id sid tid token lemma pos news-003825 1 1 paper paper NOUN news-003825 1 2 sheds shed VERB news-003825 1 3 new new ADJ news-003825 1 4 " " PUNCT news-003825 1 5 light light ADJ news-003825 1 6 " " PUNCT news-003825 1 7 on on ADP news-003825 1 8 fascinating fascinating ADJ news-003825 1 9 rhythms rhythm NOUN news-003825 1 10 of of ADP news-003825 1 11 the the DET news-003825 1 12 circadian circadian ADJ news-003825 1 13 clock clock NOUN news-003825 1 14 | | NOUN news-003825 1 15 news news PROPN news-003825 1 16 | | PROPN news-003825 1 17 notre notre PROPN news-003825 1 18 dame dame PROPN news-003825 1 19 news news PROPN news-003825 1 20 | | PROPN news-003825 1 21 university university PROPN news-003825 1 22 of of ADP news-003825 1 23 notre notre PROPN news-003825 1 24 dame dame PROPN news-003825 1 25 skip skip VERB news-003825 1 26 to to ADP news-003825 1 27 content content NOUN news-003825 1 28 skip skip VERB news-003825 1 29 to to ADP news-003825 1 30 navigation navigation NOUN news-003825 1 31 skip skip VERB news-003825 1 32 to to PART news-003825 1 33 search search VERB news-003825 1 34 university university PROPN news-003825 1 35 of of ADP news-003825 1 36 notre notre PROPN news-003825 1 37 dame dame PROPN news-003825 1 38 notre notre PROPN news-003825 1 39 dame dame PROPN news-003825 1 40 news news PROPN news-003825 1 41 experts expert NOUN news-003825 1 42 nd nd PROPN news-003825 1 43 in in ADP news-003825 1 44 the the DET news-003825 1 45 news news NOUN news-003825 1 46 subscribe subscribe NOUN news-003825 1 47 about about ADP news-003825 1 48 us us PROPN news-003825 1 49 home home NOUN news-003825 1 50 contact contact NOUN news-003825 1 51 search search NOUN news-003825 1 52 menu menu NOUN news-003825 1 53 home home ADV news-003825 1 54 › › ADP news-003825 1 55 news news NOUN news-003825 1 56 › › ADP news-003825 1 57 paper paper NOUN news-003825 1 58 sheds shed VERB news-003825 1 59 new new ADJ news-003825 1 60 " " PUNCT news-003825 1 61 light light ADJ news-003825 1 62 " " PUNCT news-003825 1 63 on on ADP news-003825 1 64 fascinating fascinating ADJ news-003825 1 65 rhythms rhythm NOUN news-003825 1 66 of of ADP news-003825 1 67 the the DET news-003825 1 68 circadian circadian ADJ news-003825 1 69 clock clock NOUN news-003825 1 70 paper paper NOUN news-003825 1 71 sheds shed VERB news-003825 1 72 new new ADJ news-003825 1 73 " " PUNCT news-003825 1 74 light light ADJ news-003825 1 75 " " PUNCT news-003825 1 76 on on ADP news-003825 1 77 fascinating fascinating ADJ news-003825 1 78 rhythms rhythm NOUN news-003825 1 79 of of ADP news-003825 1 80 the the DET news-003825 1 81 circadian circadian ADJ news-003825 1 82 clock clock NOUN news-003825 1 83 published publish VERB news-003825 1 84 : : PUNCT news-003825 1 85 february february PROPN news-003825 1 86 15 15 NUM news-003825 1 87 , , PUNCT news-003825 1 88 2009 2009 NUM news-003825 1 89 author author NOUN news-003825 1 90 : : PUNCT news-003825 1 91 william william PROPN news-003825 1 92 g. g. PROPN news-003825 1 93 gilroy gilroy PROPN news-003825 1 94 scientists scientist NOUN news-003825 1 95 have have AUX news-003825 1 96 long long ADV news-003825 1 97 known know VERB news-003825 1 98 that that SCONJ news-003825 1 99 interrupting interrupt VERB news-003825 1 100 the the DET news-003825 1 101 24 24 NUM news-003825 1 102 - - PUNCT news-003825 1 103 hour hour NOUN news-003825 1 104 circadian circadian ADJ news-003825 1 105 rhythm rhythm NOUN news-003825 1 106 plays play VERB news-003825 1 107 havoc havoc NOUN news-003825 1 108 with with ADP news-003825 1 109 the the DET news-003825 1 110 lives life NOUN news-003825 1 111 and and CCONJ news-003825 1 112 health health NOUN news-003825 1 113 of of ADP news-003825 1 114 medical medical ADJ news-003825 1 115 , , PUNCT news-003825 1 116 military military NOUN news-003825 1 117 and and CCONJ news-003825 1 118 airline airline NOUN news-003825 1 119 personnel personnel NOUN news-003825 1 120 , , PUNCT news-003825 1 121 factory factory NOUN news-003825 1 122 employees employee NOUN news-003825 1 123 and and CCONJ news-003825 1 124 travelers traveler NOUN news-003825 1 125 . . PUNCT news-003825 2 1 a a DET news-003825 2 2 new new ADJ news-003825 2 3 paper paper NOUN news-003825 2 4 by by ADP news-003825 2 5 university university PROPN news-003825 2 6 of of ADP news-003825 2 7 notre notre PROPN news-003825 2 8 dame dame NOUN news-003825 2 9 biologist biologist NOUN news-003825 2 10 giles gile NOUN news-003825 2 11 duffield duffield PROPN news-003825 2 12 and and CCONJ news-003825 2 13 a a DET news-003825 2 