key: cord-0008806-rda1k81w authors: nan title: Chromosomes and expression mechanisms date: 2002-02-07 journal: Curr Opin Genet Dev DOI: 10.1016/0959-437x(95)80019-0 sha: df051f16f872321c4e34582e7c14cb12ef855e54 doc_id: 8806 cord_uid: rda1k81w nan W, Suhadolnik RJ: HIV-1 Reverse Tran~ripta~e -Inhibition By 2',S '-Ofigoadenylates. Biochemistry 1993, 32:12112-12118 The DNA-Bending Protein HMG-1 Enhances Progesterone Receptor Binding to Its Target DNA Sequences Mapping Polycomb-repeessed Domains • in the Bitharax Complex Using in Vivo Formaldehyde Cross-linked Chromatin Interaction of the Yeast RAD7 and SIR3 Proteins: Implications for DNA Repair and Chromatio Structure Telomere Maintenance and • Gene Repre~ion: a Common End? DNA Targets for Cerlain BZIP Proleins Distinguished by an Intrinsic Bend Nuclensomal Location of the STE6 TATA Box and Mat Alpha 2p-mediated Repression suGF1 Binds in the Major Groove of its Oligo(dG)center Dol Ollgo(dC) Recognition Sequence and is Excluded by a Positioned Nuclensome Core Heat Shock Factor can Activate Transcription While Bound to Nuclensomal DNA in Saccharomyces-Cerevisiae A Role of Polycomb Group • • Genes in the Regulation of Gap Gene Expression In Drosophila Correlation Between DNA Bending and Transcriptional Activation at a Plasmid Promoter Analysis of Nucleosome A~embly and Histone Exchange Using Antibodies Specific for Acelylated H4 Five SWI/SNF Gene e• Products are Components of a Large Multisubunit Complex Required for Transcriptional Enhancement Mutatioos that Suppress the .P Deletion of an Upstream Activating Sequence in Yeast: Involvement of a Protein Kioase and Histoee H3 in Repressing Transcription in Hvo Competition Between Chromatin and Transcription Complex Assembly Regulates Gene Expression During Early Development Competition Between Chromatin and Tram~ription Complex Assembly Regulates Gene Expression During Early Development Efficient Transcription of a DNA Template Associated with Histone (H3 Center Dot H4)(2) Tetramers The RNA Polymerase I Transactivator Upstream Binding Factor Requires Its Dimerization Domain and Highmobility-group (HMG) Box 1 to Bend, Wrap, and Positively Supercoil Enhancer DNA Transcription Induces the Formation of a Stable RNA Center Dot DNA Hybrid in the Immunoglohulin Alpha Switch Region Silent Domains are A~sembled Continuously from the Telomere and are Defined by Promoter Distance and Strength, and by SIR3 Dosage Transcriptional Activation: a Way into the Packaging CRP Induces the Repositioning of MalT at the Escherichia Coli MalKp Promoter Primarily Through DNA Bending Silencing Speaks Up An Arcane Role of DNA in Transcription Activation. Pro( Nat/Acad Sci U S A Transcriptional • o Repression by Nucleosomes But not H1 in Reconstituted Preblastoderm Drosophila Chromatin Structural and Functional Characterization of the Human Decorin Gene Promoter -a HomoDurine-Honmnvrlmidine S1 Nuclease-Sensitive Region is Involved in Transcriptional Control The Drosophila Extra Sex Combs • Protein Cootains WD Motifs Essential for Its Function as a Repre~ " Homeotic Genes Gene Exl~esslon within a Chromatin Domain. the Role of Cure Histone Hyperacetylation The Enhancer-hlucking Suppressor of Hairy-wing Zinc Finger Protein of Drosophila Melanogaster Alters DNA Structure RAP1: a Protean Regulator in Yeast Temporal and Spatial /~sociation OF Histone-H2A Variant Hvl with Traascriptionally Competent Chromatin During Nuclear Development in Tetrahymena-thermophila Repression OF Basal Transcription by HMG2 is Counteracted by TFIIH-associated Factors in an ATP-dependent Process A Histone Octamer can Step Around a Transcribing Polymerase Without Leaving the Template Cooperative Bending of the 21-basepair Repeats OF the SV40 Viral Early Promoter by Human Spl UV Damage to DNA Strongly Influences Its Rotational Setting on the Histone Surface of Reconstituted Nuclensomes Epigenetic Switching of • Transcriptional States: cis-And trans-acting Factors Affecting Establishment of Silencing at the HMR Locus in Saccharomyces Cerevlsiae Analysis of the Competition Between Nuclensome Formation and Transcription Factor Binding A Short Purine Oligooocleotide Forms a Highly Stable Triple Helix with the Promoter OF the Murine C-elm-1 Prntooocogene Excision Close to Matrix Attachment Regions of the Entire Chicken Alpha-globin Gene Domain by Nuclease $1 and Characterization of the Framing Structures Renard ]P: Scaffold Attachment Regions Stimulate HSP70.I Expression in Mouse Preimplantation Embryos But not in Differentiated Tissues Histone H3 Amino • Terminus is Required for Telomeric and Silent Mating Locus Repression in YeasL Nature ONA Chaperons: a Solution to a Persistence Problem Cisplalin-DNA Adducts are Molecular Decoys for the Ribosomal RNA Transcription Factor HUBF (human Upstream Binding Factor) ATP-depsndent • Nuclensome Disruption at a Heat-shock Promoter Mediated by Binding of GAGA Transcription Factor Decoding the Nucleurome Functional Dissection of the Yeast • • CycB-Tupl Transcriptional Co-repressor Complex Rearrangement of the Histone H2A C-terminal Domain in the Nucleosome Posterior Transformation, Neurological Abnormalities, and Severe Hematopoietic Defects in Mice with a Targeted Deletion of the Bmi-1 Protooncogene Vanholde K: Gene Expression -Properly Preparing Promoters Role of the Hislone Amino Termini in Facilitated Binding of a Transcription Factor, GAL4-AH, to Nucleosome Cores Periodicity of DNA Bend Sites in Human Epsilon-glohin Gene Region -Possibility of Sequeuce-directed Nucleusome Phadng The Octameric Histone Core of the Nucleosome -Structural Issues Resolved Differential Binding of C-Myc and Max to Nucleosornal DNA Relinoic Acid Regulates Aberrant Nuclear Localization of PML-RAR(xin Acute Promyelucytic Leukemia Cells ONA Triple-Helix Specific Intercalalors as Antigene Eohaocers -Unfused Aromatic Cations The • Kriippel-a~ociated Box-A (KRAB-A) Domain of Zinc Finger Proteins Mediates Transcriptional Repression Architectural Transcription Factors Transcription: in Tune with Histones Sequence and Spalial Requirements for the Tissue. and Species-independent 3~-end Processing Mechanism of Plant MRNA Nucleosome Positioning oo Chicken and Human Globin Gene Promoters Invitro -Novel Mapping TechnicFles Transcription and transcription factors Related reviews: Structure and function of DNA-binding proteins Structure and function of transcriptional activation domains (pp 190-196)*; The Escherichia coil RNA polymerase a subunit: structure and function The RNA polymerase II carboxy-terminal domain: links to a bigger and better 'holoenzyme'? Differential DNA-Binding Specificily of the Engrailed Homeodomaln: the Role OF Residue 50 A Peptide Encoding the Clun Delta-domain Inhibits the Activity of a C-Jun Amino-Terminal Protein Kinase Expansion of CREB's DNA Recognition Specificity by Tax Results from Interaction with Ala-Ala-Arg at Positions 282-284 Near the ComerYed DNAbinding Domain OF CREB RNA Polymerase-&ssociated Protein Rap94 Confers Promoter Specificity for Initiating Transcription of Vaccinia Virus Early Stage Genes The Interaction of GATA-Binding Proteins and Basal Transcription Factors with GATA Box-Containing Core Promoters a Model of Tissoe-Specific Gene Expression A Mismatch Bubble in Doobie-Slranded DNA Suffices to Direct Precise Transcription Initiation by E.~herichia Colt RNA Polymerase Mutalioas in Sigma Factor that Affect the Temperature Dependence of Transcription from a Promoter, But not from a Mismatch Bubble in Double-stranded DNA Molecular Cloning of APRF, a Novel IFN-Stimulated Gene Factor 3 P91-Reiated Transcription Factor Involved in the Gel 30-Mediated Signaling Pathway beta-casein MRNA Sequesters a Single-stranded Nucleic Acid-binding Protein Which Negatively Regulates the Beta-casein Gene Promoter RNA Cleavage and Chain Elongation by Escherichia Colt DNA-Oependent RNA Polymerase in a Binary Enzyme RNA Complex. Pro(-Natl Acad Sci Transcriptional • Activation by CTF Proteins is Mediated by a bipartite Low-proline Domain Quantitative Studies of the Effect of HTLV-I Tax Protein on CREB Protein DNA Binding A New Bipartite DNA-Binding Domain -Cooperative Interaction Between the Cut Repeat and Homeo Domain of Ihe Cut Hondo Proteins EIA-• associaled P300 and CREB-a~uciated CBP Belong to a conserved Family of Coactivators Activation of CAMP and Milogen Responsive Genes Relies on a Common Nuclear Factor Aturnlc Slructore of the RovC Resolva~: a Hollkkly lunction-~cific Endonuclease from E. CNi Equivalent Mutations in the Two Repeats of Yeast TATA-binding Protein Confer Distinct TATA Recognition Specificities Specifk: Transcriptional Activation Invilro by the Herpes Simplex Virus Protein VP16 11~ E2A Gene Product Contains Two Separable and Functionally Distinct Transcription Activation Domains A TATA Sequence-Dependent Traascriptional Be~es6or Activity A..~oc'iated with Mammalian Tran~ription Factor liA Retiooic Acid Incku:tion of Human Cellular Retinoic Acidbinding Protein-II Gene Transcription is Mediated by Retinoic Acid Receptor Retinoid X Receptor Heterodimers Bound to One Far Upslream Retinoic Acid-responsive Element with 5.ba~e Pair Spacing Mot1, a Global Repce~ur of RNA Polymerase II Transcription, Inhibits TBP Binding to DNA by an ATe-dependent Mechanism The Arabidopsls Thaliana Apurinic Endonuclease Arp Reduces Human Transcription Factors Fos and Jun Ghysdael h DNA-Biodieg and Transcriptional Activation Properties OF the Ews-Fli-1 Fusion Protein Resulting from the T(1122) Translocation in Ewing Sarcoma Recognition OF DNA by Gal4 in Solution -use of a M~ric Protein-DNA Complex fur Study by NMR Interaction of Human Thyroid Hormone Receptur-heta with Transcription Factor TFIIB May Mediate Target Gene Derepremion and Activation by Thyroid Hormone Encounters of Saccharomyces-cerevisiae RNA Polymerase-III with Its Transcription Faclors During RNA Chain Elongation Yeast Nudeotide Excision Repair Proteins Rad2 and Rnd4 Interact with RNA Polymerase II Yeast Raids Protein Binds Directly to Both Ssl2 and Ssll Proteins -Implicalim~ for the Structure and Fuoctioo of Transcription/Repair Factor B The POZ Domain: a Conserved Protein-protein Interaction Motif A Proteolytic Fragment from the Central Region of P53 Has Marked Sequence-Specific DNA-Bindiog Activity when Generated from Wild-Type But not from Oncogenlc Mutant P53-Protein Probing Close DNA Contacts of RNA Polymerase III Transcription Complexes with the Photuactive Nucleoside 4-tbiodeoxythymidine TyrOsine Phnsphorylation of Mammalian RNA Polymerase-II CarboxyI-Terminal Domain Refined Solution Structure of the Glucocorticnid Receptor DNA-Bindiog Domain Shortrange DNA Looping by the Xenopus HMGbox Transcription Factor Cooperative Binding of an Ultrabitborax Hom~ndomain Protein to Nearby and Distant DNA Sites Base Preferences for DNA Binding by the BHLH-Zip Protein USF: Effects of MgCL2 on Specificily and Comparison with Binding of Myc Family Secondary Structure and Interaction of Phage D108 Nee Repressor with a 61-base-pair Operator:. Evidence for Altered Protein and DNA Structures in the Complex Raman Spectral Studies of Nuc|eic Acids. 47. an Altered Specificity Mutation in the Lambda Repcessor Induces Global Reorganization of the Protein-DNA Interface The Sua8 Suppressors of Saccharomyces-Cerevisiae Encode Replacements of Conserved Residues Within the Largest Subunlt of RNA Polymerase-II and Affect Transcription Start Site Selection Similarly to Sua7 (Tfiib) Mutations Formation of a Monomeric DNA Binding Domain by Skn-1 BZIP and Humeodomain Elements Geuelic Analysis Indicates • that the Human Foamy Virus Bel-1 Protein Conlains a Transcription Activation Domain of the Acidic Class. l Viro11994 Mutallonal • Analysis of the Trar-~riplional Aclivation Domain of RelA: Identification of a Highly Synergistic Minimal Acidic Activation Domain Domain • • Organization of RNA Polymerase Alpha Subunit: C-terminal 85 Amino Acids Constitute a Domain Capable of Dimerizalion and DNA Binding Specific Interaction of IHF with RIBs, a Cia~ of Bacterial Repetitive DNA Elements Located at the 3' End of Transcription Units Interactions Between DNA-Bound Trlmers of the Yeast Heat Shock Factor A Single Amino-Acid Substitution in the Els Domain Alters Core DNA Binding Specificity of Etsl to Ihat of the Related Transcription Factors Elf1 and E74 Mapping Critical Residues in Eukaryotic DNA-binding Proteins: a Plasmid-based Genetic Selection Strategy with Application to the Oct-2 POU Motif Bipartite DNA Recognition by the Human Oct-2 Pou Domain -Pou(S)-Specific Phosphate Contacts are Analogous to those of Bacteriophage Lambda Repressor RNA Polymezase-II Transcription Faclor-SIIL 1. Identification, Purification, and Properties RNA Polymerase-II Transcription Factor-Sill. 2. Functional Properties and Role in RNA Chain Elongation Identificalion of a Novel Determinant for Basic Domain-Leucine Zipper DNA Binding Activity in the Acute-Phase Inducible Nuclear Faclor-lnterleukin-6 Transcription Factor Mol Cell BiD/1993, 13:7200, Bresnick EH, Felsenteld G: Dual Promoter Activation by the Human Bela-Globin Locus Control Region The Leucine Zipper is Necessary for Stabilizing a Dimer of the Helix-Ioop-hellx Transcription Factor USF But not for Maintenance of an Elongated Conformation Conformational Changes in E.coli RNA Polymerase During Prornoter Recognition HEN1 Encodes a 20-kilndalton Phnsphoprotein that Binds an Extended E-box Motif as a homodimer Factor C, the Specific Initiation Component of the Mouse RNA Polymerase I hoioenzyme, is Inactivated Early in the Transcription Process The Basics of Basal Transcription by RNA Polymerase I1 Basal Promoter and Enhancer Element of Yeast U6 SnRNA Gene Thermal Energy Requirement for Strand Separation During Transcription Initiation: the Effect of Supercniling and Extended Protein DNA Contacts Promoter Structure, Promoter • • Recognition, and Transcription Activation in Prokaryotes Transcription -Simplifying the Complex The HLEF/TCF-1-alpha HMG Protein Contains a Context-Dependeot Transcriptional Activation Domain that Induces the TCR Alpha Enhancer in T-Cells Functional and Biochemical Interaction of the HTLV-I Tax1 Transactivatur with TBP Cooperative Binding of Ga-Binding Protein Transcription Factors In Duplicated Transcription Initiation Region Repeats of the Cytochrome C Oxldase Subunit IV Gene The Drusophila-copia Retrotransposon Contains Binding Sites for Transcriptional Regulation by Humeoproteins RNA Template-directed RNA Synthesis by T7 RNA Polymerase The X-Ray Structure of an Atypical Homeodomain Present in the Rat Liver Transcription Factor LFB1/HNF1 and Implications for DNA Binding Identification and Purification of a Yeast Protein that Affects Elongation by Pax-3 DNA Interaction: Flexibility in the DNA Binding and Induction of DNA Cooformational Changes by Paired Domains New Models for Ihe Mechanism of • • Transcription Elongation and Its Regulation The DNA Binding Specificity of Ultrabithorax is Modulated by Cooperative Interactions with Extradenticle, Another Homeoprotein Properties of Initiat0r-Assoclated Transcription Mediated by GAL4-VP16 Human Thymidine Kinase CCAATbinding Protein is NF-Y, whose a Subunit Expression is Serum-dependent in Human IMR-90 Diploid Fibroblasts Trypanosoma Brucei RNA Polymerase II is Phosphorylated in the Absence of CarboxyI-Terminal Domain Heptapeptide Repeats Assembly of Recombinant TFIID Reveals Differential Cuactivator Requirements for Distinct Transcriptional Activators Subunit Dissociation Affects DNA Binding in a Dimeric Lac Repsessor Produced by Cterminal Deletion Multimerization of the Drosophila. Zest• Protein is Required for Efficient DNA Binding Assembly of Recombinant TFIID Reveals Differential Coaclivator Requirements for Distinct Transcriptional Activators An RNA-Binding Peptide from Bovine Immunodeficiency Virus TAT Protein Recognizes an Unusual RNA Structure The Retinobiastoma Gene Product RB Stimulates Spl-mediated Transcription by Liberating Spl from a Negative Regulator Cooperative DNA Binding of P53 with TFIID (TBP) -a Possible Mechanism for Transcriptional Activation Identification of the Target of ee a Transcription Activator Protein by Protein-protein Pholocrosslinking Identification of the C-terminal Activator Domain in Yeast Heat Shock Factor -Independent Control of Transient and Sustained Transcriptional Activity The Structure of Bacteriophage T7 Lysozyme, a Zinc Amidase and an Inhibitor of T7 RNA Polymerase Effects of Minor Groove Binding Drugs on the Interaction of TATA Box Binding Protein and TFIIA with DNA DNA Recognition by the NIT2 Nitrogen Regulatory Protein -Importance of the Number, Spacing, and Orientation of GATA Core Elements and Their Flanking Sequences Upon NIT2 Binding Targeting of SIR1 Protein Establishes Transcriptional Silencing at HM Loci and Telomeres in Yeast Crystal ee Structure of a P53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations A Portion of RNA Polymerase-II Molecules Has a Component Essential for Stress Responses and Stress Survival Eukaryutic Activators Function During • • Multiple Steps of Preinitiation Complex Assembly Eukacyotic Activators Function During • Multiple Steps of Preinitiation Complex Assembly Purified Yeast RNA Polymerase-II Reads Through Intrinsic Blocks to Elongation in Response to the Yeast TFIIS Analogue, P37 Sitedirected Mutagenesis Study on DNA Binding Regions of the Mouse Humologue of Suppressor of Hairless Biochemical Studies on Capped RNA Primers Identify a Class of Oiigooncleofide Inhibitors of the Influenza Virus RNA Polymerase Cleavage of the Nascent Transcript Induced by TFIIS is Insufficient to Promote Read-through of Intrinsic Blocks to Elongation by RNA Polymerase II SRY Protein Enhances Transcription of Fns-related Antigen 1 Not2(Cdc36), Not3, and Not4 Encode a Global-Negative Regulator of Transcription thai Differentially Affects Tara-Element utilization Small Nuclear RNA Genes Transcribed by Eilher RNA Polymerase II or RNA Polymerase III in Monocut Plants Share Three Promoter Elements and use a Strategy to Regulate Gene Expression Different from that used by Their Dicol Plant Counterparts DNA Binding and Bending Properties of the Postmeiotlcaily Expressed Sty-related Protein Sox-S Mutations in the Zinc-Finger Region of the Yeast Regulatory Protein Adrl Affect Both DNA Binding and Transcriptional Activation The RNA Polymerase Transcription Factor UBF is a sequence-tolerant HMG-box Protein that can Recognize Structured Nucleic Acids Conserved and Nonconserved Functions of the Yeast and Human TATA-binding Proteins Calcium/Calmudulin Inhibition of Basic-Helix-Loop-Helix Transcription Factor Domains Stimulation of GAl.4 Derivative Binding Io Nuclenso~l DNA by the Yeasl SWI/SNF Complex Topological Localization of the Human Transcription Factors IIA, liB, TATA Boxbinding Protein, and RNA Polymerase II-assucialed Protein 38 on a Class II Promoler Transcriptional Repression by the Human Bzip Factor E4Bp4 -Definition of a Minimal Repre~ion Domain Binding of Encephalomyocarditis Virus RNA Polymerase to the 3'-noncoding Region of the Viral RNA is Specific and Requires the 3'-poly(A) Tail Does HIV-1 Tat Induce a change in Viral • Initiation Rights? Cell DNA Sequence Recognition hy Pax Proteins -Bipartite Structure of the Paired Domain and Its Binding Site Biochemical Characlerization nf Binding of Multiple HIV-1 Rev Monomeric Proteins to the Rev Responsive Element Perturhalion of the Carboxy Terminus of HIV-1 Rev Affects Multimerization on the Rev Responsive Element Coupling of RNA Displacement and Intrinsic Termination in Transcription from Synthetic RNA Center Dot DNA Bubble Duplex Constructs RNA Displacement Palhways During Transcription from Synthetic RNA-DNA Bubble Duplexes HTFIIA/alpha, Encodes Both the P35 and P19 Subunits of Human TFIIA DNA-Binding Specificity of the S8-Homeodomain The Funclion of Individual Zinc Fingers in Sequence-Specific DNA Recognition by Transcription Factor-IliA Chemical Synthesis of a Fully Active Transcriptional Repressnc Protein Activation of the Beta-Globin Promoter hy the Locus Control Region Correlales wilh Binding of a Novel Factor Io the CAAT Box in Murine Erythroleukemia Celk But not in K562 Cells A Role for the H4 Subunit of Vaccinia RNA Polymerase in Transcription Initiation at a viral Early Promoter Control of Transcription Proce~ivity in Phage Lambda: Nus Factors Strengthen the Termination-resistant State of RNA Polymerase Induced by N antiterminator • Stimulation of RNA Polymerase II Elongation by Chromo~n~l Protein HMG-14 Oncogenic Truncation of the Firsl Repeal of C-Myb Decreases DNA Binding Invitro and Invivo Regulation of Parathyroid Hncmoue-related Protein (PTHrP) Gene Expression -Spt Binds Through an Inverted CACCC Motif and Regulates Promoter Activity in Cooperation with Etsl Amino-Terminal Amino Acids Modulate Sigma-Factor DNA-Binding Activity Transcript Cleavage by RNA Polymerase II Arrested by a Cyclobutane Pyrimidine Dimer in the DNA Template Nucleotide-specific Transcriptional Pausing in the PyrBI Leader Region of Escherichia Colt K-12 The Enhancer of Position-Effect Variegation of Drosophila, E(var)3-93D, Codes for a Chromatin Protein Containing a Conserved Domain Common to Several Transcriptional Regulators Vales LD: The Recomblnalion Signal Sequence-Binding Protein Rhp-2N Functions as a Transcriptional Rel~res~0r Distinguishable Patterns of Protein-ONA Interactions Involving Complexes of Basic Helix-Loop-Helix Proteins Interaction of the BHLHzip Domain of C-Myc with H1-Type Peptides -Characterization of Helicity in the Ht Peptides by NMR Dual Role of Tfiih in DNA Excision Repair and in Transcription by RNA Polymerase II Where Transcription Meets Repair Gata-Type Zinc Finger Multi-Containing Sequences and Chorion Gone Transcription Factors of the Silkworm Bombyx Mort DNA Recognition by Splicing Variants of the Wiln~' Tumor Suppressor, WT1 6-dichloro-l-hetad-rlbofuraoosylhenzimidazole and Isoquiooliue Sulfonamide Derivatives (H-8 and H-7*) Promote Dephosphorylation of the Carboxyl-terminai Domain of RNA Polymerase I Largest Subunit A Correlation Between Dexamethasone Inducibility and Basal Expression Levels of Retroviral Vector Proviruses Sequence-Specific, Single-Strand Binding Protein Activates the Far Upstream I:lement of C-myc and Defines a New DNA-Binding Motif Spl is Essential for Both Enhancer-Mediated and Basal Aclivatioo of the Tata-Less Human Adenosine Deaminase Promoter DNA-binding and Trans-activation Properties of Drosophila E2F and DP Proteins RNA Polymerase Locations in the Simian Virus-40 Transcription Complex Molecular Cloning and Functional Anal of the Adenovirus E1A-A~ociatnd 300-kD Protein (P300) Reveals a Prutein with Properties of a Transcriptional Adaptor Outside and Downstream of the Homeobox A Key Transcription Fac'lor for Eukaryotic Initiation Factor-2 Alpha is Strongly Homologous to Developmental Transcription Factors and May Link Metabolic Genes to Cellular Growth and Development A Structural Model