key: cord-0689195-p0945n0u
authors: Fernández‐de‐las‐Peñas, César; Martín‐Guerrero, José D.; Navarro‐Pardo, Esperanza; Torres‐Macho, Juan; Guijarro, Carlos; Pellicer‐Valero, Oscar J.
title: Exploring the recovery curve for gastrointestinal symptoms from the acute COVID‐19 phase to long‐term post‐COVID: The LONG‐COVID‐EXP‐CM Multicenter Study
date: 2022-03-26
journal: J Med Virol
DOI: 10.1002/jmv.27727
sha: aec0d5cfea8e6bf5bcdcfcabb147b54c89a74258
doc_id: 689195
cord_uid: p0945n0u

nan

Exploring the recovery curve for gastrointestinal symptoms from the acute COVID-19 phase to long-term post-COVID: The LONG-COVID-EXP-CM Multicenter Study

To the editor,

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mainly affects the respiratory system; however, extrapulmonary (e.g., gastrointestinal or musculoskeletal) symptoms are also experienced during the acute phase. 1 The presence of gastrointestinal symptoms, particularly diarrhea, at onset is associated with hospitalization 2 and represents an overall risk factor for poor hospitalization outcomes and increased severity. 3 These symptoms are also present after the acute phase.

Previous studies reported a prevalence of gastrointestinal post-COVID symptoms ranging from 10% to 25%. 4 

Extrapulmonary complications of COVID-19: a multisystem disease

Association of digestive symptoms and hospitalization in patients with SARS-CoV-2 infection

Gastroenterology manifestations and COVID-19 outcomes: a meta-analysis of 25,252 cohorts among the first and second waves

Potential long COVID-19 gastrointestinal symptoms 6 months after coronavirus infection are associated with mental health symptoms

Gastrointestinal sequelae 3 and 6 months after hospitalization for Coronavirus Disease

Post-acute COVID-19 syndrome (PCS) and health-related quality of life (HRQoL): a systematic review and meta-analysis

SARS-CoV-2 and the gastrointestinal (GI) system: a structured review

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2-related disease