14 team team NOUN news-003825 2 15 of of ADP news-003825 2 16 researchers researcher NOUN news-003825 2 17 that that PRON news-003825 2 18 appears appear VERB news-003825 2 19 in in ADP news-003825 2 20 this this DET news-003825 2 21 month month NOUN news-003825 2 22 ’s ’s PART news-003825 2 23 edition edition NOUN news-003825 2 24 of of ADP news-003825 2 25 the the DET news-003825 2 26 journal journal NOUN news-003825 2 27 current current ADJ news-003825 2 28 biology biology NOUN news-003825 2 29 sheds shed VERB news-003825 2 30 new new ADJ news-003825 2 31 light light NOUN news-003825 2 32 on on ADP news-003825 2 33 circadian circadian ADJ news-003825 2 34 timing timing NOUN news-003825 2 35 systems system NOUN news-003825 2 36 and and CCONJ news-003825 2 37 focuses focus VERB news-003825 2 38 on on ADP news-003825 2 39 a a DET news-003825 2 40 key key ADJ news-003825 2 41 gene gene NOUN news-003825 2 42 that that PRON news-003825 2 43 seems seem VERB news-003825 2 44 to to PART news-003825 2 45 regulate regulate VERB news-003825 2 46 the the DET news-003825 2 47 response response NOUN news-003825 2 48 of of ADP news-003825 2 49 the the DET news-003825 2 50 circadian circadian ADJ news-003825 2 51 clock clock NOUN news-003825 2 52 to to ADP news-003825 2 53 light light ADJ news-003825 2 54 signals signal NOUN news-003825 2 55 . . PUNCT news-003825 3 1 “ " PUNCT news-003825 3 2 circadian circadian ADJ news-003825 3 3 rhythms rhythm NOUN news-003825 3 4 are be AUX news-003825 3 5 important important ADJ news-003825 3 6 and and CCONJ news-003825 3 7 exciting exciting ADJ news-003825 3 8 because because SCONJ news-003825 3 9 they they PRON news-003825 3 10 pervade pervade VERB news-003825 3 11 many many ADJ news-003825 3 12 aspects aspect NOUN news-003825 3 13 of of ADP news-003825 3 14 biochemistry biochemistry NOUN news-003825 3 15 , , PUNCT news-003825 3 16 physiology physiology NOUN news-003825 3 17 and and CCONJ news-003825 3 18 behavior behavior NOUN news-003825 3 19 , , PUNCT news-003825 3 20 either either CCONJ news-003825 3 21 subtly subtly ADV news-003825 3 22 or or CCONJ news-003825 3 23 overtly,”duffield overtly,”duffield X news-003825 3 24 said say VERB news-003825 3 25 . . PUNCT news-003825 4 1 “for “for PUNCT news-003825 4 2 example example NOUN news-003825 4 3 , , PUNCT news-003825 4 4 the the DET news-003825 4 5 human human ADJ news-003825 4 6 sleep sleep NOUN news-003825 4 7 - - PUNCT news-003825 4 8 wake wake NOUN news-003825 4 9 cycle cycle NOUN news-003825 4 10 is be AUX news-003825 4 11 a a DET news-003825 4 12 very very ADV news-003825 4 13 obvious obvious ADJ news-003825 4 14 rhythm rhythm NOUN news-003825 4 15 and and CCONJ news-003825 4 16 tightly tightly ADV news-003825 4 17 gated gate VERB news-003825 4 18 to to ADP news-003825 4 19 the the DET news-003825 4 20 night night NOUN news-003825 4 21 , , PUNCT news-003825 4 22 while while SCONJ news-003825 4 23 perhaps perhaps ADV news-003825 4 24 less less ADV news-003825 4 25 obvious obvious ADJ news-003825 4 26 is be AUX news-003825 4 27 that that SCONJ news-003825 4 28 virtually virtually ADV news-003825 4 29 all all DET news-003825 4 30 hormones hormone NOUN news-003825 4 31 oscillate oscillate VERB news-003825 4 32 with with ADP news-003825 4 33 a a DET news-003825 4 34 24 24 NUM news-003825 4 35 - - PUNCT news-003825 4 36 hour hour NOUN news-003825 4 37 rhythm rhythm NOUN news-003825 4 38 and and CCONJ news-003825 4 39 up up ADP news-003825 4 40 to to PART news-003825 4 41 10 10 NUM news-003825 4 42 percent percent NOUN news-003825 4 43 of of ADP news-003825 4 44 genes gene NOUN news-003825 4 45 in in ADP news-003825 4 46 each each DET news-003825 4 47 cell cell NOUN news-003825 4 48 are be AUX news-003825 4 49 rhythmically rhythmically ADV news-003825 4 50 controlled control VERB news-003825 4 51 . . PUNCT news-003825 4 52 ” " PUNCT news-003825 5 1 an an DET news-003825 5 2 estimated estimate VERB news-003825 5 3 16 16 NUM news-003825 5 4 percent percent NOUN news-003825 5 5 of of ADP news-003825 5 6 the the DET news-003825 5 7 u.s u.s PROPN news-003825 5 8 . . PROPN news-003825 5 9 working working PROPN news-003825 5 10 population population NOUN news-003825 5 11 is be AUX news-003825 5 12 involved involve VERB news-003825 5 13 in in ADP news-003825 5 14 rotational rotational ADJ news-003825 5 15 shift shift NOUN news-003825 5 16 work work NOUN news-003825 5 17 , , PUNCT news-003825 5 18 and and CCONJ news-003825 5 19 a a DET news-003825 5 20 significant significant ADJ news-003825 5 21 population population NOUN news-003825 