for Fidelity in Transcription The Saccharomyces Cerevisiae seT8 Gene Encodes a very Acidic Protein that is Functionally Related to SeT3 and TATA-binding Protein Prolein-DNA Interactions Within DNase I-hypersensitive Sites Located Downstream of the HIV-1 Promoter Crystal • Structure of Transcription Factor E47: E-box Recognition by a Basic Region Helix-loop-helix Dimer Stalling of Escherichia Colt RNA Polymerase in the +6 to +12 Region in Vivo is Associated with Tight Binding 1o Consensus Promoter Elements Species-Specific Interaction of the Glutamiue,Rich Activation Domains of Spl with the Tara Box-Binding Protein Identification of a Pax Paired Domain Recognition Sequence and Evidence for DNA-Dependent Conformational Changes Multiple RNA Polymerase Conformations and GreA -Control of the Fidelity of Transcription Plant Activating Sequences: Positively Charged Peptides are Functional as Transcriptional Activation Domains Dynamic Aspects of DNA/Protein Interactions in the Transcriptional initiation Complex and the Hormone-Responsive Domains of the Phusphoenolpyruvate Carboxykinase Promoter Invivo Rhodes Implications for Transcriptional Control at the Level of Subunit Dimerization Zahler SA: Mutations in the Gene for a TRNA thai Functions as a Regulator of a Transcriptional Altenuator in Bacillus Subtills Basic-Helix-Lool~Hellx Transcription Factor and Sterol Sensor in a Single Membrane-Bonnd Molecule The High Mobility Group Protein HMG1 can Reversibly Inhibit Cl~ II Gene Tramcription by Interaction with the TATA-bindlng Protein RG: Purification, Cloning, and • Characterization of a Human Coactivalor, PC4, that Mediates Transcriptional Activation of Clas~ II Genes Homeodomaln-DNA Recognition The Zinc Finger Region of the Adenovirus-EIA Transactivating Domain Complexes with the TATA Box Binding Protein GEBF-I Activates the Drosophila Sgs3 Gene Enhancer by Altering a Positioned Nocleusemal Core Particle Transcriptional Activation Modulated by Homopolymeric Glutamine and Proline Stretches Characterization of Transcription Initiation, Translation Initiation, and POly(A) Addition Sties in the Gene-Siz@ Macronuclear DNA Molecules of Euplotes Synergism Between Tat and VP16 in Tran~-Activation of HIV-1 LTR Polymerase Processivily and Termination on Drosophila Heat Shock Genes Evidence for a Protein Domain Superfamily Shared by the Cyclins, Tfiib and Rb/P107 LEF-I Contains an Activation Domain that Stimulates Transcription Only in a Specific Context of Factur-Binding Sites Distinct DNA-Binding Properties of the High Mobility Group Domain of Murine and Human SRY Sex-Determlning Factors A Glutamine-• • rich Hydrophobic Patch in Transcription Factor Spl Contacts the DTAFIIt 10 Component of the DrOSophila TFIID Complex and Mediales Transcriptional Activation dorsal, a Drosophila Rellike Protein, is Phnsphorylat@ Upon Activation of the Transmembraoe Protein Toll Drosophila TAF(II)40 Interacts with Both a VP16 Activation Domain and the Basal Transcription Factur Transcription Factors lie and IIH and ATP Hydrolysis Direct Promoter Clearance by RNA Polymerase II A Point Mutation at the Junction of Domain 2 Center Dot 3/2 Center Dot 4 of Transcription Factor Sigma(70) Abrogates Productive Transcription and Restores Its Expect@ Mobility on a Denaturing Gel Spatial Relationship Between Polymerase and Exonudease Active Sites of Phage T4 DNA Polymerase Enzyme Mitotic Repression of RNA Polymerase III Transcription in Vitro Mediated by Phnsphorylation of a TFIIIB Component Yeast A1 and Alpha-2 Homeodomain Proteins Form a DNA-Binding Activity with Properties Distinct from those of Either Protein Use of a Selection Technique to Identify the Diversity of Binding Sites for the Yeast RAP1 Transcription Factor Effect of Alkylating Agents on Initiation and Elongation of the Lac UV5 Promoter Short-range Repression Permits Multiple Enhancers to Function Autonornously Within a Complex Promoter Phosphorylalion Weakens DNA Binding by Peptides Containing Multiple SPKK Sequences Transcriptional • e Antitermination Positive Patches and Negative Noodles: a Linking RNA Processing to Transcription Electron Microscopic Studies of the Interaction Between a Bacillus Subtilis Alpha/beta-type Small, Acidsoluble Spore Protein with DNA: Protein Binding is Cooperative, Stiffens the DNA, and Induces Negative Supercoiling Nascenl RNA Cleavage by Arrest@ RNA Polymerase-II Does not Require Upstream Translocation of the Elongation Complex on DNA The Bzip Transactivator of Epstein-Barr Virus, BZLF1, Functionally and Physically Interacts with the P65 Sul~Jnit of NF-kappa B DNA Repair Gene RAD3 of S. Cerevisiae is Essential for Transcription by RNA Polymerase-II RAD25 is a DNA Helicase Requir@ for RNA Repair and RNA Polymerase II Transcription The Retinoblastoma Protein Binds E2F Residues Required for Activation Invivo and TBP Binding Invilro Faclor-Dependent Transcription Termination by Vaccinia RNA Polymerase -Kinetic Coupling and Requirement for ATP Hydrolysis Premature Termination of Tubulin • Gene Transcription in Xenopus Oocytes is Due to Procnoter-dependenl Disruption of Elongation Conformational Shifts Propagate from the Oligomerizalion Domain of P53 Io Its Tetrameric DNA Binding Domain and Restore DNA Binding to Select P53 Mutants Cooperativity in Vivo Between the E2 Transactivator and the TATA Box Binding Protein Depends on Core Promoter Structure. EMBO t Conserved Cut Repeats in the Human Cut Horneodomain Protein Function as DNA Binding Domains A Switch Between 2-Stranded, 3-Strand@ and 4-Stranded Coil@ Coils in GCN4 Leucine Zipper Mutants Crystal Structure • of the DNA-binding Domain of the Heat Shock Transcriplion Factor Deletion Analysis of the Lambda TR1 Termination Region . Effect of Sequences Near the Transcript Release Sites, and the Minimum Length of Rho-Dependent Transcripts Enhancement of Reporter Gene De Novo Methylation by DNA Fragments from the Alpha-fetoprotein Control Region Purification and Characterization of a General Transcription Factor, ATFB, from the Archaeon Methanncoccus-thermolitholrophicus Four Contigucxls Amino Acids Define the Target for Slreptolydigin Resistance in the Beta.Subunil of Escherichia-coli RNA Polymerase Heterndimerization of the Transcription Factors E2F-1 and DP-1 Leads to Cooperative Trans-Activation Suppression of Yeast RNA Polymerase III Mutations by the URP2 Gene Encoding a Protein Homologous to the Mammalian Ribosomal Protein $20 Suppression of Yeast RNA Polymerase III Mutations by FhI1, a Gene Coding for a Fork Head Protein Involved in RRNA Processing The Basic-Helix-Loop-Helix Domain of Drosophila Lethal of Scute Protein is Sufficient for Proneural Function and Activates Neurogenic Genes The Phnsphorylalion and DNA Binding of the DNA-Binding Domain of the Orphan Nuclear Receptor NGFI-B Activation by the Estrogen Receptor In Vitro Selection of Zinc Fingers with Altered DNA-binding Specificity DNA Sequence Requirements for Transcriptional Initiator Activity in Mammalian Cells The Transcription Factor TFIIS Zinc Ribbon Dipeptide Asp-Glu is Critical for Stimulation of Elongation and RNA Cleavage by RNA Polymerase II Proton and Nitrogen NMR Sequence, specific Assignments and Secondary Structure Determination of the Bacillus Subtilis SPO1-encoded Transcription Factor 1. Bio(hemisto/1994 Defective Transcriptional Activation by Diverse Vp16 Mutants Associated with a Common Inability to Form Open Promoter Complexes An Escherichia Colt RNA Polymerase Defective in Transcription Due to Its Overproduction of Abortive Initiation Products Identical Components of Yeast Transcription Factor-IIIB are Required and Sufficient for Transcription of TATA Box-Containing and TATA-Eess Genes Two Pathways for Serum Regulation of the C-fos Serum Response Element Require Specific Sequence Elements and a Minimal Domain of Serum Response Factor Two Pairs of Oppositely Charged Amino Acids from lun and Fos Confer Heterodimerization to GCN4 Leucine Zipper Double-stranded DNA Templates can Induce Alphahelical Conformation in Peptides Containing Lysine and Alanine: Functional Implications for keucine Zipper and Helix-loop.helix Transcription Factors Identification of C/EBP Basic Region Residues Involved in DNA Sequence Recognition and Half-Site Spacing Preference Complexes of Yeast RNA • Poiymerase II and RNA are Substrates for TFIIS. induced RNA Cleavage Myristylation-dependent Transactivation by FBR V-fos is Regulated by C/EBP Synergistic Activation of Transcription by Bacteriophage Lambda CI Protein and E-colt CAMP Receptor Protein The Delta Subunit of Bacillus Subtilis RNA Polymerase. an AIIosteric Effector of the Initiation and Core-recycling Phases of Transcription Visnalization of Single Molecules of RNA Polymerase Sliding Along DNA Phosphorylation of the Transcription Factor-PHO4 by a Cyclin-CDK Complex Stimulation of Polyomavirus DNA Replication by Wild-Type P53 Through the DNA-Binding Site Affinity Labeling and Measurement of DNA-Induced Conformation Change in RNA Polymerase II RNA Polymerase-IIA and Polymerase-IIO have Distinct Roles During Transcription from the TATA-Less Murine Dihydrofolate Reductase Promoter Direct Interaction of Human TFIID with the HIV-1 Traosactivator Tat Bacteriophagn-T4 AIc Protein -a Transcription Termination Factor Sensing Local Modification of DNA Maf Nuclear Oncoproteln Recognizes Sequences Related to an Ap-1 Site and Forms Heterodimers with Both Fns and Jun Multimerization of the Mouse Tara-Binding Protein (TBP) Driven by Its C-Terminal Conserved Domain Specificity and Mechanism of Thyroid Hormone Induction from an Octamer Response Element Direct Recognition of Initiator Elements by a Component of the Transcription Factor lid Complex Residues in the TATA-Binding Protein Required to Mediate a Transcriptional Response to Retinoic Acid in EC Ceils Functional Analysis of Drosophila Factor 5 (Trill), a General Transcription Factor RRN6 and RRN7 Encode Subunits of a n~ltlprotein Complex Essential for the Initiation of RDNA Transcription by RNA Polymerase I in Saccharomyces Cerevisiae Molecular Basis of the Activation of Basal Histone HI(0) Gene Expression Involvement of the Basic Repeat Domain of Tata-Binding Protein (TBP) in Transcription by RNA Polymerases I, II, and Ill Effects of Activation-defective TBP Mutations on Transcription Initiation in Yeast Transcriptional Activation in Yeast by the Proline-Rich Activation Domain of Human CTF1 Ctd-Like Sequences are Important for Transcriptional Activation by the Proline-Rich Activation Domain of Ctfl ProJine-rich Activator CTF1 Targets the TFIIB Assembly Step During Transcriptional Activation Kornberg RD: • A Multiprotein Mediator of Traoscriptional Activation and Its Interaction with the C-terminal Repeat Domain of RNA Polymerase II Kornberg RD: eo A Multiprotein Mediator of Transcriptional Activation and Its Interaction with the C-terminal Repeat Domain of RNA Polymerase II Functional Map of the • Alpha Sulxmit of Escherichia Colt RNA Polymerase The SRY High-Mobility-Group Box Recognizes DNA by Partial Intercalation in the Minor Groove -a Topological Mechanism of Sequence Specificity. Pro< Increased Recruitment of TATA-I~nding Protein to the Promoter by Transcriptional Activation Domains in Vivo • Crystal Structure of the Oct-1 POU Domain Bound to an Octamer Site: DNA Recognition with Tethered DNA-blndiog Modules CTCF, a Conserved Nuclear Factor Required for Optimal Transcriptional Activity of the Chicken Cmyc Gene, is an 11-Zn-Fioger Protein Differentially Expressed in Multiple Forms Hhat Qe Methylfransferase Flips Its Target Base Out of the DNA Helix Two Distinct Factors Bind to the Rabbit Uteroglobin TATA-box Region and are Required for Efficient Transcription Purification and Characterization of a 59-Kilodalton Protein that Specifically Binds to NF-happa-B-Binding Motifs of the Defense Protein Genes of Sascophaga-Peregrina (the Flesh FIy) Tfiid Sequence Recognition of the Initiator and Sequences Farther Downstream in DrOsophila Class II Genes The RNA Polymerase I Transactivalor Upstream Binding Factor Requires Its Dimerizatlon Domain and Highmobility-group (HMG) Box 1 to Bend, Wrap, and Positively Supercoll Enhancer DNA Novel Zinc Finger Motif in the Basal Transcriptional Machinery -3-Dimensional NMR studies of the Nucleic Acid Binding Domain of Transcriptional Elongation Factor TFIIS Nuclear Magnetic Resonance Solution Structure of the Fushi Tarazu Homeodomain from Drosophila and Comparison with the Antennapedia Homeodomain Prakash 5: The Saccharomycescerevislae DNA Repair Gene RAD25 is Required for Transcription by RNA Polymerase-II Two Nuclear Factor Binding Domains Activate Expression from the Human Amylold Betaprotein Precursor Promoter Similarity Belween a Ubiquitous Promoter Elernent in an Ancient Eukaryote and Mammalian Initiator Elements Interaction Between Heat Shock Factor and Hsp70 is Insufficient to Suppress Induction of DNA-binding Activity in Vivo Tata Box-Binding Protein (TBP) is a Constituent of the Polymerase I-Specific Transcription Initiation Factor Tif-IB (Sit) Bound to the RRNA Promoter and Shows Differential Sensitivity to TBP-Directed Reagents in Polymerase-I, Polymerase-II, and Polymerase-III Transcription Factors Proline-Rich Transcriptional Activation Domain in Murine Hoxd-4 (Hox-4.2) Willis h A Mutation in the 2nd Largest Subunit of Tfiiic Increases a Rate-Limiting Step in Transcription by RNA Po|ymerase-III NMR Evidence for the RNA Stem-Loop Structure Involved in the Transcription Attenuation of E.coli Trp Operon Inhibition of T7 and T3 RNA Polymerase Directed Transcription Elongation in Vitro Factor Independent Activation of rrnB el: an 'extended' Promoter with an Upstream Element that Dramatically Increases Promoter Strength In Vivo Trar-r.~crlptional Pausing and *• Cap Formation on 3 Drosophila Heat-shock Genes • DNA Recognition by I~-sheets in the Arc Repressor-operator Crystal Structure Transcription induces the Formation of a Stable RNA Center Dot DNA Hybrid in the Immunoglobulin Alpha Switch Region Pa|x) CO: Zinc Finger Phage -Affinity Selection of Fingers with New DNA-Binding Speciflcifies Yeast TAFIIs in a Molfisubunit Complex Required for Activated Transcription Yin-Yang-1 Activates the C-myc Promoter Hydrophoblc-Repeat Region of Sigma(S4) Transcriptional Activation: a Complex Puzzle with Few Easy Pieces Redox-dependent shift of OxyR-DNA Contacts Along an Extended DNA-bindiog Site: a Mechanism for Differelldial Promoter Selection Tramactivation by NF-IL6/LAP is Enhanced by Phosphorylation of Its Activation Domain A New Start Site for Escherichiacolt RNA Polymerase at an Engineered Short Region of Non+Complementarity in Double.Stranded DNA Transcriptional Protein Binding Domains Governing Basal Expression of the Rat Luteiniziog Hormone Receptor Gone Crystal Structure of the Adenovirus DNA Binding Protein Reveals a Hook-on Model for Cooperative DNA Binding Proximity Between Nucleutlde/dinucleofide and Metal Ion Binding Sites in DNA-Depeodent gNA Polymerase from Functional Dissection of the Yeast CycB-Tupl Transcriptional Co-repsessor Complex Bindlng Proteln+lndependent Initiation -YY1, TFIIB, and RNA Polymerase-II Direct Basal Transcription on Supercoiled Template DNA A Conserved Heptamer Motif for Ribosomal RNA Transcription Termination in Animal Mitochondria extradeuticle Raises the DNA Binding Specificily of Homeotic Selector Gone Products Correction of Xeroderma Pigmentnsom Repair Defect by Basal Transcription Factor BIf2 (Tfiih) How do Zn2Cys6 Proteins Distinguish Between Similar Upstream Activation Sites -Comparison of the DNA.Binding Specificity of the Gal4 Protein Invitro and Invivo Contribution of Individual Base Pairs to the Interaction of TFIIIA with the Xeonpus 55 RNA Gene Drosophila Taf(ll) t 50 -Similarity to Yeast Gone Tsm-1 and Specific Binding to Core Promoter DNA Role of the Histone Amino Termini in Facilitated Binding of a Trar-~ription Factor, GAL4-AH, to Nuclensome Cores A Small C-Terminal Region of 1he Escherichia-coli MalT Protein Contains the DNA-Biodiog Domain Prediction of the Folding Pathways and Structure of the GCN4 Leucine Zipper. I Mol Bin NRF-1, an Activator Involved in Nuclear-Mitochondrial Interactions, Utilizes a New DNA-Bioding Domain Conserved in a Family of Developmental Regulators Effects of Guanosine 3',5"-bisdlphosphale (ppGpp) on Rate of Transcriplion Elongation in Isoleucine-starved Escherichia CoIL Protein+DNA Recognition -New Perspectives and Underlying Themes NMR Evidence for Similarities Between the DNA-Binding Regions of Drnsopbila Melanogaster Heat Shock Factor and the Helix-Turn-Helix and HNF-3/forkhead Families of Transcription Factors HTLV-I Tax Protein Stirrmlation of DNA Binding of BZIP Proteins by Enhancing Dimerization p53 Domains: Structure, Oligomerlzation, and Transformation Termination of Transcription by RNA Polymerase III from Wheat Germ SREBP-1, a Membrane-Bound Transcription Factor Released by SleroI-Regulated Proteolysis Cooperative Interaction of Human HSF1 Heat Shock Transcription Factor with Promoter DNA Tegtmeyer P: p53 Domains -Identification and Characterization of 2 Autonomous DNA-Bindlog Regions Transcription Factor B (Tfiih) is Required During Nucleotide-Excision Repair in Yeast Differential Binding of C-Myc and Max to Nocleo+~mr'nat DNA Locu6-specific Variation in Pho~horylation Slate of RNA Polymerase II in Vivo Correlations with Gone Activily and Transcript Processing Cloning and Expression of Drosophila TAF(II)60 and Human TAF(II)70 Reveal Conserved Interactions with Other Subunils of TFIID Interaction Between a Complex of RNA Polymerase-III Subunits and the 70-kDa Component of Transcription Factor-IIIB Specificity Determinants for Ihe Interaction of tambda Represser and P22 Represser Dimers Differential Regulation of RNA Polymerases I, II, and III by the TBP,blnding Represser Dr1 Hydrolytic Cleavage of Nascenl RNA in RNA Polymerase-III Ternary Transcription Complexes A Sigma(54) Transcriptional Activator Also Functions as a Pole-specific Repcessor in Caulobacter Spatial and Temporal Phosphorylation of a Transcriptional Activator Regulates Pole*Specific Gone Expression in Caulohacter Gone Expression Mediated by Bacteriophage T3 and T7 RNA Polymerases in Transgenlc Trypanesomes Transformation by Fns Proteins Requires a C-Terminal Transactivation Domain. Me/ Cell Bio11993 High Affinily Interaction of Dipteran High Mobility Group (HMG) Proteins 1 wilh DNA is Modulated by COOH.Terminal Regions Flanking the HMG Box Domain The Kruppel-associated Box-A (KRAB-A) Domain of Zinc Finger Proteins Mediates Transcriptional Repression Interplay of Heterogeneous Transcriptional Start Sites and Translational Selection of Augs Dictate the Production of Mitochondrial and Cytnsolic Nuclear TRNA Nudeotidyltransferase from the Same Gene in Yeast Transcription: in Tune with the Histones Architectural Transcription Factors The Domain Structure of Sigma $4 as Determined hy Analysis of a Set of Delelion Mutants TBP-DNA Inleractions in the Minor Groove Discriminate Between A:T and T:A Base Pairs Cooperative Binding of ETS-I and Core Binding Factor to DNA CCAAT Box Binding Prolein NF-Y Facilitates in Vivo Recruitment of Upstream DNA Binding Transcription Factors The Transcription Factor HNF1 Acts with C/EBP Alpha to Synergistically Activate the Human Albumin Promoter Through a Novel Domain A Highly Conserved Domain oe of RNA Polymerase II Shares a Functional Elemenl with Acidic Activation Domains of Upstream Transcriptional Factors The • Upstream Activator CTF/NF1 and RNA Polymerase Share a Common Element Involved in Transcriptional Activation Binding of Basal Transcription Factor TFII H to the Acidic Activation Domains of VP16 and P53 Mutations in Yeast HAP2/HAP3 Define a Hybrid CCAAT Box Binding Domain Subunit Interaction in Ihe CCAAT-Bindiog Heteromeric Complex is Mediated by a Very Short Alpha-Helix in HAP2 Cloning and Identification of Testis-Specific Transcription Elongation Factor-S-II The Saccharomycescerevisiae cdc68 Transcription Activator is Antagonized by San1, a Protein Implicated in Transcriptional Silencing Functional Interaction of the V-Rel and C-Rel Oncoproteins with the TATA-BIOding Protein and Association with Transcription Factor-liB DNA-Binding, and Nuclear Localization Activities are Organized into Distinct Structural Domains • e Transcriptional Elongation by RNA Polymerase II is Stimulated by Transactivators Half-Site Arrangement of Hybrid Glucocorticoid and Thyroid Hormone Response Elements Specifies Thyroid Hormone Receptor Complex Binding to DNA and Transcriptiorlal Activity Structure-function Analysis of the TBP-binding Protein Dr(l) Reveals a Mechanism for Repression of Class II Gone Transcriplion DrOsophila TFIIA-L is Processed into Two Subunils that are Associated with the TBP/TAF Complex Molecular Cloning and Characterization of DTAF(II)30 Alpha and DTAF(II)30 Beta -2 Small Subunits of Drosophila TFIID Drosophila TFIIA Directs Cooperative DNA Binding with TBP and Mediates Transcriptional Activation SREBP-1, a Basic-Helix-l,onp-Helix-Leocine Zipper Protein thai Controls Transcription of Ihe Low Density Lipoprotein Receptor Gone The Yeast Activator HAP1 -a GAI,4 Family Member -Binds DNA in a Directly Repeated Orientation Functional and Physical Interaction Between P53 and BZLFt -Implicalions for Epstein+Barr Virus Latency The Major Histocompatibility Complex Class-II Promoter-Binding Protein RFX Chromosome End Formation and Internal Sequence Elimination as Alternative Genomic Rearrangements in the Ciliate Paramecium A Mismatch Recognition Defect in Colon Carcinoma Confers DNA Microsatellite Instability and a mutator Phenotype Atomic Structure of Ihe RuvC Resolvase: a Holliday Jonclion-specific Endonuclease from E.coli DNA Replication Triggered by Double-stranded Breaks in E.coli: Dependence on Homologous Recombinalion Functions DNA Damage-Inducible Replicalion of the Escherichia-coli Chromosome is Initiated at Separable Sites Within the Minimal OriC Roles of RuvA, RuvC and RecG Gene Functions in Normal and DNA Damage-induclble Replication of the Escherichia Coil Chromosome Detection of Nondlsjunction and Recombination in Meiotic and Postmeiotic Cells from XY(Sxr) {xy, Tp(Y)lCt] Mice Using Multicolor Fluorescence in Situ Hybridization Specific Complex Formation Between Yeast Rad6 and Rad18 Proteins -a Potential Mechanism for Targeting Rad6 Ublquitin.Conjugating Activity 1o DNA Damage Sites Binds Single-Stranded DNA Ends and Catalyzes DNA Renaturation and Strand Transfer Identification of Residues in the Mu Transposase Esseolial for Catalysis Yeast Nucleotide Excision Repair Proteins Rad2 and Rad4 Interact with RNA Polymera~e II Specific Cleavage of Model Recombinalion and Repair Intermediates by Ihe Yeast Radl-Radl0 DNA Endonuclease Yeast Rads Protein Binds Directly Io Both Ssl2 and Ssll Proteins -Implications for the Struclure and Function of Transcription/Repair Factor B DNA Repair Defects Associated with Chromosomal Translncation Breaksite Regions UVcatalyzed Cross-linking of Escherichia Coil Uracil-DNA Glycnsylase Io DNA -Identification of Amino Acid Residues in the Single-stranded DNA Binding Site The F-Ptasmid CcdB Protein Induces Efficienl ATP-Dependent DNA Cleavage by Gyrase. 