key: cord-0733624-v9mlb3m8
authors: Cavuoto, Kara M.
title: Reply
date: 2021-07-21
journal: J AAPOS
DOI: 10.1016/j.jaapos.2021.02.015
sha: d953d3e4f23f831b9704987f28f3c85678fdc486
doc_id: 733624
cord_uid: v9mlb3m8

nan

Letter to the Editor REPLY We thank Dr. Goncalves dos Santos Martins for his interest in our case report of a previously healthy young man who developed a unilateral abducens nerve palsy in the setting of an acute infection with the SARS-CoV-2 virus. 1 This case highlights the neurologic manifestations that may occur in COVID-19. We appreciate the fact that not only has COVID-19 since been associated with cranial neuropathies, as mentioned by Dr. Goncalves, but also with other neurologic manifestations, including optic neuritis and Miller-Fisher syndrome. 2 Although various possible mechanisms for neurologic involvement have been proposed, we agree that the possibilities include increased intracranial pressure as well as coagulopathies. 3, 4 Additionally, other viruses can also cause cranial neuropathies, including herpes, Chikungunya, and Epstein-Barr virus, and the mechanisms by which these viruses exert their neurologic manifestations may aid our understanding of infections with SARS-CoV-2. Therefore, as our knowledge of the short-and long-term manifestations of COVID-19 increases, we hope that future therapies may limit and/or even prevent these potentially devastating manifestations. 

Acute abducens nerve palsy in a patient with the novel coronavirus disease (COVID-19)

Neuro-ophthalmic manifestations of coronavirus disease 19

Isolated intracranial hypertension associated with COVID-19

Systemic coagulopathy in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis