key: cord-0042541-d2z556s0 authors: Decaro, Nicola title: Betacoronavirus(‡): Coronaviridae date: 2011 journal: The Springer Index of Viruses DOI: 10.1007/978-0-387-95919-1_57 sha: 6b529c8c7c90df3e753b94eb1125b52f696828a5 doc_id: 42541 cord_uid: d2z556s0 nan Murine hepatitis coronavirus (MHV) associated with encephalomyelitis in mice Cheever et al (1949) 1967 HCoV-OC43 isolated from patients with common cold McIntosh et al (1967) 1968 Electron microscopy reveals that BCoV has a second, short surface protein (HE) Bridger et al (1978) 1975 ICTV approves Coronaviridae family with one genus, Coronavirus Tyrrell et al (1975) 1981 Spike protein shown to be responsible for membrane fusion Holmes et al (1981) 1982 Leader sequence at 5 0 of mRNAs is from 5 0 of genome (MHV) Lai et al (1982) Year of event Event References First coronavirus gene (N) sequenced (MHV) Skinner and Siddell (1982) 1983 Leader-primed transcription model proposed (MHV); discontinuous transcription during positive strand synthesis Lai et al (1983) 1984 M protein (MHV) is located in Golgi membranes Tooze et al (1984) 1985 Near start of genes is a sequence similar to 3 0 end of the leader RNA at 5 0 end of the genome (MHV) Budzilowicz et al (1985) 1985 Coronavirus defective RNAs discovered (MHV) Makino et al (1985) 1985 Homologous recombination achieved with MHV Lai et al (1985) . Cavanagh et al (1997) 1996 ICTV recognises the order Nidovirales containing families Coronaviridae and Arteriviridae Cavanagh et al (1997 Cavanagh et al ( ) 1996 M and E proteins sufficient for the formation of virus-like particles Bos et al (1996) ; Vennema et al (1996 Vennema et al ( ) 1997 Insertion of gene for green fluorescent protein into genome of MHV by recombination Fischer et al (1997) 2000 In-vitro construction of chimeric coronaviruses that cross the species barrier Kuo et al (2000) 1999 Insertion of a transcription control sequence into MHV by recombination Hsue and Masters (1999) Coronaviridae: the viruses and their replication The coronaviridae. New York, Plenum Sturman and Holmes Real-time RT-PCR amplification of the membrane protein gene (2006)