1Mol Bio11993 Long-tract Milolic Gene Conversion in Yeast: Evidence for a Triparental Contribution During Spontaneous Recombination recA-Independent and RecA-Dependent Inlramolecular Plasmid Recombination -Differential Homology Requirement and Distance Effecl. l Mol Bio11994 Base Mutalion Analysis of Topoisomerase II-idarubicin.DNA Ternary Complex Formation. Evidence for Enzyme Subunit Cooperalivity in DNA Cleavage Two Related Recombinase~ are Required for Site-Specific Recombination at Dif and Cer in E.coli K12 Loeb LA: DNA Polymerase Delta is Required for Base Excision Repair of DNA Methylalion Damage in Saccharomyces Cervisiae DNA Topoisomerase-II and Casein Kinase-II Associate in a Molecular Complex thai is Catalylically Active S Region Transcription Per Se Promotes Basal IgE Class Switch Recombination But Additional Factors Regulale the Efficiency of Ihe Process V(D)I Recombination Coding Junction Formation withoul DNA Homology -Processing of Coding Termini Mutation in Ihe DNA Mismalch Repair Gene Homologue Hmlhl is Associated wilh Hereditary Non-Polyposk Colon Cancer Broverman [3A, Meneely PM: Meiotic Mutants that Cause a Polar Decrease in Recombination on the X-Chromnsorne in Caenorhabditis Elegans Unfolding of Nucleosome Cores Dramatically Changes the Dislribution of Ultraviolet Photoproducts in DNA Somatic Inactivation and Reactivation of Ac Associated with Changes in Cytosine Methylation and Transposase Expression Radding CM: Resolution of the Three-stranded Recombination Intermediate Made by RecA Protein -an Essential Role of ATP Hydrolysis Tethering Human Immu@eficiency Virus 1 Integrase to a DNA Site Directs Integrafion to Nearby Sequences An Interaction Belween the Mammalian DNA Repair Protein Xrccl and DNA Ligase-III Use of Genelic Recombination as a Reporter of Gene Expression A Novel Mutant Topolsomerase II Alpha Present in VP-16-resistant Human Melanoma Cell Lines Has a Deletion of Aianine 429 TCR Beta and TCR Alpha Gene Enhancers Confer Tissue-Specificity and Stage-Specificity on V(D)J Recombination Events Conformalional Drug Delerminants of the Sequence Specificity of Drug-gtimalated Topolsomerase-II DNA Cleavage The C-Terminal Domain of Saccharomyces Cerevisiae DNA Topoisomerase II The Rad16 Gene of Schiznsaccharomyces Pombe. a Homolng of Radl Gene of Saccharomyces Cerevisiae Imprecise Excision of the Caenorhabditis Elegans Tran~oson Tcl Creates Functional S' Splice Sites Anahaena-xisF Genc Encodes a Developmentally Regulaled Site-Speclfic Recombinase Induction of RNA-Binding Proteins in Mammalian Cells by DNA-Damaging Agenls Purification and Biochemical Charaderization of Escberichia Coli RecA Proteins Mutated in the Putative DNA Binding Site. I Bio/ Chem High Resolution Mapping of UV-lnduced Photoproducts in the Escherichia Coil Laci Gene -Inefficient Repair of the Non-Transcribed Strand Correlates with High Mutation Frequency Superoxlde Dismutase (sod-l) Null Mutants of Neornspora Crassa: Oxidative Stress Sensitivity, Spontaneous Mutation Rate and Response to Mutagens The Gene Encoding Topoisomerase II from Plasmodium Falcipamm Tbe Sepl Strand Exchange Protein from Saccharomyces Cerevislae Promntes a paranemic Joint Between Homologous DNA Molecules All FW: Mutations of the Intronic IgH Enhancer and Its Flanking Sequences Differentially Affect Accessibility of the J(H)-Lncus Two-dimensional H-I NMR Sludies of Immobile Holliday Junctions: Nonlabile Proton Assignments and Identification of Crossover Isomers Lambowitz AM: A Milochondrial Retroplasmid Integrates Mitochondtial DNA by a Novel Mechanism Involving the Synthesis of a Hybrid CDNA and Homologous Recombination Radding CM: Interactions of Three Strands in Joints Made by RecA Protein Lack of Transcription-Coupled Repair in Mammalian Ribosomal RNA Genes The Covalent Eukaryofic Topoisomerase-I-DNA Intermediate Catalyzes PH-dependent Hydrolysis and Alcoholysis Characterization of Inlramolecular and Intermolecular DNA Ligafion Mediated by Eukaryotic Topofsomerase-I -Role of Biparfile DNA Interaclion in the Ligation Process Cellular Responses to Cisplatin -the Roles of DNA-Bindiog Proteins and DNA Repair Evidence for a Mechanism Predisposing to Intergenerational CAG Repeal Instability in Spinncerehellar Ataxia Type-I Bacteriophage T4 and Human Type 1 DNA Ligases Relax DNA Under Joining Conditions Heal Stre~ Induces Hsc70/Nuclear Topoisomerase I Complex Formation in Vivo -Evidence for Hsc70-Mediated, ATP-Independent Reactivation in Vitro It Was a Very Good Year for DNA Repair Cla~ Switch Control Region at the 3' End of the Immunoglobulin Heavy Chain Locus In Vitro UV Mutagenesis As~.ociated with Nucleotide Excislon-Repair Gaps in Escherichia Coll Meiosls-Specific Formation of Joinl DNA Molecules Containing Sequences from Homologous Chromosomes Reverse Gyrase -a Helicase-Like Domain and a Type-I Topoisomerase in the Same Polypeptide Function of the Hydrophilic Carboxyl Terminus of Type-II DNA Topoisomerase from Drosophila.melanogaster. 1. Invitro Studies Processive Recombination by Wild-type Gin and an Enhancerindependent Mutant -insight into Ihe Mechanisms uf Recomblnalion Selectivity and Strand Exchange Rchl, a Protein that Specifically Interacts with the RAG-1 Recomhination-acfi~aling Protein Analysis of Regiom of RAG-2 Important for V(D)J Recombiuafioo DNA Double Helix Promntes a Linkage Isomerization Reaction in Trans.diamminedicbloroplatioont(ll)-modified DNA Copy-Choice Illegitimate DNA Recombination Revisited Phosphorylation of the C-terminal Domain of Yeast Topoisomerase II by Casein Kinase II Affects DNA-i~otein Interaction ger.cue of T Cell-specific V(D)J Recombination in SCID Mice by DNA-damaging Agents Frequent toss of the En Transposable Element after Excision and Its Relation to Chromosome Replication in Maize (Zea Mays L) Evidence of Selection for Protein Introus Inthe RecAs of Pathogenic Mycobacteria Growth Arrest by Induction of P83 in DNA Damaged Keratinocyles is Bypassed by Human Papillomaviros 16 E7 Preferential Repair of UV Damage in Highly Transcribed DNA Diminishes UV-Indoced Intrachromnsomal Recombination in Mammalian Cells Mismatch Repair of Helernduplex DNA Intermediates of Extrachromosomal Recombiualion in Mammalian Cells Mismatch Repair of Heteroduplex DNA Intermediates of Extrachromosomal Recombination in Mammalian Cells (voi 10 Nonhomologoos Recombinalion in Human Cells Region-Specific Aclivators of Meiotic Recombination in Schizosaccharomycespomhe Efficient Integration of Arlificial Transposons into Plasmid Targets in Vitro: a Useful Tool for DNA Mapping, Sequencing and Genetic Analysis Characterization of Two Protein Kinases from Schlzosaccharomyces Pombe Involved in the Regulation of DNA Repair Release of 5'-Terminal Deoxyribose-Phosphate Residues from Incised Ahasic Sites in DNA by the Escherichia Col] Recj Protein A Plant Scaffold Attached Region Detected Close to a T-DNA Integration Site is Active in Mammalian Cells DNA Topoisomerase-I Controls the Kinetics of Promoter Activation and DNA Topology in Saccharomycescerevisiae Reversible Inactivation of the Escherichia Col] RecBCD Enzyme by the Recombination Hotspot-chi Invitro -Evidence for Functional Inactivation or Loss of the RecD S~ubunit Resolution of Synthetic Chi-Structures by the FLP Site-Specific Recomblnase Substrate Specificity of the Escherichia-coli Endonuclease-III -Excision of Thymine-Derived and Cytoslne-Derived Lesions in DNA Produced by Radiation-Generated Free Radicals All 4 Known Cyclic Adducts Formed in DNA by the Vinyl Chloride Metabolite Chloroacetaldehyde are Released by a Humao DNA Glycnsylase The Recombination Signal Sequence-Binding Protein Rbp-2N Functions as a Transcriptional Represser Dual Role of TFIIH in DNA Excision Repair and in Transcription by RNA Polymerase II Where Transcription Meets Repair Repair of Oxidative Damage Within the Mitochondrial DNA of RINr-38 Cloning, Overexpfession, Purification, and Characterization of the Escherichia Col] Ruvc Holliday lunction Resolvase The UV Response Involving the Ras Signaling Pathway and Ap-1 Transcription Factors is Conserved Between Yeast and Mammals Dual Roles of a Multiprolein Complex from S-Cerevisiae in Transcription and DNA Repair Kornberg RD: eo Relationship of CDK-aclivating Kinase and RNA Polymerase II CTD Kinase TFIIH/TFIIK Hin Recombinase Bound tO DNA: the Origin of Specificily in Major and Minor Groove Interactions Sequences Affecting the V(D)J Recombinational Activity of the IgH Intronic Enhancer in a Transgenlc Substrate The Matlng-Type Locus of Cblamydomonas Reinhardtii Contains Highly Rearranged DNA Sequences Protein Homologs Required for the DNA Damage Checkpoint in Fission Yeast Stimulation of Sitespecific Topoisomerase II-mediated DNA Cleavage by an N-methylpyrrolecarboxamide-anilinuacridine Conjugate: Relation to DNA Binding Site-Specific Cleavage of a DNA Hairpin by Topoisomerase II -DNA Secondary Structure as a Determinant of Enzyme Recognitlon/Cleavage Distinct Roles for RAG-1 in the Initiation of V(D)J Recombination and in the Resolution of Coding Ends Metabolic Processing of Cyclobulyl Pyrimidine Dimers and (6-4) Photol)roducts in UV-Treated Human Cells -Evidence for Distinct Exclsion-Repalr Pathways Identification of Barriers to Rolalion of DNA Segments in Yeast from the Topology of DNA Rings Excised by an Inducible Site-Specific Recomblnase The lOl~,isomerase I Geue from Uslilago Maydis: Sequence, Disruption and Mutant Phenotype Coding End Sequence can Markedly Affect the Initiation of V(D)J Recombination Extent to Which Homology can Constrain Coding Exon Junctional Diversity in V(D)J Recombination Extent to Which Homology can Constrain Coding Exon Junctional Diversity in V(D)J Recombination Absence of a Ku-like DNA End Binding Activity in the Xrs Double-strand DNA Repair-deficient Mutant UVB-Induced DNA Breaks Interfere with Transcriptional Induction of C-los Site-specific Integration by Adenc~associated Virus is Directed by a Cellular DNA Sequence A Distant lO-bp Sequence Specifies the Boundaries of a Programmed DNA Deletion in Tetrahymena The Effects of Insertions on Mammalian Intrachromosomal Recombination Nonhomologoos DNA End Joining in SchiznsaccharomyceS Pombe Efficiently Eliminates DNA Double-strand-breaks from Haploid Sequences Golic KG: local Transposition of P elements in Drosophila Melanogaster and Recombination Between Duplicated Elements Using a Site-specific Recombinase The Role Of the Ameioticl Gene in the Initiation of Meiosis and in Subsequent Meiotic Events in Maize Transcription Factors liE and IIH eo and ATP Hydrolysis Direct Promoter Clearance by RNA Polymerase II Characterization of a Set of Integration Host Factor Mutants Deficient for DNA Binding Recombination Between Viral RNA and Transgenic Plant Transcripts DNA Mismatch Binding and Incision at Modified Guanine Bases by Extracts of Mammalian Cells -Implications for Tolerance to DNA Methylatlon Damage Incision at DNA G center Dot T Mispairs by Extracts of Mammalian Cells Occurs Preferenlially at Cytosine Methylation Sites and is not Targeted by a Separate G Center Dot T Binding Reaction M26 Recombinational Hotspot and Physical Conversion Tract Analysis in the Ade6 Gene of Schlzosaccharomyces Pombe Independent Control of Immunoglobolin Switch Recombinafiou at Individual Switch Regions Evidenced Through Cre-ioxP-Mediated Gene Targeting Drosophila Rrpl Complements E.coli Xlh Nfo Mutants -Prolectiou Against Both Oxidative and Alkylation-lnduced DNA Damage Mulattoes of Vaccinla Virus DNA Topoisomerase-I that Slabilize the Cleavage Complex DNA Repair Gene RAD3 of S. Cerevisiae is Essential for Transcription by RNA Polymerase-II RAD25 • is a DNA Helicase Required for DNA Repair and RNA Polymerase II Transcription Yeast Excision Repair Gene RAD2 Encodes a Single-Stranded DNA Endonuclease Holiday Junction Cleavage by Yeast Radl Protein Stalking the Elusive Recombination Intermediate Specificity of DNA Recognition in the Nucleoproteln Complex for Site-Speclfic Recombination by Tn21 Resolvase. Nuclei( Acids Res Homologous Pairing and Strand Exchange Promoted by the Escherichia Colt RecT Protein Complementalion of Bacteriophage Lambda Integrase Mutants -Evidence for an Intersobunll Active Site The Mechanism of Sequence-Specific DNA Cleavage and Strand Transfer hy Phi X174 Gene-A* Protein Recognition of Oxidized Abasic Sites by Repair Endonucleases The Characterization of a Mammalian DNA Structure-Specific Endonuclease Functional Domains Within FENt and RAD2 Define a Family of Structure-specific Endonucleases: Implications for Nucleotide Excision Repair Ends-in VS Ends-Out Recombination in Yeast Cloning the Drosophila Homolog of the Xeroderma Pigmentosum Complementation Group C Gene Reveals Homology Between the Predicted Human and Drosophila Polypeptides and that Encoded by the Yeast Rad4 Gene Decatenating Activity of Escherichla-coli DNA Gyrase and Topoisomerase-I and Topoisomerase-III During eriC and PBR322 DNA Replication Invitro Topoisomerase IV can Supporl eriC DNA Replication in Vitro Interchromosomal Exchange of a Large Subtelomeric Segment in a Plasmodium Falciparum Cross. EMBO I DNA Repair -Incisions for Excision Stalking the Elusive Recombination Intermediate -Response Analysis of the Mammalian Gadd45 Gene and Its Response to DNA Damage Flow Linear Dichroism and Electron Microscopic Analysis of Protein-DNA Complexes of a Mutant UvrB Protein that Binds to But Cannot Kink DNA Xubf, an RNA Polymerase I Transcription Factor, Binds Crossover DNA with Low Sequen(e Specificity Mutation of the Gene Encoding Protein Kinase C1 Stimulates Milotic Recombination in Saccharomyces Cerevislae Activity OF Calf Thymm DNA Helicase-E on Cisdiamminedichloroplalinum-(ll)-Damaged DNA Mixed Segregation and Recombination of Chromosomes and Yacs During Single.Division Meiosis in Spol 3 Slraios of Saccharomyces Cerevlsiae Moncollin V: p44 and P34 Subunits of the BTF2/TFIIH Transcription Factor have Homologies with SSLI, a Yeast Protein Involved in DNA Repair Resolution of Recombination Intermediates by a Mammalian Activity Functionally Analogous to Escherichia Colt Ruvc Resolvase Artificial Control of Nuclear Translucatiou of DNA Repair Methyltraosferase Transcription-coupled Repair of Psoralen Cro~-Iinks But out Monoadducts in Chinese Hamster Ovary Cells Mutations in Xrs2 and Rad50 Delay But do not Prevent Mating-Type Switching in Saccharomyces Cerevisiae Identifying the Catalytic Residue of the ATPase Reaction of DNA Gyrase On the Role of ATP Hydrolysis in RecA Protein-mediated DNA Strand Exchange. 3. Unidirectional Branch Migration and Extensive Hybrid DNA Formation Effects of Integration and Replication on Transcription of the HIV Long Terminal Repeat Retrotraosposition of a Marked Drosophila tine-like Element in Cells in Culture The Activity of the Saccharomyces-cerevisiae Strand Exchange Protein-1 Intrinsic Exonuclease During Ioint Molecule Formation Jest YC: Transient DNA Demethylation in Differentiating Mouse Myobiasts Cosrelates with Higher Activity of 5-methyldeoxycylldine Excision Repair A Multifunctional Exonoclease from Vegetative Schizosaccharomyces Pombe Cells Exhibiting in Vitro Strand Exchange Activity Schizosaccharomyces Pombe Fatty Acid Synthase Mediates DNA Strand Exchange in Vitro An Essential Gene, ESR1, is Required for Mitotic Cell Growlh, DNA Repair and Meiotic Recombination in Saccharomyces Cerevisiae Homologous Recombination of Monkey Alpha-satellite Repeats in an in Vitro Simian Virus 40 Replication System: Possible Association of Recombination with DNA Replication Saccharomyces Cerevisiae RAD52 Alleles Temperalure-ser-~tive for the Repair of DNA Double-strand Breaks Efficient Targeted Integration at Leu1-32 and Urn4-294 in Schizosaccharomyces Pombe Characterization of a Human DNA Damage Binding Protein Implicated in Xeroderma-plgmentos~um-E. I Linn 5: Correction of the DNA Repair Defect in Xeroderma Pigmeoto~.rn Group E by Injection of a DNA Damage-Binding Protein A Gene with Specific and Global Effects on Recombination of Sequences from Tandemly Repeated Genes in Saccharomyces Cerevislae Dissecting the Resolulion Reaction of Flntegrase Using Suicide Holllday Junction Substrates Characterization of (6-4) Pholoprnduct DNA Phololyase Growlh State-Dependent and Cell Cycle.Dependent Fluctuation in the Expression of 2 Forms of DNA Topoisomera~-II and Possible Specific Modification of the Higher Molecular Weight Form in the M-Phase DNA Strand Exchange in the Absence of Homologous Pairing Mechanisms of Camptothecin Resistance in Yeast DNA Topoisomerase.I Mutants Evidence for a Group li Intron in Escherichia Colt Inserted into a Highly Conserved Reading Frame A~ocialed with Mobile DNA Sequences DNA Rearrangement of the Shufflon Determines Recipient Specificity in liquid Mating of Incll Plasmid R64 Functional Characterization of Residues in the P-Loop Motif of the RecA Protein ATP Binding Site Efficiency of ATP Hydrolysis and DNA Unwinding by the RecBC Enzyme from Escherichia Coll Transcription Activates RecA-Promoted Homologous Fairing of Nucleosomal DNA A Role for RNA Synthesis in Homologous Fairing Events A Reverse Gyrase with an Unusual Structure -a Type-I DNA Topoisomerase from the Hypecthermophile Methanopyrus Kandleri is a 2-Subunit Protein Two Different Types of Double-strand Breaks in Saccharomyces Cerevisiae are Repaired by Similar RAD52-independent, Nonhomologous Recombination Events Identification of Human DNA Topoisocnera~-I as a Cofactor for Activator-Dependent Transcription by RNA Polymerase-II Effects of UwS, UwY and DNA Topol~merase on the Formation of Tandem Duplications OF the Eli Gene in Bactesiophage-T4 DNA-Induced Couformatioual Changes in RecA Protein -Evidence for StruCtural Heterogeneity Among Nucleoprotein Filaments and Implications for Homologous Pairing Differential Effects by the P21 CDK Inhibitor on PCNA-dependent DNA Replication and Repair Specificilies of Human, Rat and E.coli O-6-methylguanine-DNA Methyltransferases Towards the Repair of O-6-methyl and O-6-ethylguaoine in DNA 3-Dimenslonal Structure of the 67K N-Terminal Fragment of E. Colt DNA Topoisomerase-I Regulation of V(D)J Recombination Activator Protein RAG-2 by Phnsphorylation Cell Cycle Regulation of V(D)J Recomblnation-Activatiog Protein RAG-2 Transient, Meiosis-Induced Expression of the Rec6 and Rec12 Genes of Schiznsaccharomyces Pombe The Ionizing Radiation-Induced Replication Prnteln-A Phosphorylatlon Response Differs Between Ataxia Telangiectasia and Normal Human Cells The Chromosome End in Yeast -Its Mosaic Nature and Influence on Recombinational Dynamics A Sister-Strand Exchange Mechanism for RecA-Independent Deletion of Repeated DNA Sequences in Escherichia CoB Purification and Characterization of the Escherichia CoB Reco Protein -Renaturation of Complementary Single-Stranded DNA Molecules Catalyzed by the Reco Protein Use of an Inducible Site-Specific Recombinase to Probe the Structure of Protein-DNA Complexes Involved in F PJasmid Partition in Escherichia Coli Mutational Analysis of ERCC3, Which is Involved in DNA Repair and Transcription Initiation: Identification of Domains Essential for the DNA Repair Function The Relationship of Homologous Synapsis and Crossing Over in a Maize Inversion The V(D)I Recombination Signal Sequence and Kappa B Binding Protein RC Binds DNA as Dimers and Forms Multimeric Structures with Its DNA Ligands ADP-ribose) Molecules Formed During DNA Repair in Vivo Base Sequence-independent Distorsions Induced by Interstrand Cross-links in Cisdiaminedicblocoplatinum (ll)-modified DNA Rearrangement and Diversity of T-Cell Receptor Beta-Chain Genes in Thymocytes -a Critical Role for the Beta-Chain in Development Analysis of a Recombination Hotspol for Gene Conversion Occurring at the His2 Gene of Saccharomyces Cerevisiae Colnductlon of Cjun Gene Expsession and Internucleosornal DNA Fragmentation by Ionizing Radiation The Classical Human Phosphoglucomutase Isozyme Polymorphism is Generated by Intragenic Recombination Molecular Basis of Nitrogen Mustard Effects on Transcription Processes: Role of Depurination Structure of Recomblnants from Conjugational Crosses Between Escherichla Colt Donor and Mismatch-Repair Deficient Salmonella Typhim~Jrium Recipients Proliferating Cell Nuclear Antigen-dependent Abaslc Site Repair in Xenopus Laevis Oocytes: an Alternative Pathway of Base Excision DNA Repair Genetic Evidence for IS1 Transposition Regulated by InsA and the Delta InsA.B'-InsB Species, Which is Generated by Translation from Two Alternative Internal Iniliation Sites and Frameshiffing A Uniquely High Level of Recombination at the HLA-B Locus Xer-Mediated Site-Specific Recombination al Cer Generates Holllday Junctions in Vivo Unrepaired Heteroduplex DNA in Saccharomyces Cerevislae is Decreased in RAD1 RAD52-independent Recombination Mice with DNA Repair Gene (ERCC-1) Deficiency have Elevated Levels of P53, Liver Nuclear Abnormalities and Die Before Weaning Activation of a Recombinase-Deficient Mutant RecA Protein with Alternate Nudenside Triphosphate Cofactors The Kinetics and Mechanism of Repair of UV Induced DNA Damage in Mammalian Cells -the use of Caged Nudeolides and Eleclroporation to Study Short Time Course Events in DNA Repair Evidence for Distinct Primase and Helicase Domains in The 63-kDa Gene-4 Protein of Bacterlophage-T7 -Characterization of a Nucleotide Binding Site Mutant Homologous, Homeologons, and Illegitimate Repair of Double-strand Breaks During Transformation of a Wild-type Strain and a Rad52 Mutant Strain of Saccharomyces Cerevisiae Construction of Chromosomal Rearrangements in Salmonella by Transduction: Inversions of Non-permissive Segments are not Lethal Peptide Nucleic Acid DNA Strand Displacement Loops as Artificial Transcription Promoters Uranyl Photoprobing of a Four-Way DNA Junction -Evidence for Specific Metal Ion Binding Helicase Motifs V and VI of the Escherichia Colt UvrB Protein of the UvrABC Endonoclease are Essential for the Formation of the Preincision Complex Crystal Structure of a Suicidal DNA Repair Protein -the ADA O-6-Methylguanine-DNA Melhyltransferase from E-Coll Effect of Length and Location of Heterologous Sequences on RecAmediated Strand Exchange DNAdependent Protein Kinase is Activated by Nicks and Larger Single-stranded Gaps Triplex-mediated Inhibiliou of HIV DNA Integration in Vitro Purification and Characterization of a Eukaryolic Type-1 Topoisomerase from Pea Chloroplast Rapid Solution Assays for Relroviral Integration Reactions and Their use in Kinetic Analyses of Wild-Type and Mutant Rous Sarcoma Virus Integrases DNA Bending Creates Favored Sites for Retroviral Integration: an Explanation for Preferred Insertion Sties in Nucleosomes The Calf 5'-exonoclease to 3'-exonuclease is Also an Endonuclease with Both Activities Dependent on Primers Annealed Upstream of the Point of Cleavage Structural and Functional Conservation of the Human Homolog of the Schizosaccharemyces Pombe Rad2 Gene, Which is Required for Chromosome Segregation and Recovery from DNA Damage Solution Structure of the DNA Methyl Phosphotriester Repair Domain of Escherlchia-coli Ada Molecular Interactions of DNAtopoisomerase I and II Inhibitor with DNA and Topoisomerases and in Ternary Complexes: Binding Modes and Riological Effects for Intoplicine Derivatives Purification and Characterization of Reverse Gyrase from Sulfolobus Shibalae -Its Proteolytlc Product Appears as an ATP-Independent Topoisomerase DNAprotein Cooperativity in the Assembly and Stabilization of Mu Strand Transfer Complex -Relevance of DNA Phasing and Art Site Cleavage Efficient Copying of Nonhomologous Sequences from Ectoplc Sites Via P-Element-Induced Gap Repair Intramolecular Recombination in Polyomavirus DNA is Controlled by Promoter Elemenls The Purification of a Mismatch-Specific Thymine-DNA Glycusylase from HeLa Cells Efficient Removal of Uracil from G Center Dot U Mispalrs by the Mismatch-Specific Thymine DNA Glycusyiase from HeLa Cells DNA Strand Breaks -the DNA Template Alterations thal Trigger P53-Dependent DNA Damage Response Pathways Characterization of DNA End Joining in a Mammalian Cell Nuclear Extract -Junction Formation is Accompanied by Nucleotide Loss, Which is Limited and Uniform But not Site Specific Landy A: iamlxla Integrase Cleaves DNA in Cis Effect of PH and Temperature on the Stability of UV-induced Repairable Pyrimidine Hydrates in DNA XPG Endonuclease Makes the 3' Incision in Human DNA Nucleotide Excision Repair Isolation of Active Recombinant XPG Protein, a Human DNA Repair Endoouclease Regulation of TFIIH ATPase and • Kinase Activities by TFIIE During Active initiation Complex Formation A V(D)J Recombinase-lnducible B-Cell Line -Role of Transcriplional Enhancer Elements in Directing V(D)I Recombination Production and Characterization of Recombinant Human Ku Antigen Evidence for a coofocmational Change in the DNA Gyrase -DNA Complex from Hydroxyl Radical Foutprinling The Fission Yeast Rad22 Gene, Having a Function in Maliog-Type Switching and Repair of DNA Damages, Encodes a Protein Homolog to Rad52 of Saccharomyces Cerevisiae Interaction of the Yeast RAD7 and SIR3 Proteins: Implications for DNA Repair and Chromafin Structure Cyclin Dl-mediated Inhibition of Repair and Replicative DNA Synthesis in Human Fibrohlasls Identification of the Functional Domains of the FLP Recombinase -Separation of the Nonspeciflc and Specific DNA-Binding, Cleavage, and Ligatlon Domains Interaction of the NH2-and COOH-Terminat Domains of the FIp Recombinase with the FIp Recognition Target Sequence Site-Specific Cleavage and Joining of Single-Stranded DNA by VirD2 Protein of Agrohacterium-tomefacieus Ti Plasmids -Analogy to Bacterial Conjugation Joining Reaction Catalyzed by Relaxase (Tral) of Conjugative Plasmid-RP4 Reconstitution of Mammalian Excision Repair Activity with Mutant Cell-Free Extracts and XPAC and ERCC1 Proteins Expressed in Eschecichiacolt Formation of a ternary Complex by Human XPA, ERCC1, and ERCC4(XPF) Excision Repair Proteins Proximal and Distal Effects of Sequence Contexl on Ultraviolet Mutational Hotspots in a Shultle Vector Replicated in Xeroderma Cells. 