5 22 is be AUX news-003825 5 23 affected affect VERB news-003825 5 24 by by ADP news-003825 5 25 jet jet NOUN news-003825 5 26 lag lag NOUN news-003825 5 27 and and CCONJ news-003825 5 28 related relate VERB news-003825 5 29 sleep sleep NOUN news-003825 5 30 - - PUNCT news-003825 5 31 wake wake NOUN news-003825 5 32 disorders disorder NOUN news-003825 5 33 . . PUNCT news-003825 6 1 the the DET news-003825 6 2 impact impact NOUN news-003825 6 3 of of ADP news-003825 6 4 the the DET news-003825 6 5 large large ADJ news-003825 6 6 shifts shift NOUN news-003825 6 7 in in ADP news-003825 6 8 the the DET news-003825 6 9 body body NOUN news-003825 6 10 ’s ’s PART news-003825 6 11 internal internal ADJ news-003825 6 12 clock clock NOUN news-003825 6 13 that that PRON news-003825 6 14 these these DET news-003825 6 15 individuals individual NOUN news-003825 6 16 experience experience VERB news-003825 6 17 can can AUX news-003825 6 18 be be AUX news-003825 6 19 profound profound ADJ news-003825 6 20 , , PUNCT news-003825 6 21 contributing contribute VERB news-003825 6 22 to to ADP news-003825 6 23 increased increase VERB news-003825 6 24 accident accident NOUN news-003825 6 25 rates rate NOUN news-003825 6 26 , , PUNCT news-003825 6 27 medical medical ADJ news-003825 6 28 errors error NOUN news-003825 6 29 and and CCONJ news-003825 6 30 the the DET news-003825 6 31 development development NOUN news-003825 6 32 of of ADP news-003825 6 33 particular particular ADJ news-003825 6 34 illnesses illness NOUN news-003825 6 35 . . PUNCT news-003825 7 1 “ " PUNCT news-003825 7 2 both both CCONJ news-003825 7 3 the the DET news-003825 7 4 three three NUM news-003825 7 5 mile mile NOUN news-003825 7 6 island island NOUN news-003825 7 7 disaster disaster NOUN news-003825 7 8 in in ADP news-003825 7 9 1979 1979 NUM news-003825 7 10 and and CCONJ news-003825 7 11 the the DET news-003825 7 12 chernobyl chernobyl NOUN news-003825 7 13 disaster disaster NOUN news-003825 7 14 in in ADP news-003825 7 15 1986 1986 NUM news-003825 7 16 occurred occur VERB news-003825 7 17 late late ADV news-003825 7 18 at at ADP news-003825 7 19 night night NOUN news-003825 7 20 or or CCONJ news-003825 7 21 early early ADV news-003825 7 22 in in ADP news-003825 7 23 the the DET news-003825 7 24 morning,”duffield morning,”duffield NOUN news-003825 7 25 said say VERB news-003825 7 26 . . PUNCT news-003825 8 1 “most “most NOUN news-003825 8 2 truck truck NOUN news-003825 8 3 accidents accident NOUN news-003825 8 4 occur occur VERB news-003825 8 5 around around ADV news-003825 8 6 2 2 NUM news-003825 8 7 a.m. a.m. NOUN news-003825 8 8 incidents incident NOUN news-003825 8 9 of of ADP news-003825 8 10 cancer cancer NOUN news-003825 8 11 and and CCONJ news-003825 8 12 cardiovascular cardiovascular ADJ news-003825 8 13 disease disease NOUN news-003825 8 14 are be AUX news-003825 8 15 elevated elevate VERB news-003825 8 16 in in ADP news-003825 8 17 trans trans ADJ news-003825 8 18 - - ADJ news-003825 8 19 atlantic atlantic ADJ news-003825 8 20 airline airline NOUN news-003825 8 21 staff staff NOUN news-003825 8 22 and and CCONJ news-003825 8 23 in in ADP news-003825 8 24 shift shift NOUN news-003825 8 25 workers worker NOUN news-003825 8 26 . . PUNCT news-003825 8 27 ” " PUNCT news-003825 9 1 the the DET news-003825 9 2 master master NOUN news-003825 9 3 circadian circadian ADJ news-003825 9 4 clock clock NOUN news-003825 9 5 in in ADP news-003825 9 6 the the DET news-003825 9 7 human human NOUN news-003825 9 8 resides reside VERB news-003825 9 9 within within ADP news-003825 9 10 the the DET news-003825 9 11 suprachiasmatic suprachiasmatic ADJ news-003825 9 12 nucleus nucleus NOUN news-003825 9 13 of of ADP news-003825 9 14 the the DET news-003825 9 15 hypothalamic hypothalamic ADJ news-003825 9 16 brain brain NOUN news-003825 9 17 and and CCONJ news-003825 9 18 receives receive VERB news-003825 9 19 direct direct ADJ news-003825 9 20 input input NOUN news-003825 9 21 from from ADP news-003825 9 22 the the DET news-003825 9 23 retina retina NOUN news-003825 9 24 ( ( PUNCT news-003825 9 25 eye eye NOUN news-003825 9 26 ) ) PUNCT news-003825 9 27 through through ADP news-003825 9 28 which which PRON news-003825 9 29 the the DET news-003825 9 30 clock clock NOUN news-003825 9 31 can can AUX news-003825 9 32 be be AUX news-003825 9 33 reset reset VERB news-003825 9 34 or or CCONJ news-003825 9 35 synchronized synchronize VERB news-003825 9 36 on on ADP news-003825 9 37 a a DET news-003825 9 38 daily daily ADJ news-003825 9 39 basis basis NOUN news-003825 9 