key: cord-0701063-n1tenk1o authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj title: Acute kidney injury, mortality, and COVID‐19: Correspondence date: 2022-04-12 journal: Ther Apher Dial DOI: 10.1111/1744-9987.13849 sha: c96bf77d7c6a4935986a605a911fd8eab22f8ac5 doc_id: 701063 cord_uid: n1tenk1o nan Dear Editor, We would like to share ideas on the publication "The incidence of acute kidney injury (AKI) and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care uni. 1 " Bayrakci et al. noted that "AKI is frequently seen during the course of COVID-19 and is associated with high mortality. Identifying AKI-related risk factors appears essential in the management of COVID-1. 1 " We agree that AKI is a possible clinical problem in coronavirus disease-2019 (COVID-19). Background medical problems might be a risk for developing AKI and the finding in the present study also support this fact. In an early report from Asia during the early emerging COVID-19, the AKI is rare. 2 Whether the observed incidence in the present study by Bayrakci et al. reflects a possible high background incidence of silent kidney problem is a question. Regarding the mechanism that causes AKI in COVID-19, it is still unclear. Abnormal immunopathology and immune complex formation might be a possible mechanism. 3 Additionally, a change in blood viscosity in COVID-19 might also aggravate AKI. 4 The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit Online ahead of print Novel coronavirus infection (COVID-19) and renal failure: an observation from cases in the 1(st) month of outbreak Coronavirus-antibody immune complex: a nanostructure appraisal possible cause of nephropathology Blood viscosity of COVID-19 patient: a preliminary report