key: cord-0780735-qrak9b2v
authors: Lin, Jilei; Duan, Jun; Tan, Tingdan; Fu, Zhou; Dai, Jihong
title: The isolation period should be longer: Lesson from a child infected with SARS‐CoV‐2 in Chongqing, China
date: 2020-04-03
journal: Pediatr Pulmonol
DOI: 10.1002/ppul.24763
sha: d46cc98fdd67a909048957ffbc812b169a97d1a4
doc_id: 780735
cord_uid: qrak9b2v

In December 2019, COVID‐19 caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) outbroke in Wuhan, the capital city of Hubei province, China. The disease rapidly spread to other areas in China due to a huge population movement during the New Year Festival. Here, a 7‐year‐old child with SARS‐CoV‐2 infection in Chongqing, outside of Wuhan, Hubei province, was reported. This case suggested that children infected with SARS‐CoV‐2 are more likely to present milder manifestations than adults. The continuous positive real‐time reverse transcription‐polymerase chain reaction assay for SARS‐CoV‐2 in the child's throat swab sample indicated the isolation period for suspected child cases should be longer than 14 days.

A 7-year-old girl was admitted to a quarantine ward in a local country hospital of Chongqing, China, with complaint of nasal obstruction for 2 days without cough, fever, dyspnea, or diarrhea.

Before checking into the quarantine ward, the throat swab sample of this child was tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) assay in Chinese Center for Disease Control and Prevention (CDC). The child's axillary temperature was 36.6℃, with the respiratory rate (RR) of 19 breaths/min, heart rate (HR) of 101 beats/min, blood pressure of 106/65mm Hg. The physical examination showed no apparent rhonchi or moist rales at admission to the hospital.

The girl's father worked in Shanxi province and took the car from Taiyuan, Shanxi province to Jingzhou, Hubei province on January 21, 2020 and then took a bus to Xiangyang, Hubei at that night. On January 22, 2020, the father self-drove from Xiangyang, Hubei to Chongqing city with the girl, her grandparents, mother, In conclusion, this is a case that an adult was infected by a relatively asymptomatic child. It helps us to recognize that children infected with SARS-CoV-2 may be more likely to develop mild symptoms and could be potential sources of infection. The Abbreviations: ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, c reactive protein; CT, computed tomography; DBP, diastolic blood pressure; Hb, hemoglobin; HR, heart rate; LDH, lactate dehydrogenase; NPA, nasopharynx aspirate; PCR, polymerase chain reaction; PCT, procalcitonin; RBC, red blood cells; RR, respiratory rate; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SBP, systolic blood pressure; WBC, white blood cells.

Origin and evolution of pathogenic coronaviruses

Severe respiratory illness caused by a novel coronavirus

Isolation of a Novel Coronavirus from a man with pneumonia in Saudi Arabia

Planning for epidemics-the lessons of SARS

Early transmission dynamics in Wuhan, China, of Novel Coronavirus-infected pneumonia

The isolation period should be longer: Lesson from a child infected with SARS-CoV-2 in Chongqing

We thank the patient; the nurses and clinical staff who are providing care for the patient.

The authors declare that there are no conflict of interests.

http://orcid.org/0000-0003-1920-9317