key: cord-0068740-il7jf35v authors: Itani, Leila; Sammarco, Rosa; El Ghoch, Marwan title: Editorial: Nutrition and Health-Related Quality of Life: Is It an Ignored Outcome? date: 2021-10-07 journal: Front Nutr DOI: 10.3389/fnut.2021.778816 sha: 1e89b59beffde8d16e2b1759b5f41f599cf17ea9 doc_id: 68740 cord_uid: il7jf35v nan The concept of quality of life (QoL) represents the well-being of people living in a certain society, broadly including physical health, family, education, employment, wealth, religious beliefs, finance and the environment (1). In the last three decades, a new dimension of QoL has increased in interest and has become known as the "health-related quality of life" (HRQoL) (2) , which assesses how the individual's well-being may be affected over time, either as a result of a disease, disability or disorder. In fact, the research which focused on HRQoL is extremely important, since its assessment helps monitor progress in terms of achieving the nation's health objectives (3), through its influence on current and future treatments, and health protocols across a wide spectrum of diseases (4) . On the other hand, nutrition is a vital process through which human beings retrieve energy needed for reproduction, growth and development, as well as health maintenance (5). In fact, overand malnutrition are both associated with medical diseases (6) and psychological disorders (7) . It must be remembered that the management of many of these conditions is the result of adequate nutrition (8) (9) (10) . However, and despite this fact, there is a lack of knowledge relating to the link between nutrition and HRQoL (6), consequently, our Research Topic is entitled: "Nutrition and Health-Related Quality of Life: Is it an Ignored Outcome?" so as to attract investigators from different backgrounds, interested in both areas, namely, human nutrition and HRQoL, in order to clarify the link between the two and the nature of their interaction. We received 17 submissions; six of these were declined following an initial editorial assessment. Eleven papers were accepted after one or more rounds of peer revision as follows: 1 clinical trial, 7 original research documents, 1 systematic review, 1 data report and 1 commentary, sourced from 11 different countries. Di Iorio et al. reported on the beneficial effect of 30-min monthly sessions over 12 months in patients with type 2 diabetes mellitus, using an "Individualized Nutritional Therapy, " based on counting carbohydrates, which improved the patients' state of health, preventing cardiovascular risk and exponentially impacting their QoL. Yue et al., in a pilot study, tested the feasibility and impact of a nutritional support strategy on the clinical outcomes of severe and critical patients with SARS-CoV-2 pneumonia, based on underfeeding, which restricted non-protein calories but preserved protein intake. Following the same theme, De Pipaòn et al. argued in a commentary that consumer reports of "Keto Flu" were associated with a ketogenic diet. Liu et al. conducted a large, multicentre, prospective study, composed of 9,996 participants, aged 65 years and older. Their nutritional status and HRQoL were measured using the Mini Nutritional Assessment-Short Form (MNA-SF) and the EuroQoL, respectively. The authors found that higher MNA-SF scores were related to an improved HRQoL. Chen et al. identified an inflammatory-nutritional marker in a study composed of patients with acute kidney injury (AKI), that could predict mortality in this population; a higher PCT to Albumin ratio was strongly associated with higher mortality in sepsis-induced AKI patients. Gathercole et al. compared the impact of the two dietary interventions modification of dietary protein intake over a period of 10 weeks on the host fecal proteome in elderly males, who either met the minimum dietary protein recommendations (RDA) or consumed twice the recommended dietary allowance (2RDA). Lachaud et al. examined the housing trajectories of homeless people with mental illness over a follow-up period of 6 years, and the association of these trajectories with food security. Authors in this study reported that individuals with substance use disorder, who never moved into stable accommodation, had the lowest food security status. Wu et al. investigated the associations of diet quality, physical activity (PA), sedentary behaviors (SB) and HRQoL among children with mental health disorders. They found that health promotion programs, which focused on promoting a highquality diet, increased PA, a better HRQoL and reduced SB among children, could contribute to improving mental health. Gao et al. evaluated the effect of home enteral nutrition on nutritional status, body composition (BC), HRQoL and other clinical outcomes in malnourished patients with intestinal failure. It was found that home enteral nutrition improves nutritional status, BC and HRQoL. Wang et al. conducted a systematic review of controlled trials (RCTs) to explore the efficacy of a low-FODMAP diet (LFD) with regard to alleviating the symptoms of irritable bowel syndrome (IBS). They found that an LFD is effective in reducing the global symptoms and improving the bowel habits of adult patients with IBS. Leão et al. explored the association between nutritional status and functional status among older adults receiving assistance from the in-home nursing care service. The primary finding of this study was that better functional status is directly associated with good nutritional status. All the studies included in this Research Topic either directly or indirectly explored the link between nutrition and HRQoL, based upon which we can identify two types of interaction: (1) bi-direction interaction: in other words, a good nutritional status leads to a better HRQoL and viceversa or (2) synchronic interaction: the two interact with one other to impact another outcome, i.e., an adequate nutritional status plus adoption of a good QoL may improve a medical disease or a psychological disorder. Clearly, future research is still needed to replicate these findings and to consolidate them. In conclusion, we are grateful to "Frontiers in Nutrition" for giving us the opportunity to serve as editors for this Research Topic; it has been such a challenging and motivating experience from which we have learned a great deal and which we intend to continue. Secondly, we would like to thank our valuable authors for sharing their research in this collection, which we believe will have relevance for the readership in their clinical practice. Last but not least, we wish to thank our reviewers for their time and input, which undoubtedly improved the quality of our studies. Quality of life: concept and definition Quality of life measurement: bibliographic study of patient assessed health outcome measures Meeting the healthy people 2020 goals: using the Health Information National Trends Survey to monitor progress on health communication objectives Assessment of quality-of-life outcomes Is there a link between nutrition, genetics, and cardiovascular disease? Depression as a correlate of starvation in patients with eating disorders Nutritional guidelines for the management of insulin resistance Dalle Grave R. The association between weight gain/restoration and bone mineral density in adolescents with anorexia nervosa: a systematic review Lifestyle modification in rheumatoid arthritis: dietary and physical activity recommendations based on evidence All authors claim authorship, and have approved and made substantial contributions to the conception, drafting and final version of the paper. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.