1 Mol Bio11994 Hypermutability and Mismatch Repair Deficiency in RER+ Tumor Cells Central Location of the Mu Strong Gyrase Binding Site is Obligatory for Optimal Rates of Replicative Transposition Response of Repaircompetent and Repair-deficient Escherichia Colt to Three O-6-substituted Guanines and Involvement of • Methyl-directed Mismatch Repair in the Processing of O-6-methylguanlne Residues Strand-invasion of Duplex DNA by Peptide Nucleic Acid Oligomers Marians Kh Escherichia-coli Topaisomerase-IV -Purification, Characterization, Subunit Structure, and Subunit Interactions. / Biol (-hem 1993 Quinobenoxazlnes: a Class of Novel Anlilomor Quinolones and Potent Mammalian DNA Topolsomerase II Catalytic Inhibilors Mechanisms of Overlap Formation in Nonhomologous DNA End Joining Illegitimate Recombination Induced by DNA Double-strand Breaks in a Mammalian Chromosome Structure of Four-Way DNA Junctions Containing a Nick in One Strand Induction of Recombination Between Homologous and Diverged DNAs by Double-strand Gaps and Breaks and Role of Mismalch Repair Aberrant DNA Repair and DNA Replication Due to an Inherited Eozymatlc Defect in Human DNA Ligase-I Dual Requirement in Yeast DNA Mismatch Repair for Mlhl and Pros1 Homologs of the Bacterial Mull Gene Liskay RM: MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeasl Human Immunodeficiency Virus Integrase Directs Integration to Sites of Severe DNA Distortion Within the Nucleusome Core Hohn 8: HOU~ologous Recombination in Plant Cells is Enhanced by Invivo Induction of Double Strand Breaks into DNA by a Site-Specific Endonuclease Major Oxidative Products of Cytosine, 5-Hydroxycytosine And 5-Hydroxyuracil, Exhibit Sequence Context-Dependent Mispairing in Vitro• Uracil DNA N-glycosyiase Distributively Interacts with Duplex Polynacleutides Containing Repeating Units of Either TGGCCAAGCU or TGGCCAAGC1TGGCCAAGCU CRE Recombinase-Mediated Site-Speclfic Recombination Between Plant Chromosomes The Saccharomycescerevisiae DNA Repair Gene RAD25 is Required for Transcription by RNA Polymerase-II Zinc-Free and Reduced T4 Gene-32 Protein Binds Single-Stranded DNA Weakly and Fails to Stimulate UvsX-Catalyzed Homologous Pairing Carcinogenesis: Missing Mismatch Repair Sequence-Specific Interactions of UvrABC Endoouclease with Psoralen Interstrand Cross-Links. I Formalion of Base Triplets by Non-Watson-Crick Bonds Mediates Honmlogous Recognition in RecA Recornbinafion Filaments Involvement of the Ku Autoantigen in the Cellular Response to DNA Doublestrand Breaks A DNA End-bindlng Factor Involved in Double-strand Break Repair and V(D)J Recombination Comparative Analysis of Binding of Human Damaged DNA-Binding Protein (XPE) and Escherichia-coli Damage Recognition Protein (UvrA) to the Major Ultraviolet Photoproducts -T Joints Made by RecA Protein in the Interior of Linear Duplex DNA: Effects of Single-stranded Ends, Length of Homology, and Dynamic State Antigen Diversity in the Bacterium B. Hermsii Through "somatic ~ Mutations in Rearranged Vmp Genes Model for a DNA-Mediated Synaptic Complex Suggested by Crystal Packing of Gamma Delta Resolvase Subunits. E/~t80 J 1994 Different Active Sites of Mammalian DNA Ligase-I and Ligase-II. / 8iol Chem Antitomor Bisdioxopiperazines Inhibit Yeast DNA Topoisoraerase II by Trapping the Enzyme in the Form of a Closed Protein Clamp. Pro(-Nail DNA Transport by a Type II DNA Topoisomerase: Evidence in Favor of a Two-gate Mechanism Specificily of Ibe Yeast Rev3 Delta Anfimutator and REV3 Dependency of the Mutator Resulting from a Defect (radt Delta) in Nucleotide Excision Repair The Beta Recombinase from the Streptococcal Plasmid PSM19035 Represses its Own Transcription by Holding the RNA Polymerase at the Promoter Region A Novel Site-Specific Recombinase Encoded by the Streptococcus Pyogenes Plasmid Psmtg035 Characterizaliun of Broken DNA Molecules Associated with V(D)J Recombination Expression of a Site-specific Endouuclease Stimulates Homologous Recombination in Mammalian Celk The MO15 Cell Cycle Kinase is Associated with the TFIIH Traoscription-DNA Repair Factor Structure of REC2, a Recombinational Repair Gene of Ustilago Maydis, and Its Function in Homologous Recombination Between Plasmid and Chrornnsomal Sequences Idenfificatioo of a Mutanl Human Topols~neraseol with Intact Catalytic Activity and Resistance TO 9-nitro-camptothecin Definition of a Cote Region of RAG-2 that is Functional in V(D) Expression and V(D) Single Strand and Double Strand DNA Damage-induced Reciprocal Recombination in Yeast. Dependence on Nucleotide Excision Repair and RAD1 Recombination Production of UV-ioduced Frameshift Mutations in Vitro by DNA Polymerases Deficient in 3'--~5' Exouuclease Activity Homology-associated Nonhomologoos Recombination in Mammalian Gene Targeting Cloning and Expression of CDNA for a Human Enzyme that Hydrolyzes 8-oxo-dGTP, a Mutagenic Subslrate for DNA Synthesis Use of High and Low Level Overexpression PJasmids to Test Mutant Alleles of the RecF Gene of Eschericbia Coli K-12 for Partial Activity Repair of Triple Helix Directed Psoraleo Adducts in Human Cells Dual Function for Poly(ADP-ribuse) Synthesis in Response to DNA Strand Breakage Base Selection, Proofreading, and Mismatch Repair During DNA Repllcatloo in Escherlchia-coli The ERCC2/DNA Repair Protein is Associated with the Class II BTF2/TFIIH Trauscripfion Factor. EMBO I DNA Repair Helicase: a Componenl of BTF2 (TFIIH) Basic Transcription Factor Homology Dependence of Targeted Recombination at the Chinese Hamster APRT LOCus Effect of Mutations in Genes Affecting Homologous Recombinafion on Restriction Enzyme-mediated and IIIngitimate Recombination in Saccharomyces Cerevisiae Epigenetic Regulation of the Maize Spin Trauspusable Element -Novel Activation of a Methylated Promoter by Tnpa Pens A: Double-Strand Signal Sequence Breaks in V(D)J Recombination are Blunt, 5'-Phosphorylaled, RAG-Dependent, and Cell Cycle Regulated Intramolecular and intermolecular DNA Ligation Mediated by Topolsomera~e II Identification of Joiut Molecules thai Form Frequenlly Between Homolog~ But Rarely Belween Sister Chrornatids During Yeast Meiosis Synaptlc Inlermediates in Bacteriophage tambda Site-Specific Recombination -Integrase can Align Pairs of Attachment Sites Approaches to Half-Tetrad Analysis in Bacteria -Recombination Between Repeated, Inverse-Order Chromosomal Sequences Molecular Mechanism of ee Transcription-repair Coupling Service R: Cancer Research -Slow DNA Repair Implicated in Mutations Found in Tumors Recombination in B-Cells is Impaired But not Blocked by Targeted Deletion of the Immunoglobolin Heavy Chain Intron Enhancer Activalion of RuvC Holliday Junction Resolvase in Vitro Stimulation of Kappa Light-Chain Gene Rearrangement by Ihe Immunnglobulin Mu Heavy Chain in a Pre-B-Cell Line Mitochoodrlal Topoisomerase II Acfivity is Essential for Kinetoplast DNA Minicircle Segregation Vivo Inhibition of Trypanusome Milochondrial Topolsomerase Ih Effects on Kinetoplasl DNA Maxicircles Efficient Homologous Recombination of Ty1 Element CDNA when Inlegrafion is Blocked A Mutation in Helicase Motif III of E-Coil Recg Protein Abolishes Branch Migration of Holliday Jundlons Cloning of Human, Mouse and Fission Yeast Recombination Genes Homologous to RAD5t and RecA Plasmid-Mediated Induction of Recombination in Yeast Dispensable Sequence Motifs in the RAG-1 and RAG-2 Genes for PlasmidW(D)l Recombination Functionally Important Residues at a Subonlt Interface Site in Ihe RecA Protein from Escherichia-coli Purification and Characterization of DNA Topolsomerase-V -an Enzyme from the Hyperthermophilic Prokaryote Methanopyruskandleri that Resembles Eukaryotic Topoisomerase-I Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku CDNA Structure of the P22 Att Site -Conservation and Divergence in the Lambda Motif of Recombinngenic Complexes Deletion Mutants of Poly(ADP-ribose) Polymerase Support a Model of Cyclic Association and Dissociation of Enzyme from DNA Ends During DNA Repair An Env-like Protein Encoded by a Drosophila Retroelemenl: Evidence Ihat Gypsy is an Infectious Retroviru~ Fuses the Ews Gene to Another ETS-Family Transcription Factor, ERG Computer Models of DNA Fonr-way Junctions Further Tests of a Recombination Model in Which Cbi Removes the Recd Subunit from the RecBCD Enzyme of Escherichia Coil Generation of Temperature-Sensitive Cbpl Strains of Saccharomyces Cerevisiae by PCR Mutagenesis and in Vivo Recombination -Characteristics of the Mutant Strains Imply that Cbpl is Involved in Stabilization and Processing of Cytochrome B Pre-Mrna The Linkage Change of a Knotting Reaction CataJysed by Tn3 Resolvase The Escherichia Coil RuvB Branch Migration Protein Forms D~Jble Hexamerlc Rings Around DNA Vaccinia DNA Topoisomeraso-I -Single-Turnover and Steady-State Kinetic Analysis of the DNA Strand Cleavage and Ligatlon Reactions Introduction of a Tryptophan Reporter Group into Loop 1 of the RecA Protein -Examination of the Conformational States of the RecA*Ssdna Complex by Fluorescence Spectroscopy Destabilizalion of Tracts of Simple Repetitive DNA in Yeast by Mutations Affecting DNA Mismatch Repair DNA Repair -the Nick in Time Autnantigenic Proteins that Bind Recombinogenic Sequences in Epstein-Barr Virus and Cellular DNA Catalysis of ATP-dependeut Homologo~ DNA Pairing and Strand Exchange by Yeast RAD51 Protein. Science Negative Superhelicity Promotes ATP-Dependenl Binding of Yeast Rad3 Protein to Ultraviolet-Damaged DNA UV Damage to DNA Strongly influences Its Rotational Setting on the Hisloue Surface of Reconstituted Nuclensomes Complex) Assembles on Double-stranded DNA The COOH Terminus of Suppressor of Stern Loop (SSL2/RAD25) in Yeast is Essential for Overall Genomic Excision Repair and Transcrlption-Coupled Repair Inlrachromusomal Homologoos Recombination in Whole Plants Crossover Interference is Abolished in the Absence of a A DNA Repair Defect in Chinese Hamster Ovary Cells Affects V(D)I Recombination Similarly to the Muriue Acid Mutation KU80: Product of the XRCC5 Gene and Its Role in DNA Repair and VID)J Recombination Structural Requirements of Subslrate DNA for Binding to and Cleavage by RuvC, a Holliday Junction Resolvase Intragenic Recombination at the Human Phusphnglucomutase-1 Locus -Predictions Fulfilled Deletion of the Immunoglobulin Kappa-Chain Intron Enhancer Abolishes Kappa-Chain Gene Rearrangemenl in Cis But not Lambda-Chain Geue Rearrangement in Trans Repair of Benzo(A)Pyrene Diol Epoxide-and UV-Induced DNA Damage in Dihydrofolate Reductase and Adenine Phosphorlbosyltransferase Genes of CHO Cells Formation and Repair of Antltumor Antibiotic CC-1065-1nduced DNA Adducts in the Adenine Phosphoribosyllransferase and Amplified Dihydrofolate Redoctase Genes of Chinese Hamster Ovary Cells Cloning of Chinese Hamster DNA Topoisomerase-I CDNA and Identification of a Single Point Mutation Responsible for Camptothecin Resistance Induction of Cleavage in Topoi$omerase-I C-DNA by Topoi~nlera~-I Enzymes from Calf Thymus and Wheal Germ in lhe Presence and Absence of Camptuthecin Substrale Specificity of Fpg Protein -Recognition and Cleavage of Oxidatively Damaged DNA Waldman AS: The Search for Homology Does not Limit the Rate of Extrachromoson~l HOmologOUS Recombination in Mammalian Cells A Mutational Study of the C-Terminal Zinc-Finger Motif of the Escherichia Colt Uvra Protein. l BiD/Chem Crucial Role for DNA Supercoiling in Mu Transposition -a Kinetic Study Transcription Factor B (Tfiih) is Required During Nucleotide-Excision Repair in YeasL Nature Mechanistic Studies of Amsacrine-resistant Derivatives of DNA Topoisomerase II -Implications in Resistance to Multiple Antitumor Drugs Targeting the Enzyme The Saccharomyces-cerevisiae DNA Repair Gene RAD23 Encodes a Nuclear Protein Containing a Ubiquitin-Like Domain Required for Biological Function Mitotic Checkpoln! Genes in Budding Yeast and the Dependence of Mitosis on DNA Replication and Repair A Functional Analysis of the Tn5 Transposase -Identification of Domains Required for DNA Binding and Multimerizalion Adeno-assnciated Virtu (AAV) Rep Proteins Mediate Complex Formation Between AAV DNA and Its Integration Site in Human DNA Free Radical Adducts Induce Alterations in DNA Cytosine Methylation Small Family of Elements with Long Inverled Repeats is Located Near Sites of Developmentally Regulated DNA Rearrangement in Tetrahymena Thermophila The Processing of Recombination Intermediates -Mechanistic Insights from Studies of Bacterial Proteios Reverse Branch Migration of Holliday Junctions by RecG Protein -a New Mechanism for Resolution of Intermediates in Recombination and DNA Repair Ioteraction of To5 Transposase with the Transposon Termini Interactions Between DNA Molecules Bound to RecA Filament -Effects of Base Complementarity Mismatch Repair Proteins MuIS and MulL Inhibit RecA-Catalyzed Strand Transfer Between Diverged DNAs Double Replacement -Strategy for Efficient Introduction of Subtle Mutations into the Murine Colla,1 Gene by Homologous Recombination in Embryonic Stem Cells Molecular Cloning of a Zinc Finger Protein Which Binds to the Heptamer of Ihe Signal Sequence for V(D)J Recombination Meiosis-Induced Double-Strand Break Sites Determined by Yeast Chromatin Structure Cyto~ne Deaminalions Catalyzed by DNA Cytosine Methyltraosferases are Unlikely to be the Major Cause of Mutalional Hot Spots at Sites of Cytosine Methylation in Escherichia Coll The Redox and DNA-Repair Activities of Ref-1 are Encoded by Nonoverlapping Domains Different Capacities for Recombination in Closely Related Human Lymphoblaslold Cell Eines with Different Mutational Responses to X-irradiation A Common Elemenl Involved in Transcriptional Regulation of Two DNA Alkylation Repair Genes (MAG and MGT1) of Saccharomyces-cerevisiae Generality of the Shared Active Site Among Yeast Family Site-Specific Recombinasesthe ARG Site-Specific Recombinase Follows the FIp Paradigm Generality of the Shared Active Site Among Yeast Family Site-specific Recombinases. The R Site-specific Recombinase Follows the FIp Paradigm Mammalian Topolsomerase I Has Base Mismatch Nicking Activity Repair of O6-methylguanine and O4-methylthymine by the Human and Rat O6-methylguanine-DNA Methyltraosferases DNA Polymerase Delta is Involved in the Cellular Respon~ to UV Damage in Human Celk The CarboxyI-Terminal Residues of Escherichia Colt DNA Topoisomerase III are Involved in Substrale Binding A Selective Defect in IgG2b Switching as a Result of Targeled Mutation of the I-gamma-2b Promoter and Exon Symmetric Holliday Junction Crossover Isomers Effect of DNA Cytosine Methylation Upon Deamination-lnduced Mutagene~s in a Natural Target Sequence in Duplex DNA An Inhibitor of DNA Tol~Oisomerase~l from Xenopus-laevis Ovaries Evolution of Recombination Among Multiple Selected Loci -a Generalized Reduction Priociple DUN1 Encodes a Protein Kinase that Controls the DNA Damage Response in Yeast A Parallel DNA Tripler as a Model for the Intermediate in Homologous Recombination Analysis of Two Distinct Single-Stranded DNA Binding Sites on the RecA Nucleoprotein Filament Struclural Requirements of 55 RRNA for Nuclear Transport, 75 Ribonucleoprotein Particle Assembly, And 60s Ribosomal Suhonit Assembly in Xeonpus Oocytes Ehresmann 8, Ehresmann C: Role of Conserved Nuclentides in Building Ibe 165 RRNA Binding Site of E.coli Ribosomal Prolein $8 beta-casein MRNA Sequesters a Single-stranded Nucleic Acid-binding Protein Which Negatively Regulates Ibe Beta-casein Gene Promoler A Novel Transforming Growth Faclor-beta(1) Responsive Cytoplasmic Trans-Acting Factor Binds Selectively Io the 3'-untranslated Region of Mammalian Rihonucleolide Reductase-R2 Messenger RNA -Role in Me'~age Stability Phorbol Ester Modulation of a Novel Cytoplasmic Protein Binding Activity at the 3'-Untranslated Region of Mammalian Rihonudeotide Reductase R2 Mrna and Role in Message Stability Editing Does not Exist for Mammalian Selenocysteine Transfer RNAs Stohzfus CM: Presence of Negative and Positive Cis-acting RNA Splicing Elements Within and Flanking the First Tat Coding Exou of Human Immunodeficiency Virus Type 1 The Role of Specific Protein-RNA and Proteil~Protein tnlneractioos in Pusilive and Negative Control of Pre-mRNA Splicing by Transfocmer2 Mutagenesis of the Hairpin Ribozyme Cloning and Functional Analysis of Spliced Isoforms of Human Nuclear Factor I-X. Interference with Transcriptional Activation by NFUCTF in a cell-type Specific Manner Enhanced Translational Efficiency of a Novel Transforming Growth Factorbeta-3 Messenger RNA in Human Breast Cancer Cells FMR1 Protein -Conserved RNP Family Domains and Selective RNA Binding Multiple Messenger RNA tsoforms Encoding the Mouse Cardiac Kvl-5 Delayed Rectifier K+ Channel Verlebrale MRNAS with a 5'-terminal Pyrlmidine Tract are Candidates for Translational Relx'e~ion in Quiescent Cells: Characterization of the Translational Cis-regulalory TRAP, the Trp RNA-binding Atlen~alion Protein of Bacillus Subtilis, is a Multlsuhonit Complex 1hat Appears to Recognize G/UAG Repeats in 1he TrpEDCFBA and TrpG Transcripts Two Forms of Phospholipase C-beta 1 Generated by Alternative Splicing Developmental Characlerization of a Drosophila RNA-blnding Protein Homologous to the Human Syslemic Lupus Erythematns~-assnciated La/SS-B Autoantigen Identification of a Novel HIV-1 TAR RNA Bulge Binding Proleln Fournier Mk Saccharomyces-cerevisiae U14 Small Nuclear RNA Has Liffie Secondary Structure and Appears to be Produced by Post-Traoscripilonal Processing snR31, SnR32, and SnR33 -Three Novel, Non-Essential SnRNAs from Saccharomyces-cerevisiae Splicing of the Allemative £xons of the Chicken, Rat, and Xeonpus Beta Tropemyosin Transcripts Requires Class-specific Elements A Nuclear Mutation in Maize Blocks the Processing and Translation of Several Chloroplasl MRNAs and Provides Evidence for the Differential Translation of Alternative MRNA Forms Roos Sarcoma Virus RNA Stability Requires an Open Reading Frame in the GAG Gene and Sequences Downslream of Ihe GAG-POt Junction Tissue-Specific Alternative Splicing Generates 2 Isuforms of the TrkA Receptor Eukaryotic Selenncysteine Inserting TRNA Species Support Selenoproteln Synthesis in Escherichia Coll The Iron-Responsive Element-Binding Protein -Localization of the RNA-Binding Site to the Aconitase Active-Site Cleft Polyadenylalion and Transcription Termination in Gene Constructs Containing Multiple Tandem Polyadenylallon Signals Structure of Influenza Virus RNP. I. Influenza Virus Nucleoprotein Melts Secondary Struclure in Panhandle RNA and Exposes the Bases Io the Solvent Splicing of Balbiani Ring A Kinetic Mechanism for Cleavage of Precursor TRNA(Asp) Catalyzed by the RNA Component of Bacillus Subtilis Ribonnclease P Differential Effects of Translational Inhibition in Cis and in Trams on the Decay of the Unstable Yeast MFA2 Messenger RNA Genetic and • Physical Interactions Between Srplp and the Nuclear Pore Complex Proteins Nuplp and Nup 2p Nonsense But not Mis~eose Mutations can Decrease the Abundance of Nuclear MRNA for the Mouse Major Urinary Protein, While Both Types of Mutations can Facilitate Exon Skipping Production and Cleavage of Drosophila Hsp70 Transcripts Extending Beyond Ibe Polyadenylation Site Synlhelic Lelhalily wilh Fibrillarin Identifies NOP77p, a nucleolar Protein Required for Pre-rRNA Processing and Modification Effect of Acidic Ribosomal Phosphoprotein Mrna 5'-Untranslated Region on Gene Expression and Protein Accumulation The Human Messenger RNA Encoding the Goodpasture Antigen is Allernalively Spliced Selenocysteine Insertion or Termination: Factors Affecting UGA Codon Fate and Complementary Ant.cudon:codon