40 to to ADP news-003825 9 41 the the DET news-003825 9 42 prevailing prevail VERB news-003825 9 43 light light ADJ news-003825 9 44 - - PUNCT news-003825 9 45 dark dark NOUN news-003825 9 46 cycle cycle NOUN news-003825 9 47 . . PUNCT news-003825 10 1 this this PRON news-003825 10 2 provides provide VERB news-003825 10 3 both both DET news-003825 10 4 time time NOUN news-003825 10 5 of of ADP news-003825 10 6 day day NOUN news-003825 10 7 and and CCONJ news-003825 10 8 also also ADV news-003825 10 9 time time NOUN news-003825 10 10 of of ADP news-003825 10 11 year year NOUN news-003825 10 12 information information NOUN news-003825 10 13 to to ADP news-003825 10 14 the the DET news-003825 10 15 brain brain NOUN news-003825 10 16 and and CCONJ news-003825 10 17 body body NOUN news-003825 10 18 . . PUNCT news-003825 11 1 things thing NOUN news-003825 11 2 can can AUX news-003825 11 3 go go VERB news-003825 11 4 wrong wrong ADJ news-003825 11 5 with with ADP news-003825 11 6 the the DET news-003825 11 7 internal internal ADJ news-003825 11 8 clocks clock NOUN news-003825 11 9 when when SCONJ news-003825 11 10 either either CCONJ news-003825 11 11 the the DET news-003825 11 12 clock clock NOUN news-003825 11 13 system system NOUN news-003825 11 14 or or CCONJ news-003825 11 15 its its PRON news-003825 11 16 light light ADJ news-003825 11 17 input input NOUN news-003825 11 18 pathway pathway NOUN news-003825 11 19 is be AUX news-003825 11 20 disrupted disrupt VERB news-003825 11 21 . . PUNCT news-003825 12 1 using use VERB news-003825 12 2 dna dna PROPN news-003825 12 3 microarray microarray PROPN news-003825 12 4 techniques techniques PROPN news-003825 12 5 , , PUNCT news-003825 12 6 duffield duffield PROPN news-003825 12 7 and and CCONJ news-003825 12 8 the the DET news-003825 12 9 other other ADJ news-003825 12 10 researchers researcher NOUN news-003825 12 11 identified identify VERB news-003825 12 12 an an DET news-003825 12 13 important important ADJ news-003825 12 14 gene gene NOUN news-003825 12 15 called call VERB news-003825 12 16 the"inhibitor the"inhibitor PROPN news-003825 12 17 of of ADP news-003825 12 18 dna dna PROPN news-003825 12 19 - - PUNCT news-003825 12 20 binding bind VERB news-003825 12 21 2"(id2 2"(id2 NUM news-003825 12 22 ) ) PUNCT news-003825 12 23 and and CCONJ news-003825 12 24 found find VERB news-003825 12 25 that that SCONJ news-003825 12 26 the the DET news-003825 12 27 gene gene NOUN news-003825 12 28 is be AUX news-003825 12 29 rhythmically rhythmically ADV news-003825 12 30 expressed express VERB news-003825 12 31 in in ADP news-003825 12 32 various various ADJ news-003825 12 33 tissues tissue NOUN news-003825 12 34 including include VERB news-003825 12 35 the the DET news-003825 12 36 suprachiasmatic suprachiasmatic ADJ news-003825 12 37 nucleus nucleus NOUN news-003825 12 38 . . PUNCT news-003825 13 1 “ " PUNCT news-003825 13 2 in in ADP news-003825 13 3 the the DET news-003825 13 4 last last ADJ news-003825 13 5 few few ADJ news-003825 13 6 years year NOUN news-003825 13 7 , , PUNCT news-003825 13 8 my my PRON news-003825 13 9 laboratory laboratory NOUN news-003825 13 10 has have AUX news-003825 13 11 focused focus VERB news-003825 13 12 on on ADP news-003825 13 13 a a DET news-003825 13 14 family family NOUN news-003825 13 15 of of ADP news-003825 13 16 transcription transcription NOUN news-003825 13 17 factor factor NOUN news-003825 13 18 genes gene NOUN news-003825 13 19 expressed express VERB news-003825 13 20 in in ADP news-003825 13 21 the the DET news-003825 13 22 suprachiasmatic suprachiasmatic ADJ news-003825 13 23 nucleus nucleus NOUN news-003825 13 24 , , PUNCT news-003825 13 25 liver liver NOUN news-003825 13 26 and and CCONJ news-003825 13 27 heart,”duffield heart,”duffield VERB news-003825 13 28 said say VERB news-003825 13 29 . . PUNCT news-003825 14 1 "in "in NUM news-003825 15 1 conjunction conjunction NOUN news-003825 15 2 with with ADP news-003825 15 3 colleagues colleague NOUN news-003825 15 4 at at ADP news-003825 15 5 dartmouth dartmouth NOUN news-003825 15 6 medical medical ADJ news-003825 15 7 school school NOUN news-003825 15 8 and and CCONJ news-003825 15 9 norris norris PROPN news-003825 15 10 cotton cotton NOUN news-003825 15 11 cancer cancer NOUN news-003825 15 12 center center NOUN news-003825 15 13 , , PUNCT news-003825 15 14 we we PRON news-003825 15 15 produced produce VERB news-003825 15 16 a a DET news-003825 15 17 knockout knockout NOUN news-003825 15 18 mouse mouse NOUN news-003825 15 19 that that PRON news-003825 15 20 does do AUX