Notre Dame researcher offers perspective on microbial perchlorate reduction | News | Notre Dame News | University of Notre Dame Skip To Content Skip To Navigation Skip To Search University of Notre Dame Notre Dame News Experts ND in the News Subscribe About Us Home Contact Search Menu Home › News › Notre Dame researcher offers perspective on microbial perchlorate reduction Notre Dame researcher offers perspective on microbial perchlorate reduction Published: April 05, 2013 Author: William G. Gilroy This week’s editions of the journal Science include a perspective piece by University of Notre Dame researcher Rob Nerenberg on the microbial reduction of perchlorate. The piece offers comments on a new paper in the journal that changes several paradigms about perchlorate-reducing microorganisms. Nerenberg, an associate professor of civil and environmental engineering and earth sciences, points out that roughly 20 years ago, investigators discovered that perchlorate, a chemical widely used in rocket propellants and explosives, was present in many water supplies across the United States. Perchlorate can inhibit thyroid function, potentially leading to developmental problems in fetuses and infants. The public outcry led to intense research on perchlorate and its remediation. “Researchers became very interested in perchlorate-microorganisms for use in biotreatment systems,” Nerenberg said. “The perchlorate reducers were found to be ubiquitous in the environment. Perchlorate provided these microorganisms with energy for growth, just as oxygen helps humans obtain energy from our food. Perchlorate is a strong oxidant, like oxygen, and therefore can provide a significant amount of energy.” Robert Nerenberg Nerenberg notes that the previously known perchlorate-reducing bacteria were closely related to each other, and had a specialized two-enzyme pathway: one enzyme to reduce perchlorate to chlorite, a toxic byproduct, and a second enzyme to detoxify chlorite by splitting it into oxygen and innocuous chloride. The oxygen provided further energy for the bacteria. The new paper in Science reveals that the attribute for perchlorate reduction is not limited to a narrow group of microorganisms. Also, it can be done without the second detoxifying enzyme by using a chemical detoxification reaction. By following the authors’ strategy for culturing their microorganisms, researchers may find an even greater diversity of perchlorate reducers. “Since the new microorganism grows under conditions similar to early geologic times, the authors suggest that some microorganisms, like this one, may have developed the ability to use perchlorate before they were able to use oxygen,” Nerenberg said. “It could show how bacteria developed the ability to use strong oxidants before the atmosphere became aerobic.” Nerenberg has developed new types of perchlorate-reducing bioreactors including hydrogen-based, membrane-supported biofilm reactors and microbial fuel cells. He also has studied novel species of perchlorate-reducing bacteria that have unique kinetic behavior. Most recently, he is exploring the possible ecological role of the special second enzyme, called the chlorite dismutase, which has been found in non-perchlorate reducing bacteria. Contact: Rob Nerenberg, 574-631-4098, nerenberg.1@nd.edu Posted In: Research Home Experts ND in the News Subscribe About Us Related October 05, 2022 Astrophysicists find evidence for the presence of the first stars October 04, 2022 NIH awards $4 million grant to psychologists researching suicide prevention September 29, 2022 Notre Dame, Ukrainian Catholic University launch three new research grants September 27, 2022 Notre Dame, Trinity College Dublin engineers join to advance novel treatment for cystic fibrosis September 22, 2022 Climate-prepared countries are losing ground, latest ND-GAIN index shows For the Media Contact Office of Public Affairs and Communications Notre Dame News 500 Grace Hall Notre Dame, IN 46556 USA Facebook Twitter Instagram YouTube Pinterest © 2022 University of Notre Dame Search Mobile App News Events Visit Accessibility Facebook Twitter Instagram YouTube LinkedIn