Mutations Fluorescence-detected Stopped Flow with a Pyreue Labeled Substrate Reveals that Guanusine Facilitates Docking of the 5' Cleavage Site into a High Free Energy Binding Mode in the Tetrahymena Ribuzyme Nuclear Polyadenylalion Factors Recognize Cyloplasmic Polyadenylation Elements Mutations in 23-S Ribosomal RNA Perturb Transfer RNA Selection and can Lead to Streptomycin Dependence Evidence thai the Pathway of Transferrin Receptor Mrna Degradation Involves an Endonocleolytic Cleavage Within the 3' UIr and Does not Involve Poly(A) Tail Shortening Self-splicing Group I Intron in Cyanohacterial Initiator Methionine TRNA: Evidence for Lateral Transfer of Introns in Bacteria Analysis of Ibe RNA-Recognition Motif and RS and Rgg Domains -Conservation in Metazoan Pre-Mrna Splicing Factors Introduction of a Heterologous Editing Site into the Tobacco t~astid Genome: the Lack of RNA Editing Leads to a Mutant Pbenotype Positions +5 And +6 can be Major Delerminants of the Efficiency of Non-AUG Initiation Codons for Protein Synthesis • nup 1 Mutants Exhibil Pleiotrophic Defects in Nuclear Pore Complex Function Characterization and Partial Purification of MRNA N-6-adenosine Methyltraosferase from HeLa Cell Nuclei .Internal MRNA Methylation Requires a Multisubunil Complex. I 8iol Chem Ah Evolutionary Conservation of the Structure and Expression of Alternatively Spliced Ultrabithorax Isoforms from Drosophila The Deadenylation Conferred by the 3' Unlranslated Region of a Developmentally Controlled Mrna in Xenopus Embryos is Switched to Polyadenylation by Deletion of a Short Sequence Element A Role for Transcripllon and FRGY2 in Masking Maternal MRNA Within Xenopns Oocytes Alternative Splicing Generates Multiple Isoforms of a Rabbit Prostaglandin E(2) Receptor A Cis-acting Repressive Sequence that Overlaps the Rev-responsive Element of Human Immunodeflciency Virus Type 1 Regulates Nuclear Retention of Env MRNAs Independently of Known Splice Signals Specialized Ribosomes Allow for the Study of Mutations in Functionally Important Regions in 16-S RRNA, Without Affecting Cell Growth -the Identification of Functional Regions in the Central Domain of 16-S RRNA Interactions Among Three Proteins that Specifically Activate Translation of Ihe Mitochondrial COX3 MRNA in Saccharomyces Cerevisiae Invitro Genetic Analysis of the Structural Features of Ihe Pre-Traosfer RNA Required for Determination of the 3' Splice Site in the Intron Excision Reaction RNA Binding Specificity of Hnrnp A1 -Significance of Hnrnp A1 High-Affinity Binding Sites in Pre-Mrna Splicing Conserved Structures and Diversity of Functions of RNA-binding Proteins Functional Analysis of Pre-Messenger RNA Splicing Factor SF2/ASF Slructural Domains Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors Vitro Study of Processing of the Intron-Encoded U16 Transferrin Receptor Gene Expression During Rat Liver Regeneration -Evidence for PosI-Traoscriptional Regulation by Iron Regulatory Factor(B), a Second Iron-Responsive Element-Binding Protein Ribozyme Cleaves Rex/tax Messenger RNA and Inhibits Bovine Leukemia Virus Expression A Novel Bipartite Splicing Enhancer Modulates the Differential Processing of the Human Fibroneciin EDA Exon Copurification of E-Coil Rnaase E and Pnpase -Evidence for a Specific Association Between Two Enzymes Important in RNA Processing and Degradation Imprecise Excision of the Caenorhabditis Elegans Transposon Tcl Creates Functional 5' Splice Sites RNA -Life after Transcription Induction of RNA-Binding Proteins in Mammalian Cells by DNA-Damaging Agents Characterization and Cloning of the Human Splicing Factor 9G8: a Novel 35 KDa Factor of the Serine/Arginine Protein Family Pokeweed Antiviral Protein (PAP) Mutations Which Permit E.coli Growth do not Eliminate Catalytic Activity Towards Prokaryollc Ribosomes The Prespliconsome Components SAP 49 and SAP 145 Interact in a Complex Implicated in Tethering U2 SnRNP to the Branch Site A Novel Mechanism of Ha-Ras Oncogene Action -Regulation of Fibronectin Mrna Levels by a Nuclear Posttranscriptional Event Interaction of Intronic Boundaries is Required for the Second Splicing Step Efficiency of a Group-II Intron Interaction Between the First and Last Nucleotides of Pre-mRNA Introos is a Determinant of 3' Splice Site Selection in S-cerevisiae Tinoco h Nucleoside Triples from the Group-I Intron Purification and Characterization of Bacterially Expres~d Mammalian Translation Initiation Factor 5 (elf-5) -Demonstration that Elf-5 Forms a Specific Complex with Elf-2 ATF3 and ATF3 Della Zip -Transcriptional Repression Versus Activation by Alternatively Spliced Isoforms Interplay Of 2 Functionally and Structurally Distinct Domains of the C-Fns Au-Rich Element Specifies Its Mrna-Destabilizing Function Effect of the Relative Position of the UGA Cndon Io the Unique Secondary Structure in the FdhF Messenger RNA on Its Decoding by Seienocysteinyl Transfer RNA in Escherichia-coli The Influence of Adenine-rich Motifs in the 3' Portion of the Ribnsume Binding Site on Human IFN-gamma Gene Expression in Escherichla Coll Large Exon Size Does not Limit Splicing in Vivo Cyclic AMP Selectively Increases Renin Messenger RNA Stability in Cultured )uxtagiomerular Granular Cells Hepatic Polysomes thai Contain Apoprotein-B Messenger RNA have Unusual Physical Propeclies Introns are Cis Effectors of the Nonsense-codon-mediated Reduction in Nuclear MRNA Abundance Formation of the Yeast Splicing Complex A1 and Association of the Splicing Factor PRP19 with the Pre-mRNA are Indepandent of the 3' Region of the lutron Specific Protein-protein Interactions Between the Essential Mammalian Splicensomeassociated Proteins SAP 61 and SAP 114 Tumor Necrosis Factor Induces a Block in Ihe Cotranslalion of Fc Gamma RIIb MRNA in Mouse Peritoneal Macrophages Expression of Human Apolipoprotein B100 in Transgenic Mice -Editing of Human Apolipoprotein-B100 Messenger RNA Sequence and Position Requirements for Uridylale-rich Downstream Elements of Polyadenylalion Signals Identification of a Thymidylate Synthase Ribunucleoprotein Complex in Human Colon Cancer Cells The Effect of Reducing Reagents on Binding of Thymidylate Synthase Protein to Thymidylate Synthase Messenger RNA The RNA of RNase MRP is Required for Normal Processing of Ribosomal RNA. Proc Natl Acad 5ci U 5 A The Human DNA Polymerase Beta Gene Structure. Evidence of Alternative Splicing in Gene Expression A Nuclear Function for RNase MRP. Proc Nail Acad 5ci U S A Escherichia Colt Proteins, including Ribosomal Protein S12, Facilitate in Vitro Splicing of Phage T4 Introns by Actiog as RNA Chaperones RNAs with Dual Specificity and Dual RNAs with Similar Specificity A Group III Twintron Encoding a Maturase-Like Gene Excises Through Lariat Intermediates Mutations in the Conserved Loop of Human U5 SnRNA Generate use of Novel Cryptic 5' Splice Sites Invivo RAG-1 Interacts with the Repeated Amino Acid Motif of the Human Homologue of the Yeast Protein SRP1 Neural Expression of a Novel Alternatively Spliced and Polyadenylated Gs-alpha Transcript Inhibition of HIV-1 Replication by Ribozymes that Show Poor Activity Invitro Complementation by SR Proteins of Pre-mRNA Splicing Reactions Depleled of U1 SnRNP Structure of a Mispaired RNA Double Helix at 1.6-A Resolution and Implications for the Prediction of RNA Secondary Structure Binding of Encephalumyocarditis Virus RNA Polymerase to the 3'-noncoding Region of the Viral RNA is Specific and Requires the 3'-poly(A) Tail Hypoxia Stimulates Binding of a Cytoplasmic Protein to a Pyrimidine-Rich Sequence in the 3'-Untranslated Region of Rat Tyrosine Hydroxylase Messenger RNA A Comparative Database of Group I Introu Slrnctores ADP-dependent Phnsphorylation Regulates RNA-binding in Vitro: Implications in Lightmodulated Translation Enhanced Activation of the Human Histone H2B Promoter by an Oct-1 Variant Generated by Alternative Splicing RNA Trans-splicing in Fasciola Hepatica -Identification of a Spliced Leader (SL) RNA and SL Seq~uences on MRNAS Database on the Structure of Large Ribosomal Sul~nil RNA Mutations in lhe Gcd7 Subunit of Yeast Guanine Nucleotide Exchange Factor EIF-2B Overcome the Inhibitory Effects of Phosphorylated Elf-2 on Translation Initiation Identification of Plant Genetic Loci Involved in a Posttranscriptional Mechanism for Meiotically Reversible Transgene Silencing Identification, Molecular Cloning, Expression and Chromosome Mapping of a Family of Transformation Upregulated Hnrnp-K Proteins Derived by Alternative Splicing A Segment of Messenger RNA Encoding the Leader Peplide of the CPA1 Gene Confers Repression by Ar~inine on a Heterologous Yeast Gene Transcript Preferential Deadenylation of Hsp7O MRNA Plays a Key Role in Regulating HspT0 Expression in Drosophila Melanogastec Control of Nucleo-cytopla~rnic NLA-DRA MRNA Partitioning by Interaction of a Retention Signal with Compartmentalized Proteins Conservation of Regulated Alternative Splicing and Identification of Functional Domains in Vertebrate Homologs to the Drosophila Splicing Regulator, Suppressor-of-white-apricot Ribozyme Mediated Degradation of Beta-amyloid Peplide Precursor MRNA in COS-7 Cells Probing Structural Differences Between Native and Invitro Transcribed Escherichiacolt Valine Transfer RNA -Evidence for Stable Base Modification-Dependeut Conformers Translational Initiation on Structured Messengers -Another Role for the Shine-Dalgarno Interaction Translational Maintenance of Frame -Mutants of Saccharomyces Cerevisiae with Altered -1 Rib~l Frameshiffing Efficlencies A Porine-Rich Exon Sequence Enhances Alternative Splicing of Bovine Growth Hormone Pre-Mrna Eight Genes and Alternative RNA Processing Pathways Generate an Unexpectedly Large Diversily of Cytoplasmic Intermediate Filamenl Proteins in the Nematode Caenorhabdltis Elegans The Sequences of Human and Bovine Genes of the Phosphate Carrier from Mitochondria Contain Evidence of Alternatively Spliced Forms A Tertiary Interaction in the Tetrahymena Inlron Contributes to Selection of The 5' Splice Site A Novel Nuclear Pore Protein • o Nup 133p with Distinct Roles in Poly (A) + RNA Transport and Nuclear Pore Distribution Induction of RNA Ediling at Heterolngous Sites by Sequences in Apolipoprotein-B Messenger RNA Expression and Characterization of P27, the Catalytic Subuoit of the Apolipoproteln B MRNA Editing Enzyme Orientations of Transfer RNA in the Ribosomal a and P sites Ribozyme-Medialed Attenuation of Pancreatic Beta-Cell Glucokinase Expression in Trausgenic Mice Results in Impaired Glucose-Induced Insulin Secretion Selection of a Preribosomal RNA Processing Site by a Nocleolar Endoribonuclease Involves Formation of a Stable Complex Inhibition of Protein Synthesis by an Efficiently Expressed Mutation in the Yeast 5.85 Ribosomal RNA Design and Specificity of Hammerhead Ribozymes Against Calretinin Messenger RNA Yeast Mitochondrial NAD+-Dependent Isocitrate Dehydrogenase is an RNA-Binding Protein Self-Splicing of the Tetrahymena Pre-rRNA is Decreased by Misfolding During Transcription Fingerprinting the Folding of a Group I Precursor RNA Exclusion of an Alternatively Spliced Exou in Human ATP Synthase Gamma-Subunil Pre-Mrna Requires De Novo Prolein Synthesis Determination of Messenger RNA Fate by Different RNA Polymerase-II Promoters The Ca2+ Affinity of the Plasma Membrane Ca2+ Pump is Controlled by Alternative Splicing Two Independent and Interactive DNA-binding Subdomaius of the Pax6 Paired Domain are Regulated by Alternative Splicing Similar Alternative Splicing Events Generate 2 Sarcoplasmic of Endoptasmic Reticulum CA-ATPase Isoforms in the Crustacean Arlemia-Franciscana and in Vertebrates An Active Recombinant P15 RNase H Domain is Functionally Distinct from the RNase H Domain Associated with Human Immunodeficiency Virus Type 1 Reverse Traoscriptase Translational Control of Maternal GIp-1 MRNA Establishes an Asymmetry in the C. Elegans Embryo Hurt EC: • * Nup 145p is Required for Nuclear Export of MRNA and Binds Homopolymeric RNA in Vitro via a Novel Conserved Motif L0hrmann R: Isolation of S. Cerevisiae SoRNPs: Comparison of U1 and U4/U6.U5 to Their Human Counterparts Purification of Two Isoforms of HnRNP-U and Characterization of Their Nucleic Acid Binding Activity Premature Translation Termination Mutations are Efficiently SuppreoAed in a Highly Conserved Region of Yeast Ste6p, a Member of the ATP-binding Cassette (ABC) Transporter Family Casein Kinase II Mediates Multiple Phosphorylalion of Saccharomyces Cerevisiae ELF-2 AIl~aa (encoded by SUI2), Which is Required for Optimal ELF-2 Function in S.cerevisiae Alternative Splicing of the NC1 Domain of the Human-alpha 3(IV) Collagen Gene -Differential Expression of Messenger RNA Trauscripts that Predict Three Prolein Variants with Distinct Carhoxyl Regions • Nuclear Transport of U1 SnRNP$ in Somatic Cells: Differences in Signal Requirements Compared with Xenopus taevis oocytes Evidence Ihal HIV-1 Rev Directly Promotes the Nuclear Export of Uospliced RNA A Yeast RNA-binding Protein Shuttles Between the Nucleus and the Cytoplasm The Drosophila Sex Determination Gene Snf Encodes a Nuclear Protein with Sequence and Functional Similarity to Ihe Mammalian U 1A SnRNP Protein Crystal Stroclure of Ribonuclease a Center Dot D(ApTpApApG) Complex -Direct Evidence for Extended Substrale Recognition Discrimination Between Initiation and Elongation of Protein Biosynthesis in Yeast -Identity As'JJred by a Nucleofide Modification in the Initiator Transfer RNA Effector Region of the Translation Elongation Factor EF-Tu GTP Complex Stabilizes an Orthoester Acid Intermediate Structure of Aminoacyl-tRNA in a Ternary Complex Influenza Virus NS1 Protein • Inhibits Pre-mRNA Splicing and Blocks MRNA Nucleocytoplasmlc Transport A Stem/Loop in U6 RNA Defines a Conformational Switch Required for ere-Messenger RNA Splicing Recognition and Cleavage of Hairpin Structures in Nucleic Acids by Oligodeoxynocleotldes Rational Design of Selfcleaving Pre-IRNA Ribonuclease P RNA Conjugates Architecture of the U5 Small Noclear RNA Thermal Activation of a Group II Intron Ribozyme Reveals Multiple Conformational States Active Site of the MRNA-capping Enzyme Guanylyltransferase from Saccharomyces Cerevisiae: Similarity to the Nucleotidyl Attachment Motif of DNA and RNA Ligases Evidence for a Role of the D rusophila-Melanogaster-Suppressor -of-Sable Gene in the Pre-Messenger RNA Splicing Pathway Importance of Specific Guanosine N7-Nitrogens and Purine Amino Gronps for Efficient Cleavage by a Hammerhead Ribozyme Gorski h High Affinity Binding of the Estrogen Receptor to a DNA Response Element Does not Require Homodimer Formation or Estrogen Sequences Homologous to S' Splice Sites are Required for the Inhibitory Activity of Papillomaviru: Late 3' Untranslated Regions Poly(A) Binds to Initiation Factors and Increases Cap-dependent Translation in Vitro Structural Study of the S' End of a Synthetic Premessenger RNA from Adenovirus -Evidence for a Long-range Exon-intron Interaction Translational Control by Influenza Virus -Selective Translation is Mediated by Sequences Within Ihe Viral Messenger RNA S'-Untrauslated Region Post-Transcriptional Regulation of Interleukin 1 Alpha in Various Strains of Young and Senescent Human Umbilical Vein Endothelial Cells Mutations in the Gene for a TRNA that Functions as a Regulator of a Transcriptional Attenuator in Bacillus Subtilis Translation Initiation Factor-elF-2 -Cloning and Expression of the Human CDNA Encoding the Gamma-Subunit Interhelix Geometry of Stems I and II of a Self-Cleaving Hammerhead RNA Discovery of Group I Introns in the Nuclear Small Subunit Ribosomal RNA Gelds of Acanthamoeha Translational Regulation of Nanos by RNA Localization Overexpression and Purification of the Soluble Polyhydroxyalkanoate Synlhase from Alcaligenes Eutrophus: Evidence for a Required Pnsttranslalional Modification for Catalytic Activity Uridylate-Containing RNA Sequences Determine Specificity for Binding and Polyadenylalion by the Catalytic Subunit of Vaccinia Virus POly(A) Polymerase Interaction of Small Ribosonlal and Transfer RNAs with a Protein from Leishmania Donovanl Characterization of Transcription Initiation, Translation Initiation, and POly(A) Addition Sites in the Gene-Sized Macronuclear DNA Molecules of Euplotes Detection of DsRNA-binding Domains in RNA Heticase a and Drosophila Maleless: Implications for Monomeric RNA Helicases Lapeyre 8: Identification of a Segment of the Small Nucleolar Ribonucleoprotein-associated Protein GAR1 that is Sufficient for Nucleolar Accumulation Thermodynamics of Folding a Pseudoknotted MRNA Fragment Short Artificial Hairpins Sequester Splicing Signals and Inhibit Yeast ere-Messenger RNA Splicing GTPase Cycle for Nuclear Transport Mutation of an RSV Intronic Element Abolishes Both U11/U 12 SnRNP Binding and Negative Regulation of Splicing Tetrahymena Ribozyme Disrupts RRNA Processing in Yeast The Formation of Mitochondrial Ribonucleoprotein Complexes Involving Guide RNA Molecules in Trypanosoma Brucei Degradation of Unstable Interleukln-1 Alpha Mrna in a Rabbit Reticulocyte Cell-Free System -Localization of an Instability Determinant to a Cluster of Auuua Motifs Substitutional and Insertional RNA Editing of the Cytochrome-c Oxidase Subunit-1 Messenger RNA of Physarumpolycephalum. I Biol Evidence that Alternate Foldings of the Hepatitis Delta RNA Confer Varying Rates of Self-Cleavage A Novel Set of Splicesomeassociated Proteins and the Essential Splicing Factor PSF Bind Stably to Pre-mRNA Prior to Catalytic Step II of the Splicing Reaction Cross-Linking of Messenger RNA Analogues Containing 4-Thiouridine Residues on the 3'-Side or 5'-Side of the Coding Triplet to the Messenger RNA Binding Center of the Human Ribosome The Nucleic Acld-binding Zinc Finger Protein of Potato Virus M is Translated by Internal Initiation as Well as by Ribosomal Frameshifting Involving a Shifty Slop Codon and a Novel Mechanism of P-site Slippage Effect of Sequence Context at Stop Codous on Efficiency of Reinitiation in Gcn4 Translational Control Requirements for Intercislronic Distance and Level of Eukaryotic Initiation Factor-2 Activity in Reinitiation on GCN4 Messenger RNA Vary with the Downstream Cistron RNA -Pan-Editlng in the Beginning Invitro Genetic Analysis of the Hinge Region Between Helical Elements PS-P4-P6 and Elements P7-P3-P8 in the SunY Group-I Self-Sphcing Iotron Mutations in the Peptidyl Traosferase Region of E-Coil 235 RRNA Affecting Translalional Accuracy Translation of Nad9 MRNAs in Mitochondria from Solanum Tol~rosum is Restricted to Completely Edited Transcripts Alternative Splicing of RNA Transcripts Encoded by the Murine P105 NF-kappa B gene Generates I Kappa B Gamma Isoforms with Different Inhibitory Activities The Immediate Downstream Codon Strongly Influences the Efficiency of Utilization of Eukaryotic Translation Initiation Codons A Serine Kinase Regulates Intracellular Localization of Splicing Factors in the Cell Cycle Trp(221) is Involved in the Protective Effect of Elongation Factor EEF-2 on the Ricio/alpha-sarcin Site of the Ribosome GTP Binding to Elongation Factor EEF-2 Unmasks a Tryptophan Residue Required for Biological Activity The Human UIA SflRNP Protein Regulates Polyadenylation Via a Direct Interaction wilh Poly(A) Polymerase Cis-Elements Involved in Alternative Splicing in the Rat Beta-tropomyosln Gone -The 3'-Splice Site of the Skeletal Muscle Exon.7 is the Major Site of Blockage in Nonrnusde Cells Mutually Exclusive Exon Splicing of Type-Ill Brain sodium Channel-alpha Subunit RNA Generates Developmentally Regulated Isoforms in Rat Brain Herpes Simplex Virus DNA Replication: a Spacer Sequence Directs the ATP-dependent Formation of a Nudeoprotein Complex at Ori(S) Collection of Small Subunit (165-and 16S-like) Ribosomal RNA Structues: 1994 Further Perspective on the Catalytic Core and Secondary Structure of Ribonuclease-P RNA Molecular Cloning of a Human Small Intestinal Apolipoprotein B MRNA Editing Protein Processing of Truncated Mouse or Human RRNA Transcribed from Ribosomal Minigenes Transfected into Mouse Cells Cellular and Enzymatic Activities of a Synthetic Heteropolymer Double-stranded RNA of Defined Size Nucleolytic Inactivation and Degradation of the RNase III Processed Pnp Message Encoding Polynucleotide Phosphorylase of Escherichia Coll Roles of RNase E, RNase II and PNPase in the Degradation of the RpsO Transcripts of Escherichia Coil: Stabilizing Function of RNase II and Evidence for Efficient Degradation in an Ares Pnp Rnb Mutant alpha-2-Chimerin, an SH2-Containing GTPase-Activating Protein for the Ras-Relatnd Protein P21rac Derived by Alternate Splicing of the Human N-Chimerin Gene, is Selectively Expressed in Brain Regions and Testes Interaction of RNA Hairpins with the Human U1A N-terminal RNA Binding Domain Conserved Sequences in a Class of Rare Eukaryolic Nuclear Iotrons with Non-consensus Splice Sites Molecular Cloning and Expre~ion of RPE65, a Novel Retinal Pigment Epithelium-Specific Microsomal Protein that is Post-Transcriptionally Regulated Invitro Mapping RNA Regions in Eukaryotic Ribosomes that are Accessible to MethidiumpropyI-EDTA Center Dot Fe(ll) and EDTA Center Dot Fe(ll) Transcription of a Nematode Ul Small Nuclear RNA in Vitro -3'-End Formation Requires Cis-Acting Elements Within the Coding Sequence Specific Expression of the Human Aromatase Cylochrome-P-450 Gone by Alternative use of Multiple Exons-1 and Promoters, and Switching of Tissue-Specific Exons-1 in Carcinogenesis Role of the D.Arm and the Aoticodon Arm in Transfer RNA Recognition by Eubacterial and Eukaryotic RNase P-Enzymes Three Distinct Human Thymopoietins are Derived from Alternatively Spliced MRNAs Peeb[es CL: The Phylngenetically Predicted Base.Pairing Interaction Between Alpha and Alpha' is Required for Gronp-II Splicing Invilro A Conserved Stem Loop Structure in the 3' Untranslated Region of Prucyclin Messenger RNAs Regulates Expression in Trypanosoma-brucei Flexibility and Interchangeability of Polyadenylalion Signals in Saccharomyces Cerevisiae An Unstructured Messenger RNA Region and a 5' Hairpin Represent Impuctant Elements of the E.coli Translation Initiation Signal Delermined by Using the Bacteriophage T7 Gene 1 Translation Starl Sile Optimal Sequence and Structure of Iron-responsive Elements -Selection of RNA Stem-loops with High Affinity for Iron Regulatory Factor Enhanced Stability of Interleukin-2 Mrna in MLA 144 Cells -Possible Role of Cytoplasmic Au-Rich Seqnence-Binding Proteins The 5' End of Yeast S.BS RRNA is Generated by Exonucleases from an Upstream Cleavage Site Correct in Vivo RNA Splicing of a Milochondrial Iotron in Algal Chloroplasts Supl~resslon of Yeast RNA Polymerase III Mutations by the URP2 Gone Encoding a Protein Homologous to the Mammalian Ribosomal Protein $20 An Elaborated Pseudoknot is Required for High Frequency Frameshifting During Translation of HCV 229E Polymerase Mroa The Half-Life of C-myc Mrna in Growing and Seram-Stimulated