news-003825 15 21 not not PART news-003825 15 22 express express VERB news-003825 15 23 the the DET news-003825 15 24 id2 id2 NOUN news-003825 15 25 gene gene NOUN news-003825 15 26 and and CCONJ news-003825 15 27 is be AUX news-003825 15 28 thus thus ADV news-003825 15 29 null null ADJ news-003825 15 30 for for ADP news-003825 15 31 the the DET news-003825 15 32 functional functional ADJ news-003825 15 33 id2 id2 PROPN news-003825 15 34 protein protein NOUN news-003825 15 35 . . PUNCT news-003825 16 1 by by ADP news-003825 16 2 exposing expose VERB news-003825 16 3 these these DET news-003825 16 4 mice mouse NOUN news-003825 16 5 to to ADP news-003825 16 6 a a DET news-003825 16 7 time time NOUN news-003825 16 8 - - PUNCT news-003825 16 9 zone zone NOUN news-003825 16 10 change change NOUN news-003825 16 11 in in ADP news-003825 16 12 their their PRON news-003825 16 13 light light ADJ news-003825 16 14 - - PUNCT news-003825 16 15 dark dark NOUN news-003825 16 16 cycle cycle NOUN news-003825 16 17 , , PUNCT news-003825 16 18 we we PRON news-003825 16 19 were be AUX news-003825 16 20 able able ADJ news-003825 16 21 to to PART news-003825 16 22 examine examine VERB news-003825 16 23 the the DET news-003825 16 24 effect effect NOUN news-003825 16 25 of of ADP news-003825 16 26 artificial artificial ADJ news-003825 16 27 jet jet NOUN news-003825 16 28 lag lag NOUN news-003825 16 29 . . PUNCT news-003825 17 1 we we PRON news-003825 17 2 altered alter VERB news-003825 17 3 the the DET news-003825 17 4 light light ADJ news-003825 17 5 - - PUNCT news-003825 17 6 dark dark ADJ news-003825 17 7 conditions condition NOUN news-003825 17 8 for for ADP news-003825 17 9 these these DET news-003825 17 10 mice mouse NOUN news-003825 17 11 to to PART news-003825 17 12 produce produce VERB news-003825 17 13 an an DET news-003825 17 14 effect effect NOUN news-003825 17 15 that that PRON news-003825 17 16 was be AUX news-003825 17 17 the the DET news-003825 17 18 equivalent equivalent NOUN news-003825 17 19 of of ADP news-003825 17 20 a a DET news-003825 17 21 person person NOUN news-003825 17 22 flying fly VERB news-003825 17 23 from from ADP news-003825 17 24 athens athens PROPN news-003825 17 25 to to ADP news-003825 17 26 los los PROPN news-003825 17 27 angeles angeles PROPN news-003825 17 28 , , PUNCT news-003825 17 29 a a DET news-003825 17 30 10 10 NUM news-003825 17 31 - - PUNCT news-003825 17 32 hour hour NOUN news-003825 17 33 delay delay NOUN news-003825 17 34 of of ADP news-003825 17 35 their their PRON news-003825 17 36 cycle cycle NOUN news-003825 17 37 . . PUNCT news-003825 18 1 “ " PUNCT news-003825 18 2 we we PRON news-003825 18 3 discovered discover VERB news-003825 18 4 that that SCONJ news-003825 18 5 the the DET news-003825 18 6 knockout knockout NOUN news-003825 18 7 mice mouse NOUN news-003825 18 8 took take VERB news-003825 18 9 only only ADV news-003825 18 10 one one NUM news-003825 18 11 or or CCONJ news-003825 18 12 two two NUM news-003825 18 13 days day NOUN news-003825 18 14 to to PART news-003825 18 15 recover recover VERB news-003825 18 16 from from ADP news-003825 18 17 jet jet NOUN news-003825 18 18 lag lag PROPN news-003825 18 19 , , PUNCT news-003825 18 20 while while SCONJ news-003825 18 21 unaltered unaltered ADJ news-003825 18 22 mice mouse NOUN news-003825 18 23 required require VERB news-003825 18 24 four four NUM news-003825 18 25 or or CCONJ news-003825 18 26 five five NUM news-003825 18 27 days day NOUN news-003825 18 28 to to PART news-003825 18 29 fully fully ADV news-003825 18 30 adjust adjust VERB news-003825 18 31 . . PUNCT news-003825 19 1 it it PRON news-003825 19 2 ’s ’ VERB news-003825 19 3 like like SCONJ news-003825 19 4 we we PRON news-003825 19 5 removed remove VERB news-003825 19 6 the the DET news-003825 19 7 hand hand NOUN news-003825 19 8 brake brake NOUN news-003825 19 9 on on ADP news-003825 19 10 their their PRON news-003825 19 11 molecular molecular ADJ news-003825 19 12 machinery machinery NOUN news-003825 19 13 . . PUNCT news-003825 19 14 ” " PUNCT news-003825 20 1 the the DET news-003825 20 2 experimental experimental ADJ news-003825 20 3 results result NOUN news-003825 20 4 have have VERB news-003825 20 5 important important ADJ news-003825 20 6 implications implication NOUN news-003825 20 7 for for ADP news-003825 20 8 understanding understand VERB news-003825 20 9 the the DET news-003825 20 10 development development NOUN news-003825 20 11 and and CCONJ news-003825 20 12 functioning functioning NOUN news-003825 20 13 of of ADP news-003825 20 14 the the