCT
xs55m903742	16	1	the	the	DET
xs55m903742	16	2	results	result	NOUN
xs55m903742	16	3	of	of	ADP
xs55m903742	16	4	this	this	DET
xs55m903742	16	5	investigation	investigation	NOUN
xs55m903742	16	6	provide	provide	VERB
xs55m903742	16	7	new	new	ADJ
xs55m903742	16	8	insight	insight	NOUN
xs55m903742	16	9	into	into	ADP
xs55m903742	16	10	the	the	DET
xs55m903742	16	11	mechanisms	mechanism	NOUN
xs55m903742	16	12	involved	involve	VERB
xs55m903742	16	13	in	in	ADP
xs55m903742	16	14	tumorigenesis	tumorigenesis	NOUN
xs55m903742	16	15	and	and	CCONJ
xs55m903742	16	16	metastasis	metastasis	NOUN
xs55m903742	16	17	resulting	result	VERB
xs55m903742	16	18	from	from	ADP
xs55m903742	16	19	loss	loss	NOUN
xs55m903742	16	20	of	of	ADP
xs55m903742	16	21	dcc	dcc	PROPN
xs55m903742	16	22	.	.	PUNCT