Cells -Influence of the Coding and 3' Untranslated Regions and Role of Ribosome Trauslncation Contributions of 2'-Hydroxyl Groups of the RNA Sub6trate to Binding and Catalysis by the Tetrahymena Ribozymean Energetic Picture of an Active Site Composed of RNA The Importance of Being Ribose at the Cleavage Site in the Tetrahymena Ribozyme Reaction Comparison of PH Dependencies of the Tetrahymena Ribozyme Reactions with RNA 2'-Substituted and Phosphorothioate Substrates Reveals a Rate-Limiting Conformational Step A Kinetic and Thermodynamic Framework for the Hammerhead Ribozyme Reaction RNA/Protein Interactions in the 5'-Untranslated Leader of HspT0 Mrna in Drosophila Lysates -Lack of Evidence for Specific Protein Binding Srdl, a S-Cerevisiae Gene Affecting Pre-rRNA Processing Contains a C-2/C-2 Zinc Finger Motif Evidence for RNA Editing in Mitochondria of All Major Groups of Land Plants Except the Bryophyta The MRNA (guanine-7.)methyltransferase Domain of the Vaccinia Virus MRNA Capping Enzyme -Expression in Escherichia Coli and Structural and Kinetic Comparison to the Intact Capping Enzyme Location of the S-adenosyI-Lmethiooine Binding Region of the Vaccinia Virus MRNA (guabine-7-)methyltransferase RNA Editing of AMPA Receptor Subunit GluR-B -a Base-Paired Intron-Exon Structure Determines Position and Efficiency Probing the Hammerhead Ribozyme Structure with Ribonucleases Purification and Characterization of Human Autoaotibodies Directed to Specific Regions on U1 RNA -Recognition of Native U1 RNP Complexes A Translation-Attenuating Intraleader Open Reading Frame is Selected on Coronavirus Messenger RNAs During Persistent Infection Fe Center Dot Bleomycin Cleaves a Transfer RNA Precursor and Its Transfer DNA Analog at the Same Major Site Extension of Helix II of an HIV-t-directed Hammerhead Ribozyme with Long Antisense Flanks Does not Alter Kinetic Parameters in Vitro But Causes Loss of the Inhibitory Potential in Living Cells A GrmJp III Intron is Formed from Domains of Two Individual Group II Inlrous Sex-Lethal Autoregulation Requires Multiple Cis-Acting Elements Upstream and Downstream of the Male Exon and Appears to Depend Largely on Controlling the use of the Male Exon S' Splice Site Sequence-specific Cleavage of Oligoribonocleotide Capable of Forming a Stem and Loop Structure POly(A) Site Selection in the Yeast Ty Retroelement Requires an Upstream Region and Sequence-Specific Titratable Factor(s) in Vitro Polyadenylation of the Mrna of Hepatitis Delta Virus is Dependent on the Structure of the Nascent RNA and Regulated by the Small or Large Delta Antigen Mutational Analysis of the PRP4 Protein of Saccharomyces Cerevisiae Suggests Domain Structure and SnRNP Interactions Alteration of splice Site Selection by an Exon Mutation in the Human Glycophorin-A Gene Remodeling of the Trammembran~ Segment in Human Glycophorin by Aberrant RNA Splicing The M(r) 35,000 Beta-Adrenergic Receptor Me,~enger RNA-Bindiog Profein Induced by Agonists Requires Both an AUUUA Pentan~r and U-Rich Domains for RNA Recognition The C.Prutein Tetramer Binds 230 to 240 Nucleotides of P~.Messenger RNA and Nucleates Ihe Assembly of 40s Heterogeneous Nuclear Ribunucleoprotein Particles In Vivo • Analysis of the Stabilily and Transport of Nuclear Poly CA) + RNA Two Inactive Fragments Derived from the Yeast Mitochondrial Ribosomal Protein MrpS28 Function In-Trans to Support Ribosome Assembly and Respiratory Growth Regulation of Allernative Pre-mRNA Splicing by a Novel Repeated Hexaoncleolide Element RNA 3' End Signals of the S.pombe Ura4 Gene Comprise a Site Determining and Efficiency Element Cell-specific Translational Control of Transcription Factor BTEB Expression -Role of an Upstream AUG in the 5'-untranslated Region A Hammerhead Ribozyme Inhibits the Proliferation of an RNA Coliphage SP in Escherichia Colt Ribozymes -Time to Change Partners Saturation Mutagenesis of a Polyadeny|y|ation Signal Reveals a Hexanucleotide Element Essential for Me-~enger-RNA 3' End Formation in Saccharomyces-cerevlslae Protein Complex Involved in Pre-mRNA Splicing Phorbof Esters and Norepinephrine Destabilize Alpha(1 B)-adrenergic Receptor Messenger RNA in Vascular Smooth Muscle Cells Monitoring of the Cooperative Unfolding of the SunY Group-I Inlron of Bacteriophage-T4 -the Active Form of the SunY Ribuzyme is Stabilized by Multiple Interactions with 3' Terminal Intron Components Processing of Gonadotropin-Releasing Hormone Gene Transcripts in the Rat Brain Rapamycin Selectively Represses Translation of The ~polypyrimidine Tract ~ MRNA Family Identification of Phosphate Oxygens that are Important for Self-cleavage Activity of the HDV Ribozyme by Phosphorothioate Substitution Interference Analysis Glass Rh RNA Sequence of Astrovinss -Distinctive Genomic Organization and a i~Jtative Retrovirus-Like Ribosomal Frameshiffing Signal that Directs the Viral Replicas• Synthesis An Intron in the Nuclear Ribosomal DNA of Didymium Iridis Codes for a Group I Ribuzyme and a Novel Ribuzynse thai Cooperate in Self-Splicing Isolation and Characterization of Saccharomyces Cervisiae mRNA Transporl-defective (mtr) Mutants • Nuclear MRNA Accumulation Causes Nucfeolar Fragmentation in Yeast rote2 mutant • SubceHular Distribution of Human Immunodeficiency Virus Type 1 Rev and Colocalization of Rev with RNA Splicing Factors in a speckled Pattern in the Nucleoplasm Translation of Encephalomyocarditis Virus RNA -Parameters Influencing the Selection of the Internal Initiation Site The Conserved Pre-Messenger RNA Splicing Factor-U2AF from Drosophila -Requirement for Viability Role of U6 SnRNA in 5' Splice Site Selection Formation of Sheared G:A Base Pairs in an RNA Duplex Modelled after Ribozymes, as Revealed by NMR AU-A, an RNA-binding Activity Distinct from HnRNP A1, is Selective for AUUUA Repeats and Shuttles Between the Nucleus and the Cytoplasm Artificial Self-Cleaving Molecules Consisting of a Transfer RNA Precursor and the Catalytic RNA of RNase-P Transcription and Editing of Cytochrome Oxidase-II RNAs in Trypanosoma-cmzi Diversified Sequences of Peptide Epitope for Same-RNA Recognition Elongation Factor 2 Mutants Deficient in Diphthamide Formation Show Temperature-Sensitlve Cell Growth An Alternatively Spliced Form of HLA-G MRNA in Human Tropbublasts and Evidence for the Presence of HLA-G Transcript in Adult Lymphocytes A Cis-Acting Selector of a 5' Splice Site -Cooperation Between the Sequence of the Site and an Upstream Exonic Element Inhibition of Protein Synthesis Alters the Subcellular Distribution of Messenger RNA in Neurons But Does not Prevent Dendritic Transport of RNA Angiotensin-II Stimulates the Synthesis of Angintensinogen in Hepatncytes by Inhibiting Adenylylcydase Activity and Stabilizing Angiotensinogen Messenger RNA Delncalization of Vgt MRNA from the Vegetal Cortex in Xenopus Oocyles after Destruction of Xlsirt RNA Translational Repression of Endogenous Thymidine Kinase Messenger RNA in Differentiating and Arresting Mouse Cells Mutually Exclusive and Cassette Exons Undedie Alternatively Spliced Isoforms of the Na/Ca Exchanger Protein-Proteln Interactions and 5'-Splice-Site Recognition in Mammalian Mrna Precursors Different frypanosoma Brucei Guide RNA Molecules Associate with an Identical Complement of Mitochondrial Proteins in Vitro A TRNA-like Structure is Present in 10Sa RNA, a small Stable RNA from Escherichia CoIL Proc Nat/Acad Sci U 5 A Konarska MM: U4/US/U6 SnRNP Recognizes the 5' Splice Site in the Absence of U2 SnRNP Disruption of Base Pairing Between the 5' Splice Site and the 5' End of U1 SnRNA is Required for Spliceosome A~embly Analysis of the Translational Initiation Region on the Euglena Gracilis Chloroplast Ribulnse-Bisphnsphate Carboxylase/Oxygenase (RbCI) Messenger RNA Effect of the Secondary Struclure in the Eoglena Gracilis Chloroplast Ribulose-Bisphnsphale Carboxylase/Oxygenase Messenger RNA on Translational Initialion Mutational Analysis of the C-terminal Region of Saccharomyces Cerevisiae Ribosomal Protein L25 in Vitro and in Vivo Demonstrates the Presence of Two Distinct Functional Elements A Novel RNA-binding Molif in Omnipolenl Suppressors of Translation Termination, Ribosomal Proteins and a Ribosome Modification Enzyme? Stimulation of Gene Expression by Inlrons -Conversion of an Inhibitory Intron to a Stinmlatory Intron by Alteration of the Splice Donor Sequence Effect of Dexamethasone on the Alternative Splicing of the Insulin Receptor Messenger RNA and Insulin Action in HepG2 Hepatoma Cells The Role of Posltranscrlplional Modification in Stabilization of Transfer RNA from Hyperthermophiles Features in the 5' Non-coding Sequences of Rabbit-alpha and Beta-Globin Messenger RNAs that Affect Translational Efficiency Tbe Concentration of B52, an Essential Splicing Factor and Regulator of Splice Site Choice in Vitro, is Critical for Drosophila Development Regulation of Adenovirus Alternative RNA Splicing at the Level of Commitment Complex Formation The Genes for Transcription Factor Nuclear Factor I Give Rise to Corresponding Splice Variants Between Vertebrate Species Endogenous P53 Protein Generated from Wild-Type Alternatively Spliced P53 RNA in Mouse Epidermal Cells Chemical Probing Studies of Variants of the Genomic Hepatitis Delta Virus Ribozyme by Primer Extension Analysis Two Major Tertiary Folding Transitions of the Telrahymena Catalytic RNA Functional Differences Among Alternatively Spliced Variants of Slowpoke, a Drosophila Calcium-activated Potassimn Channel Nuclear Retention of the Induced Messenger RNA Following Amino Acid-Dependent Transcriptional Regulation of Mammalian Ribosomal Proteins L17 and $25 and Around SNRPN Modulation of Human Saposin B Sphingollpid-binding Specificity by Alternative Splicing -a Study with Saposin B-derived Synthetic Peptides Phylogenetic Analysis of RNA Editing -a Primitive Genetic Phenomenon Initiation Factor EIF-4E of Saccharomyces Cerevisiae -Distribution Within the Cell, Binding to Mrna, and Consequences of Its Overproduction The Cellular Concentration of the Sigma(S) Subunit of RNA Polymerase in Escherichia Colt is Controlled at the Levels of Transcription Translation, and Protein Stabilily Reduced Beta 2-microglobulin MRNA Levels in Traosgenic Mice Expressing a Designed Hammerhead Ribozyme Dimeric Structure of a Human Apolipoprolein B MRNA Editing Protein and Cloning and Chromosomal Localization of its Gene Chabot 8: A Splicing Enhancer in the Human Fibronectin Alternate ED1-Exon Interacts with St-Proteins and Stimulates U2-snRNP Binding Idenlification of a novel Type of Alternative Splicing of a Tyrosine Kinase Receplor -Juxtamembrane Deletion of the C-met Prolein Kinase C Serlne I~osphorylation Regulatory Site Agonisl-Mediated Destabilizalion of M1 Muscarinic Acetylcholine Receptor Mrna -Elements Involved in Mroa Stabilily are Localized in the 3'-Untranslated Region Mutations in U6 SnRNA thai Alter Splice Site Specificity -Implications for the Active Site Novel Gene Expression Mechanism in a Fission Yeast Retroelemenl -Tfl Proleins are Derived from a Single Primary Translation Product Casjens 5R: A Programmed Translalional Frameshiff is Required for the Synthesis of a Bacteriophage-lambda Tail Assembly Protein Translational Positioning of a Nudeosumal Glucocorticoid Response Element Modulates Glucocorticoid Receptor Affinily Derivatives of the Yeast Mitochondrial Ribosomal Protein MrpS2B Replace Ribosomal Protein-S15 as Functional Components of the Escherichia-coli Ribosome Role of Individual Exoribonucleases in Processing al the 3' End of Escherichia Colt TRNA Precursors Inhibition of Herpes Simplex Virus Infection by Ectopic Expression of Neuronal Splice Variants of the Oct-2 Transcription Factor Mutations that Increase the Affinity of a Translational Repressor for RNA Altering Ihe RNA Binding Specificity of a Translational Repressor Lim Vh Analysis of Action of Wobble Nucleoside Modifications on Codon-anticodon Fairing Within the Ribosome Evidence that the Guanusine Substrale of the Telrahymena Ribozyme is Bound in the Anti Conformation and thai N7 Contribules to Binding Isulatiou and Characterization of CDNA Clones for Chloroplast Translalional Initiation Factor-3 from Euglena Gracilis PHAS-1 as a Link Between Milogen-activated Protein Kinase and Translalion Inilialion Effects of Nocleotide Sequence on the Specificity of Rne-Dependent and RNase E-Mediated Cleavages of RNA I Encoded hy the Pbr322 Plasmid Membrane Cofactor Protein (Cd46) of Complement -Processing Differences Related to Alternatively Spliced Cytoplasmic Domains Differential Evolution of Substrates for an RNA Enzyme in the Presence and Absence of Its Protein Cofactor Poiyadenylalion Site Selection Cannot Occur Invlvo after Excision of the 3'-Terminal Inlron Targeted Nuclear Anlisense RNA Mimics Natural Antisense-indoced Degradation of Polyoma Virus Early RNA. Proc Nail Acad 5ci U S A Commitment of Yeast Pre-mRNA Io the Splicing Pathway Requires a Novel U1 Small Nuclear Ribonucleoprolein Polypeplide, Prp39p Kinetic Characterization of Inlramolecular and Intermolecular Hammerhead RNAs with Slem II Deletions Coordinate Translational Regulation in the Syntheses of Elongation Factor-t Alpha and Ribosomal Proteins in Xenopus-laevis Low Cytoplasmic MRNA Levels of Immunoglol~lin Kappa Light Chain Genes Containing Nonsense Codons Correlate with Inefficient Splicing The Influenza Virus NS1 Protein: a Novel Inhibitor of Pre-mRNA Splicing Isolation of U3 SnoRNP from CHO Cells -a Novel 55 KDa Protein Binds to the Central Part of U3 SnoRNA Intron Creation and Polyadenylation in Maize are Directed by Au-Rich RNA RNA Binding Properties of Vacclnla Virus Capping Enzyme Direct Interaction of the U1 SnRNP-A • Protein with the Upstream Efficiency Element of the SV40 Late Poiyadenylalion Signal The POP1 Gene Encodes Protein Component Common to Ihe RNase MRP and RNase P Ribonucleoproteins The 64kD Subunit of • the CstF Polyadenylatiou Factor Binds Io Pre-mRNAs Dowmtream of the Cleavage Site and Influences Cleavage Site Location The Role of RNA Structure in Determining RNase E-Dependenl Cleavage Sites in the Messenger RNA for Ribosomal Protein Direct Genetic Selection for a Specific RNA -Protein Interaction Randomization-Selection Analysis of Sornas in Vivo -Evidence for a Tertiary Interaction in the Spliceosome Genetic Interactions Between the Yeast RNA Helicase Homolog Prp16 and Spliceusomal SnRNAs Identify Candidate Ligands for the Prp16 RNA.dependent ATPase Import of Small RNAs into Leishmania Milochondria in Vitro Editing of the Mitochondrial Small Subunit RRNA in Physamm Polycephalum Poly(ADP-ribose) Molecules Formed During DNA Repair in Vivo A Quantitative Model of the Escherichia Colt 16 S RNA in the 30 DNA Damaging Agents Increase the Stability of Interleukin-1 Alpha, Interleukin-1 Beta, and Inlerleukin-6 Transcripts and the Production of the Relative Proteins The Milogen-Regulated Prolein/Proliferin Transcript is Degraded in Primary Mouse Embryo Fibroblast Bul not 3T3 Nuclei -Altered RNA Processing Correlates with In'mlorlalization RNA 3' Ends -Formation and Function -Meeting Review Positive and Negative Regulation of Retinold X-Receptor Gene Expression by Thyroid Hormone in the Rat -Transcriptional and Post.Transcriptiooal Controls by Thyroid Hormone GAG Triplets as Splice Acceptors of Lasl Resort -an Unusual Form of Alternative Splicing in Prothymosin-alpha Pre-Messenger RNA Editing Corrects Mispairing in the Acceplor Stem of Bean and Potato Milochondrial Phenylalanine Transfer RNAs Dimerizalion of Human Immunodeficiency Virus Type 1 RNA Involves Sequences Located Upstream of the Splice Donor Site Overproduction and Purificalion of Native and Queuine-Lacking Escherichia-coli Transfer RNA(Asp) A Mef2 Gene thai Generates a Muscle-Specific Isofc~rm Via Allerualive Mrna Splicing On the Relalionship Between Preferred Termination Codon Contexts and Nonsense Suppression in Human Cells The Stereochemical Course of the First Slep of If'e-Messenger RNA Splicing Simpson 1: Evolution of RNA Editing in Kinetoplastid Protozoa Gene Slruclore of Human Milochondrial ATP Synlhase Gamma-Subunit -Tissue Specificity Produced by Allernatlve RNA Splicing Genetic Evidence for IS1 Transposition Regulated by ImA and the Delta lusA-B'-InsB Species, Which is Generated by Translation from Two Alternative Inlemal Initiation Sites and Frameshiffing The Hnrnp F Protein -Unique Primary Slructure, Nucleic Acid-Binding Properlles, and Subceliular Localizalion Intermolecular Disintegration and Intramolecular Strand Transfer Activities of Wild-Type and Mutant HIV-1 Integrase Rules that Govern Transfer RNA Identity in Protein Synthesis Correlation of Translation Efficiency wilh the Decay of LacZ MRNA in Escherichia Coll AU-Rich Inlronic Elements Affect Pre-Messenger RNA 5' Splice Site Selection in Drosophila-melanogasler A+u Content Rather Than a Particular Nucleotide Order Determines the Specificity of RNase E Cleavage RNA Splicing Regulates the Activily of a Sh2 Domain-Containing Protein Tyrusine Phosphatase Intragenic Processing in Yeast RRNA is Dependent on tile 3' External Transcribed Spacer Proteolytic Degradation of MAD3 (I Kappa B Alpha) and Enhanced Processing of the NF-kappa B Precursor P105 are Obligatory Steps in the Activation of NF-kappa B Cloning and Characterization of CDNA Encoding Rat Hemin-Sensitive Initiation Factor-2 Alpha Alpha) Kinase -Evidence for Multilissue Expression Casein Kinase II is Implicaled in the Regulation of Heme-Controiled Translalional Inhibitor of Reticulocyle Lysates Correlation Between the Presence of a Self-Splicing Intron in The 25S RDNA of C-Albicans and Strains Susceptibility TO S.Fluorocylnsine The Translalion Initiation Faclor-elF-4B Contains an RNA-Binding Region that is Distinct and Independent from Its Ribouucleoprolein Consensus Sequence Ribosomal Protein-L25 from Trypanosoma-brncei -Phylogeny and Molecular Co-Evolution of an RRNA-Binding Protein and Its RRNA Binding Site The HIV-1 Rev trans-activator • Shuttles Between the Nucleus and the Cytoplasm Heat Shock Affects 5' Splice Site Selection, Cleavage and LiBation of CAD Pre-mRNA in Hamster Cells, But not Its Packaging in InRNP Particles Circadian Expression of the Luciferin-binding Protein Correlates with the Binding of a Protein to the 3' Untranslated Region of Its MRNA Lambowitz AM: A Tyrnsyl-tRNA Synthetase can Function Similarly to an RNA Structure in the Tetrahymena Ribozyme Mulations in Helix 34 of Escherichia Colt 16 S Ribosomal RNA have Multiple Effects on Ribosome Function and Synthesis Structure of 2 Rat Genes Coding for closely Related Rolipram-Sensitive CAMP Pho~phodiesterases -Multiple Mes~.enger RNA Variants Originate from Alternative Splicing and Multiple Start Sites The GTP-binding Protein Ran/TC4 is • Required for Protein Import into the Nucleus A G Protein in Nucleucytoplasmic ee Transport: the Role of Ran Functional Expression and Properties of the Transfer RNA(Lys)-Specific Core Anticodon Nuclease Encoded by Escherichia-coll-prrC Splicing Defective Mutants of the COXI Gene of Yeast Mitucbondrial DNA: Initial Definition of the Maturase Domain of the Group II Intron AI2 Characterization of the DNA-Binding Properties of the Myeloid Zinc Finger Protein Mzfl -Two Independent DNA-Binding Domains Recognize Two DNA Consensus Sequences with a Common G-Rich Core An Alternative Pathway of Histone MRNA 3' End Formation in Mouse Round Spermatids Coofonnational Analysis of the S' Leader and 1he GAG Initiation Site of Mo-MuLV RNA and AIInsteric Transitions Induced by Dimerization Deadenylation of the Unstab4e Mrna Encoded by the Yeast Mfa2 Gene Leads to Decapping Followed by 5'--~3' Digestion of the Transcripl Premature Translational Termination Triggers MRNA Decapping Elongation Factor EF-1 Delta, a New Target for Maturalionpromoting Factor in Xenopus Oocytes Gaaa Tetraloop and Conserved Bulge Stabilize Tertiary Structure of a Group I Intron Domain Alternative Splicing of the Guanine Nucleolide-Binding Regulalory Prolein-G(O Alpha) Generates Four Distinct Messenger RNAs A CAMP-Regulated RNA-Binding Protein that Interacts with Phnsphoenolpyruvate Carboxykinase (GTP) Messenger RNA An Alternative Transcript of the Chick Type III Collagen Gene thai Does not Encode Type III Collagen Aua-Cleaving Hammerhead Ribozymes -Attempted Selection for Improved Cleavage Yeast Lariat Debraoching Enzyme -Substrate and Sequence Specificity Multiple Instabililyregulating Sites in the 3' Untranslated Region of the Urokinase-type Pla~minogen Activator MRNA Two Structural Domains of Initiation Factor EIF-4B are Involved in Binding to RNA Truncated Transfer RNA(Arg) is Essential for invitro Specific Cleavage of Partially Synthesized Mouse 185 RRNA The P27 Catalytic Subonit of the Apolipoprotein-B Messenger RNA Editing Enzyme is a Cytidine Deaminase Post-Transcriptional Down-Regulation of Expression of Transcription Factor Nfl by Ha-Ras Oncogene Invivo Cooperation Between Introns During Pre-Me~enger RNA Processing The Association of the Ul-specific 70K and C proteins with U1 SnRNPs is Mediated in Part by Common U SnRNP Proteins Upstream Introns Influence the Effaciency of Final Intron Removal and RNA 3'-End Formation Protein Synthesis: Cradle at the Ribosome Determinants for Stability of the Chloroplast PsbD RNA are Located Within Its Short Leader Region in Chlamydomonas Reinhardtii RNA-RNA Interactions in the Splieeosome: Unraveling the Ties that Bind Human Adenovirns Encodes 2 Proteins Which have Opposite Effects on Accuctmlafion of Alternatively Spliced Messenger RNAs Regulation of Human Insulin Receptor RNA Splicing in Vivo Polypyrimidine Tract Sequences Direct Selection of Alternative Branch Sites and Influence Protein Binding Coupling Between Genome Translation and Replication in an RNA Virus Synthesis of Staphylococcal Virulence Factors is Controlled by a Regulatory RNA Molecule Ph The Effect of Sequences with High AU Content on Messenger RNA Stability in Tobacco The Conserved 3'-Flanklng Sequence, Aatggaaatg, of the Wheat Histone H3 Gene is Necessary for the Accurate 3'-End Formation of Mrna Klein h Posttranscriptional Modification of Myosin Heavy-Chain Gene Expression in the Hypertrophied Rat Myocardium Translational Repression by the Human Iron-Regulatory Factor (IRF) in Saccharomyces-cerevisiae Translation of 15-Lipoxygenase MRNA is Inhibited by a Protein that Binds to a Repealed Sequence in the 3' Untranslated Region Selective Cleavage of BCR-ABL Chimeric RNAs by a Ribozyme Targeted to Non-Conliguo~ Sequences The Ubiquitin-proteasome Pathway is Required for Processing the NF-KBt Precursor Protein and the Activation of NF-KB Cloning and Expression of 2 Structurally Distinct Receptor-Linked Protein-Tyrnslne Phosphatases Generated by RNA Processing from a Single Gene Point Mutations in the Stem-Loop at the 3' End of Mouse Histone Mrna Reduce Expression by Reducing the Efficiency of 3' End Formation Aebi U: • Interactions and Three Dimensional Localization of a Group of Nuclear Pore Complex Proteins. I Cell