DET news-003825 20 15 circadian circadian ADJ news-003825 20 16 clock clock NOUN news-003825 20 17 in in ADP news-003825 20 18 the the DET news-003825 20 19 brain brain NOUN news-003825 20 20 and and CCONJ news-003825 20 21 peripheral peripheral ADJ news-003825 20 22 tissues tissue NOUN news-003825 20 23 such such ADJ news-003825 20 24 as as ADP news-003825 20 25 the the DET news-003825 20 26 liver liver NOUN news-003825 20 27 and and CCONJ news-003825 20 28 heart heart NOUN news-003825 20 29 . . PUNCT news-003825 21 1 “ " PUNCT news-003825 21 2 eight eight NUM news-003825 21 3 years year NOUN news-003825 21 4 ago ago ADV news-003825 21 5 , , PUNCT news-003825 21 6 researchers researcher NOUN news-003825 21 7 realized realize VERB news-003825 21 8 that that SCONJ news-003825 21 9 even even ADV news-003825 21 10 if if SCONJ news-003825 21 11 you you PRON news-003825 21 12 destroy destroy VERB news-003825 21 13 the the DET news-003825 21 14 suprachiasmatic suprachiasmatic ADJ news-003825 21 15 nuclei nucleus NOUN news-003825 21 16 of of ADP news-003825 21 17 the the DET news-003825 21 18 hypothalamus hypothalamus PROPN news-003825 21 19 or or CCONJ news-003825 21 20 examine examine VERB news-003825 21 21 peripheral peripheral ADJ news-003825 21 22 organs organ NOUN news-003825 21 23 in in ADP news-003825 21 24 isolation isolation NOUN news-003825 21 25 , , PUNCT news-003825 21 26 there there PRON news-003825 21 27 are be VERB news-003825 21 28 still still ADV news-003825 21 29 working work VERB news-003825 21 30 clock clock NOUN news-003825 21 31 systems system NOUN news-003825 21 32 in in ADP news-003825 21 33 many many ADJ news-003825 21 34 other other ADJ news-003825 21 35 tissues tissue NOUN news-003825 21 36 of of ADP news-003825 21 37 the the DET news-003825 21 38 body,”duffield body,”duffield NOUN news-003825 21 39 said say VERB news-003825 21 40 . . PUNCT news-003825 22 1 it it PRON news-003825 22 2 turns turn VERB news-003825 22 3 out out ADP news-003825 22 4 that that SCONJ news-003825 22 5 many many ADJ news-003825 22 6 of of ADP news-003825 22 7 the the DET news-003825 22 8 cells cell NOUN news-003825 22 9 throughout throughout ADP news-003825 22 10 our our PRON news-003825 22 11 bodies body NOUN news-003825 22 12 have have VERB news-003825 22 13 an an DET news-003825 22 14 intrinsic intrinsic ADJ news-003825 22 15 circadian circadian ADJ news-003825 22 16 clock clock NOUN news-003825 22 17 mechanism mechanism NOUN news-003825 22 18 and and CCONJ news-003825 22 19 that that SCONJ news-003825 22 20 jet jet NOUN news-003825 22 21 lag lag NOUN news-003825 22 22 and and CCONJ news-003825 22 23 shift shift NOUN news-003825 22 24 work work NOUN news-003825 22 25 can can AUX news-003825 22 26 produce produce VERB news-003825 22 27 internal internal ADJ news-003825 22 28 asynchrony asynchrony NOUN news-003825 22 29 between between ADP news-003825 22 30 each each PRON news-003825 22 31 of of ADP news-003825 22 32 our our PRON news-003825 22 33 tissue tissue NOUN news-003825 22 34 - - PUNCT news-003825 22 35 specific specific ADJ news-003825 22 36 clocks clock NOUN news-003825 22 37 . . PUNCT news-003825 23 1 our our PRON news-003825 23 2 brains brain NOUN news-003825 23 3 , , PUNCT news-003825 23 4 on on ADP news-003825 23 5 a a DET news-003825 23 6 daily daily ADJ news-003825 23 7 basis basis NOUN news-003825 23 8 , , PUNCT news-003825 23 9 generate generate VERB news-003825 23 10 the the DET news-003825 23 11 hormonal hormonal ADJ news-003825 23 12 and and CCONJ news-003825 23 13 neuronal neuronal ADJ news-003825 23 14 signals signal NOUN news-003825 23 15 that that PRON news-003825 23 16 influence influence VERB news-003825 23 17 the the DET news-003825 23 18 cellular cellular ADJ news-003825 23 19 clocks clock NOUN news-003825 23 20 in in ADP news-003825 23 21 the the DET news-003825 23 22 peripheral peripheral ADJ news-003825 23 23 tissues tissue NOUN news-003825 23 24 . . PUNCT news-003825 24 1 if if SCONJ news-003825 24 2 this this DET news-003825 24 3 communication communication NOUN news-003825 24 4 line line NOUN news-003825 24 5 is be AUX news-003825 24 6 disrupted disrupt VERB news-003825 24 7 , , PUNCT news-003825 24 8 the the DET news-003825 24 9 liver liver NOUN news-003825 24 10 , , PUNCT news-003825 24 11 for for ADP news-003825 24 12 example example NOUN news-003825 24 13 , , PUNCT news-003825 24 14 ends end VERB news-003825 24 15 up up ADP news-003825 24 16 on on ADP news-003825 24 17 one one NUM news-003825 24 18 time time NOUN news-003825 24 19 zone zone NOUN news-003825 24 20 , , PUNCT news-003825 24 21 and and CCONJ news-003825 24 22 the the DET news-003825 24 23 brain brain NOUN news-003825 24 24 on on ADP news-003825 24 25 another another PRON news-003825 24 26 . . PUNCT news-003825 25 1 these these DET news-003825 25 2 peripheral peripheral ADJ news-003825 25 3 clocks clock NOUN news-003825 25 4 in in ADP news-003825 25 5 the the DET news-003825 25 6 body body NOUN news-003825 25 7 ’s ’s PART news-003825 25 8 organ organ NOUN news-003825 25 9 systems system NOUN news-003825 25 10 can can AUX news-003825 25 11 not not PART news-003825 25 12 themselves themselves PRON news-003825 25 13 receive receive VERB news-003825 25 14 information information NOUN news-003825 25 15 directly directly ADV news-003825 25 16 . . PUNCT news-003825 26 1 to to PART news-003825 26 2 know know VERB news-003825 26 3 what what DET news-003825 26 4 time time NOUN news-003825 26 5 of of ADP news-003825 26 6 day day NOUN news-003825 26 7 it it PRON news-003825 26 8 is be AUX news-003825 26 9 in in ADP news-003825 26 10 relation relation NOUN news-003825 26 11 to to ADP news-003825 26 12 the the DET news-003825 26 13 external external ADJ news-003825 26 14 environment environment NOUN news-003825 26 15 , , PUNCT news-003825 26 16 these these DET news-003825 26 17 tissues tissue NOUN news-003825 26 18 depend depend VERB news-003825 26 19 on on ADP news-003825 26 20 signals signal NOUN news-003825 26 21 originating originate VERB news-003825 26 22 in in ADP news-003825 26 23 the the DET news-003825 26 24 suprachiasmatic suprachiasmatic ADJ news-003825 26 25 nucleus nucleus NOUN news-003825 26 26 : : PUNCT news-003825 26 27 every every DET news-003825 26 28 day day NOUN news-003825 26 29 the the DET news-003825 26 30 brain brain NOUN news-003825 26 31 sends send VERB news-003825 26 32 signals signal NOUN news-003825 26 33 that that PRON news-003825 26 34 inform inform VERB news-003825 26 35 the the DET news-003825 26 36 peripheral peripheral ADJ news-003825 26 37 cells cell NOUN news-003825 26 38 to to PART news-003825 26 39 adjust adjust VERB news-003825 26 40 the the DET news-003825 26 41 phase phase NOUN news-003825 26 42 of of ADP news-003825 26 43 their their PRON news-003825 26 44 rhythms rhythm NOUN news-003825 26 45 , , PUNCT news-003825 26 46 like like ADP news-003825 26 47 the the DET news-003825 26 48 pin pin NOUN news-003825 26 49 of of ADP news-003825 26 50 a a DET news-003825 26 51 wrist wrist NOUN news-003825 26 52 watch watch NOUN news-003825 26 53 being be AUX news-003825 26 54 moved move VERB news-003825 26 55 a a DET news-003825 26 56 little little ADJ news-003825 26 57 bit bit NOUN news-003825 26 58 forward forward ADV news-003825 26 59 or or CCONJ news-003825 26 60 backward backward ADV news-003825 26 61 . . PUNCT news-003825 27 1 if if SCONJ news-003825 27 2 we we PRON news-003825 27 3 could could AUX news-003825 27 4 somehow somehow ADV news-003825 27 5 tinker tinker VERB news-003825 27 6 with with ADP news-003825 27 7 this this DET news-003825 27 8 system system NOUN news-003825 27 9 in in ADP news-003825 27 10 the the DET news-003825 27 11 adult adult NOUN news-003825 27 12 human human ADJ news-003825 27 13 , , PUNCT news-003825 27 14 it it PRON news-003825 27 15 might might AUX news-003825 27 16 be be AUX news-003825 27 17 possible possible ADJ news-003825 27 18 to to PART news-003825 27 19 reduce reduce VERB news-003825 27 20 the the DET news-003825 27 21 effects effect NOUN news-003825 27 22 of of ADP news-003825 27 23 jet jet NOUN news-003825 27 24 - - PUNCT news-003825 27 25 lag lag NOUN news-003825 27 26 and and CCONJ news-003825 27 27 shift shift VERB news-003825 27 28 work work NOUN news-003825 27 29 by by ADP news-003825 27 30 rapidly rapidly ADV news-003825 27 31 adjusting adjust VERB news-003825 27 32 our our PRON news-003825 27 33 internal internal ADJ news-003825 27 34 clock clock NOUN news-003825 27 35 . . PUNCT news-003825 28 1 duffield duffield PROPN news-003825 28 2 and and CCONJ news-003825 28 3 the the DET news-003825 28 4 team team NOUN news-003825 28 5 of of ADP news-003825 28 6 researchers researcher NOUN news-003825 28 7 may may AUX news-003825 28 8 have have AUX news-003825 28 9 uncovered uncover VERB news-003825 28 10 an an DET news-003825 28 11 important important ADJ news-003825 28 12 target target NOUN news-003825 28 13 for for ADP news-003825 28 14 such such ADJ news-003825 28 15 remedies remedy NOUN news-003825 28 16 by by ADP news-003825 28 17 identifying identify VERB news-003825 28 18 the the DET news-003825 28 19 id2 id2 NOUN news-003825 28 20 