key: cord-0723222-w4pqzbcr
authors: Joob, Beuy; Wiwanitkit, Viroj
title: Chilblains‐like lesions and COVID‐19
date: 2020-05-26
journal: Pediatr Dermatol
DOI: 10.1111/pde.14238
sha: 9ddb22c986bda28a4d5e9609d9bd0e2c77455307
doc_id: 723222
cord_uid: w4pqzbcr

The publication entitled “Chilblains‐like lesions in children following suspected Covid‐19 infection” is very interesting [1]. Colonna et al. reported four children with suspected COVID‐19 cases with “[h]istology from one case showed signs of vasculitis with evident fibrin thrombus [1].” While various skin findings have been reported with COVID‐19 infection, the chilblains lesions have been reported from Italy and Spain, and sporadically from China, the starting point of disease pandemic [2‐5].

This article is protected by copyright. All rights reserved Dear Editor, The publication entitled "Chilblains-like lesions in children following suspected Covid-19 infection" is very interesting [1] . Colonna et al. reported four children with suspected COVID-19 cases with "[h]istology from one case showed signs of vasculitis with evident fibrin thrombus [1] ."

While various skin findings have been reported with COVID-19 infection, the chilblains lesions have been reported from Italy and Spain, and sporadically from China, the starting point of disease pandemic [2] [3] [4] [5] .

However, it should be noted that chilblains-like lesions have not been reported from endemic areas in tropical areas (such as Southeast Asia and South America). For example, in our country, Thailand, we have not seen any patients presenting with this skin finding despite having over 3,000 cases reported as of 11 th May 2020. The rarity of chilblains-like lesions in tropical countries suggests the importance of weather, particularly cold exposure, as a possible co-factor for this vasculopathy noted in associated with in COVID-19 infection. Pathophysiologically, chilblains can result from an excessive abnormal vascular response to cold that leads to cutaneous inflammation.

None

Chilblains-like lesions in children following suspected Covid-19 infection

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Accepted Article This article is protected by copyright. All rights reserved

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