DNA Strand Break-mediated Partitioning of Poly(AOP-rlbose) Polymerase Function The Peptide Product of a 5' Leader Cistron in the Beta(2) Adrenergic Receptor Mrna Inhibits Receptor Synthesis Insulin-dependent Stimulation of Protein Synthesis by Phosphorylation of a Regulator of 5'-cap Function The HRIGRXXR Region of the DEAD Box RNA Helicase Eukaryotic Translation Initiation Factor-4A is Required for RNA Binding and ATP Hydrolysis Dominant Negative Mutants of Mammalian Translation Initiation Factor EIF-4A Define a Critical Role for EIF-4F in Cap-Dependent and Cap-Independent Initiation of Translation Alternatively Spliced Isoforms of the Putative Renal Na-K-CI Cotransporter are Differentially Distributed Within the Rabbit Kidney Sigman DS: Footprinting RNA -Protein Complexes Following Gel Retardation Assays: Application to the R-17-procoat -RNA and Tat -TAR Interactions Sequence and Structural Elements Critical for U8 SnRNP Function in Xenopns Oocytes are Evolulionarily Conserved Single Point Mutations in Domain-II of the Yeast Mitnchondrial Release Factor MRF-1 Affect Ribosome Binding Alternative MRNA Splicing Generates Tissue-specific Isoforms Of 116-kDa Polypeptide of Vacuolar Proton Pump Characterization of Two Classes of Ribonucleoprotein Complexes Possibly Involved in RNA Editing from Leishmania Tarentolae Mitochondria Functional Analysis of Messenger RNA 3' End Formation Signals in the Convergent and Overlapping Transcription Units of the S.cerevisiae Genes RHO1 and MRP2 Exon Size Affects Competition Between Splicing and Cleavage-Polyadenylation in the Immunoglobulin-mu Gene P2 Functions as a Spacer in the Tetrahymena Ribozyme Structural Elements of RpsO MRNA Involved in the Modulation of Translational Initiation and Regulation of E.coli Ribosomal Protein $15 Starting Window, a distinct Element in the Cap-independent Internal initiation of Translation on Picornaviral RNA Positions 13 and 914 in Eschericbia Colt 165 Ribosomal RNA are Involved in the Control of Translational Accuracy Cap Hypermethylation of U1 Small Nuclear Ribonucleoprotein (snRNP) in Vitro: Evidence that the U1 Small Nuclear RNA-(guannsine-N2)-methyltransferase is a Non-snRNP Cytoplasmic Protein that Requires a Binding Site on the Sm Core Domain A Dominant Negative Mutation in the Conserved RNA Helicase Motif Sat Causes Splicing Factor Prp2 to Stall in Spliceosomes Synthetic RNA-Cleaving Molecules Mimicking Ribonoclease a Active Center -Design and Cleavage of TRNA Transcripts Eicosanoid Metabolism in Cholesterol-Enriched Arterial Smooth Muscle Cells -Evidence for Reduced Posttranscriptional Processing of Cyclooxygenase-I and Reduced Cyclouxygenase-II Gene Expression Separation of Mutant and Wild-Type Ribosomes Based on Differences in Their Anti Shine-Dalgamo Sequence Contrasted Cis-acting Effects of Downstream 5' Splice Sites on the Splicing of a Retained Intron -the Adenoviral E1 A Pre-Messenger RNA Model U2AF Homolog Required for Splicing In-Vivo Identification of Bovine Glutamate Dehydrogenase as an RNA-Binding Protein Sequence Elements Upstream of the 3' £ 1 ~vage Site Confer Subs]rate Strength to the Adenovirus L1 and L3 Pniyadenylalion Sites Methylphnsphonate Mapping of Phosphate Contacts Critical for RNA Recognition by the Human Immunodeficiency Virus Tat and Rev Proteins Purification and Properties of a Protein that Binds to the C-Terminal Coding Region of Human C-myc Mrna Translation: Turned on by Insulin Expanding the Scope of RNA Catalysis Building a Kinetic Framework for Group II Inlron Ribuzyme Activity -Quantitation of Interdomaln Binding and Reaction Rate Two Functional • Domains of the Influenza Virus NS1 Protein are Required for Regulation of Nuclear Expori of MRNA The Influenza Virus NS1 Protein is a • Puly (A)-bindiog Protein thai Inhibits Nuclear Export OF MRNAs Containing Puly (A) GRSF-I: a Poly(A)(+) MRNA Binding Protein Which Interacts with a Conserved G-rich Element Branch Nucleopbile Selection in Pre-Mrna Splicing -Evidence for the Bulged Duplex Model Poly(A) Polymerase • Contains Multiple Functional Domains Expression of Mutant Eukaryotic Initiation Factor 2 Alpha Subunit (elf-2 Alpha) Reduces Inhibition of Guanine Nudeotide Exchange Activity of EIF-2B Mediated by Elf-2 Alpha Phosphoryialion NMR Evidence for the RNA Stem-Loop Structure Involved in the Transcription Attenuation of E.culi Trp Operon RD: cis-Acting Elements in the 5'-Untranslated Region of Rat Testis Proenkephalin Messenger RNA Regulate Translation of the Precursor Protein Tumor Suppression by RNA from the 3' Untranslated Region of Alpha-Tropomyosin Alternative Splicing Produces a divergent Cytoplasmic Tail in the Human Endothelial Thromboxane A(2), Receptor Assembly of Mitochondrial Ribonucleoprolein Complexes Involves Specific Guide RNA (gRNA)-Binding Proteins and Groa Domains But Does not Require Preedited Messenger RNA Editing of Trypanosoma Brucei Maxicircle CR5 MRNA Generates Variable Carboxy Terminal Predicted Protein Sequences Adenosine Receptor Gene -Evidence for Alternative Splicing Posttranscriptional MRNA Processiog as a Mechanism for Regulation of Human A(1) Adenosine Receptor Expression Multiple Guide RNAs for Identical Editing of Trypanosuma Rrucei Apocytochrome B Mrna have an Unusual Minicircle Location and are Developmentally Regulated The Trar~activation Potential of Variant Hepatocyte Nuclear Factor-1 is Modified by Alternative Splicing Translation Initiation Complex Formation with 30-S Ribosomal Particles Mutated at Conserved Positions in the Y-Minor Domain of 16-S RNA Nature of the Ribosomal Messenger RNA Track -Analysis of Ribosome-Binding Sites Containing Different Sequences and Secondary Structures Recognition of the Mrna Selenocysteine Insertion Sequence by the Specialized Translational Elongation Factor Selb Contacts Between 165 Ribosomal RNA and MRNA, Within the Spacer Region Separating the AUG Initiator Codon and the Shine Site-directed Cross-linking Study Novel Genes Required for Ribosome A~embly and Function in Saccharomyces-cerevisiae Induction of Cyclor)xygenase-2 by Interieukin-1 Alpha -Evidence for Post-Transcriptional Regulation Pulynucleolide Phosphorylase of Escherichia Colt Induces the Degradation of Its RNase III Processed Me~.enger by Preventing Its Translation TPD1 of Saccharomyces Cerevisiae Encodes a Protein Phosphatase 2C-like Activity Implicated in TRNA Splicing and Cell Separation Translational Enhancement of H-ferritin MRNA by Interleukin.1 Beta Acts Through 5' Leader Sequences Distinct from the Iron Responsive Element Polyamines Regulate the Expression OF Omitbine Decarhoxylase Antizyme in Vitro by Inducing Ribosomal Frame-Shifting The U1 Small Nuclear Ribonucleoprotein (snRNP) 7OK Protein is Traosl~'led Independently of U1 SnRNP Particles Via a Nuclear Localization Signal in the RNA-binding Domain RNA Travel -Tracks from DNA to Cytoplasm Elevated Levels of Cyclin D1 Protein in Response to Increased Expression of Eukaryotic Initiation Factor 4E The Contribution of AAUAAA and the Upstream Element UUUGUA to the Efficiency of MRNA 3'-end Formation in Plants Pores for Thought: Nuclear Pore ee Complex Proteins Cell-specific Translational Regulation of S-adenosylmntbionine Decarboxylase MRNA -Influence of the SIructure of the 5' Transcripl Leader on Regulation by the Upstream Open Reading Frame Bradyrhizobium-japoNcum Rhizobitoxine Genes and Putative Enzyme Functions -Expression Requires a Four Yeast Spliceosumal Proteins (PRPS, PRPg, PRP11, and PRP21) interact to Promote 02 SnRNP Binding to Pre-Messenger RNA Minimal]st Aminoacylated RNAs as Efficienl Substrates for Elongation Factor Tu Complete RNA Editing of Unspliced and Oicistronic Transcripts of the Intron-Containing Reading Frame Irft 70 from Maize Chloroplasts Extremely Short 20-33 Nuclentide Introns are the Standard Length in Paramecium Tetraurelia Signak that Produce 3' Termini in CYC1 Messenger RNA of the Yeast Saccharumyce~cerevisiae Co~aled Replication.Translation of Amplifiable Messenger RNA. a Cell-Free Prolein Synthesis Syslern that Mimics Viral Infection Poly(A) Tail Metabolism and Function in Eocaryotes The Influence of 5'-Secondary Structures Upon Ribosome Binding to Messenger RNA During Translation in Yeast Ral~d MRNA Degradation in Yeast can Proceed Independently of TransJationaJ Elongation A Defective Human Foamy Provirus Generated by Pregenome Splicing Transcriptional Regulation of the Str Operon in Eschericbia Colt . Ribosomal Protein-S7 Inhibits Coupled Translation of $7 But not Its Independent Translation Post-Transcriptional Regulation of the Str Operon in Escherichia Colt -Structural and Mutational Analysis of the Target Site for Translational Reprehend, or-S7 petD MRNA Maturation in Chlamydomonas Reinhardtii Chloroplasts: Rule of 5' Endonocleolytic Proce~ing RNA Binding by Sxl Proteins in Vitro and in Vivo Unprocessed Myogenio Transcripts Accumulate During MOUSe Embryogenesls Similar Alternative Splicing of a Non-homniogous Domain in Beta A4-amyloid Protein Precursor-llke Proteins Dual Role of the Sequence-Specific Bacteriophage-T4 Endoribonuclease RegB -Me~enger RNA Inactivation and Me~enger RNA Destabilization ] E, 8ozzoni h RNAprotein Interactions in the Nuclei of Xenopus Oooftes: Complex Formation and Processing Activity on the Regulatory Intron of Ribosomal Protein Gene L1 A Shortened Form of the Tetrahymena-thermophila Group-I Intron can Catalyze the Complete Splicing Reaction Intrans Enhancement of the Cleavage Rates of DNA-Atmed Hammerhead Ribozymes by Various Divalent Metal Ions The Site of 3' End Formation of Histone Messenger RNA is a Fixed Distance from the Downstream Element Recognized by the U7 SnRNP Multiple Elements in the C.fos Protein-Coding Region Facilitate Messenger RNA Deadenylation and Decay by a Mechanism Coupled 1o Translation Mutational Isolation of a Sieve for Editing in a Transfer RNA Synthetase Nuclear RNa~e MRP is Reqoired for Correcl Processing of Pre-5.8S RRNA in Saccharomyces-cerevisiae Effect of 5-fluoro-and 5-bromouracil Substitution on the Translation of Human Thymidylate Syuthase MRNA Splicing and 3'-Proce~ing of the Tyroslne Transfer RNA of Trypanosoma-heucei Mutalional Analysis of a Multifunctional Protein, with MRNA 5' Capspecific (nucleuside-2'.O-)-methyltransferase And 3'-adenylyltransferase Stimulatory Activities, Encoded by Vaccinia Virus Three Tetrahymena TRNA(GIn) Isoacceptors as TOOLS four Studying Unorthodox Codon Recognition and Codon Context Effects During Protein Synthesis in Vitro Transfer RNA Mutation and the Malleability of the Genetic Code Transfer RNA Structure and Ribosomal Function. 1. Transfer RNA Nucleotide-27-43 Mutations Enhance First Position Wobble Tran~er RNA Structure and Ribosomal Function. 2. Interaction Between Anticodon Helix and Olher Transfer RNA Mutations. l Mol Roditi h Accurale Polyadenylation of Procyclin MRNAs in Trypanosoma Brucei is Determined by Pyrimidine-rich Elements in the Intergenic Regions Mutational Analysis of Yeast MRNA Capping Enzyme Interleukin-2,Dependent Transcriptional and Pnst-Trarncriptional Regulation of Traosferrin Receptor Messenger RNA RNA Editing: Transfer of Genetic Information from GRNA to Precursor MRNA in Vitro Translational Control in Production of Traosl~sase and in TranSposition of Insertion Sequence-IS3 Genetic and Biochemical Analysis of lhe Fission Yeast Ribonocleoprntein Particle Coutaining a Homolng of Srp54p Physiologic Concentrations of Glucose Regulale Falty Acid Syntha.~ Activity in HepG2 Cells by Mediating Fatty Acid Syntha~ Messenger RNA Stabilily The RatPDE3/IVd Phosphodiesterase Gene Codes for Multiple Proteins Differentially Activated by CAMP-dependeut Protein Kinase The RaIPDE3/IVd Phnsphodiesterase Gene Codes for Multiple Proteins Differentially Activated by CAMP-dependent Protein Kinase RNA Editing in the Wilms' Tumor Susceptibility Gene, WT1 The 3'-Unlranslated Regions of C-MOS and Cyclin MRNAS Stimulate Translation by Regulating Cytoplasmic Polyadenylation Conformation of the Central, Three-helix Junction of the 5 S Ribosomal RNA of Sulfolobus Acidocaldarios Growth Factor-Inducible Alternative Splicing of Nootransmembrane Phosphotyrnsine Phosphataso PTP-I B Pre-Messenger RNA Protein Synthesis Elongation Factor EF-1 Alpha Expression and Longevity in Drosophila Melanogaster Purification of Human U6 Small Nuclear RNA Capping Enzyme . Evidence for a Common Capping Enzyme for Gamma-Monurnethyl-Capped Small RNAs cDNA Cloning of PG-M, a Large Chondroilin Sulfate Proteoglycan Expressed During Chondrogenesis in Chick Limb Buds -Allernafive Spliced Multiforms of PG-M and Their Relationships to Versican Milochondrial Transcripts are Processed But are not Edited Normally in Trypanosoma Equiperdum (ATCC 30019) Which Has KDNA Sequence Deletion and Duplication Methylphosphale Cap Structure Increases the Stability of 7SK, B2 and U6 Small RNAs in Xenopus Regulation of Tissuespecific P-element Pre-mRNA Splicing Requires the RNA-binding Protein PSI Codon Reading Scheme in Mycoplasmapneumoniae Revealed by the Analysis of Ihe Complete Set of Transfer RNA Genes RNA Editing and the Evolution of Parasites Post-Transcriptional Regulation of Rat Alpha Cardiac Myosin Heavy Chain Gene Expression A Yeast Protein that Bidirectionally Affects Nucleocytoplasmic Transport Essential Role for KH Domains in RNA Binding: Impaired RNA Binding by a Mulatio~ in the KH Domain of FMRt thai Causes Fragile X Syndrome Upstream and Downslream Cis-Acting Elements for Cleavage al the L4 Polyadenylalion Site of Adenovirus-2 Ehresmann C: Identification of the Primary Site of the Human Immunodeficiency Virus Type 1 RNA Dimerization in Vitro Slructural Characterization and Alternate Splicing of the Gene Encoding Ihe Preadipocyte EGF-like Protein Pref-1 Ribosomal Pausing During Translation of an RNA Psendoknot The U5 and U6 Small Nuclear RNAs as Active Site Components of Ihe Spliceosome High Cooceutrations of Ppgpp Decrease the RNA Chain Growth Rate -Implications for Protein Synlhesis and Traoslalional Fidelity During Amino Acid Starvation in Escherichia Colt A Novel Tissue-Specific Calpain Species Expressed Predominantly in the Stomach Comprises Two Alternative Splicing Producls with and without Ca2+-Binding Domain Extensive Editing of CR2 Maxicircle Transcripts of Trypanosoma-brueel Predicts a Protein with Homology Io a Subonit of NADH Dehydrogenase RNA Processing -Cycling Splicing Factors Pusttranscriptional Regulation of Idl Activity in Cardiac Muscle -Alternative Splicing of Novel Idl Transcript Permits Homodimerization RNA Editing of Transcripts of a Chimeric Mitocbondrial Gene Associated with Cytoplasmic Male-slerilily in Brassica Direct Interactions Between Pre-Mrna and Six U2 Small Nuclear Ribonucleoprntelns During Spliceosome Assembly A Sequence Compilation and Comparison of Exons thai are Alternatively Spliced in Neurons Generation of Temperature-Sensitive Cbpl Strains of Saccharomyces Cerevisiae by PCR Mutagenesis and in Vivo Recombinalion -Characteristics of the Mutant Strains Imply that Cbpl is Involved in Stabilization and Processing of Cylochrome B Pre-Mrna Quantitative Analysis of Alternative Splicing Options of Human Plasma Membrane Calcium Pump Genes Multiple Sequence Elemeuts and a Maternal MRNA Product Control Cdk2 RNA Polyadenylation and Translation During Early Xenopus Development The Single Translation Product of the FUM1 Gene (fomarase) is Processed in Mitochondria Before Being Dislributed Between the Cylosol and Mitochondrla in Saccharomyces Cerevisiae Structure Specific Ds/ss-RNase Activity in the Extreme Halophile Halohacteriorn-salinarium PRP28, a 'DEAD-box' Protein, is Required for the First Step of MRNA Splicing in Vitro Proteins Binding to 5' Untranslated Region Sites: a general Mechanism for Translational Regulation of MRNAs in Human and Yeast Ceils Tertiary Interactions with the Internal Guide Sequence Mediate Docking of the P1 Helix into the Calalytic Core of the Tetrahymena Ribozyme A Functional Interaction Between Rev ee and Yeast Pre-mRNA is Related to Splicing Complex Formation Expression of Endogenous NMDAR1 Transcripts Without Receptor Protein Suggests Post-Trauscription Control in PC12-CelIs The Existence of Eukaryotic Ribooncleoproleln Consensus Sequence-Type RNA-Binding Protein~ in a Prnkaryote, Synechococcns 6301 Tethering Ribozymes 1o a Relruviral Packaging Signal for Destrucllon of Viral RNA Ribozyme-mediated Repair of Defective MRNA by Targeted Trans-splicing Ribozyme-mediated Repair of Defective MRNA by Targeted Trans-spliclng The Yeast NOP4 Gene Product is an Essential Nocleolar Protein Required for Pre-rRNA Processing and Accmnulation of 605 Ribosomal Subonits Ribozyme-mediated Suppression of Moloney Murine Leukemia Virus and Human Immunodeficiency Virus Type I replication in Permissive Cell Lines General Splicing Factor SF2/ASF Promotes Alternative Splicing by Binding to an Exonic Splicing Enhancer Several Messenger RNAs with Variable 3' Untranslated Regions and Different Stability Encode the Human PR264/SC35 Splicing Factor The Yeast Ume5 Gone Regulates the Stability of Meiotic MRNAs in Response to Glucose Characterization of Serine and Leocine Trnas in an Asporogeoic Yeast Caodida Cyliodracea and Evolutionary Implications of Genes for TRNA(Ser)Cag Responsible for Translalion of a Non-Universal Genetic Code Structural Model of the 50 S Subonil of Escherichia Colt Ribosomes from Solution Scattering. 2. Neutron Scattering Study Structural Model of Ihe S0 S Subonil of Escherichia Colt Ribosomes from Solution Scattering. 1. X-ray Synchrotron Radiation Study tocalization of an RNA Binding Element of the Iron Responsive Element Binding Protein Within a Proteolytic Fragment Containing Iron Coordination Ligands tntron-dependent Formalion of Pseudouridines in the Anticodoo of Saccharomyces Cerevisiae Minor TRNA(Ile) Alternative Splicing of Class IB Major Histocon~atibility Complex Trauscripts in Vivo Leads to the Expression of Soluble Qa-2 Molecules in Murine Blood A Three-nudeotide Helix I is Sufficient for Full Activity of a Hammerhead Ribozyme: Advantages of an Asymmetric Design Selective Recruitment of Masked Maternal Messenger RNA from Messenger Ribonucleoprolein Particles Containing FRGY2 (Messenger RNP4) A Polyadenylation Factor Subunit • is the Human Homologue of The Drosophila Suppressor OF Forked Protein Alternative 5' Splice Site Selection Induced by Heat Shock Effects of 5-floorouracil Substitution on the RNA Cooformalion and Invitro Translation OF Thymidylate Synlhase Messenger RNA Intron Definition in Splicing of Small Drosophila Introns Role of the CCA Terminal Sequence of TRNA(Val) in Aminoacylation with Valyl-tRNA Synlhetase Polyporine Sequences Within a Downstream Exon Function as a splicing Enhancer Bend and Helical Twist Associated with a Symmetric Internal Loop from 55 Ribosomal RNA Faithful Degradation of Soybean RbcS Messenger RNA Invitro Immunnaflinity Purification of the Escherichia Colt Rne Gene Product. Evidence that the Rne Gene Encodes the Processing Endoribonuclease RNase E Functional Association of Essential Splicing Factor(s) with PRP19 in a Protein Complex Yeast Precursor Messenger RNA Processing Protein PRP19 Associates with the Spliceosome Concomitant with or Just after Dissociation of U4 Small Nuclear RNA Arachidonic Acid Down-Regulates the Insulin-Dependenl Glucose Transporter Gene (GLUT4) in 3T3-L1 Adipocytes by Inhibiting Transcription and Enhancing Messenger RNA Turnover The Splicing Factor Prp2, a Putative RNA Helicase, Interacts Directly with Pre-Mrna Identification and Analysis of the Pseudoknot-containing Gag-pro Ribosomal Frameshift Signal of Simian Retrovirus-1 E: Retention and 5' Cap Trimethylalion of U3 SnRNA in the Nucleus Multiple Cis-Acting Signals for Export of Pre-U1 SnRNA from the Nucleus Phylogenelically Preserved Inter-rRNA Base Pairs: Involvement in Ribosomal Subunit Association Mechanism of Post-Segregational Killing -Translatiou of Hok, Srnb and Pnd MRNAs of Plasmids R1, F and R483 is Activated by 3'-End Processing Segregational Killing -Sok Antiseose RNA Interacts with Hok Mrna Via Its 5'-End Single-Stranded Leader and Competes with the 3'-End of HoE Mrna for Binding to the Mok Translational Initiation Region A Chloroplast Group I Intron Undergoes the Firsl Step of Reverse Splicing into Host Cyloplasmic 5 Center Dot 8 S RRNA -Implications for Intron-Mediated RNA Recombination, Intron Transposition and 5 Center Dot 8 S RRNA Structure Activity of Hammerhead Ribozymes Containing Non-Nudeotidic Linkers Insulin Promotes the Biosynthesis and Secretion of Apolipoprotein B-48 by Altering Apolipopcotein B MRNA Editing Multiple Forms of POly(A) Polymerases in Human Cells A Splicing Enhancer Exhibits Both Constitutive and Regulated Activities Post-Transcriptional Regulation of GlutamyI-Prolyl-tRNA Synlhetase in Rat Salivary Gland. I 8iol Chem The 165 Ribosomal RNA Mutation Database (165MDB) Evolutionary Optimization of the Catalytic Properties of a DNA-cleaving Ribozyme Alternative Splicing of Beta-troponlyosin Pre-mRNA: Multiple Cis-elements can Contribute to the use of the S'-and 3'-splice Sites of the Nonmnscle/smoolh Muscle Exon 6 A Functional Mutanl of Transfer RNA(2)(Arg) with Ten Extra Nucleotides in Its TFC Arm Importance of Exncyclic Base Functional Groups of Central Core Guannsines for Hammerhead Ribozyme Activity Importance of Exocyclic Base Functional Groups of Central Core Guannsines for Functional Characterization of the Alternatively Spliced, Placental Human Growth Hormone Receptor A Conserved Heplamer Motif for Ribosomal RNA Transcription Termination in Animal Mitochondria De Wachter R: Database on Ihe Structure of Small Ribosomal Subunil RNA A Complex Secondary Structure in UIA Pre-Messenger RNA that Binds Two Molecules of U1A Protein is Required for Regulalfoo of Polyadenylatlon Separate Structural Elements Within Internal Transcribed Spacer 1 of Saccharomyces Cerevisiae Precursor Ribosomal RNA Direct the Formation of 17S and 26S RRNA Two Differenl Sequence Elements Within Exon 4 are Necessary for Calcitonin-specific Splicing OF the Human Calcitonin/calcitonin Gene-related Peptide I Pre-mRNA Point Mutations Distal to the Processing Site Affect Drosophila Pre-5 S RNA Proce~ing -Long Range Cooperation and a 8realhing Model Rodili h Control of Polyadenylation and Alternative Splicing of Transcripts from Adjacent Genes in a Procyclin Expression Site: a Dual Role for Polypyrimidine Tracts in Trypanosomes? A Novel RNA Gone in the Tobacco Plastid Genome: Its Po~ble Role in the Maturation Of 165 RRNA Regulation of Splicing at an Intermediate Step in the formation of the spliceosome Influenza a Virus Late • MRNAs are Specifically Retained in the Nucleus in the Presence of a Melhyltransferase or a Protein Kinase Inhibilor Methylation Inlerference Experiments Identify Bases thai are Essenlial for Distinct Catalytic Functions of a Group-I Ribozyme Chicken Mar Binding Protein P120 is Identical to Human Heterogeneous Nuclear Ribonudeoprotein (Hnrnp) U Structural Dependence of Post-Translational