gene gene NOUN news-003825 28 21 , , PUNCT news-003825 28 22 which which PRON news-003825 28 23 appears appear VERB news-003825 28 24 to to PART news-003825 28 25 in in ADP news-003825 28 26 some some DET news-003825 28 27 way way NOUN news-003825 28 28 regulate regulate VERB news-003825 28 29 the the DET news-003825 28 30 magnitude magnitude NOUN news-003825 28 31 of of ADP news-003825 28 32 response response NOUN news-003825 28 33 of of ADP news-003825 28 34 the the DET news-003825 28 35 circadian circadian ADJ news-003825 28 36 clock clock NOUN news-003825 28 37 to to ADP news-003825 28 38 light light ADJ news-003825 28 39 signals signal NOUN news-003825 28 40 . . PUNCT news-003825 29 1 the the DET news-003825 29 2 work work NOUN news-003825 29 3 was be AUX news-003825 29 4 supported support VERB news-003825 29 5 by by ADP news-003825 29 6 the the DET news-003825 29 7 royal royal ADJ news-003825 29 8 society society NOUN news-003825 29 9 , , PUNCT news-003825 29 10 the the DET news-003825 29 11 wellcome wellcome PROPN news-003825 29 12 trust trust PROPN news-003825 29 13 , , PUNCT news-003825 29 14 the the DET news-003825 29 15 theodora theodora PROPN news-003825 29 16 b. b. PROPN news-003825 29 17 betz betz PROPN news-003825 29 18 foundation foundation PROPN news-003825 29 19 , , PUNCT news-003825 29 20 the the DET news-003825 29 21 national national PROPN news-003825 29 22 institute institute PROPN news-003825 29 23 of of ADP news-003825 29 24 general general PROPN news-003825 29 25 medical medical ADJ news-003825 29 26 sciences sciences PROPN news-003825 29 27 and and CCONJ news-003825 29 28 notre notre PROPN news-003825 29 29 dame dame NOUN news-003825 29 30 . . PUNCT news-003825 30 1 _ _ PROPN news-003825 30 2 contact contact NOUN news-003825 30 3 : : PUNCT news-003825 30 4 giles giles PROPN news-003825 30 5 e. e. PROPN news-003825 30 6 duffield duffield PROPN news-003825 30 7 , , PUNCT news-003825 30 8 assistant assistant NOUN news-003825 30 9 professor professor NOUN news-003825 30 10 of of ADP news-003825 30 11 biological biological ADJ news-003825 30 12 sciences science NOUN news-003825 30 13 , , PUNCT news-003825 30 14 574 574 NUM news-003825 30 15 - - PUNCT news-003825 30 16 631 631 NUM news-003825 30 17 - - PUNCT news-003825 30 18 1834 1834 NUM news-003825 30 19 , , PUNCT news-003825 30 20 _ _ NOUN news-003825 30 21 " " PUNCT news-003825 31 1 duffeld.2@nd.edu duffeld.2@nd.edu PROPN news-003825 31 2 " " PUNCT news-003825 31 3 : : PUNCT news-003825 31 4 mailto:duffeld.2@nd.edu mailto:duffeld.2@nd.edu NUM news-003825 31 5 topicid topicid PROPN news-003825 31 6 : : PUNCT news-003825 31 7 31507 31507 NUM news-003825 31 8 home home NOUN news-003825 31 9 experts expert NOUN news-003825 31 10 nd nd PROPN news-003825 31 11 in in ADP news-003825 31 12 the the DET news-003825 31 13 news news NOUN news-003825 31 14 subscribe subscribe NOUN news-003825 31 15 about about ADP news-003825 31 16 us we PRON news-003825 31 17 for for ADP news-003825 31 18 the the DET news-003825 31 19 media medium NOUN news-003825 31 20 contact contact NOUN news-003825 31 21 office office NOUN news-003825 31 22 of of ADP news-003825 31 23 public public ADJ news-003825 31 24 affairs affair NOUN news-003825 31 25 and and CCONJ news-003825 31 26 communications communication NOUN news-003825 31 27 notre notre PROPN news-003825 31 28 dame dame PROPN news-003825 31 29 news news NOUN news-003825 31 30 500 500 NUM news-003825 31 31 grace grace NOUN news-003825 31 32 hall hall PROPN news-003825 31 33 notre notre PROPN news-003825 31 34 dame dame NOUN news-003825 31 35 , , PUNCT news-003825 31 36 in in ADP news-003825 31 37 46556 46556 NUM news-003825 31 38 usa usa PROPN news-003825 31 39 facebook facebook PROPN news-003825 31 40 twitter twitter PROPN news-003825 31 41 instagram instagram PROPN news-003825 31 42 youtube youtube PROPN news-003825 31 43 pinterest pinterest PROPN news-003825 31 44 © © NUM news-003825 31 45 2022 2022 NUM news-003825 31 46 university university PROPN news-003825 31 47 of of ADP news-003825 31 48 notre notre PROPN news-003825 31 49 dame dame PROPN news-003825 31 50 search search NOUN news-003825 31 51 mobile mobile ADJ news-003825 31 52 app app NOUN news-003825 31 53 news news NOUN news-003825 31 54 events event NOUN news-003825 31 55 visit visit VERB news-003825 31 56 accessibility accessibility NOUN news-003825 31 57 facebook facebook PROPN news-003825 31 58 twitter twitter PROPN news-003825 31 59 instagram instagram PROPN news-003825 31 60 youtube youtube PROPN news-003825 31 61 linkedin linkedin VERB