Modification and Redoctive Acetylation of the Lipeyl Domain of the Pyruvate Dehydrogenase Multienzyme Complex Coaxial Stacking of Helixes Enhances Binding of Oligoribonucleotides and improves Predictions of RNA Folding The Sex-lethal Amino Terminus Mediates Cooperative Interactions in RNA Binding and is Essential for Splicing Regulalion Visualization of a Tertiary Structural Domain of the Tetrahymena Group I Introo by Electron Microscopy Specific Ammonium Ion Requirement for Functional Ribosomal RNA Tertiary Structure Peptide Antibiotics of the Tuberactinomycin Family as Inhibitors of Group I Intron RNA Splicing Unusual Anlicodon Loop Structure Found in E-Coli Lysine TRNA Ix~nb~ Met2(+) Encodes an RNA-binding Prolein Essential FO¢ Premeiotic DNA Synthesis and Meiosis I, Which Cooperates with a Novel RNA Species MeiRNA Identification of a Small RNA that Interacts with the 5' Splice Site of lhe Trypanosoma-brucei Spliced Leader RNA Invivo Elongation Factor Tu D138N, a Mutant with Modified Substrate Specificity, as a Tool to Study Energy Consumption in Protein Biosynthesis Probing the Interaclioos of POly(U) and TRNA(Phe) with Nucleotides 1530-1542 And 1390-1417 of 16 S RRNA of Escherichia CoB Interactions Between Highly Conserved U2 Small Nuclear RNA Structures and PrpSp, Prpgp, Prpllp, and Prp21p Proteins are Required to Ensure Integrity of the U2 Small Nuclear Ribonocleoprotein in Saccharomyces Cevevislae Nup 145 Encodes a novel Yeast • Glycine.leucine-phenylalanine-glycine (GLFG) Nucleoporin Required for Nuclear Envelope Structure Connecting Anticodon Recognition with the Active Site of Escherichla Coli Glulaminyl-tRNA Synlhetase RNA -Deviants -or Emissaries Posttranscriptional Regulation of the Helerochronic Gone Lin-14 by Lin-4 Mediates Temporal Pattern Formation in C.elegans Selection of Novel Forms of a Functional Domain Within the Tetrahymena Ribozyme Guides to the Heart of the Splicensome Multiple Folded Conformations of a Hammerhead Ribozyme Domain Under Cleavage Conditions Interplay of Heterogeneous Transcriptional Start Sites and Translational Selection of Angs Dictate the Production of Milnchondrial and Cylosolic Nuclear TRNA Nudeotidyltransferase from the Same Gene in Yeast Splicing Function of Mammalian U6 Small Nuclear RNA -Conserved Positions in Central Domain and Helix-I are Essential During the First and Second Step of ere-Messenger RNA Splicing Alternative Splicing Generates Secretory tsoforms of Human CD1 POM 152 is an Integral • Protein of the Pore Membrane Domain of the Yeasl Nuclear Envelope The Binding Site for Ribosomal Protein $8 in 16S RRNA and Spe MRNA fro~ Escherichia colt: Minimum Structural Requirements and the Effects of Single Bulged Bases on Sg-RNA Interaclion Specific Interactions Between Proteins Implicated in Splice Site Selection and Regulated Allernative Splicing The Long Extra Arms of Human Transfer RNA((Ser)Sec) and Transfer RNA(Ser) Function as Major Identity Elements for Serylation in an Often]alton-Dependent, BUt nut Sequence-Specific Manner The Multiplloephorytation Domain of the Phoephoryiase Kinase Alpha(M] and All~a(L) Subunits is a Hotspot of Differential Messenger RNA Processing and of Molecular Evolution Bindereif A: traos-Spliceusomal U6 RNAS of Critbidia Fasciculata and Leptomonas Seymouri: Deviation from the Conserved ACAGAG Sequence and Potential Base Fairing with Spliced Leader RNA Genomic Slruclure and Cloned CDNAS Predict Ihat Four Variants in the Kinase Domain of Serine/lhreuuine Kinase Receptors Arise by Alternative Splicing and Poly(A) Addition Molecular Characlerization of the Mouse Ribosomal Protein $24 Multigene Family -a Uniquely Expressed lutron-Containiog Gene with Ceil-Specific Expse~ino of Three Alternatively Spliced MRNAS Self-splicing Group I Introos in Eukacyotic Vin~,~s Cloning and Mutagenesis of the Rabbit gpoB MRNA Editing Protein -a Zinc Motif is Essential for Catalytic Activity, and Noucatalylic Auxiliary Factor(s) of the Editing Complex are Widely Distributed A Genetic Polymorphism Within the Third POly(A) Signal of the DHFR Gene Alters the Polyadenylatinn Pattern of DHFR Transcripts in CHI Ceils Catalytic Activity of an RNA Domain Derived from Ihe U6-U4 RNA Complex Parathyroid Hormonerelated Protein: Evidence for Isoforrm and Tissuespecific Posttranslalional Processing A DorJble Hairpin Structure is Nece~lry for the Efficient Encapsidation of Spleen Necrosis Virus Retroviral RNA The A1 and AI(B) Proteins of Heterogeneous Nuclear Ribunucleuparticles Modulate 5' Splice Site Selection in Vivo Anticodon Bases C34 and C35 are Major, Pnsilive, Identity Elements in Saccharomyces-cerevlsiae Transfer RNA Postlranslalional Modifications in Microcin B17 Define an Additional Cla~ of DNA Gyrase Inhibitor Duta RNA Functions as an Untranslatable RNA in the Development of Diclyuslelium Discoidenm A Hairpin Ribuzyme Inhibits Expre~ino of Diverse Strains of Human Immunodeficiency Virus Type-1 Functional Reconslitution of U6 SuRNA in Nemalode Cis-Splicing aud Trans-Splicing -U6 can Serve as Both a Branch Acceptor and a 5'-Exon Selection of Guide Sequences that Direcl Efficient Cleavage of Mrna by Human Ribunuclease P Alternative Splicing Governs Sulfa]ion of Tyrosine or Oligosaccharide on Peptidylglycine Alpha-Amidating Monooxygenase Heal Induclion of Sigma(32) Synthesis Mediated by Messenger RNA Secondary Structure. a Primary Step of Ihe Heat Shock Response in Escherichia-coli Analysis of Autoregulalion at the Level of Pre-Mrna Splicing of the Suppressor-of-While-Apricot Gene in Drosophila Mutations in an Essential U2 Small Nuclear RNA Structure Cause Cold-Sensilive U2 Small Nuclear Rib•nude•protein Function by Favoring Competing Alternative U2 RNA Structures Nuclear-Mitotic Apparatus Protein -a Structural Protein Interface Between the Nucleoskeleton and RNA Splicing The 5' Leader of a chloroplast MRNA Mediales the Translational Requirements for Two Nucleus-encoded Functions in Chlamydomonas Reinhardtii Cheah HK~ Saxon A: Complex Alternative RNA Splicing of Epsilon-lmmunoglobulin Transcripts Produces MRNAs Encoding 4 Potential Secreted Protein Isoforms Purification, Characterization, and CDNA Cloning of an AU-Rich Elemenl RNA-Bindiog Protein Novel Action of Retinolc Acid -Stabilization of Newly Synthesized Alkaline Phosphatase Transcripts Lead-Catalyzed Cleavage of Riboonclease P RNA as a Probe for Integrily of Tertiary Structure Hemmings BA: Isolation, Characterization, and Chromosomal Localization of the Porcine Calcitonin Receptor Gene -Identification of Two Variants of the Receptor Generated by Alternative Splicing Functional Domains of the Human Splicing Factor ASF/SF2 The Human Splicing Faclor ASF/SF2 can Specifically Recognize Pre-Messenger RNA 5' Splice Sites DNA Methylation Prevents the Amplification of TROP1, a Tumorassociated Cell Surface Antigen Gene Developmental Changes in Methylation of Spermatogenesis-Specific Genes Include Reprogramming in the Epididymis Signer ER: I:pigenetic Repeal-induced • Gene Silencing (RIGS) In Arabidopsis Methylation Patterns in PAP Regulatory DNA Control Pyeionephrilis-A~nciated Pill Phase Variation in E-Colt Spl Elements Protect a CpG Island from De Nov• Methylation The Ontogeny of Allele-specific Methylation Associated with Imprinled Genes in the Mouse Pervasive CPG Suppression in Animal Mitochondrial Genomes Lack of Expression from a Retroviral Vector after Transduction of Murine Hematopoietic Stem Cells is Associated with Methylatlon Invivo The Domains of a Type I DNA Methyltransferase -Interactions and Role in Recognition of DNA Methylation Methylation-related Chromatin Structure is Associated with Exclusion of Transcription Factors from and Suppressed Expre~ion of the O-6-methylguanine DNA Methyltraosferase Gene in Human Glioma Cell Lines Graded Methytation in the Promoter and Body of the O-6-methylguanine DNA Methyltransferase (MGMT) Gene Correlates with MGMT Expression in Human Glioma Ceils Xce Haplotypes Show • Modified Methylation in a Region of the Active X chromosome Lying 3'to Xist W: Developmental • • Control of Allelic Methylation in the Imprinted Mouse 18f2 and HI9 Genes Inactivation of Gene Expression in Plants as a • Consequence of Novel Sequence Duplication Abnormal ¢• Chrornosome Behavior in Neuro~oora mutants Defective in DNA Methylation De Nov• Methylation of Repeated Sequences in Copriuus Cinereus Molecular and Cellular Characterization of Mex-/Methylalion-Resistant Phenotype -Gene and CDNA Cloning, Serum Dependence, and Tumor Suppression of Transfectant Strains Methylation of Single Sites Within the Herpes Simplex Virus TE Coding Region and the Simian Virus 40 T-Antigen Intron Causes Gene Inactivation Silencing of Ihe VHL Tumor-suppressor Gene by DNA Methylation in Renal Carcinoma High-resofution Methylation Analysis of the Human Hypoxanthine Phosphoribosyltransferase Gene 5' Region on the Active and Inactive X chromosomes: Correlalion with Binding Sites for Transcription Factors Dependence of Transcriptional Repression on CpG Methylalion Density • Posllranscriptional Silencing of Reporter Transgenes in Tobacco Correlates with DNA Methylation Melhylation of the Oeslrogen Receptor CpG Island Links Ageing and Neoplasia in Human Colon A Nuclear Protein with Enhanced Binding to Methylated Spl Sites in the AIDS Virus Promoter Inactive Chromatin Spreads from a Focus of Methylalion Methylation Profiles of Genomic DNA of Mouse Developmental Brain Detected by Restriction Landmark Genomic Scanning (RLGS) Method Positioned Nucleus•rues Inhibit Dam Melhylation in Vivo Hhal Methyltraosferase Flips Its Target Base Out of the DNA Helix Symmetrical Model for the Domain Structure of Type I DNA Methyllrausferases Differences in the Accessibility of Methylated and Unmethylated DNA to DNAse I Conserved Sequence Motif DPPY in Region-IV of the Phage-T4 Dam DNA.[N6-adenine]-methyhraosferase is Important for S.adenosyI-L-methioninc Binding Histone-HI-Mediated Inhibition of Transcription Initiation of Methylated Templates Invitro Role for DNA Methylation in • • Genomic Imprinting B Cell-Specific Demethylation -a Novel Role for the Intronic Kappa Chain Enhancer Sequence Methylation Sensitivity of the Enhancer from the Human PapUlomavirus Type 16 Alu Transcripts -Cytoplasmic Localisafion and Regulation by DNA Methylation Spl Sites in the Mouse Aprt Gene Promoter are Required to Prevent Methylation of the CpG Island Ubiquitous and Tenacious Methylallon of the CpG Site in Cedon 248 of the P53 Gene May Explain Its Frequent Appearance as a Mutational Hot Spot in Human Cancer A Molecular Rheostat -Co-operative Rev Binding to Stem I of the Rev-respuose Element Modulates Human Immunodeficiency Virus Type-1 Late Gene Expression Coordinate Suppression of • Mutation Caused by Robertson's Mutator Trar-rq~nsons in Maize Differential Expression of a New Dominant Agouti Allele (A lapy ) is Correlated with Methylation State and is Influenced by Parental Lineage The Topology of the Promoter of RNA Polymerase II-and III-transcrihed Genes is Modified by the Melhylatlon of 5'-CG-3' Dinuclenlldes Dissection of the Methyl-CpG Binding Domain from the Chromosomal Protein MeCP2 Evidence Ihat Random and Imprinted Xist Expression is Controlled by Preemptive Methylalion Paramutation, an • • Allelic Interaction, is Associated with a Stable and Heritable Reduction of Transcription of the Maize B Regulatory Gene DNA Methylation Represses the Murine Alpha 1(I) Collagen Promoter by an Indirect Mechanism Progressive Increases in the Methylation Status and Heterochromatinization of the MyoD CpG Island During Oncogenic Transformation Epigenctic Regulation • of the Maize Si~n Transposable Element: Novel Activation of a Melhylated Promoter hy TnpA Dense Nousymmelrical DNA Methylation Resulting from Repeat-Induced Point Mutation in Neurospora Functional Requirement of a Site-Specific Ribose Melhylalion in Ribosomal RNA Hypermethylation of Telomece-like Foldbacks at Codon 12 of Ihe Human C-Ha-ras Gene and the Trinocleotide Repeat of the FMR-1 Gene of Fragile X Maternal-sl)eclfic Methvlatlon of the Imprinted Mouse Igf2r Locus Identifies the Expressed Locus as Carrying the Imprinting Signal Deletions of a differentially Methylated CpG Island at the SNRPN Gone Define a putative Imprinting Control Region Substrale Recognition and Selectivity in the Type-IC DNA Modification Methylase M.EcoRI1241 The Flip Side of DNA Melhylation RNA-Directed De Novo Methylation of Genomic Sequences in Plants DNA Methylation by N-methyI-N-nilrosourea -Methylation Pattern Changes in Single-Stranded and Double-Stranded DNA, and in DNA with Mismatched or Bulged Guanir.es The Functional Sul~nit of a Dimeric Transcription Activator Protein Depends on Promoter Architecture Chromosome structure, imprinting and segregation Related reviews: Sister cflromatid separation in vivo and in vitro Telomeres and telomerase in aging and cancer Position Effect Variegation at Fission Yeast Centromeres Chromosome End Formation and Inlernal Sequence Elimination as Alternative Genomic Rearrangements in the Ciliate Paramecium A Mismatch Recognition Defect in Colon Carcinoma Confers DNA Micrnsatelllte Instability and a mutator Phenotype Functional Recoostitution • • of Wild-type and Mutant Tetrahymena telomerase Mode of Dimerization of HIV-1 The Twist, Writhe and Overall Shape of Supercoiled DNA Change During Counterion-lnduced Transition from a Loosely to a Tightly Interwound Superhelix -Possible Implications for DNA Structure Invivo Differential Effects of Sex-Lethal Mutations on Dosage Compensation Early in Drosophila Development Novel Control of the Position-Dependent Expre-~ion of Genes in Hepatocyles -the GLUT-1 Transporter Periodicity of Dinucleolides in Nucleosomes Derived from Simian Virus 40 Chromatin Weakener of While (Wow), a Gene that Modifies the Expression of the White Eye Color Locus and that Suppresses Position Effect Variegation in Drosophila Melanogaster Telomeres: no End in Sight Acetylated Histone H4 on the Male X-Chromosome is Associated with Dosage Compeosation in Drosophila Large-scale Opening of A+T Rich Regions Within Supercoiled DNA Molecules is Suppre~ The Rapid Transfer and Selective Association of Histories H2A and H2B Onto Negatively Coiled DNA at Physiological Ionic Strength The Human X-Inactivation Centre is not Required for Maintenance of X-Chromosome Inadivation A Polycomb Response Element Inthe Ubx Gene that Determines an Epigenetically Inherited State of Repression Effect of Positive Supercoiling on DNA Compaction by Nucleosome Cores Partitioning of Plasmid R1 -Ten Direct Repeats Flanking Ihe Para Promoter Constitute a Centromere-Like Partition Site Parc, that Expres6es Incompatibility The Effects of Noclentide Sequence Changes on DNA Secondary Structure Formation in Escherichia Co~i are Consistent with Cmclform Extrusion in Vivo The Enhancer of Positlon-Effect Variegation of Drosophila, E(var)3-93D, Codes for a Chromatin Protein Containing a Conserved Domain Common to Several Transcriptional Regulators Nuclensomal Slructore al Hypecacetylated Loci Probed in Nuclei by DNA Histone Crnsslinking Mutations in Rikl, CIr2, CIr3 and CIr4 Genes Asymmetrically Derepre~ the Silent Mating-Type Loci in Fission Yeast Enhancement of Telomere-plasmid Segregation by the X-Telomere AsSociated Sequence in Saccharomyces Cerevisiae Involves Sir2, Sir3, Sir4 and Abfl Flare F: Molecular Imprints Make a Mark Reduced Dosage of Genes Encoding Ribosomal Protein $18 Suppre~es a Mitochondrial Initiation Codon Mutation in Saccharomyces Cerevisiae Point Mutations Ihat Separate the Role of Saccharomyces Cerevisiae Centromere Binding Factor-1 in Chromosome Segregation from Its Role in Transcriptional Activation Molecular Definition of the PASI-1 Mutation Which Affects Silencing in Saccharomyces Cecevisiae Cerevisiae • 265 Protease Mutants Arrest Cell Division in G2/metaphase Promotion of Parallel DNA Quadruplexes by a Yeasl Telomese Binding Protein: a Circular Dichroism Study • Defective Mitosis Due to a Mutation in the Gene for a fission Yeast Protease Subunit Stringent Sequence • . Requirements for the Formation of Human Telomeres Telomerase, Cell Immortality, and Cancer. Cold Spring Harb Symp Quant Biol Mukai 1: A New Imprinted Gene Cloned by a Methylation-Ser-~tive Genome Scanning Method Mutagen Sensitivity and Suppression of Posltion.Effect Variegation Result from Mutations in Mus209, the Drosophila Gene Encoding PCNA Dosage Compensation in Drosophila: the x-Chromosomal Binding of MSL-1 and MLE is Dependent on Sxl Activity Temperature Sensitivity of Negative Segregation Distortion in Drosophila Melanogaslec Anaphase • is Initiated by Prutenlysis Rather Than by the Inactivalion of MPF Coming Undone: How Io Untangle a chromosome High-resolution Methylation Analysis of the Human Hypoxanthine Phnsphoribosyltransferase Gene 5' Region on the Active and Inactive X chromosomes: Correlation wilh Binding Sites for Transcriptiou Factors C: DBF8, an Essential Gene Required for Efficient Chromosome Segregation in Saccharomyces Cerevisiae Genetic Imprinting -Taking Stuck in Stockholm Mixed Segregation and Recombination of Chromosomes and Yacs During Single-Division Meiosis in Spo13 Strains of Saccharomyces Cerevisiae Inhibition of DNA Topoisumerase II by ICRF 193 Induces Polyploidization by Uncoupling Chromosome Dynamics from Other Celt Cycle Events Complex Gene Conversion Evenls in Germline Mutation at Human Minisalellites Binding Specificity of a Nuclear Scaffold -Supercoiled, Single-Stranded, and Scaffold-Atlacbed-Region DNA Chromatin Structure Modulation in Saccharomyces CeTevisiae by Centromere and Promoler Factor 1 Triple Helix Formation at Distant Sites -Hybrid Oligonueleutides Containing a Polymeric Linker Cutting GR: A Mutation in CFTR Produces Different Phenotypes Depending on Chromosomal Background Specific Associalion of Human Telomerase Activity with Immortal Cells and Cancer. Science 'i994 The Non-B-DNA Slruclure of D(Ca/'TG)N Differs from lhal of Z-DNA Allele Specificity of DNA Replication Timing in the Angelman/ Prader-Will] Syndrome Imprinted Chromosomal Region Identification and Cloning of the CHL4 Gene Controlling Chromosome Segregation in Yeast Chromosome Breakage at a Major Fragile Site Associated with P-glycoprotein Gene Amplification in Multidrug-resistaut CHO Cells Igf2R and Igf2 Gene Expression in Androgenetic, Gynogenetict and Parthenogenetic Preimplantalion Mou~e EmbryOS -Absence of Regulation by Genomic Imprinting On the Location of Linker DNA in the Chromatin Fiber -Studies with Immobilized and Soluble Micrucuccal Nuelease Role for DNA Methylation in Genomic Imprinting Telomerase RNAs • of Different Ciliates have a Common Secondary Structure and a Permuted Templale The Yeast KEM1 Gene Encodes a Nuclease Specific for G4 Telraplex DNA: Implication Of in Vivo Functions Far This Novel DNA Structure Left-handed Z-DNA and in Vivo Supercoil Density in the Escherichia Colt Chromosome • Interphas~ Chromnsucnes of Friend-S Cells are Attached to the Matrix Structures Through the Cenlromeric/telomeric Regions Neonatal Imprinting Predetermines the Sexually Dimorpbic, Estrogen-Dependent Expression of Galanin in Luteinizing Hormone-Releasing Hormone Neurons A MAP Kinase-• dependent Spindle Assembly Checkpoint in Xenopus egg Extracts Double or Nothing -a Drosophila Mutation Affecting Meiotic Chromosome Segregation in Both Females and Males Evidence that a Complex Of SIR Proteins Interacts with the Silencer and Telomere Binding Protein RAP1 An Analysis of Interference in the Fission Yeast Schizosaccharomyces Pombe Structural and Functional Conservation of the Human Homolog of the Schiznsaccharomyces Pomhe Rad2 Gene, Which is Required for Chromosome Segregation and Recovery from DNA Damage Ca/TG Sequence at the 5' End of Oligo(A)-Tracts Strongly Modulates DNA Curvature Effects of Various Salts and PH on the Stability of the Nuclensome in Chromatin Fragments Cpfl Protein Induced Bending of Yeast Centromere DNA Element-1 Leptomycin B Targets a Regulatory Cascade of Crml, a Fission Yeast Nuclear Prolein, Involved in Control of Higher Order Chromosurne Structure and Gene Expression Rastan S: Evidence that Random and Imprinted Xist Expression is Controlled by Preemptive Melhylation Telomere Maintenance and • Gene Repression: a Common End? Wu Ch Characlerization of 2 Segregation-Distorter Revertants -Evidence that the Tandem Duplication is Necessary for Sd Activity in Drosophila Meianogaster The Anti Z-DNA Reactivity of Z.DNA Forming Sequences is Affected by Platinum Ant]tumor Drugs A Chlamydomonas Protein that Binds Single-Stranded G-Strand Telomere DNA Allele-specific Gene Expression in Mammals: the Curious Case of the Imprinted RNAs The Yeast Medl Mutant Undergoes Both Meiotic Homolog Nondisjunction and Precocious Separation of Sister Chromatids Bacterial Chromosome Segregation Sister Chromalid Separation in • e Frog Egg Extracts Requires DNA Topolsomerase II Activity During Anaphase TLCI: Template RNA ee Component of Saccharomyces Cerevisiae Telomerase Essenlial Role for KH Domains in RNA Binding: Impaired RNA Binding by a Mutation in the KH Domain of FMR1 thai Causes Fragile X Syndrome Hypermethylation of Telomere-like foldbacks at Codon 12 of the Human C-Ha-ras Gene and the Trinucleotide Repeal of the FMR-t Gene of Fragile X DNA Class Organization on Maize Adhl Yeast Artificial Chromosomes. Pro( Natl Acad Sci U S A Destruction of the CDC28/CLB Mitotic Kinase is not Required for the Metaphase to Anaphase Transition in Budding Yeast Genomic Imprinting -Silence of the Genes Deletions of a differentially Methylaled CpG Island at the SNRPN Gene Define a putative Imprinting Control Region Multiple Chromosomal • Populations of Topoisomerase II Detecled in Vivo by Time-lapse, Three-dimensional Wide-field Microscopy Modification of the Drosophila Heterochromatic Mutation Brown(Dominant) by Linkage Alterations Transcription Through the Yeast Origin of Replication ARS1 Ends at the ABEl Binding Site and Affects Extrachromosomal Maintenance of Minicbromosomes Excision Close to Matrix Attachment Regions of Ihe Entire Chicken Alpha-globin Gene Domain by Nuclease $1 and Characterization of the Framing Structures Alu Sequence Involvement in Transcriptional Insulation of the Keratin 18 Gene in Transgenic Mice Unusual • • Chromalin in Human Telomeres. MOI Cell Bio11994 DNA Chaperons: a Solution to a Persistence Problem The Dynamics of Chromatin Condensalion -Redistribution of Topoisumerase-II in The 87A7 Heat Shock Locus During Induction and Recovery Evidence for a Mitotic Cluck in Human Hematopoielic Stem Cells: Loss Of Telomeric DNA with Age ChromoSome Pairing Via Multiple Interstitial Interactions Before and During Meiosis in Yeast The Murine Xe169 Gene Escapes X-inactivation Like Its Human Homologue Yeast Srplp Has Homology to Armadillo/plakoglobiu/hetacatenin and Participates in Apparently Multiple Nuclear Functions Including the Maintenance of the Nucleolar Structure A Complex Mutable Polymorphism Lucated Within the Fragile X-Gene